Discovery - University of Dundee - Online Publications

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Division of Cancer Research

  1. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  2. A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels

    Fernandes, G., Dasai, N., Kozlova, N., Mojadadi, A., Gall, M., Drew, E., Barratt, E., Madamidola, O. A., Brown, S. G., Milne, A. M., Martins Da Silva, S. J., Whalley, K. M., Barratt, C. L. R. & Jovanovic, A. Feb 2016 In : Human Reproduction. 31, 2, p. 287-297 11 p.

    Research output: Contribution to journalArticle

  3. Can angiotensin-converting enzyme inhibitors reduce the incidence, severity, and duration of radiation proctitis?

    Alashkham, A., Paterson, C., Rauchhaus, P. & Nabi, G. Jan 2016 In : International Journal of Radiation Oncology Biology Physics. 94, 1, p. 93-101 9 p.

    Research output: Contribution to journalArticle

  4. Re: A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin

    Fraser, C. G., Rapi, S. & Rubeca, T. Jan 2016 In : Journal of the National Cancer Institute. 108, 1, 2 p., djv312

    Research output: Contribution to journalLetter

  5. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

    Huang, W. , Thomas, B. , Flynn, R. A. , Gavzy, S. J. , Wu, L. , Kim, S. V. , Hall, J. A. , Miraldi, E. R. , Ng, C. P. , Rigo, F. , Meadows, S. , Montoya, N. R. , Herrera, N. G. , Domingos, A. I. , Rastinejad, F. , Myers, R. M. , Fuller-Pace, F. V. , Bonneau, R. , Chang, H. Y. , Acuto, O. & 1 others Littman, D. R. 24 Dec 2015 In : Nature. 528, 7583, p. 517-522 6 p., 16193

    Research output: Contribution to journalArticle

  6. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

  7. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  8. Development of small-molecule Trypanosoma brucei N-myristoyltransferase inhibitors: discovery and optimisation of a novel binding mode

    Spinks, D., Smith, V., Thompson, S., Robinson, D. A., Luksch, T., Smith, A., Torrie, L. S., McElroy, S., Stojanovski, L., Norval, S., Collie, I. T., Hallyburton, I., Rao, B., Brand, S., Brenk, R., Frearson, J. A., Read, K. D., Wyatt, P. G. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1821-1836 16 p.

    Research output: Contribution to journalArticle

  9. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T. & Hayes, J. D. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 108-146 39 p.

    Research output: Contribution to journalArticle

  10. The emerging role of Nrf2 in mitochondrial function

    Dinkova-Kostova, A. T. & Abramov, A. Y. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 179-188 10 p.

    Research output: Contribution to journalArticle

  11. Trends in socio-economic inequalities in the Scottish diet: 2001-2009

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. Nov 2015 In : Public Health Nutrition. 18, 16, p. 2970-2980 11 p.

    Research output: Contribution to journalArticle

  12. Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

    Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Smith, A-D., Urquhart, G., Bielawski, J., Finnegan, M. & Petty, R. 22 Oct 2015 In : BMC Cancer. 15, 1, 14 p., 762

    Research output: Contribution to journalArticle

  13. Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma

    Dahle-Smith, Å., Stevenson, D., Massie, D., Murray, G. I., Dutton, S. J., Roberts, C., Ferry, D., Osborne, A., Clark, C., Petty, R. D. & Miedzybrodzka, Z. 17 Oct 2015 In : Molecular Cytogenetics. 8, 9 p., 78

    Research output: Contribution to journalArticle

  14. FLCN and AMPK confer resistance to hyperosmotic stress via remodeling of glycogen stores

    Possik, E., Ajisebutu, A., Manteghi, S., Gingras, M-C., Vijayaraghavan, T., Flamand, M., Coull, B., Schmeisser, K., Duchaine, T., van Steensel, M., Hall, D. H. & Pause, A. 6 Oct 2015 In : PLoS Genetics. 11, 10, 18 p., e1005520

