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  1. Global Quantitative SILAC Phosphoproteomics Reveals Differential Phosphorylation Is Widespread between the Procyclic and Bloodstream Form Lifecycle Stages of Trypanosoma brucei

    Urbaniak, M. D., Martin, D. M. A. & Ferguson, M. A. J. 3-May-2013 In : Journal of Proteome Research. 12, 5, p. 2233-2244, 12 p.

    Research output: Contribution to journalArticle

  2. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

    Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P. 1-May-2013 In : Biochemical Journal. 451, 3, p. 427-437, 11 p.

    Research output: Contribution to journalArticle

  3. Improved sperm function / activity

    Barratt, C. & Wyatt, P. 18-Apr-2013 WO2013054111 A1

    Research output: Patent

  4. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

    Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3-Apr-2013 In : EMBO Journal. 32, 7, p. 1008-22, 15 p.

    Research output: Contribution to journalArticle

  5. The architecture of EssB, an integral membrane component of the type VII secretion system

    Zoltner, M., Norman, D. G., Fyfe, P. K., El Mkami, H., Palmer, T. & Hunter, W. N. 2-Apr-2013 In : Structure. 21, 4, p. 595-603, 9 p.

    Research output: Contribution to journalArticle

  6. The importance of the N-terminus of T7 endonuclease I in the interaction with DNA junctions

    Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J. 23-Jan-2013 In : Journal of Molecular Biology. 425, 2, p. 395-410, 16 p.

    Research output: Contribution to journalArticle

  7. Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment

    Zoltner, M., Fyfe, P. K., Palmer, T. & Hunter, W. N. 15-Jan-2013 In : Biochemical Journal. 449, 2, p. 469-477, 9 p.

    Research output: Contribution to journalArticle

  8. PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

    Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C. 15-Jan-2013 In : Journal of Immunology. 190, 2, p. 565-77, 13 p.

    Research output: Contribution to journalArticle

  9. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  10. A sweet TET-a-tete-synergy of TET proteins and O-GlcNAc transferase in transcription

    Mariappa, D., Pathak, S. & van Aalten, D. M. F. 2013 In : EMBO Journal. 32, 5, p. 612-613, 2 p.

    Research output: Contribution to journalEditorial

  11. Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.

    De Rycker, M., Hallyburton, I., Thomas, J., Campbell, L., Wyllie, S., Joshi, D., Cameron, S., Gilbert, I. H., Wyatt, P. G., Frearson, J. A., Fairlamb, A. H. & Gray, D. W. 2013 In : Antimicrobial Agents and Chemotherapy.

    Research output: Contribution to journalArticle

  12. Electromechanical Behaviour of Nafion-based Soft Actuators

    Naji, L., Chudek, J. A., Abel, E. W. & Baker, R. T. 2013 In : Journal of Physical Chemistry B. 1, 19, p. 2502-2514, 13 p.

    Research output: Contribution to journalArticle

  13. Proteome wide purification and identification of O-GlcNAc-modified proteins using click chemistry and mass spectrometry

    Hahne, H., Sobotzki, N., Nyberg, T., Helm, D., Borodkin, V. S., van Aalten, D. M. F., Agnew, B. & Kuster, B. 2013 In : Journal of Proteome Research. 12, 2, p. 927-936, 10 p.

    Research output: Contribution to journalArticle

  14. Regulation of the cardiac Na(+) pump by palmitoylation of its catalytic and regulatory subunits

    Howie, J., Tulloch, L. B., Shattock, M. J. & Fuller, W. 2013 In : Biochemical Society Transactions. 41, 1, p. 95-100, 6 p.

    Research output: Contribution to journalArticle

  15. Structure of Pseudomonas aeruginosa inosine 5-monophosphate dehydrogenase

    Rao, V. A., Shepherd, S. M., Owen, R. & Hunter, W. N. 2013 In : Acta Crystallographica F-Structural Biology and Crystallization Communications. 69, 3, p. 243-247, 5 p.

    Research output: Contribution to journalArticle

  16. The plasticity of a structural motif in RNA: Structural polymorphism of a kink turn as a function of its environment

    Daldrop, P. & Lilley, D. M. J. 2013 In : RNA: a Publication of the RNA Society. 19, 3, p. 357-364, 8 p.

