Discovery - University of Dundee - Online Publications

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Biological Chemistry and Drug Discovery

  1. Development and applications of biosensor assays for fragment screening of wild-type GPCRs

    Hopkins Navratilova, I. & Fagge, T. 2015 In : European Pharmaceutical Review. 20, 6, p. 29-31 3 p.

    Research output: Contribution to journalArticle

  2. ENTH and ANTH domain proteins participate in AP2-independent clathrin-mediated endocytosis

    Manna, P. T., Gadelha, C., Puttick, A. E. & Field, M. C. 2015 In : Journal of Cell Science. 128, 11, p. 2130-2142 13 p.

    Research output: Contribution to journalArticle

  3. Identification of a glycosylphosphatidylinositol anchor-modifying β1-3 galactosyltransferase in Trypanosoma brucei

    Izquierdo, L., Acosta-Serrano, A., Mehlert, A. & Ferguson, M. A. J. 2015 In : Glycobiology. 25, 4, p. 438-447 50 p.

    Research output: Contribution to journalArticle

  4. New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource

    Peña, I. , Pilar Manzano, M. , Cantizani, J. , Kessler, A. , Alonso-Padilla, J. , Bardera, A. I. , Alvarez, E. , Colmenarejo, G. , Cotillo, I. , Roquero, I. , de Dios-Anton, F. , Barroso, V. , Rodriguez, A. , Gray, D. W. , Navarro, M. , Kumar, V. , Sherstnev, A. , Drewry, D. H. , Brown, J. R. , Fiandor, J. M. & 1 others Julio Martin, J. 2015 In : Scientific Reports. 5, 12 p., 8771

    Research output: Contribution to journalArticle

  5. New synthetic routes to Triazolo-benzodiazepine analogues: expanding the scope of the bump-and-hole approach for selective Bromo and Extra-Terminal (BET) bromodomain inhibition

    Baud, M. G. J., Lin-Shiao, E., Zengerle, M., Tallant, C. & Ciulli, A. 2015 In : Journal of Medicinal Chemistry. 9 p.

    Research output: Contribution to journalArticle

  6. Optimization of inhibitors of Mycobacterium tuberculosis pantothenate synthetase based on group efficiency analysis

    Hung, A. W., Silvestre, H. L., Wen, S., George, G. P. C., Boland, J., Blundell, T. L., Ciulli, A. & Abell, C. 2015 In : ChemMedChem. 6 p.

    Research output: Contribution to journalArticle

  7. Surface plasmon resonance analysis of seven-transmembrane receptors

    Aristotelous, T., Hopkins, A. L. & Navratilova, I. 2015 Membrane proteins—production and functional characterization. Shukla, A. K. (ed.). Academic Press, p. 499-525 27 p. (Methods in Enzymology; vol. 556)

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  8. The importance of triaging in determining the quality of output from high-throughput screening

    Jones, P., McElroy, S., Morrison, A. & Pannifer, A. 2015 In : Future Medicinal Chemistry. 7, 14, p. 1847-1852 6 p.

    Research output: Contribution to journalComment/debate

  9. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

    Mudie, S., Bandarra, D., Batie, M., Biddlestone, J., Moniz, S., Ortmann, B., Shmakova, A. & Rocha, S. 15 Dec 2014 In : Cell Cycle. 13, 24, p. 3878-3891 14 p.

    Research output: Contribution to journalArticle

  10. O-GlcNAcase: promiscuous hexosaminidase or key regulator of O-GlcNAc signalling?

    Alonso , J., Schimpl, M. & van Aalten, D. M. F. 12 Dec 2014 In : Journal of Biological Chemistry. 289, 50, p. 34433-34439 7 p.

    Research output: Contribution to journalArticle

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