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  1. Discovery and profiling of small RNAs responsive to stress conditions in the plant pathogen Pectobacterium atrosepticum

    Kwenda, S., Gorshkov, V., Ramesh, A. M., Naidoo, S., Rubagotti, E., Birch, P. R. J. & Moleleki, L. N. 12 Jan 2016 In : BMC Genomics. 17, 1, 47

    Research output: Contribution to journalArticle

  2. A Generic Platform for Cellular Screening Against Ubiquitin Ligases

    Maculins, T., Carter, N., Dorval, T., Hudson, K., Nissink, J. W. M., Hay, R. T. & Alwan, H. 8 Jan 2016 In : Scientific Reports. 6, 18940

    Research output: Contribution to journalArticle

  3. Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities

    Teresa Pinto, A., Laranjeiro Pinto, M., Patrícia Cardoso, A., Monteiro, C., Teixeira Pinto, M., Filipe Maia, A., Castro, P., Figueira, R., Monteiro, A., Marques, M., Mareel, M., Dos Santos, S. G., Seruca, R., Adolfo Barbosa, M., Rocha, S. & JoséOliveira, M. 6 Jan 2016 In : Scientific Reports. 6, 18765

    Research output: Contribution to journalArticle

  4. Bacterial signal transduction by cyclic di-GMP and other nucleotide second messengers

    Hengge, R., Gründling, A., Jenal, U., Ryan, R. & Yildiz, F. Jan 2016 In : Journal of Bacteriology. 198, 1, p. 15-26 12 p.

    Research output: Contribution to journalArticle

  5. Endemic Mimosa species from Mexico prefer alphaproteobacterial rhizobial symbionts

    Bontemps, C., Rogel, M. A., Wiechmann, A., Mussabekova, A., Moody, S., Simon, M. F., Moulin, L., Elliott, G. N., Lacercat-Didier, L., Dasilva, C., Grether, R., Camargo-Ricalde, S. L., Chen, W., Sprent, J. I., Martínez-Romero, E., Young, J. P. W. & James, E. K. Jan 2016 In : New Phytologist. 209, 1, p. 319-333 15 p.

    Research output: Contribution to journalArticle

  6. Pluses and minuses of ammonium and nitrate uptake and assimilation by phytoplankton and implications for productivity and community composition, with emphasis on nitrogen-enriched conditions

    Glibert, P. M., Wilkerson, F. P., Dugdale, R. C., Raven, J. A., Dupont, C. L., Leavitt, P. R., Parker, A. E., Burkholder, J. M. & Kana, T. M. Jan 2016 In : Limnology and Oceanography. 61, 1, p. 165-197 33 p., 10203

    Research output: Contribution to journalArticle

  7. Secreted cyclic di-GMP induces stalk cell differentiation in the eukaryote Dictyostelium discoideum

    Chen, Z. H. & Schaap, P. Jan 2016 In : Journal of Bacteriology. 198, 1, p. 27-31 5 p.

    Research output: Contribution to journalArticle

  8. Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

    Heider, M. R., Gu, M., Duffy, C. M., Mirza, A. M., Marcotte, L. L., Walls, A. C., Farrall, N., Hakhverdyan, Z., Field, M. C., Rout, M. P., Frost, A. & Munson, M. Jan 2016 In : Nature Structural & Molecular Biology. 23, 1, p. 59-66 8 p.

    Research output: Contribution to journalArticle

  9. The cytotoxic T cell proteome and its shaping by the kinase mTOR

    Hukelmann, J. L., Anderson, K. E., Sinclair, L. V., Grzes, K. M., Brenes Murillo, A., Hawkins, P. T., Stephens, L. R., Lamond, A. I. & Cantrell, D. A. Jan 2016 In : Nature Immunology. 17, 1, p. 104-112 9 p.

