CMDN Molecular Medicine

Modulation of p53 C-terminal acetylation by mdm2, p14^ARF, and cytoplasmic SirT2

van Leeuwen, I. M. M., Higgins, M., Campbell, J., McCarthy, A. R., Sachweh, M. C. C., Navarro, A. M. & Lain, S. Apr-2013 In : Molecular Cancer Therapeutics. 12, 4, p. 471-480, 10 p.

Research output: Contribution to journal › Article

Recessive mutations in the gene encoding frizzled 6 cause twenty nail dystrophy: Expanding the differential diagnosis for pachyonychia congenita

Wilson, N. J., Hansen, C. D., Azkur, D., Kocabas, C. N., Metin, A., Coskun, Z., Schwartz, M. E., Hull, P. R., McLean, W. H. I. & Smith, F. J. D. Apr-2013 In : Journal of Dermatological Science. 70, 1, p. 58-60, 3 p.

Research output: Contribution to journal › Letter

Reliability and validity of genotyping filaggrin null mutations

Margolis, D. J., Apter, A. J., Mitra, N., Gupta, J., Hoffstad, O., Papadopoulos, M., Rebbeck, T. R., MacCallum, S., Campbell, L. E., Sandilands, A. & McLean, W. H. I. Apr-2013 In : Journal of Dermatological Science. 70, 1, p. 67-68, 2 p.

Research output: Contribution to journal › Letter

Tenovin-D3, a novel small-molecule inhibitor of sirtuin SirT2, increases p21 (CDKN1A) expression in a p53-independent manner

McCarthy, A. R., Sachweh, M. C. C., Higgins, M., Campbell, J., Drummond, C. J., van Leeuwen, I. M. M., Pirrie, L., Ladds, M. J. G. W., Westwood, N. J. & Lain, S. Apr-2013 In : Molecular Cancer Therapeutics. 12, 4, p. 352-360, 9 p.

Research output: Contribution to journal › Article

Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information

Baclig, A. C., Bakker Schut, T. C., O'Regan, G. M., Irvine, A. D., McLean, W. H. I., Puppels, G. J. & Caspers, P. J. Mar-2013 In : Journal of Raman Spectroscopy. 44, 3, p. 340-345, 6 p.

Research output: Contribution to journal › Article

p53 is activated in response to disruption of the pre-mRNA splicing machinery

Allende-Vega, N., Dayal, S., Agarwala, U., Sparks, A., Bourdon, J-C. & Saville, M. K. 3-Jan-2013 In : Oncogene. 32, 1, p. 1-14, 14 p.

Research output: Contribution to journal › Article

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 1-Jan-2013 In : Scientific Reports. 3, 1275

Research output: Contribution to journal › Article

A nonsense mutation in the mattrin gene causes the matted mouse phenotype and is a predisposing gene for atopic dermatitis in humans

Goh, C. S., Saunders, S. P., Cole, C., Weidinger, S., Baurecht, H., Lee, Y., Reynolds, N. J., Barker, J. N., Cordell, H. J., Brown, S. J., Irvine, A. D., McLean, I., Sandilands, A. & Fallon, P. G. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S145, 1 p., 854

Research output: Contribution to journal › Meeting abstract

Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy

Allen, E. H. A., Atkinson, S. D., Liao, H., Moore, J. E., Pedrioli, D. M. L., Smith, F. J. D., McLean, W. H. I. & Moore, C. B. T. 2013 In : Investigative Ophthalmology & Visual Science. 54, 1, p. 494-502, 9 p.

Research output: Contribution to journal › Article

Cutaneous squamous cell carcinoma derived cell lines are more sensitive to the proteasome inhibitor bortezomib than normal skin cells

Koerver, L., Tura, Z. H., Leigh, I. M., South, A. P. & Saville, M. K. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S183, 1 p.

Research output: Contribution to journal › Meeting abstract