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  1. Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

    Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D. Apr 2014 In : The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

    Research output: Contribution to journalArticle

  2. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  3. Clinical trial design for older people - time for a rethink

    Witham, M. D. & George, J. 2014 In : QJM : an International Journal of Medicine. 107, 1, p. 15-16 2 p.

    Research output: Contribution to journalArticle

  4. Common variants in Mendelian kidney disease genes and their association with renal function

    Parsa, A. , Fuchsberger, C. , Köttgen, A. , O'Seaghdha, C. M. , Pattaro, C. , de Andrade, M. , Chasman, D. I. , Teumer, A. , Endlich, K. , Olden, M. , Chen, M-H. , Tin, A. , Kim, Y. J. , Taliun, D. , Li, M. , Feitosa, M. , Gorski, M. , Yang, Q. , Hundertmark, C. , Foster, M. C. & 139 others Glazer, N., Isaacs, A., Rao, M., Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Tönjes, A., Dehghan, A., Couraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimäki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Hofer, E., Hu, F., Demirkan, A., Oostra, B. A., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Giulianini, F., Koenig, W., Illig, T., Döring, A., Wichmann, H-E., Zgaga, L., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nöthlings, U., Jacobs, G., Biffar, R., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Völker, U., Völzke, H., Kovacs, P., Stumvoll, M., Mägi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Stengel, B., Ruggiero, D., Bergmann, S., Kähönen, M., Viikari, J., Nikopensius, T., Province, M., Colhoun, H., Doney, A., Robino, A., Krämer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G-A., Paulweber, B., Haun, M., Sala, C., Mitchell, P., Ciullo, M., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J., Hayward, C., Ridker, P. M., Bochud, M., Heid, I. M., Siscovick, D. S., Fox, C. S., Kao, W. L. & Böger, C. A. Dec 2013 In : Journal of the American Society of Nephrology. 24, 12, p. 2105-2117 13 p.

    Research output: Contribution to journalArticle

  5. Glycemic exposure and blood pressure influencing progression and remission of diabetic retinopathy: a longitudinal cohort study in GoDARTS

    Liu, Y., Wang, M., Morris, A. D., Doney, A. S. F., Leese, G. P., Pearson, E. R. & Palmer, C. N. A. Dec 2013 In : Diabetes Care. 36, 12, p. 3979-3984 6 p.

    Research output: Contribution to journalArticle

  6. Overcoming obstacles to clinical research in older people

    Goodbrand, J. A. & McMurdo, M. E. T. Dec 2013 In : Maturitas. 76, 4, p. 294-295 2 p.

    Research output: Contribution to journalEditorial

  7. State of play of pharmacogenetics and personalized medicine in heart failure

    Parry, H. M., Doney, A., Palmer, C. N. & Lang, C. C. Dec 2013 In : Cardiovascular Therapeutics. 31, 6, p. 315-322 8 p.

    Research output: Contribution to journalArticle

  8. Guillain-Barre syndrome-like illness in association with electrical shock injury

    Anderson, M. L. & O'Riordan, J. 17 Oct 2013 In : BMJ Case Reports. 201532

    Research output: Contribution to journalArticle

  9. Surgical interventions for the early management of Bell's palsy

    McAllister, K., Walker, D., Donnan, P. T. & Swan, I. 16 Oct 2013 In : Cochrane Database of Systematic Reviews. 10, 20 p.CD007468

    Research output: Contribution to journalArticle

  10. Medical management of critical limb ischaemia: where do we stand today?

    Lambert, M. A. & Belch, J. J. F. Oct 2013 In : Journal of Internal Medicine. 274, 4, p. 295-307 13 p.

    Research output: Contribution to journalArticle

  11. CFTR: a hub for kinases and cross-talk of cAMP and Ca(2+)

    Kunzelmann, K. & Mehta, A. Sep 2013 In : FEBS Journal. 280, 18, p. 4417-4429 13 p.

    Research output: Contribution to journalArticle

  12. Integrating palliative care in lung cancer: an early feasibility study

    Johnston, B., Buchanan, D., Papadopoulou, C., Sandeman, G. & Lord, H. Sep 2013 In : International Journal of Palliative Nursing. 19, 9, p. 433-437 5 p.

