Optical manipulation of "drops on rails" in two dimensional microfluidic devices. / McDougall, C.; Fradet, E.; Baroud, C. N.; McGloin, D.
Optical Trapping and Optical Micromanipulation VIII. ed. / K Dholakia; GC Spalding. Vol. 8097 Bellingham : SPIE-International Society for Optical Engineering, 2011. p. -.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - CHAP
T1 - Optical manipulation of "drops on rails" in two dimensional microfluidic devices
A1 - McDougall,C.
A1 - Fradet,E.
A1 - Baroud,C. N.
A1 - McGloin,D.
AU - McDougall,C.
AU - Fradet,E.
AU - Baroud,C. N.
AU - McGloin,D.
PB - SPIE-International Society for Optical Engineering
CY - Bellingham
PY - 2011
Y1 - 2011
N2 - <p>When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.</p><p>The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.</p>
AB - <p>When using single microfluidic droplets as isolated biological/chemical micro-reactors or arrays of droplets as 2D assaying tools, control over droplet placement is crucial to successful device implementation. Here we demonstrate a combined mechanical and optical approach to generate highly controllable arrays of droplets in pre-determined 'rails and anchors' patterns on a two-dimensional plane.</p><p>The technique combines passive mechanical forcing with selective laser action. Passive mechanical forcing provides a vehicle for droplet transport and storage and laser induced optical forcing is employed for stopping, guiding or derailing droplets as they pass through the chip. In this way intelligent operations can be performed upon arrays of droplets such as sorting, merging to initiate chemical reactions or selective removal of droplets from a predefined array. The user-generated array may then be held static against a mean flow for prolonged observation.</p>
KW - Microfluidics
KW - Optical manipulation
KW - Droplet fluidics
KW - Droplet chemistry
KW - patterned 2D arrays
U2 - 10.1117/12.893346
DO - 10.1117/12.893346
M1 - Conference contribution
SN - 978-0-81948-707-0
VL - 8097
BT - Optical Trapping and Optical Micromanipulation VIII
T2 - Optical Trapping and Optical Micromanipulation VIII
A2 - Spalding,GC
ED - Spalding,GC
SP - -
ER -