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  1. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita

    Leachman, S. A., Hickerson, R. P., Hull, P. R., Smith, F. J. D., Milstone, L. M., Lane, E. B., Bale, S. J., Roop, D. R., McLean, W. H. I. & Kaspar, R. L. Sep 2008 In : Journal of Dermatological Science. 51, 3, p. 151-157 7 p.

    Research output: Contribution to journalScientific review

  2. DsbA plays a critical and multifaceted role in the production of secreted virulence factors by the phytopathogen Erwinia carotovora subsp atroseptica

    Coulthurst, S. J., Lilley, K. S., Hedley, P. E., Liu, H., Toth, I. K. & Salmond, G. P. C. 29 Aug 2008 In : Journal of Biological Chemistry. 283, 35, p. 23739-23753 15 p.

    Research output: Contribution to journalArticle

  3. Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway

    Signorell, A., Rauch, M., Jelk, J., Ferguson, M. A. J. & Buetikofer, P. 29 Aug 2008 In : Journal of Biological Chemistry. 283, 35, p. 23636-23644 9 p.

    Research output: Contribution to journalArticle

  4. Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design

    Wyatt, P. G. , Woodhead, A. J. , Berdini, V. , Boulstridge, J. A. , Carr, M. G. , Cross, D. M. , Davis, D. J. , Devine, L. A. , Early, T. R. , Feltell, R. E. , Lewis, E. J. , McMenamin, R. L. , Navarro, E. F. , O'Brien, M. A. , O'Reilly, M. , Reule, M. , Saxty, G. , Seavers, L. C. A. , Smith, D-M. , Squires, M. S. & 3 others Trewartha, G., Walker, M. T. & Woolford, A. J. -A. 28 Aug 2008 In : Journal of Medicinal Chemistry. 51, 16, p. 4986-4999 14 p.

    Research output: Contribution to journalArticle

  5. Carrier erythrocyte entrapped thymidine phosphorylas etherapy for MNGIE

    Moran, N. F., Bain, M. D., Muqit, M. M. K. & Bax, B. E. 26 Aug 2008 In : Neurology. 71, 9, p. 686-688 3 p.

    Research output: Contribution to journalScientific review

  6. Chemical dissection of the link between streptozotocin, O-GlcNAc, and pancreatic cell death

    Pathak, S., Dorfmueller, H. C., Borodkin, V. S. & van Aalten, D. M. F. 25 Aug 2008 In : Chemistry & Biology. 15, 8, p. 799-807 9 p.

    Research output: Contribution to journalArticle

  7. COMP 90-The trouble with translating information into medicines: strategies for embracing serendipity and uncertainty

    Hopkins, A. L. 17 Aug 2008 In : Abstracts of Papers of the American Chemical Society. 236, p. - 1 p.

    Research output: Contribution to journalBook/Film/Article review

  8. Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts

    Bru, T., Clarke, C., McGrew, M. J., Sang, H. M., Wilmut, I. & Blow, J. J. 15 Aug 2008 In : Experimental Cell Research. 314, 14, p. 2634-2642 9 p.

    Research output: Contribution to journalArticle

  9. Regulation of gene expression by hypoxia

    Kenneth, N. S. & Rocha, S. 15 Aug 2008 In : Biochemical Journal. 414, 1, p. 19-29 11 p.

    Research output: Contribution to journalScientific review

  10. Orientation dependence in fluorescent energy transfer between Cy3 and Cy5 terminally attached to double-stranded nuclelic acids

    Iqbal, A., Arslan, S., Okumus, B., Wilson, T. J., Giraud, G., Norman, D. G., Ha, T. & Lilley, D. M. J. 12 Aug 2008 In : Proceedings of the National Academy of Sciences of the United States of America. 105, 32, p. 11176-11181 6 p.

    Research output: Contribution to journalArticle

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