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Common variants at 12q15 and 12q24 are associated with infant head circumference

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Common variants at 12q15 and 12q24 are associated with infant head circumference. / Taal, H. Rob; St Pourcain, Beate; Thiering, Elisabeth; Das, Shikta; Mook-Kanamori, Dennis O.; Warrington, Nicole M.; Kaakinen, Marika; Kreiner-Moller, Eskil; Bradfield, Jonathan P.; Freathy, Rachel M.; Geller, Frank; Guxens, Monica; Cousminer, Diana L.; Kerkhof, Marjan; Timpson, Nicholas J.; Ikram, M. Arfan; Beilin, Lawrence J.; Bonnelykke, Klaus; Buxton, Jessica L.; Charoen, Pimphen; Chawes, Bo Lund Krogsgaard; Eriksson, Johan; Evans, David M.; Hofman, Albert; Kemp, John P.; Kim, Cecilia E.; Klopp, Norman; Lahti, Jari; Lye, Stephen J.; McMahon, George; Mentch, Frank D.; Mueller-Nurasyid, Martina; O'Reilly, Paul F.; Prokopenko, Inga; Rivadeneira, Fernando; Steegers, Eric A. P.; Sunyer, Jordi; Tiesler, Carla; Yaghootkar, Hanieh; Breteler, Monique M. B.; Debette, Stephanie; Fornage, Myriam; Gudnason, Vilmundur; Launer, Lenore J.; van der Lugt, Aad; Mosley, Thomas H.; Seshadri, Sudha; Smith, Albert V.; Vernooij, Meike W.; Blakemore, Alexandra I. F.; Chiavacci, Rosetta M.; Feenstra, Bjarke; Fernandez-Banet, Julio; Grant, Struan F. A.; Hartikainen, Anna-Liisa; van der Heijden, Albert J.; Iniguez, Carmen; Lathrop, Mark; McArdle, Wendy L.; Molgaard, Anne; Newnham, John P.; Palmer, Lyle J.; Palotie, Aarno; Pouta, Annneli; Ring, Susan M.; Sovio, Ulla; Standl, Marie; Uitterlinden, Andre G.; Wichmann, H-Erich; Vissing, Nadja Hawwa; DeCarli, Charles; van Duijn, Cornelia M.; McCarthy, Mark I.; Koppelman, Gerard H.; Estivill, Xavier; Hattersley, Andrew T.; Melbye, Mads; Bisgaard, Hans; Pennell, Craig E.; Widen, Elisabeth; Hakonarson, Hakon; Smith, George Davey; Heinrich, Joachim; Jarvelin, Marjo-Riitta; Jaddoe, Vincent W. V.; Adair, Linda S.; Ang, Wei; Atalay, Mustafa; van Beijsterveldt, Toos; Bergen, Nienke; Benke, Kelly; Berry, Diane; Bradfield, Jonathan P.; Charoen, Pimphen; Coin, Lachlan; Cousminer, Diana L.; Das, Shikta; Davis, Oliver S. P.; Elliott, Paul; Evans, David M.; Feenstra, Bjarke; Flexeder, Claudia; Frayling, Tim; Freathy, Rachel M.; Gaillard, Romy; Geller, Frank; Groen-Blokhuis, Maria; Goh, Liang-Kee; Guxens, Monica; Haworth, Claire M. A.; Hadley, Dexter; Hedebrand, Johannes; Hinney, Anke; Hirschhorn, Joel N.; Holloway, John W.; Holst, Claus; Hottenga, Jouke Jan; Horikoshi, Momoko; Huikari, Ville; Hypponen, Elina; Iniguez, Carmen; Kaakinen, Marika; Kilpelainen, Tuomas O.; Kirin, Mirna; Kowgier, Matthew; Lakka, Hanna-Maaria; Lange, Leslie A.; Lawlor, Debbie A.; Lehtimaki, Terho; Lewin, Alex; Lindgren, Cecilia; Lindi, Virpi; Maggi, Reedik; Marsh, Julie; Middeldorp, Christel; Millwood, Iona; Mook-Kanamori, Dennis O.; Murray, Jeffrey C.; Nivard, Michel; Nohr, Ellen Aagaard; Ntalla, Ioanna; Oken, Emily; O'Reilly, Paul F.; Palmer, Lyle J.; Panoutsopoulou, Kalliope; Pararajasingham, Jennifer; Prokopenko, Inga; Rodriguez, Alina; Salem, Rany M.; Sebert, Sylvain; Siitonen, Niina; Sovio, Ulla; St Pourcain, Beate; Strachan, David P.; Sunyer, Jordi; Taal, H. Rob; Teo, Yik-Ying; Thiering, Elisabeth; Tiesler, Carla; Uitterlinden, Andre G.; Valcarcel, Beatriz; Warrington, Nicole M.; White, Scott; Willemsen, Gonneke; Yaghootkar, Hanieh; Zeggini, Eleftheria; Boomsma, Dorret I.; Cooper, Cyrus; Estivill, Xavier; Gillman, Matthew; Grant, Struan F. A.; Hakonarson, Hakon; Hattersley, Andrew T.; Heinrich, Joachim; Hocher, Berthold; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; Lakka, Timo A.; McCarthy, Mark I.; Melbye, Mads; Mohlke, Karen L.; Dedoussis, George V.; Ong, Ken K.; Pearson, Ewan R.; Pennell, Craig E.; Price, Thomas S.; Power, Chris; Raitakari, Olli T.; Saw, Seang-Mei; Scherag, Andre; Simell, Olli; Sorensen, Thorkild I. A.; Timpson, Nicholas J.; Widen, Elisabeth; Wilson, James F.; Ang, Wei; van Beijsterveldt, Toos; Bergen, Nienke; Benke, Kelly; Berry, Diane; Bradfield, Jonathan P.; Charoen, Pimphen; Coin, Lachlan; Cousminer, Diana L.; Das, Shikta; Elliott, Paul; Evans, David M.; Frayling, Tim; Freathy, Rachel M.; Gaillard, Romy; Groen-Blokhuis, Maria; Guxens, Monica; Hadley, Dexter; Hottenga, Jouke Jan; Huikari, Ville; Hypponen, Elina; Kaakinen, Marika; Kowgier, Matthew; Lawlor, Debbie A.; Lewin, Alex; Lindgren, Cecilia; Marsh, Julie; Middeldorp, Christel; Millwood, Iona; Mook-Kanamori, Dennis O.; Nivard, Michel; O'Reilly, Paul F.; Palmer, Lyle J.; Prokopenko, Inga; Rodriguez, Alina; Sebert, Sylvain; Sovio, Ulla; St Pourcain, Beate; Standl, Marie; Strachan, David P.; Sunyer, Jordi; Taal, H. Rob; Thiering, Elisabeth; Tiesler, Carla; Uitterlinden, Andre G.; Valcarcel, Beatriz; Warrington, Nicole M.; White, Scott; Willemsen, Gonneke; Yaghootkar, Hanieh; Boomsma, Dorret I.; Estivill, Xavier; Grant, Struan F. A.; Hakonarson, Hakon; Hattersley, Andrew T.; Heinrich, Joachim; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; McCarthy, Mark I.; Pennell, Craig E.; Power, Chris; Timpson, Nicholas J.; Widen, Elisabeth; Ikram, M. Arfan; Fornage, Myriam; Smith, Albert V.; Seshadri, Sudha; Schmidt, Reinhold; Debette, Stephanie; Vrooman, Henri A.; Sigurdsson, Sigurdur; Ropele, Stefan; Coker, Laura H.; Longstreth, W. T.; Niessen, Wiro J.; DeStefano, Anita L.; Beiser, Alexa; Zijdenbos, Alex P.; Struchalin, Maksim; Jack, Clifford R.; Nalls, Mike A.; Au, Rhoda; Hofman, Albert; Gudnason, Haukur; van der Lugt, Aad; Harris, Tamara B.; Meeks, William M.; Vernooij, Meike W.; van Buchem, Mark A.; Catellier, Diane; Gudnason, Vilmundur; Windham, B. Gwen; Wolf, Philip A.; van Duijn, Cornelia M.; Mosley, Thomas H.; Schmidt, Helena; Launer, Lenore J.; Breteler, Monique M. B.; DeCarli, Charles; Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep.

