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  1. Erk5 is a key regulator of naïve-­primed transition and Embryonic Stem Cell identity

    Williams, C., Fernandez-Alonso, R., Wang, J., Toth, R., Gray, N. S. & Findlay, G. 16 Aug 2016 In : Cell Reports. 16, 7, p. 1820-1828 9 p.

    Research output: Contribution to journalArticle

  2. A quasi-cyclic RNA nano-scale molecular object constructed using kink turns

    Huang, L. & Lilley, D. M. J. 7 Sep 2016 In : Nanoscale. 8, 33, p. 15189-15195 7 p.

    Research output: Contribution to journalArticle

  3. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

    Rivas, M. A. , Graham, D. , Sulem, P. , Stevens, C. , Desch, A. N. , Goyette, P. , Gudbjartsson, D. , Jonsdottir, I. , Thorsteinsdottir, U. , Degenhardt, F. , Mucha, S. , Kurki, M. I. , Li, D. , D'Amato, M. , Annese, V. , Vermeire, S. , Weersma, R. K. , Halfvarson, J. , Paavola-Sakki, P. & 71 others Lappalainen, M., Lek, M., Cummings, B., Tukiainen, T., Haritunians, T., Halme, L., Koskinen, L. L. E., Ananthakrishnan, A. N., Luo, Y., Heap, G. A., Visschedijk, M. C., MacArthur, D. G., Neale, B. M., Ahmad, T., Anderson, C. A., Brant, S. R., Duerr, R. H., Silverberg, M. S., Cho, J. H., Palotie, A., Saavalainen, P., Kontula, K., Färkkilä, M., McGovern, D. P. B., Franke, A., Stefansson, K., Rioux, J. D., Xavier, R. J., Daly, M. J., Barrett, J., De Lane, K., Edwards, C., Hart, A., Hawkey, C., Jostins, L., Kennedy, N., Lamb, C., Lee, J., Lees, C., Mansfield, J., Mathew, C., Mowatt, C., Newman, B., Nimmo, E., Parkes, M., Pollard, M., Prescott, N., Randall, J., Rice, D., Satsangi, J., Simmons, A., Tremelling, M., Uhlig, H., Wilson, D., Abraham, C., Achkar, J. P., Bitton, A., Boucher, G., Croitoru, K., Fleshner, P., Glas, J., Kugathasan, S., Limbergen, J. V., Milgrom, R., Proctor, D., Regueiro, M., Schumm, P. L., Sharma, Y., Stempak, J. M., Targan, S. R. & Wang, M. H. 9 Aug 2016 In : Nature Communications. 7, 12342

    Research output: Contribution to journalArticle

  4. Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding

    Freeman, A. D. J., Stevens, M., Declais, A. C., Leahy, A., Mackay, K., El Mkami, H., Lilley, D. M. J. & Norman, D. G. 2 Aug 2016 In : Biochemistry. 55, 30, p. 4166-4172 7 p.

    Research output: Contribution to journalArticle

  5. mRNA Cap methylation in pluripotency and differentiation

    Grasso, L., Suska, O., Davidson, L., Gonatopoulos-Pournatzis, T., Williamson, R., Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M. P. & Cowling, V. H. 2 Aug 2016 In : Cell Reports. 16, 5, p. 1352-1365 14 p.

    Research output: Contribution to journalArticle

  6. AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

    Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G. 1 Aug 2016 In : Molecular Cancer Research. p. 683-695 13 p.

    Research output: Contribution to journalArticle

  7. Mutations in POGLUT1 in Galli-Galli /Dowling Degos-disease

    Wilson, N. J., Cole, C., Kroboth, K., Hunter, W. N., Mann, J. A., Irwin McLean, W. H., Kernland Lang, K., Beltraminelli, H., Sabroe, R. A., Tiffin, N., Sobey, G. J., Borradori, L., Simpson, E. & Smith, F. J. D. 1 Aug 2016 In : British Journal of Dermatology.

    Research output: Contribution to journalLetter

  8. Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

    Varshney, D., Petit, A-P., Bueren-Calabuig, J. A., Jansen, C., Fletcher, D. A., Peggie, M., Weidlich, S., Scullion, P., Pisliakov, A. V. & Cowling, V. H. 15 Jul 2016 In : Nucleic Acids Research. 14 p.

    Research output: Contribution to journalArticle

  9. MSAViewer: interactive JavaScript visualization of multiple sequence alignments

    Yachdav, G., Wilzbach, S., Rauscher, B., Sheridan, R., Sillitoe, I., Procter, J., Lewis, S. E., Rost, B. & Goldberg, T. 13 Jul 2016 In : Bioinformatics. 3 p.

    Research output: Contribution to journalArticle

  10. The European Union's investment and future role in dermatologic research

    Leigh, I. M. Jul 2016 In : Journal of Investigative Dermatology. 136, 7, p. 1307-1310 4 p.

