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Nrf2 orchestrates fuel partitioning for cell proliferation

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Nrf2 orchestrates fuel partitioning for cell proliferation. / Hayes, John D.; Ashford, Michael L. J.

In: Cell Metabolism, Vol. 16, No. 2, 2012, p. 139-141.

Research output: Contribution to journalArticle

Harvard

Hayes, JD & Ashford, MLJ 2012, 'Nrf2 orchestrates fuel partitioning for cell proliferation' Cell Metabolism, vol 16, no. 2, pp. 139-141., 10.1016/j.cmet.2012.07.009

APA

Hayes, J. D., & Ashford, M. L. J. (2012). Nrf2 orchestrates fuel partitioning for cell proliferation. Cell Metabolism, 16(2), 139-141. 10.1016/j.cmet.2012.07.009

Vancouver

Hayes JD, Ashford MLJ. Nrf2 orchestrates fuel partitioning for cell proliferation. Cell Metabolism. 2012;16(2):139-141. Available from: 10.1016/j.cmet.2012.07.009

Author

Hayes, John D.; Ashford, Michael L. J. / Nrf2 orchestrates fuel partitioning for cell proliferation.

In: Cell Metabolism, Vol. 16, No. 2, 2012, p. 139-141.

Research output: Contribution to journalArticle

Bibtex - Download

@article{798666ee76fa4fe3ac1554d372e0e91f,
title = "Nrf2 orchestrates fuel partitioning for cell proliferation",
author = "Hayes, {John D.} and Ashford, {Michael L. J.}",
year = "2012",
doi = "10.1016/j.cmet.2012.07.009",
volume = "16",
number = "2",
pages = "139--141",
journal = "Cell Metabolism",
issn = "1550-4131",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Nrf2 orchestrates fuel partitioning for cell proliferation

A1 - Hayes,John D.

A1 - Ashford,Michael L. J.

AU - Hayes,John D.

AU - Ashford,Michael L. J.

PY - 2012

Y1 - 2012

N2 - Why upregulation of the transcription factor Nrf2 increases tumor cell proliferation is unclear. Mitsuishi et al. (2012) now provide evidence that Nrf2 augments purine nucleotide synthesis, thus supporting tissue hypertrophy. This change in cellular metabolism requires loss of Nrf2 repression by Keap1 as well as costimulation via the PI3K-Akt pathway. © 2012 Elsevier Inc.

AB - Why upregulation of the transcription factor Nrf2 increases tumor cell proliferation is unclear. Mitsuishi et al. (2012) now provide evidence that Nrf2 augments purine nucleotide synthesis, thus supporting tissue hypertrophy. This change in cellular metabolism requires loss of Nrf2 repression by Keap1 as well as costimulation via the PI3K-Akt pathway. © 2012 Elsevier Inc.

UR - http://www.scopus.com/inward/record.url?scp=84864674743&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2012.07.009

DO - 10.1016/j.cmet.2012.07.009

M1 - Article

JO - Cell Metabolism

JF - Cell Metabolism

SN - 1550-4131

IS - 2

VL - 16

SP - 139

EP - 141

ER -

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