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Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry

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Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry. / Li, Chunhui; Huang, Zhihong; Wang, Ruikang K.

In: Optics Express, Vol. 19, No. 11, 2011, p. 10153-10163.

Research output: Contribution to journalArticle

Harvard

Li, C, Huang, Z & Wang, RK 2011, 'Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry' Optics Express, vol 19, no. 11, pp. 10153-10163.

APA

Li, C., Huang, Z., & Wang, R. K. (2011). Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry. Optics Express, 19(11), 10153-10163doi: 10.1364/OE.19.010153

Vancouver

Li C, Huang Z, Wang RK. Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry. Optics Express. 2011;19(11):10153-10163.

Author

Li, Chunhui; Huang, Zhihong; Wang, Ruikang K. / Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry.

In: Optics Express, Vol. 19, No. 11, 2011, p. 10153-10163.

Research output: Contribution to journalArticle

Bibtex - Download

@article{604542596858490995a1466d6c9bc9a6,
title = "Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry",
author = "Chunhui Li and Zhihong Huang and Wang, {Ruikang K.}",
note = "Copyright 2011 Elsevier B.V., All rights reserved.",
year = "2011",
volume = "19",
number = "11",
pages = "10153--10163",
journal = "Optics Express",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Elastic properties of soft tissue-mimicking phantoms assessed by combined use of laser ultrasonics and low coherence interferometry

A1 - Li,Chunhui

A1 - Huang,Zhihong

A1 - Wang,Ruikang K.

AU - Li,Chunhui

AU - Huang,Zhihong

AU - Wang,Ruikang K.

PY - 2011

Y1 - 2011

N2 - Advances in the field of laser ultrasonics have opened up new possibilities in medical applications. This paper evaluates this technique as a method that would allow for rapid characterization of the elastic properties of soft biological tissue. In doing so, we propose a novel approach that utilizes a low coherence interferometer to detect the laser-induced surface acoustic waves (SAW) from the tissue-mimicking phantoms. A Nd:YAG focused laser line-source is applied to one- and two-layer tissue-mimicking agar-agar phantoms, and the generated SAW signals are detected by a time domain low coherence interferometry system. SAW phase velocity dispersion curves are calculated, from which the elasticity of the specimens is evaluated. We show that the experimental results agree well with those of the theoretical expectations. This study is the first report that a laser-generated SAW phase velocity dispersion technique is applied to soft materials. This technique may open a way for laser ultrasonics to detect the mechanical properties of soft tissues, such as skin.

AB - Advances in the field of laser ultrasonics have opened up new possibilities in medical applications. This paper evaluates this technique as a method that would allow for rapid characterization of the elastic properties of soft biological tissue. In doing so, we propose a novel approach that utilizes a low coherence interferometer to detect the laser-induced surface acoustic waves (SAW) from the tissue-mimicking phantoms. A Nd:YAG focused laser line-source is applied to one- and two-layer tissue-mimicking agar-agar phantoms, and the generated SAW signals are detected by a time domain low coherence interferometry system. SAW phase velocity dispersion curves are calculated, from which the elasticity of the specimens is evaluated. We show that the experimental results agree well with those of the theoretical expectations. This study is the first report that a laser-generated SAW phase velocity dispersion technique is applied to soft materials. This technique may open a way for laser ultrasonics to detect the mechanical properties of soft tissues, such as skin.

KW - THIN-FILMS

KW - GENERATION

KW - LINE SOURCE

KW - CONSTANTS

KW - ACOUSTIC-WAVES

KW - FE SIMULATION

KW - SURFACE-LAYERS

UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-79957600000&md5=970b7f9aa5a6c3388f8af4fdf40e7b1d

U2 - 10.1364/OE.19.010153

DO - 10.1364/OE.19.010153

M1 - Article

JO - Optics Express

JF - Optics Express

IS - 11

VL - 19

SP - 10153

EP - 10163

ER -

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