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College of Life Sciences

  1. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH

    Mohammed Abdul, K. S., Jovanović, S., Du, Q., Sukhodub, A. & Jovanović, A. May 2015 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1852, 5, p. 709-719 11 p.

    Research output: Contribution to journalArticle

  2. Phenolic compounds in blackcurrant (Ribes nigrum L.) leaves relative to leaf position and harvest date

    Vagiri, M., Conner, S., Stewart, D., Andersson, S. C., Verrall, S., Johansson, E. & Rumpunen, K. 1 Apr 2015 In : Food Chemistry. 172, p. 135-142 8 p.

    Research output: Contribution to journalArticle

  3. AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

    Hardie, D. G. Apr 2015 In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  4. Evaluation of in-situ magnetic signals from iron oxide nanoparticle-labeled PC12 cells by atomic force microscopy

    Wang, L., Min, Y., Wang, Z., Riggio, C., Calatayud, M. P., Pinkernelle, J., Raffa, V., Goya, G. F. ., Keilhoff, G. & Cuschieri, A. Mar 2015 In : Journal of Biomedical Nanotechnology. 11, 3, p. 457-468 12 p.

    Research output: Contribution to journalArticle

  5. Expression, purification and renaturation of truncated human integrin β1 from inclusion bodies of Escherichia coli

    Shi, T., Zhang, L., Li, Z., Newton, I. P. & Zhang, Q. Mar 2015 In : Protein Expression and Purification. 107, p. 13-19 7 p.

    Research output: Contribution to journalArticle

  6. Decreased adipogenesis and adipose tissue in mice with inactivated protein phosphatase 5

    Jacob, W., Rosenzweig, D., Vázquez-Martin, C., Duce, S. L. & Cohen, P. T. W. 15 Feb 2015 In : Biochemical Journal. 466, 1, p. 163-176 14 p.

    Research output: Contribution to journalArticle

  7. USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses

    Perez-Oliva, A. B., Lachaud, C., Szyniarowski, P., Muñoz, I., Macartney, T., Hickson, I., Rouse, J. & Alessi, D. R. 3 Feb 2015 In : EMBO Journal. 34, 3, p. 326-343 18 p.

    Research output: Contribution to journalArticle

  8. Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability

    Henderson, C. J., McLaughlin, L. A., Osuna-Cabello, M., Taylor, M., Gilbert, I., McLaren, A. W. & Wolf, C. R. 1 Feb 2015 In : Biochemical Journal. 465, 3, p. 479-488 10 p.

    Research output: Contribution to journalArticle

  9. Alignment of an acoustic manipulation device with cepstral analysis of electronic impedance data

    Hughes, D. A., Qiu, Y., Démoré, C., Weijer, C. J. & Cochran, S. Feb 2015 In : Ultrasonics. 56, p. 172-177 6 p.

    Research output: Contribution to journalArticle

  10. Evolutionary Relationships Among Barley and Arabidopsis Core Circadian Clock and Clock-Associated Genes

    Calixto, C. P. G., Waugh, R. & Brown, J. W. S. Feb 2015 In : Journal of Molecular Evolution. 80, 2, p. 108-119 12 p.

    Research output: Contribution to journalArticle

  11. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

    Pirkmajer, S., Kulkarni, S. S., Tom, R. Z., Ross, F. A., Hawley, S. A., Hardie, D. G., Zierath, J. R. & Chibalin, A. V. Feb 2015 In : Diabetes. 64, 2, p. 360-369 10 p.

    Research output: Contribution to journalArticle

  12. Mitogen and stress-activated kinases 1/2 regulate ischemia-induced hippocampal progenitor cell proliferation and neurogenesis

    Karelina, K., Liu, Y., Alzate-Correa, D., Wheaton, K. L., Hoyt, K. R., Arthur, J. S. C. & Obrietan, K. 29 Jan 2015 In : Neuroscience. 285, p. 292-302 11 p.

    Research output: Contribution to journalArticle

  13. RAB1A promotes Vaccinia virus replication by facilitating the production of intracellular enveloped virions

    Pechenick Jowers, T., Featherstone, R. J., Reynolds, D. K., Brown, H. K., James, J., Prescott, A., Haga, I. R. & Beard, P. M. 15 Jan 2015 In : Virology. 475, p. 66-73 8 p.

    Research output: Contribution to journalArticle

  14. Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells

    Ly, T., Endo, A. & Lamond, A. I. 2 Jan 2015 In : eLife. 2015, 4, 15 p.e04534

    Research output: Contribution to journalArticle

  15. Crystals on the cover 2015

    Einspahr, H., Weiss, M. S. & Hunter, W. N. Jan 2015 F71, 1, p. 1-2 2 p.

    Research output: Contribution to journalArticle

  16. Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes

    Glover, L., Alsford, S., Baker, N., Turner, D. J., Sanchez-Flores, A., Hutchinson, S., Hertz-Fowler, C., Berriman, M. & Horn, D. Jan 2015 In : Nature Protocols. 10, 1, p. 106-33 28 p.

