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Division of Cancer Research

  1. Motion estimation-based image enhancement in ultrasound imaging

    Morin, R., Basarab, A., Bidon, S. & Kouamé, D. Jul 2015 In : Ultrasonics. 60, p. 19-26 8 p.

    Research output: Contribution to journalArticle

  2. Choosing the best method to estimate the energy density of a population using food purchase data

    Wrieden, W. L., Armstrong, J., Anderson, A. S., Sherriff, A. & Barton, K. L. Apr 2015 In : Journal of Human Nutrition and Dietetics. 28, 2, p. 126-134 9 p.

    Research output: Contribution to journalArticle

  3. Nrf2 regulates ROS production by mitochondria and NADPH oxidase

    Kovac, S., Angelova, P. R., Holmström, K. M., Zhang, Y., Dinkova-Kostova, A. T. & Abramov, A. Y. Apr 2015 In : Biochimica et Biophysica Acta: General Subjects. 1850, 4, p. 794-801 8 p.

    Research output: Contribution to journalArticle

  4. Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

    Fleming, S. & 44 others Kovac, M., Navas, C., Horswell, S., Salm, M., Bardella, C., Rowan, A., Stares, M., Castro-Giner, F., Fisher, R., de Bruin, E. C., Kovacova, M., Gorman, M., Makino, S., Williams, J., Jaeger, E., Jones, A., Howarth, K., Larkin, J., Pickering, L., Gore, M., Nicol, D. L., Hazell, S., Stamp, G., O'Brien, T., Challacombe, B., Matthews, N., Phillimore, B., Begum, S., Rabinowitz, A., Varela, I., Chandra, A., Horsfield, C., Polson, A., Tran, M., Bhatt, R., Terracciano, L., Eppenberger-Castori, S., Protheroe, A., Maher, E., El Bahrawy, M., Ratcliffe, P., Heinimann, K., Swanton, C. & Tomlinson, I. 19 Mar 2015 In : Nature Communications. 6, 11 p.6336

    Research output: Contribution to journalArticle

  5. Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins

    Colin, D. J., Hain, K. O., Allan, L. A. & Clarke, P. R. 11 Mar 2015 In : Open Biology. 5, 13 p.140156

    Research output: Contribution to journalArticle

  6. Detection of urinary bladder cancer cells using redox ratio and double excitation wavelengths autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 1 Mar 2015 In : Biomedical Optics Express. 6, 3, p. 977-986 10 p.

    Research output: Contribution to journalArticle

  7. An Enhanced In Vivo Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) Model for Quantification of Drug Metabolism Enzymes

    MacLeod, A. K., Fallon, P. G., Sharp, S., Henderson, C. J., Wolf, C. R. & Huang, J. T-J. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 750-760 11 p.

    Research output: Contribution to journalArticle

  8. Biological variation: a still evolving facet of laboratory medicine

    Simundic, A. M., Bartlett, W. A. & Fraser, C. G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 189-190 2 p.

    Research output: Contribution to journalEditorial

  9. Calculation of limits for significant unidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 237-244 8 p.

    Research output: Contribution to journalArticle

  10. Distal nephron neoplasms

    Fleming, S. Mar 2015 In : Seminars in Diagnostic Pathology. 32, 2, p. 114-123 10 p.

    Research output: Contribution to journalArticle

  11. Laser-induced autofluorescence spectroscopy: Can it be of importance in detection of bladder lesions?

    Aboumarzouk, O., Valentine, R., Buist, R., Ahmad, S., Nabi, G., Eljamel, S., Moseley, H. & Kata, S. G. Mar 2015 In : Photodiagnosis and Photodynamic Therapy. 12, 1, p. 76-83 8 p.

    Research output: Contribution to journalArticle

  12. Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability

    Henderson, C. J., McLaughlin, L. A., Osuna-Cabello, M., Taylor, M., Gilbert, I., McLaren, A. W. & Wolf, C. R. 1 Feb 2015 In : Biochemical Journal. 465, 3, p. 479-488 10 p.

