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Sperm are promiscuous and CatSper is to blame...

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Sperm are promiscuous and CatSper is to blame.... / Barratt, Christopher L. R.; Publicover, Stephen J.

In: EMBO Journal, Vol. 31, No. 7, 04.04.2012, p. 1624-1626.

Research output: Contribution to journalArticle

Harvard

Barratt, CLR & Publicover, SJ 2012, 'Sperm are promiscuous and CatSper is to blame...' EMBO Journal, vol 31, no. 7, pp. 1624-1626., 10.1038/emboj.2012.62

APA

Barratt, C. L. R., & Publicover, S. J. (2012). Sperm are promiscuous and CatSper is to blame...EMBO Journal, 31(7), 1624-1626. 10.1038/emboj.2012.62

Vancouver

Barratt CLR, Publicover SJ. Sperm are promiscuous and CatSper is to blame... EMBO Journal. 2012 Apr 4;31(7):1624-1626. Available from: 10.1038/emboj.2012.62

Author

Barratt, Christopher L. R.; Publicover, Stephen J. / Sperm are promiscuous and CatSper is to blame....

In: EMBO Journal, Vol. 31, No. 7, 04.04.2012, p. 1624-1626.

Research output: Contribution to journalArticle

Bibtex - Download

@article{789c677a35db425da670857bca657d5f,
title = "Sperm are promiscuous and CatSper is to blame...",
author = "Barratt, {Christopher L. R.} and Publicover, {Stephen J.}",
year = "2012",
doi = "10.1038/emboj.2012.62",
volume = "31",
number = "7",
pages = "1624--1626",
journal = "EMBO Journal",
issn = "0261-4189",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Sperm are promiscuous and CatSper is to blame...

A1 - Barratt,Christopher L. R.

A1 - Publicover,Stephen J.

AU - Barratt,Christopher L. R.

AU - Publicover,Stephen J.

PY - 2012/4/4

Y1 - 2012/4/4

N2 - A sperm-specific cation channel (CatSper) facilitates the entry of calcium necessary for rapid changes in sperm motility allowing the cell to navigate the hurdles of the female reproductive tract and successfully to locate the egg. Brenker and colleagues show that CatSper is (directly) activated by a diverse range of small organic molecules that are reported to evoke chemotaxis in human spermatozoa, suggesting that CatSper may function as a polymodal, chemosensory calcium channel. Additionally, they provide strong evidence that calcium entry into the spermatozoon does not employ specific, G protein-coupled odorant receptors or activation of trans-membrane adenylate cyclase and is not induced by cyclic nucleotides. © 2012 European Molecular Biology Organization | All Rights Reserved.

AB - A sperm-specific cation channel (CatSper) facilitates the entry of calcium necessary for rapid changes in sperm motility allowing the cell to navigate the hurdles of the female reproductive tract and successfully to locate the egg. Brenker and colleagues show that CatSper is (directly) activated by a diverse range of small organic molecules that are reported to evoke chemotaxis in human spermatozoa, suggesting that CatSper may function as a polymodal, chemosensory calcium channel. Additionally, they provide strong evidence that calcium entry into the spermatozoon does not employ specific, G protein-coupled odorant receptors or activation of trans-membrane adenylate cyclase and is not induced by cyclic nucleotides. © 2012 European Molecular Biology Organization | All Rights Reserved.

UR - http://www.scopus.com/inward/record.url?scp=84859427468&partnerID=8YFLogxK

U2 - 10.1038/emboj.2012.62

DO - 10.1038/emboj.2012.62

M1 - Article

JO - EMBO Journal

JF - EMBO Journal

SN - 0261-4189

IS - 7

VL - 31

SP - 1624

EP - 1626

ER -

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