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Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins

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Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins. / Alexandru, G.

Ubiquitin family modifiers and the proteasome: reviews and protocols. ed. / R. Jürgen Dohmen ; Martin Scheffner. Humana Press, 2012. p. 305-312 (Methods in molecular biology; Vol. 832).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Harvard

Alexandru, G 2012, 'Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins'. in RJ Dohmen & M Scheffner (eds), Ubiquitin family modifiers and the proteasome: reviews and protocols. Methods in molecular biology, vol. 832, Humana Press, pp. 305-312., 10.1007/978-1-61779-474-2_21

APA

Alexandru, G. (2012). Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins. In R. J. Dohmen , & M. Scheffner (Eds.), Ubiquitin family modifiers and the proteasome: reviews and protocols. (pp. 305-312). (Methods in molecular biology; Vol. 832). Humana Press. 10.1007/978-1-61779-474-2_21

Vancouver

Alexandru G. Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins. In Dohmen RJ, Scheffner M, editors, Ubiquitin family modifiers and the proteasome: reviews and protocols. Humana Press. 2012. p. 305-312. (Methods in molecular biology). Available from: 10.1007/978-1-61779-474-2_21

Author

Alexandru, G. / Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins.

Ubiquitin family modifiers and the proteasome: reviews and protocols. ed. / R. Jürgen Dohmen ; Martin Scheffner. Humana Press, 2012. p. 305-312 (Methods in molecular biology; Vol. 832).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

Bibtex - Download

@inbook{e480c97ee9444dc8bbd302e8865cb1d1,
title = "Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins",
publisher = "Humana Press",
author = "G. Alexandru",
year = "2012",
doi = "10.1007/978-1-61779-474-2_21",
editor = "Dohmen, {R. Jürgen} and Martin Scheffner",
isbn = "9781617794735",
series = "Methods in molecular biology",
pages = "305-312",
booktitle = "Ubiquitin family modifiers and the proteasome",

}

RIS (suitable for import to EndNote) - Download

TY - CHAP

T1 - Exploring the role of p97 and its UBX-domain cofactors through identification of their interacting proteins

A1 - Alexandru,G.

AU - Alexandru,G.

PB - Humana Press

PY - 2012

Y1 - 2012

N2 - The elucidation of protein-protein interaction networks can provide preliminary insights into the function of uncharacterized proteins based on the interactions they establish in the cell. Here, we describe a protein immunoprecipitation protocol that can be used in combination with mass spectrometry analysis to identify the p97 interactome as well as specific subgroups of proteins interacting with its UBX-domain adaptors. This approach aims to dissect the role played by individual UBX cofactors within the complex array of cellular functions performed by p97. © 2012 Springer Science+Business Media, LLC.

AB - The elucidation of protein-protein interaction networks can provide preliminary insights into the function of uncharacterized proteins based on the interactions they establish in the cell. Here, we describe a protein immunoprecipitation protocol that can be used in combination with mass spectrometry analysis to identify the p97 interactome as well as specific subgroups of proteins interacting with its UBX-domain adaptors. This approach aims to dissect the role played by individual UBX cofactors within the complex array of cellular functions performed by p97. © 2012 Springer Science+Business Media, LLC.

UR - http://www.scopus.com/inward/record.url?scp=84858187770&partnerID=8YFLogxK

U2 - 10.1007/978-1-61779-474-2_21

DO - 10.1007/978-1-61779-474-2_21

M1 - Chapter (peer-reviewed)

SN - 9781617794735

BT - Ubiquitin family modifiers and the proteasome

T2 - Ubiquitin family modifiers and the proteasome

A2 - Scheffner,Martin

ED - Scheffner,Martin

T3 - Methods in molecular biology

T3 - en_GB

SP - 305

EP - 312

ER -

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