Biological Chemistry and Drug Discovery

Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

Glover, L., Hutchinson, S., Alsford, S., McCulloch, R., Field, M. C. & Horn, D. Dec 2013 In : Cellular Microbiology. 15, 12, p. 1984-1993 10 p.

Research output: Contribution to journal › Article

Fragment-based hit identification: thinking in 3D

Morley, A. D., Pugliese, A., Birchall, K., Bower, J., Brennan, P., Brown, N., Chapman, T., Drysdale, M., Gilbert, I. H., Hoelder, S., Jordan, A., Ley, S. V., Merritt, A., Miller, D., Swarbrick, M. E. & Wyatt, P. G. Dec 2013 In : Drug Discovery Today. 18, 23-24, p. 1221-1227 7 p.

Research output: Contribution to journal › Article

Structural basis for type VI secreted peptidoglycan DL-endopeptidase function, specificity and neutralization in Serratia marcescens

Srikannathasan, V., English, G., Bui, N. K., Trunk, K., O'Rourke, P. E. F., Rao, V. A., Vollmer, W., Coulthurst, S. J. & Hunter, W. N. Dec 2013 In : Acta Crystallographica Section D: Biological Crystallography. 69, 12, p. 2468-2482 15 p.

Research output: Contribution to journal › Article

Two high-resolution structures of the human E3 ubiquitin ligase Siah1

Rimsa, V., Eadsforth, T. C. & Hunter, W. N. Dec 2013 In : Acta Crystallographica F-Structural Biology and Crystallization Communications. 69, 12, p. 1339-1343 5 p.

Research output: Contribution to journal › Article

Construction of reference chromosome-scale pseudomolecules for potato: integrating the potato genome with genetic and physical maps

Sharma, S. K. , Bolser, D. , de Boer, J. , Sønderkær, M. , Amoros, W. , Carboni, M. F. , D'Ambrosio, J. M. , de la Cruz, G. , Di Genova, A. , Douches, D. S. , Eguiluz, M. , Guo, X. , Guzman, F. , Hackett, C. A. , Hamilton, J. P. , Li, G. , Li, Y. , Lozano, R. , Maass, A. , Marshall, D. & 25 others Martinez, D., McLean, K., Mejía, N., Milne, L., Munive, S., Nagy, I., Ponce, O., Ramirez, M., Simon, R., Thomson, S. J., Torres, Y., Waugh, R., Zhang, Z., Huang, S., Visser, R. G. F., Bachem, C. W. B., Sagredo, B., Feingold, S. E., Orjeda, G., Veilleux, R. E., Bonierbale, M., Jacobs, J. M. E., Milbourne, D., Martin, D. M. A. & Bryan, G. J. 1 Nov 2013 In : G3 : Genes, Genomes, Genetics. 3, 11, p. 2031-2047 17 p.

Research output: Contribution to journal › Article

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Madhok, V. B. & 33 others Saunders, S. P., Goh, C. S. M., Brown, S. J., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G. 1 Nov 2013 In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

Research output: Contribution to journal › Article

Transcription Termination and Chimeric RNA Formation Controlled by Arabidopsis thaliana FPA

Duc, C., Sherstnev, A., Cole, C., Barton, G. & Simpson, G. G. 31 Oct 2013 In : PLoS Genetics. 9, 10, e1003867

Research output: Contribution to journal › Article

The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative polyadenylation

Lyons, R., Iwase, A., Gänsewig, T., Sherstnev, A., Duc, C., Barton, G. J., Hanada, K., Higuchi-Takeuchi, M., Matsui, M., Sugimoto, K., Kazan, K., Simpson, G. G. & Shirasu, K. 9 Oct 2013 In : Scientific Reports. 3, 10 p.2866

Research output: Contribution to journal › Article

Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy

Ong, H. B., Sienkiewicz, N., Wyllie, S., Patterson, S. & Fairlamb, A. H. Oct 2013 In : Molecular Microbiology. 90, 2, p. 443-455 13 p.

Research output: Contribution to journal › Article