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Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study

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Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study. / de Vries, E.; Trakatelli, M.; Kalabalikis, D.; Ferrandiz, L.; Ruiz-de-Casas, A.; Moreno-Ramirez, D.; Sotiriadis, D.; Ioannides, D.; Aquilina, S.; Apap, C.; Micallef, R.; Scerri, L.; Ulrich, M.; Pitkanen, S.; Saksela, O.; Altsitsiadis, E.; Hinrichs, B.; Magnoni, C.; Fiorentini, C.; Majewski, S.; Ranki, A.; Stockfleth, E.; Proby, C.; EPIDERM Grp.

In: British Journal of Dermatology, Vol. 167, 08.2012, p. 1-13.

Research output: Contribution to journalArticle

Harvard

de Vries, E, Trakatelli, M, Kalabalikis, D, Ferrandiz, L, Ruiz-de-Casas, A, Moreno-Ramirez, D, Sotiriadis, D, Ioannides, D, Aquilina, S, Apap, C, Micallef, R, Scerri, L, Ulrich, M, Pitkanen, S, Saksela, O, Altsitsiadis, E, Hinrichs, B, Magnoni, C, Fiorentini, C, Majewski, S, Ranki, A, Stockfleth, E, Proby, C & EPIDERM Grp 2012, 'Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study' British Journal of Dermatology, vol 167, pp. 1-13.

APA

de Vries, E., Trakatelli, M., Kalabalikis, D., Ferrandiz, L., Ruiz-de-Casas, A., Moreno-Ramirez, D., Sotiriadis, D., Ioannides, D., Aquilina, S., Apap, C., Micallef, R., Scerri, L., Ulrich, M., Pitkanen, S., Saksela, O., Altsitsiadis, E., Hinrichs, B., Magnoni, C., Fiorentini, C., Majewski, S., Ranki, A., Stockfleth, E., Proby, C., & EPIDERM Grp (2012). Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study. British Journal of Dermatology, 167, 1-13doi: 10.1111/j.1365-2133.2012.11081.x

Vancouver

de Vries E, Trakatelli M, Kalabalikis D, Ferrandiz L, Ruiz-de-Casas A, Moreno-Ramirez D et al. Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study. British Journal of Dermatology. 2012 Aug;167:1-13.

Author

de Vries, E.; Trakatelli, M.; Kalabalikis, D.; Ferrandiz, L.; Ruiz-de-Casas, A.; Moreno-Ramirez, D.; Sotiriadis, D.; Ioannides, D.; Aquilina, S.; Apap, C.; Micallef, R.; Scerri, L.; Ulrich, M.; Pitkanen, S.; Saksela, O.; Altsitsiadis, E.; Hinrichs, B.; Magnoni, C.; Fiorentini, C.; Majewski, S.; Ranki, A.; Stockfleth, E.; Proby, C.; EPIDERM Grp / Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study.

In: British Journal of Dermatology, Vol. 167, 08.2012, p. 1-13.

Research output: Contribution to journalArticle

Bibtex - Download

@article{657f2d7d5fc64f1da6685909d763398f,
title = "Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study",
author = "{de Vries}, E. and M. Trakatelli and D. Kalabalikis and L. Ferrandiz and A. Ruiz-de-Casas and D. Moreno-Ramirez and D. Sotiriadis and D. Ioannides and S. Aquilina and C. Apap and R. Micallef and L. Scerri and M. Ulrich and S. Pitkanen and O. Saksela and E. Altsitsiadis and B. Hinrichs and C. Magnoni and C. Fiorentini and S. Majewski and A. Ranki and E. Stockfleth and C. Proby and {EPIDERM Grp}",
year = "2012",
volume = "167",
pages = "1--13",
journal = "British Journal of Dermatology",
issn = "0007-0963",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study

A1 - de Vries,E.

A1 - Trakatelli,M.

A1 - Kalabalikis,D.

A1 - Ferrandiz,L.

A1 - Ruiz-de-Casas,A.

A1 - Moreno-Ramirez,D.

A1 - Sotiriadis,D.

A1 - Ioannides,D.

A1 - Aquilina,S.

A1 - Apap,C.

A1 - Micallef,R.

A1 - Scerri,L.

A1 - Ulrich,M.

A1 - Pitkanen,S.

A1 - Saksela,O.

A1 - Altsitsiadis,E.

A1 - Hinrichs,B.

A1 - Magnoni,C.