In: Nature Genetics, Vol. 44, No. 5, 05.2012, p. 532-538.

Research output: Contribution to journalArticle

Harvard

Taal, HR, St Pourcain, B, Thiering, E, Das, S, Mook-Kanamori, DO, Warrington, NM, Kaakinen, M, Kreiner-Moller, E, Bradfield, JP, Freathy, RM, Geller, F, Guxens, M, Cousminer, DL, Kerkhof, M, Timpson, NJ, Ikram, MA, Beilin, LJ, Bonnelykke, K, Buxton, JL, Charoen, P, Chawes, BLK, Eriksson, J, Evans, DM, Hofman, A, Kemp, JP, Kim, CE, Klopp, N, Lahti, J, Lye, SJ, McMahon, G, Mentch, FD, Mueller-Nurasyid, M, O'Reilly, PF, Prokopenko, I, Rivadeneira, F, Steegers, EAP, Sunyer, J, Tiesler, C, Yaghootkar, H, Breteler, MMB, Debette, S, Fornage, M, Gudnason, V, Launer, LJ, van der Lugt, A, Mosley, TH, Seshadri, S, Smith, AV, Vernooij, MW, Blakemore, AIF, Chiavacci, RM, Feenstra, B, Fernandez-Banet, J, Grant, SFA, Hartikainen, A-L, van der Heijden, AJ, Iniguez, C, Lathrop, M, McArdle, WL, Molgaard, A, Newnham, JP, Palmer, LJ, Palotie, A, Pouta, A, Ring, SM, Sovio, U, Standl, M, Uitterlinden, AG, Wichmann, H-E, Vissing, NH, DeCarli, C, van Duijn, CM, McCarthy, MI, Koppelman, GH, Estivill, X, Hattersley, AT, Melbye, M, Bisgaard, H, Pennell, CE, Widen, E, Hakonarson, H, Smith, GD, Heinrich, J, Jarvelin, M-R, Jaddoe, VWV, Adair, LS, Ang, W, Atalay, M, van Beijsterveldt, T, Bergen, N, Benke, K, Berry, D, Bradfield, JP, Charoen, P, Coin, L, Cousminer, DL, Das, S, Davis, OSP, Elliott, P, Evans, DM, Feenstra, B, Flexeder, C, Frayling, T, Freathy, RM, Gaillard, R, Geller, F, Groen-Blokhuis, M, Goh, L-K, Guxens, M, Haworth, CMA, Hadley, D, Hedebrand, J, Hinney, A, Hirschhorn, JN, Holloway, JW, Holst, C, Hottenga, JJ, Horikoshi, M, Huikari, V, Hypponen, E, Iniguez, C, Kaakinen, M, Kilpelainen, TO, Kirin, M, Kowgier, M, Lakka, H-M, Lange, LA, Lawlor, DA, Lehtimaki, T, Lewin, A, Lindgren, C, Lindi, V, Maggi, R, Marsh, J, Middeldorp, C, Millwood, I, Mook-Kanamori, DO, Murray, JC, Nivard, M, Nohr, EA, Ntalla, I, Oken, E, O'Reilly, PF, Palmer, LJ, Panoutsopoulou, K, Pararajasingham, J, Prokopenko, I, Rodriguez, A, Salem, RM, Sebert, S, Siitonen, N, Sovio, U, St Pourcain, B, Strachan, DP, Sunyer, J, Taal, HR, Teo, Y-Y, Thiering, E, Tiesler, C, Uitterlinden, AG, Valcarcel, B, Warrington, NM, White, S, Willemsen, G, Yaghootkar, H, Zeggini, E, Boomsma, DI, Cooper, C, Estivill, X, Gillman, M, Grant, SFA, Hakonarson, H, Hattersley, AT, Heinrich, J, Hocher, B, Jaddoe, VWV, Jarvelin, M-R, Lakka, TA, McCarthy, MI, Melbye, M, Mohlke, KL, Dedoussis, GV, Ong, KK, Pearson, ER, Pennell, CE, Price, TS, Power, C, Raitakari, OT, Saw, S-M, Scherag, A, Simell, O, Sorensen, TIA, Timpson, NJ, Widen, E, Wilson, JF, Ang, W, van Beijsterveldt, T, Bergen, N, Benke, K, Berry, D, Bradfield, JP, Charoen, P, Coin, L, Cousminer, DL, Das, S, Elliott, P, Evans, DM, Frayling, T, Freathy, RM, Gaillard, R, Groen-Blokhuis, M, Guxens, M, Hadley, D, Hottenga, JJ, Huikari, V, Hypponen, E, Kaakinen, M, Kowgier, M, Lawlor, DA, Lewin, A, Lindgren, C, Marsh, J, Middeldorp, C, Millwood, I, Mook-Kanamori, DO, Nivard, M, O'Reilly, PF, Palmer, LJ, Prokopenko, I, Rodriguez, A, Sebert, S, Sovio, U, St Pourcain, B, Standl, M, Strachan, DP, Sunyer, J, Taal, HR, Thiering, E, Tiesler, C, Uitterlinden, AG, Valcarcel, B, Warrington, NM, White, S, Willemsen, G, Yaghootkar, H, Boomsma, DI, Estivill, X, Grant, SFA, Hakonarson, H, Hattersley, AT, Heinrich, J, Jaddoe, VWV, Jarvelin, M-R, McCarthy, MI, Pennell, CE, Power, C, Timpson, NJ, Widen, E, Ikram, MA, Fornage, M, Smith, AV, Seshadri, S, Schmidt, R, Debette, S, Vrooman, HA, Sigurdsson, S, Ropele, S, Coker, LH, Longstreth, WT, Niessen, WJ, DeStefano, AL, Beiser, A, Zijdenbos, AP, Struchalin, M, Jack, CR, Nalls, MA, Au, R, Hofman, A, Gudnason, H, van der Lugt, A, Harris, TB, Meeks, WM, Vernooij, MW, van Buchem, MA, Catellier, D, Gudnason, V, Windham, BG, Wolf, PA, van Duijn, CM, Mosley, TH, Schmidt, H, Launer, LJ, Breteler, MMB, DeCarli, C & Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep 2012, 'Common variants at 12q15 and 12q24 are associated with infant head circumference' Nature Genetics, vol 44, no. 5, pp. 532-538., 10.1038/ng.2238