    Research output: Contribution to journalArticle

  13. Detection and characterisation of biopsy tissue using quantitative optical coherence elastography (OCE) in men with suspected prostate cancer

    Li, C., Guan, G., Ling, Y., Hsu, Y-T., Song, S., Huang, J. T-J., Lang, S., Wang, R. K., Huang, Z. & Nabi, G. 1 Feb 2015 In : Cancer Letters. 357, 1, p. 121-128 8 p.

    Research output: Contribution to journalArticle

  14. Insight from the air-skin interface

    O'Shaughnessy, R. F. L. & Brown, S. J. Feb 2015 In : Journal of Investigative Dermatology. 135, 2, p. 331-333 3 p.

    Research output: Contribution to journalComment/debate

  15. Terms and Symbols Used in Studies on Biological Variation: The Need for Harmonization

    Simundic, A. M., Kackov, S., Miler, M., Fraser, C. G. & Petersen, P. H. Feb 2015 In : Clinical Chemistry. 61, 2, p. 438-439 2 p.

    Research output: Contribution to journalLetter

  16. Thiel Embalming Method for Cadaver Preservation: A Review of New Training Model for Urologic Skills Training

    Healy, S. E., Rai, B. P., Biyani, C. S., Eisma, R., Soames, R. W. & Nabi, G. 9 Jan 2015 In : Urology. 85, 3, p. 499-504

    Research output: Contribution to journalArticle

  17. Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

    Brown, S. J. & 38 others Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I., Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S. & Cordell, H. J. 8 Jan 2015 In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticle

  18. An updated Asia Pacific Consensus Recommendations on colorectal cancer screening

    Sung, J. J. Y., Ng, S. C., Chan, F. K. L., Chiu, H. M., Kim, H. S., Matsuda, T., Ng, S. S. M., Lau, J. Y. W., Zheng, S., Adler, S., Reddy, N., Yeoh, K. G., Tsoi, K. K. F., Ching, J. Y. L., Kuipers, E. J., Rabeneck, L., Young, G. P., Steele, R. J., Lieberman, D. & Goh, K. L. Jan 2015 In : Gut. 64, 1, p. 121-132 12 p.

    Research output: Contribution to journalArticle

  19. Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

    Brough, H. A., Liu, A. H., Sicherer, S., Makinson, K., Douiri, A., Brown, S. J., Stephens, A. C., McLean, W. H. I., Turcanu, V., Wood, R. A., Jones, S. M., Burks, W., Dawson, P., Stablein, D., Sampson, H. & Lack, G. Jan 2015 In : Journal of Allergy and Clinical Immunology. 135, 1, p. 164-170.e4 11 p.

    Research output: Contribution to journalArticle

  20. Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

    Dayalan Naidu, S., Kostov, R. V. & Dinkova-Kostova, A. T. Jan 2015 In : Trends in Pharmacological Sciences. 36, 1, p. 6-14 9 p.

    Research output: Contribution to journalArticle

  21. Viruses and disease: emerging concepts for prevention, diagnosis and treatment

    Herrington, C. S., Coates, P. J. & Duprex, W. P. Jan 2015 In : Journal of Pathology. 235, 2, p. 149-152 4 p.

    Research output: Contribution to journalArticle

  22. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., MacLeod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & The BeWEL team. 2015 In : Colorectal Disease. 14 p.

    Research output: Contribution to journalArticle

  23. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. 2015 In : Journal of Investigative Dermatology. 12 p.

    Research output: Contribution to journalLetter

  24. The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

    Woods, J. A., Evans, A., Forbes, P. D., Coates, P. J., Gardner, J., Valentine, R. M., Ibbotson, S. H., Ferguson, J., Fricker, C. & Moseley, H. 2015 In : Photodermatology, Photoimmunology & Photomedicine. 8 p.

    Research output: Contribution to journalArticle

  25. Trends in socio-economic inequalities in the Scottish diet: 2001-2009

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. 2015 In : Public Health Nutrition. 12 p.

    Research output: Contribution to journalArticle

  26. Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression

    Rushworth, L. K., Kidger, A. M., Delavaine, L., Stewart, G., van Schelven, S., Davidson, J., Bryant, C. J., Caddye, E., East, P., Caunt, C. J. & Keyse, S. M. 23 Dec 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. 18267-18272 6 p.