    Research output: Contribution to journalArticle

  13. Direct comparisons of three alternative plasma fibrinogen assays with the Von Clauss assay in prediction of cardiovascular disease and all-causes mortality: the Scottish heart health extended cohort

    Peters, S. A. E., Woodward, M., Rumley, A., Koenig, W., Tunstall-Pedoe, H. & Lowe, G. D. O. Aug 2013 In : British Journal of Haematology. 162, 3, p. 392-399 8 p.

    Research output: Contribution to journalArticle

  14. Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis

    Parry, H. M., Donnelly, L. A., Van Zuydam, N., Doney, A. S. F., Elder, D. H. J., Morris, A. D., Struthers, A. D., Palmer, C. N. A., Lang, C. C. & Wellcome Trust Case Control Consortium 2 23 Jul 2013 In : Cardiovascular Diabetology. 12, 109

    Research output: Contribution to journalArticle

  15. Neurological improvement following reinstitution of a low phenylalanine diet after 20 years in established pnenylketonuria

    Anwar, M. S., Waddell, B. & O'Riordan, J. 12 Jul 2013 In : BMJ Case Reports. 010509

    Research output: Contribution to journalArticle

  16. Acute motor neuropathy with pure distal involvement - a case report of multifocal motor neuropathy

    Ramdas, S., Prasad, M., Spillane, K. & Kirkpatrick, M. Jul 2013 In : European Journal of Paediatric Neurology. 17, 4, p. 415-418 4 p.

    Research output: Contribution to journalArticle

  17. Estimated GFR reporting is associated with decreased nonsteroidal anti-inflammatory drug prescribing and increased renal function

    Wei, L., MacDonald, T. M., Jennings, C., Sheng, X., Flynn, R. W. & Murphy, M. J. Jul 2013 In : Kidney International. 84, 1, p. 174-178 5 p.

    Research output: Contribution to journalArticle

  18. Clinical research must include more older people

    McMurdo, M. 21 Jun 2013 In : BMJ. 346, 2 p.f3899

    Research output: Contribution to journalComment/debate

  19. Randomised Placebo-controlled Trial to Evaluate Chronic Dosing Effects of Propranolol in Asthma

    Short, P. M., Williamson, P. A., Anderson, W. J. & Lipworth, B. J. 15 Jun 2013 In : American Journal of Respiratory and Critical Care Medicine. 187, 12, p. 1308-1314 7 p.

    Research output: Contribution to journalArticle

  20. Genetic Loci for retinal arteriolar microcirculation

    Sim, X. , Jensen, R. A. , Ikram, M. K. , Cotch, M. F. , Li, X. , MacGregor, S. , Xie, J. , Smith, A. V. , Boerwinkle, E. , Mitchell, P. , Klein, R. , Klein, B. E. K. , Glazer, N. L. , Lumley, T. , McKnight, B. , Psaty, B. M. , de Jong, P. T. V. M. , Hofman, A. , Rivadeneira, F. , Uitterlinden, A. G. & 38 others van Duijn, C. M., Aspelund, T., Eiriksdottir, G., Harris, T. B., Jonasson, F., Launer, L. J., Wellcome Trust Case Control Consortium 2, Attia, J., Baird, P. N., Harrap, S., Holliday, E. G., Inouye, M., Rochtchina, E., Scott, R. J., Viswanathan, A., Global BPGen Consortium, Li, G., Smith, N. L., Wiggins, K. L., Kuo, J. Z., Taylor, K. D., Hewitt, A. W., Martin, N. G., Montgomery, G. W., Sun, C., Young, T. L., Mackey, D. A., van Zuydam, N. R., Doney, A. S. F., Palmer, C. N. A., Morris, A. D., Rotter, J. I., Tai, E. S., Gudnason, V., Vingerling, J. R., Siscovick, D. S., Wang, J. J. & Wong, T. Y. Jun 2013 In : PLoS ONE. 8, 6, e65804

    Research output: Contribution to journalArticle

  21. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 10 May 2013 In : Journal of Biological Chemistry. 288, 19, p. 13808-13820 13 p.

    Research output: Contribution to journalArticle

  22. Real-time RT-PCR threshold cycles value for Kir6.1 from the blood correlates with parameters of vascular function: a potential for the vascular function biomarker?

    Khan, F., Choong, W. L., Du, Q. & Jovanovic, A. May 2013 In : Biomarkers. 18, 3, p. 221-229 9 p.

