Discovery - University of Dundee - Online Publications

Library & Learning Centre

Laser-nucleated acoustic cavitation in focused ultrasound

Laser-nucleated acoustic cavitation in focused ultrasound

Research output: Contribution to journalArticle

View graph of relations


  • Bjoern Gerold
  • Spiros Kotopoulis
  • Craig McDougall
  • David McGloin
  • Michiel Postema
  • Paul Prentice

Research units


Original languageEnglish
Article number044902
Pages (from-to)-
Number of pages9
JournalReview of Scientific Instruments
Issue number4
StatePublished - Apr 2011


Acoustic cavitation can occur in therapeutic applications of high-amplitude focused ultrasound. Studying acoustic cavitation has been challenging, because the onset of nucleation is unpredictable. We hypothesized that acoustic cavitation can be forced to occur at a specific location using a laser to nucleate a microcavity in a pre-established ultrasound field. In this paper we describe a scientific instrument that is dedicated to this outcome, combining a focused ultrasound transducer with a pulsed laser. We present high-speed photographic observations of laser-induced cavitation and laser-nucleated acoustic cavitation, at frame rates of 0.5 x 10(6) frames per second, from laser pulses of energy above and below the optical breakdown threshold, respectively. Acoustic recordings demonstrated inertial cavitation can be controllably introduced to the ultrasound focus. This technique will contribute to the understanding of cavitation evolution in focused ultrasound including for potential therapeutic applications. (C) 2011 American Institute of Physics. [doi:10.1063/1.3579499]



Library & Learning Centre

Contact | Accessibility | Policy