    Research output: Contribution to journalArticle

  10. The histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability

    Salifou, K., Ray, S., Verrier, L., Aguirrebengoa, M., Trouche, D., Panov, K. I. & Vandromme, M. Jan 2016 In : Nature Communications. 7, 10174

    Research output: Contribution to journalArticle

  11. The ins and outs of CO2

    Raven, J. A. & Beardall, J. Jan 2016 In : Journal of Experimental Botany. 67, 1, p. 1-13 13 p.

    Research output: Contribution to journalArticle

  12. The state-of-the art in macromolecular crystallization: The IYCr series concludes

    Weiss, M. S., Hunter, W. N. & Einspahr, H. M. 2016 In : Acta Crystallographica Section F: Structural Biology Communications. 72, p. 1 1 p.

    Research output: Contribution to journalArticle

  13. Biology is simple

    Newman, T. 30 Dec 2015 In : Physical Biology. 12, 6, 063002

    Research output: Contribution to journalArticle

  14. Evidence for a functional O-linked N-acetylglucosamine (O-GlcNAc) system in the thermophilic bacterium Thermobaculum terrenum

    Ostrowski, A., Gundogdu, M., Ferenbach, A. T., Lebedev, A. A. & Van Aalten, D. M. F. 18 Dec 2015 In : Journal of Biological Chemistry. 290, 51, p. 30291-30305 15 p.

    Research output: Contribution to journalArticle

  15. Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

    Jones, D. C., Foth, B. J., Urbaniak, M. D., Patterson, S., Ong, H. B., Berriman, M. & Fairlamb, A. H. 18 Dec 2015 In : PLoS Neglected Tropical Diseases. 9, 12, e0004299

    Research output: Contribution to journalArticle

  16. Subverting toll-like receptor signaling by bacterial pathogens

    McGuire, V. A. & Arthur, J. S. C. 1 Dec 2015 In : Frontiers in Immunology. 6, DEC, 8 p., 607

    Research output: Contribution to journalArticle

  17. Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

    Riethmuller, C., McAleer, M. A., Koppes, S. A., Abdayem, R., Franz, J., Haftek, M., Campbell, L. E., MacCallum, S. F., McLean, W. H. I., Irvine, A. D. & Kezic, S. Dec 2015 In : Journal of Allergy and Clinical Immunology. 136, 6, p. 1573-1580.e2 10 p.

    Research output: Contribution to journalArticle

  18. Integration of an [FeFe]-hydrogenase into the anaerobic metabolism of Escherichia coli

    Kelly, C. L., Pinske, C., Murphy, B. J., Parkin, A., Armstrong, F., Palmer, T. & Sargent, F. Dec 2015 In : Biotechnology Reports. 8, p. 94-104 11 p.

    Research output: Contribution to journalArticle

  19. The Concise Guide to PHARMACOLOGY 2015/16: Overview

    Alexander, S. P. H., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Southan, C., Buneman, O. P., Catterall, W. A., Cidlowski, J. A., Davenport, A. P., Fabbro, D., Fan, G., McGrath, J. C., Spedding, M. & Davies, J. A. Dec 2015 In : British Journal of Pharmacology. 172, 24, p. 5729-5743 15 p.

    Research output: Contribution to journalArticle

  20. Role of structural dynamics at the receptor G protein interface for signal transduction

    Rose, A. S., Zachariae, U., Grubmüller, H., Hofmann, K. P., Scheerer, P. & Hildebrand, P. W. 25 Nov 2015 In : PLoS ONE. 10, 11, 13 p., e0143399

    Research output: Contribution to journalArticle

  21. GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD)

    van der Beek, S. L., Le Breton, Y., Ferenbach, A. T., Chapman, R. N., van Aalten, D. M. F., Navratilova, I., Boons, G. J., Mciver, K. S., van Sorge, N. M. & Dorfmueller, H. C. 24 Nov 2015 In : Molecular Microbiology. 98, 5, p. 946-962 16 p.

