Biological Chemistry and Drug Discovery

In vitro cell-free conversion of bacterial recombinant PrP to Prp(res) as a model for conversion

Kirby, L., Birkett, C. R., Rudyk, H., Gilbert, I. H. & Hope, J. Apr-2003 In : Journal of General Virology. 84, p. 1013-1020, 8 p.

Research output: Contribution to journal › Article

1-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: a new series of potent and selective triple reuptake inhibitors

Micheli, F. , Cavanni, P. , Arban, R. , Benedetti, R. , Bertani, B. , Bettati, M. , Bettelini, L. , Bonanomi, G. , Braggio, S. , Checchia, A. , Davalli, S. , Di Fabio, R. , Fazzolari, E. , Fontana, S. , Marchioro, C. , Minick, D. , Negri, M. , Oliosi, B. , Read, K. D. , Sartori, I. & 6 others Tedesco, G., Tarsi, L., Terreni, S., Visentini, F., Zocchi, A. & Zonzini, L. 25-Mar-2010 In : Journal of Medicinal Chemistry. 53, 6, p. 2534-2551, 18 p.

Research output: Contribution to journal › Article

14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells

Cotelle, V., Meek, S. E. M., Provan, F., Milne, F. C., Morrice, N. & MacKintosh, C. 2000 In : EMBO Journal. 19, 12, p. 2869-2876, 8 p.

Research output: Contribution to journal › Article

1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic alpha,beta-unsaturated aldehyde acrolein

Kelleher, M. O., McMahon, M., Eggleston, I. M., Dixon, M. J., Taguchi, K., Yamamoto, M. & Hayes, J. D. Oct-2009 In : Carcinogenesis. 30, 10, p. 1754-1762, 9 p.

Research output: Contribution to journal › Article

2,4-diaminopyrimidines as inhibitors of leishmanial and trypanosomal dihydrofolate reductase

Pez, D., Leal, I., Zuccotto, F., Boussard, C., Brun, R., Croft, S. L., Yardley, V., Perez, L. M. R., Pacanowska, D. G. & Gilbert, I. H. 3-Nov-2003 In : Bioorganic & Medicinal Chemistry. 11, 22, p. 4693-4711, 19 p.

Research output: Contribution to journal › Article

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: identification, stereochemistry and initial SAR

Wyatt, P. G., Allen, M. J., Borthwick, A. D., Davies, D. E., Exall, A. M., Hatley, R. J. D., Irving, W. R., Livermore, D. G., Miller, N. D., Nerozzi, F., Sollis, S. L. & Szardenings, A. K. May-2005 In : Bioorganic & Medicinal Chemistry Letters. 15, 10, p. 2579-2582, 4 p.

Research output: Contribution to journal › Article

31P solid-state MAS-NMR spectroscopy of the compounds that form in phosphate-bonded dental casting investment materials during setting

Scrimgeour, S. N., Chudek, J. A., Cowper, G. A. & Lloyd, C. H. 2007 In : Dental Materials. 23, 8, p. 934-943, 10 p.

Research output: Contribution to journal › Article

6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor

Micheli, F. , Cavanni, P. , Andreotti, D. , Arban, R. , Benedetti, R. , Bertani, B. , Bettati, M. , Bettelini, L. , Bonanomi, G. , Braggio, S. , Carletti, R. , Checchia, A. , Corsi, M. , Fazzolari, E. , Fontana, S. , Marchioro, C. , Merlo-Pich, E. , Negri, M. , Oliosi, B. , Ratti, E. & 11 others Read, K. D., Roscic, M., Sartori, I., Spada, S., Tedesco, G., Tarsi, L., Terreni, S., Visentini, F., Zocchi, A., Zonzini, L. & Di Fabio, R. 8-Jul-2010 In : Journal of Medicinal Chemistry. 53, 13, p. 4989-5001, 13 p.

Research output: Contribution to journal › Article

6-phosphogluconate dehydrogenase: A target for drugs in African trypanosomes

Hanau, S., Rinaldi, E., Dallocchio, F., Gilbert, I. H., Dardonville, C., Adams, M. J., Gover, S. & Barrett, M. P. Oct-2004 In : Current Topics in Medicinal Chemistry. 11, 19, p. 2639-2650, 12 p.

Research output: Contribution to journal › Scientific review

A comparative study of methylglyoxal metabolism in trypanosomatids

Greig, N., Wyllie, S., Patterson, S. & Fairlamb, A. H. Jan-2009 In : FEBS Journal. 276, 2, p. 376-386, 11 p.

Research output: Contribution to journal › Article