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Regulation of plant gene expression by alternative splicing

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Regulation of plant gene expression by alternative splicing. / Simpson, Craig G.; Manthri, Sujatha; Raczynska, Katarzyna Dorota; Kalyna, Maria; Lewandowska, Dominika; Kusenda, Branislav; Maronova, Monika; Szweykowska-Kulinska, Zofia; Jarmolowski, Artur; Barta, Andrea; Brown, John W. S.

In: Biochemical Society Transactions, Vol. 38, No. 2, 04.2010, p. 667-671.

Research output: Contribution to journalArticle

Harvard

Simpson, CG, Manthri, S, Raczynska, KD, Kalyna, M, Lewandowska, D, Kusenda, B, Maronova, M, Szweykowska-Kulinska, Z, Jarmolowski, A, Barta, A & Brown, JWS 2010, 'Regulation of plant gene expression by alternative splicing' Biochemical Society Transactions, vol 38, no. 2, pp. 667-671.

APA

Simpson, C. G., Manthri, S., Raczynska, K. D., Kalyna, M., Lewandowska, D., Kusenda, B., Maronova, M., Szweykowska-Kulinska, Z., Jarmolowski, A., Barta, A., & Brown, J. W. S. (2010). Regulation of plant gene expression by alternative splicing. Biochemical Society Transactions, 38(2), 667-671doi: 10.1042/BST0380667

Vancouver

Simpson CG, Manthri S, Raczynska KD, Kalyna M, Lewandowska D, Kusenda B et al. Regulation of plant gene expression by alternative splicing. Biochemical Society Transactions. 2010 Apr;38(2):667-671.

Author

Simpson, Craig G.; Manthri, Sujatha; Raczynska, Katarzyna Dorota; Kalyna, Maria; Lewandowska, Dominika; Kusenda, Branislav; Maronova, Monika; Szweykowska-Kulinska, Zofia; Jarmolowski, Artur; Barta, Andrea; Brown, John W. S. / Regulation of plant gene expression by alternative splicing.

In: Biochemical Society Transactions, Vol. 38, No. 2, 04.2010, p. 667-671.

Research output: Contribution to journalArticle

Bibtex - Download

@article{d60d5b1632a14208883057ca9686d535,
title = "Regulation of plant gene expression by alternative splicing",
author = "Simpson, {Craig G.} and Sujatha Manthri and Raczynska, {Katarzyna Dorota} and Maria Kalyna and Dominika Lewandowska and Branislav Kusenda and Monika Maronova and Zofia Szweykowska-Kulinska and Artur Jarmolowski and Andrea Barta and Brown, {John W. S.}",
year = "2010",
volume = "38",
number = "2",
pages = "667--671",
journal = "Biochemical Society Transactions",
issn = "0300-5127",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Regulation of plant gene expression by alternative splicing

A1 - Simpson,Craig G.

A1 - Manthri,Sujatha

A1 - Raczynska,Katarzyna Dorota

A1 - Kalyna,Maria

A1 - Lewandowska,Dominika

A1 - Kusenda,Branislav

A1 - Maronova,Monika

A1 - Szweykowska-Kulinska,Zofia

A1 - Jarmolowski,Artur

A1 - Barta,Andrea

A1 - Brown,John W. S.

AU - Simpson,Craig G.

AU - Manthri,Sujatha

AU - Raczynska,Katarzyna Dorota

AU - Kalyna,Maria

AU - Lewandowska,Dominika

AU - Kusenda,Branislav

AU - Maronova,Monika

AU - Szweykowska-Kulinska,Zofia

AU - Jarmolowski,Artur

AU - Barta,Andrea

AU - Brown,John W. S.

PY - 2010/4

Y1 - 2010/4

N2 - AS (alternative splicing) is a post-transcriptional process which regulates gene expression through increasing protein complexity and modulating mRNA transcript levels. Regulation of AS depends on interactions between trans-acting protein factors and cis-acting signals in the pre-mRNA (precursor mRNA) transcripts, termed 'combinatorial' control. Dynamic changes in AS patterns reflect changes in abundance, composition and activity of splicing factors in different cell types and in response to cellular or environmental cues. Whereas the SR protein family of splicing factors is well-studied in plants, relatively little is known about other factors influencing the regulation of AS or the consequences of AS on mRNA levels and protein function. To address fundamental questions on AS in plants, we are exploiting a high-resolution RT (reverse transcription) - PCR system to analyse multiple AS events simultaneously. In the present paper, we describe the current applications and development of the AS RT - PCR panel in investigating the roles of splicing factors, cap-binding proteins and nonsense-mediated decay proteins on AS, and examining the extent of AS in genes involved in the same developmental pathway or process. ©The Authors.

AB - AS (alternative splicing) is a post-transcriptional process which regulates gene expression through increasing protein complexity and modulating mRNA transcript levels. Regulation of AS depends on interactions between trans-acting protein factors and cis-acting signals in the pre-mRNA (precursor mRNA) transcripts, termed 'combinatorial' control. Dynamic changes in AS patterns reflect changes in abundance, composition and activity of splicing factors in different cell types and in response to cellular or environmental cues. Whereas the SR protein family of splicing factors is well-studied in plants, relatively little is known about other factors influencing the regulation of AS or the consequences of AS on mRNA levels and protein function. To address fundamental questions on AS in plants, we are exploiting a high-resolution RT (reverse transcription) - PCR system to analyse multiple AS events simultaneously. In the present paper, we describe the current applications and development of the AS RT - PCR panel in investigating the roles of splicing factors, cap-binding proteins and nonsense-mediated decay proteins on AS, and examining the extent of AS in genes involved in the same developmental pathway or process. ©The Authors.

KW - Alternative splicing

KW - Arabidopsis

KW - Precursor mRNA

KW - Splicing factor

UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-77953263360&md5=6bac59989e2d8a3bdeb0c94748d1b16f

U2 - 10.1042/BST0380667

DO - 10.1042/BST0380667

M1 - Article

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

SN - 0300-5127

IS - 2

VL - 38

SP - 667

EP - 671

ER -

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