APA

Taal, H. R., St Pourcain, B., Thiering, E., Das, S., Mook-Kanamori, D. O., Warrington, N. M., ... Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep (2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics, 44(5), 532-538. 10.1038/ng.2238

Vancouver

Taal HR, St Pourcain B, Thiering E, Das S, Mook-Kanamori DO, Warrington NM et al. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nature Genetics. 2012 May;44(5):532-538. Available from: 10.1038/ng.2238

Author

Taal, H. Rob; St Pourcain, Beate; Thiering, Elisabeth; Das, Shikta; Mook-Kanamori, Dennis O.; Warrington, Nicole M.; Kaakinen, Marika; Kreiner-Moller, Eskil; Bradfield, Jonathan P.; Freathy, Rachel M.; Geller, Frank; Guxens, Monica; Cousminer, Diana L.; Kerkhof, Marjan; Timpson, Nicholas J.; Ikram, M. Arfan; Beilin, Lawrence J.; Bonnelykke, Klaus; Buxton, Jessica L.; Charoen, Pimphen; Chawes, Bo Lund Krogsgaard; Eriksson, Johan; Evans, David M.; Hofman, Albert; Kemp, John P.; Kim, Cecilia E.; Klopp, Norman; Lahti, Jari; Lye, Stephen J.; McMahon, George; Mentch, Frank D.; Mueller-Nurasyid, Martina; O'Reilly, Paul F.; Prokopenko, Inga; Rivadeneira, Fernando; Steegers, Eric A. P.; Sunyer, Jordi; Tiesler, Carla; Yaghootkar, Hanieh; Breteler, Monique M. B.; Debette, Stephanie; Fornage, Myriam; Gudnason, Vilmundur; Launer, Lenore J.; van der Lugt, Aad; Mosley, Thomas H.; Seshadri, Sudha; Smith, Albert V.; Vernooij, Meike W.; Blakemore, Alexandra I. F.; Chiavacci, Rosetta M.; Feenstra, Bjarke; Fernandez-Banet, Julio; Grant, Struan F. A.; Hartikainen, Anna-Liisa; van der Heijden, Albert J.; Iniguez, Carmen; Lathrop, Mark; McArdle, Wendy L.; Molgaard, Anne; Newnham, John P.; Palmer, Lyle J.; Palotie, Aarno; Pouta, Annneli; Ring, Susan M.; Sovio, Ulla; Standl, Marie; Uitterlinden, Andre G.; Wichmann, H-Erich; Vissing, Nadja Hawwa; DeCarli, Charles; van Duijn, Cornelia M.; McCarthy, Mark I.; Koppelman, Gerard H.; Estivill, Xavier; Hattersley, Andrew T.; Melbye, Mads; Bisgaard, Hans; Pennell, Craig E.; Widen, Elisabeth; Hakonarson, Hakon; Smith, George Davey; Heinrich, Joachim; Jarvelin, Marjo-Riitta; Jaddoe, Vincent W. V.; Adair, Linda S.; Ang, Wei; Atalay, Mustafa; van Beijsterveldt, Toos; Bergen, Nienke; Benke, Kelly; Berry, Diane; Bradfield, Jonathan P.; Charoen, Pimphen; Coin, Lachlan; Cousminer, Diana L.; Das, Shikta; Davis, Oliver S. P.; Elliott, Paul; Evans, David M.; Feenstra, Bjarke; Flexeder, Claudia; Frayling, Tim; Freathy, Rachel M.; Gaillard, Romy; Geller, Frank; Groen-Blokhuis, Maria; Goh, Liang-Kee; Guxens, Monica; Haworth, Claire M. A.; Hadley, Dexter; Hedebrand, Johannes; Hinney, Anke; Hirschhorn, Joel N.; Holloway, John W.; Holst, Claus; Hottenga, Jouke Jan; Horikoshi, Momoko; Huikari, Ville; Hypponen, Elina; Iniguez, Carmen; Kaakinen, Marika; Kilpelainen, Tuomas O.; Kirin, Mirna; Kowgier, Matthew; Lakka, Hanna-Maaria; Lange, Leslie A.; Lawlor, Debbie A.; Lehtimaki, Terho; Lewin, Alex; Lindgren, Cecilia; Lindi, Virpi; Maggi, Reedik; Marsh, Julie; Middeldorp, Christel; Millwood, Iona; Mook-Kanamori, Dennis O.; Murray, Jeffrey C.; Nivard, Michel; Nohr, Ellen Aagaard; Ntalla, Ioanna; Oken, Emily; O'Reilly, Paul F.; Palmer, Lyle J.; Panoutsopoulou, Kalliope; Pararajasingham, Jennifer; Prokopenko, Inga; Rodriguez, Alina; Salem, Rany M.; Sebert, Sylvain; Siitonen, Niina; Sovio, Ulla; St Pourcain, Beate; Strachan, David P.; Sunyer, Jordi; Taal, H. Rob; Teo, Yik-Ying; Thiering, Elisabeth; Tiesler, Carla; Uitterlinden, Andre G.; Valcarcel, Beatriz; Warrington, Nicole M.; White, Scott; Willemsen, Gonneke; Yaghootkar, Hanieh; Zeggini, Eleftheria; Boomsma, Dorret I.; Cooper, Cyrus; Estivill, Xavier; Gillman, Matthew; Grant, Struan F. A.; Hakonarson, Hakon; Hattersley, Andrew T.; Heinrich, Joachim; Hocher, Berthold; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; Lakka, Timo A.; McCarthy, Mark I.; Melbye, Mads; Mohlke, Karen L.; Dedoussis, George V.; Ong, Ken K.; Pearson, Ewan R.; Pennell, Craig E.; Price, Thomas S.; Power, Chris; Raitakari, Olli T.; Saw, Seang-Mei; Scherag, Andre; Simell, Olli; Sorensen, Thorkild I. A.; Timpson, Nicholas J.; Widen, Elisabeth; Wilson, James F.; Ang, Wei; van Beijsterveldt, Toos; Bergen, Nienke; Benke, Kelly; Berry, Diane; Bradfield, Jonathan P.; Charoen, Pimphen; Coin, Lachlan; Cousminer, Diana L.; Das, Shikta; Elliott, Paul; Evans, David M.; Frayling, Tim; Freathy, Rachel M.; Gaillard, Romy; Groen-Blokhuis, Maria; Guxens, Monica; Hadley, Dexter; Hottenga, Jouke Jan; Huikari, Ville; Hypponen, Elina; Kaakinen, Marika; Kowgier, Matthew; Lawlor, Debbie A.; Lewin, Alex; Lindgren, Cecilia; Marsh, Julie; Middeldorp, Christel; Millwood, Iona; Mook-Kanamori, Dennis O.; Nivard, Michel; O'Reilly, Paul F.; Palmer, Lyle J.; Prokopenko, Inga; Rodriguez, Alina; Sebert, Sylvain; Sovio, Ulla; St Pourcain, Beate; Standl, Marie; Strachan, David P.; Sunyer, Jordi; Taal, H. Rob; Thiering, Elisabeth; Tiesler, Carla; Uitterlinden, Andre G.; Valcarcel, Beatriz; Warrington, Nicole M.; White, Scott; Willemsen, Gonneke; Yaghootkar, Hanieh; Boomsma, Dorret I.; Estivill, Xavier; Grant, Struan F. A.; Hakonarson, Hakon; Hattersley, Andrew T.; Heinrich, Joachim; Jaddoe, Vincent W. V.; Jarvelin, Marjo-Riitta; McCarthy, Mark I.; Pennell, Craig E.; Power, Chris; Timpson, Nicholas J.; Widen, Elisabeth; Ikram, M. Arfan; Fornage, Myriam; Smith, Albert V.; Seshadri, Sudha; Schmidt, Reinhold; Debette, Stephanie; Vrooman, Henri A.; Sigurdsson, Sigurdur; Ropele, Stefan; Coker, Laura H.; Longstreth, W. T.; Niessen, Wiro J.; DeStefano, Anita L.; Beiser, Alexa; Zijdenbos, Alex P.; Struchalin, Maksim; Jack, Clifford R.; Nalls, Mike A.; Au, Rhoda; Hofman, Albert; Gudnason, Haukur; van der Lugt, Aad; Harris, Tamara B.; Meeks, William M.; Vernooij, Meike W.; van Buchem, Mark A.; Catellier, Diane; Gudnason, Vilmundur; Windham, B. Gwen; Wolf, Philip A.; van Duijn, Cornelia M.; Mosley, Thomas H.; Schmidt, Helena; Launer, Lenore J.; Breteler, Monique M. B.; DeCarli, Charles; Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep / Common variants at 12q15 and 12q24 are associated with infant head circumference.

In: Nature Genetics, Vol. 44, No. 5, 05.2012, p. 532-538.

