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  1. DNA entropy reveals a significant difference in complexity between housekeeping and tissue specific gene promoters

    Thomas, D., Finan, C., Newport, M. J. & Jones, S. Oct 2015 In : Computational Biology and Chemistry. 58, p. 19-24 6 p.

    Research output: Contribution to journalArticle

  2. NEU3 sialidase as a marker of insulin sensitivity: Regulation by fatty acids

    Lipina, C., Nardi, F., Grace, H. & Hundal, H. S. 1 Sep 2015 In : Cellular Signalling. 27, 9, p. 1742-1750 9 p.

    Research output: Contribution to journalArticle

  3. A proposed harmonized LPS molecular-subtyping scheme for Cronobacter species

    Yan, Q., Jarvis, K. G., Chase, H. R., Hébert, K., Trach, L. H., Lee, C., Sadowski, J., Lee, B., Hwang, S., Sathyamoorthy, V., Mullane, N., Pava-Ripoll, M., Iversen, C., Pagotto, F., Fanning, S. & Tall, B. D. Sep 2015 In : Food Microbiology. 50, p. 38-43 6 p.

    Research output: Contribution to journalArticle

  4. The biocathode of microbial electrochemical systems and microbially-influenced corrosion

    Kim, B. H., Lim, S. S., Daud, W. R. W., Gadd, G. M. & Chang, I. S. Aug 2015 In : Bioresource Technology. 190, p. 395-401 7 p.

    Research output: Contribution to journalArticle

  5. Proteotoxic stress reprograms the chromatin landscape of SUMO modification

    Seifert, A., Schofield, P., Barton, G. & Hay, R. 7 Jul 2015 In : Science Signaling. 8, 384, p. rs7 14 p.

    Research output: Contribution to journalArticle

  6. Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

    Rog-Zielinska, E. A., Craig, M. A., Manning, J. R., Richardson, R. V., Gowans, G. J., Dunbar, D. R., Gharbi, K., Kenyon, C. J., Holmes, M. C., Hardie, D. G., Smith, G. L. & Chapman, K. E. 1 Jul 2015 In : Cell Death & Differentiation. 22, 7, p. 1106-1116 11 p.

    Research output: Contribution to journalArticle

  7. Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance

    McNeil, E. M., Astell, K. R., Ritchie, A. M., Shave, S., Houston, D. R., Bakrania, P., Jones, H. M., Khurana, P., Wallace, C., Chapman, T., Wear, M. A., Walkinshaw, M. D., Saxty, B. & Melton, D. W. 1 Jul 2015 In : DNA Repair. 31, p. 19-28 10 p.

    Research output: Contribution to journalArticle

  8. Maintenance of distinct melanocyte populations in the interfollicular epidermis

    Glover, J. D., Knolle, S., Wells, K. L., Liu, D., Jackson, I. J., Mort, R. L. & Headon, D. J. 1 Jul 2015 In : Pigment Cell and Melanoma Research. 28, 4, p. 476-480 5 p.

    Research output: Contribution to journalArticle

  9. AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle

    Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U. Jul 2015 In : Hypertension. 66, 1, p. 108-116 9 p.

    Research output: Contribution to journalArticle

  10. Global proteomics analysis of the response to starvation in C. elegans

    Larance, M., Pourkarimi, E., Wang, B., Brenes Murillo, A., Kent, R., Lamond, A. I. & Gartner, A. Jul 2015 In : Molecular & Cellular Proteomics. 14, 7, 26 p., MCP.2014.044289

    Research output: Contribution to journalArticle

  11. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. Jul 2015 In : Journal of Investigative Dermatology. 135, 7, p. 1919-1921 3 p.

    Research output: Contribution to journalLetter

  12. Surface flux patterns on planets in circumbinary systems and potential for photosynthesis

    Forgan, D. H., Mead, A., Cockell, C. S. & Raven, J. A. Jul 2015 In : International Journal of Astrobiology. 14, 3, p. 465-478 14 p.

    Research output: Contribution to journalArticle

  13. N-myristoyltransferase is a cell wall target in Aspergillus fumigatus

    Fang, W., Robinson, D. A., Raimi, O. G., Blair, D. E., Harrison, J. R., Lockhart, D. E. A., Torrie, L. S., Ruda, G. F., Wyatt, P. G., Gilbert, I. H. & van Aalten, D. M. F. 19 Jun 2015 In : ACS Chemical Biology. 10, 6, p. 1425-1434 10 p.