    Research output: Contribution to journalArticle

  17. Automated design of ligands to polypharmacological profiles

    Gilbert, I. H. & 20 others Besnard, J., Ruda, G. F., Setola, V., Abecassis, K., Rodriguiz, R. M., Huang, X-P., Norval, S., Sassano, M. F., Shin, A. I., Webster, L. A., Simeons, F. R. C., Stojanovski, L., Prat, A., Seidah, N. G., Constam, D. B., Bickerton, G. R., Read, K. D., Wetsel, W. C., Roth, B. L. & Hopkins, A. L. 13-Dec-2012 In : Nature. 492, 7428, p. 215-+, 8 p.

    Research output: Contribution to journalArticle

  18. Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P-3-dependent mechanisms leading to resistance to PDK1 inhibitors

    Najafov, A., Shpiro, N. & Alessi, D. R. Dec-2012 In : Biochemical Journal. 448, 2, p. 285-295, 11 p.

    Research output: Contribution to journalArticle

  19. A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes

    De Rycker, M., O'Neill, S., Joshi, D., Campbell, L., Gray, D. W. & Fairlamb, A. H. 29-Nov-2012 In : PLoS Neglected Tropical Diseases. 6, 11, p. e1932

    Research output: Contribution to journalArticle

  20. Structural plasticity of histones H3–H4 facilitates their allosteric exchange between RbAp48 and ASF1

    Zhang, W., Yyl, M., Ward, R., Sobott, F., Maman, J., Murthy, A., Watson, A., Fedorov, O., Bowman, A., Owen-Hughes, T., El Mkami, H., Murzina, N., Norman, D. G. & Laue, E. 25-Nov-2012 In : Nature Structural & Molecular Biology. 20, 1, p. 29-35

    Research output: Contribution to journalArticle

  21. Small-molecule inhibitors of the interaction between the E3 ligase VHL and HIF1α

    Buckley, D. L., Gustafson, J. L., Van-Molle, I., Roth, A. G., Tae, H. S., Gareiss, P. C., Jorgensen, W. L., Ciulli, A. & Crews, C. M. 12-Nov-2012 In : Angewandte Chemie International Edition. 51, 46, p. 11463-11467, 5 p.

    Research output: Contribution to journalArticle

  22. Chemical Proteomic Analysis Reveals the Drugability of the Kinome of Trypanosoma brucei

    Urbaniak, M. D., Mathieson, T., Bantscheff, M., Eberhard, D., Grimaldi, R., Miranda-Saavedra, D., Wyatt, P., Ferguson, M. A. J., Frearson, J. & Drewes, G. Nov-2012 In : ACS Chemical Biology. 7, 11, p. 1858-1865, 8 p.

    Research output: Contribution to journalArticle

  23. Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma

    Pohler, E. , Mamai, O. , Hirst, J. , Zamiri, M. , Horn, H. , Nomura, T. , Irvine, A. D. , Moran, B. , Wilson, N. J. , Smith, F. J. D. , Goh, C. S. M. , Sandilands, A. , Cole, C. , Barton, G. J. , Evans, A. T. , Shimizu, H. , Akiyama, M. , Suehiro, M. , Konohana, I. , Shboul, M. & 12 others Teissier, S., Boussofara, L., Denguezli, M., Saad, A., Gribaa, M., Dopping-Hepenstal, P. J., McGrath, J. A., Brown, S. J., Goudie, D. R., Reversade, B., Munro, C. S. & McLean, W. H. I. Nov-2012 In : Nature Genetics. 44, 11, p. 1272-1276, 5 p.

    Research output: Contribution to journalArticle

  24. New secreted toxins and immunity proteins encoded within the type VI secretion system gene cluster of Serratia marcescens

    English, G., Trunk, K., Rao, V. A., Srikannathasan, V., Hunter, W. N. & Coulthurst, S. J. Nov-2012 In : Molecular Microbiology. 86, 4, p. 921-936, 16 p.

    Research output: Contribution to journalArticle

  25. Dissecting fragment-based lead discovery at the von hippel-lindau protein: Hypoxia inducible factor 1α protein-protein interface

    Van Molle, I., Thomann, A., Buckley, D. L., So, E. C., Lang, S., Crews, C. M. & Ciulli, A. 26-Oct-2012 In : Chemistry & Biology. 19, 10, p. 1300-1312, 13 p.

    Research output: Contribution to journalArticle

  26. Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome

    Jones, D. C., Alphey, M. S., Wyllie, S. & Fairlamb, A. H. Oct-2012 In : Molecular Microbiology. 86, 1, p. 51-64, 14 p.