    Research output: Contribution to journalEditorial

  11. Establishment of a high-throughput setup for screening small molecules that modulate c-di-GMP signaling in Pseudomonas aeruginosa

    Rugjee, K. N., An, S. & Ryan, R. P. 30 Jun 2016 In : JoVE: Journal of Visualized Experiments. 112, 7 p., e54115

    Research output: Contribution to journalArticle

  12. Heat Shock Factor 1 is a Substrate for p38 Mitogen-Activated Protein Kinases

    Dayalan Naidu, S., Sutherland, C., Zhang, Y., Risco, A., de la Vega, L., Caunt, C. J., Hastie, C. J., Lamont, D. J., Torrente, L., Chowdhry, S., Benjamin, I. J., Keyse, S. M., Cuenda, A. & Dinkova-Kostova, A. T. 27 Jun 2016 In : Molecular and Cellular Biology.

    Research output: Contribution to journalArticle

  13. The genome of the yellow potato cyst nematode Globodera rostochiensis reveals insights into the basis of parasitism and virulence

    Eves-van den Akker, S. , Laetsch, D. R. , Thorpe, P. , Lilley, C. J. , Danchin, E. G. J. , Da Rocha, M. , Rancurel, C. , Holroyd, N. E. , Cotton, J. , Szitenberg, A. , Grenier, E. , Montarry, J. , Mimee, B. , Duceppe, M-O. , Boyes, I. , Marvin, J. M. C. , Jones, L. M. , Yusup, H. B. , Lafond-Lapalme, J. & 15 others Esquibet, M., Sabeh, M., Rott, M., Overmars, H., Finkers-Tomczak, A., Smant, G., Koutsovoulos, G., Blok, V., Mantelin, S., Cock, P. J. A., Phillips, W., Henrissat, B., Urwin, P. E., Blaxter, M. & Jones, J. T. 10 Jun 2016 In : Genome Biology. 17, 23 p., 124

    Research output: Contribution to journalArticle

  14. Structural mechanisms of voltage sensing in G protein coupled receptors

    Vickery, O. N., Machtens, J-P., Tamburrino, G., Seeliger, D. & Zachariae, U. 7 Jun 2016 In : Structure. 24, 6, p. 997-1007 11 p.

    Research output: Contribution to journalArticle

  15. Combined changes in Wnt signalling response and contact inhibition induce altered proliferation in radiation treated intestinal crypts

    Dunn, S. J., Osborne, J., Appleton, P. L. & Näthke, I. 1 Jun 2016 In : Molecular Biology of the Cell. 27, 11, p. 1863-1874 12 p.

    Research output: Contribution to journalArticle

  16. Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes

    Hügle, M., Lucas, X., Weitzel, G., Ostrovskyi, D., Breit, B., Gerhardt, S., Schmidtkunz, K., Jung, M., Schüle, R., Einsle, O., Günther, S. & Wohlwend, D. 1 Jun 2016 In : Data in Brief. 7, p. 1370-1374 5 p.

    Research output: Contribution to journalArticle

  17. Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation

    Wu, G., Hitchen, P. G., Panico, M., North, S. J., Barbouche, M-R., Binet, D., Morris, H. R., Dell, A. & Haslam, S. M. Jun 2016 In : Glycoconjugate Journal. 33, 3, p. 447-456 10 p.

    Research output: Contribution to journalArticle

  18. Ribozymes and the mechanisms that underlie RNA catalysis

    Wilson, T. J., Liu, Y. & Lilley, D. M. J. Jun 2016 In : Frontiers of Chemical Science and Engineering. 10, 2, p. 178-185 8 p.

    Research output: Contribution to journalArticle

  19. The Diffusible Signal Factor Family of Bacterial Cell-Cell Signals

    Dow, J. M., Naughton, L. M., Hollmann, B., An, S. Q. & Ryan, R. P. 23 May 2016 In : Israel Journal of Chemistry. 56, 5, p. 321-329 9 p.

    Research output: Contribution to journalArticle

  20. Erythematous nodes, urticarial rash and arthralgias in a large pedigree with NLRC4-related autoinflammatory disease, expansion of the phenotype

    Volker-Touw, C. M. L., de Koning, H. D., Giltay, J., de Kovel, C., van Kempen, T. S., Oberndorff, K., Boes, M., van Steensel, M. A. M., van Well, G. T. J., Blokx, W. A. M., Schalkwijk, J., Simon, A., Frenkel, J. & van Gijn, M. E. 20 May 2016 In : British Journal of Dermatology.