    Research output: Contribution to journalArticle

  27. The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site

    Orzol, P., Holcakova, J., Nekulova, M., Nenutil, R., Vojtesek, B. & Coates, P. J. 16 Dec 2014 In : Histology and Histopathology.

    Research output: Contribution to journalArticle

  28. Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells

    Schoenherr, C., Serrels, B., Proby, C., Cunningham, D. L., Findlay, J. E., Baillie, G. S., Heath, J. K. & Frame, M. C. 15 Dec 2014 In : Journal of Cell Science. 127, 24, p. 5303-5316 14 p.

    Research output: Contribution to journalArticle

  29. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

    Mudie, S., Bandarra, D., Batie, M., Biddlestone, J., Moniz, S., Ortmann, B., Shmakova, A. & Rocha, S. 15 Dec 2014 In : Cell Cycle. 13, 24, p. 3878-3891 14 p.

    Research output: Contribution to journalArticle

  30. Quantitative elasticity measurement of urinary bladder wall using laser-induced surface acoustic waves

    Li, C., Guan, G., Zhang, F., Song, S., Wang, R. K., Huang, Z. & Nabi, G. 1 Dec 2014 In : Biomedical Optics Express. 5, 12, p. 4313-4328 16 p.

    Research output: Contribution to journalArticle

  31. Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cells

    den Breems, N. Y., Nguyen, L. K. & Kulasiri, D. Dec 2014 In : Bio Systems. 126, p. 27-40 14 p.

    Research output: Contribution to journalArticle

  32. Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

    Nijenhuis, W., Vallardi, G., Teixeira, A., Kops, G. J. P. L. & Saurin, A. T. Dec 2014 In : Nature Cell Biology. 16, 12, p. 1257-1264 8 p.

    Research output: Contribution to journalLetter

  33. Shear-wave elastography contributes to accurate tumour size estimation when assessing small breast cancers

    Mullen, R., Thompson, J. M., Moussa, O., Vinnicombe, S. & Evans, A. Dec 2014 In : Clinical Radiology. 69, 12, p. 1259-1263 5 p.

    Research output: Contribution to journalArticle

  34. Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients

    Fleming, S. & 37 others Gill, A. J., Hes, O., Papathomas, T., Sedivcová, M., Tan, P. H., Agaimy, A., Andresen, P. A., Kedziora, A., Clarkson, A., Toon, C. W., Sioson, L., Watson, N., Chou, A., Paik, J., Clifton-Bligh, R. J., Robinson, B. G., Benn, D. E., Hills, K., Maclean, F., Niemeijer, N. D., Vlatkovic, L., Hartmann, A., Corssmit, E. P. M., van Leenders, G. J. L. H., Przybycin, C., McKenney, J. K., Magi-Galluzzi, C., Yilmaz, A., Yu, D., Nicoll, K. D., Yong, J. L., Sibony, M., Yakirevich, E., Chow, C. W., Miettinen, M., Michal, M. & Trpkov, K. Dec 2014 In : American Journal of Surgical Pathology. 38, 12, p. 1588-1602 15 p.

    Research output: Contribution to journalArticle

  35. Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel cyanoenone and enone benzenesulfonamides

    Ghorab, M. M., Higgins, M., Alsaid, M. S., Arafa, R. K., Shahat, A. A. & Dinkova-Kostova, A. T. Dec 2014 In : Journal of Enzyme Inhibition and Medicinal Chemistry. 29, 6, p. 840-845 6 p.

    Research output: Contribution to journalArticle

  36. HDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agents

    McMahon, M., Campbell, K. H., MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 26 Nov 2014 In : PLoS ONE. 9, 11, e114055

    Research output: Contribution to journalArticle

  37. Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma

    Drew, J. E., Farquharson, A. J., Mayer, C. D., Vase, H. F., Coates, P. J., Steele, R. J. & Carey, F. A. 25 Nov 2014 In : PLoS ONE. 9, 11, 20 p.e113071

    Research output: Contribution to journalArticle

  38. 5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release

    Hothersall, J. D., Alexander, A., Samson, A. J., Moffat, C., Bollan, K. A. & Connolly, C. N. 14 Nov 2014 In : Journal of Biological Chemistry. 289, 46, p. 32020-32029 10 p.