Research output: Contribution to journalArticle

Bibtex - Download

@article{32fc509c7cb5482ab743fff7b6c2f253,
title = "Common variants at 12q15 and 12q24 are associated with infant head circumference",
author = "Taal, {H. Rob} and {St Pourcain}, Beate and Elisabeth Thiering and Shikta Das and Mook-Kanamori, {Dennis O.} and Warrington, {Nicole M.} and Marika Kaakinen and Eskil Kreiner-Moller and Bradfield, {Jonathan P.} and Freathy, {Rachel M.} and Frank Geller and Monica Guxens and Cousminer, {Diana L.} and Marjan Kerkhof and Timpson, {Nicholas J.} and Ikram, {M. Arfan} and Beilin, {Lawrence J.} and Klaus Bonnelykke and Buxton, {Jessica L.} and Pimphen Charoen and Chawes, {Bo Lund Krogsgaard} and Johan Eriksson and Evans, {David M.} and Albert Hofman and Kemp, {John P.} and Kim, {Cecilia E.} and Norman Klopp and Jari Lahti and Lye, {Stephen J.} and George McMahon and Mentch, {Frank D.} and Martina Mueller-Nurasyid and O'Reilly, {Paul F.} and Inga Prokopenko and Fernando Rivadeneira and Steegers, {Eric A. P.} and Jordi Sunyer and Carla Tiesler and Hanieh Yaghootkar and Breteler, {Monique M. B.} and Stephanie Debette and Myriam Fornage and Vilmundur Gudnason and Launer, {Lenore J.} and {van der Lugt}, Aad and Mosley, {Thomas H.} and Sudha Seshadri and Smith, {Albert V.} and Vernooij, {Meike W.} and Blakemore, {Alexandra I. F.} and Chiavacci, {Rosetta M.} and Bjarke Feenstra and Julio Fernandez-Banet and Grant, {Struan F. A.} and Anna-Liisa Hartikainen and {van der Heijden}, {Albert J.} and Carmen Iniguez and Mark Lathrop and McArdle, {Wendy L.} and Anne Molgaard and Newnham, {John P.} and Palmer, {Lyle J.} and Aarno Palotie and Annneli Pouta and Ring, {Susan M.} and Ulla Sovio and Marie Standl and Uitterlinden, {Andre G.} and H-Erich Wichmann and Vissing, {Nadja Hawwa} and Charles DeCarli and {van Duijn}, {Cornelia M.} and McCarthy, {Mark I.} and Koppelman, {Gerard H.} and Xavier Estivill and Hattersley, {Andrew T.} and Mads Melbye and Hans Bisgaard and Pennell, {Craig E.} and Elisabeth Widen and Hakon Hakonarson and Smith, {George Davey} and Joachim Heinrich and Marjo-Riitta Jarvelin and Jaddoe, {Vincent W. V.} and Adair, {Linda S.} and Wei Ang and Mustafa Atalay and {van Beijsterveldt}, Toos and Nienke Bergen and Kelly Benke and Diane Berry and Bradfield, {Jonathan P.} and Pimphen Charoen and Lachlan Coin and Cousminer, {Diana L.} and Shikta Das and Davis, {Oliver S. P.} and Paul Elliott and Evans, {David M.} and Bjarke Feenstra and Claudia Flexeder and Tim Frayling and Freathy, {Rachel M.} and Romy Gaillard and Frank Geller and Maria Groen-Blokhuis and Liang-Kee Goh and Monica Guxens and Haworth, {Claire M. A.} and Dexter Hadley and Johannes Hedebrand and Anke Hinney and Hirschhorn, {Joel N.} and Holloway, {John W.} and Claus Holst and Hottenga, {Jouke Jan} and Momoko Horikoshi and Ville Huikari and Elina Hypponen and Carmen Iniguez and Marika Kaakinen and Kilpelainen, {Tuomas O.} and Mirna Kirin and Matthew Kowgier and Hanna-Maaria Lakka and Lange, {Leslie A.} and Lawlor, {Debbie A.} and Terho Lehtimaki and Alex Lewin and Cecilia Lindgren and Virpi Lindi and Reedik Maggi and Julie Marsh and Christel Middeldorp and Iona Millwood and Mook-Kanamori, {Dennis O.} and Murray, {Jeffrey C.} and Michel Nivard and Nohr, {Ellen Aagaard} and Ioanna Ntalla and Emily Oken and O'Reilly, {Paul F.} and Palmer, {Lyle J.} and Kalliope Panoutsopoulou and Jennifer Pararajasingham and Inga Prokopenko and Alina Rodriguez and Salem, {Rany M.