    Research output: Contribution to journalArticle

  15. Mice lacking beta2-integrin function remain glucose tolerant in spite of insulin resistance, neutrophil infiltration and inflammation

    Meakin, P. J., Morrison, V. L., Sneddon, C. C., Savinko, T., Uotila, L., Jalicy, S. M., Gabriel, J. L., Kang, L., Ashford, M. L. J. & Fagerholm, S. C. 25 Sep 2015 In : PLoS ONE. 10, 9, 15 p., e0138872

    Research output: Contribution to journalArticle

  16. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

    Kostov, R. V., Knatko, E., McLaughlin, L., Henderson, C., Zheng, S., Huang, J. T-J., Honda, T. & Dinkova-Kostova, A. T. 25 Sep 2015 In : Biochemical and Biophysical Research Communications. 465, 3, p. 402-407 6 p.

    Research output: Contribution to journalArticle

  17. Lysyl hydroxylase 3 localizes to epidermal basement membrane and Is reduced in patients with Recessive Dystrophic Epidermolysis Bullosa

    Watt, S. A., Dayal, J. H. S., Wright, S., Riddle, M., Pourreyron, C., McMillan, J. R., Kimble, R. M., Prisco, M., Gartner, U., Warbrick, E., McLean, W. H. I., Leigh, I. M., McGrath, J. A., Salas-Alanis, J. C., Tolar, J. & South, A. P. 18 Sep 2015 In : PLoS ONE. 10, 9, 15 p., e0137639

    Research output: Contribution to journalArticle

  18. A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial

    Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S. 2 Sep 2015 In : Trials. 16, 12 p., 390

    Research output: Contribution to journalArticle

  19. Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes

    Hobley, L., Harkins, C., MacPhee, C. E. & Stanley-Wall, N. R. 1 Sep 2015 In : FEMS Microbiology Reviews. 39, 5, p. 649-669 21 p.

    Research output: Contribution to journalArticle

  20. Is photodynamic diagnostic flexible ureterorenoscopy suitable for a patient presenting with chronic actinic dermatitis?

    Valentine, R., Kata, S., Ibbotson, S., Nabi, G. & Moseley, H. Sep 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 5, p. 279-281 3 p.

    Research output: Contribution to journalLetter

  21. Novel CARD11 mutations in human cutaneous squamous cell carcinoma lead to aberrant NF-κB regulation

    Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Arron, S. T., McHugh, A. T., Xue, D. J., Dayal, J. H. S., Proby, C. M., Harwood, C. A., Leigh, I. M. & South, A. P. Sep 2015 In : American Journal of Pathology. 185, 9, p. 2354-2363 10 p.

    Research output: Contribution to journalArticle

  22. Total levels, localization patterns, and proportions of sperm exhibiting phospholipase C zeta are significantly correlated with fertilization rates after intracytoplasmic sperm injection

    Yelumalai, S., Yeste, M., Jones, C., Amdani, S. N., Kashir, J., Mounce, G., Martins Da Silva, S. J., Barratt, C. L., McVeigh, E. & Coward, K. Sep 2015 In : Fertility and Sterility. 104, 3, p. 561-568.e4 12 p.

    Research output: Contribution to journalArticle

  23. Synthesis of carbohydrate capped silicon nanoparticles and their reduced cytotoxicity, in vivo toxicity, and cellular uptake

    Ahire, J. H., Behray, M., Webster, C. A., Wang, Q., Sherwood, V., Saengkrit, N., Ruktanonchai, U., Woramongkolchai, N. & Chao, Y. 26 Aug 2015 In : Advanced Healthcare Materials. 4, 12, p. 1877-1886 10 p.

    Research output: Contribution to journalArticle

  24. The fanconi anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL

    Miles, J. A., Frost, M. G., Carroll, E., Rowe, M. L., Howard, M. J., Sidhu, A., Chaugule, V. K., Alpi, A. F. & Walden, H. 21 Aug 2015 In : Journal of Biological Chemistry. 290, 34, p. 20995-21006 12 p.

