TY - JOUR T1 - Hypoglycaemia T2 - exercise for the brain? A1 - Ashford,Michael A1 - Beall,Craig A1 - McCrimmon,Rory AU - Ashford,Michael AU - Beall,Craig AU - McCrimmon,Rory PY - 2012/10 Y1 - 2012/10 N2 -

Low blood sugar, or hypoglycaemia, is detected by specialised sugar sensing neurones in the brain. However, the detection of hypoglycaemia is blunted after repeated hypoglycaemia and this is a result of adaptive mechanisms kicking in within the brain; mechanisms that resemble the training effect in muscle. These adaptations most likely not only increase the tolerance of the brain to stress, but also perturb the detection of hypoglycaemia, further increasing the likelihood of hypoglycaemia.

AB -

Low blood sugar, or hypoglycaemia, is detected by specialised sugar sensing neurones in the brain. However, the detection of hypoglycaemia is blunted after repeated hypoglycaemia and this is a result of adaptive mechanisms kicking in within the brain; mechanisms that resemble the training effect in muscle. These adaptations most likely not only increase the tolerance of the brain to stress, but also perturb the detection of hypoglycaemia, further increasing the likelihood of hypoglycaemia.

U2 - 10.1111/j.1365-2826.2012.02345.x DO - 10.1111/j.1365-2826.2012.02345.x M1 - Article JO - Journal of Neuroendocrinology JF - Journal of Neuroendocrinology SN - 0953-8194 IS - 10 VL - 24 SP - 1365 EP - 1366 ER -