    Research output: Contribution to journalArticle

  22. Correction: Modulation of the surface proteome through multiple ubiquitylation pathways in African Trypanosomes

    Zoltner, M., Leung, K. F., Alsford, S., Horn, D. & Field, M. C. 23 Nov 2015 In : PLoS Pathogens. 11, 11, 3 p., e1005291

    Research output: Contribution to journalArticle

  23. The evolution of aggregative multicellularity and cell-cell communication in the Dictyostelia

    Du, Q., Kawabe, Y., Schilde, C., Chen, Z. & Schaap, P. 20 Nov 2015 In : Journal of Molecular Biology. 427, 23, p. 3722-3733 12 p.

    Research output: Contribution to journalArticle

  24. Development of small-molecule Trypanosoma brucei N-myristoyltransferase inhibitors: discovery and optimisation of a novel binding mode

    Spinks, D., Smith, V., Thompson, S., Robinson, D. A., Luksch, T., Smith, A., Torrie, L. S., McElroy, S., Stojanovski, L., Norval, S., Collie, I. T., Hallyburton, I., Rao, B., Brand, S., Brenk, R., Frearson, J. A., Read, K. D., Wyatt, P. G. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1821-1836 16 p.

    Research output: Contribution to journalArticle

  25. Discovery of inhibitors of Trypanosoma brucei by phenotypic screening of a focused protein kinase library

    Woodland, A., Thompson, S., Cleghorn, L. A. T., Norcross, N., De Rycker, M., Grimaldi, R., Hallyburton, I., Rao, B., Norval, S., Stojanovski, L., Brun, R., Kaiser, M., Frearson, J. A., Gray, D. W., Wyatt, P. G., Read, K. D. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1809-1820 12 p.

    Research output: Contribution to journalArticle

  26. Growth rate hypothesis and efficiency of protein synthesis under different sulphate concentrations in two green algae

    Giordano, M., Palmucci, M. & Raven, J. A. Nov 2015 In : Plant, Cell & Environment. 38, 11, p. 2313-2317 5 p.

    Research output: Contribution to journalArticle

  27. Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin

    McAleer, M. A., Pohler, E., Smith, F. J. D., Wilson, N. J., Cole, C., MacGowan, S., Koetsier, J. L., Godsel, L. M., Harmon, R. M., Gruber, R., Crumrine, D., Elias, P. M., McDermott, M., Butler, K., Broderick, A., Sarig, O., Sprecher, E., Green, K. J., McLean, W. H. I. & Irvine, A. D. Nov 2015 In : Journal of Allergy and Clinical Immunology. 136, 5, p. 1268-1276 9 p.

    Research output: Contribution to journalArticle

  28. Modulation of the surface proteome through multiple ubiquitylation pathways in African Trypanosomes

    Zoltner, M., Leung, K. F., Alsford, S., Horn, D. & Field, M. C. 22 Oct 2015 In : PLoS Pathogens. 11, 10, 26 p., e1005236

    Research output: Contribution to journalArticle

  29. Discovery and optimisation studies of antimalarial phenotypic hits

    Mital, A., Murugesan, D., Kaiser, M., Yeates, C. & Gilbert, I. H. 20 Oct 2015 In : European Journal of Medicinal Chemistry. 103, p. 530-538 9 p.

    Research output: Contribution to journalArticle

  30. Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations

    Mercier, S. , Küry, S. , Salort-Campana, E. , Magot, A. , Agbim, U. , Besnard, T. , Bodak, N. , Bou-Hanna, C. , Bréhéret, F. , Brunelle, P. , Caillon, F. , Chabrol, B. , Cormier-Daire, V. , David, A. , Eymard, B. , Faivre, L. , Figarella-Branger, D. , Fleurence, E. , Ganapathi, M. , Gherardi, R. & 34 others Goldenberg, A., Hamel, A., Igual, J., Irvine, A. D., Israël-Biet, D., Kannengiesser, C., Laboisse, C., Le Caignec, C., Mahé, J. Y., Mallet, S., MacGowan, S., McAleer, M. A., McLean, I., Méni, C., Munnich, A., Mussini, J. M., Nagy, P. L., Odel, J., O'Regan, G. M., Péréon, Y., Perrier, J., Piard, J., Puzenat, E., Sampson, J. B., Smith, F., Soufir, N., Tanji, K., Thauvin, C., Ulane, C., Watson, R. M., Khumalo, N. P., Mayosi, B. M., Barbarot, S. & Bézieau, S. 15 Oct 2015 In : Orphanet Journal of Rare Diseases. 10, 135