    Research output: Contribution to journalLetter

  21. Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD

    Watson, A., Lipina, C., McArdle, H. J., Taylor, P. M. & Hundal, H. May 2016 In : Cellular Signalling. 28, 5, p. 412-424

    Research output: Contribution to journalArticle

  22. The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids

    Hoxhaj, G., Caddye, E., Najafov, A., Houde, V. P., Johnson, C., Dissanayake, K., Toth, R., Campbell, D. G., Prescott, A. R. & MacKintosh, C. 22 Apr 2016 In : eLife. 5, p. 1-18 18 p., e12278

    Research output: Contribution to journalArticle

  23. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling

    Zhou, Z., Tang, A. T., Wong, W. Y., Bamezai, S., Goddard, L. M., Shenkar, R., Zhou, S., Yang, J., Wright, A. C., Foley, M., Arthur, J. S. C., Whitehead, K. J., Awad, I. A., Li, D. Y., Zheng, X. & Kahn, M. L. 7 Apr 2016 In : Nature. 532, 7597, p. 122-126 5 p., 17178

    Research output: Contribution to journalArticle

  24. Direct non transcriptional role of NF-Y in DNA replication

    Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C. 1 Apr 2016 In : Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

    Research output: Contribution to journalArticle

  25. The chromatin remodelling enzymes SNF2H and SNF2L position nucleosomes adjacent to CTCF and other transcription

    Wiechens, N., Singh, V., Gkikopoulos, T., Schofield, P., Rocha, S. & Owen-Hughes, T. 28 Mar 2016 In : PLoS Genetics.

    Research output: Contribution to journalArticle

  26. A Trapped Covalent Intermediate of a Glycoside Hydrolase on the Pathway to Transglycosylation. Insights from Experiments and Quantum Mechanics/Molecular Mechanics Simulations

    Raich, L., Borodkin, V., Fang, W., Castro-Lopez, J., van Aalten, D. M. F., Hurtado-Guerrero, R. & Rovira, C. 16 Mar 2016 In : Journal of the American Chemical Society. 138, 10, p. 3325-3332 8 p.

    Research output: Contribution to journalArticle

  27. Keratin 12 missense mutation induces the unfolded protein response and apoptosis in meesmann epithelial corneal dystrophy

    Allen, E. H. A., Courtney, D. G., Atkinson, S. D., Moore, J. E., Mairs, L., Poulsen, E. T., Schiroli, D., Maurizi, E., Cole, C., Hickerson, R. P., James, J., Murgatroyd, H., Smith, F. J. D., MacEwen, C., Enghild, J. J., Nesbit, M. A., Leslie Pedrioli, D. M., McLean, W. H. I. & Moore, C. B. T. 15 Mar 2016 In : Human Molecular Genetics. 25, 6, p. 1176-1191 16 p., ddw001

    Research output: Contribution to journalArticle

  28. CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription

    Aregger, M., Kaskar, A., Varshney, D., Fernandez-Sanchez, M. E., Inesta-Vaquera, F. A., Weidlich, S. & Cowling, V. H. 3 Mar 2016 In : Molecular Cell. 61, 5, p. 734-746 13 p.

    Research output: Contribution to journalArticle

  29. AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

    Ross, F. A., MacKintosh, C. & Hardie, D. G. 2 Mar 2016 In : FEBS Journal.

    Research output: Contribution to journalArticle

  30. Comparative transcriptomics and proteomics of three different aphid species identifies core and diverse effector sets

    Thorpe, P., Cock, P. J. A. & Bos, J. 2 Mar 2016 In : BMC Genomics. 17, 1, 172

    Research output: Contribution to journalArticle

  31. Metadata management for high content screening in OMERO

    Li, S. , Besson, S. , Blackburn, C. , Carroll, M. , Ferguson, R. K. , Flynn, H. , Gillen, K. , Leigh, R. , Lindner, D. , Linkert, M. , Moore, W. J. , Ramalingam, B. , Rozbicki, E. , Rustici, G. , Tarkowska, A. , Walczysko, P. , Williams, E. , Allan, C. , Burel, J. M. & 2 others Moore, J. & Swedlow, J. R. 1 Mar 2016 In : Methods. p. 27-32

    Research output: Contribution to journalArticle

  32. Goserelin, as an ovarian protector during (neo)adjuvant breast cancer chemotherapy, prevents long term altered bone turnover

    Wilson, C., Gossiel, F., Leonard, R., Anderson, R. A., Adamson, D. J. A., Thomas, G. & Coleman, R. E. Mar 2016 In : Journal of Bone Oncology. 5, 1, p. 43-49 7 p.

    Research output: Contribution to journalArticle

  33. How the oxygen tolerance of a [NiFe]-hydrogenase depends on quaternary structure

    Wulff, P., Thomas, C., Sargent, F. & Armstrong, F. A. Mar 2016 In : Journal of Biological Inorganic Chemistry. 21, 1, p. 121 134 p.

    Research output: Contribution to journalArticle

  34. 4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1)

    Hügle, M., Lucas, X., Weitzel, G., Ostrovskyi, D., Breit, B., Gerhardt, S., Einsle, O., Günther, S. & Wohlwend, D. 25 Feb 2016 In : Journal of Medicinal Chemistry. 59, 4, p. 1518-1530 13 p.

