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  1. AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

    Hardie, D. G. Apr 2015 In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  2. Carnosic acid stimulates glucose uptake in skeletal muscle cells via a PME-1/PP2A/PKB signalling axis

    Lipina, C. & Hundal, H. S. Nov 2014 In : Cellular Signalling. 26, 11, p. 2343-2349 6 p.

    Research output: Contribution to journalArticle

  3. Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

    Bago, R., Malik, N., Munson, M. J., Prescott, A. R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I. G. & Alessi, D. R. Nov 2014 In : Biochemical Journal. 463, 3, p. 413-427 15 p.

    Research output: Contribution to journalArticle

  4. Valuation of hospital bed-days released by infection control programs: a comparison of methods

    Stewardson, A. J., Harbarth, S., Graves, N. & TIMBER Study Group Oct 2014 In : Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America. 35, 10, p. 1294-1297 4 p.

    Research output: Contribution to journalArticle

  5. Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

    Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A. 2 Sep 2014 In : PLoS ONE. 9, 9, 7 p.e106710

    Research output: Contribution to journalArticle

  6. Cystatin F regulates proteinase activity in IL-2-activated natural killer cells

    Maher, K., Konjar, S., Watts, C., Turk, B. & Kopitar-Jerala, N. 1 Sep 2014 In : Protein and Peptide Letters. 21, 9, p. 957-965 9 p.

    Research output: Contribution to journalArticle

  7. Peripheral prion disease pathogenesis is unaltered in the absence of sialoadhesin (Siglec-1/CD169)

    Bradford, B. M., Crocker, P. R. & Mabbott, N. A. 1 Sep 2014 In : Immunology. 143, 1, p. 120-129 10 p.

    Research output: Contribution to journalArticle

  8. Introduction to special issue: 'emerging roles of siglecs in health and disease'

    Crocker, P. R. & Kannagi, R. Sep 2014 In : Glycobiology. 24, 9, p. 784-784 1 p.

    Research output: Contribution to journalArticle

  9. Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

    Chang, Y-C., Olson, J., Louie, A., Crocker, P. R., Varki, A. & Nizet, V. Sep 2014 In : Journal of Molecular Medicine. 92, 9, p. 951-959 9 p.

    Research output: Contribution to journalArticle

  10. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  11. Mitochondria: a possible nexus for the regulation of energy homeostasis by the endocannabinoid system?

    Lipina, C., Irving, A. J. & Hundal, H. S. 1 Jul 2014 In : American Journal of Physiology, Endocrinology and Metabolism. 307, 1, p. E1-E13

    Research output: Contribution to journalArticle

  12. PDK1 controls upstream PI3K expression and PIP3 generation

    Dieterle, A. M., Böhler, P., Keppeler, H., Alers, S., Berleth, N., Drießen, S., Hieke, N., Pietkiewicz, S., Löffler, A. S., Peter, C., Gray, A., Leslie, N. R., Shinohara, H., Kurosaki, T., Engelke, M., Wienands, J., Bonin, M., Wesselborg, S. & Stork, B. 5 Jun 2014 In : Oncogene. 33, 23, p. 3043-3053 11 p.

    Research output: Contribution to journalArticle

  13. Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies

    Pearce, O. M. T., Läubli, H., Verhagen, A., Secrest, P., Zhang, J., Varki, N. M., Crocker, P. R., Bui, J. D. & Varki, A. 22 Apr 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 16, p. 5998-6003 6 p.

    Research output: Contribution to journalArticle

  14. Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

    Hawley, S. A., Ross, F. A., Gowans, G. J., Tibarewal, P., Leslie, N. R. & Hardie, D. G. 15 Apr 2014 In : Biochemical Journal. 459, 2, p. 275-287 13 p.

    Research output: Contribution to journalArticle

  15. A new protein kinase cascade

    Hardie, D. G. Apr 2014 In : Nature Reviews Molecular Cell Biology. 15, 4, p. 223 1 p.