    Research output: Contribution to journalArticle

  31. Drosophila E-cadherin is required for the maintenance of ring canals anchoring to mechanically withstand tissue growth

    Loyer, N., Kolotuev, I., Pinot, M. & Borgne, R. L. 13 Oct 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 41, p. 12717-12722 6 p.

    Research output: Contribution to journalArticle

  32. Discovery of indoline-2-carboxamide derivatives as a new class of brain-penetrant inhibitors of Trypanosoma brucei

    Cleghorn, L. A. T., Albrecht, S., Stojanovski, L., Simeons, F. R. J., Norval, S., Kime, R., Collie, I. T., De Rycker, M., Campbell, L., Hallyburton, I., Frearson, J. A., Wyatt, P. G., Read, K. D. & Gilbert, I. H. 8 Oct 2015 In : Journal of Medicinal Chemistry. 58, 19, p. 7695-7706 12 p.

    Research output: Contribution to journalArticle

  33. Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia

    Schumacher, F. R., Siew, K., Zhang, J., Johnson, C., Wood, N., Cleary, S. E., Al Maskari, R. S., Ferryman, J. T., Hardege, I., Yasmin, . N. V., Figg, N. L., Enchev, R., Knebel, A., O'Shaughnessy, K. M. & Kurz, T. 1 Oct 2015 In : Embo Molecular Medicine. 7, 10, p. 1285-1306 22 p.

    Research output: Contribution to journalArticle

  34. The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation

    Carvalhal, S., Abreu Ribeiro, S., Arocena, M., Kasciukovic, T., Temme, A., Koehler, K., Huebner, A. & Griffis, E. R. 1 Oct 2015 In : Molecular Biology of the Cell. 26, 19, p. 3424-3438 15 p.

    Research output: Contribution to journalArticle

  35. Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis

    Damerow, S., Hoppe, C., Bandini, G., Zarnovican, P., Buettner, F. F. R., Ferguson, M. A. J. & Routier, F. H. Oct 2015 In : International Journal for Parasitology. 45, 12, p. 783-790 8 p.

    Research output: Contribution to journalArticle

  36. AtRTD - a comprehensive reference transcript dataset resource for accurate quantification of transcript-specific expression in Arabidopsis thaliana

    Zhang, R., Calixto, C. P. G., Tzioutziou, N. A., James, A. B., Simpson, C. G., Guo, W., Marquez, Y., Kalyna, M., Patro, R., Eyras, E., Barta, A., Nimmo, H. G. & Brown, J. W. S. Oct 2015 In : New Phytologist. 208, 1, p. 96-101 6 p.

    Research output: Contribution to journalArticle

  37. DNA entropy reveals a significant difference in complexity between housekeeping and tissue specific gene promoters

    Thomas, D., Finan, C., Newport, M. J. & Jones, S. Oct 2015 In : Computational Biology and Chemistry. 58, p. 19-24 6 p.

    Research output: Contribution to journalArticle

  38. The TatC component of the twin-arginine protein translocase functions as an obligate oligomer

    Cléon, F., Habersetzer, J., Alcock, F., Kneuper, H., Stansfeld, P. J., Basit, H., Wallace, M. I., Berks, B. C. & Palmer, T. Oct 2015 In : Molecular Microbiology. 98, 1, p. 111-129 19 p.

