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Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells

Effects of aldosterone and related steroids on LPS-induced increased expression of inducible NOS in rat aortic smooth muscle cells

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Original languageEnglish
Pages2003-2014
Number of pages12
JournalBritish Journal of Pharmacology
Journal publication dateDec 2011
Volume164
Issue8
DOIs
StatePublished
Peer-reviewedYes

Abstract

BACKGROUND AND PURPOSE Expression of inducible NOS (iNOS) is important in certain inflammatory diseases. We determined if the hormone aldosterone, a mineralocorticoid receptor (MR) agonist, affects LPS activation of iNOS expression in rat aortic smooth muscle cells (RASMC).

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