    Research output: Contribution to journalArticle

  17. PTEN inhibitors: an evaluation of current compounds

    Spinelli, L., Lindsay, Y. E. & Leslie, N. R. Jan 2015 In : Advances in Biological Regulation. 57, p. 102-111 10 p.

    Research output: Contribution to journalArticle

  18. e dataset

    Rozbicki, E. 2015

    Research output: Non-textual formData set/Database

  19. Targeting Cyclic di-GMP signalling: a strategy to control biofilm formation?

    Caly, D. L., Bellini, D., Walsh, M. A., Dow, J. M. & Ryan, R. P. 2015 In : Current Pharmaceutical Design. 21, 1, p. 12-24 13 p.

    Research output: Contribution to journalArticle

  20. In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

    Hegde, V., Hickerson, R. P., Nainamalai, S., Campbell, P. A., Smith, F. J. D., McLean, W. H. I. & Leslie Pedrioli, D. M. 28 Dec 2014 In : Journal of Controlled Release: Official Journal of the Controlled Release Society, and of the Japan Society of Drug Delivery System. 196, p. 355-362 8 p.

    Research output: Contribution to journalArticle

  21. Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes

    Spinelli, L., Black, F. M., Berg, J. N., Eickholt, B. J. & Leslie, N. R. 19 Dec 2014 In : Journal of Medical Genetics.

    Research output: Contribution to journalArticle

  22. Managing patients on bisphosphonates: the practice of primary care dentists before and after the publication of national guidance

    Bonetti, D. L., Clarkson, J. E., Elouafkaoui, P., Stirling, D. A., Young, L. & Templeton, A. R. 19 Dec 2014 In : British Dental Journal. 217, 12, p. E25

    Research output: Contribution to journalArticle

  23. p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human nuclear exosome targeting complex

    Tiedje, C., Lubas, M., Tehrani, M., Menon, M. B., Ronkina, N., Rousseau, S., Cohen, P., Kotlyarov, A. & Gaestel, M. 18 Dec 2014 In : RNA: a Publication of the RNA Society.

    Research output: Contribution to journalArticle

  24. Stopped in its tracks: how λ-cyhalothrin can break the aphid transmission of a potato potyvirus

    Fenton, B., Salter, T., Malloch, G., Begg, G. & Anderson, E. 18 Dec 2014 In : Pest Management Science.

    Research output: Contribution to journalArticle

  25. The Dictyostelium prestalk inducer Differentiation Inducing Factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

    Sugden, C., Urbaniak, M. D., Araki, T. & Williams, J. G. 17 Dec 2014 In : Molecular Biology of the Cell.

    Research output: Contribution to journalArticle

  26. Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM

    Bone, R. A., Bailey, C. S. L., Wiedermann, G., Ferjentsik, Z., Appleton, P. L., Murray, P. J., Maroto, M. & Dale, J. K. 15 Dec 2014 In : Development. 141, 24, p. 4806-4816 11 p.

    Research output: Contribution to journalArticle

  27. Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2):ElonginBC:Cullin5:RING-box protein 2 (Rbx2)

    Bulatov, E., Martin, E. M., Chatterjee, S., Knebel, A., Shimamura, S., Konijnenberg, A., Johnson, C., Zinn, N., Grandi, P., Sobott, F. & Ciulli, A. 11 Dec 2014 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  28. A cyanobacterial light activated adenylyl cyclase partially restores development of a Dictyostelium discoideum, adenylyl cyclase a null mutant

    Chen, Z., Raffelberg, S., Losi, A., Schaap, P. & Gärtner, W. 10 Dec 2014 In : Journal of Biotechnology. 191, p. 246-249 4 p.

    Research output: Contribution to journalArticle

  29. Substrate recognition by the cell surface palmitoyl transferase DHHC5

    Howie, J., Reilly, L., Fraser, N. J., Vlachaki Walker, J., Wypijewski, . K. J., Ashford, M. L. J., Calaghan, S., McClafferty, H., Tian, L., Shipston, M. J., Boguslavskyi, A., Shattock, M. J. & Fuller, W. 9 Dec 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17534-17539 6 p.

    Research output: Contribution to journalArticle

  30. A holin and an endopeptidase are essential for chitinolytic protein secretion in Serratia marcescens

    Hamilton, J. J., Marlow, V. L., Owen, R. A., Costa, M. D. A. A., Guo, M., Buchanan, G., Chandra, G., Trost, M., Coulthurst, S. J., Palmer, T., Stanley-Wall, N. R. & Sargent, F. 8 Dec 2014 In : Journal of Cell Biology. 207, 5, p. 615-626 12 p.