    Research output: Contribution to journalArticle

  25. Cezanne regulates E2F1-dependent HIF2α expression

    Moniz, S., Bandarra, D., Biddlestone, J., Campbell, K. J., Komander, D., Bremm, A. & Rocha, S. 15 Aug 2015 In : Journal of Cell Science. 128, 16, p. 3082-3093 12 p.

    Research output: Contribution to journalArticle

  26. Selective expression of the MAPK phosphatase Dusp9/MKP-4 in mouse plasmacytoid dendritic cells and regulation of IFNβ production1

    Niedzielska, M., Raffi, F. A. M., Tel, J., Muench, S., Jozefowski, K., Alati, N., Lahl, K., Mages, J., Billmeier, U., Schiemann, M., Appelt, U. K., Wirtz, S., Sparwasser, T., Hochrein, H., Figdor, C. G., Keyse, S. M. & Lang, R. 15 Aug 2015 In : Journal of Immunology. 195, 4, p. 1753-1762 10 p.

    Research output: Contribution to journalArticle

  27. The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression

    Zhang, Y., Li, S., Xiang, Y., Qiu, L., Zhao, H. & Hayes, J. D. 13 Aug 2015 In : Scientific Reports. 5, 30 p., 12983

    Research output: Contribution to journalArticle

  28. The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

    O'Connell, M. A. & Hayes, J. D. 3 Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 687-689 3 p.

    Research output: Contribution to journalArticle

  29. The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics

    Dinkova-Kostova, A. T., Baird, L., Holmström, K. M., Meyer, C. J. & Abramov, A. Y. 3 Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 602-610 9 p.

    Research output: Contribution to journalArticle

  30. Correlation between reversal of DNA methylation and clinical symptoms in psoriatic epidermis following narrow-band UVB phototherapy

    Gu, X., Nylander, E., Coates, P. J., Fahraeus, R. & Nylander, K. Aug 2015 In : Journal of Investigative Dermatology. 135, 8, p. 2077-2083 7 p.

    Research output: Contribution to journalArticle

  31. Identifying the unmet supportive care needs of men living with and beyond prostate cancer: A systematic review

    Paterson, C., Robertson, A., Smith, A. & Nabi, G. Aug 2015 In : European Journal of Oncology Nursing. 19, 4, p. 405-418 14 p.

    Research output: Contribution to journalArticle

  32. Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

    McMahon, M. , Hayes, J. D. & 19 others Agathanggelou, A., Weston, V. J., Perry, T., Davies, N. J., Skowronska, A., Payne, D. T., Fossey, J. S., Oldreive, C. E., Wei, W., Pratt, G., Parry, H., Oscier, D., Coles, S. J., Hole, P. S., Darley, R. L., Moss, P., Stewart, G., Taylor, A. M. R. & Stankovic, T. Aug 2015 In : Haematologica. 100, 8, p. 1076-1085 10 p.

    Research output: Contribution to journalArticle

  33. The psychological impact of a colorectal cancer diagnosis following a negative fecal occult blood test result

    Miles, A., McClements, P. L., Steele, R. J. C., Redeker, C., Sevdalis, N. & Wardle, J. 24 Jul 2015 In : Cancer Epidemiology, Biomarkers & Prevention. 24, 7, p. 1032-1038 7 p.

    Research output: Contribution to journalArticle

  34. Regulation of the p53 response and its relationship to cancer

    Meek, D. W. 23 Jul 2015 In : Biochemical Journal. 469, 3, p. 325-346 22 p.

    Research output: Contribution to journalArticle

  35. Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

    Rog-Zielinska, E. A., Craig, M. A., Manning, J. R., Richardson, R. V., Gowans, G. J., Dunbar, D. R., Gharbi, K., Kenyon, C. J., Holmes, M. C., Hardie, D. G., Smith, G. L. & Chapman, K. E. 1 Jul 2015 In : Cell Death & Differentiation. 22, 7, p. 1106-1116 11 p.