    Research output: Contribution to journalArticle

  16. Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors

    Liu, R., Iadevaia, V., Averous, J., Taylor, P. M., Zhang, Z. & Proud, C. G. Apr 2014 In : Nucleic Acids Research. 42, 8, p. 5083-5096 14 p.

    Research output: Contribution to journalArticle

  17. A H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation

    Sabbattini, P., Sjoberg, M., Nikic, S., Frangini, A., Holmqvist, P-H., Kunowska, N., Carroll, T., Brookes, E., Arthur, S. J., Pombo, A. & Dillon, N. 15 Mar 2014 In : Molecular Biology of the Cell. 25, 6, p. 904-915 12 p.

    Research output: Contribution to journalArticle

  18. AMPK: regulating energy balance at the cellular and whole body levels

    Hardie, D. G. & Ashford, M. L. J. Mar 2014 In : Physiology. 29, 2, p. 99-107 9 p.

    Research output: Contribution to journalArticle

  19. Enhanced insulin sensitivity associated with provision of mono and polyunsaturated fatty acids in skeletal muscle cells involves counter modulation of PP2A

    Nardi, F., Lipina, C., Magill, D., Hage Hassan, R., Hajduch, E., Gray, A. & Hundal, H. S. Mar 2014 In : PLoS ONE. 9, 3, 10 p.e92255

    Research output: Contribution to journalArticle

  20. Transcriptionally correlated subcellular dynamics of MBNL1 during lens development and their implication for the molecular pathology of myotonic dystrophy type 1

    Coleman, S. M., Prescott, A. R. & Sleeman, J. E. Mar 2014 In : Biochemical Journal. 458, 2, p. 267-280 14 p.

    Research output: Contribution to journalArticle

  21. Time-resolved quantitative proteomics implicates the core snRNP protein SmB together with SMN in neural trafficking

    Prescott, A. R., Bales, A., James, J., Trinkle-Mulcahy, L. & Sleeman, J. E. 15 Feb 2014 In : Journal of Cell Science. 127, 4, p. 812-827 16 p.

    Research output: Contribution to journalArticle

  22. AMPK: a cellular energy sensor primarily regulated by AMP

    Gowans, G. J. & Hardie, D. G. 1 Feb 2014 In : Biochemical Society Transactions. 42, 1, p. 71-75 5 p.

    Research output: Contribution to journalArticle

  23. RAM function is dependent on Kapβ2-mediated nuclear entry

    Gonatopoulos-Pournatzis, T. & Cowling, V. H. 1 Feb 2014 In : Biochemical Journal. 457, 3, p. 473-484 12 p.

    Research output: Contribution to journalArticle

  24. Cap-binding complex (CBC)

    Gonatopoulos-Pournatzis, T. & Cowling, V. H. 15 Jan 2014 In : Biochemical Journal. 457, 2, p. 231-242 12 p.

    Research output: Contribution to journalScientific review

  25. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

    Banerjee, S., Buhrlage, S. J., Huang, H-T., Deng, X., Zhou, W., Wang, J., Traynor, R., Prescott, A. R., Alessi, D. R. & Gray, N. S. 1 Jan 2014 In : Biochemical Journal. 457, 1, p. 215-225 11 p.

    Research output: Contribution to journalArticle

  26. Role of amino acid transporters in amino acid sensing

    Taylor, P. M. Jan 2014 In : American Journal of Clinical Nutrition. 99, 1, p. 2235-2305 71 p.

    Research output: Contribution to journalArticle

  27. A critical role for beta2 integrins in podosome formation, dynamics and TLR-signaled disassembly in dendritic cells

    Gawden-Bone, C., West, M. A., Morrison, V. L., Edgar, A. J., McMillan, S. J., Dill, B. D., Trost, M., Prescott, A., Fagerholm, S. C. & Watts, C. 2014 In : Journal of Cell Science. 37 p.

