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Efficacy and cost of an exercise program for functionally impaired older patients with heart failure

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Efficacy and cost of an exercise program for functionally impaired older patients with heart failure : a randomized controlled trial. / Witham, Miles D. (Lead / Corresponding author); Fulton, Roberta L.; Greig, Carol A.; Johnston, Derek W.; Lang, Chim C.; van der Pol, Marjon; Boyers, Dwayne; Struthers, Allan D.; McMurdo, Marion E. T.

In: Circulation: Heart Failure, Vol. 5, No. 2, 2012, p. 209-216.

Research output: Contribution to journalArticle

Harvard

Witham, MD, Fulton, RL, Greig, CA, Johnston, DW, Lang, CC, van der Pol, M, Boyers, D, Struthers, AD & McMurdo, MET 2012, 'Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial' Circulation: Heart Failure, vol 5, no. 2, pp. 209-216.

APA

Witham, M. D., Fulton, R. L., Greig, C. A., Johnston, D. W., Lang, C. C., van der Pol, M., Boyers, D., Struthers, A. D., & McMurdo, M. E. T. (2012). Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial. Circulation: Heart Failure, 5(2), 209-216doi: 10.1161/CIRCHEARTFAILURE.111.963132

Vancouver

Witham MD, Fulton RL, Greig CA, Johnston DW, Lang CC, van der Pol M et al. Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial. Circulation: Heart Failure. 2012;5(2):209-216.

Author

Witham, Miles D. (Lead / Corresponding author); Fulton, Roberta L.; Greig, Carol A.; Johnston, Derek W.; Lang, Chim C.; van der Pol, Marjon; Boyers, Dwayne; Struthers, Allan D.; McMurdo, Marion E. T. / Efficacy and cost of an exercise program for functionally impaired older patients with heart failure : a randomized controlled trial.

In: Circulation: Heart Failure, Vol. 5, No. 2, 2012, p. 209-216.

Research output: Contribution to journalArticle

Bibtex - Download

@article{fed3c11269a947bfa7504f22cbe91c76,
title = "Efficacy and cost of an exercise program for functionally impaired older patients with heart failure",
author = "Witham, {Miles D.} and Fulton, {Roberta L.} and Greig, {Carol A.} and Johnston, {Derek W.} and Lang, {Chim C.} and {van der Pol}, Marjon and Dwayne Boyers and Struthers, {Allan D.} and McMurdo, {Marion E. T.}",
year = "2012",
volume = "5",
number = "2",
pages = "209--216",
journal = "Circulation: Heart Failure",
issn = "1941-3289",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Efficacy and cost of an exercise program for functionally impaired older patients with heart failure

T2 - a randomized controlled trial

A1 - Witham,Miles D.

A1 - Fulton,Roberta L.

A1 - Greig,Carol A.

A1 - Johnston,Derek W.

A1 - Lang,Chim C.

A1 - van der Pol,Marjon

A1 - Boyers,Dwayne

A1 - Struthers,Allan D.

A1 - McMurdo,Marion E. T.

AU - Witham,Miles D.

AU - Fulton,Roberta L.

AU - Greig,Carol A.

AU - Johnston,Derek W.

AU - Lang,Chim C.

AU - van der Pol,Marjon

AU - Boyers,Dwayne

AU - Struthers,Allan D.

AU - McMurdo,Marion E. T.

PY - 2012

Y1 - 2012

N2 - <p>Background-Little is known about the optimum way to deliver exercise to older, functionally impaired patients with heart failure. We tested whether an exercise program tailored to the needs of these patients could improve exercise capacity and quality of life or reduce costs to the National Health Service.</p><p>Methods and Results-The study design was a parallel-group, single-blind, randomized controlled trial. Patients aged &gt;= 70 years with symptomatic heart failure and left ventricular systolic dysfunction were randomized to either 24 weeks of exercise training or usual care. Six-minute walk distance was the primary outcome; markers of physical function, quality of life, health status, and daily activity were measured at baseline and 8 and 24 weeks. Carer strain and healthcare costs were also recorded. A total of 107 participants were randomized (mean age, 80 years; men, 72 [67%]). Six-minute walk distance did not improve compared to that of the control group at 8 weeks (-16.9 m; 95% CI, -41.8 to 7.9 m; P=0.18) or at 24 weeks (-5.3 m; 95% CI, -32.6 to 22.0 m; P=0.70). For secondary outcomes, only the sit-to-stand test improved significantly at 24 weeks (-6.4 s; 95% CI, -12.2 to 0.6 s; P=0.03); there was no difference in change for the Minnesota Living With Heart Failure score (0.1 points; 95% CI, -0.9 to 1.1 points; P=0.83) at 24 weeks. Carer strain did not decrease at 24 weeks (difference, -0.5 points; 95% CI, -8.3 to 7.3 points; P=0.80), and there was no difference in overall healthcare costs.</p><p>Conclusions-This exercise intervention did not improve exercise capacity or quality of life in older patients with heart failure and was not cost saving to the National Health Service.</p>

AB - <p>Background-Little is known about the optimum way to deliver exercise to older, functionally impaired patients with heart failure. We tested whether an exercise program tailored to the needs of these patients could improve exercise capacity and quality of life or reduce costs to the National Health Service.</p><p>Methods and Results-The study design was a parallel-group, single-blind, randomized controlled trial. Patients aged &gt;= 70 years with symptomatic heart failure and left ventricular systolic dysfunction were randomized to either 24 weeks of exercise training or usual care. Six-minute walk distance was the primary outcome; markers of physical function, quality of life, health status, and daily activity were measured at baseline and 8 and 24 weeks. Carer strain and healthcare costs were also recorded. A total of 107 participants were randomized (mean age, 80 years; men, 72 [67%]). Six-minute walk distance did not improve compared to that of the control group at 8 weeks (-16.9 m; 95% CI, -41.8 to 7.9 m; P=0.18) or at 24 weeks (-5.3 m; 95% CI, -32.6 to 22.0 m; P=0.70). For secondary outcomes, only the sit-to-stand test improved significantly at 24 weeks (-6.4 s; 95% CI, -12.2 to 0.6 s; P=0.03); there was no difference in change for the Minnesota Living With Heart Failure score (0.1 points; 95% CI, -0.9 to 1.1 points; P=0.83) at 24 weeks. Carer strain did not decrease at 24 weeks (difference, -0.5 points; 95% CI, -8.3 to 7.3 points; P=0.80), and there was no difference in overall healthcare costs.</p><p>Conclusions-This exercise intervention did not improve exercise capacity or quality of life in older patients with heart failure and was not cost saving to the National Health Service.</p>

U2 - 10.1161/CIRCHEARTFAILURE.111.963132

DO - 10.1161/CIRCHEARTFAILURE.111.963132

M1 - Article

JO - Circulation: Heart Failure

JF - Circulation: Heart Failure

SN - 1941-3289

IS - 2

VL - 5

SP - 209

EP - 216

ER -

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