Villoglandular adenocarcinoma of the cervix : clarity is needed on the histological definition for this difficult diagnosis. / Macdonald, R. D. ; Kirwan, J. ; Hayat, K. ; Herrington, C. S. ; Shawki, H. .
In: Gynecologic Oncology, Vol. 100, No. 1, 2006, p. 192-194.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Villoglandular adenocarcinoma of the cervix
T2 - clarity is needed on the histological definition for this difficult diagnosis
A1 - Macdonald,R. D.
A1 - Kirwan,J.
A1 - Hayat,K.
A1 - Herrington,C. S.
A1 - Shawki,H.
AU - Macdonald,R. D.
AU - Kirwan,J.
AU - Hayat,K.
AU - Herrington,C. S.
AU - Shawki,H.
PY - 2006
Y1 - 2006
N2 - <p>Background. Villoglandular adenocarcinoma (VGA) of the cervix is <br/> reported as a variant of a cervical adenocarcinoma with a good <br/> prognosis. Cases. We present two cases histologically reported as a <br/> villoglandular adenocarcinoma of the cervix that have recurred and <br/> progressed rapidly since initial treatment. External histopathological <br/> review suggested both had a prominent villoglandular pattern but with an<br/> associated underlying well-differentiated adenocarcinoma. Conclusion. <br/> The diagnosis of VGA is difficult. Current literature is not entirely <br/> consistent in the presented definition, and further clarity is needed. <br/> Because of the rarity of VGA and the difficulty but importance of the <br/> diagnosis, we would feel that a central review of all cases of VGA is <br/> warranted. This would assist in diagnosis and also in obtaining accurate<br/> follow-up data. © 2005 Elsevier Inc. All rights reserved</p>
AB - <p>Background. Villoglandular adenocarcinoma (VGA) of the cervix is <br/> reported as a variant of a cervical adenocarcinoma with a good <br/> prognosis. Cases. We present two cases histologically reported as a <br/> villoglandular adenocarcinoma of the cervix that have recurred and <br/> progressed rapidly since initial treatment. External histopathological <br/> review suggested both had a prominent villoglandular pattern but with an<br/> associated underlying well-differentiated adenocarcinoma. Conclusion. <br/> The diagnosis of VGA is difficult. Current literature is not entirely <br/> consistent in the presented definition, and further clarity is needed. <br/> Because of the rarity of VGA and the difficulty but importance of the <br/> diagnosis, we would feel that a central review of all cases of VGA is <br/> warranted. This would assist in diagnosis and also in obtaining accurate<br/> follow-up data. © 2005 Elsevier Inc. All rights reserved</p>
U2 - 10.1016/j.ygyno.2005.07.133
DO - 10.1016/j.ygyno.2005.07.133
M1 - Article
JO - Gynecologic Oncology
JF - Gynecologic Oncology
SN - 0090-8258
IS - 1
VL - 100
SP - 192
EP - 194
ER -