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Clinical Trials Unit

  1. Detection in blood of autoantibodies to tumour antigens as a case-finding method in lung cancer using the EarlyCDT®-Lung Test (ECLS): study protocol for a randomized controlled trial

    Sullivan, F. M., Farmer, E., Mair, F. S., Treweek, S., Kendrick, D., Jackson, C., Robertson, C., Briggs, A., McCowan, C., Bedford, L., Young, B., Vedhara, K., Gallant, S., Littleford, R., Robertson, J., Sewell, H., Dorward, A., Sarvesvaran, J. & Schembri, S. 11 Mar 2017 In : BMC Cancer. 17, p. 1-10 10 p., 187

    Research output: Contribution to journalArticle

  2. Achieving Good Outcomes for Asthma Living (GOAL): mixed methods feasibility and pilot cluster randomised controlled trial of a practical intervention for eliciting, setting and achieving goals for adults with asthma

    Hoskins, G., Williams, B., Abhyankar, P., Donnan, P., Duncan, E., Pinnock, H., van der Pol, M., Rauchhaus, P., Taylor, A. & Sheikh, A. 8 Dec 2016 In : Trials. 17, p. 1-17 17 p., 584

    Research output: Contribution to journalArticle

  3. Spironolactone for people aged 70 or over with osteoarthritic knee pain: a proof-of-concept trial

    McMurdo, M. E. T., Sumukadas, D., Donnan, P. T., Cvoro, V., Rauchhaus, P., Argo, I., Waldie, H., Littleford, R., Struthers, A. D. & Witham, M. D. May 2016 In : Arthritis Care & Research. 68, 5, p. 716-721 6 p.

    Research output: Contribution to journalArticle

  4. Long-term effect of lithium maintenance therapy on estimated glomerular filtration rate in patients with affective disorders: a population-based cohort study

    Clos, S., Rauchhaus, P., Severn, A., Cochrane, L. & Donnan, P. T. Dec 2015 In : Lancet Psychiatry. 2, 12, p. 1075-1083 9 p.

    Research output: Contribution to journalArticle

  5. Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial

    Witham, M. D., Band, M. M., Littleford, R. C., Avenell, A., Soiza, R. L., McMurdo, M. E. T., Sumukadas, D., Ogston, S. A., Lamb, E. J., Hampson, G., McNamee, P. & BiCARB study group 1 Aug 2015 In : Trials. 16, 9 p., 326

    Research output: Contribution to journalArticle

  6. Making randomised trials more efficient: Report of the first meeting to discuss the Trial Forge platform

    Treweek, S. , Altman, D. G. , Bower, P. , Campbell, M. , Chalmers, I. , Cotton, S. , Craig, P. , Crosby, D. , Davidson, P. , Devane, D. , Duley, L. , Dunn, J. , Elbourne, D. , Farrell, B. , Gamble, C. , Gillies, K. , Hood, K. , Lang, T. , Littleford, R. , Loudon, K. & 11 others McDonald, A., McPherson, G., Nelson, A., Norrie, J., Ramsay, C., Sandercock, P., Shanahan, D. R., Summerskill, W., Sydes, M., Williamson, P. & Clarke, M. 5 Jun 2015 In : Trials. 16, 10 p., 261

    Research output: Contribution to journalArticle

  7. Technical assessment of whole body angiography and cardiac function within a single MRI examination

    Gandy, S. J., Lambert, M., Belch, J. J. F., Cavin, I. D., Crowe, E., Littleford, R., Macfarlane, J. A., Matthew, S. Z., Martin, P., Nicholas, R. S., Struthers, A. D., Sullivan, F., Waugh, S. A., White, R. D., Weir-McCall, J. R. & Houston, J. G. Jun 2015 In : Clinical Radiology. 70, 6, p. 595-603 9 p.

    Research output: Contribution to journalArticle

  8. Cognitive behaviour therapy plus aerobic exercise training to increase activity in patients with myotonic dystrophy type 1 (DM1) compared to usual care (OPTIMISTIC): Study protocol for randomised controlled trial

    van Engelen, B. , Abghari, S. , Aschrafi, A. , Bouman, S. , Cornelissen, Y. , Glennon, J. , Groot, P. , Heerschap, A. , Heskamp, L. , Heskes, T. , Kapusta, K. , Klerks, E. , Knoop, H. , Maas, D. , Okkersen, K. , Poelmans, G. , Rahmadi, R. , van Nimwegen, M. , Gorman, G. , Moreno, C. J. & 37 others Lochmüller, H., Trenell, M., van Laar, S., Wood, L., Schoser, B., Wenninger, S., Schüller, A., Auguston, R., Baptiste, L., Barau, C., Bassez, G., Chevalier, P., Couppey, F., Delmas, S., Deux, J. F., Dogan, C., Hamadouche, A., Hankiewicz, K., Lhermet, L., Minier, L., Rialland, A., Schmitz, D., Monckton, D. G., Cumming, S. A., Adam, B., Donnan, P., Hannah, M., Hogarth, F., Littleford, R., McKenzie, E., Rauchhaus, P., Wilkie, E., Williamson, J., Catt, M., Dittrich, J., Schwalber, A. & Treweek, S. 23 May 2015 In : Trials. 16, 224, 19 p., 224

    Research output: Contribution to journalArticle

  9. Finding your feet: The development of a podiatry intervention to reduce falls in care home residents

    Wylie, G., Young, Z., Littleford, R., Sullivan, F., Coyle, J., Williams, B., Menz, H. B., Ogston, S. & Morris, J. 20 Apr 2015 In : Journal of Foot and Ankle Research. 8, Suppl 1, p. 1-2 2 p., A7

    Research output: Contribution to journalMeeting abstract

  10. Reflecting on the methodological challenge of recruiting older care home residents to podiatry research

    Wylie, G., Young, Z., Littleford, R., Sullivan, F., Williams, B., Menz, H. B., Ogston, S. & Morris, J. 20 Apr 2015 In : Journal of Foot and Ankle Research. 8, Suppl 1, p. 1-2 2 p., A10

    Research output: Contribution to journalMeeting abstract

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