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  1. Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design

    Wyatt, P. G. , Woodhead, A. J. , Berdini, V. , Boulstridge, J. A. , Carr, M. G. , Cross, D. M. , Davis, D. J. , Devine, L. A. , Early, T. R. , Feltell, R. E. , Lewis, E. J. , McMenamin, R. L. , Navarro, E. F. , O'Brien, M. A. , O'Reilly, M. , Reule, M. , Saxty, G. , Seavers, L. C. A. , Smith, D-M. , Squires, M. S. & 3 others Trewartha, G., Walker, M. T. & Woolford, A. J. -A. 28 Aug 2008 In : Journal of Medicinal Chemistry. 51, 16, p. 4986-4999 14 p.

    Research output: Contribution to journalArticle

  2. Carrier erythrocyte entrapped thymidine phosphorylas etherapy for MNGIE

    Moran, N. F., Bain, M. D., Muqit, M. M. K. & Bax, B. E. 26 Aug 2008 In : Neurology. 71, 9, p. 686-688 3 p.

    Research output: Contribution to journalScientific review

  3. Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death

    Pathak, S., Dorfmueller, H. C., Borodkin, V. S. & van Aalten, D. M. F. 25 Aug 2008 In : Chemistry & Biology. 15, 8, p. 799-807 9 p.

    Research output: Contribution to journalArticle

  4. COMP 90-The trouble with translating information into medicines: strategies for embracing serendipity and uncertainty

    Hopkins, A. L. 17 Aug 2008 In : Abstracts of Papers of the American Chemical Society. 236, p. - 1 p.

    Research output: Contribution to journalBook/Film/Article review

  5. Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts

    Bru, T., Clarke, C., McGrew, M. J., Sang, H. M., Wilmut, I. & Blow, J. J. 15 Aug 2008 In : Experimental Cell Research. 314, 14, p. 2634-2642 9 p.

    Research output: Contribution to journalArticle

  6. Regulation of gene expression by hypoxia

    Kenneth, N. S. & Rocha, S. 15 Aug 2008 In : Biochemical Journal. 414, 1, p. 19-29 11 p.

    Research output: Contribution to journalScientific review

  7. Orientation dependence in fluorescent energy transfer between Cy3 and Cy5 terminally attached to double-stranded nuclelic acids

    Iqbal, A., Arslan, S., Okumus, B., Wilson, T. J., Giraud, G., Norman, D. G., Ha, T. & Lilley, D. M. J. 12 Aug 2008 In : Proceedings of the National Academy of Sciences of the United States of America. 105, 32, p. 11176-11181 6 p.

    Research output: Contribution to journalArticle

  8. CD33-related sialic-acid-binding immunoglobulin-like lectins in health and disease

    McMillan, S. J. & Crocker, P. R. 11 Aug 2008 In : Carbohydrate Research. 343, 12, p. 2050-2056 7 p.

    Research output: Contribution to journalArticle

  9. Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

    Lamb, D., Schuettelkopf, A. W., van Aalten, D. M. F. & Brighty, D. W. 4 Aug 2008 In : Retrovirology. 5, p. - 14 p.70

    Research output: Contribution to journalArticle

  10. Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage

    Vazquez-Martin, C., Rouse, J. & Cohen, P. T. W. Aug 2008 In : FEBS Journal. 275, 16, p. 4211-4221 11 p.

    Research output: Contribution to journalArticle

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