Discovery - University of Dundee - Online Publications

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Biological Chemistry and Drug Discovery

  1. SPPS of the natural product chitinase inhibitor argifin: library generation and biological evaluation

    Dixon, M. J., Andersen, O. A., van Aalten, D. M. F. & Eggleston, I. M. 2009 Peptides for youth: the proceedings of the 20th American Peptide Symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). New York: Springer , p. 143-144 2 p. (Advances in experimental medicine and biology; vol. 611)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. Synthesis and structure-based dissection of cyclic peptide chitinase inhibitors: new leads for antifungal and anti-inflammatory drugs

    Dixon, M. J., Nathubhai, A., Andersen, O. A., van Aalten, D. M. F. & Eggleston, I. M. 2009 Peptides for youth: the proceedings of the 20th American Peptide Symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). New York: Springer , p. 525-526 2 p. (Advances in experimental medicine and biology; vol. 611)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  3. The GlcNAc-PI de-N-acetylase: structure, function, and activity

    Urbaniak, M. D. & Ferguson, M. A. J. 2009 In : Enzymes. 26, p. 49-64 16 p.

    Research output: Contribution to journalArticle

  4. Specificity and reactivity in menaquinone biosynthesis: the structure of Escherichia coli MenD (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase)

    Dawson, A., Fyfe, P. K. & Hunter, W. N. 31 Dec 2008 In : Journal of Molecular Biology. 384, 5, p. 1353-1368 16 p.

    Research output: Contribution to journalArticle

  5. Inhibitors of tubulin assembly identified through screening a compound library

    Morgan, R. E., Ahn, S., Nzimiro, S., Fotie, J., Phelps, M. A., Cotrill, J., Yakovich, A. J., Sackett, D. L., Dalton, J. T. & Werbovetz, K. A. Dec 2008 In : Chemical Biology & Drug Design. 72, 6, p. 513-524 12 p.

    Research output: Contribution to journalArticle

  6. Structure of the OSR1 kinase, a hypertension drug target

    Villa, F., Deak, M., Alessi, D. R. & van Aalten, D. M. F. Dec 2008 In : Proteins: Structure, Function, and Bioinformatics. 73, 4, p. 1082-1087 6 p.

    Research output: Contribution to journalArticle

  7. A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

    Towler, M. C., Fogarty, S., Hawley, S. A., Pan, D. A., Martin, D. M. A., Morrice, N. A., McCarthy, A., Galardo, M. N., Meroni, S. B., Cigorraga, S. B., Ashworth, A., Sakamoto, K. & Hardie, D. G. 15 Nov 2008 In : Biochemical Journal. 416, 1, p. 1-14 14 p.

    Research output: Contribution to journalArticle

  8. Structure of staphylococcus aureus EsxA suggests a contribution to virulence by action as a transport chaperone and/or adaptor protein

    Sundaramoorthy, R., Fyfe, P. K. & Hunter, W. N. 14 Nov 2008 In : Journal of Molecular Biology. 383, 3, p. 603-614 12 p.

    Research output: Contribution to journalArticle

  9. Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.

    Ciulli, A., Scott, D. E., Ando, M., Reyes, F., Saldanha, S. A., Tuck, K. L., Chirgadze, D. Y., Blundell, T. L. & Abell, C. 3 Nov 2008 In : ChemBioChem. 9, 16, p. 2606-2611 6 p.

    Research output: Contribution to journalArticle

  10. ATP-dependent ligases in trypanothione biosynthesis - kinetics of catalysis and inhibition by phosphinic acid pseudopeptides

    Oza, S. L., Chen, S., Wyllie, S., Coward, J. K. & Fairlamb, A. H. Nov 2008 In : FEBS Journal. 275, 21, p. 5408-5421 14 p.

    Research output: Contribution to journalArticle

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