Dermatology

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Palmer, C. N. A. , Irvine, A. D. , Terron-Kwiatkowski, A. , Zhao, Y. , Liao, H. , Lee, S. P. , Goudie, D. R. , Sandilands, A. , Campbell, L. E. , Smith, F. J. D. , O'Regan, G. M. , Watson, R. M. , Cecil, J. E. , Bale, S. J. , Compton, J. G. , DiGiovanna, J. J. , Fleckman, P. , Lewis-Jones, S. , Arseculeratne, G. , Sergeant, A. & 7 others Munro, C. S., El Houate, B., McElreavey, K., Halkjaer, L. B., Bisgaard, H., Mukhopadhyay, S. & McLean, W. H. I. Apr-2006 In : Nature Genetics. 38, 4, p. 441-446, 6 p.

Research output: Contribution to journal › Article

A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin

Mackay, F. S., Woods, J. A., Moseley, H., Ferguson, J., Dawson, A., Parsons, S. & Sadler, P. J. 2006 In : Chemistry: a European Journal. 12, 11, p. 3155-3161, 7 p.

Research output: Contribution to journal › Article

Clinical and research applications of photodynamic therapy in dermatology: experience of the Scottish PDT Centre

Moseley, H., Ibbotson, S., Woods, J., Brancaleon, L., Lesar, A., Goodman, C. & Ferguson, J. 2006 In : Lasers in Surgery and Medicine. 38, 5, p. 403-416, 14 p.

Research output: Contribution to journal › Article

Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris

Smith, F. J. D., Irvine, A. D., Terron-Kwiatkowski, A., Sandilands, A., Campbell, L. E., Zhao, Y., Liao, H., Evans, A. T., Goudie, D. R., Lewis-Jones, S., Arseculeratne, G., Munro, C. S., Sergeant, A., O'Regan, G., Bale, S. J., Compton, J. G., DiGiovanna, J. J., Presland, R. B., Fleckman, P. & McLean, W. H. I. 2006 In : Nature Genetics. 38, 3, p. 337-342, 6 p.

Research output: Contribution to journal › Article

Transplatin is cytotoxic when photoactivated: enhanced formation of DNA cross-links

Heringova, P., Woods, J., Mackay, F. S., Kasparkova, J., Sadler, P. J. & Brabec, V. 2006 In : Journal of Medicinal Chemistry. 49, 26, p. 7792-7798, 7 p.

Research output: Contribution to journal › Article

A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome

Cassidy, A., van Steensel, M. A. M., Steijlen, P. M., van Geel, M., van der Velden, J., Morley, S., Terrinoni, A., Melino, G., Candi, E. & McLean, I. Dec-2005 In : American Journal of Human Genetics. 77, 6, p. 909-917, 9 p.

Research output: Contribution to journal › Article

The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21(Waf1/Cip1)

Beattie, P. E., Finlan, L. E., Kernohan, N. M., Thomson, G., Hupp, T. R. & Ibbotson, S. H. May-2005 In : British Journal of Dermatology. 152, 5, p. 1001-1008, 8 p.

Research output: Contribution to journal › Article

Photoactivated platinum(IV) anticancer complexes

Mackay, F. S., Woods, J., Moseley, H. & Sadler, P. J. 2005 In : British Journal of Dermatology. 152, 4, p. 857-858, 2 p., L7

Research output: Contribution to journal › Meeting abstract

Pilot screening programme for small molecule activators of p53

Berkson, R. G., Hollick, J. J., Westwood, N. J., Woods, J. A., Lane, D. P. & Lain, S. 2005 In : International Journal of Cancer. 115, 5, p. 701-710, 10 p.

Research output: Contribution to journal › Article