    Research output: Contribution to journalArticle

  31. Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

    Pelisch, F., Sonneville, R., Pourkarimi, E., Agostinho, A., Blow, J. J., Gartner, A. & Hay, R. T. 5 Dec 2014 In : Nature Communications. 5, 12 p.5485

    Research output: Contribution to journalArticle

  32. Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans

    Masoudi, N., Ibanez-Cruceyra, P., Offenburger, S-L., Holmes, A. & Gartner, A. 4 Dec 2014 In : PLoS Genetics. 10, 12, 15 p.e1004767

    Research output: Contribution to journalArticle

  33. AMPK-Sensing Energy while Talking to Other Signaling Pathways

    Hardie, D. G. 2 Dec 2014 In : Cell Metabolism. 20, 6, p. 939-952 14 p.

    Research output: Contribution to journalArticle

  34. Evolutionary cell biology: Two origins, one objective

    Lynch, M., Field, M. C., Goodson, H. V., Malik, H. S., Pereira-Leal, J. B., Roos, D. S., Turkewitz, A. P. & Sazer, S. 2 Dec 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 48, p. 16990-16994 5 p.

    Research output: Contribution to journalArticle

  35. FMDV replicons encoding green fluorescent protein are replication competent

    Tulloch, F., Pathania, U., Luke, G. A., Nicholson, J., Stonehouse, N. J., Rowlands, D. J., Jackson, T., Tuthill, T., Haas, J., Lamond, A. I. & Ryan, M. D. 1 Dec 2014 In : Journal of Virological Methods. 209, p. 35-40 6 p.

    Research output: Contribution to journalArticle

  36. NQO2 is a reactive oxygen species generating off-target for acetaminophen

    Miettinen, T. P. & Björklund, M. 1 Dec 2014 In : Molecular Pharmaceutics. 11, 12, p. 4395-4404 10 p.

    Research output: Contribution to journalArticle

  37. AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

    Hardie, D. G. Dec 2014 In : Journal of Internal Medicine. 276, 6, p. 543-559 17 p.

    Research output: Contribution to journalArticle

  38. Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner

    Bremm, A., Moniz, S., Mader, J., Rocha, S. & Komander, D. Dec 2014 In : EMBO Reports. 15, 12, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  39. Disposition and Metabolic Profiling of [14C]Cerlapirdine Using Accelerator Mass Spectrometry

    Tse, S., Leung, L., Raje, S., Seymour, M., Shishikura, Y. & Obach, R. S. Dec 2014 In : Drug Metabolism and Disposition. 42, 12, p. 2023-2032 10 p.

    Research output: Contribution to journalArticle

  40. Erratum for De Rycker et al., Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

    De Rycker, M., Hallyburton, I., Thomas, J., Campbell, L., Wyllie, S., Joshi, D., Cameron, S., Gilbert, I. H., Wyatt, P. G., Frearson, J. A., Fairlamb, A. H. & Gray, D. W. Dec 2014 In : Antimicrobial Agents and Chemotherapy. 58, 12, p. 7622 1 p.

    Research output: Contribution to journalArticle

  41. Evaluation of the diagnostic accuracy of prototype rapid tests for human african trypanosomiasis

    Sternberg, J. M., Gierlinski, M., Biéler, S., Ferguson, M. A. J. & Ndung'u, J. M. Dec 2014 In : PLoS Neglected Tropical Diseases. 8, 12, p. e3373

    Research output: Contribution to journalArticle

  42. GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes

    Freeman, A. D. J., Liu, Y., Déclais, A-C., Gartner, A. & Lilley, D. M. J. Dec 2014 In : Journal of Molecular Biology. 426, 24, p. 3946-3959 14 p.

    Research output: Contribution to journalArticle

  43. Identification and characterization of MUS81 point mutations that abolish interaction with the SLX4 scaffold protein

    Nair, N., Castor, D., Macartney, T. & Rouse, J. Dec 2014 In : DNA Repair. 24, p. 131-137 7 p.

    Research output: Contribution to journalArticle

  44. Modelling multi-protein complexes using PELDOR distance measurements for rigid body minimisation experiments using XPLOR-NIH

    Hammond, C. M., Owen-Hughes, T. & Norman, D. G. Dec 2014 In : Methods (San Diego, Calif.). 70, 2-3, p. 139-153 15 p.

    Research output: Contribution to journalArticle

  45. Progress in understanding the mechanisms and functional importance of protein-membrane interactions in plants

    Hemsley, P. A. Dec 2014 In : New Phytologist. 204, 4, p. 741-743 3 p.

    Research output: Contribution to journalArticle

  46. Quantitative phosphoproteomics of cytotoxic T cells to reveal Protein Kinase D 2 regulated networks

    Navarro, M. N., Goebel, J., Hukelmann, J. L. & Cantrell, D. A. Dec 2014 In : Molecular & Cellular Proteomics. 13, 12, p. 3544-3557 14 p.

    Research output: Contribution to journalArticle

  47. The times they are a-changin' - news from Acta Crystallographica Section F

    Hunter, W. N. & Weiss, M. S. Dec 2014 In : Acta Crystallographica Section F: Structural Biology Communications. 70, 12, p. 1575 1 p.

    Research output: Contribution to journalEditorial

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