    Research output: Contribution to journalArticle

  39. Malignancy within a tail gut cyst: a case of retrorectal carcinoid tumour

    Abukar, A. A., Parcell, B. J., Lim, C. B., Patil, P. V., Ramsanahie, A., Carey, F., Steele, R. J. C. & Thaha, M. A. 13 Nov 2014 In : Case Reports in Surgery. 2014, 4 p.454502

    Research output: Contribution to journalArticle

  40. Monitoring Keap1-Nrf2 interactions in single live cells

    Baird, L., Swift, S., Llères, D. & Dinkova-Kostova, A. T. 1 Nov 2014 In : Biotechnology Advances. 32, 6, p. 1133-1144 12 p.

    Research output: Contribution to journalArticle

  41. Impact of faecal occult blood test screening on emergency admissions and short-term outcomes for colorectal cancer

    Libby, G., Brewster, D. H. & Steele, R. J. C. Nov 2014 In : British Journal of Surgery. 101, 12, p. 1607-1615 9 p.

    Research output: Contribution to journalArticle

  42. Laparoscopic nephrectomy for Adult Polycystic Kidney Disease (APKD): safety, feasibility and early outcomes

    Williamson, A., Paterson, S., Erolin, C., Sweeney, C., Townell, N. & Nabi, G. Nov 2014 In : Journal of Endourology. 28, 11, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  43. Risk of AKI with gentamicin as surgical prophylaxis

    Bell, S., Davey, P., Nathwani, D., Marwick, C., Vadiveloo, T., Sneddon, J., Patton, A., Bennie, M., Fleming, S. & Donnan, P. T. Nov 2014 In : Journal of the American Society of Nephrology. 25, 11, p. 2625-2632 8 p.

    Research output: Contribution to journalArticle

  44. Non-redundant Raman imaging using optical eigenmodes

    Kosmeier, S., Zolotovskaya, S., De Luca, A. C., Riches, A., Herrington, C. S., Dholakia, K. & Mazilu, M. 20 Oct 2014 In : Optica. 1, 4, p. 257-263 7 p.

    Research output: Contribution to journalArticle

  45. Fertility preservation in men with cancer

    Tournaye, H., Dohle, G. R. & Barratt, C. L. R. 4 Oct 2014 In : Lancet. 384, 9950, p. 1295-1301 7 p.

    Research output: Contribution to journalArticle

  46. Robotic or open radical cystectomy, which is safer? a systematic review and meta-analysis of comparative studies

    Ishii, H., Rai, B. P., Stolzenburg, J-U., Bose, P., Chlosta, P. L., Somani, B. K., Nabi, G., Qazi, H. A. R., Rajbabu, K., Kynaston, H. & Aboumarzouk, O. M. 2 Oct 2014 In : Journal of Endourology. 28, 10, p. 1215-1223 9 p.

    Research output: Contribution to journalArticle

  47. NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

    South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M. Oct 2014 In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638

    Research output: Contribution to journalArticle

  48. Colorectal cancer screening

    Steele, R. J. C. Oct 2014 In : British Journal of Surgery. 101, 11, p. 1338-1340 3 p.

    Research output: Contribution to journalArticle

  49. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

    Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P. Oct 2014 In : Stem Cells. 32, 10, p. 2605-2615

    Research output: Contribution to journalArticle

  50. Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

    Simpson, E. L., Chalmers, J. R., Hanifin, J. M., Thomas, K. S., Cork, M. J., McLean, W. H. I., Brown, S. J., Chen, Z., Chen, Y. & Williams, H. C. Oct 2014 In : Journal of Allergy and Clinical Immunology. 134, 4, p. 818-823 6 p.

