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Biological Chemistry and Drug Discovery

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  1. Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling

    Atrih, A., Mudaliar, M. A. V., Zakikhani, P., Lamont, D. J., Huang, J. T-J., Bray, S. E., Barton, G., Fleming, S. & Nabi, G. 2014 In : British Journal of Cancer. 110, 6, p. 1622-1633 12 p.

    Research output: Contribution to journalArticle

  2. Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis

    Arora, K., Ochoa-Montaño, B., Tsang, P. S., Blundell, T. L., Dawes, S. S., Mizrahi, V., Bayliss, T., Mackenzie, C. J., Cleghorn, L. A. T., Ray, P. C., Wyatt, P. G., Uh, E., Lee, J., Barry, C. E. & Boshoff, H. I. 2014 In : Antimicrobial Agents and Chemotherapy. 12 p.

    Research output: Contribution to journalArticle

  3. Standardizing biochemistry dataset for medical research

    Bonney, W., Doney, A. & Jefferson, E. 2014 HEALTHINF 2014 - 7th International Conference on Health Informatics, Proceedings; Part of 7th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2014. p. 205-210 6 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  4. Structure-based virtual screening for the identification of RNA-binding ligands

    Daldrop, P. & Brenk, R. 2014 Therapeutic applications of ribozymes and riboswitches: methods and protocols. Lafontaine, D. & Dubé, A. (eds.). Humana Press, p. 127-139 13 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  5. The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution

    Bowman, A., Hammond, C. M., Stirling, A., Ward, R., Shang, W., El-Mkami, H., Robinson, D. A., Svergun, D. I., Norman, D. G. & Owen-Hughes, T. 2014 In : Nucleic Acids Research. 42, 9, p. 6038-6051 13 p.

    Research output: Contribution to journalArticle

  6. The role of ligand efficiency metrics in drug discovery

    Hopkins, A. L., Keserü, G. M., Leeson, P. D., Rees, D. C. & Reynolds, C. H. 2014 In : Nature Reviews Drug Discovery. 13, 2, p. 105-121 17 p.

    Research output: Contribution to journalArticle

  7. Touching from a distance: evolution of interplay between the nuclear pore complex, nuclear basket, and the mitotic spindle

    Holden, J. M., Koreny, L., Kelly, S., Chait, B. T., Rout, M. P., Field, M. C. & Obado, S. O. 2014 In : Nucleus. 5, 4

    Research output: Contribution to journalArticle

  8. TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

    Fairlamb, A. H. , Ferguson, M. A. J. & 39 others Shameer, S., Logan-Klumpler, F. J., Vinson, F., Cottret, L., Merlet, B., Achcar, F., Boshart, M., Berriman, M., Breitling, R., Bringaud, F., Bütikofer, P., Cattanach, A. M., Bannerman-Chukualim, B., Creek, D. J., Crouch, K., de Koning, H. P., Denise, H., Ebikeme, C., Ginger, M. L., Hertz-Fowler, C., Kerkhoven, E. J., Mäser, P., Michels, P. A. M., Nayak, A., Nes, D. W., Nolan, D. P., Olsen, C., Silva-Franco, F., Smith, T. K., Taylor, M. C., Tielens, A. G. M., Urbaniak, M. D., van Hellemond, J. J., Vincent, I. M., Wilkinson, S. R., Wyllie, S., Opperdoes, F. R., Barrett, M. P. & Jourdan, F. 2014 In : Nucleic Acids Research. 8 p.

    Research output: Contribution to journalArticle

  9. Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control

    Glover, L., Hutchinson, S., Alsford, S., McCulloch, R., Field, M. C. & Horn, D. Dec 2013 In : Cellular Microbiology. 15, 12, p. 1984-1993 10 p.

    Research output: Contribution to journalArticle

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