    Research output: Contribution to journalArticle

  28. AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

    Hardie, D. G. 2014 In : Journal of Internal Medicine. 17 p.

    Research output: Contribution to journalArticle

  29. Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK-TssFG sub-complex

    English, G., Byron, O., Cianfanelli, F. R., Prescott, A. R. & Coulthurst, S. J. 2014 In : Biochemical Journal. 461, 2, p. 291-304 14 p.

    Research output: Contribution to journalArticle

  30. Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight

    Mahfouz, R., Khoury, R., Blachnio-Zabielska, A., Turban, S., Loiseau, N., Lipina, C., Stretton, C., Bourron, O., Ferré, P., Foufelle, F., Hundal, H. S. & Hajduch, E. 2014 In : PLoS ONE. 9, 7, 9 p.e101865

    Research output: Contribution to journalArticle

  31. High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics

    Güther, M. L. S., Urbaniak, M., Tavendale, A., Prescott, A. & Ferguson, M. A. J. 2014 In : Journal of Proteome Research. 13, 6, p. 2796-2806 11 p.

    Research output: Contribution to journalArticle

  32. Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase

    Banerjee, S., Zagorska, A., Deak, M., Campbell, D. G., Prescott, A. R. & Alessi, D. R. 2014 In : Biochemical Journal. 461, 2, p. 233-245 13 p.

    Research output: Contribution to journalArticle

  33. Leucoerythroblastic anaemia, abnormal bone scan and prostate cancer with a primary haematological diagnosis

    Preston, G., Meiklejohn, D. & Thomas, N. 2014 In : British Journal of Haematology. 1 p.

    Research output: Contribution to journalArticle

  34. Mechanism of Action of Compound-13: an α1-Selective Small Molecule Activator of AMPK

    Hunter, R. W., Foretz, M., Bultot, L., Fullerton, M. D., Deak, M., Ross, F. A., Hawley, S. A., Shpiro, N., Viollet, B., Barron, D., Kemp, B. E., Steinberg, G. R., Hardie, D. G. & Sakamoto, K. 2014 In : Chemistry & Biology. 21, 7, p. 866-879 14 p.

    Research output: Contribution to journalArticle

  35. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

    Pirkmajer, S., Kulkarni, S. S., Tom, R. Z., Ross, F. A., Hawley, S. A., Hardie, D. G., Zierath, J. R. & Chibalin, A. V. 2014 In : Diabetes. 10 p.

    Research output: Contribution to journalArticle

  36. Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model

    McMillan, S. J., Richards, H. E. & Crocker, P. R. 2014 In : Immunology Letters. 160, 1, p. 11-16 6 p.

    Research output: Contribution to journalArticle

  37. Siglec-mediated regulation of immune cell function in disease

    Macauley, M. S., Crocker, P. R. & Paulson, J. C. 2014 In : Nature Reviews Immunology. 14, 10, p. 653-666 14 p.

    Research output: Contribution to journalArticle

  38. Structural and functional basis for p38-MK2 activated Rsk signalling in TLR stimulated dendritic cells

    Zaru, R., Edgar, A. J., Hanauer, A. & Watts, C. 2014 In : Molecular and Cellular Biology. 30 p.

    Research output: Contribution to journalArticle

  39. Transcriptional regulation of IL-10 and its cell-specific role in vivo

    MacKenzie, K. F., Pattison, M. J. & Arthur, J. S. C. 2014 In : Critical Reviews in Immunology. 34, 4, p. 315-345 31 p.

    Research output: Contribution to journalArticle

  40. Characterization of Native Protein Complexes and Protein Isoform Variation Using Size-fractionation-based Quantitative Proteomics

    Kirkwood, K. J., Ahmad, Y., Larance, M. & Lamond, A. I. 1 Dec 2013 In : Molecular & Cellular Proteomics. 12, 12, p. 3851-3873 23 p.

