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Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions

Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions

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Authors

  • Joseph L.Y. Liu
  • Tanya Walsh
  • Alexander R. Kerr
  • Mark Lingen
  • Paul Brocklehurst
  • Graham Ogden
  • Saman Warnakulasuriya
  • Crispian Scully

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Info

Original languageEnglish
???articleNumber???CD010276
Pages1-19
Number of pages19
JournalCochrane Database of Systematic Reviews
Journal publication dateDec 2012
Journal number12
DOIs
StatePublished

Abstract

The objectives are as follows:
To estimate the accuracy of index tests for the detection of oral cancer and potentially malignant disorders of the lip and oral cavity in patients presenting with clinically evident lesions.
To estimate the relative accuracy of the different tests.

We will use meta-regression to explore possible sources of heterogeneity. Covariates in these analyses will include:
• characteristics of the study sample: prevalence of the disease in the study, the type of specialist (e.g. frontline clinicians, specialists and ’super-specialists’, i.e. those who see surveillance populations), setting (country, type of facility), proportion of human papillomavirus positive adults, tobacco users/high alcohol consumption; and
• target conditions: the nature of target conditions included.
This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2012, Issue 12. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.’

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