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Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique

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Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique : a pilot study. / O'Dwyer, Martin; Day, Adam; Padgett, Miles; Ogden, G. R.; McLaren, S.; Goodman, Carol R.

In: British Journal of Oral and Maxillofacial Surgery, Vol. 46, No. 1, 01.2008, p. 6-10.

Research output: Contribution to journalArticle

Harvard

O'Dwyer, M, Day, A, Padgett, M, Ogden, GR, McLaren, S & Goodman, CR 2008, 'Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique: a pilot study' British Journal of Oral and Maxillofacial Surgery, vol 46, no. 1, pp. 6-10.

APA

O'Dwyer, M., Day, A., Padgett, M., Ogden, G. R., McLaren, S., & Goodman, C. R. (2008). Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique: a pilot study. British Journal of Oral and Maxillofacial Surgery, 46(1), 6-10doi: 10.1016/j.bjoms.2007.05.009

Vancouver

O'Dwyer M, Day A, Padgett M, Ogden GR, McLaren S, Goodman CR. Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique: a pilot study. British Journal of Oral and Maxillofacial Surgery. 2008 Jan;46(1):6-10.

Author

O'Dwyer, Martin; Day, Adam; Padgett, Miles; Ogden, G. R.; McLaren, S.; Goodman, Carol R. / Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique : a pilot study.

In: British Journal of Oral and Maxillofacial Surgery, Vol. 46, No. 1, 01.2008, p. 6-10.

Research output: Contribution to journalArticle

Bibtex - Download

@article{67964ef784bb45cab84e39effbcf71ca,
title = "Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique",
author = "Martin O'Dwyer and Adam Day and Miles Padgett and Ogden, {G. R.} and S. McLaren and Goodman, {Carol R.}",
year = "2008",
volume = "46",
number = "1",
pages = "6--10",
journal = "British Journal of Oral and Maxillofacial Surgery",
issn = "0266-4356",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Detection of mucosal abnormalities in patients with oral cancer using a photodynamic technique

T2 - a pilot study

A1 - O'Dwyer,Martin

A1 - Day,Adam

A1 - Padgett,Miles

A1 - Ogden,G. R.

A1 - McLaren,S.

A1 - Goodman,Carol R.

AU - O'Dwyer,Martin

AU - Day,Adam

AU - Padgett,Miles

AU - Ogden,G. R.

AU - McLaren,S.

AU - Goodman,Carol R.

PY - 2008/1

Y1 - 2008/1

N2 - <p>Patients who have had one oral cancer are at increased risk of developing a further malignant tumour, the detection of which is made difficult (and is often delayed) by the innocuous appearance of the early oral lesion. A technique that could reliably detect early cancers would be useful to both oral and dental health specialists. We describe a pilot study in which we used a compact spectroscopic instrument designed to excite and measure fluorescence in the oral cavity. The data were processed using principal components analysis, and the results suggest that the technique might be valuable for detecting early oral cancers. Further work should be performed to investigate some unusual characteristics observed within our data to ascertain if these are significant, simply due to errors made due data collection, or are due to other lifestyle factors. Such work could also verify that the data are due to detection of ALA metabolite in cancer and not some other systemic effect. (c) 2007 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.</p>

AB - <p>Patients who have had one oral cancer are at increased risk of developing a further malignant tumour, the detection of which is made difficult (and is often delayed) by the innocuous appearance of the early oral lesion. A technique that could reliably detect early cancers would be useful to both oral and dental health specialists. We describe a pilot study in which we used a compact spectroscopic instrument designed to excite and measure fluorescence in the oral cavity. The data were processed using principal components analysis, and the results suggest that the technique might be valuable for detecting early oral cancers. Further work should be performed to investigate some unusual characteristics observed within our data to ascertain if these are significant, simply due to errors made due data collection, or are due to other lifestyle factors. Such work could also verify that the data are due to detection of ALA metabolite in cancer and not some other systemic effect. (c) 2007 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.</p>

KW - Photodynamic detection

KW - Oral cancer

KW - Biopsy

U2 - 10.1016/j.bjoms.2007.05.009

DO - 10.1016/j.bjoms.2007.05.009

M1 - Article

JO - British Journal of Oral and Maxillofacial Surgery

JF - British Journal of Oral and Maxillofacial Surgery

SN - 0266-4356

IS - 1

VL - 46

SP - 6

EP - 10

ER -

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