    Research output: Contribution to journalArticle

  51. Follow-up in early breast cancer - a surgical and radiological perceptive

    Dunn, J. A., Donnelly, P. K., Marshall, A., Wilcox, M., Watson, E., Young, A., Balmer, C., Ramirez, M., Hartup, S., Maxwell, A. J., Evans, A. J. & on behalf of the Mammo-50 trial management group Oct 2014 In : Clinical Oncology. 26, 10, p. 625-629 5 p.

    Research output: Contribution to journalEditorial

  52. Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

    Brough, H. A., Simpson, A., Makinson, K., Hankinson, J., Brown, S., Douiri, A., Belgrave, D. C. M., Penagos, M., Stephens, A. C., McLean, W. H. I., Turcanu, V., Nicolaou, N., Custovic, A. & Lack, G. Oct 2014 In : Journal of Allergy and Clinical Immunology. 134, 4, p. 867-875.e1 10 p.

    Research output: Contribution to journalArticle

  53. Phenotype standardisation of angioedema in the head and neck region caused by agents acting on the angiotensin system

    Wadelius, M., Marshall, S. E., Islander, G., Nordang, L., Karawajczyk, M., Yue, Q-Y., Terreehorst, I., Baranova, E. V., Hugosson, S., Sköldefors, K., Pirmohamed, M., Maitland van der Zee, A-H., Alfirevic, A., Hallberg, P. & Palmer, C. N. A. Oct 2014 In : Clinical Pharmacology & Therapeutics. 96, 4, p. 477-481

    Research output: Contribution to journalScientific review

  54. Sugars and health - risk assessment to risk management

    Anderson, A. S. Oct 2014 In : Public Health Nutrition. 17, 10, p. 2148-2150 3 p.

    Research output: Contribution to journalComment/debate

  55. Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes

    Tsujita, T., Peirce, V., Baird, L., Matsuyama, Y., Takaku, M., Walsh, S. V., Griffin, J. L., Uruno, A., Yamamoto, M. & Hayes, J. D. Oct 2014 In : Molecular and Cellular Biology. 34, 20, p. 3800-3816 17 p.

    Research output: Contribution to journalArticle

  56. Risk determination and prevention of breast cancer

    Howell, A., Anderson, A. S., Clarke, R. B., Duffy, S. W., Evans, D. G., Garcia-Closas, M., Gescher, A. J., Key, T. J., Saxton, J. M. & Harvie, M. N. 28 Sep 2014 In : Breast Cancer Research. 16, 5, 19 p.446

    Research output: Contribution to journalArticle

  57. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol

    Holt, A-M., Jancey, J., Lee, A. H., Kerr, D. A., Hills, A. P., Anderson, A. S. & Howat, P. A. 25 Sep 2014 In : BMJ Open. 4, 9, 8 p.e005107

    Research output: Contribution to journalArticle

  58. Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery

    El-Mokadem, I., Fitzpatrick, J., Bondad, J., Rauchhaus, P., Cunningham, J., Pratt, N., Fleming, S. & Nabi, G. 23 Sep 2014 In : British Journal of Cancer. 111, 7, p. 1381-1390 10 p.

    Research output: Contribution to journalArticle

  59. Dietary outcomes of a community based intervention for mothers of young children: a randomised controlled trial

    Jancey, J. M., Dos Remedios Monteiro, S. M., Dhaliwal, S. S., Howat, P. A., Burns, S., Hills, A. P. & Anderson, A. S. 23 Sep 2014 In : International Journal of Behavioral Nutrition and Physical Activity. 11, 1, 9 p.120

    Research output: Contribution to journalArticle

  60. Digital mammographic density and breast cancer risk: a case-control study of six alternative density assessment methods

    Eng, A., Gallant, Z., Shepherd, J., McCormack, V., Li, J., Dowsett, M., Vinnicombe, S., Allen, S. & dos-Santos-Silva, I. 20 Sep 2014 In : Breast Cancer Research. 16, 5, 12 p.439

    Research output: Contribution to journalArticle

  61. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.

    Sparks, A., Dayal, S., Das, J., Robertson, P., Menendez, S. & Saville, M. K. 18 Sep 2014 In : Oncogene. 33, 38, p. 4685-4696 12 p.