    Research output: Contribution to journalArticle

  14. Orthogonal thiol functionalization at a single atomic center for profiling transthiolation activity of E1 activating enzymes

    Stanley, M., Han, C., Knebel, A., Murphy, P., Shpiro, N. & Virdee, S. 19 Jun 2015 In : ACS Chemical Biology. 10, 6, p. 1542-1554 13 p.

    Research output: Contribution to journalArticle

  15. A novel multiple-stage antimalarial agent that inhibits protein synthesis

    Fairlamb, A. H. , Gilbert, I. H. & 61 others Baragana, B., Hallyburton, I., Lee, M. C. S., Norcross, N. R., Grimaldi, R., Otto, T. D., Proto, W. R., Blagborough, A. M., Meister, S., Wirjanata, G., Ruecker, A., Upton, L. M., Abraham, T. S., Almeida, M. J., Pradhan, A., Porzelle, A., Santos Martinez, M., Bolscher, J. M., Woodland, A., Norval, S., Zuccotto, F., Thomas, J., Simeons, F., Stojanovski, L., Osuna-Cabello, M., Brock, P. M., Churcher, T. S., Sala, K. A., Zakutansky, S. E., Belén Jiménez-Díaz, M., Maria Sanz, L., Riley, J., Basak, R., Campbell, M., Avery, V. M., Sauerwein, R. W., Dechering, K. J., Noviyanti, R., Campo, B., Frearson, J. A., Angulo-Barturen, I., Ferrer-Bazaga, S., Javier Gamo, F., Wyatt, P. G., Leroy, D., Siegl, P., Delves, M. J., Kyle, D. E., Wittlin, S., Marfurt, J., Price, R. N., Sinden, R. E., Winzeler, E. A., Charman, S. A., Bebrevska, L., Gray, D. W., Campbell, S., Willis, P. A., Rayner, J. C., Fidock, D. A. & Read, K. D. 18 Jun 2015 In : Nature. 522, 7556, p. 315-320 6 p.

    Research output: Contribution to journalArticle

  16. A link between ATP and SUR2A: a novel mechanism explaining cardioprotection at high altitude

    Mohammed Abdul, K. S., Jovanovic, S., Du, Q., Sukhodub, A. & Jovanovic, A. 15 Jun 2015 In : International Journal of Cardiology. 189, p. 73-76 4 p.

    Research output: Contribution to journalLetter

  17. GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ

    Li, Z., Wang, Y., Newton, I. P., Zhang, L., Ji, P. & Li, Z. Jun 2015 In : Cellular Signalling. 27, 6, p. 1237-1245 9 p.

    Research output: Contribution to journalArticle

  18. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    Knatko, E. V., Ibbotson, S. H., Zhang, Y., Higgins, M., Fahey, J. W., Talalay, P., Dawe, R. S., Ferguson, J., Huang, J. T-J., Clarke, R., Zheng, S., Saito, A., Kalra, S., Benedict, A. L., Honda, T., Proby, C. M. & Dinkova-Kostova, A. T. Jun 2015 In : Cancer Prevention Research. 8, 6, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  19. Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock in mice

    Yue, M., Hinkle, K., Davies, P., Trushina, E., Fiesel, F., Christenson, T., Schroeder, A., Zhang, L., Bowles, E., Behrouz, B., Lincoln, S., Beevers, J., Milnerwood, A., Kurti, A., McLean, P. J., Fryer, J. D., Springer, W., Dickson, D., Farrer, M. & Melrose, H. Jun 2015 In : Neurobiology of Disease. 78, p. 172-195 24 p.

    Research output: Contribution to journalArticle

  20. Transformation of vanadinite (Pb5 (VO4 )3 Cl) by fungi

    Ceci, A., Rhee, Y. J., Kierans, M., Hillier, S., Pendlowski, H., Gray, N., Persiani, A. M. & Gadd, G. M. Jun 2015 In : Environmental Microbiology. 17, 6, p. 2018-2034 17 p.

    Research output: Contribution to journalArticle

  21. U-box E3 ubiquitin ligase PUB17 acts in the nucleus to promote specific immune pathways triggered by Phytophthora infestans

    He, Q., McLellan, H., Boevink, P. C., Sadanandom, A., Xie, C., Birch, P. R. J. & Tian, Z. Jun 2015 In : Journal of Experimental Botany. 66, 11, p. 3189-3199 11 p.

    Research output: Contribution to journalArticle

  22. Uranium phosphate biomineralization by fungi

    Liang, X., Hillier, S., Pendlowski, H., Gray, N., Ceci, A. & Gadd, G. M. Jun 2015 In : Environmental Microbiology. 17, 6, p. 2064-2075 12 p.

