Discovery - University of Dundee - Online Publications

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Division of Cancer Research

  1. Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

    Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Le Ber, I., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y. 10 May 2017 In : Scientific Reports. 7, p. 1-14 14 p., 1666

    Research output: Contribution to journalArticle

  2. Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis

    Terranova, R., Vitobello, A., Del Rio Espinola, A., Wolf, C. R., Schwarz, M., Thomson, J. M., Meehan, R. & Moggs, J. G. Apr 2017 In : Current Opinion in Toxicology. 3, p. 62-70 9 p.

    Research output: Contribution to journalReview article

  3. Fatal attractions? Correlations of CXCL12–CXCR4–CXCR7 expression with disease progression in melanoma and Kaposi sarcoma

    Spender, L. C. & Inman, G. J. 20 Dec 2016 In : British Journal of Dermatology. 175, 6, p. 1140-1141 2 p.

    Research output: Contribution to journalComment/debate

  4. Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

    Hayes, J. D., Ebisine, K., Sharma, R. S., Chowdhry, S., Dinkova-Kostova, A. T. & Sutherland, C. Dec 2016 In : Current Opinion in Toxicology. 1, p. 92-103 12 p.

    Research output: Contribution to journalReview article

  5. The multifaceted role of Nrf2 in mitochondrial function

    Holmström, K. M., Kostov, R. V. & Dinkova-Kostova, A. T. Dec 2016 In : Current Opinion in Toxicology. 1, p. 80-91 12 p.

    Research output: Contribution to journalReview article

  6. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  7. The ClearPET/XPAD prototype: Development of a simultaneous PET/CT scanner for mice

    Hamonet, M., Dupont, M., Fabiani, T., Cassol, F., Boursier, Y., Bonissent, A., Debarbieux, F., Pottier, G., Bidaut, L. & Morel, C. 3 Oct 2016 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015. Institute of Electrical and Electronics Engineers Inc., p. 1-3 3 p. 7582074

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  8. Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes

    McNeilly, A. D., Gallagher, J. R., Dinkova-Kostova, A. T., Hayes, J. D., Sharkey, J., Ashford, M. L. J. & McCrimmon, R. J. 1 Oct 2016 In : Diabetes. 65, 10, p. 3151-3160 10 p.

    Research output: Contribution to journalArticle

  9. Tumour suppressor gene (CDKNA2) status on chromosome 9p in resected renal tissue improves prognosis of localised kidney cancer

    El-Mokadem, I., Kidd, T., Pratt, N., Fleming, S. & Nabi, G. 22 Sep 2016 In : Oncotarget. 7, 45, p. 1-10 10 p.

    Research output: Contribution to journalArticle

  10. Variaciones anatómicas del sistema venoso ácigos: Clasificación y relevancia clínica

    Dahran, N. & Soames, R. 1 Sep 2016 In : International Journal of Morphology. 34, 3, p. 1128-1136 9 p.

    Research output: Contribution to journalArticle

  11. CREBBP mutation in human cutaneous squamous cell carcinoma

    Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Tucker, S., Arron, S. T., Mchugh, A., Xue, D. J., Dayal, J. H. S., Harwood, C. A., Leigh, I. M., Proby, C. M. & South, A. P. Aug 2016 In : Experimental Dermatology. 25, 8, p. 650-651 2 p.

    Research output: Contribution to journalLetter

  12. Rhodiola rosea L.: from golden root to green cell factories

    Marchev, A. S., Dinkova-Kostova, A. T., György, Z., Mirmazloum, I., Aneva, I. Y. & Georgiev, M. I. Aug 2016 In : Phytochemistry Reviews. 15, 4, p. 515-536 22 p.

    Research output: Contribution to journalArticle

  13. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models

    Quinti, L. , Casale, M. , Moniot, S. , Pais, T. F. , Van Kanegan, M. J. , Kaltenbach, L. S. , Pallos, J. , Lim, R. G. , Naidu, S. D. , Runne, H. , Meisel, L. , Rauf, N. A. , Leyfer, D. , Maxwell, M. M. , Saiah, E. , Landers, J. E. , Luthi-Carter, R. , Abagyan, R. , Dinkova-Kostova, A. T. , Steegborn, C. & 4 others Marsh, J. L., Lo, D. C., Thompson, L. M. & Kazantsev, A. G. 21 Jul 2016 In : Cell Chemical Biology. 23, 7, p. 849-861 13 p.