    Research output: Contribution to journalArticle

  35. New synthetic routes to Triazolo-benzodiazepine analogues: expanding the scope of the bump-and-hole approach for selective Bromo and Extra-Terminal (BET) bromodomain inhibition

    Baud, M. G. J., Lin-Shiao, E., Zengerle, M., Tallant, C. & Ciulli, A. 25 Feb 2016 In : Journal of Medicinal Chemistry. 59, 4, p. 1492-1500 9 p.

    Research output: Contribution to journalArticle

  36. O-GlcNAc transferase inhibitors: Current tools and future challenges

    Trapannone, R., Rafie, K. & Van Aalten, D. M. F. 15 Feb 2016 In : Biochemical Society Transactions. 44, 1, p. 88-93 6 p.

    Research output: Contribution to journalArticle

  37. Uranium bioprecipitation mediated by yeasts utilizing organic phosphorus substrates

    Liang, X., Csetenyi, L. & Gadd, G. M. 5 Feb 2016 In : Applied Microbiology and Biotechnology. 100, 11, p. 5141-5151 11 p.

    Research output: Contribution to journalArticle

  38. Biophysical characterization of laforin-carbohydrate interaction

    Dias, D. M., Furtado, J., Wasielewski, E., Cruz, R., Costello, B., Cole, L., Faria, T. Q., Baaske, P., Brito, R. M. M., Ciulli, A., Simões, I., Macedo-Ribeiro, S., Faro, C., Geraldes, C. F. G. C. & Castanheira, P. 1 Feb 2016 In : Biochemical Journal. 473, 3, p. 335-345 11 p.

    Research output: Contribution to journalArticle

  39. IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

    Trost, M. & 22 others Naujoks, J., Tabeling, C., Dill, B. D., Hoffmann, C., Brown, A. S., Kunze, M., Kempa, S., Peter, A., Mollenkopf, H. J., Dorhoi, A., Kershaw, O., Gruber, A. D., Sander, L. E., Witzenrath, M., Herold, S., Nerlich, A., Hocke, A. C., van Driel, I., Suttorp, N., Bedoui, S., Hilbi, H. & Opitz, B. 1 Feb 2016 In : PLoS Pathogens. 12, 2, 27 p., e1005408

    Research output: Contribution to journalArticle

  40. Hand dermatitis in construction workers: a lesson in genetic epidemiology

    Brown, S. J. Feb 2016 In : British Journal of Dermatology. 174, 2, p. 263-265 3 p.

    Research output: Contribution to journalArticle

  41. NF-κB and HIF crosstalk in immune responses

    D'Ignazio, L., Bandarra, D. & Rocha, S. Feb 2016 In : FEBS Journal. 283, 3, p. 413-424 12 p.

    Research output: Contribution to journalArticle

  42. Non-Invasive Intravital Imaging of siRNA-Mediated Mutant Keratin Gene Repression in Skin

    Hickerson, R. P., Speaker, T. J., Lara, M. F., González-González, E., Flores, M. A., Contag, C. H. & Kaspar, R. L. Feb 2016 In : Molecular Imaging and Biology. 18, 1, p. 34-42 9 p.

    Research output: Contribution to journalArticle

  43. A Phytophthora infestans RXLR effector targets plant PP1c isoforms that promote late blight disease

    Boevink, P. C., Wang, X., McLellan, H., He, Q., Naqvi, S., Armstrong, M. R., Zhang, W., Hein, I., Gilroy, E. M., Tian, Z. & Birch, P. R. J. 29 Jan 2016 In : Nature Communications. 7, 10311

    Research output: Contribution to journalArticle

  44. Phosphoproteomics reveals that Parkinson’s disease kinase LRRK2 regulates a subset of Rab GTPases

    Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S., Lorentzen, E., Duddy, G., Wilson, S., Baptista, M. A. S., Fiske, B. K., Fell, M. J., Morrow, J. A., Reith, A. D., Alessi, D. R. & Mann, M. 29 Jan 2016 In : eLife. 5, JANUARY2016, e12813

    Research output: Contribution to journalArticle

  45. The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

    Bailly, A., Perrin, A., Bou Malhab, L. J., Pion, E., Larance, M., Nagala, M., Smith, P., O'Donohue, M-F., Gleizes, P-E., Zomerdijk, J., Lamond, A. I. & Xirodimas, D. P. 28 Jan 2016 In : Oncogene. 35, 4, p. 415-426 12 p.

    Research output: Contribution to journalArticle

  46. Sialylation and immune surveillance of cancer by siglecs

    Crocker, P. R. & Mohan, B. 27 Jan 2016 Glycosignals in Cancer: Mechanisms of Malignant Phenotypes. p. 125-138 14 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  47. Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms

    Ross, F. A., Jensen, T. E. & Hardie, D. G. 15 Jan 2016 In : Biochemical Journal. 473, 2, p. 189-199 11 p.