    Research output: Contribution to journalArticle

  23. Application of RNAi to genomic drug target validation in schistosomes

    Guidi, A., Mansour, N. R., Paveley, R. A., Carruthers, I. M., Besnard, J., Hopkins, A. L., Gilbert, I. H. & Bickle, Q. D. 20 May 2015 In : PLoS Neglected Tropical Diseases. 9, 5, 22 p., e0003801

    Research output: Contribution to journalArticle

  24. Characterization of Arabidopsis transcriptional responses to different aphid species reveals genes that contribute to host susceptibility and non-host resistance

    Jaouannet, M., Morris, J. A., Hedley, P. E. & Bos, J. I. B. 20 May 2015 In : PLoS Pathogens. 11, 5, 26 p., e1004918

    Research output: Contribution to journalArticle

  25. Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

    Swamy, M., Abeler-Dörner, L., Chettle, J., Mahlakõiv, T., Goubau, D., Chakravarty, P., Ramsay, G., Reis e Sousa, C., Staeheli, P., Blacklaws, B. A., Heeney, J. L. & Hayday, A. C. 19 May 2015 In : Nature Communications. 6, 12 p., 7090

    Research output: Contribution to journalArticle

  26. Protein degradation and dynamic tRNA thiolation fine-tune translation at elevated temperatures

    Tyagi, K. & Pedrioli, P. G. A. 19 May 2015 In : Nucleic Acids Research. 43, 9, p. 4701-4712 12 p.

    Research output: Contribution to journalArticle

  27. Discovery of a pyrrolopyrimidine (JH-II-127), a highly potent, selective, and brain penetrant LRRK2 inhibitor

    Hatcher, J. M., Zhang, J., Choi, H. G., Ito, G., Alessi, D. R. & Gray, N. S. 14 May 2015 In : ACS Medicinal Chemistry Letters. 6, 5, p. 584-589 6 p.

    Research output: Contribution to journalArticle

  28. Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

    Wongpaiboonwattana, W. & Stavridis, M. P. 14 May 2015 In : JoVE: Journal of Visualized Experiments. 99, e52823

    Research output: Contribution to journalArticle

  29. Structural characterization of LRRK2 inhibitors

    Gilsbach, B. K., Messias, A. C., Ito, G., Sattler, M., Alessi, D. R., Wittinghofer, A. & Kortholt, A. 14 May 2015 In : Journal of Medicinal Chemistry. 58, 9, p. 3751-3756 6 p.

    Research output: Contribution to journalArticle

  30. Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells

    Pallett, L. J., Gill, U. S., Quaglia, A., Sinclair, L. V., Jover-Cobos, M., Schurich, A., Singh, K. P., Thomas, N., Das, A., Chen, A., Fusai, G., Bertoletti, A., Cantrell, D. A., Kennedy, P. T., Davies, N. A., Haniffa, M. & Maini, M. K. 11 May 2015 In : Nature Medicine. 21, 6, p. 591-600 10 p.

    Research output: Contribution to journalArticle

  31. The early metazoan Trichoplax adhaerens possesses a functional O-GlcNAc system

    Selvan, N., Mariappa, D., van den Toorn, H. W. P., Heck, A. J. R., Ferenbach, A. T. & van Aalten, D. M. F. 8 May 2015 In : Journal of Biological Chemistry. p. 11969-11982 14 p.

    Research output: Contribution to journalArticle

  32. Barley: a translational model for adaptation to climate change

    Dawson, I. K., Russell, J., Powell, W., Steffenson, B., Thomas, W. T. B. & Waugh, R. 1 May 2015 In : New Phytologist. 206, 3, p. 913-931 19 p.

    Research output: Contribution to journalArticle

  33. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

    Petherick, K. J., Conway, O. J. L., Mpamhanga, C., Osborne, S. A., Kamal, A., Saxty, B. & Ganley, I. G. 1 May 2015 In : Journal of Biological Chemistry. 290, 18, p. 11376-11383 8 p.

    Research output: Contribution to journalArticle

  34. Quantitative proteome analysis of temporally-resolved phagosomes following uptake via key phagocytic receptors

    Dill, B., Gierliński, M., Härtlova, A., González Arandilla, A., Guo, M., Clarke, R. G. & Trost, M. 1 May 2015 In : Molecular & Cellular Proteomics. 14, 5, p. 1334 1349 p., 16

    Research output: Contribution to journalArticle

  35. Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation

    Bulatov, E. & Ciulli, A. 1 May 2015 In : Biochemical Journal. 467, 3, p. 365-386 22 p.

