Biological Chemistry and Drug Discovery

TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei

Nakanishi, M., Karasudani, M., Shiraishi, T., Hashida, K., Hino, M., Ferguson, M. A. J. & Nomoto, H. Jun 2014 In : Parasitology International. 63, 3, p. 513-518 6 p.

Research output: Contribution to journal › Article

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-seq and ESTs

Schurch, N. J., Cole, C., Sherstnev, A., Song, J., Duc, C., Storey, K. G., McLean, W. H. I., Brown, S. J., Simpson, G. G. & Barton, G. J. 10 Apr 2014 In : PLoS ONE. 9, 4, e94270

Research output: Contribution to journal › Article

Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase

Urbaniak, M. D., Capes, A. S., Crossman, A., O'Neill, S., Thompson, S., Gilbert, I. H. & Ferguson, M. A. J. 31 Mar 2014 In : Carbohydrate Research. 387, p. 54-58 5 p.

Research output: Contribution to journal › Article

Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues

Capes, A. S., Crossman, A., Urbaniak, M. D., Gilbert, S. H., Ferguson, M. A. J. & Gilbert, I. H. Mar 2014 In : Organic and Biomolecular Chemistry. 12, 12, p. 1919-1934 16 p.

Research output: Contribution to journal › Article

Norspermidine is not a self-produced trigger for biofilm disassembly

Hobley, L., Kim, S. H., Maezato, Y., Wyllie, S., Fairlamb, A. H., Stanley-Wall, N. R. & Michael, A. J. 13 Feb 2014 In : Cell. 156, 4, p. 844-854 11 p.

Research output: Contribution to journal › Article

Evolution of the nucleus

Devos, D. P., Gräf, R. & Field, M. C. 5 Feb 2014 In : Current Opinion in Cell Biology. 28, p. 8-15 8 p.

Research output: Contribution to journal › Article

Bisubstrate UDP-peptide conjugates as human O-GlcNAc transferase inhibitors

Borodkin, V. S., Schimpl, M., Gundogdu, M., Rafie, K., Dorfmueller, H. C., Robinson, D. A. & van Aalten, D. M. F. 1 Feb 2014 In : Biochemical Journal. 457, 3, p. 497-502 6 p.

Research output: Contribution to journal › Article

The cyclic AMP phosphodiesterase RegA critically regulates encystation in social and pathogenic amoebas

Du, Q., Schilde, C., Birgersson, E., Chen, Z-H., McElroy, S. & Schaap, P. Feb 2014 In : Cellular Signalling. 26, 2, p. 453-459 7 p.

Research output: Contribution to journal › Article

Genome-wide dissection of the quorum sensing signalling pathway in Trypanosoma brucei

Mony, B. M., MacGregor, P., Ivens, A., Rojas, F., Cowton, A., Young, J., Horn, D. & Matthews, K. 30 Jan 2014 In : Nature. 505, 7485, p. 681-685 5 p.

Research output: Contribution to journal › Letter

In Vitro and In Vivo studies of trypanocidal activity of dietary isothiocyanates

Steverding, D., Michaels, S. & Read, K. D. 22 Jan 2014 In : Planta Medica.

Research output: Contribution to journal › Letter