    Research output: Contribution to journalArticle

  48. Discovery and profiling of small RNAs responsive to stress conditions in the plant pathogen Pectobacterium atrosepticum

    Kwenda, S., Gorshkov, V., Ramesh, A. M., Naidoo, S., Rubagotti, E., Birch, P. R. J. & Moleleki, L. N. 12 Jan 2016 In : BMC Genomics. 17, 1, 47

    Research output: Contribution to journalArticle

  49. A Generic Platform for Cellular Screening Against Ubiquitin Ligases

    Maculins, T., Carter, N., Dorval, T., Hudson, K., Nissink, J. W. M., Hay, R. T. & Alwan, H. 8 Jan 2016 In : Scientific Reports. 6, 18940

    Research output: Contribution to journalArticle

  50. PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53

    Wimmer, P., Berscheminski, J., Blanchette, P., Groitl, P., Branton, P. E., Hay, R. T., Dobner, T. & Schreiner, S. 7 Jan 2016 In : Oncogene. 35, p. 69-82 14 p.

    Research output: Contribution to journalArticle

  51. Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities

    Teresa Pinto, A., Laranjeiro Pinto, M., Patrícia Cardoso, A., Monteiro, C., Teixeira Pinto, M., Filipe Maia, A., Castro, P., Figueira, R., Monteiro, A., Marques, M., Mareel, M., Dos Santos, S. G., Seruca, R., Adolfo Barbosa, M., Rocha, S. & JoséOliveira, M. 6 Jan 2016 In : Scientific Reports. 6, 18765

    Research output: Contribution to journalArticle

  52. Optimization of inhibitors of Mycobacterium tuberculosis pantothenate synthetase based on group efficiency analysis

    Hung, A. W., Silvestre, H. L., Wen, S., George, G. P. C., Boland, J., Blundell, T. L., Ciulli, A. & Abell, C. 5 Jan 2016 In : ChemMedChem. 11, 1, p. 38-42

    Research output: Contribution to journalArticle

  53. StreptomeDB 2.0 - An extended resource of natural products produced by streptomycetes

    Klementz, D., Döring, K., Lucas, X., Telukunta, K. K., Erxleben, A., Deubel, D., Erber, A., Santillana, I., Thomas, O. S., Bechthold, A. & Günther, S. 4 Jan 2016 In : Nucleic Acids Research. 44, D1, p. D509-D514 6 p.

    Research output: Contribution to journalArticle

  54. Aim, Load, Fire: The Type VI Secretion System, a Bacterial Nanoweapon

    Cianfanelli, F. R., Monlezun, L. & Coulthurst, S. J. Jan 2016 In : Trends in Microbiology. 24, 1, p. 51-62 12 p.

    Research output: Contribution to journalArticle

  55. Bacterial signal transduction by cyclic di-GMP and other nucleotide second messengers

    Hengge, R., Gründling, A., Jenal, U., Ryan, R. & Yildiz, F. Jan 2016 In : Journal of Bacteriology. 198, 1, p. 15-26 12 p.

    Research output: Contribution to journalArticle

  56. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells

    Ortmann, B., Bensaddek, D., Carvalhal, S., Moser, S. C., Mudie, S., Griffis, E. R., Swedlow, J. R., Lamond, A. I. & Rocha, S. Jan 2016 In : Journal of Cell Science. 129, 1, p. 191-205 15 p.

    Research output: Contribution to journalArticle

  57. Endemic Mimosa species from Mexico prefer alphaproteobacterial rhizobial symbionts

    Bontemps, C., Rogel, M. A., Wiechmann, A., Mussabekova, A., Moody, S., Simon, M. F., Moulin, L., Elliott, G. N., Lacercat-Didier, L., Dasilva, C., Grether, R., Camargo-Ricalde, S. L., Chen, W., Sprent, J. I., Martínez-Romero, E., Young, J. P. W. & James, E. K. Jan 2016 In : New Phytologist. 209, 1, p. 319-333 15 p.

    Research output: Contribution to journalArticle

  58. Pluses and minuses of ammonium and nitrate uptake and assimilation by phytoplankton and implications for productivity and community composition, with emphasis on nitrogen-enriched conditions

    Glibert, P. M., Wilkerson, F. P., Dugdale, R. C., Raven, J. A., Dupont, C. L., Leavitt, P. R., Parker, A. E., Burkholder, J. M. & Kana, T. M. Jan 2016 In : Limnology and Oceanography. 61, 1, p. 165-197 33 p., 10203

    Research output: Contribution to journalArticle

  59. Secreted cyclic di-GMP induces stalk cell differentiation in the eukaryote Dictyostelium discoideum

    Chen, Z. H. & Schaap, P. Jan 2016 In : Journal of Bacteriology. 198, 1, p. 27-31 5 p.

    Research output: Contribution to journalArticle

  60. Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

    Heider, M. R., Gu, M., Duffy, C. M., Mirza, A. M., Marcotte, L. L., Walls, A. C., Farrall, N., Hakhverdyan, Z., Field, M. C., Rout, M. P., Frost, A. & Munson, M. Jan 2016 In : Nature Structural & Molecular Biology. 23, 1, p. 59-66 8 p.

