Discovery - University of Dundee - Online Publications

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Biological Chemistry and Drug Discovery

  1. Discovery and optimisation studies of antimalarial phenotypic hits

    Mital, A., Murugesan, D., Kaiser, M., Yeates, C. & Gilbert, I. H. 20 Oct 2015 In : European Journal of Medicinal Chemistry. 103, p. 530-538 9 p.

    Research output: Contribution to journalArticle

  2. Discovery of indoline-2-carboxamide derivatives as a new class of brain-penetrant inhibitors of Trypanosoma brucei

    Cleghorn, L. A. T., Albrecht, S., Stojanovski, L., Simeons, F. R. J., Norval, S., Kime, R., Collie, I. T., De Rycker, M., Campbell, L., Hallyburton, I., Frearson, J. A., Wyatt, P. G., Read, K. D. & Gilbert, I. H. 8 Oct 2015 In : Journal of Medicinal Chemistry. 58, 19, p. 7695-7706 12 p.

    Research output: Contribution to journalArticle

  3. Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis

    Damerow, S., Hoppe, C., Bandini, G., Zarnovican, P., Buettner, F. F. R., Ferguson, M. A. J. & Routier, F. H. Oct 2015 In : International Journal for Parasitology. 45, 12, p. 783-790 8 p.

    Research output: Contribution to journalArticle

  4. Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging

    Duce, S. L., Weir-McCall, J. R., Gandy, S. J., Matthew, S. Z., Cassidy, D. B., McCormick, L., Rauchhaus, P., Looker, H., Colhoun, H. M. & Houston, J. G. 18 Sep 2015 In : Cardiovascular Diabetology. 14, 11 p., 122

    Research output: Contribution to journalArticle

  5. A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development

    Mariappa, D., Selvan, N., Borodkin, V. S., Alonso , J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F. Sep 2015 In : Biochemical Journal. 470, 2, p. 255-262 8 p.

    Research output: Contribution to journalArticle

  6. Selective small molecule induced degradation of the BET bromodomain protein BRD4

    Zengerle, M., Chan, K-H. & Ciulli, A. 21 Aug 2015 In : ACS Chemical Biology. 10, 8, p. 1770-1777 8 p.

    Research output: Contribution to journalArticle

  7. Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity

    Sola, I., Castellà, S., Viayna, E., Galdeano, C., Taylor, M. C., Gbedema, S. Y., Pérez, B., Clos, M. V., Jones, D. C., Fairlamb, A. H., Wright, C. W., Kelly, J. M. & Muñoz-Torrero, D. 15 Aug 2015 In : Bioorganic & Medicinal Chemistry. 23, 16, p. 5156-5167 12 p.

    Research output: Contribution to journalArticle

  8. Bacillus anthracis meningitis during an outbreak of injectional anthrax, Scotland, UK

    Dewar, S., Weir-McCall, J. R., Batchelor, L., Cole, S. & Parcell, B. J. 1 Aug 2015 In : Clinical Microbiology and Infection. 21, 8, p. e49-e50 2 p.

    Research output: Contribution to journalArticle

  9. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

    Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. M. K. 1 Aug 2015 In : EMBO Reports. 16, 8, p. 939-954 16 p.

    Research output: Contribution to journalArticle

  10. Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates

    Graf, F. E., Baker, N., Munday, J. C., de Koning, H. P., Horn, D. & Mäser, P. Aug 2015 In : International Journal for Parasitology: Drugs and Drug Resistance. 5, 2, p. 65-68 4 p.

    Research output: Contribution to journalArticle

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