} and Sylvain Sebert and Niina Siitonen and Ulla Sovio and {St Pourcain}, Beate and Strachan, {David P.} and Jordi Sunyer and Taal, {H. Rob} and Yik-Ying Teo and Elisabeth Thiering and Carla Tiesler and Uitterlinden, {Andre G.} and Beatriz Valcarcel and Warrington, {Nicole M.} and Scott White and Gonneke Willemsen and Hanieh Yaghootkar and Eleftheria Zeggini and Boomsma, {Dorret I.} and Cyrus Cooper and Xavier Estivill and Matthew Gillman and Grant, {Struan F. A.} and Hakon Hakonarson and Hattersley, {Andrew T.} and Joachim Heinrich and Berthold Hocher and Jaddoe, {Vincent W. V.} and Marjo-Riitta Jarvelin and Lakka, {Timo A.} and McCarthy, {Mark I.} and Mads Melbye and Mohlke, {Karen L.} and Dedoussis, {George V.} and Ong, {Ken K.} and Pearson, {Ewan R.} and Pennell, {Craig E.} and Price, {Thomas S.} and Chris Power and Raitakari, {Olli T.} and Seang-Mei Saw and Andre Scherag and Olli Simell and Sorensen, {Thorkild I. A.} and Timpson, {Nicholas J.} and Elisabeth Widen and Wilson, {James F.} and Wei Ang and {van Beijsterveldt}, Toos and Nienke Bergen and Kelly Benke and Diane Berry and Bradfield, {Jonathan P.} and Pimphen Charoen and Lachlan Coin and Cousminer, {Diana L.} and Shikta Das and Paul Elliott and Evans, {David M.} and Tim Frayling and Freathy, {Rachel M.} and Romy Gaillard and Maria Groen-Blokhuis and Monica Guxens and Dexter Hadley and Hottenga, {Jouke Jan} and Ville Huikari and Elina Hypponen and Marika Kaakinen and Matthew Kowgier and Lawlor, {Debbie A.} and Alex Lewin and Cecilia Lindgren and Julie Marsh and Christel Middeldorp and Iona Millwood and Mook-Kanamori, {Dennis O.} and Michel Nivard and O'Reilly, {Paul F.} and Palmer, {Lyle J.} and Inga Prokopenko and Alina Rodriguez and Sylvain Sebert and Ulla Sovio and {St Pourcain}, Beate and Marie Standl and Strachan, {David P.} and Jordi Sunyer and Taal, {H. Rob} and Elisabeth Thiering and Carla Tiesler and Uitterlinden, {Andre G.} and Beatriz Valcarcel and Warrington, {Nicole M.} and Scott White and Gonneke Willemsen and Hanieh Yaghootkar and Boomsma, {Dorret I.} and Xavier Estivill and Grant, {Struan F. A.} and Hakon Hakonarson and Hattersley, {Andrew T.} and Joachim Heinrich and Jaddoe, {Vincent W. V.} and Marjo-Riitta Jarvelin and McCarthy, {Mark I.} and Pennell, {Craig E.} and Chris Power and Timpson, {Nicholas J.} and Elisabeth Widen and Ikram, {M. Arfan} and Myriam Fornage and Smith, {Albert V.} and Sudha Seshadri and Reinhold Schmidt and Stephanie Debette and Vrooman, {Henri A.} and Sigurdur Sigurdsson and Stefan Ropele and Coker, {Laura H.} and Longstreth, {W. T.} and Niessen, {Wiro J.} and DeStefano, {Anita L.} and Alexa Beiser and Zijdenbos, {Alex P.} and Maksim Struchalin and Jack, {Clifford R.} and Nalls, {Mike A.} and Rhoda Au and Albert Hofman and Haukur Gudnason and {van der Lugt}, Aad and Harris, {Tamara B.} and Meeks, {William M.} and Vernooij, {Meike W.} and {van Buchem}, {Mark A.} and Diane Catellier and Vilmundur Gudnason and Windham, {B. Gwen} and Wolf, {Philip A.} and {van Duijn}, {Cornelia M.} and Mosley, {Thomas H.} and Helena Schmidt and Launer, {Lenore J.} and Breteler, {Monique M. B.} and Charles DeCarli and {Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep}",
year = "2012",
doi = "10.1038/ng.2238",
volume = "44",
number = "5",
pages = "532--538",
journal = "Nature Genetics",
issn = "1061-4036",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Common variants at 12q15 and 12q24 are associated with infant head circumference

