Biological Chemistry and Drug Discovery

Transcriptome analysis of skin reveals differences between atopic eczema cases stratified for filaggrin genotype

Brown, S., Cole, C., Irvine, A., Barton, G. & McLean, I. Apr-2012 In : British Journal of Dermatology. 166, 4, p. e26-e27, 2 p., O-30

Research output: Contribution to journal › Article

Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction

Buckley, D. L., Van Molle, I., Gareiss, P. C., Tae, H. S., Michel, J., Noblin, D. J., Jorgensen, W. L., Ciulli, A. & Crews, C. M. 14-Mar-2012 In : Journal of the American Chemical Society. 134, 10, p. 4465-4468, 4 p.

Research output: Contribution to journal › Article

A quantitative spatial proteomics analysis of proteome turnover in human cells

Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I. 1-Mar-2012 In : Molecular & Cellular Proteomics. 11, 3

Research output: Contribution to journal › Article

Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M. D. Mar-2012 In : Chemical Biology & Drug Design. 79, 3, p. 270-278, 9 p.

Research output: Contribution to journal › Article

Conserved signal peptide recognition systems across the prokaryotic domains

Coulthurst, S. J., Dawson, A., Hunter, W. N. & Sargent, F. 28-Feb-2012 In : Biochemistry. 51, 8, p. 1678-1686, 9 p.

Research output: Contribution to journal › Article

Synergy of peptide and sugar in O-GlcNAcase substrate recognition

Schimpl, M., Borodkin, V. S., Gray, L. J. & van Aalten, D. M. F. 24-Feb-2012 In : Chemistry & Biology. 19, 2, p. 173-178, 6 p.

Research output: Contribution to journal › Article

Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism

Daneshvar, H., Wyllie, S., Phillips, S., Hagan, P. & Burchmore, R. 16-Feb-2012 In : Journal of Proteomics. 75, 5, p. 1463-1471, 9 p.

Research output: Contribution to journal › Article

Identification and localisation of the NB-LRR gene family within the potato genome

Jupe, F., Pritchard, L., Etherington, G. J., MacKenzie, K., Cock, P. J. A., Wright, F., Sharma, S. K., Bolser, D., Bryan, G. J., Jones, J. D. G. & Hein, I. 15-Feb-2012 In : BMC Genomics. 13, p. -, 14 p., 75

Research output: Contribution to journal › Article

Quinol derivatives as potential trypanocidal agents

Capes, A., Patterson, S., Wyllie, S., Hallyburton, I., Collie, I. T., McCarroll, A. J., Stevens, M. F. G., Frearson, J. A., Wyatt, P. G., Fairlamb, A. H. & Gilbert, I. H. 15-Feb-2012 In : Bioorganic & Medicinal Chemistry. 20, 4, p. 1607-1615, 9 p.

Research output: Contribution to journal › Article

Infectious disease: Genomics decodes drug action

Fairlamb, A. H. 9-Feb-2012 In : Nature. 482, 7384, p. 167-169, 3 p.

Research output: Contribution to journal › Editorial