    Research output: Contribution to journalArticle

  62. Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines

    Sawers, L., Ferguson, M. J., Ihrig, B. R., Young, H. C., Chakravarty, P., Wolf, C. R. & Smith, G. 9 Sep 2014 In : British Journal of Cancer. 111, 6, p. 1150-1158

    Research output: Contribution to journalArticle

  63. Mutations in GRHL2 result in an autosomal-recessive ectodermal dysplasia syndrome

    Petrof, G., Nanda, A., Howden, J., Takeichi, T., McMillan, J. R., Aristodemou, S., Ozoemena, L., Liu, L., South, A. P., Pourreyron, C., Dafou, D., Proudfoot, L. E., Al-Ajmi, H., Akiyama, M., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A. 4 Sep 2014 In : American Journal of Human Genetics. 95, 3, p. 308-314 7 p.

    Research output: Contribution to journalArticle

  64. Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase

    Müllers, E., Cascales, H. S., Jaiswal, H., Saurin, A. T. & Lindqvist, A. 1 Sep 2014 In : Cell Cycle. 13, 17, p. 2733-2743 11 p.

    Research output: Contribution to journalArticle

  65. Genes involved in epithelial differentiation and development are differentially expressed in oral and genital lichen planus epithelium compared to normal epithelium

    Danielsson, K., Coates, P. J., Ebrahimi, M., Nylander, E., Wahlin, Y-B. & Nylander, K. Sep 2014 In : Acta Dermato-Venereologica. 94, 5, p. 526-530 5 p.

    Research output: Contribution to journalArticle

  66. Importance of β-defensins in sperm function

    Dorin, J. R. & Barratt, C. L. Sep 2014 In : Molecular Human Reproduction. 20, 9, p. 821-826 6 p.

    Research output: Contribution to journalArticle

  67. Leporid immunoglobulin G shows evidence of strong selective pressure on the hinge and CH3 domains

    Pinheiro, A., Woof, J. M., Almeida, T., Abrantes, J., Alves, P. C., Gortázar, C. & Esteves, P. J. Sep 2014 In : Open Biology. 4, 9, 9 p.140088

    Research output: Contribution to journalArticle

  68. Malignancy-associated hyperamylasaemia

    Srivastava, R., Murphy, M. J. & Fraser, C. G. Sep 2014 In : Annals of Clinical Biochemistry. 51, 5, p. 619 1 p.

    Research output: Contribution to journalLetter

  69. Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

    Marcel, V., Fernandes, K., Terrier, O., Lane, D. P. & Bourdon, J-C. Sep 2014 In : Cell Death & Differentiation. 21, p. 1377-1387 11 p.

    Research output: Contribution to journalArticle

  70. Progress in skin cancer: the U.K. experience

    Leigh, I. M. Sep 2014 In : British Journal of Dermatology. 171, 3, p. 443-445 3 p.

    Research output: Contribution to journalEditorial

  71. The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

    Salmond, R. J., Brownlie, R. J., Morrison, V. L. & Zamoyska, R. Sep 2014 In : Nature Immunology. 15, 9, p. 875-883 8 p.

    Research output: Contribution to journalArticle

  72. Epigenetics in diagnosis, prognostic assessment and treatment of cancer: An update

    Hatzimichael, E., Lagos, K., Sim, V. R., Briasoulis, E. & Crook, T. 26 Aug 2014 In : EXCLI Journal. 13, p. 954-976 23 p.

    Research output: Contribution to journalArticle

  73. BRCA1 is a histone-H2A-specific ubiquitin ligase

    Kalb, R., Mallery, D. L., Larkin, C., Huang, J. T. J. & Hiom, K. 21 Aug 2014 In : Cell Reports. 8, 4, p. 999-1005 7 p.

    Research output: Contribution to journalArticle

  74. Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation

    Hamilton, D. L., Philp, A., MacKenzie, M. G., Patton, A., Towler, M. C., Gallagher, I. J., Bodine, S. C. & Baar, K. 15 Aug 2014 In : American Journal of Physiology, Endocrinology and Metabolism. 307, 4, p. E365-E373 9 p.