    Research output: Contribution to journalArticle

  27. Application of fragment screening and merging to the discovery of inhibitors of the Mycobacterium tuberculosis cytochrome P450 CYP121

    Hudson, S. A., McLean, K. J., Surade, S., Yang, Y-Q., Leys, D., Ciulli, A., Munro, A. W. & Abell, C. 10-Sep-2012 In : Angewandte Chemie International Edition. 51, 37, p. 9311-9316, 6 p.

    Research output: Contribution to journalArticle

  28. Transcriptome analysis of atopic skin demonstrates the importance of extracellular mechanisms in the filaggrin-related barrier defect

    Brown, S., Cole, C., McLean, I., Barton, G. & Irvine, A. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S94-S94, 1 p.

    Research output: Contribution to journalMeeting abstract

  29. Essential Role for IKK beta in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

    Pauls, E., Shpiro, N., Peggie, M., Young, E. R., Sorcek, R. J., Tan, L., Choi, H. G. & Cohen, P. 1-Jun-2012 In : Journal of Biological Chemistry. 287, 23, p. 19216-19228, 13 p.

    Research output: Contribution to journalArticle

  30. Pathways analysis in kidney cancer using proteomics approach

    Zakikhani, M., Atrih, A., Lamont, S. R., Goodman, C., Fleming, I. N. & Nabi, G. Jun-2012 In : BJU International. 109, p. 24-24, 1 p.

    Research output: Contribution to journalSpecial issue

  31. Structure and folding of a rare, natural kink turn in RNA with an A•A pair at the 2•d2n position

    Schroeder, K. T., Daldrop, P., McPhee, S. A. & Lilley, D. M. J. Jun-2012 In : RNA: a Publication of the RNA Society. 18, 6, p. 1257-1266, 10 p.

    Research output: Contribution to journalArticle

  32. Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

    Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J. 15-May-2012 In : Journal of Cell Science. 125, 10, p. 2436-2445, 10 p.

    Research output: Contribution to journalArticle

  33. Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs

    Gunn, R. N., Summerfield, S. G., Salinas, C. A., Read, K. D., Guo, Q., Searle, G. E., Parker, C. A., Jeffrey, P. & Laruelle, M. May-2012 In : Journal of Cerebral Blood Flow and Metabolism. 32, 5, p. 874-883, 10 p.

    Research output: Contribution to journalArticle

  34. Skin-targeted inhibition of PPAR β/δ by selective antagonists to treat PPAR β/δ-mediated psoriasis-like skin disease in vivo

    Hack, K., Reilly, L., Palmer, C., Read, K., Norval, S., Kime, R., Booth, K. & Foerster, J. May-2012 In : PLoS ONE. 7, 5

    Research output: Contribution to journalArticle

  35. The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases

    Izquierdo, L., Mehlert, A. & Ferguson, M. A. J. May-2012 In : Glycobiology. 22, 5, p. 696-703, 8 p.