A1 - Fiorentini,C.

A1 - Majewski,S.

A1 - Ranki,A.

A1 - Stockfleth,E.

A1 - Proby,C.

A1 - EPIDERM Grp

AU - de Vries,E.

AU - Trakatelli,M.

AU - Kalabalikis,D.

AU - Ferrandiz,L.

AU - Ruiz-de-Casas,A.

AU - Moreno-Ramirez,D.

AU - Sotiriadis,D.

AU - Ioannides,D.

AU - Aquilina,S.

AU - Apap,C.

AU - Micallef,R.

AU - Scerri,L.

AU - Ulrich,M.

AU - Pitkanen,S.

AU - Saksela,O.

AU - Altsitsiadis,E.

AU - Hinrichs,B.

AU - Magnoni,C.

AU - Fiorentini,C.

AU - Majewski,S.

AU - Ranki,A.

AU - Stockfleth,E.

AU - Proby,C.

AU - EPIDERM Grp

PY - 2012/8

Y1 - 2012/8

N2 - <p>Background During recent years numerous studies have suggested that personal and environmental factors might influence cancer development. Objectives To investigate environmental and personal characteristics associated with skin cancer risk. Methods A multicentre hospital-based casecontrol study was performed in Finland, Germany, Greece, Italy, Malta, Poland, Scotland and Spain, including 409 patients with squamous cell carcinoma (SCC), 602 with basal cell carcinoma (BCC) and 360 with cutaneous malignant melanoma (CMM) and 1550 control persons. Exposures were assessed by questionnaires that were partly self-administered, partly completed by dermatologists. Unconditional logistic regression modelling was used to assess associations including the influence of certain drugs and food items on skin cancer risk. Results The usual associations were observed for sun exposure and pigmentation characteristics, with chronic sun exposure being most strongly associated with SCC risk, and naevi and atypical naevi with CMM risk. Use of ciprofloxacin was associated with a decreased risk of BCC [odds ratio (OR) 0.33] and use of thiazide diuretics was associated with an increased risk of SCC (OR 1.66). Ciprofloxacin was also associated with SCC (OR 0.34) and thiazines with BCC (OR 2.04), but these associations lost significance after correction for multiple testing. Consumption of pomegranate, rich in antioxidants, was associated with decreased BCC and SCC risk, also after correcting for multiple testing. Recent experience of stressful events was associated with increased risk, particularly of CMM. Conclusions In this large casecontrol study from across Europe the expected associations were observed for known risk factors. Some new potential protective factors and potential risk factors were identified for consumption of certain food items, medication use and stress, which deserve further investigation in future studies.</p>

AB - <p>Background During recent years numerous studies have suggested that personal and environmental factors might influence cancer development. Objectives To investigate environmental and personal characteristics associated with skin cancer risk. Methods A multicentre hospital-based casecontrol study was performed in Finland, Germany, Greece, Italy, Malta, Poland, Scotland and Spain, including 409 patients with squamous cell carcinoma (SCC), 602 with basal cell carcinoma (BCC) and 360 with cutaneous malignant melanoma (CMM) and 1550 control persons. Exposures were assessed by questionnaires that were partly self-administered, partly completed by dermatologists. Unconditional logistic regression modelling was used to assess associations including the influence of certain drugs and food items on skin cancer risk. Results The usual associations were observed for sun exposure and pigmentation characteristics, with chronic sun exposure being most strongly associated with SCC risk, and naevi and atypical naevi with CMM risk. Use of ciprofloxacin was associated with a decreased risk of BCC [odds ratio (OR) 0.33] and use of thiazide diuretics was associated with an increased risk of SCC (OR 1.66). Ciprofloxacin was also associated with SCC (OR 0.34) and thiazines with BCC (OR 2.04), but these associations lost significance after correction for multiple testing. Consumption of pomegranate, rich in antioxidants, was associated with decreased BCC and SCC risk, also after correcting for multiple testing. Recent experience of stressful events was associated with increased risk, particularly of CMM. Conclusions In this large casecontrol study from across Europe the expected associations were observed for known risk factors. Some new potential protective factors and potential risk factors were identified for consumption of certain food items, medication use and stress, which deserve further investigation in future studies.</p>

U2 - 10.1111/j.1365-2133.2012.11081.x

DO - 10.1111/j.1365-2133.2012.11081.x

M1 - Article

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

VL - 167

SP - 1

EP - 13

ER -

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