    Research output: Contribution to journalArticle

  14. Exosome-mediated transfer from the tumor microenvironment increases TGFβ signaling in squamous cell carcinoma

    Languino, L. R., Singh, A., Prisco, M., Inman, G. J., Luginbuhl, A., Curry, J. M. & South, A. P. 30 May 2016 In : American Journal of Translational Research. 8, 5, p. 2432-2437 6 p.

    Research output: Contribution to journalArticle

  15. Nrf2 activation in the treatment of neurodegenerative diseases: A focus on its role in mitochondrial bioenergetics and function

    Esteras, N., Dinkova-Kostova, A. T. & Abramov, A. Y. May 2016 In : Biological Chemistry. 397, 5, p. 383-400 18 p.

    Research output: Contribution to journalArticle

  16. The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

    Mao, X., Gauche, C., Coughtrie, M. W. H., Bui, C., Gulberti, S., Merhi-Soussi, F., Ramalanjaona, N., Bertin-Jung, I., Diot, A., Dumas, D., De Freitas Caires, N., Thompson, A. M., Bourdon, J-C., Ouzzine, M. & Fournel-Gigleux, S. 4 Apr 2016 In : Oncogene. 35, p. 5043-5055 13 p.

    Research output: Contribution to journalArticle

  17. Making the invisible visible

    van Steensel, M. A. M. 1 Apr 2016 In : Seminars in Cell & Developmental Biology. 52, p. 58-65 8 p.

    Research output: Contribution to journalBook/Film/Article review

  18. Chemical constituents and NAD(P)H:Quinone oxidoreductase 1 (NQO1) inducer activity of Teucrium oliverianum Ging. ex Benth

    Shahat, A. A., Alsaid, M. S., Khan, J. A., Higgins, M. & Dinkova-Kostova, A. T. Apr 2016 In : Indian Journal of Traditional Knowledge. 15, 2, p. 232-236 5 p.

    Research output: Contribution to journalArticle

  19. Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile

    Brinkhuizen, T., van Geel, M., Denil, S. L. I. J., De Meyer, T., Kelleners-Smeets, N. W. J., Lohuis, P. J. F. M., Hoebers, F. J. P., Winnepenninckx, V. J. L., van Steensel, M. A. M. & Mosterd, K. Apr 2016 In : Experimental Dermatology. 25, 4, p. 316-318 3 p.

    Research output: Contribution to journalLetter

  20. Synthesis, molecular modeling and NAD(P)H: quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives

    Ghorab, M. M., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T., Shahat, A. A., Elghazawy, N. H. & Arafa, R. K. Apr 2016 In : Journal of Enzyme Inhibition and Medicinal Chemistry. 31, 6, p. 1612-1618 7 p.

    Research output: Contribution to journalArticle

  21. Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer

    Palmer, S., Litvinova, K., Dunaev, A., Fleming, S., McGloin, D. & Nabi, G. 7 Mar 2016 In : Biomedical Optics Express. 7, 4, p. 1193-2000 8 p.

    Research output: Contribution to journalArticle

  22. The loop structure and the RNA helicase p72/DDX17 influence the processing efficiency of the mice miR-132

    Remenyi, J., Bajan, S., Fuller-Pace, F. V., Arthur, J. S. C. & Hutvagner, G. 7 Mar 2016 In : Scientific Reports. 6, p. 1-13 13 p., 22848

    Research output: Contribution to journalArticle

  23. Photodynamic diagnostic ureterorenoscopy: a valuable tool in the detection of upper urinary tract tumour

    Kata, S. G., Aboumarzouk, O. M., Zreik, A., Somani, B., Ahmad, S., Nabi, G., Buist, R., Goodman, C., Chlosta, P., Golabek, T. & Moseley, H. Mar 2016 In : Photodiagnosis and Photodynamic Therapy. 13, p. 255-260 6 p.

    Research output: Contribution to journalArticle

  24. A spontaneous increase in intracellular Ca2+ in metaphase II human oocytes in vitro can be prevented by drugs targeting ATP-sensitive K+ channels

    Fernandes, G., Dasai, N., Kozlova, N., Mojadadi, A., Gall, M., Drew, E., Barratt, E., Madamidola, O. A., Brown, S. G., Milne, A. M., Martins Da Silva, S. J., Whalley, K. M., Barratt, C. L. R. & Jovanovic, A. Feb 2016 In : Human Reproduction. 31, 2, p. 287-297 11 p.