    Research output: Contribution to journalArticle

  36. New insights into the role of histone deacetylases as coactivators of inflammatory gene expression

    Schmitz, M. L. & de la Vega, L. 1 Jul 2015 In : Antioxidants & Redox Signaling. 23, 1, p. 85-98 14 p.

    Research output: Contribution to journalArticle

  37. Calculation of limits for significant bidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Jul 2015 In : Annals of Clinical Biochemistry. 52, 4, p. 434-440 7 p.

    Research output: Contribution to journalArticle

  38. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., Macleod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & on behalf of the BeWEL team Jul 2015 In : Colorectal Disease. 17, 7, p. 589-594 6 p.

    Research output: Contribution to journalArticle

  39. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. Jul 2015 In : Journal of Investigative Dermatology. 135, 7, p. 1919-1921 3 p.

    Research output: Contribution to journalLetter

  40. Motion estimation-based image enhancement in ultrasound imaging

    Morin, R., Basarab, A., Bidon, S. & Kouamé, D. Jul 2015 In : Ultrasonics. 60, p. 19-26 8 p.

    Research output: Contribution to journalArticle

  41. Prime mover or fellow traveller: 25-hydroxy vitamin D's seasonal variation, cardiovascular disease and death in the Scottish Heart Health Extended Cohort (SHHEC)

    Tunstall-Pedoe, H., Woodward, M., Hughes, M., Anderson, A., Kennedy, G., Belch, J., Kuulasmaa, K. & MORGAM Investigators 21 Jun 2015 In : International Journal of Epidemiology. 11 p.

    Research output: Contribution to journalArticle

  42. New monocyclic, bicyclic, and tricyclic ethynylcyanodienones as activators of the Keap1/Nrf2/ARE pathway and inhibitors of inducible nitric oxide synthase

    Li, W., Zheng, S., Higgins, M., Morra, R. P., Mendis, A. T., Chien, C-W., Ojima, I., Mierke, D. F., Dinkova-Kostova, A. T. & Honda, T. 11 Jun 2015 In : Journal of Medicinal Chemistry. 58, 11, p. 4738-4748 11 p.

    Research output: Contribution to journalArticle

  43. Corneal tissue interactions of a new 345 nm ultraviolet femtosecond laser

    Hammer, C. M., Petsch, C., Klenke, J., Skerl, K., Paulsen, F., Kruse, F. E., Seiler, T. & Menzel-Severing, J. Jun 2015 In : Journal of Cataract and Refractive Surgery. 41, 6, p. 1279-1288 10 p.

    Research output: Contribution to journalArticle

  44. Individual variability analysis of fluorescence parameters measured in skin with different levels of nutritive blood flow

    Dunaev, A. V., Dremin, V. V., Zherebtsov, E. A., Rafailov, I. E., Litvinova, K. S., Palmer, S. G., Stewart, N. A., Sokolovski, S. G. & Rafailov, E. U. Jun 2015 In : Medical Engineering & Physics. 37, 6, p. 574-583 10 p.

    Research output: Contribution to journalArticle

  45. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    Knatko, E. V., Ibbotson, S. H., Zhang, Y., Higgins, M., Fahey, J. W., Talalay, P., Dawe, R. S., Ferguson, J., Huang, J. T-J., Clarke, R., Zheng, S., Saito, A., Kalra, S., Benedict, A. L., Honda, T., Proby, C. M. & Dinkova-Kostova, A. T. Jun 2015 In : Cancer Prevention Research. 8, 6, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  46. Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

    McGarry, D. J., Chen, W., Chakravarty, P., Lamont, D. L., Wolf, C. R. & Henderson, C. J. Jun 2015 In : Biochemical Journal. 469, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  47. Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma

    Boldrup, L., Coates, P. J., Laurell, G., Wilms, T., Fahraeus, R. & Nylander, K. 26 May 2015 In : British Journal of Cancer. 112, 11, p. 1760-1765 6 p.