    Research output: Contribution to journalArticle

  61. The cytotoxic T cell proteome and its shaping by the kinase mTOR

    Hukelmann, J. L., Anderson, K. E., Sinclair, L. V., Grzes, K. M., Brenes Murillo, A., Hawkins, P. T., Stephens, L. R., Lamond, A. I. & Cantrell, D. A. Jan 2016 In : Nature Immunology. 17, 1, p. 104-112 9 p.

    Research output: Contribution to journalArticle

  62. The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability

    Salifou, K., Ray, S., Verrier, L., Aguirrebengoa, M., Trouche, D., Panov, K. I. & Vandromme, M. Jan 2016 In : Nature Communications. 7, 10174

    Research output: Contribution to journalArticle

  63. The ins and outs of CO2

    Raven, J. A. & Beardall, J. Jan 2016 In : Journal of Experimental Botany. 67, 1, p. 1-13 13 p.

    Research output: Contribution to journalArticle

  64. Imaging functional nucleic acid delivery to skin

    Kaspar, R. L., Hickerson, R. P., González-González, E., Flores, M. A., Speaker, T. P., Rogers, F. A., Milstone, L. M. & Contag, C. H. 2016 RNA Imaging: methods and protocols. Medarova , Z. (ed.). New York: Springer , p. 1-24 24 p. (Methods in molecular biology; vol. 1372)

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  65. The state-of-the art in macromolecular crystallization: The IYCr series concludes

    Weiss, M. S., Hunter, W. N. & Einspahr, H. M. 2016 In : Acta Crystallographica Section F: Structural Biology Communications. 72, p. 1 1 p.

    Research output: Contribution to journalArticle

  66. The use of the Rx spin label in orientation measurement on proteins, by EPR

    Stevens, M. A., McKay, J. E., Robinson, J. L. S., El Mkami, H., Smith, G. M. & Norman, D. G. 2016 In : Physical Chemistry Chemical Physics. 18, 8, p. 5799-5806 8 p.

    Research output: Contribution to journalArticle

  67. Biology is simple

    Newman, T. 30 Dec 2015 In : Physical Biology. 12, 6, 063002

    Research output: Contribution to journalArticle

  68. Evidence for a functional O-linked N-acetylglucosamine (O-GlcNAc) system in the thermophilic bacterium Thermobaculum terrenum

    Ostrowski, A., Gundogdu, M., Ferenbach, A. T., Lebedev, A. A. & Van Aalten, D. M. F. 18 Dec 2015 In : Journal of Biological Chemistry. 290, 51, p. 30291-30305 15 p.

    Research output: Contribution to journalArticle

  69. Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

    Jones, D. C., Foth, B. J., Urbaniak, M. D., Patterson, S., Ong, H. B., Berriman, M. & Fairlamb, A. H. 18 Dec 2015 In : PLoS Neglected Tropical Diseases. 9, 12, e0004299

    Research output: Contribution to journalArticle

  70. Dual functionality of O-GlcNAc transferase is required for Drosophila development

    Mariappa, D., Zheng, X., Schimpl, M., Raimi, O., Ferenbach, A. T., Müller, H-A. J. & van Aalten, D. M. F. 16 Dec 2015 In : Open Biology. 5, 12, 10 p., 150234

    Research output: Contribution to journalArticle

  71. The Pratylenchus penetrans transcriptome as a source for the development of alternative control strategies: mining for putative genes involved in parasitism and evaluation of in planta RNAi

    Vieira, P., Eves-Van Den Akker, S., Verma, R., Wantoch, S., Eisenback, J. D. & Kamo, K. 14 Dec 2015 In : PLoS ONE. 10, 12, 25 p., 0144674

    Research output: Contribution to journalArticle

  72. Subverting toll-like receptor signaling by bacterial pathogens

    McGuire, V. A. & Arthur, J. S. C. 1 Dec 2015 In : Frontiers in Immunology. 6, DEC, 8 p., 607

    Research output: Contribution to journalArticle

  73. Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

    Riethmuller, C., McAleer, M. A., Koppes, S. A., Abdayem, R., Franz, J., Haftek, M., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Irvine, A. D. & Kezic, S. Dec 2015 In : Journal of Allergy and Clinical Immunology. 136, 6, p. 1573-1580.e2 10 p.

    Research output: Contribution to journalArticle

  74. Granville Sharp Pattison (1791.–1851.): Škotski anatom i kirurg sklon sukobima

    Dantoni, A. V., Loukas, M., Black, S. & Shane Tubbs, R. Dec 2015 In : AMHA: Acta Medico-Historica Adriatica. 13, 2, p. 405-414 10 p.

    Research output: Contribution to journalArticle

  75. Integration of an [FeFe]-hydrogenase into the anaerobic metabolism of Escherichia coli

    Kelly, C. L., Pinske, C., Murphy, B. J., Parkin, A., Armstrong, F., Palmer, T. & Sargent, F. Dec 2015 In : Biotechnology Reports. 8, p. 94-104 11 p.

