Discovery - University of Dundee - Online Publications

Library & Learning Centre

Biological Chemistry and Drug Discovery

  1. Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

    Alsford, S. & Horn, D. Sep 2008 In : Molecular and Biochemical Parasitology. 161, 1, p. 76-79 4 p.

    Research output: Contribution to journalArticle

  2. Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway

    Signorell, A., Rauch, M., Jelk, J., Ferguson, M. A. J. & Buetikofer, P. 29 Aug 2008 In : Journal of Biological Chemistry. 283, 35, p. 23636-23644 9 p.

    Research output: Contribution to journalArticle

  3. Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design

    Wyatt, P. G. , Woodhead, A. J. , Berdini, V. , Boulstridge, J. A. , Carr, M. G. , Cross, D. M. , Davis, D. J. , Devine, L. A. , Early, T. R. , Feltell, R. E. , Lewis, E. J. , McMenamin, R. L. , Navarro, E. F. , O'Brien, M. A. , O'Reilly, M. , Reule, M. , Saxty, G. , Seavers, L. C. A. , Smith, D-M. , Squires, M. S. & 3 others Trewartha, G., Walker, M. T. & Woolford, A. J. -A. 28 Aug 2008 In : Journal of Medicinal Chemistry. 51, 16, p. 4986-4999 14 p.

    Research output: Contribution to journalArticle

  4. Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death

    Pathak, S., Dorfmueller, H. C., Borodkin, V. S. & van Aalten, D. M. F. 25 Aug 2008 In : Chemistry & Biology. 15, 8, p. 799-807 9 p.

    Research output: Contribution to journalArticle

  5. COMP 90-The trouble with translating information into medicines: strategies for embracing serendipity and uncertainty

    Hopkins, A. L. 17 Aug 2008 In : Abstracts of Papers of the American Chemical Society. 236, p. - 1 p.

    Research output: Contribution to journalBook/Film/Article review

  6. Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues

    Urbaniak, M. D., Crossman, A. & Ferguson, M. A. J. Aug 2008 In : Chemical Biology & Drug Design. 72, 2, p. 127-132 6 p.

    Research output: Contribution to journalArticle

  7. Synthesis of cyclic peptide chitinase inhibitors: natural products,with chemotherapeutic potential

    Dixon, M., Nathubhai, A., Andersen, O., van Aalten, D. & Eggleston, I. Aug 2008 In : Journal of Peptide Science. 14, S1, p. 13-13 1 p., S02-4

    Research output: Contribution to journalBook/Film/Article review

  8. Synthetic approaches to cyclic peptide natural products as chitinase inhibitors

    Dixon, M., Giuntini, F., Nathubhai, A., Andersen, O., van Aalten, D. & Eggleston, I. Aug 2008 In : Journal of Peptide Science. 14, S1, p. 55-55 1 p., P10102-031

    Research output: Contribution to journalBook/Film/Article review

  9. Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes

    Kawahara, T., Siegel, T. N., Ingram, A. K., Alsford, S., Cross, G. A. M. & Horn, D. Aug 2008 In : Molecular Microbiology. 69, 4, p. 1054-1068 15 p.

    Research output: Contribution to journalArticle

Find Research Units in Discovery

Library & Learning Centre

Contact | Accessibility | Policy