    Research output: Contribution to journalArticle

  48. MAGE-A cancer/testis antigens inhibit MDM2 ubiquitylation function and promote increased levels of MDM4

    Marcar, L., Ihrig, B., Hourihan, J., Bray, S. E., Quinlan, P. R., Jordan, L. B., Thompson, A. M., Hupp, T. R. & Meek, D. W. 22 May 2015 In : PLoS ONE. 10, 5, 19 p., e0127713

    Research output: Contribution to journalArticle

  49. Monte Carlo modelling of daylight activated photodynamic therapy

    Campbell, C. L., Wood, K., Valentine, R. M., Brown, C. T. A. & Moseley, H. 21 May 2015 In : Physics in Medicine and Biology. 60, 10, p. 4059-4073 15 p.

    Research output: Contribution to journalArticle

  50. Fc receptors in mucosal immunology

    van Egmond, M., Bakema, J. E. & Woof, J. M. 15 May 2015 Mucosal immunology: Fourth edition. Mestecky, J., Strober, W., Russell, M. W., Kelsall, B. L., Cheroutre, H. & Lambrecht, B. N. (eds.). 4th ed. London: Academic Press, Vol. 1, p. 409-428 20 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  51. Mucosal immunoglobulins

    Woof, J. M. & Mestecky, J. 15 May 2015 Mucosal Immunology: Fourth edition. Mestecky, J., Strober, W., Russell, M. W., Kelsall, B. L., Cheroutre, H. & Lambrecht, B. N. (eds.). 4th ed. London: Academic Press, Vol. 1, p. 287-324 38 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  52. Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

    Wongpaiboonwattana, W. & Stavridis, M. P. 14 May 2015 In : JoVE: Journal of Visualized Experiments. 99, e52823

    Research output: Contribution to journalArticle

  53. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

    Bell, K. F. S., Al-Mubarak, B., Martel, M. A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., Bilican, B., Chowdhry, S., Meakin, P. J., Ashford, M. L. J., Wyllie, D. J. A., Scannevin, R. H., Chandran, S., Hayes, J. D. & Hardingham, G. E. 13 May 2015 In : Nature Communications. 6, 15 p., 7066

    Research output: Contribution to journalArticle

  54. A quantitative assessment of ultraviolet radiation transmission through compression socks

    Valentine, R. & Moseley, H. May 2015 In : British Journal of Dermatology. 172, 5, p. 1445-1447 3 p.

    Research output: Contribution to journalLetter

  55. Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris)

    Moffat, C., Pacheco, J. G., Sharp, S., Samson, A. J., Bollan, K. A., Huang, J., Buckland, S. T. & Connolly, C. N. May 2015 In : FASEB Journal. 29, 5, p. 2112-2119 8 p.

    Research output: Contribution to journalArticle

  56. Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

    Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

    Research output: Contribution to journalArticle

  57. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

  58. Preliminary validation of thiel embalmed cadavers for laparoscopic radical nephrectomy

    Rai, B. P., Stolzenburg, J. U., Healy, S., Tang, B., Jones, P., Sweeney, C., Somani, B. K., Biyani, C. S. & Nabi, G. May 2015 In : Journal of Endourology. 29, 5, p. 595-603 9 p.

    Research output: Contribution to journalArticle

  59. Quantitative urinary proteomics using stable isotope labelling by peptide dimethylation in patients with prostate cancer

    Li, C., Zang, T., Wrobel, K., Huang, J. T. J. & Nabi, G. May 2015 In : Analytical and Bioanalytical Chemistry. 407, 12, p. 3393-3404 12 p.

    Research output: Contribution to journalArticle

  60. The 1999 Stockholm Consensus Conference on quality specifications in laboratory medicine

    Fraser, C. G. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 837-840 4 p.

