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Laser-nucleated acoustic cavitation in focused ultrasound

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Laser-nucleated acoustic cavitation in focused ultrasound. / Gerold, Bjoern; Kotopoulis, Spiros; McDougall, Craig; McGloin, David; Postema, Michiel; Prentice, Paul.

In: Review of Scientific Instruments, Vol. 82, No. 4, 044902, 04.2011, p. -.

Research output: Contribution to journalArticle

Harvard

Gerold, B, Kotopoulis, S, McDougall, C, McGloin, D, Postema, M & Prentice, P 2011, 'Laser-nucleated acoustic cavitation in focused ultrasound' Review of Scientific Instruments, vol 82, no. 4, 044902, pp. -.

APA

Gerold, B., Kotopoulis, S., McDougall, C., McGloin, D., Postema, M., & Prentice, P. (2011). Laser-nucleated acoustic cavitation in focused ultrasound. Review of Scientific Instruments, 82(4), -[044902]doi: 10.1063/1.3579499

Vancouver

Gerold B, Kotopoulis S, McDougall C, McGloin D, Postema M, Prentice P. Laser-nucleated acoustic cavitation in focused ultrasound. Review of Scientific Instruments. 2011 Apr;82(4):-. 044902.

Author

Gerold, Bjoern; Kotopoulis, Spiros; McDougall, Craig; McGloin, David; Postema, Michiel; Prentice, Paul / Laser-nucleated acoustic cavitation in focused ultrasound.

In: Review of Scientific Instruments, Vol. 82, No. 4, 044902, 04.2011, p. -.

Research output: Contribution to journalArticle

Bibtex - Download

@article{e0cb7ff2470645419ccbd20e940b1add,
title = "Laser-nucleated acoustic cavitation in focused ultrasound",
author = "Bjoern Gerold and Spiros Kotopoulis and Craig McDougall and David McGloin and Michiel Postema and Paul Prentice",
year = "2011",
volume = "82",
number = "4",
pages = "--",
journal = "Review of Scientific Instruments",
issn = "0034-6748",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Laser-nucleated acoustic cavitation in focused ultrasound

A1 - Gerold,Bjoern

A1 - Kotopoulis,Spiros

A1 - McDougall,Craig

A1 - McGloin,David

A1 - Postema,Michiel

A1 - Prentice,Paul

AU - Gerold,Bjoern

AU - Kotopoulis,Spiros

AU - McDougall,Craig

AU - McGloin,David

AU - Postema,Michiel

AU - Prentice,Paul

PY - 2011/4

Y1 - 2011/4

N2 - <p>Acoustic cavitation can occur in therapeutic applications of high-amplitude focused ultrasound. Studying acoustic cavitation has been challenging, because the onset of nucleation is unpredictable. We hypothesized that acoustic cavitation can be forced to occur at a specific location using a laser to nucleate a microcavity in a pre-established ultrasound field. In this paper we describe a scientific instrument that is dedicated to this outcome, combining a focused ultrasound transducer with a pulsed laser. We present high-speed photographic observations of laser-induced cavitation and laser-nucleated acoustic cavitation, at frame rates of 0.5 x 10(6) frames per second, from laser pulses of energy above and below the optical breakdown threshold, respectively. Acoustic recordings demonstrated inertial cavitation can be controllably introduced to the ultrasound focus. This technique will contribute to the understanding of cavitation evolution in focused ultrasound including for potential therapeutic applications. (C) 2011 American Institute of Physics. [doi:10.1063/1.3579499]</p>

AB - <p>Acoustic cavitation can occur in therapeutic applications of high-amplitude focused ultrasound. Studying acoustic cavitation has been challenging, because the onset of nucleation is unpredictable. We hypothesized that acoustic cavitation can be forced to occur at a specific location using a laser to nucleate a microcavity in a pre-established ultrasound field. In this paper we describe a scientific instrument that is dedicated to this outcome, combining a focused ultrasound transducer with a pulsed laser. We present high-speed photographic observations of laser-induced cavitation and laser-nucleated acoustic cavitation, at frame rates of 0.5 x 10(6) frames per second, from laser pulses of energy above and below the optical breakdown threshold, respectively. Acoustic recordings demonstrated inertial cavitation can be controllably introduced to the ultrasound focus. This technique will contribute to the understanding of cavitation evolution in focused ultrasound including for potential therapeutic applications. (C) 2011 American Institute of Physics. [doi:10.1063/1.3579499]</p>

KW - DYNAMICS

KW - BUBBLES

U2 - 10.1063/1.3579499

DO - 10.1063/1.3579499

M1 - Article

JO - Review of Scientific Instruments

JF - Review of Scientific Instruments

SN - 0034-6748

IS - 4

VL - 82

SP - -

ER -

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