    Research output: Contribution to journalArticle

  41. Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis

    von Wilamowitz-Moellendorff, A., Hunter, R. W., García-Rocha, M., Kang, L., López-Soldado, I., Lantier, L., Patel, K., Peggie, M. W., Martínez-Pons, C., Voss, M., Calbó, J., Cohen, P. T. W., Wasserman, D. H., Guinovart, J. J. & Sakamoto, K. Dec 2013 In : Diabetes. 62, 12, p. 4070-4082 13 p.

    Research output: Contribution to journalArticle

  42. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

    Brown, S. J. , Madhok, V. B. & 32 others Saunders, S. P., Goh, C. S. M., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G. Nov 2013 In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

    Research output: Contribution to journalArticle

  43. A synthetic system for expression of components of a bacterial microcompartment

    Sargent, F., Davidson, F. A., Kelly, C. L., Binny, R., Christodoulides, N., Gibson, D., Johansson, E., Kozyrska, K., Licandro Lado, L., MacCallum, J., Montague, R., Ortmann, B., Owen, R., Coulthurst, S. J., Dupuy, L., Prescott, A. R. & Palmer, T. Nov 2013 In : Microbiology-SGM. 159, 11, p. 2427-2436 10 p.

    Research output: Contribution to journalArticle

  44. The interferon response to intracellular DNA: Why so many receptors?

    Unterholzner, L. Nov 2013 In : Immunobiology. 218, 11, p. 1312-1321 10 p.

    Research output: Contribution to journalArticle

  45. Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases

    Castor, D., Nair, N., Déclais, A-C., Lachaud, C., Toth, R., Macartney, T. J., Lilley, D. M. J., Arthur, J. S. C. & Rouse, J. 24 Oct 2013 In : Molecular Cell. 52, 2, p. 221-233 13 p.

    Research output: Contribution to journalArticle

  46. AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

    Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G. 1 Oct 2013 In : Cell Metabolism. 18, 4, p. 556-566 11 p.

    Research output: Contribution to journalArticle

  47. Mitochondrial Substrate Availability and its Role in Lipid-Induced Insulin Resistance and Proinflammatory Signalling in Skeletal Muscle

    Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowksi, M., Gorski, J., Burgess, K. & Hundal, H. S. Oct 2013 In : Diabetes. 62, 10, p. 3426-3436 11 p.

    Research output: Contribution to journalArticle

  48. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

    Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P. 17 Sep 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.

    Research output: Contribution to journalArticle

  49. Localization-dependent and -independent roles of SLX4 in regulating telomeres

    Wilson, J. S. J., Tejera, A. M., Castor, D., Toth, R., Blasco, M. A. & Rouse, J. 12 Sep 2013 In : Cell Reports. 4, 5, p. 853-860 8 p.

    Research output: Contribution to journalArticle

  50. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells

    Ulvestad, M., Nordell, P., Asplund, A., Rehnström, M., Jacobsson, S., Holmgren, G., Davidson, L., Brolén, G., Edsbagge, J., Björquist, P., Küppers-Munther, B. & Andersson, T. B. 1 Sep 2013 In : Biochemical Pharmacology. 86, 5, p. 691-702 12 p.

    Research output: Contribution to journalArticle

  51. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin

    Voss, M., Campbell, K., Saranzewa, N., Campbell, D. G., Hastie, C. J., Peggie, M. W., Martin-Granados, C., Prescott, A. R. & Cohen, P. T. W. 1 Sep 2013 In : Cell Cycle. 12, 17, p. 2876-2887 12 p.

    Research output: Contribution to journalArticle

  52. Defining the role of DAG, mitochondrial function, and lipid deposition in palmitate-induced proinflammatory signaling and its counter-modulation by palmitoleate

    Macrae, K., Stretton, C., Lipina, C., Blachnio-Zabielska, A., Baranowski, M., Gorski, J., Marley, A. & Hundal, H. S. Sep 2013 In : Journal of Lipid Research. 54, 9, p. 2366-2378 13 p.