    Research output: Contribution to journalArticle

  75. Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR

    Braeuning, A., Gavrilov, A., Brown, S., Wolf, C. R., Henderson, C. J. & Schwarz, M. 1 Aug 2014 In : Toxicological Sciences. 140, 2, p. 259-70 12 p.

    Research output: Contribution to journalArticle

  76. Accuracy of non-operative identification of the sentinel lymph node using combined gamma and ultrasound scanning

    Whelehan, P., Vinnicombe, S. J., Brown, D. C., McLean, D. & Evans, A. Aug 2014 In : Clinical Radiology. 69, 8, p. 849-852 4 p.

    Research output: Contribution to journalArticle

  77. An investigation into the MMP1 gene promoter region polymorphism - 1607 2G with recessive dystrophic epidermolysis bullosa disease severity in northeastern Mexican patients

    Garza-Gómez, J., Cerda-Flores, R. M., Gómez-Flores, M., Salas-Alanís, J. C., Ocampo-Candiani, J., Martínez-Garza, L. E., South, A. P. & Gallardo-Blanco, H. L. Aug 2014 In : International Journal of Dermatology. 53, 8, p. 985-990 6 p.

    Research output: Contribution to journalArticle

  78. Chemical tuning enhances both potency toward Nrf2 and in vitro therapeutic index of triterpenoids

    Copple, I. M., Shelton, L. M., Walsh, J., Kratschmar, D. V., Lister, A., Odermatt, A., Goldring, C. E., Dinkova-Kostova, A. T., Honda, T. & Park, B. K. Aug 2014 In : Toxicological Sciences. 140, 2, p. 462-469 8 p.

    Research output: Contribution to journalArticle

  79. Evidence for aldosterone-dependent growth of renal cell carcinoma

    King, S., Bray, S., Galbraith, S., Christie, L. & Fleming, S. Aug 2014 In : International Journal of Experimental Pathology. 95, 4, p. 244-250 7 p.

    Research output: Contribution to journalArticle

  80. Faecal haemoglobin concentrations vary with sex and age, but data are not transferable across geography for colorectal cancer screening

    Fraser, C. G., Rubeca, T., Rapi, S., Chen, L-S. & Chen, H-H. Aug 2014 In : Clinical Chemistry and Laboratory Medicine. 52, 8, p. 1211-6 6 p.

    Research output: Contribution to journalArticle

  81. Synthesis of 13C215N2-labeled anti-inflammatory and cytoprotective tricyclic bis(cyanoenone) ([13C215N2]-TBE-31) as an internal standard for quantification by stable isotope dilution LC-MS method

    Zheng, S., Huang, J. T. -J., Knatko, E. V., Sharp, S., Higgins, M., Ojima, I., Dinkova-Kostova, A. T. & Honda, T. Aug 2014 In : Journal of Labelled Compounds & Radiopharmaceuticals. 57, 10, p. 606-610 5 p.

    Research output: Contribution to journalArticle

  82. The SNAP trial: a randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - clinical effectiveness and safety until 2 years after delivery, with economic evaluation

    Cooper, S., Lewis, S., Thornton, J. G., Marlow, N., Watts, K., Britton, J., Grainge, M. J., Taggar, J., Essex, H., Parrott, S., Dickinson, A., Whitemore, R., Coleman, T. & Smoking, Nicotine and Pregnancy (SNAP) Trial Team Aug 2014 In : Health Technology Assessment. 18, 54, p. 1-128 128 p.

    Research output: Contribution to journalArticle

  83. Therapeutic targeting of integrin αvβ6 in breast cancer

    Moore, K. M. , Thomas, G. J. , Duffy, S. W. , Warwick, J. , Gabe, R. , Chou, P. , Ellis, I. O. , Green, A. R. , Haider, S. , Brouilette, K. , Saha, A. , Vallath, S. , Bowen, R. , Chelala, C. , Eccles, D. , Tapper, W. J. , Thompson, A. M. , Quinlan, P. , Jordan, L. , Gillett, C. & 8 others Brentnall, A., Violette, S., Weinreb, P. H., Kendrew, J., Barry, S. T., Hart, I. R., Jones, J. L. & Marshall, J. F. Aug 2014 In : Journal of the National Cancer Institute. 106, 8, 14 p.dju169

    Research output: Contribution to journalArticle

  84. Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa

    Cogan, J., Weinstein, J., Wang, X., Hou, Y., Martin, S., South, A. P., Woodley, D. T. & Chen, M. 23 Jul 2014 In : Molecular Therapy.