    Research output: Contribution to journalArticle

  23. Does the anticholinergic risk score predict death in older people after discharge from inpatient rehabilitation?

    Walesby, K. E., Sumukadas, D., Ramage, L., McMurdo, M. E., Mangoni, A. A. & Witham, M. D. Apr 2013 In : Journal of the American Geriatrics Society. 61, Suppl. 1, p. S142 1 p.C45

    Research output: Contribution to journalMeeting abstract

  24. Tailored second-line therapy in asthmatic children with the Arg16 genotype

    Lipworth, B. J., Basu, K., Donald, H. P., Tavendale, R., MacGregor, D. F., Ogston, S. A., Palmer, C. N. A. & Mukhopadhyay, S. Apr 2013 In : Clinical Science. 124, 8, p. 521-528 8 p.

    Research output: Contribution to journalArticle

  25. Targeting the small airways asthma phenotype: if we can reach it, should we treat it?

    Lipworth, B. Apr 2013 In : Annals of Allergy, Asthma & Immunology. 110, 4, p. 233-239 7 p.

    Research output: Contribution to journalArticle

  26. Adrenal suppression with fluticasone furoate

    Lipworth, B. J. Mar 2013 In : Annals of Allergy, Asthma & Immunology. 110, 3, p. 213

    Research output: Contribution to journalLetter

  27. Clinical predictors of rate of progression of type 2 diabetes: an extreme case-control study

    Donnelly, L. A., Zhou, K., Palmer, C. N. A., Doney, A. S. F., Morris, A. D. & Pearson, E. R. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 94-94 1 p.P213

    Research output: Contribution to journalMeeting abstract

  28. Getting to the heart of inpatient diabetes care

    Jordan, L. V. M., Voigt, D. J. & Brennan, G. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 151-151 1 p.P410

    Research output: Contribution to journalMeeting abstract

  29. Influence of β2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients

    Manoharan, A., Anderson, W. J. & Lipworth, B. J. Mar 2013 In : Annals of Allergy, Asthma & Immunology. 110, 3, p. 161-164 4 p.

    Research output: Contribution to journalArticle

  30. Is thiazolidinedione treatment an important cause of oedema?

    Vella, S., Donnelly, L., Lang, C. C., Pearson, E. R. & Petrie, J. R. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 197-197 1 p.P562

    Research output: Contribution to journalMeeting abstract

  31. Measuring endogenous insulin secretion in type 1 diabetes is life changing

    Connelly, P. J., Gellatly, E., Bell, L., Shepherd, M., Hattersley, A. T. & Pearson, E. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 94-95 2 p.P215

    Research output: Contribution to journalMeeting abstract

  32. Should I eXtract Every Six dental trial (SIXES): study protocol for a randomized controlled trial

    Innes, N., Borrie, F., Bearn, D., Evans, D., Rauchhaus, P., McSwiggan, S., Page, L. F. & Hogarth, F. 27 Feb 2013 In : Trials. 14, 59

    Research output: Contribution to journalArticle

  33. Temporary brittle bone disease: association with intracranial bleeding

    Monk, E. & Paterson, C. R. 15 Feb 2013 In : Journal of Pediatric Endocrinology & Metabolism. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  34. Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B

    Ballantyne, T., Du, Q., Jovanovic, S., Neemo, A., Holmes, R., Sinha, S. & Jovanovic, A. Feb 2013 In : International Journal of Biochemistry & Cell Biology. 45, 2, p. 283-291 9 p.

    Research output: Contribution to journalArticle

  35. Aortic valvular heart disease: is there a place for angiotensin-converting-enzyme inhibitors?

    Elder, D. H. J., McAlpine-Scott, V., Choy, A. M., Struthers, A. D. & Lang, C. C. Jan 2013 In : Expert Review of Cardiovascular Therapy. 11, 1, p. 107-14 8 p.

    Research output: Contribution to journalArticle

  36. Inhaled and Systemic Corticosteroid Response in Severe Asthma Assessed by Alveolar Nitric Oxide: a randomised crossover pilot study of add-on therapy

    Williamson, P. A., Short, P. M., Vaidyanathan, S. & Lipworth, B. J. Jan 2013 In : British Journal of Clinical Pharmacology. 75, 1, p. 93-102 10 p.