    Research output: Contribution to journalArticle

  53. Mitogen-activated protein kinases in innate immunity

    Arthur, J. S. C. & Ley, S. C. Sep 2013 In : Nature Reviews Immunology. 13, 9, p. 679-692 14 p.

    Research output: Contribution to journalArticle

  54. DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA

    Ordureau, A., Enesa, K., Nanda, S., Le Francois, B., Peggie, M., Prescott, A., Albert, P. R. & Cohen, P. 23 Aug 2013 In : Journal of Biological Chemistry. 288, 34, p. 24569-24580 12 p.

    Research output: Contribution to journalArticle

  55. The β2 integrin–kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo

    Morrison, V. L., MacPherson, M., Savinko, T., San Lek, H., Prescott, A. & Fagerholm, S. C. 22 Aug 2013 In : Blood. 122, 8, p. 1428-1436 9 p.

    Research output: Contribution to journalArticle

  56. BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm

    Hobley, L., Ostrowski, A., Rao, F. V., Bromley, K. M., Porter, M., Prescott, A. R., Macphee, C. E., van Aalten, D. M. F. & Stanley-Wall, N. R. 13 Aug 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. 13600-13605 6 p.

    Research output: Contribution to journalArticle

  57. AMPK: a target for drugs and natural products with effects on both diabetes and cancer

    Hardie, D. G. Jul 2013 In : Diabetes. 62, 7, p. 2164-2172 9 p.

    Research output: Contribution to journalArticle

  58. X-ray crystal structure of ERK5 (MAPK7) in complex with a specific inhibitor

    Elkins, J. M., Wang, J., Deng, X., Pattison, M. J., Arthur, J. S. C., Erazo, T., Gomez, N., Lizcano, J. M., Gray, N. S. & Knapp, S. 13 Jun 2013 In : Journal of Medicinal Chemistry. 56, 11, p. 4413-4421 9 p.

    Research output: Contribution to journalArticle

  59. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 24 May 2013 In : Journal of Biological Chemistry. 288, 21, p. 14698-14708 11 p.

    Research output: Contribution to journalArticle

  60. IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages

    Pattison, M. J., MacKenzie, K. F., Elcombe, S. E. & Arthur, J. S. C. 21 May 2013 In : FEBS Letters. 587, 10, p. 1496-1503 8 p.

    Research output: Contribution to journalArticle

  61. Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

    Sinclair, L. V., Rolf, J., Emslie, E., Shi, Y-B., Taylor, P. M. & Cantrell, D. A. May 2013 In : Nature Immunology. 14, 5, p. 500-508 9 p.

    Research output: Contribution to journalArticle

  62. miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

    Remenyi, J., van den Bosch, M. W. M., Palygin, O., Mistry, R. B., McKenzie, C., Macdonald, A., Hutvagner, G., Arthur, J. S. C., Frenguelli, B. G. & Pankratov, Y. 26 Apr 2013 In : PLoS ONE. 8, 4, 14 p.e62509

    Research output: Contribution to journalArticle

  63. LKB1 and AMPK and the cancer-metabolism link - ten years after

    Hardie, D. G. & Alessi, D. R. 15 Apr 2013 In : BMC Biology. 11, 11 p.36

    Research output: Contribution to journalArticle

  64. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

    Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3 Apr 2013 In : EMBO Journal. 32, 7, p. 1008-22 15 p.

    Research output: Contribution to journalArticle

  65. AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

    Dandapani, M. & Hardie, D. G. Apr 2013 In : Biochemical Society Transactions. 41, 2, p. 687-693 7 p.

    Research output: Contribution to journalArticle

  66. AMPKα1: a glucose sensor that controls CD8 T-cell memory

    Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A. Apr 2013 In : European Journal of Immunology. 43, 4, p. 889-896 8 p.

