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Thermal imaging analysis of 3D biological agarose matrices

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Thermal imaging analysis of 3D biological agarose matrices. / Maher, P.S.; Vorstius, J.B.; Donnelly, Kenneth; Keatch, Robert P.

In: International Journal of Medical Engineering and Informatics, Vol. 3, No. 2, 01.07.2011, p. 167-179.

Research output: Contribution to journalArticle

Harvard

Maher, PS, Vorstius, JB, Donnelly, K & Keatch, RP 2011, 'Thermal imaging analysis of 3D biological agarose matrices' International Journal of Medical Engineering and Informatics, vol 3, no. 2, pp. 167-179., 10.1504/IJMEI.2011.041237

APA

Maher, P. S., Vorstius, J. B., Donnelly, K., & Keatch, R. P. (2011). Thermal imaging analysis of 3D biological agarose matrices. International Journal of Medical Engineering and Informatics, 3(2), 167-179. 10.1504/IJMEI.2011.041237

Vancouver

Maher PS, Vorstius JB, Donnelly K, Keatch RP. Thermal imaging analysis of 3D biological agarose matrices. International Journal of Medical Engineering and Informatics. 2011 Jul 1;3(2):167-179. Available from: 10.1504/IJMEI.2011.041237

Author

Maher, P.S.; Vorstius, J.B.; Donnelly, Kenneth; Keatch, Robert P. / Thermal imaging analysis of 3D biological agarose matrices.

In: International Journal of Medical Engineering and Informatics, Vol. 3, No. 2, 01.07.2011, p. 167-179.

Research output: Contribution to journalArticle

Bibtex - Download

@article{1a319e01d2f2464496cf19ab4001d0d6,
title = "Thermal imaging analysis of 3D biological agarose matrices",
author = "P.S. Maher and J.B. Vorstius and Kenneth Donnelly and Keatch, {Robert P.}",
year = "2011",
doi = "10.1504/IJMEI.2011.041237",
volume = "3",
number = "2",
pages = "167--179",
journal = "International Journal of Medical Engineering and Informatics",
issn = "1755-0653",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Thermal imaging analysis of 3D biological agarose matrices

A1 - Maher,P.S.

A1 - Vorstius,J.B.

A1 - Donnelly,Kenneth

A1 - Keatch,Robert P.

AU - Maher,P.S.

AU - Vorstius,J.B.

AU - Donnelly,Kenneth

AU - Keatch,Robert P.

PY - 2011/7/1

Y1 - 2011/7/1

N2 - Advances in rapid prototyping have allowed for the construction of biocompatible materials (hydrogels) to be used in regenerative medicine. Within this area of construction inherent problems arise due to the mechanical instability of such materials that are temperature dependent. This research paper describes a thermal imaging analysis used to circumvent needle blockage when using an RP technology called bioplotting, used for extruding high temperature hydrogels, where agarose was the experimental biomaterial. The investigation describes how we have overcome these inherent problems through thermal imaging analysis, allowing us to accurately construct 3D biological matrices that have satisfied the in-vitro cell requirements for producing artificial tissue scaffolds. By properly insulating the needle and chamber, we have reduced the time taken for the needle to reach a sufficient plotting temperature. The analysis has allowed us to produce 3D biological matrices that have satisfied the in vitro cell requirements for producing artificial tissue. The analysis reported in this paper has opened the possibility for other high temperature dependent hydrogels to be constructed into 3D biological matrices without delay. Copyright © 2011 Inderscience Enterprises Ltd.

AB - Advances in rapid prototyping have allowed for the construction of biocompatible materials (hydrogels) to be used in regenerative medicine. Within this area of construction inherent problems arise due to the mechanical instability of such materials that are temperature dependent. This research paper describes a thermal imaging analysis used to circumvent needle blockage when using an RP technology called bioplotting, used for extruding high temperature hydrogels, where agarose was the experimental biomaterial. The investigation describes how we have overcome these inherent problems through thermal imaging analysis, allowing us to accurately construct 3D biological matrices that have satisfied the in-vitro cell requirements for producing artificial tissue scaffolds. By properly insulating the needle and chamber, we have reduced the time taken for the needle to reach a sufficient plotting temperature. The analysis has allowed us to produce 3D biological matrices that have satisfied the in vitro cell requirements for producing artificial tissue. The analysis reported in this paper has opened the possibility for other high temperature dependent hydrogels to be constructed into 3D biological matrices without delay. Copyright © 2011 Inderscience Enterprises Ltd.

UR - http://www.scopus.com/inward/record.url?scp=79960442104&partnerID=8YFLogxK

U2 - 10.1504/IJMEI.2011.041237

DO - 10.1504/IJMEI.2011.041237

M1 - Article

JO - International Journal of Medical Engineering and Informatics

JF - International Journal of Medical Engineering and Informatics

SN - 1755-0653

IS - 2

VL - 3

SP - 167

EP - 179

ER -

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