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CLS/MRI Molecular Medicine

  1. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. Jul 2015 In : Journal of Investigative Dermatology. 135, 7, p. 1919-1921 3 p.

    Research output: Contribution to journalLetter

  2. Keratins and skin disease

    Knöbel, M., O’Toole, E. A. & Smith, F. J. D. Jun 2015 In : Cell and Tissue Research. 360, 3, p. 583-589 7 p.

    Research output: Contribution to journalArticle

  3. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    Knatko, E. V., Ibbotson, S. H., Zhang, Y., Higgins, M., Fahey, J. W., Talalay, P., Dawe, R. S., Ferguson, J., Huang, J. T-J., Clarke, R., Zheng, S., Saito, A., Kalra, S., Benedict, A. L., Honda, T., Proby, C. M. & Dinkova-Kostova, A. T. Jun 2015 In : Cancer Prevention Research. 8, 6, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  4. Mutations in GJB6 causing phenotype resembling pachyonychia congenita

    Hale, G. I., Wilson, N. J., Smith, F. J. D., Wylie, G., Schwartz, M. E. & Zamiri, M. May 2015 In : British Journal of Dermatology. 172, 5, p. 1447-1449 3 p.

    Research output: Contribution to journalLetter

  5. Loss-of-function mutations in the gene encoding filaggrin underlie a Japanese family with food-dependent exercise-induced anaphylaxis

    Mizuno, O., Nomura, T., Ohguchi, Y., Suzuki, S., Nomura, Y., Hamade, Y., Hoshina, D., Sandilands, A., Akiyama, M., McLean, W. H. I., Abe, R. & Shimizu, H. Apr 2015 In : Journal of the European Academy of Dermatology and Venereology. 29, 4, p. 805-808 4 p.

    Research output: Contribution to journalArticle

  6. Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

    Kelleher, M., Dunn-Galvin, A., Hourihane, J. O. B., Murray, D., Campbell, L. E., McLean, W. H. I. & Irvine, A. D. Apr 2015 In : Journal of Allergy and Clinical Immunology. 135, 4, p. 930-935.e1 6 p.

    Research output: Contribution to journalArticle

  7. Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads

    Lin, Z. , Zhao, J. , Nitoiu, D. , Scott, C. A. , Plagnol, V. , Smith, F. J. D. , Wilson, N. J. , Cole, C. , Schwartz, M. E. , McLean, W. H. I. , Wang, H. , Feng, C. , Duo, L. , Zhou, E. Y. , Ren, Y. , Dai, L. , Chen, Y. , Zhang, J. , Xu, X. , O'Toole, E. A. & 2 others Kelsell, D. P. & Yang, Y. 5 Mar 2015 In : American Journal of Human Genetics. 96, 3, p. 440-447 8 p.

    Research output: Contribution to journalArticle

  8. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

    Brown, S. J. & 38 others Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I., Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S. & Cordell, H. J. 8 Jan 2015 In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticle

  9. Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

    Brough, H. A., Liu, A. H., Sicherer, S., Makinson, K., Douiri, A., Brown, S. J., Stephens, A. C., McLean, W. H. I., Turcanu, V., Wood, R. A., Jones, S. M., Burks, W., Dawson, P., Stablein, D., Sampson, H. & Lack, G. Jan 2015 In : Journal of Allergy and Clinical Immunology. 135, 1, p. 164-170.e4 11 p.

    Research output: Contribution to journalArticle

  10. PCQoL: a quality of life assessment measure for Pachyonychia congenita

    Abbas, M., Schwartz, M. E., Smith, F. J. D., McLean, W. H. I. & Hull, P. R. 2015 In : Journal of Cutaneous Medicine and Surgery. 19, 1, p. 57-65 9 p.

    Research output: Contribution to journalArticle

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