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Optical manipulation of "drops on rails" in two dimensional microfluidic devices

Optical manipulation of "drops on rails" in two dimensional microfluidic devices

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Info

Original languageEnglish
Title of host publicationOptical Trapping and Optical Micromanipulation VIII
EditorsK Dholakia, GC Spalding
Place of publicationBellingham
PublisherSPIE-International Society for Optical Engineering
Publication date2011
Pages-
Number of pages7
Volume8097
ISBN (Print)9780819487070
DOIs
StatePublished

Conference

ConferenceConference on Optical Trapping and Optical Micromanipulation VIII
CountryUnited States
CitySan Diego
Period21/08/1125/08/11

Abstract

When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.

The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.

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