    Research output: Contribution to journalArticle

  36. Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D. J. , Backues, S. K. , Bartholomew, C. R. , Bridges, D. , Gestwicki, J. E. , Han, T. , Jin, M. , Kim, J. K. , Lin, J. D. , Lynch-Day, M. A. , Mao, K. , Nair, U. , Parzych, K. R. , Umekawa, M. , Wang, K. , Yen, W-L. , Zhao, M. , Olsen, L. J. , Abdalla, F. C. , Marcondes, M. & 1,235 others Silva-Zacarin, E. C. M., Silva-Zacarin, E., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Chiarelli, R., Roccheri, M. C., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Saitoh, T., Al-Younes, H. M., Al-Zeer, M. A., Meyer, T. F., Albert, M. L., Albin, R. L., Dowling, J. J., Alegre-Abarrategui, J., Wade-Martins, R., Aleo, M. F., Fanzani, A., Rovetta, F., Alirezaei, M., Chisari, F. V., Whitton, J. L., Almasan, A., Almonte-Becerril, M., Kouri Flores, J. B., Amano, A., Amaravadi, R., Amarnath, S., Fowler, D. H., Amer, A. O., Drew, M. E., Andrieu-Abadie, N., Poirot, M., Vindis, C., Anantharam, V., Kanthasamy, A. G., Kanthasamy, A., Ann, D. K., Anoopkumar-Dukie, S., Grant, G. D., Aoki, H., Apostolova, N., Arancia, G., Condello, M., Meschini, S., Aris, J. P., Asanuma, K., Tomino, Y., Asare, N. Y. O., Ashida, H., Askanas, V., Nogalska, A., Askew, D. S., Auberger, P., Bost, F., Gual, P., Luciano, F., Rocchi, S., Baba, M., Baehrecke, E. H., Bahr, B. A., Bai, X-Y., Chen, X., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Brunetti-Pierri, N., Settembre, C., Bamber, B. A., Bampton, E. T. W., Melino, G., Bánhegyi, G., Bassham, D. C., Bast Jr., R. C., Fan, Z., Lopez-Berestein, G., Lu, Z., Ozpolat, B., Batoko, H., Bay, B-H., Beau, I., Esclatine, A., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Dikic, I., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Sanchez, A. M. J., Bernassola, F., Marfe, G., Palumbo, C., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Espert, L., Blum, J. S., Boise, L. H., Lonial, S., Sun, S-Y., Bonaldo, P., Sandri, M., Boone, D. L., Bornhauser, B. C., Bourquin, J-P., Bortoluci, K. R., Bossis, I., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Nezis, I. P., Rusten, T. E., Stenmark, H., Brenman, J. E., Brennand, A., Michels, P. A. M., Bresnick, E. H., Kang, Y-A., Brest, P., Hofman, P., Mograbi, B., Bristol, M. L., Gewirtz, D. A., Brookes, P. S., Johnson, G. V. W., Brown, E. J., Brumell, J. H., Huang, J., Kim, P. K., Brunk, U. T., Kurz, T., Bulman, D. E., Bultman, S. J., Bultynck, G., Parys, J. B., Burbulla, L. F., Krüger, R., Bursch, W., Butchar, J. P., Buzgariu, W., Galliot, B., Bydlowski, S. P., Cadwell, K., Cahová, M., Papackova, Z., Cai, D., Cai, J., Cai, Q., Calabretta, B., Sotgia, F., Calvo-Garrido, J., Escalante, R., Camougrand, N., Manon, S., Priault, M., Campanella, M., Campos-Salinas, J., Gonzalez-Rey, E., Oliver, F. J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Moreira, P. I., Carew, J. S., Nawrocki, S. T., Carlin, C. R., Carmignac, V., Durbeej, M., Carneiro, L. A. M., Carra, S., Kampinga, H. H., Caruso, R. A., Casari, G., Casas, C., Castino, R., Isidoro, C., Cebollero, E., Reggiori, F., Cecconi, F., Ciriolo, M. R., Piacentini, M., Celli, J., Chaachouay, H., Rodemann, H. P., Chae, H-J., Chai, C-Y., Chan, D. C., Chan, E. Y., Coombs, G. H., Chang, R. C-C., Che, C-M., Lok, C-N., Sy, L-K., Chen, C-C., Lin, W-W., Chen, G-C., Yang, W. Y., Chen, G-Q., Chen, M., Wang, J., Chen, Q., Chen, S. S-L., Ke, P-Y., Lin, Y-L., Chen, W., Chen, Y-G., Liu, Y., Yu, L., Chen, Y., Guan, J-L., Towns, R., Wiley, J. W., Chen, Y-J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Wang, H-G., Yang, J-M., El-Deiry, W. S., Cheong, H., Thompson, C. B., Cheong, J-H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H-L., Chiba, T., Chin, L-S., Li, L., Mao, Z., Chiou, S-H., Cho, C. H., Cho, D-H., Choi, A. M. K., Haspel, J. A., Henske, E. P., Nakahira, K., Ryter, S. W., Choi, D., Choi, K. S., Choi, M. E., Münger, K., Chouaib, S., Choubey, D., Choubey, V., Kaasik, A., Chu, C. T., Rabinowich, H., Chuang, T-H., Chueh, S-H., Chun, T., Park, O. K., Chwae, Y-J., Chye, M-L., Ciarcia, R., Florio, S., Granato, G. E., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Puyal, J., Clarke, R., Saha, T., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condorelli, F., Cookson, M. R., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Helfrich, M. H., Hocking, L. J., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Kaushik, S., Koga, H., Czaja, M. J., Cullen, J. