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Study protocol for BeWEL

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Study protocol for BeWEL : the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas. / Craigie, Angela M.; Caswell, Stephen; Paterson, Caron; Treweek, Shaun; Belch, Jill J. F.; Daly, Fergus; Rodger, Jackie; Thompson, Joyce; Kirk, Alison; Ludbrook, Anne; Stead, Martine; Wardle, Jane; Steele, Robert J. C.; Anderson, Annie S.

In: BMC Public Health, Vol. 11, 184, 25.03.2011, p. -.

Research output: Contribution to journalArticle

Harvard

Craigie, AM, Caswell, S, Paterson, C, Treweek, S, Belch, JJF, Daly, F, Rodger, J, Thompson, J, Kirk, A, Ludbrook, A, Stead, M, Wardle, J, Steele, RJC & Anderson, AS 2011, 'Study protocol for BeWEL: the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas' BMC Public Health, vol 11, 184, pp. -., 10.1186/1471-2458-11-184

APA

Craigie, A. M., Caswell, S., Paterson, C., Treweek, S., Belch, J. J. F., Daly, F., ... Anderson, A. S. (2011). Study protocol for BeWEL: the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas. BMC Public Health, 11, -. [184]. 10.1186/1471-2458-11-184

Vancouver

Craigie AM, Caswell S, Paterson C, Treweek S, Belch JJF, Daly F et al. Study protocol for BeWEL: the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas. BMC Public Health. 2011 Mar 25;11:-. 184. Available from: 10.1186/1471-2458-11-184

Author

Craigie, Angela M.; Caswell, Stephen; Paterson, Caron; Treweek, Shaun; Belch, Jill J. F.; Daly, Fergus; Rodger, Jackie; Thompson, Joyce; Kirk, Alison; Ludbrook, Anne; Stead, Martine; Wardle, Jane; Steele, Robert J. C.; Anderson, Annie S. / Study protocol for BeWEL : the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas.

In: BMC Public Health, Vol. 11, 184, 25.03.2011, p. -.

Research output: Contribution to journalArticle

Bibtex - Download

@article{22ea1abe1b9349c3a5185b35e48743ae,
title = "Study protocol for BeWEL: the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas",
keywords = "Life-style intervention, Randomized trial, Body size, Cancer, Reduction, Health, Prevention, Metformin, Mortality, People",
author = "Craigie, {Angela M.} and Stephen Caswell and Caron Paterson and Shaun Treweek and Belch, {Jill J. F.} and Fergus Daly and Jackie Rodger and Joyce Thompson and Alison Kirk and Anne Ludbrook and Martine Stead and Jane Wardle and Steele, {Robert J. C.} and Anderson, {Annie S.}",
year = "2011",
doi = "10.1186/1471-2458-11-184",
volume = "11",
pages = "--",
journal = "BMC Public Health",
issn = "1471-2458",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Study protocol for BeWEL

T2 - the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas

A1 - Craigie,Angela M.

A1 - Caswell,Stephen

A1 - Paterson,Caron

A1 - Treweek,Shaun

A1 - Belch,Jill J. F.

A1 - Daly,Fergus

A1 - Rodger,Jackie

A1 - Thompson,Joyce

A1 - Kirk,Alison

A1 - Ludbrook,Anne

A1 - Stead,Martine

A1 - Wardle,Jane

A1 - Steele,Robert J. C.

A1 - Anderson,Annie S.

AU - Craigie,Angela M.

AU - Caswell,Stephen

AU - Paterson,Caron

AU - Treweek,Shaun

AU - Belch,Jill J. F.

AU - Daly,Fergus

AU - Rodger,Jackie

AU - Thompson,Joyce

AU - Kirk,Alison

AU - Ludbrook,Anne

AU - Stead,Martine

AU - Wardle,Jane

AU - Steele,Robert J. C.

AU - Anderson,Annie S.

PY - 2011/3/25

Y1 - 2011/3/25

N2 - <p>Background: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second highest cause of cancer death in the UK. Most cases occur in people over 50 years and CRC often co-exists with other lifestyle related disorders including obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). These diseases share risk factors related to the metabolic syndrome including large body size, abnormal lipids and markers of insulin resistance indicating common aetiological pathways.</p><p>Methods/Design: This 3 year study will be a two-arm, multicentre, randomised controlled trial comparing the BeWEL lifestyle (diet, physical activity and behaviour change) programme against usual care. The pre-trial development will take 6 months and participants will be recruited over a 12 month period and undertake the intervention and follow up for 12 months (total 24 months recruitment and intervention implementation) with a further 6 months for data collection, analysis and interpretation. Four hundred and fifty two participants who have had a colorectal adenoma detected and removed (through the national colorectal screening programme) will provide 80% power to detect a weight loss of 7% over 12 months. Primary outcomes are changes in body weight and waist circumference. Secondary outcomes will include cardiovascular risk factors, psycho-social measures and intervention costs.</p><p>Discussion: The results from this study will enhance the evidence base for lifestyle change in patients at higher risk of chronic disease including obesity related cancers.</p>

AB - <p>Background: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second highest cause of cancer death in the UK. Most cases occur in people over 50 years and CRC often co-exists with other lifestyle related disorders including obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). These diseases share risk factors related to the metabolic syndrome including large body size, abnormal lipids and markers of insulin resistance indicating common aetiological pathways.</p><p>Methods/Design: This 3 year study will be a two-arm, multicentre, randomised controlled trial comparing the BeWEL lifestyle (diet, physical activity and behaviour change) programme against usual care. The pre-trial development will take 6 months and participants will be recruited over a 12 month period and undertake the intervention and follow up for 12 months (total 24 months recruitment and intervention implementation) with a further 6 months for data collection, analysis and interpretation. Four hundred and fifty two participants who have had a colorectal adenoma detected and removed (through the national colorectal screening programme) will provide 80% power to detect a weight loss of 7% over 12 months. Primary outcomes are changes in body weight and waist circumference. Secondary outcomes will include cardiovascular risk factors, psycho-social measures and intervention costs.</p><p>Discussion: The results from this study will enhance the evidence base for lifestyle change in patients at higher risk of chronic disease including obesity related cancers.</p>

KW - Life-style intervention

KW - Randomized trial

KW - Body size

KW - Cancer

KW - Reduction

KW - Health

KW - Prevention

KW - Metformin

KW - Mortality

KW - People

U2 - 10.1186/1471-2458-11-184

DO - 10.1186/1471-2458-11-184

M1 - Article

JO - BMC Public Health

JF - BMC Public Health

SN - 1471-2458

VL - 11

SP - -

ER -

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