    Research output: Contribution to journalArticle

  85. Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II

    Magnani, F., Pappas, C. G., Crook, T., Magafa, V., Cordopatis, P., Ishiguro, S., Ohta, N., Selent, J., Bosnyak, S., Jones, E. S., Gerothanassis, I. P., Tamura, M., Widdop, R. E. & Tzakos, A. G. 18 Jul 2014 In : ACS Chemical Biology. 9, 7, p. 1420-1425 6 p.

    Research output: Contribution to journalArticle

  86. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  87. Energy density of the Scottish diet estimated from food purchase data: relationship with socio-economic position and dietary targets

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. 14 Jul 2014 In : British Journal of Nutrition. 112, 1, p. 80-88 9 p.

    Research output: Contribution to journalArticle

  88. Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast

    Thomas, J., Hanby, A., Pinder, S. E., Ball, G., Lawrence, G., Maxwell, A., Wallis, M., Evans, A., Dobson, H., Clements, K., Thompson, A. & Sloane Project Steering Group Jul 2014 In : European Journal of Cancer. 50, 11, p. 1880-1890 11 p.

    Research output: Contribution to journalArticle

  89. Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

    Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J. Jul 2014 In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

    Research output: Contribution to journalArticle

  90. Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status

    Bouchalova, P., Nenutil, R., Muller, P., Hrstka, R., Appleyard, M. V., Murray, K., Jordan, L. B., Purdie, C. A., Quinlan, P., Thompson, A. M., Vojtesek, B. & Coates, P. J. Jul 2014 In : Journal of Pathology. 233, 3, p. 238-246 9 p.

    Research output: Contribution to journalArticle

  91. A data standard for sourcing fit-for-purpose biological samples in an integrated virtual network of biobanks

    Confederation of Cancer Biobanks (CCB) Working Group 3 Jun 2014 In : Biopreservation and Biobanking. 12, 3, p. 184-191 8 p.

    Research output: Contribution to journalArticle

  92. Comparative cancer survival in European countries

    Munro, A. J. Jun 2014 In : British Medical Bulletin. 110, 1, p. 5-22 18 p.

    Research output: Contribution to journalArticle

  93. Deprivation and faecal haemoglobin: implications for bowel cancer screening

    Digby, J., McDonald, P. J., Strachan, J. A., Libby, G., Steele, R. J. C. & Fraser, C. G. Jun 2014 In : Journal of Medical Screening. 21, 2, p. 95-97 3 p.

    Research output: Contribution to journalArticle

  94. Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization: a solution for practical application

    Li, C., Guan, G., Zhang, F., Nabi, G., Wang, R. K. & Huang, Z. 1 May 2014 In : Biomedical Optics Express. 5, 5, p. 1403-1418 16 p.

    Research output: Contribution to journalArticle

  95. The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers

    Iyer, R. S., Nicol, S. M., Quinlan, P. R., Thompson, A. M., Meek, D. W. & Fuller-Pace, F. V. 1 May 2014 In : Cell cycle (Georgetown, Tex.). 13, 9, p. 1413-1423 11 p.

    Research output: Contribution to journalArticle

  96. Discrimination of bladder cancer cells from normal urothelial cells with high specificity and sensitivity: combined application of AFM and modulated Raman spectroscopy

    Canetta, E., Riches, A., Borger, E., Herrington, S., Dholakia, K. & Adya, A. K. May 2014 In : Acta Biomaterialia. 10, 5, p. 2043-2055

    Research output: Contribution to journalArticle

  97. Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue

    Rentoft, M., Coates, P. J., Loljung, L., Wilms, T., Laurell, G. & Nylander, K. May 2014 In : Tumor Biology. 35, 5, p. 4191-4198 8 p.

    Research output: Contribution to journalArticle

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