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., Fueyo, J., Gomez-Manzano, C., Jiang, H., De Haan, C. A. M., Monastyrska, I., De Martino, L., Fiorito, F., Iovane, V., Pagnini, U., De Milito, A., Joseph, B., Panaretakis, T., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Schneider, C., Deng, Y. Z., Naqvi, N. I., Dengjel, J., Dent, P., Denton, D., Kumar, S., Deretic, V., Desai, S. D., Devenish, R. J., Mijaljica, D., Prescott, M., Ramm, G., Di Gioacchino, M., Di Paolo, G., Duff, K., Yu, W. H., Przedborski, S., Yamamoto, A., Di Pietro, C., Marazziti, D., Matteoni, R., Tocchini-Valentini, G., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Fotedar, R., Hansen, M., Moscat, J., Reed, J. C., Salvesen, G., Yang, Z., Diaz-Nido, J., Izquierdo, M., Dinesh-Kumar, S. P., Ding, W-X., Distelhorst, C. W., Subauste, C. S., Wang, X., Zhu, X., Oleinick, N. L., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Willbold, D., Dorsey, F. C., Dosenko, V., Doxsey, S., Dreux, M., Duan, Q., Duchosal, M. A., Dugail, I., Kroemer, G., Maiuri, M. C., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Noegel, A. A., Eissa, N. T., Lin, W-C., Ekmekcioglu, S., Elazar, Z., Elgendy, M., Minucci, S., Ellerby, L. M., Er Eng, K., McInerney, G. M., Engelbrecht, A-M., Loos, B., Engelender, S., Erenpreisa, J., Eskelinen, E-L., Espina, V., Fan, H., Fan, J., Fan, Q-W., Ilkhanizadeh, S., Weiss, W. A., Fang, S., Monteiro, M. J., Fang, Y., Fanto, M., Farkas, T., Jäättelä, M., Farré, J-C., Nazarko, T. Y., Faure, M., Fechheimer, M., Furukawa, R. H., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Gottlieb, R. A., Fisher, E. A., Fisher, P. B., Flajolet, M., Tian, Y., Florez-McClure, M. L., Fon, E. A., Fornai, F., Fortunato, F., Fox, H. S., Franco, R., Frankel, L. B., Lund, A. H., Fransen, M., Fuentes, J. M., González-Polo, R. A., Fujii, J., Fujisaki, K., Umemiya-Shirafuji, R., Fujita, E., Fukuda, M., Gaestel, M., Menon, M. B., Gailly, P., Gajewska, M., Motyl, T., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F-B., Gao, G. F., Gao, J., Garcia, L., Lavandero, S., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Golstein, P., Pierre, P., Gautel, M., Gawriluk, T. R., Hale, A. N., Ledbetter, D. J., Rucker III, E. B., Gegg, M. E., Schapira, A. H. V., Geng, J., Harper, J. W., Germain, M., Slack, R. S., Lieberman, A., Lukacs, N. W., Ghavami, S., Halayko, A. J., Kirshenbaum, L. A., Yeganeh, B., Ghosh, P., Lee, J., Giammarioli, A. M., Malorni, W., Giatromanolaki, A. N., Sivridis, E., Gibson, S. B., Gilkerson, R. W., Sulzer, D., Ginger, M. L., Ginsberg, H. N., Tabas, I., Golab, J., Goligorsky, M. S., Goncu, E., Gongora, C., Le Cam, L., Pattingre, S., Gonzalez, C. D., Vaccaro, M. I., Gonzalez, R., González-Estévez, C., Gorbunov, N. V., Gorski, S., Goruppi, S., Gozuacik, D., Green, K. N., Gregorc, A., Gros, F., Muller, S., Grose, C., Grunt, T. W., Guan, K-L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Van Den Berghe, G., Vanhorebeek, I., Gustafsson, A. B., Halonen, S. K., Hamasaki, M., Noda, T., Yoshimori, T., Han, F., Hancock, M. K., Harada, H., Harada, M., Hardt, S. E., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Hayashi, S-I., Hazelhurst, L. A., He, C., Levine, B., Terada, A. S., He, Y-W., Rathmell, J. C., Taylor, G. A., Hébert, M-J., Heidenreich, K. A., Helgason, G. V., Holyoake, T. L., Herman, B., Reiter, R. J., Herman, P. K., Hetz, C., Hilfiker, S., Navarro, M., Hill, J. A., Nemchenko, A., Yoshimoto, K., Hofmann, T. G., Höhfeld, J., Hong, M-H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C-A. 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J., Zheng, X., Zhong, Q., Zhu, C., Zhu, X-F., Zong, W-X., Zorzano, A., Zschocke, J., Zuckerbraun, B., Xie, Z. & Yamamoto, A. 1-Apr-2012 In : Autophagy. 8, 4, p. 445-544, 100 p.