A1 - Taal,H. Rob

A1 - St Pourcain,Beate

A1 - Thiering,Elisabeth

A1 - Das,Shikta

A1 - Mook-Kanamori,Dennis O.

A1 - Warrington,Nicole M.

A1 - Kaakinen,Marika

A1 - Kreiner-Moller,Eskil

A1 - Bradfield,Jonathan P.

A1 - Freathy,Rachel M.

A1 - Geller,Frank

A1 - Guxens,Monica

A1 - Cousminer,Diana L.

A1 - Kerkhof,Marjan

A1 - Timpson,Nicholas J.

A1 - Ikram,M. Arfan

A1 - Beilin,Lawrence J.

A1 - Bonnelykke,Klaus

A1 - Buxton,Jessica L.

A1 - Charoen,Pimphen

A1 - Chawes,Bo Lund Krogsgaard

A1 - Eriksson,Johan

A1 - Evans,David M.

A1 - Hofman,Albert

A1 - Kemp,John P.

A1 - Kim,Cecilia E.

A1 - Klopp,Norman

A1 - Lahti,Jari

A1 - Lye,Stephen J.

A1 - McMahon,George

A1 - Mentch,Frank D.

A1 - Mueller-Nurasyid,Martina

A1 - O'Reilly,Paul F.

A1 - Prokopenko,Inga

A1 - Rivadeneira,Fernando

A1 - Steegers,Eric A. P.

A1 - Sunyer,Jordi

A1 - Tiesler,Carla

A1 - Yaghootkar,Hanieh

A1 - Breteler,Monique M. B.

A1 - Debette,Stephanie

A1 - Fornage,Myriam

A1 - Gudnason,Vilmundur

A1 - Launer,Lenore J.

A1 - van der Lugt,Aad

A1 - Mosley,Thomas H.

A1 - Seshadri,Sudha

A1 - Smith,Albert V.

A1 - Vernooij,Meike W.

A1 - Blakemore,Alexandra I. F.

A1 - Chiavacci,Rosetta M.

A1 - Feenstra,Bjarke

A1 - Fernandez-Banet,Julio

A1 - Grant,Struan F. A.

A1 - Hartikainen,Anna-Liisa

A1 - van der Heijden,Albert J.

A1 - Iniguez,Carmen

A1 - Lathrop,Mark

A1 - McArdle,Wendy L.

A1 - Molgaard,Anne

A1 - Newnham,John P.

A1 - Palmer,Lyle J.

A1 - Palotie,Aarno

A1 - Pouta,Annneli

A1 - Ring,Susan M.

A1 - Sovio,Ulla

A1 - Standl,Marie

A1 - Uitterlinden,Andre G.

A1 - Wichmann,H-Erich

A1 - Vissing,Nadja Hawwa

A1 - DeCarli,Charles

A1 - van Duijn,Cornelia M.

A1 - McCarthy,Mark I.

A1 - Koppelman,Gerard H.

A1 - Estivill,Xavier

A1 - Hattersley,Andrew T.

A1 - Melbye,Mads

A1 - Bisgaard,Hans

A1 - Pennell,Craig E.