    Research output: Contribution to journalArticle

  36. 84 The crystal structure and catalytic mechanism of the twister ribozyme

    Lilley, D. M. J., Liu, Y. & Wilson, T. J. May 2015 33 , Suppl 1, p. 54-55 2 p.

    Research output: Contribution to journalArticle

  37. Changes in the osmolarity of the embryonic microenvironment induce neural tube defects

    Jin, Y. M., Wang, G., Zhang, N., Wei, Y., Li, S., Chen, Y., Chuai, M., Lee, H. S. S., Hocher, B. & Yang, X. May 2015 In : Molecular Reproduction and Development. 82, 5, p. 365-376 12 p.

    Research output: Contribution to journalArticle

  38. Identification and structure solution of fragment hits against kinetoplastid N-myristoyltransferase

    Robinson, D. A. & Wyatt, P. G. May 2015 In : Acta Crystallographica Section F: Structural Biology Communications. 71, 5, p. 586-593 8 p.

    Research output: Contribution to journalArticle

  39. In search of future earths: assessing the possibility of finding Earth analogues in the later stages of their habitable lifetimes

    O'Malley-James, J. T., Greaves, J. S., Raven, J. A. & Cockell, C. S. May 2015 In : Astrobiology. 15, 5, p. 400-411 12 p.

    Research output: Contribution to journalArticle

  40. Macromolecular crystallography and what it can contribute to antiparasite drug discovery

    Hunter, W. N. & Weiss, M. S. May 2015 In : Acta Crystallographica Section F: Structural Biology Communications. 71, 5, p. 483-484 2 p.

    Research output: Contribution to journalEditorial

  41. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH

    Mohammed Abdul, K. S., Jovanović, S., Du, Q., Sukhodub, A. & Jovanović, A. May 2015 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1852, 5, p. 709-719 11 p.

    Research output: Contribution to journalArticle

  42. Multidimentional proteomics for cell biology

    Larance, M. & Lamond, A. I. May 2015 In : Nature Reviews Molecular Cell Biology. 16, 5, p. 269-280 12 p.

    Research output: Contribution to journalArticle

  43. Myc and mRNA capping

    Dunn, S. & Cowling, V. H. May 2015 In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1849, 5, p. 501-505 5 p.

    Research output: Contribution to journalArticle

  44. Optimising ketocarotenoid production in potato tubers: Effect of genetic background, transgene combinations and environment

    Campbell, R., Morris, W. L., Mortimer, C. L., Misawa, N., Ducreux, L. J. M., Morris, J. A., Hedley, P. E., Fraser, P. D. & Taylor, M. A. May 2015 In : Plant Science. 234, p. 27-37 11 p.

    Research output: Contribution to journalArticle

  45. The Top 10 oomycete pathogens in molecular plant pathology

    Kamoun, S. , Furzer, O. , Jones, J. D. G. , Judelson, H. S. , Ali, G. S. , Dalio, R. J. D. , Roy, S. G. , Schena, L. , Zambounis, A. , Panabières, F. , Cahill, D. , Ruocco, M. , Figueiredo, A. , Chen, X. R. , Hulvey, J. , Stam, R. , Lamour, K. , Gijzen, M. , Tyler, B. M. , Grünwald, N. J. & 14 others Mukhtar, M. S., Tomé, D. F. A., Tör, M., Van Den Ackerveken, G., McDowell, J., Daayf, F., Fry, W. E., Lindqvist-Kreuze, H., Meijer, H. J. G., Petre, B., Ristaino, J., Yoshida, K., Birch, P. R. J. & Govers, F. May 2015 In : Molecular Plant Pathology. 16, 4, p. 413-434 22 p.

    Research output: Contribution to journalArticle

  46. Development of a custom-designed, pan genomic DNA microarray to characterize strain-level diversity among Cronobacter spp.

    Tall, B. D. , Gangiredla, J. , Gopinath, G. R. , Yan, Q. , Chase, H. R. , Lee, B. , Hwang, S. , Trach, L. , Park, E. , Yoo, Y. , Chung, T. , Jackson, S. A. , Patel, I. R. , Sathyamoorthy, V. , Pava-Ripoll, M. , Kotewicz, M. L. , Carter, L. , Iversen, C. , Pagotto, F. , Stephan, R. & 3 others Lehner, A., Fanning, S. & Grim, C. J. 30 Apr 2015 In : Frontiers in Pediatrics. 3, 11 p., 36

    Research output: Contribution to journalArticle

  47. Editorial on plants as alternative hosts for human and animal pathogens

    Holden, N. J., Jackson, R. W. & Schikora, A. 30 Apr 2015 In : Frontiers in Microbiology. 6, 2 p., 397

    Research output: Contribution to journalEditorial

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