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The cost-effectiveness of tailored, postal feedback on general practitioners' prescribing of pharmacotherapies for alcohol dependence

The cost-effectiveness of tailored, postal feedback on general practitioners' prescribing of pharmacotherapies for alcohol dependence

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Authors

  • Hector Jose Navarro
  • Anthony Shakeshaft
  • Christopher M. Doran
  • Dennis J. Petrie

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Original languageEnglish
Pages207-215
Number of pages9
JournalDrug and Alcohol Dependence
Journal publication date2012
Journal number3
Volume124
DOIs
StatePublished

Abstract

Aims: The aims of this study were to conduct a randomised controlled trial to evaluate the cost-effectiveness of tailored, postal feedback on general practitioners' (GPs) prescribing of acamprosate and naltrexone for alcohol dependence relative to current practice and its impact on alcohol dependence morbidity. Methods: Rural communities in New South Wales, Australia, were randomised into experimental (N= 10) and control (N= 10) communities. Tailored feedback on their prescribing of alcohol pharmacotherapies was mailed to GPs from the experimental communities (N= 115). Segmented regression analysis was used to examine within and between group changes in prescribing and alcohol dependence hospitalisation rates compared to the control communities. Incremental cost-effectiveness ratios (ICERs) were estimated per additional prescription of pharmacotherapies and per alcohol dependence hospitalisation(s) averted. Results: Post-intervention changes, relative to the control communities, in GPs' prescribing rate trends in the experimental communities significantly increased for acamprosate (ß= 0.24, 95% CI: 0.13-0.35, p

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