    Research output: Contribution to journalArticle

  61. The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site

    Orzol, P., Holcakova, J., Nekulova, M., Nenutil, R., Vojtesek, B. & Coates, P. J. May 2015 In : Histology and Histopathology. 30, 5, p. 503-521 19 p.

    Research output: Contribution to journalArticle

  62. The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

    Woods, J. A., Evans, A., Forbes, P. D., Coates, P. J., Gardner, J., Valentine, R. M., Ibbotson, S. H., Ferguson, J., Fricker, C. & Moseley, H. May 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 3, p. 159-166 8 p.

    Research output: Contribution to journalArticle

  63. MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and-independent mechanisms

    Amankwatia, E. B., Chakravarty, P., Carey, F. A., Weidlich, S., Steele, R. J. C., Munro, A. J., Wolf, C. R. & Smith, G. 28 Apr 2015 In : British Journal of Cancer. 112, 9, p. 1480-1490 11 p.

    Research output: Contribution to journalArticle

  64. Choosing the best method to estimate the energy density of a population using food purchase data

    Wrieden, W. L., Armstrong, J., Anderson, A. S., Sherriff, A. & Barton, K. L. Apr 2015 In : Journal of Human Nutrition and Dietetics. 28, 2, p. 126-134 9 p.

    Research output: Contribution to journalArticle

  65. Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

    Henderson, C. J., McLaughlin, L. A., Scheer, N., Stanley, L. A. & Wolf, C. R. Apr 2015 In : Molecular Pharmacology. 87, 4, p. 733-739 7 p.

    Research output: Contribution to journalArticle

  66. Nrf2 regulates ROS production by mitochondria and NADPH oxidase

    Kovac, S., Angelova, P. R., Holmström, K. M., Zhang, Y., Dinkova-Kostova, A. T. & Abramov, A. Y. Apr 2015 In : Biochimica et Biophysica Acta: General Subjects. 1850, 4, p. 794-801 8 p.

    Research output: Contribution to journalArticle

  67. Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks

    McDermott, F. D., Heeney, A., Kelly, M. E., Steele, R. J., Carlson, G. L. & Winter, D. C. Apr 2015 In : British Journal of Surgery. 102, 5, p. 462-479 18 p.

    Research output: Contribution to journalArticle

  68. Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

    Fleming, S. & 44 others Kovac, M., Navas, C., Horswell, S., Salm, M., Bardella, C., Rowan, A., Stares, M., Castro-Giner, F., Fisher, R., de Bruin, E. C., Kovacova, M., Gorman, M., Makino, S., Williams, J., Jaeger, E., Jones, A., Howarth, K., Larkin, J., Pickering, L., Gore, M., Nicol, D. L., Hazell, S., Stamp, G., O'Brien, T., Challacombe, B., Matthews, N., Phillimore, B., Begum, S., Rabinowitz, A., Varela, I., Chandra, A., Horsfield, C., Polson, A., Tran, M., Bhatt, R., Terracciano, L., Eppenberger-Castori, S., Protheroe, A., Maher, E., El Bahrawy, M., Ratcliffe, P., Heinimann, K., Swanton, C. & Tomlinson, I. 19 Mar 2015 In : Nature Communications. 6, 11 p., 6336

    Research output: Contribution to journalArticle

  69. Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins

    Colin, D. J., Hain, K. O., Allan, L. A. & Clarke, P. R. 11 Mar 2015 In : Open Biology. 5, 13 p., 140156

    Research output: Contribution to journalArticle

  70. Detection of urinary bladder cancer cells using redox ratio and double excitation wavelengths autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 1 Mar 2015 In : Biomedical Optics Express. 6, 3, p. 977-986 10 p.

    Research output: Contribution to journalArticle

  71. An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes

    MacLeod, A. K., Fallon, P. G., Sharp, S., Henderson, C. J., Wolf, C. R. & Huang, J. T-J. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 750-760 11 p.

