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Biological Chemistry and Drug Discovery

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  1. Picking pockets to fuel antimicrobial drug discovery

    Hunter, W. N. Nov 2007 In : Biochemical Society Transactions. 35, p. 980-984 5 p.

    Research output: Contribution to journalArticle

  2. Quinuclidine derivatives as potential antiparasitics

    Cammerer, S. B., Jimenez, C., Jones, S., Gros, L., Lorente, S. O., Rodrigues, C., Rodrigues, J. C. F., Caldera, A., Perez, L. M. R., da Souza, W., Kaiser, M., Brun, R., Urbina, J. A., Pacanowska, D. G. & Gilbert, I. H. Nov 2007 In : Antimicrobial Agents and Chemotherapy. 51, 11, p. 4049-4061 13 p.

    Research output: Contribution to journalArticle

  3. Structure of Staphylococcus aureus 1,4-dihydroxy-2-naphthoyl-CoA synthase (MenB) in complex with acetoacetyl-CoA

    Ulaganathan, V., Agacan, M. F., Buetow, L., Tulloch, L. B. & Hunter, W. N. Nov 2007 In : Acta Crystallographica F-Structural Biology and Crystallization Communications. 63, p. 908-913 6 p.

    Research output: Contribution to journalArticle

  4. The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphatesynthase, an essential enzyme, provides a platform for drug discovery

    Buetow, L., Brown, A. C., Parish, T. & Hunter, W. N. 23 Oct 2007 In : BMC Structural Biology. 7, p. - 11 p.68

    Research output: Contribution to journalArticle

  5. Mechanistic insights into the cure of prion disease by novel antiprion compounds

    Webb, S., Lekishvili, T., Loeschner, C., Sellarajah, S., Prelli, F., Wisniewski, T., Gilbert, I. H. & Brown, D. R. Oct 2007 In : Journal of Virology. 81, 19, p. 10729-10741 13 p.

    Research output: Contribution to journalArticle

  6. Network pharmacology

    Hopkins, A. L. Oct 2007 In : Nature Biotechnology. 25, 10, p. 1110-1111 2 p.

    Research output: Contribution to journalArticle

  7. The de novo synthesis of GDP-fucose is essential for flagellar adhesion and cell growth in trypanosoma brucei

    Turnock, D. C., Izquierdo, L. & Ferguson, M. A. J. Sep 2007 In : Journal of Biological Chemistry. 282, 39, p. 28853-28863 11 p.

    Research output: Contribution to journalArticle

  8. Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity

    Byres, E., Alphey, M. S., Smith, T. K. & Hunter, W. N. 10 Aug 2007 In : Journal of Molecular Biology. 371, 2, p. 540-553 14 p.

    Research output: Contribution to journalArticle

  9. 31P solid-state MAS-NMR spectroscopy of the compounds that form in phosphate-bonded dental casting investment materials during setting

    Scrimgeour, S. N., Chudek, J. A., Cowper, G. A. & Lloyd, C. H. Aug 2007 In : Dental Materials. 23, 8, p. 934-943 10 p.

    Research output: Contribution to journalArticle

  10. Sugar nucleotide pools of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major

    Turnock, D. C. & Ferguson, M. A. J. Aug 2007 In : Eukaryotic Cell. 6, 8, p. 1450-1463 14 p.

    Research output: Contribution to journalScientific review

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