    Research output: Contribution to journalArticle

  76. The Concise Guide to PHARMACOLOGY 2015/16: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Catterall, W. A., Cidlowski, J. A., Davenport, A. P., Fabbro, D., Fan, G., McGrath, J. C., Spedding, M. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5729-5743 15 p.

    Research output: Contribution to journalArticle

  77. Role of structural dynamics at the receptor G protein interface for signal transduction

    Rose, A. S., Zachariae, U., Grubmüller, H., Hofmann, K. P., Scheerer, P. & Hildebrand, P. W. 25 Nov 2015 In : PLoS ONE. 10, 11, 13 p., e0143399

    Research output: Contribution to journalArticle

  78. GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD)

    van der Beek, S. L., Le Breton, Y., Ferenbach, A. T., Chapman, R. N., van Aalten, D. M. F., Navratilova, I., Boons, G. J., Mciver, K. S., van Sorge, N. M. & Dorfmueller, H. C. 24 Nov 2015 In : Molecular Microbiology. 98, 5, p. 946-962 16 p.

    Research output: Contribution to journalArticle

  79. Correction: Modulation of the surface proteome through multiple ubiquitylation pathways in African Trypanosomes

    Zoltner, M., Leung, K. F., Alsford, S., Horn, D. & Field, M. C. 23 Nov 2015 In : PLoS Pathogens. 11, 11, 3 p., e1005291

    Research output: Contribution to journalArticle

  80. The evolution of aggregative multicellularity and cell-cell communication in the Dictyostelia

    Du, Q., Kawabe, Y., Schilde, C., Chen, Z. & Schaap, P. 20 Nov 2015 In : Journal of Molecular Biology. 427, 23, p. 3722-3733 12 p.

    Research output: Contribution to journalArticle

  81. MTOR, PIK3C3, and autophagy: Signaling the beginning from the end

    Munson, M. J. & Ganley, I. G. 13 Nov 2015 In : Autophagy. 11, 12, p. 2375-2376 2 p.

    Research output: Contribution to journalArticle

  82. Land use and soil factors affecting accumulation of phosphorus species in temperate soils

    Stutter, M. I., Shand, C. A., George, T. S., Blackwell, M. S. A., Dixon, L., Bol, R., MacKay, R. L., Richardson, A. E., Condron, L. M. & Haygarth, P. M. 1 Nov 2015 In : Geoderma. 257-258, p. 29-39 11 p.

    Research output: Contribution to journalArticle

  83. Development of small-molecule Trypanosoma brucei N-myristoyltransferase inhibitors: discovery and optimisation of a novel binding mode

    Spinks, D., Smith, V., Thompson, S., Robinson, D. A., Luksch, T., Smith, A., Torrie, L. S., McElroy, S., Stojanovski, L., Norval, S., Collie, I. T., Hallyburton, I., Rao, B., Brand, S., Brenk, R., Frearson, J. A., Read, K. D., Wyatt, P. G. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1821-1836 16 p.

    Research output: Contribution to journalArticle

  84. Discovery of inhibitors of Trypanosoma brucei by phenotypic screening of a focused protein kinase library

    Woodland, A., Thompson, S., Cleghorn, L. A. T., Norcross, N., De Rycker, M., Grimaldi, R., Hallyburton, I., Rao, B., Norval, S., Stojanovski, L., Brun, R., Kaiser, M., Frearson, J. A., Gray, D. W., Wyatt, P. G., Read, K. D. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1809-1820 12 p.

    Research output: Contribution to journalArticle

  85. Growth rate hypothesis and efficiency of protein synthesis under different sulphate concentrations in two green algae

    Giordano, M., Palmucci, M. & Raven, J. A. Nov 2015 In : Plant, Cell & Environment. 38, 11, p. 2313-2317 5 p.

    Research output: Contribution to journalArticle

  86. Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

    McAleer, M. A., Pohler, E., Smith, F. J. D., Wilson, N. J., Cole, C., MacGowan, S., Koetsier, J. L., Godsel, L. M., Harmon, R. M., Gruber, R., Crumrine, D., Elias, P. M., McDermott, M., Butler, K., Broderick, A., Sarig, O., Sprecher, E., Green, K. J., McLean, W. H. I. & Irvine, A. D. Nov 2015 In : Journal of Allergy and Clinical Immunology. 136, 5, p. 1268-1276 9 p.

    Research output: Contribution to journalArticle

  87. The bacterial hydrophobin BslA is a switchable ellipsoidal Janus nanocolloid

    Brandani, G. B., Schor, M., Morris, R., Stanley-Wall, N., MacPhee, C. E., Marenduzzo, D. & Zachariae, U. 27 Oct 2015 In : Langmuir. 31, 42, p. 11558-11563 6 p.