    Research output: Contribution to journalArticle

  72. Biological variation: a still evolving facet of laboratory medicine

    Simundic, A. M., Bartlett, W. A. & Fraser, C. G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 189-190 2 p.

    Research output: Contribution to journalEditorial

  73. Calculation of limits for significant unidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 237-244 8 p.

    Research output: Contribution to journalArticle

  74. Distal nephron neoplasms

    Fleming, S. Mar 2015 In : Seminars in Diagnostic Pathology. 32, 2, p. 114-123 10 p.

    Research output: Contribution to journalArticle

  75. Laser-induced autofluorescence spectroscopy: Can it be of importance in detection of bladder lesions?

    Aboumarzouk, O., Valentine, R., Buist, R., Ahmad, S., Nabi, G., Eljamel, S., Moseley, H. & Kata, S. G. Mar 2015 In : Photodiagnosis and Photodynamic Therapy. 12, 1, p. 76-83 8 p.

    Research output: Contribution to journalArticle

  76. Thiel Embalming Method for Cadaver Preservation: A Review of New Training Model for Urologic Skills Training

    Healy, S. E., Rai, B. P., Biyani, C. S., Eisma, R., Soames, R. W. & Nabi, G. Mar 2015 In : Urology. 85, 3, p. 499-504 6 p.

    Research output: Contribution to journalArticle

  77. Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability

    Henderson, C. J., McLaughlin, L. A., Osuna-Cabello, M., Taylor, M., Gilbert, I., McLaren, A. W. & Wolf, C. R. 1 Feb 2015 In : Biochemical Journal. 465, 3, p. 479-488 10 p.

    Research output: Contribution to journalArticle

  78. Detection and characterisation of biopsy tissue using quantitative optical coherence elastography (OCE) in men with suspected prostate cancer

    Li, C., Guan, G., Ling, Y., Hsu, Y-T., Song, S., Huang, J. T-J., Lang, S., Wang, R. K., Huang, Z. & Nabi, G. 1 Feb 2015 In : Cancer Letters. 357, 1, p. 121-128 8 p.

    Research output: Contribution to journalArticle

  79. Insight from the air-skin interface

    O'Shaughnessy, R. F. L. & Brown, S. J. Feb 2015 In : Journal of Investigative Dermatology. 135, 2, p. 331-333 3 p.

    Research output: Contribution to journalComment/debate

  80. Oxidation reduction is a key process for successful treatment of psoriasis by narrow-band UVB phototherapy

    Gu, X., Nylander, E., Coates, P. J. & Nylander, K. Feb 2015 In : Acta Dermato-Venereologica. 95, 2, p. 140-146 7 p.

    Research output: Contribution to journalArticle

  81. Terms and symbols used in studies on biological variation: the need for harmonization

    Simundic, A. M., Kackov, S., Miler, M., Fraser, C. G. & Petersen, P. H. Feb 2015 In : Clinical Chemistry. 61, 2, p. 438-439 2 p.

    Research output: Contribution to journalLetter

  82. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration

    Pajaud, J., Ribault, C., Ben Mosbah, I., Rauch, C., Henderson, C., Bellaud, P., Aninat, C., Loyer, P., Morel, F. & Corlu, A. 15 Jan 2015 In : Cell Death and Disease. 6, 13 p., e1598

    Research output: Contribution to journalArticle

  83. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

    Brown, S. J. & 38 others Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I., Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S. & Cordell, H. J. 8 Jan 2015 In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticle

  84. An updated Asia Pacific Consensus Recommendations on colorectal cancer screening

    Sung, J. J. Y., Ng, S. C., Chan, F. K. L., Chiu, H. M., Kim, H. S., Matsuda, T., Ng, S. S. M., Lau, J. Y. W., Zheng, S., Adler, S., Reddy, N., Yeoh, K. G., Tsoi, K. K. F., Ching, J. Y. L., Kuipers, E. J., Rabeneck, L., Young, G. P., Steele, R. J., Lieberman, D. & Goh, K. L. Jan 2015 In : Gut. 64, 1, p. 121-132 12 p.

