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  1. The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution

    Bowman, A., Hammond, C. M., Stirling, A., Ward, R., Shang, W., El-Mkami, H., Robinson, D. A., Svergun, D. I., Norman, D. G., Owen-Hughes, T. & Singh, V. 2014 In : Nucleic Acids Research. 42, 9, p. 6038-6051 13 p.

    Research output: Contribution to journalArticle

  2. The role of ligand efficiency metrics in drug discovery

    Hopkins, A. L., Keserü, G. M., Leeson, P. D., Rees, D. C. & Reynolds, C. H. 2014 In : Nature Reviews Drug Discovery. 13, 2, p. 105-121 17 p.

    Research output: Contribution to journalArticle

  3. Touching from a distance: evolution of interplay between the nuclear pore complex, nuclear basket, and the mitotic spindle

    Holden, J. M., Koreny, L., Kelly, S., Chait, B. T., Rout, M. P., Field, M. C. & Obado, S. O. 2014 In : Nucleus. 5, 4

    Research output: Contribution to journalArticle

  4. Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

    Glover, L., Hutchinson, S., Alsford, S., McCulloch, R., Field, M. C. & Horn, D. Dec 2013 In : Cellular Microbiology. 15, 12, p. 1984-1993 10 p.

    Research output: Contribution to journalArticle

  5. Fragment-based hit identification: thinking in 3D

    Morley, A. D., Pugliese, A., Birchall, K., Bower, J., Brennan, P., Brown, N., Chapman, T., Drysdale, M., Gilbert, I. H., Hoelder, S., Jordan, A., Ley, S. V., Merritt, A., Miller, D., Swarbrick, M. E. & Wyatt, P. G. Dec 2013 In : Drug Discovery Today. 18, 23-24, p. 1221-1227 7 p.

    Research output: Contribution to journalArticle

  6. Structural basis for type VI secreted peptidoglycan DL-endopeptidase function, specificity and neutralization in Serratia marcescens

    Srikannathasan, V., English, G., Bui, N. K., Trunk, K., O'Rourke, P. E. F., Rao, V. A., Vollmer, W., Coulthurst, S. J. & Hunter, W. N. Dec 2013 In : Acta Crystallographica Section D: Biological Crystallography. 69, 12, p. 2468-2482 15 p.

    Research output: Contribution to journalArticle

  7. Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain

    Ferguson, F. M., Fedorov, O., Chaikuad, A., Philpott, M., Muniz, J. R. C., Felletar, I., von Delft, F., Heightman, T., Knapp, S., Abell, C. & Ciulli, A. Dec 2013 In : Journal of Medicinal Chemistry. 56, 24, p. 10183-10187 5 p.

    Research output: Contribution to journalArticle

  8. Two high-resolution structures of the human E3 ubiquitin ligase Siah1

    Rimsa, V., Eadsforth, T. C. & Hunter, W. N. Dec 2013 In : Acta Crystallographica F-Structural Biology and Crystallization Communications. 69, 12, p. 1339-1343 5 p.

    Research output: Contribution to journalArticle

  9. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

    Brown, S. J. , Madhok, V. B. & 32 others Saunders, S. P., Goh, C. S. M., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G. Nov 2013 In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

    Research output: Contribution to journalArticle

  10. Construction of reference chromosome-scale pseudomolecules for potato: integrating the potato genome with genetic and physical maps

    Sharma, S. K. , Bolser, D. , de Boer, J. , Sønderkær, M. , Amoros, W. , Carboni, M. F. , D'Ambrosio, J. M. , de la Cruz, G. , Di Genova, A. , Douches, D. S. , Eguiluz, M. , Guo, X. , Guzman, F. , Hackett, C. A. , Hamilton, J. P. , Li, G. , Li, Y. , Lozano, R. , Maass, A. , Marshall, D. & 25 others Martinez, D., McLean, K., Mejía, N., Milne, L., Munive, S., Nagy, I., Ponce, O., Ramirez, M., Simon, R., Thomson, S. J., Torres, Y., Waugh, R., Zhang, Z., Huang, S., Visser, R. G. F., Bachem, C. W. B., Sagredo, B., Feingold, S. E., Orjeda, G., Veilleux, R. E., Bonierbale, M., Jacobs, J. M. E., Milbourne, D., Martin, D. M. A. & Bryan, G. J. Nov 2013 In : G3 : Genes, Genomes, Genetics. 3, 11, p. 2031-2047 17 p.

    Research output: Contribution to journalArticle

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