A1 - Widen,Elisabeth

A1 - Hakonarson,Hakon

A1 - Smith,George Davey

A1 - Heinrich,Joachim

A1 - Jarvelin,Marjo-Riitta

A1 - Jaddoe,Vincent W. V.

A1 - Adair,Linda S.

A1 - Ang,Wei

A1 - Atalay,Mustafa

A1 - van Beijsterveldt,Toos

A1 - Bergen,Nienke

A1 - Benke,Kelly

A1 - Berry,Diane

A1 - Coin,Lachlan

A1 - Davis,Oliver S. P.

A1 - Elliott,Paul

A1 - Flexeder,Claudia

A1 - Frayling,Tim

A1 - Gaillard,Romy

A1 - Groen-Blokhuis,Maria

A1 - Goh,Liang-Kee

A1 - Haworth,Claire M. A.

A1 - Hadley,Dexter

A1 - Hedebrand,Johannes

A1 - Hinney,Anke

A1 - Hirschhorn,Joel N.

A1 - Holloway,John W.

A1 - Holst,Claus

A1 - Hottenga,Jouke Jan

A1 - Horikoshi,Momoko

A1 - Huikari,Ville

A1 - Hypponen,Elina

A1 - Kilpelainen,Tuomas O.

A1 - Kirin,Mirna

A1 - Kowgier,Matthew

A1 - Lakka,Hanna-Maaria

A1 - Lange,Leslie A.

A1 - Lawlor,Debbie A.

A1 - Lehtimaki,Terho

A1 - Lewin,Alex

A1 - Lindgren,Cecilia

A1 - Lindi,Virpi

A1 - Maggi,Reedik

A1 - Marsh,Julie

A1 - Middeldorp,Christel

A1 - Millwood,Iona

A1 - Murray,Jeffrey C.

A1 - Nivard,Michel

A1 - Nohr,Ellen Aagaard

A1 - Ntalla,Ioanna

A1 - Oken,Emily

A1 - Panoutsopoulou,Kalliope

A1 - Pararajasingham,Jennifer

A1 - Rodriguez,Alina

A1 - Salem,Rany M.

A1 - Sebert,Sylvain

A1 - Siitonen,Niina

A1 - Strachan,David P.

A1 - Teo,Yik-Ying

A1 - Valcarcel,Beatriz

A1 - White,Scott

A1 - Willemsen,Gonneke

A1 - Zeggini,Eleftheria

A1 - Boomsma,Dorret I.

A1 - Cooper,Cyrus

A1 - Gillman,Matthew

A1 - Hocher,Berthold

A1 - Lakka,Timo A.

A1 - Mohlke,Karen L.

A1 - Dedoussis,George V.

A1 - Ong,Ken K.

A1 - Pearson,Ewan R.

A1 - Price,Thomas S.

A1 - Power,Chris

A1 - Raitakari,Olli T.

A1 - Saw,Seang-Mei

A1 - Scherag,Andre

A1 - Simell,Olli

A1 - Sorensen,Thorkild I. A.

A1 - Wilson,James F.

A1 - Schmidt,Reinhold

A1 - Vrooman,Henri A.

A1 - Sigurdsson,Sigurdur

A1 - Ropele,Stefan

A1 - Coker,Laura H.

A1 - Longstreth,W. T.

A1 - Niessen,Wiro J.

A1 - DeStefano,Anita L.

A1 - Beiser,Alexa

A1 - Zijdenbos,Alex P.

A1 - Struchalin,Maksim

A1 - Jack,Clifford R.

A1 - Nalls,Mike A.

A1 - Au,Rhoda

A1 - Gudnason,Haukur

A1 - Harris,Tamara B.

A1 - Meeks,William M.

A1 - van Buchem,Mark A.

A1 - Catellier,Diane

A1 - Windham,B. Gwen

A1 - Wolf,Philip A.

A1 - Schmidt,Helena

A1 - Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep

AU - Taal,H. Rob

AU - St Pourcain,Beate

AU - Thiering,Elisabeth

AU - Das,Shikta

AU - Mook-Kanamori,Dennis O.

AU - Warrington,Nicole M.

AU - Kaakinen,Marika

AU - Kreiner-Moller,Eskil

AU - Bradfield,Jonathan P.

AU - Freathy,Rachel M.

AU - Geller,Frank

AU - Guxens,Monica

AU - Cousminer,Diana L.

AU - Kerkhof,Marjan

AU - Timpson,Nicholas J.

AU - Ikram,M. Arfan

AU - Beilin,Lawrence J.

AU - Bonnelykke,Klaus

AU - Buxton,Jessica L.

AU - Charoen,Pimphen

AU - Chawes,Bo Lund Krogsgaard

AU - Eriksson,Johan

AU - Evans,David M.

AU - Hofman,Albert

AU - Kemp,John P.

AU - Kim,Cecilia E.

AU - Klopp,Norman

AU - Lahti,Jari

AU - Lye,Stephen J.

AU - McMahon,George

AU - Mentch,Frank D.

AU - Mueller-Nurasyid,Martina

AU - O'Reilly,Paul F.

AU - Prokopenko,Inga

AU - Rivadeneira,Fernando

AU - Steegers,Eric A. P.

AU - Sunyer,Jordi

AU - Tiesler,Carla

AU - Yaghootkar,Hanieh

AU - Breteler,Monique M. B.

AU - Debette,Stephanie

AU - Fornage,Myriam

AU - Gudnason,Vilmundur

AU - Launer,Lenore J.

AU - van der Lugt,Aad

AU - Mosley,Thomas H.

AU - Seshadri,Sudha

AU - Smith,Albert V.

AU - Vernooij,Meike W.

AU - Blakemore,Alexandra I. F.

AU - Chiavacci,Rosetta M.

AU - Feenstra,Bjarke

AU - Fernandez-Banet,Julio

AU - Grant,Struan F. A.