    Research output: Contribution to journalArticle

  37. Large-scale association analysis identifies new risk loci for coronary artery disease

    Deloukas, P. , Kanoni, S. , Willenborg, C. , Farrall, M. , Assimes, T. L. , Thompson, J. R. , Ingelsson, E. , Saleheen, D. , Erdmann, J. , Goldstein, B. A. , Stirrups, K. , König, I. R. , Cazier, J-B. , Johansson, A. , Hall, A. S. , Lee, J-Y. , Willer, C. J. , Chambers, J. C. , Esko, T. , Folkersen, L. & 164 others Goel, A., Grundberg, E., Havulinna, A. S., Ho, W. K., Hopewell, J. C., Eriksson, N., Kleber, M. E., Kristiansson, K., Lundmark, P., Lyytikäinen, L-P., Rafelt, S., Shungin, D., Strawbridge, R. J., Thorleifsson, G., Tikkanen, E., Van Zuydam, N., Voight, B. F., Waite, L. L., Zhang, W., Ziegler, A., Absher, D., Altshuler, D., Balmforth, A. J., Barroso, I., Braund, P. S., Burgdorf, C., Claudi-Boehm, S., Cox, D., Dimitriou, M., Do, R., Doney, A. S. F., El Mokhtari, N., Eriksson, P., Fischer, K., Fontanillas, P., Franco-Cereceda, A., Gigante, B., Groop, L., Gustafsson, S., Hager, J., Hallmans, G., Han, B-G., Hunt, S. E., Kang, H. M., Illig, T., Kessler, T., Knowles, J. W., Kolovou, G., Kuusisto, J., Langenberg, C., Langford, C., Leander, K., Lokki, M-L., Lundmark, A., McCarthy, M. I., Meisinger, C., Melander, O., Mihailov, E., Maouche, S., Morris, A. D., Müller-Nurasyid, M., Nikus, K., Peden, J. F., Rayner, N. W., Rasheed, A., Rosinger, S., Rubin, D., Rumpf, M. P., Schäfer, A., Sivananthan, M., Song, C., Stewart, A. F. R., Tan, S-T., Thorgeirsson, G., van der Schoot, C. E., Wagner, P. J., Wells, G. A., Wild, P. S., Yang, T-P., Amouyel, P., Arveiler, D., Basart, H., Boehnke, M., Boerwinkle, E., Brambilla, P., Cambien, F., Cupples, A. L., de Faire, U., Dehghan, A., Diemert, P., Epstein, S. E., Evans, A., Ferrario, M. M., Ferrières, J., Gauguier, D., Go, A. S., Goodall, A. H., Gudnason, V., Hazen, S. L., Holm, H., Iribarren, C., Jang, Y., Kähönen, M., Kee, F., Kim, H-S., Klopp, N., Koenig, W., Kratzer, W., Kuulasmaa, K., Laakso, M., Laaksonen, R., Lee, J-Y., Lind, L., Ouwehand, W. H., Parish, S., Park, J. E., Pedersen, N. L., Peters, A., Quertermous, T., Rader, D. J., Salomaa, V., Schadt, E., Shah, S. H., Sinisalo, J., Stark, K., Stefansson, K., Trégouët, D-A., Virtamo, J., Wallentin, L., Wareham, N., Zimmermann, M. E., Nieminen, M. S., Hengstenberg, C., Sandhu, M. S., Pastinen, T., Syvänen, A-C., Hovingh, G. K., Dedoussis, G., Franks, P. W., Lehtimäki, T., Metspalu, A., Zalloua, P. A., Siegbahn, A., Schreiber, S., Ripatti, S., Blankenberg, S. S., Perola, M., Clarke, R., Boehm, B. O., O'Donnell, C., Reilly, M. P., März, W., Collins, R., Kathiresan, S., Hamsten, A., Kooner, J. S., Thorsteinsdottir, U., Danesh, J., Palmer, C. N. A., Roberts, R., Watkins, H., Schunkert, H., Samani, N. J. & CARDIoGRAMplusC4D Consortium Jan 2013 In : Nature Genetics. 45, 1, p. 25-33 9 p.

    Research output: Contribution to journalArticle

  38. Left Ventricular Hypertrophy in COPD Without Hypoxemia: The Elephant in the Room?

    Anderson, W. J., Lipworth, B. J., Rekhraj, S., Struthers, A. D. & George, J. Jan 2013 In : CHEST. 143, 1, p. 91-97 7 p.