    Research output: Contribution to journalArticle

  88. Modulation of the surface proteome through multiple ubiquitylation pathways in African Trypanosomes

    Zoltner, M., Leung, K. F., Alsford, S., Horn, D. & Field, M. C. 22 Oct 2015 In : PLoS Pathogens. 11, 10, 26 p., e1005236

    Research output: Contribution to journalArticle

  89. Discovery and optimisation studies of antimalarial phenotypic hits

    Mital, A., Murugesan, D., Kaiser, M., Yeates, C. & Gilbert, I. H. 20 Oct 2015 In : European Journal of Medicinal Chemistry. 103, p. 530-538 9 p.

    Research output: Contribution to journalArticle

  90. A transcriptional reference map of defence hormone responses in potato

    Wiesel, L., Davis, J. L., Milne, L., Redondo Fernandez, V., Herold, M. B., Middlefell Williams, J., Morris, J., Hedley, P. E., Harrower, B., Newton, A. C., Birch, P. R. J., Gilroy, E. M. & Hein, I. 19 Oct 2015 In : Scientific Reports. 5, 12 p., 15229

    Research output: Contribution to journalArticle

  91. Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations

    Mercier, S. , Küry, S. , Salort-Campana, E. , Magot, A. , Agbim, U. , Besnard, T. , Bodak, N. , Bou-Hanna, C. , Bréhéret, F. , Brunelle, P. , Caillon, F. , Chabrol, B. , Cormier-Daire, V. , David, A. , Eymard, B. , Faivre, L. , Figarella-Branger, D. , Fleurence, E. , Ganapathi, M. & 35 others Gherardi, R., Goldenberg, A., Hamel, A., Igual, J., Irvine, A. D., Israël-Biet, D., Kannengiesser, C., Laboisse, C., Le Caignec, C., Mahé, J. Y., Mallet, S., MacGowan, S., McAleer, M. A., McLean, I., Méni, C., Munnich, A., Mussini, J. M., Nagy, P. L., Odel, J., O'Regan, G. M., Péréon, Y., Perrier, J., Piard, J., Puzenat, E., Sampson, J. B., Smith, F., Soufir, N., Tanji, K., Thauvin, C., Ulane, C., Watson, R. M., Khumalo, N. P., Mayosi, B. M., Barbarot, S. & Bézieau, S. 15 Oct 2015 In : Orphanet Journal of Rare Diseases. 10, 16 p., 135

    Research output: Contribution to journalArticle

  92. Drosophila E-cadherin is required for the maintenance of ring canals anchoring to mechanically withstand tissue growth

    Loyer, N., Kolotuev, I., Pinot, M. & Borgne, R. L. 13 Oct 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 41, p. 12717-12722 6 p.

    Research output: Contribution to journalArticle

  93. Discovery of indoline-2-carboxamide derivatives as a new class of brain-penetrant inhibitors of Trypanosoma brucei

    Cleghorn, L. A. T., Albrecht, S., Stojanovski, L., Simeons, F. R. J., Norval, S., Kime, R., Collie, I. T., De Rycker, M., Campbell, L., Hallyburton, I., Frearson, J. A., Wyatt, P. G., Read, K. D. & Gilbert, I. H. 8 Oct 2015 In : Journal of Medicinal Chemistry. 58, 19, p. 7695-7706 12 p.

    Research output: Contribution to journalArticle

  94. BACE1 activity impairs neuronal glucose oxidation: rescue by beta-hydroxybutyrate and lipoic acid

    Findlay, J. A., Hamilton, D. L. & Ashford, M. L. 1 Oct 2015 In : Frontiers in Cellular Neuroscience. 9, 14 p., 382

    Research output: Contribution to journalArticle

  95. The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation

    Carvalhal, S., Abreu Ribeiro, S., Arocena, M., Kasciukovic, T., Temme, A., Koehler, K., Huebner, A. & Griffis, E. R. 1 Oct 2015 In : Molecular Biology of the Cell. 26, 19, p. 3424-3438 15 p.

    Research output: Contribution to journalArticle

  96. Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis

    Damerow, S., Hoppe, C., Bandini, G., Zarnovican, P., Buettner, F. F. R., Ferguson, M. A. J. & Routier, F. H. Oct 2015 In : International Journal for Parasitology. 45, 12, p. 783-790 8 p.

    Research output: Contribution to journalArticle

  97. AtRTD - a comprehensive reference transcript dataset resource for accurate quantification of transcript - specific expression in Arabidopsis thaliana

    Zhang, R., Calixto, C. P. G., Tzioutziou, N. A., James, A. B., Simpson, C. G., Guo, W., Marquez, Y., Kalyna, M., Patro, R., Eyras, E., Barta, A., Nimmo, H. G. & Brown, J. W. S. Oct 2015 In : New Phytologist. 208, 1, p. 96-101 6 p.

    Research output: Contribution to journalArticle

  98. DNA entropy reveals a significant difference in complexity between housekeeping and tissue specific gene promoters

    Thomas, D., Finan, C., Newport, M. J. & Jones, S. Oct 2015 In : Computational Biology and Chemistry. 58, p. 19-24 6 p.

    Research output: Contribution to journalArticle

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