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Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography

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Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography. / Li, Chunhui; Guan, Guangying; Reif, Roberto; Huang, Zhihong; Wang, Ruikang K.

In: Journal of the Royal Society Interface, Vol. 9, No. 70, 07.05.2012, p. 831-841.

Research output: Contribution to journalArticle

Harvard

Li, C, Guan, G, Reif, R, Huang, Z & Wang, RK 2012, 'Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography' Journal of the Royal Society Interface, vol 9, no. 70, pp. 831-841.

APA

Li, C., Guan, G., Reif, R., Huang, Z., & Wang, R. K. (2012). Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography. Journal of the Royal Society Interface, 9(70), 831-841doi: 10.1098/rsif.2011.0583

Vancouver

Li C, Guan G, Reif R, Huang Z, Wang RK. Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography. Journal of the Royal Society Interface. 2012 May 7;9(70):831-841.

Author

Li, Chunhui; Guan, Guangying; Reif, Roberto; Huang, Zhihong; Wang, Ruikang K. / Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography.

In: Journal of the Royal Society Interface, Vol. 9, No. 70, 07.05.2012, p. 831-841.

Research output: Contribution to journalArticle

Bibtex - Download

@article{cefcb65dc3f645b7a1461a2ed992952a,
title = "Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography",
author = "Chunhui Li and Guangying Guan and Roberto Reif and Zhihong Huang and Wang, {Ruikang K.}",
year = "2012",
volume = "9",
number = "70",
pages = "831--841",
journal = "Journal of the Royal Society Interface",
issn = "1742-5689",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography

A1 - Li,Chunhui

A1 - Guan,Guangying

A1 - Reif,Roberto

A1 - Huang,Zhihong

A1 - Wang,Ruikang K.

AU - Li,Chunhui

AU - Guan,Guangying

AU - Reif,Roberto

AU - Huang,Zhihong

AU - Wang,Ruikang K.

PY - 2012/5/7

Y1 - 2012/5/7

N2 - The mechanical properties of skin are important tissue parameters that are useful for understanding skin patho-physiology, which can aid disease diagnosis and treatment. This paper presents an innovative method that employs phase-sensitive spectral-domain optical coherence tomography (PhS-OCT) to characterize the biomechanical properties of skin by measuring surface waves induced by short impulses from a home-made shaker. Experiments are carried out on single and double-layer agar-agar phantoms, of different concentrations and thickness, and on in vivo human skin, at the forearm and the palm. For each experiment, the surface wave phase-velocity dispersion curves were calculated, from which the elasticity of each layer of the sample was determined. It is demonstrated that the experimental results agree well with previous work. This study provides a novel combination of PhS-OCT technology with a simple and an inexpensive mechanical impulse surface wave stimulation that can be used to non-invasively evaluate the mechanical properties of skin in vivo, and may offer potential use in clinical situations. © 2011 The Royal Society.

AB - The mechanical properties of skin are important tissue parameters that are useful for understanding skin patho-physiology, which can aid disease diagnosis and treatment. This paper presents an innovative method that employs phase-sensitive spectral-domain optical coherence tomography (PhS-OCT) to characterize the biomechanical properties of skin by measuring surface waves induced by short impulses from a home-made shaker. Experiments are carried out on single and double-layer agar-agar phantoms, of different concentrations and thickness, and on in vivo human skin, at the forearm and the palm. For each experiment, the surface wave phase-velocity dispersion curves were calculated, from which the elasticity of each layer of the sample was determined. It is demonstrated that the experimental results agree well with previous work. This study provides a novel combination of PhS-OCT technology with a simple and an inexpensive mechanical impulse surface wave stimulation that can be used to non-invasively evaluate the mechanical properties of skin in vivo, and may offer potential use in clinical situations. © 2011 The Royal Society.

KW - phase-sensitive optical coherence tomography PhS-OCT

KW - phase-sensitive measurement

KW - Surface waves

KW - phase-velocity dispersion

KW - skin mechanical properties

UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-84857349240&md5=def39ae932c1c924e621cd9103f13296

U2 - 10.1098/rsif.2011.0583

DO - 10.1098/rsif.2011.0583

M1 - Article

JO - Journal of the Royal Society Interface

JF - Journal of the Royal Society Interface

SN - 1742-5689

IS - 70

VL - 9

SP - 831

EP - 841

ER -

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