    Research output: Contribution to journalArticle

  39. Pioglitazone and bladder cancer: A propensity score matched cohort study

    Wei, L., Macdonald, T. M. & Mackenzie, I. S. Jan 2013 In : British Journal of Clinical Pharmacology. 75, 1, p. 254-259 6 p.

    Research output: Contribution to journalArticle

  40. A new approach to residual risk in treated hypertension--3P screening

    Struthers, A. D. 2013 In : Hypertension. 62, 2, p. 236-239 4 p.

    Research output: Contribution to journalArticle

  41. A nonsense mutation in the mattrin gene causes the matted mouse phenotype and is a predisposing gene for atopic dermatitis in humans

    Goh, C. S., Saunders, S. P., Cole, C., Weidinger, S., Baurecht, H., Lee, Y., Reynolds, N. J., Barker, J. N., Cordell, H. J., Brown, S. J., Irvine, A. D., McLean, I., Sandilands, A. & Fallon, P. G. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S145 1 p.854

    Research output: Contribution to journalMeeting abstract

  42. Adverse psychological effects and costs associated with waiting for radiofrequency ablation

    Barclay, J. L., Gibson, P. H., Lewis, A., Wilson, C., Affolter, J. T., Patel, J. C., Scott, N. W., Alexander, D. A., Choy, A. M. & Broadhurst, P. A. 2013 In : Pacing and Clinical Electrophysiology. 36, 6, p. 719-726 8 p.

    Research output: Contribution to journalArticle

  43. Allopurinol reduces left ventricular mass in patients with type ii diabetes and left ventricular hypertrophy

    Szwejkowski, B. R., Gandy, S., Rekhraj, S., Houston, G., George, J., Lang, C. C., Morris, A. D. & Struthers, A. D. 2013 In : Journal of the American College of Cardiology. 61, 10 Supplement, p. E1256 1 p.

    Research output: Contribution to journalMeeting abstract

  44. Allopurinol use is associated with greater functional gains in older rehabilitation patients

    Beveridge, L. A., Ramage, L., McMurdo, M. E. T., George, J. & Witham, M. D. 2013 In : Age and Ageing. 42, 3, p. 400-404 5 p.

    Research output: Contribution to journalArticle

  45. ANO5 gene analysis in a large cohort of patients with anoctaminopathy: confirmation of male prevalence and high occurrence of the common exon 5 gene mutation

    Sarkozy, A. , Hicks, D. , Hudson, J. , Laval, S. H. , Barresi, R. , Hilton-Jones, D. , Deschauer, M. , Harris, E. , Rufibach, L. , Hwang, E. , Bashir, R. , Walter, M. C. , Krause, S. , van den Bergh, P. , Illa, I. , Penisson-Besnier, I. , De Waele, L. , Turnbull, D. , Guglieri, M. , Schrank, B. & 43 others Schoser, B., Seeger, J., Schreiber, H., Glaeser, D., Eagle, M., Bailey, G., Walters, R., Longman, C., Norwood, F., Winer, J., Muntoni, F., Hanna, M., Roberts, M., Bindoff, L. A., Brierley, C., Cooper, R. G., Cottrell, D. A., Davies, N. P., Gibson, A., Gorman, G. S., Hammans, S., Jackson, A. P., Khan, A., Lane, R., McConville, J., McEntagart, M., Al-Memar, A., Nixon, J., Panicker, J., Parton, M., Petty, R., Price, C. J., Rakowicz, W., Ray, P., Schapira, A. H., Swingler, R., Turner, C., Wagner, K. R., Maddison, P., Shaw, P. J., Straub, V., Bushby, K. & Lochmuller, H. 2013 In : Human Mutation. 34, 8, p. 1111-1118 8 p.

    Research output: Contribution to journalArticle

  46. Birt-hogg-dube syndrome is a novel ciliopathy

    Luijten, M., Claessens, T., Basten, S., Vernooij, M., Menko, F., Nookala, R., Scott, C., van Geel, M., Janssen, R., Easton, J., Vreeburg, M., Kamps, M., Land, S., Tee, A., Giles, R., Coull, B. & van Steensel, M. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S136 1 p.800

    Research output: Contribution to journalMeeting abstract

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