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The case for randomized controlled trials to assess the impact of clinical information systems

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The case for randomized controlled trials to assess the impact of clinical information systems. / Liu, Joseph L. Y.; Wyatt, Jeremy C.

In: Journal of the American Medical Informatics Association, Vol. 18, No. 2, 03.2011, p. 173-180.

Research output: Contribution to journalArticle

Harvard

Liu, JLY & Wyatt, JC 2011, 'The case for randomized controlled trials to assess the impact of clinical information systems' Journal of the American Medical Informatics Association, vol 18, no. 2, pp. 173-180., 10.1136/jamia.2010.010306

APA

Liu, J. L. Y., & Wyatt, J. C. (2011). The case for randomized controlled trials to assess the impact of clinical information systems. Journal of the American Medical Informatics Association, 18(2), 173-180. 10.1136/jamia.2010.010306

Vancouver

Liu JLY, Wyatt JC. The case for randomized controlled trials to assess the impact of clinical information systems. Journal of the American Medical Informatics Association. 2011 Mar;18(2):173-180. Available from: 10.1136/jamia.2010.010306

Author

Liu, Joseph L. Y.; Wyatt, Jeremy C. / The case for randomized controlled trials to assess the impact of clinical information systems.

In: Journal of the American Medical Informatics Association, Vol. 18, No. 2, 03.2011, p. 173-180.

Research output: Contribution to journalArticle

Bibtex - Download

@article{8a8406ddb04a49c3954cdf46d73b4d77,
title = "The case for randomized controlled trials to assess the impact of clinical information systems",
author = "Liu, {Joseph L. Y.} and Wyatt, {Jeremy C.}",
year = "2011",
doi = "10.1136/jamia.2010.010306",
volume = "18",
number = "2",
pages = "173--180",
journal = "Journal of the American Medical Informatics Association",
issn = "1067-5027",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - The case for randomized controlled trials to assess the impact of clinical information systems

A1 - Liu,Joseph L. Y.

A1 - Wyatt,Jeremy C.

AU - Liu,Joseph L. Y.

AU - Wyatt,Jeremy C.

PY - 2011/3

Y1 - 2011/3

N2 - <p>There is a persistent view of a significant minority in the medical informatics community that the randomized controlled trial (ROT) has a limited role to play in evaluating clinical information systems. A common reason voiced by skeptics is that these systems are fundamentally different from drug interventions, so the RCT is irrelevant. There is an urgent need to promote the use of RCTs, given the shift to evidence-based policy and the need to demonstrate cost-effectiveness of these systems. The authors suggest returning to first principles and argue that what is required is clarity about how to match methods to evaluation questions. The authors address common concerns about RCTs, and the extent to which they are fallacious, and also discuss the challenges of conducting RCTs in informatics and alternative study designs when randomized trials are infeasible. While neither a perfect nor universal evaluation method, RCTs form an important part of an evaluator's toolkit.</p>

AB - <p>There is a persistent view of a significant minority in the medical informatics community that the randomized controlled trial (ROT) has a limited role to play in evaluating clinical information systems. A common reason voiced by skeptics is that these systems are fundamentally different from drug interventions, so the RCT is irrelevant. There is an urgent need to promote the use of RCTs, given the shift to evidence-based policy and the need to demonstrate cost-effectiveness of these systems. The authors suggest returning to first principles and argue that what is required is clarity about how to match methods to evaluation questions. The authors address common concerns about RCTs, and the extent to which they are fallacious, and also discuss the challenges of conducting RCTs in informatics and alternative study designs when randomized trials are infeasible. While neither a perfect nor universal evaluation method, RCTs form an important part of an evaluator's toolkit.</p>

U2 - 10.1136/jamia.2010.010306

DO - 10.1136/jamia.2010.010306

M1 - Article

JO - Journal of the American Medical Informatics Association

JF - Journal of the American Medical Informatics Association

SN - 1067-5027

IS - 2

VL - 18

SP - 173

EP - 180

ER -

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