    Research output: Contribution to journalArticle

  67. MSK1 and MSK2 inhibit lipopolysaccharide-induced prostaglandin production via an interleukin-10 feedback loop

    MacKenzie, K. F., Van den Bosch, M. W. M., Naqvi, S., Elcombe, S. E., McGuire, V. A., Reith, A. D., Blackshear, P. J., Dean, J. L. E. & Arthur, J. S. C. Apr 2013 In : Molecular and Cellular Biology. 33, 7, p. 1456-1467 12 p.

    Research output: Contribution to journalArticle

  68. The system L1 amino acid transporter (SLC7A5) facilitates nutrient signalling in mouse skeletal muscle in vivo

    Poncet, N. & Taylor, P. M. Apr 2013 In : FASEB Journal. 27, Suppl., 1 p.350.4

    Research output: Contribution to journalMeeting abstract

  69. Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

    Elcombe, S. E., Naqvi, S., Van den Bosch, M. W. M., MacKenzie, K. F., Cianfanelli, F., Brown, G. D. & Arthur, J. S. C. 22 Mar 2013 In : PLoS ONE. 8, 3, 15 p.e60086

    Research output: Contribution to journalArticle

  70. LKB1 Mediates the Development of Conventional and Innate T Cells via AMP-Dependent Kinase Autonomous Pathways

    Zarrouk, M., Rolf, J. & Cantrell, D. A. 22 Mar 2013 In : PLoS ONE. 8, 3, 9 p.e60217

    Research output: Contribution to journalArticle

  71. Sialoadhesin ligand expression identifies a subpopulation of Foxp3- T cells with a distinct activation and glycosylation profile

    Kidder, D., Richards, H. E., Ziltener, H. J., Garden, O. A. & Crocker, P. R. 15 Mar 2013 In : Journal of Immunology. 190, 6, p. 2593-2602 10 p.

    Research output: Contribution to journalArticle

  72. Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b β2-integrin-dependent signaling

    McMillan, S. J., Sharma, R. S., McKenzie, E. J., Richards, H. E., Zhang, J., Prescott, A. & Crocker, P. R. 14 Mar 2013 In : Blood. 121, 11, p. 2084-2094 11 p.

    Research output: Contribution to journalArticle

  73. Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors

    Horan, K. A., Hansen, K., Jakobsen, M. R., Holm, C. K., Søby, S., Unterholzner, L., Thompson, M., West, J. A., Iversen, M. B., Rasmussen, S. B., Ellermann-Eriksen, S., Kurt-Jones, E., Landolfo, S., Damania, B., Melchjorsen, J., Bowie, A. G., Fitzgerald, K. A. & Paludan, S. R. 1 Mar 2013 In : Journal of Immunology. 190, 5, p. 2311-2319 9 p.

    Research output: Contribution to journalArticle

  74. Global subcellular characterization of protein degradation using quantitative proteomics

    Larance, M., Ahmad, Y., Kirkwood, K. J., Ly, T. & Lamond, A. I. Mar 2013 In : Molecular & Cellular Proteomics. 12, 3, p. 638-650 13 p.

    Research output: Contribution to journalArticle

  75. Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

    Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. E2-E2 1 p.P577

    Research output: Contribution to journalMeeting abstract

  76. Hormonal regulation of the Salt-inducible Kinase (SIK), a key mediator that controls hepatic gluconeogenesis

    Patel, K., Goransson, O., Sutherland, C. & Sakamoto, K. Mar 2013

    Research output: Contribution to conferencePoster

  77. Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

    Nardi, F., Lipina, C., Magill, D. & Hundal, H. S. Mar 2013 In : Diabetic Medicine. 30, Suppl. 1, p. 49-49 1 p.P70

    Research output: Contribution to journalMeeting abstract

  78. Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

    Ruiz-Alcaraz, A. J., Lipina, C., Petrie, J. R., Murphy, M. J., Morris, A. D., Sutherland, C. & Cuthbertson, D. J. 28 Feb 2013 In : PLoS ONE. 8, 2, e56928

