Discovery - University of Dundee - Online Publications

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Biological Chemistry and Drug Discovery

  1. Specificity and reactivity in menaquinone biosynthesis: the structure of Escherichia coli MenD (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase)

    Dawson, A., Fyfe, P. K. & Hunter, W. N. 31 Dec 2008 In : Journal of Molecular Biology. 384, 5, p. 1353-1368 16 p.

    Research output: Contribution to journalArticle

  2. Inhibitors of tubulin assembly identified through screening a compound library

    Morgan, R. E., Ahn, S., Nzimiro, S., Fotie, J., Phelps, M. A., Cotrill, J., Yakovich, A. J., Sackett, D. L., Dalton, J. T. & Werbovetz, K. A. Dec 2008 In : Chemical Biology & Drug Design. 72, 6, p. 513-524 12 p.

    Research output: Contribution to journalArticle

  3. Structure of the OSR1 kinase, a hypertension drug target

    Villa, F., Deak, M., Alessi, D. R. & van Aalten, D. M. F. Dec 2008 In : Proteins: Structure, Function, and Bioinformatics. 73, 4, p. 1082-1087 6 p.

    Research output: Contribution to journalArticle

  4. A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

    Towler, M. C., Fogarty, S., Hawley, S. A., Pan, D. A., Martin, D. M. A., Morrice, N. A., McCarthy, A., Galardo, M. N., Meroni, S. B., Cigorraga, S. B., Ashworth, A., Sakamoto, K. & Hardie, D. G. 15 Nov 2008 In : Biochemical Journal. 416, 1, p. 1-14 14 p.

    Research output: Contribution to journalArticle

  5. Structure of staphylococcus aureus EsxA suggests a contribution to virulence by action as a transport chaperone and/or adaptor protein

    Sundaramoorthy, R., Fyfe, P. K. & Hunter, W. N. 14 Nov 2008 In : Journal of Molecular Biology. 383, 3, p. 603-614 12 p.

    Research output: Contribution to journalArticle

  6. Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.

    Ciulli, A., Scott, D. E., Ando, M., Reyes, F., Saldanha, S. A., Tuck, K. L., Chirgadze, D. Y., Blundell, T. L. & Abell, C. 3 Nov 2008 In : ChemBioChem. 9, 16, p. 2606-2611 6 p.

    Research output: Contribution to journalArticle

  7. ATP-dependent ligases in trypanothione biosynthesis - kinetics of catalysis and inhibition by phosphinic acid pseudopeptides

    Oza, S. L., Chen, S., Wyllie, S., Coward, J. K. & Fairlamb, A. H. Nov 2008 In : FEBS Journal. 275, 21, p. 5408-5421 14 p.

    Research output: Contribution to journalArticle

  8. GPIomics: Global Analysis of Glycosylphosphatidylinositol (GPI)-Anchored Molecules of Trypanosoma cruzi by Tandem Mass Spectrometry

    Nakayasu, E. S., Yashunsky, D. V., Nohara, L. L., Torrecilhas, A. C. T., Nikolaev, A. V. & Almeida, I. C. Nov 2008 In : Glycobiology. 18, 11, p. 974-974 1 p., 140

    Research output: Contribution to journalBook/Film/Article review

  9. Network pharmacology: the next paradigm in drug discovery

    Hopkins, A. L. Nov 2008 In : Nature Chemical Biology. 4, 11, p. 682-690 9 p.

    Research output: Contribution to journalScientific review

  10. Sugar nucleotide metabolism and compartmentation in Trypanosoma brucei: new insights from UDP-GlcNAc and UDP-Glc biosynthesis

    Marino, K., Guther, M. L. S. & Ferguson, M. Nov 2008 In : Glycobiology. 18, 11, p. 946-946 1 p.

    Research output: Contribution to journalMeeting abstract

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