Discovery - University of Dundee - Online Publications

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Biological Chemistry and Drug Discovery

  1. DNA breaks as triggers for antigenic variation in African trypanosomes

    Alsford, S., Horn, D. & Glover, L. 2009 In : Genome Biology. 10, 6, 4 p., ARTN 223

    Research output: Contribution to journalReview article

  2. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity

    Howard, S. , Berdini, V. , Boulstridge, J. A. , Carr, M. G. , Cross, D. M. , Curry, J. , Devine, L. A. , Early, T. R. , Fazal, L. , Gill, A. L. , Heathcote, M. , Maman, S. , Matthews, J. E. , McMenamin, R. L. , Navarro, E. F. , O'Brien, M. A. , O'Reilly, M. , Rees, D. C. , Reule, M. & 4 others Tisi, D., Williams, G., Vinković, M. & Wyatt, P. G. 2009 In : Journal of Medicinal Chemistry. 52, 2, p. 379-88 10 p.

    Research output: Contribution to journalArticle

  3. Fragment-based drug discovery in academia: Experiences from a tuberculosis programme

    Heikkila, T. J., Surade, S., Silvestre, H. L., Dias, M. V. B., Ciulli, A., Bromfield, K., Scott, D., Howard, N., Wen, S., Wei, A. H., Osborne, D., Abell, C. & Blundell, T. L. 2009 From Molecules to Medicines: Structure of Biological Macromolecules and Its Relevance in Combating New Diseases and Bioterrorism. Sussman, J. L. & Spadon, P. (eds.). Springer Netherlands, p. 21-36 16 p. (NATO Science for Peace and Security Series A: Chemistry and Biology)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  4. Glycosylphosphatidylinositol anchors

    Ferguson, M. A. J., Kinoshita, T. & Hart, G. W. 2009 Essentials of glycobiology. Varki, A. (ed.). 2nd ed. Cold Spring Harbor: Cold Spring Harbor Laboratory Press, p. 143-162 20 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  5. How does human O-Glcnacase recognize O-Glcnacylated protein substrates?

    Schimpl, M., Borodkin, V. S. & Van Aalten, D. M. F. 2009 In : Glycobiology. 19, 11, p. 1369-1369 1 p., 272

    Research output: Contribution to journalMeeting abstract

  6. Identification of nucleolar associated chromatin loci reveals clues for nuclear architecture

    van Koningsbruggen, S., Martin, D. M. A., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I. 2009 In : Cellular Oncology. 31, 2, p. 105-106 2 p., O16

    Research output: Contribution to journalBook/Film/Article review

  7. Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases

    Martin, D. M. A., Miranda-Saavedra, D. & Barton, G. J. 2009 In : Nucleic Acids Research. 37, Suppl. 1. Database issue, p. D244-D250 7 p.

    Research output: Contribution to journalArticle

  8. Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites

    Baliani, A., Peal, V., Gros, L., Brun, R., Kaiser, M., Barrett, M. P. & Gilbert, I. H. 2009 In : Organic and Biomolecular Chemistry. 7, 6, p. 1154-1166 13 p.

    Research output: Contribution to journalArticle

  9. Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold

    Dixon, M. J., Nathubhai, A., Andersen, O. A., van Aalten, D. M. F. & Eggleston, I. M. 2009 In : Organic and Biomolecular Chemistry. 7, 2, p. 259-268 10 p.

    Research output: Contribution to journalArticle

  10. Specificity and mechanism of Acinetobacter baumanii nicotinamidase: implications for activation of the front-line tuberculosis drug pyrazinamide

    Fyfe, P. K., Rao, V. A., Zemla, A., Cameron, S. & Hunter, W. N. 2009 In : Angewandte Chemie International Edition. 48, 48, p. 9176-9179 4 p.

    Research output: Contribution to journalArticle

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