AU - Hartikainen,Anna-Liisa

AU - van der Heijden,Albert J.

AU - Iniguez,Carmen

AU - Lathrop,Mark

AU - McArdle,Wendy L.

AU - Molgaard,Anne

AU - Newnham,John P.

AU - Palmer,Lyle J.

AU - Palotie,Aarno

AU - Pouta,Annneli

AU - Ring,Susan M.

AU - Sovio,Ulla

AU - Standl,Marie

AU - Uitterlinden,Andre G.

AU - Wichmann,H-Erich

AU - Vissing,Nadja Hawwa

AU - DeCarli,Charles

AU - van Duijn,Cornelia M.

AU - McCarthy,Mark I.

AU - Koppelman,Gerard H.

AU - Estivill,Xavier

AU - Hattersley,Andrew T.

AU - Melbye,Mads

AU - Bisgaard,Hans

AU - Pennell,Craig E.

AU - Widen,Elisabeth

AU - Hakonarson,Hakon

AU - Smith,George Davey

AU - Heinrich,Joachim

AU - Jarvelin,Marjo-Riitta

AU - Jaddoe,Vincent W. V.

AU - Adair,Linda S.

AU - Ang,Wei

AU - Atalay,Mustafa

AU - van Beijsterveldt,Toos

AU - Bergen,Nienke

AU - Benke,Kelly

AU - Berry,Diane

AU - Coin,Lachlan

AU - Davis,Oliver S. P.

AU - Elliott,Paul

AU - Flexeder,Claudia

AU - Frayling,Tim

AU - Gaillard,Romy

AU - Groen-Blokhuis,Maria

AU - Goh,Liang-Kee

AU - Haworth,Claire M. A.

AU - Hadley,Dexter

AU - Hedebrand,Johannes

AU - Hinney,Anke

AU - Hirschhorn,Joel N.

AU - Holloway,John W.

AU - Holst,Claus

AU - Hottenga,Jouke Jan

AU - Horikoshi,Momoko

AU - Huikari,Ville

AU - Hypponen,Elina

AU - Kilpelainen,Tuomas O.

AU - Kirin,Mirna

AU - Kowgier,Matthew

AU - Lakka,Hanna-Maaria

AU - Lange,Leslie A.

AU - Lawlor,Debbie A.

AU - Lehtimaki,Terho

AU - Lewin,Alex

AU - Lindgren,Cecilia

AU - Lindi,Virpi

AU - Maggi,Reedik

AU - Marsh,Julie

AU - Middeldorp,Christel

AU - Millwood,Iona

AU - Murray,Jeffrey C.

AU - Nivard,Michel

AU - Nohr,Ellen Aagaard

AU - Ntalla,Ioanna

AU - Oken,Emily

AU - Panoutsopoulou,Kalliope

AU - Pararajasingham,Jennifer

AU - Rodriguez,Alina

AU - Salem,Rany M.

AU - Sebert,Sylvain

AU - Siitonen,Niina

AU - Strachan,David P.

AU - Teo,Yik-Ying

AU - Valcarcel,Beatriz

AU - White,Scott

AU - Willemsen,Gonneke

AU - Zeggini,Eleftheria

AU - Boomsma,Dorret I.

AU - Cooper,Cyrus

AU - Gillman,Matthew

AU - Hocher,Berthold

AU - Lakka,Timo A.

AU - Mohlke,Karen L.

AU - Dedoussis,George V.

AU - Ong,Ken K.

AU - Pearson,Ewan R.

AU - Price,Thomas S.

AU - Power,Chris

AU - Raitakari,Olli T.

AU - Saw,Seang-Mei

AU - Scherag,Andre

AU - Simell,Olli

AU - Sorensen,Thorkild I. A.

AU - Wilson,James F.

AU - Schmidt,Reinhold

AU - Vrooman,Henri A.

AU - Sigurdsson,Sigurdur

AU - Ropele,Stefan

AU - Coker,Laura H.

AU - Longstreth,W. T.

AU - Niessen,Wiro J.

AU - DeStefano,Anita L.

AU - Beiser,Alexa

AU - Zijdenbos,Alex P.

AU - Struchalin,Maksim

AU - Jack,Clifford R.

AU - Nalls,Mike A.

AU - Au,Rhoda

AU - Gudnason,Haukur

AU - Harris,Tamara B.

AU - Meeks,William M.

AU - van Buchem,Mark A.

AU - Catellier,Diane

AU - Windham,B. Gwen

AU - Wolf,Philip A.

AU - Schmidt,Helena

AU - Early Genetics Lifecourse Epidemio, Early Growth Genetics EGG Consorti, Cohorts Heart Aging Res Genetic Ep

PY - 2012/5

Y1 - 2012/5

N2 - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.</p>

AB - To identify genetic variants associated with head circumference in infancy, we performed a meta-analysis of seven genome-wide association studies (GWAS) (N = 10,768 individuals of European ancestry enrolled in pregnancy and/or birth cohorts) and followed up three lead signals in six replication studies (combined N = 19,089). rs7980687 on chromosome 12q24 (P = 8.1 x 10(-9)) and rs1042725 on chromosome 12q15 (P = 2.8 x 10(-10)) were robustly associated with head circumference in infancy. Although these loci have previously been associated with adult height(1), their effects on infant head circumference were largely independent of height (P = 3.8 x 10(-7) for rs7980687 and P = 1.3 x 10(-7) for rs1042725 after adjustment for infant height). A third signal, rs11655470 on chromosome 17q21, showed suggestive evidence of association with head circumference (P = 3.9 x 10(-6)). SNPs correlated to the 17q21 signal have shown genome-wide association with adult intracranial volume(2), Parkinson's disease and other neurodegenerative diseases(3-5), indicating that a common genetic variant in this region might link early brain growth with neurological disease in later life.</p>

U2 - 10.1038/ng.2238

DO - 10.1038/ng.2238

M1 - Article

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 5

VL - 44

SP - 532

EP - 538

ER -

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