    Research output: Contribution to journalArticle

  37. Human box C/D snoRNA processing conservation across multiple cell types

    Scott, M. S., Ono, M., Yamada, K., Endo, A., Barton, G. J. & Lamond, A. I. Apr-2012 In : Nucleic Acids Research. 40, 8, p. 3676-3688, 13 p.

    Research output: Contribution to journalArticle

  38. Modeling of the N-Glycosylated Transferrin Receptor Suggests How Transferrin Binding Can Occur within the Surface Coat of Trypanosoma brucei

    Mehlert, A., Wormald, M. R. & Ferguson, M. A. J. Apr-2012 In : PLoS Pathogens. 8, 4, p. -, 11 p., e1002618

    Research output: Contribution to journalArticle

  39. Regulation of the cardiac sodium pump

    Fuller, W., Tulloch, L. B., Howie, J., Wypijewski, K. J., Shattock, M. J. & Calaghan, S. C. Apr-2012 In : Cellular and Molecular Life Sciences. 70, 8, p. 1357-1380, 24 p.

    Research output: Contribution to journalArticle

  40. The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei

    Kuettel, S., Wadum, M. C. T., Guether, M. L. S., Marino, K., Riemer, C. & Ferguson, M. A. J. Apr-2012 In : Molecular Microbiology. 84, 2, p. 340-351, 12 p.

    Research output: Contribution to journalArticle

  41. Transcriptome analysis of skin reveals differences between atopic eczema cases stratified for filaggrin genotype

    Brown, S., Cole, C., Irvine, A., Barton, G. & McLean, I. Apr-2012 In : British Journal of Dermatology. 166, 4, p. e26-e27, 2 p., O-30

    Research output: Contribution to journalArticle

  42. Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction

    Buckley, D. L., Van Molle, I., Gareiss, P. C., Tae, H. S., Michel, J., Noblin, D. J., Jorgensen, W. L., Ciulli, A. & Crews, C. M. 14-Mar-2012 In : Journal of the American Chemical Society. 134, 10, p. 4465-4468, 4 p.

    Research output: Contribution to journalArticle

  43. A quantitative spatial proteomics analysis of proteome turnover in human cells

    Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I. 1-Mar-2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  44. Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

    Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M. D. Mar-2012 In : Chemical Biology & Drug Design. 79, 3, p. 270-278, 9 p.

    Research output: Contribution to journalArticle

  45. Conserved signal peptide recognition systems across the prokaryotic domains

    Coulthurst, S. J., Dawson, A., Hunter, W. N. & Sargent, F. 28-Feb-2012 In : Biochemistry. 51, 8, p. 1678-1686, 9 p.

    Research output: Contribution to journalArticle

  46. Synergy of peptide and sugar in O-GlcNAcase substrate recognition

    Schimpl, M., Borodkin, V. S., Gray, L. J. & van Aalten, D. M. F. 24-Feb-2012 In : Chemistry & Biology. 19, 2, p. 173-178, 6 p.

    Research output: Contribution to journalArticle

  47. Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism

    Daneshvar, H., Wyllie, S., Phillips, S., Hagan, P. & Burchmore, R. 16-Feb-2012 In : Journal of Proteomics. 75, 5, p. 1463-1471, 9 p.

    Research output: Contribution to journalArticle

  48. Identification and localisation of the NB-LRR gene family within the potato genome

    Jupe, F., Pritchard, L., Etherington, G. J., MacKenzie, K., Cock, P. J. A., Wright, F., Sharma, S. K., Bolser, D., Bryan, G. J., Jones, J. D. G. & Hein, I. 15-Feb-2012 In : BMC Genomics. 13, p. -, 14 p., 75

    Research output: Contribution to journalArticle

  49. Quinol derivatives as potential trypanocidal agents

    Capes, A., Patterson, S., Wyllie, S., Hallyburton, I., Collie, I. T., McCarroll, A. J., Stevens, M. F. G., Frearson, J. A., Wyatt, P. G., Fairlamb, A. H. & Gilbert, I. H. 15-Feb-2012 In : Bioorganic & Medicinal Chemistry. 20, 4, p. 1607-1615, 9 p.

    Research output: Contribution to journalArticle

  50. Infectious disease: Genomics decodes drug action

    Fairlamb, A. H. 9-Feb-2012 In : Nature. 482, 7384, p. 167-169, 3 p.

    Research output: Contribution to journalEditorial

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