    Research output: Contribution to journalArticle

  85. Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

    Brough, H. A., Liu, A. H., Sicherer, S., Makinson, K., Douiri, A., Brown, S. J., Stephens, A. C., McLean, W. H. I., Turcanu, V., Wood, R. A., Jones, S. M., Burks, W., Dawson, P., Stablein, D., Sampson, H. & Lack, G. Jan 2015 In : Journal of Allergy and Clinical Immunology. 135, 1, p. 164-170.e4 11 p.

    Research output: Contribution to journalArticle

  86. Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

    Dayalan Naidu, S., Kostov, R. V. & Dinkova-Kostova, A. T. Jan 2015 In : Trends in Pharmacological Sciences. 36, 1, p. 6-14 9 p.

    Research output: Contribution to journalArticle

  87. Viruses and disease: emerging concepts for prevention, diagnosis and treatment

    Herrington, C. S., Coates, P. J. & Duprex, W. P. Jan 2015 In : Journal of Pathology. 235, 2, p. 149-152 4 p.

    Research output: Contribution to journalArticle

  88. 3D Monte Carlo radiation transfer modelling of photodynamic therapy

    Campbell, C. L., Christison, C., Brown, C. T. A., Wood, K., Valentine, R. M. & Moseley, H. 2015 Biophotonics South America. Kurachi, C., Svanberg, K., Tromberg, B. J. & Bagnato, V. S. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 95311H. (Proceedings of SPIE; vol. 9531)(Progress in biomedical optics and imaging; vol. 16, no. 52)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  89. A multi-wavelength (u.v. to visible) laser system for early detection of oral cancer

    Najda, S. P., Perlin, P., Leszczynski, M., Slight, T. J., Meredith, W., Schemmann, M., Moseley, H., Woods, J. A., Valentine, R., Kalra, S., Mossey, P., Theaker, E., Macluskey, M., Mimnagh, G. & Mimnagh, W. 2015 Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII. Farkas, D. L., Nicolau, D. V. & Leif, R. C. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 932809. (Proceedings of SPIE; vol. 9328)(Progress in biomedical optics and imaging; vol. 16, no. 26)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  90. A novel excitation-emission wavelength model to facilitate the diagnosis of urinary bladder diseases

    Rafailov, I., Palmer, S., Litvinova, K., Dremin, V., Dunaev, A. & Nabi, G. 2015 Photonic Therapeutics and Diagnostics XI. Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Nuttal, A., Richter, C-P., Skala, M. C., Dewhirst, M. W., Tearney, G. J., Gregory, K. W., Marcu, L., Mandelis, A. & Morris, M. D. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93030W. (Proceedings of SPIE; vol. 9303)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  91. Biomarkers and novel agents in esophago-gastric cancer: are we making progress?

    Dahle-Smith, A. & Petty, R. D. 2015 In : Expert Review of Anticancer Therapy. 15, 9, p. 1103-1119 17 p.

    Research output: Contribution to journalArticle

  92. Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver

    Choughule, K. V., Locuson, C. W. & Coughtrie, M. W. H. 2015 In : Xenobiotica. 45, 6, p. 495-502 8 p.

    Research output: Contribution to journalArticle

  93. Discrimination of healthy and cancer cells of the bladder by metabolic state, based on autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 2015 Photonic Therapeutics and Diagnostics XI. Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Nuttal, A., Richter, C-P., Skala, M. C., Dewhirst, M. W., Tearney, G. J., Gregory, K. W., Marcu, L. & Mandelis, A. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93030T. (Proceedings of SPIE; vol. 9303)(Progress In Biomedical Optics And Imaging; vol. 16, no. 1)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  94. Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms

    Mowat, C., Digby, J., Strachan, J. A., Wilson, R., Carey, F. A., Fraser, C. G. & Steele, R. J. C. 2015 In : Gut. 8 p.

    Research output: Contribution to journalArticle

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