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Quantitative elastography of skin and skin lesion using phase-sensitive OCT (PhS-OCT) and surface wave method

Quantitative elastography of skin and skin lesion using phase-sensitive OCT (PhS-OCT) and surface wave method

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Original languageEnglish
TitleOptical coherence tomography and coherence domain Optical methods in biomedicine xvi
EditorsJA Izatt, JG Fujimoto, VV Tuchin
Place of publicationBellingham
PublisherSPIE-International Society for Optical Engineering
Publication date2012
Pages-
Number of pages4
Volume8213
ISBN (Print)9780819488565
DOIs
StatePublished

Conference

ConferenceConference on Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI/SPIE Photonics West Symposia
CountryUnited States
CitySan Francisco
Period23/01/1225/01/12

Abstract

This paper presents the combination of phase sensitive optical coherence tomography (PhS-OCT) imaging system and surface wave method to achieve quantitative evaluation and elastography of the mechanical properties of in vivo human skin. PhS-OCT measures the surface acoustic waves (SAWs) generated by impulse stimulation from a home-made shaker, and provide the B-frame images for the sample. The surface wave phase velocity dispersion curves were calculated, from which the elasticity of different skin layers were determined. The combination of phase velocities from adjacent two locations generates a quantitative elastography of sample. The experimental results agree well with theoretical expectations and may offer potential use in clinical situations.

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