Discovery - University of Dundee - Online Publications

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Biological Chemistry and Drug Discovery

  1. Erratum for De Rycker et al., Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

    De Rycker, M., Hallyburton, I., Thomas, J., Campbell, L., Wyllie, S., Joshi, D., Cameron, S., Gilbert, I. H., Wyatt, P. G., Frearson, J. A., Fairlamb, A. H. & Gray, D. W. Dec 2014 In : Antimicrobial Agents and Chemotherapy. 58, 12, p. 7622 1 p.

    Research output: Contribution to journalArticle

  2. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

    Bago, R., Malik, N., Munson, M. J., Prescott, A. R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I. G. & Alessi, D. R. Nov 2014 In : Biochemical Journal. 463, 3, p. 413-427 15 p.

    Research output: Contribution to journalArticle

  3. The spatial effect of protein deuteration on nitroxide spin-label relaxation: implications for EPR distance measurement

    El Mkami, H., Ward, R., Bowman, A., Owen-Hughes, T. & Norman, D. G. Nov 2014 In : Journal of Magnetic Resonance . 248, p. 36-41 6 p.

    Research output: Contribution to journalArticle

  4. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

    Baud, M. G. J., Lin-Shiao, E., Cardote, T., Tallant, C., Pschibul, A., Chan, K-H., Zengerle, M., Garcia, J. R., Kwan, T. T-L., Ferguson, F. M. & Ciulli, A. 31 Oct 2014 In : Science. 346, 6209, p. 638-641 4 p.

    Research output: Contribution to journalArticle

  5. Characterisation of a melamino nitroheterocycle as a potential lead for the treatment of human African trypanosomiasis

    Giordani, F., Buschini, A., Baliani, A., Kaiser, M., Brun, R., Barrett, M. P., Pellacani, C., Poli, P. & Gilbert, I. H. Oct 2014 In : Antimicrobial Agents and Chemotherapy. 58, 10, p. 5747-5757 11 p.

    Research output: Contribution to journalArticle

  6. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

    Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P. Oct 2014 In : Stem Cells. 32, 10, p. 2605-2615

    Research output: Contribution to journalArticle

  7. Missing pieces of an ancient puzzle: evolution of the Eukaryotic Membrane-Trafficking System

    Schlacht, A., Herman, E. K., Klute, M. J., Field, M. C. & Dacks, J. B. Oct 2014 In : Cold Spring Harbor Perspectives in Biology. 6, 10, a016048

    Research output: Contribution to journalArticle

  8. Reproducible Automated Phosphopeptide Enrichment using Magnetic TiO2 and Ti-IMAC

    Tape, C. J., Worboys, J. D., Sinclair, J., Gourlay, R., Vogt, J., McMahon (Broster), K. M., Trost, M., Lauffenburger, D. A., Lamont, D. J. & Jørgensen, C. 18 Sep 2014 In : Analytical Chemistry. ASAP

    Research output: Contribution to journalArticle

  9. Fragment-Based Screening in Tandem with Phenotypic Screening Provides Novel Antiparasitic Hits

    Blaazer, A. R., Orrling, K. M., Shanmugham, A., Jansen, C., Maes, L., Edink, E., Sterk, G. J., Siderius, M., England, P., Bailey, D., de Esch, I. J. P. & Leurs, R. 17 Sep 2014 In : Journal of Biomolecular Screening.

    Research output: Contribution to journalArticle

  10. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

    Roche, S. L., Sherman, D. L., Dissanayake, K., Soucy, G., Desmazieres, A., Lamont, D. J., Peles, E., Julien, J-P., Wishart, T. M., Ribchester, R. R., Brophy, P. J. & Gillingwater, T. H. 17 Sep 2014 In : Journal of Neuroscience. 34, 38, p. 12904-12918 15 p.

    Research output: Contribution to journalArticle

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