    Research output: Contribution to journalArticle

  79. Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence

    Mansur, D. S., Maluquer de Motes, C., Unterholzner, L., Sumner, R. P., Ferguson, B. J., Ren, H., Strnadova, P., Bowie, A. G. & Smith, G. L. 28 Feb 2013 In : PLoS Pathogens. 9, 2, e1003183

    Research output: Contribution to journalArticle

  80. Metabolism of inflammation limited by AMPK and pseudo-starvation

    O'Neill, L. A. J. & Hardie, D. G. 17 Jan 2013 In : Nature. 493, 7432, p. 346-355 10 p.

    Research output: Contribution to journalArticle

  81. PGE2 induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway

    Mackenzie, K. F., Clark, K., Naqvi, S., McGuire, V. A., Nöehren, G., Kristariyanto, Y., van den Bosch, M., Mudaliar, M., McCarthy, P. C., Pattison, M. J., Pedrioli, P. G. A., Barton, G. J., Toth, R., Prescott, A. & Arthur, J. S. C. 15 Jan 2013 In : Journal of Immunology. 190, 2, p. 565-577 13 p.

    Research output: Contribution to journalArticle

  82. Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo

    Belch, J. J. F., Akbar, N., Alapati, V., Petrie, J., Arthur, S. & Khan, F. Jan 2013 In : Microvascular Research. 85, p. 86-92 7 p.

    Research output: Contribution to journalArticle

  83. The role of amino acid transporters in nutrition

    Poncet, N. & Taylor, P. M. Jan 2013 In : Current Opinion in Clinical Nutrition and Metabolic Care. 16, 1, p. 57-65 9 p.

    Research output: Contribution to journalArticle

  84. AMPK: mediating the metabolic effects of salicylate-based drugs?

    Steinberg, G. R., Dandapani, M. & Hardie, D. G. 2013 In : Trends in Endocrinology and Metabolism. 24, 10, p. 481-487 7 p.

    Research output: Contribution to journalArticle

  85. Chronic exposure of astrocytes to interferon-alpha reveals molecular changes related to Aicardi-Goutieres syndrome

    Cuadrado, E., Jansen, M. H., Anink, J., De Filippis, L., Vescovi, A. L., Watts, C., Aronica, E., Hol, E. M. & Kuijpers, T. W. 2013 In : Brain. 136, 1, p. 245-258 14 p.

    Research output: Contribution to journalArticle

  86. Cross talk between the Akt and p38α pathways in macrophages downstream of toll-like receptor signaling

    McGuire, V. A., Gray, A., Monk, C. E., Santos, S. G., Lee, K., Aubareda, A., Crowe, J., Ronkina, N., Schwermann, J., Batty, I. H., Leslie, N. R., Dean, J. L. E., O'Keefe, S. J., Boothby, M., Gaestel, M. & Arthur, J. S. C. 2013 In : Molecular and Cellular Biology. 33, 21, p. 4152-4165 14 p.

    Research output: Contribution to journalArticle

  87. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

    MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 2013 In : Scientific Reports. 3, 1275

    Research output: Contribution to journalArticle

  88. Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival

    Song, J., Lokmic, Z., Lämmermann, T., Rolf, J., Wu, C., Zhang, X., Hallmann, R., Hannocks, M-J., Horn, N., Ruegg, M. A., Sonnenberg, A., Georges-Labouesse, E., Winkler, T. H., Kearney, J. F., Cardell, S. & Sorokin, L. 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 31, p. E2915-E2924 10 p.

