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Cell Signalling & Immunology

  1. NEU3 sialidase as a marker of insulin sensitivity: Regulation by fatty acids

    Lipina, C., Nardi, F., Grace, H. & Hundal, H. S. 1 Sep 2015 In : Cellular Signalling. 27, 9, p. 1742-1750 9 p.

    Research output: Contribution to journalArticle

  2. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes

    Preston, G. C., Sinclair, L. V., Kaskar, A., Hukelmann, J. L., Navarro, M., Ferrero, I., MacDonald, H. R., Cowling, V. H. & Cantrell, D. A. 4 Aug 2015 In : EMBO Journal. 34, 15, p. 2008-2024 17 p.

    Research output: Contribution to journalArticle

  3. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

    Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. M. K. 1 Aug 2015 In : EMBO Reports. 16, 8, p. 939-954 16 p.

    Research output: Contribution to journalArticle

  4. Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

    Rog-Zielinska, E. A., Craig, M. A., Manning, J. R., Richardson, R. V., Gowans, G. J., Dunbar, D. R., Gharbi, K., Kenyon, C. J., Holmes, M. C., Hardie, D. G., Smith, G. L. & Chapman, K. E. 1 Jul 2015 In : Cell Death & Differentiation. 22, 7, p. 1106-1116 11 p.

    Research output: Contribution to journalArticle

  5. AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle

    Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U. Jul 2015 In : Hypertension. 66, 1, p. 108-116 9 p.

    Research output: Contribution to journalArticle

  6. Suppression of interferon β gene transcription by inhibitors of bromodomain and extra-terminal (BET) family members

    Malik, N., Vollmer, S., Nanda, S. K., Lopez-Pelaez, M., Prescott, A., Gray, N. & Cohen, P. 15 Jun 2015 In : Biochemical Journal. 468, 3, p. 363-372 10 p.

    Research output: Contribution to journalArticle

  7. Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

    Swamy, M., Abeler-Dörner, L., Chettle, J., Mahlakõiv, T., Goubau, D., Chakravarty, P., Ramsay, G., Reis e Sousa, C., Staeheli, P., Blacklaws, B. A., Heeney, J. L. & Hayday, A. C. 19 May 2015 In : Nature Communications. 6, 12 p., 7090

    Research output: Contribution to journalArticle

  8. PT-1 selectively activates AMPK-γ 1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain

    Jensen, T. E., Ross, F. A., Kleinert, M., Sylow, L., Knudsen, J. R., Gowans, G. J., Hardie, D. G. & Richter, E. A. May 2015 In : Biochemical Journal. 467, 3, p. 461-472 12 p.

    Research output: Contribution to journalArticle

  9. AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

    Hardie, D. G. Apr 2015 In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  10. Proteasomal modulation of cellular SNAT2 (SLC38A2) abundance and function by unsaturated fatty acid availability

    Nardi, F., Hoffmann, T. M., Stretton, C., Cwiklinski, E., Taylor, P. M. & Hundal, H. S. 27 Mar 2015 In : Journal of Biological Chemistry. 290, 13, p. 8173-8184 12 p.

    Research output: Contribution to journalArticle

  11. SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation

    Varshney, D., Vavrova-Anderson, J., Oler, A. J., Cowling, V. H., Cairns, B. R. & White, R. J. 23 Mar 2015 In : Nature Communications. 6, 12 p., 6569

    Research output: Contribution to journalArticle

  12. Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation

    Wypijewski, K. J., Tinti, M., Chen, W., Lamont, D., Ashford, M. L. J., Calaghan, S. C. & Fuller, W. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 596-608 13 p.

    Research output: Contribution to journalArticle

  13. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation

    Stone, E. L., Pepper, M., Katayama, C. D., Kerdiles, Y. M., Lai, C-Y., Emslie, E., Lin, Y. C., Yang, E., Goldrath, A. W., Li, M. O., Cantrell, D. A. & Hedrick, S. M. 17 Feb 2015 In : Immunity. 42, 2, p. 239-251 13 p.

    Research output: Contribution to journalArticle

  14. Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes

    Spinelli, L., Black, F. M., Berg, J. N., Eickholt, B. J. & Leslie, N. R. Feb 2015 In : Journal of Medical Genetics. 52, 2, p. 128-134 7 p.

    Research output: Contribution to journalArticle

  15. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

    Pirkmajer, S., Kulkarni, S. S., Tom, R. Z., Ross, F. A., Hawley, S. A., Hardie, D. G., Zierath, J. R. & Chibalin, A. V. Feb 2015 In : Diabetes. 64, 2, p. 360-369 10 p.

    Research output: Contribution to journalArticle

  16. Mitogen and stress-activated kinases 1/2 regulate ischemia-induced hippocampal progenitor cell proliferation and neurogenesis

    Karelina, K., Liu, Y., Alzate-Correa, D., Wheaton, K. L., Hoyt, K. R., Arthur, J. S. C. & Obrietan, K. 29 Jan 2015 In : Neuroscience. 285, p. 292-302 11 p.

    Research output: Contribution to journalArticle

  17. RAB1A promotes Vaccinia virus replication by facilitating the production of intracellular enveloped virions

    Pechenick Jowers, T., Featherstone, R. J., Reynolds, D. K., Brown, H. K., James, J., Prescott, A., Haga, I. R. & Beard, P. M. 15 Jan 2015 In : Virology. 475, p. 66-73 8 p.

    Research output: Contribution to journalArticle

  18. The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases

    Ozanne, J., Prescott, A. R. & Clark, K. 15 Jan 2015 In : Biochemical Journal. 465, 2, p. 271-279 9 p.

    Research output: Contribution to journalArticle

  19. PTEN inhibitors: an evaluation of current compounds

    Spinelli, L., Lindsay, Y. E. & Leslie, N. R. Jan 2015 In : Advances in Biological Regulation. 57, p. 102-111 10 p.

    Research output: Contribution to journalArticle

  20. Environmental and metabolic sensors that control T cell biology

    Ramsay, G. & Cantrell, D. 2015 In : Frontiers in Immunology. 6, 8 p., 99

    Research output: Contribution to journalArticle

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