    Research output: Contribution to journalArticle

  39. Visualization of the Serratia type VI secretion system reveals unprovoked attacks and dynamic assembly

    Gerc, A. J., Diepold, A., Trunk, K., Porter, M., Rickman, C., Armitage, J. P., Stanley-Wall, N. R. & Coulthurst, S. J. 29 Sep 2015 In : Cell Reports. 12, 12, p. 2131-2142 12 p.

    Research output: Contribution to journalArticle

  40. Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging

    Duce, S. L., Weir-McCall, J. R., Gandy, S. J., Matthew, S. Z., Cassidy, D. B., McCormick, L., Rauchhaus, P., Looker, H., Colhoun, H. M. & Houston, J. G. 18 Sep 2015 In : Cardiovascular Diabetology. 14, 11 p., 122

    Research output: Contribution to journalArticle

  41. To hit or not to hit, that is the question -genome-wide structure-based druggability predictions for pseudomonas aeruginosa proteins

    Sarkar, A. & Brenk, R. 11 Sep 2015 In : PLoS ONE. 10, 9, e0137279

    Research output: Contribution to journalArticle

  42. A host KH RNA-binding protein is a susceptibility factor targeted by an RXLR effector to promote late blight disease

    Wang, X., Boevink, P., McLellan, H., Armstrong, M., Bukharova, T., Qin, Z. & Birch, P. R. J. 7 Sep 2015 In : Molecular Plant. 8, 9, p. 1385-1395 11 p.

    Research output: Contribution to journalArticle

  43. Binding of SGTA to Rpn13 selectively modulates protein quality control

    Leznicki, P., Korac-Prlic, J., Kliza, K., Husnjak, K., Nyathi, Y., Dikic, I. & High, S. 1 Sep 2015 In : Journal of Cell Science. 128, 17, p. 3187-3196 10 p.

    Research output: Contribution to journalArticle

  44. Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes

    Hobley, L., Harkins, C., MacPhee, C. E. & Stanley-Wall, N. R. 1 Sep 2015 In : FEMS Microbiology Reviews. 39, 5, p. 649-669 21 p.

    Research output: Contribution to journalArticle

  45. GSK3-mediated raptor phosphorylation supports amino acid-dependent Q2 mTORC1-directed signalling

    Stretton, C., Hoffmann, T. M., Munson, M. J., Prescott, A., Taylor, P. M., Ganley, I. G. & Hundal, H. 1 Sep 2015 In : Biochemical Journal. 470, 2, p. 207-221

    Research output: Contribution to journalArticle

  46. NEU3 sialidase as a marker of insulin sensitivity: Regulation by fatty acids

    Lipina, C., Nardi, F., Grace, H. & Hundal, H. S. 1 Sep 2015 In : Cellular Signalling. 27, 9, p. 1742-1750 9 p.

    Research output: Contribution to journalArticle

  47. Screen for multi-SUMO-binding proteins reveals a multi-SIM-binding mechanism for recruitment of the transcriptional regulator ZMYM2 to chromatin

    Aguilar-Martinez, E., Chen, X., Webber, A., Mould, A. P., Seifert, A., Hay, R. T. & Sharrocks, A. D. 1 Sep 2015 In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. E4854-E4863 10 p.

    Research output: Contribution to journalArticle

  48. A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development

    Mariappa, D., Selvan, N., Borodkin, V. S., Alonso , J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F. Sep 2015 In : Biochemical Journal. 470, 2, p. 255-262 8 p.

    Research output: Contribution to journalArticle

  49. A proposed harmonized LPS molecular-subtyping scheme for Cronobacter species

    Yan, Q., Jarvis, K. G., Chase, H. R., Hébert, K., Trach, L. H., Lee, C., Sadowski, J., Lee, B., Hwang, S., Sathyamoorthy, V., Mullane, N., Pava-Ripoll, M., Iversen, C., Pagotto, F., Fanning, S. & Tall, B. D. Sep 2015 In : Food Microbiology. 50, p. 38-43 6 p.

    Research output: Contribution to journalArticle

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