    Research output: Contribution to journalArticle

  89. Insulin sensitising effects of monounsaturated and polyunsaturated fatty acids in skeletal muscle cells

    Nardi, F., Lipina, C., Magill, D. & Hundal, H. S. 2013

    Research output: Contribution to conferencePoster

  90. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

    Groves, M. J., Johnson, C. E., James, J., Prescott, A. R., Cunningham, J., Haydock, S., Pepper, C., Fegan, C., Pirrie, L., Westwood, N. J., Coates, P. J., Ganley, I. G. & Tauro, S. 2013 In : British Journal of Cancer. 109, October, p. 2432=2444 13 p.

    Research output: Contribution to journalArticle

  91. Phospholipase C-eta 2 is required for retinoic acid-stimulated neurite growth

    Popovics, P., Gray, A., Arastoo, M., Finelli, D. K., Tan, A. J. L. & Stewart, A. J. 2013 In : Journal of Neurochemistry. 124, 5, p. 632-644 13 p.

    Research output: Contribution to journalArticle

  92. Phosphorylation of the actin binding protein drebrin at S647 is regulated by neuronal activity and PTEN

    Kreis, P., Hendricusdottir, R., Kay, L., Papageorgiou, I. E., van Diepen, M., Mack, T., Ryves, J., Harwood, A., Leslie, N. R., Kann, O., Parsons, M. & Eickholt, B. J. 2013 In : PLoS ONE. 8, 8, e71957

    Research output: Contribution to journalArticle

  93. PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism

    Gericke, A., Leslie, N. R., Lösche, M. & Ross, A. H. 2013 Lipid-mediated protein signaling. Capelluto, D. S. (ed.). Springer Netherlands, p. 85-104 20 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  94. RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

    Arthur, J. S. C. & 21 others Park, J., Al-Ramahi, I., Tan, Q., Mollema, N., Diaz-Garcia, J. R., Gallego-Flores, T., Lu, H-C., Lagalwar, S., Duvick, L., Kang, H., Lee, Y., Jafar-Nejad, P., Sayegh, L. S., Richman, R., Liu, X., Gao, Y., Shaw, C. A., Orr, H. T., Westbrook, T. F., Botas, J. & Zoghbi, H. Y. 2013 In : Nature. 498, 7454, p. 325-331 7 p.

    Research output: Contribution to journalArticle

  95. Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

    Fullerton, M. D., Galic, S., Marcinko, K., Sikkema, S., Pulinilkunnil, T., Chen, Z-P., O'Neill, H. M., Ford, R. J., Palanivel, R., O'Brien, M., Hardie, D. G., Macaulay, S. L., Schertzer, J. D., Dyck, J. R. B., van Denderen, B. J., Kemp, B. E. & Steinberg, G. R. 2013 In : Nature Medicine. 19, p. 1649-1654 6 p.

    Research output: Contribution to journalArticle

  96. The impact of KLF2 modulation on the transcriptional program and function of CD8 T Cells

    Preston, G. C., Feijoo-Carnero, C., Schurch, N., Cowling, V. H. & Cantrell, D. A. 2013 In : PLoS ONE. 8, 10, 16 p.e77537

    Research output: Contribution to journalArticle

  97. The LKB1-AMPK Pathway-Friend or Foe in Cancer?

    Hardie, D. G. 2013 In : Cancer Cell. 23, 2, p. 131-132 2 p.

    Research output: Contribution to journalEditorial

  98. The specificity of the interaction between αB-crystallin and desmin filaments and its impact on filament aggregation and cell viability

    Elliott, J. L., Der Perng, M., Prescott, A. R., Jansen, K. A., Koenderink, G. H. & Quinlan, R. A. 2013 In : Philosophical Transactions of the Royal Society B - Biological Sciences. 368, 1617, 15 p.20120375

    Research output: Contribution to journalArticle

  99. Two Phases of Inflammatory Mediator Production Defined by the Study of IRAK2 and IRAK1 Knock-in Mice

    Pauls, E., Nanda, S. K., Smith, H., Toth, R., Arthur, J. S. C. & Cohen, P. 2013 In : Journal of Immunology. 1203268

    Research output: Contribution to journalArticle

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