    Research output: Contribution to journalArticle

  25. Hand dermatitis in construction workers: a lesson in genetic epidemiology

    Brown, S. J. Feb 2016 In : British Journal of Dermatology. 174, 2, p. 263-265 3 p.

    Research output: Contribution to journalComment/debate

  26. International Consortium on Mammographic Density: methodology and population diversity captured across 22 countries

    McCormack, V. A. , Burton, A. , dos-Santos-Silva, I. , Hipwell, J. H. , Dickens, C. , Salem, D. , Kamal, R. , Hartman, M. , Lee, C. P. L. , Chia, K-S. , Ozmen, V. , Aribal, M. E. , Flugelman, A. A. , Lajous, M. , Lopez-Riduara, R. , Rice, M. , Romieu, I. , Ursin, G. , Qureshi, S. , Ma, H. & 36 others Lee, E., van Gils, C. H., Wanders, J. O. P., Vinayak, S., Ndumia, R., Allen, S., Vinnicombe, S., Moss, S., Won Lee, J., Kim, J., Pereira, A., Garmendia, M. L., Sirous, R., Sirous, M., Peplonska, B., Bukowska, A., Tamimi, R. M., Bertrand, K., Nagata, C., Kwong, A., Vachon, C., Scott, C., Perez-Gomez, B., Pollan, M., Maskarinec, G., Giles, G., Hopper, J., Stone, J., Rajaram, N., Teo, S-H., Mariapun, S., Yaffe, M. J., Schüz, J., Chiarelli, A. M., Linton, L. & Boyd, N. F. Feb 2016 In : Cancer Epidemiology. 40, p. 141-151 11 p.

    Research output: Contribution to journalArticle

  27. LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner

    Kramer, H. B., Lai, C-F., Patel, H., Periyasamy, M., Lin, M-L., Feller, S. M., Fuller-Pace, F. V., Meek, D. W., Ali, S. & Buluwela, L. 29 Jan 2016 In : Nucleic Acids Research. 44, 2, p. 582-594 13 p.

    Research output: Contribution to journalArticle

  28. Can angiotensin-converting enzyme inhibitors reduce the incidence, severity, and duration of radiation proctitis?

    Alashkham, A., Paterson, C., Rauchhaus, P. & Nabi, G. 1 Jan 2016 In : International Journal of Radiation Oncology Biology Physics. 94, 1, p. 93-101 9 p.

    Research output: Contribution to journalArticle

  29. Dual-specificity MAP kinase (MAPK) phosphatases (MKPs) and their involvement in cancer

    Kidger, A. M. & Keyse, S. M. 1 Jan 2016 Protein Tyrosine Phosphatases in Cancer. Neel, B. G. & Tonks, N. K. (eds.). New York: Springer New York, p. 201-231 31 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. Detection of DCIS and reduced invasive interval cancers

    Evans, A. Jan 2016 In : Lancet Oncology. 17, 1, p. 14-15 2 p.

    Research output: Contribution to journalComment/debate

  31. Re: A proposal to standardize reporting units for fecal immunochemical tests for hemoglobin

    Fraser, C. G., Rapi, S. & Rubeca, T. Jan 2016 In : Journal of the National Cancer Institute. 108, 1, 2 p., djv312

    Research output: Contribution to journalLetter

  32. The multifaceted role of sulforaphane in protection against uv radiation-mediated skin damage

    Benedict, A. L., Knatko, E. V., Kostov, R. V., Zhang, Y., Higgins, M., Kalra, S., Fahey, J. W., Ibbotson, S. H., Proby, C. M., Talalay, P. & Dinkova-Kostova, A. T. Jan 2016 Broccoli: Cultivation, Nutritional Properties and Effects on Health. Nova Science Publishers, Inc., p. 185-208 24 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  33. NAD(P)H: Quinone oxidoreductase 1 inducer activity of novel 4-aminoquinazoline derivatives

    Ghorab, M. M., Alsaid, M. S., El-Gazzar, M. G., Higgins, M., Dinkova-Kostova, A. T. & Shahat, A. A. 2016 In : Journal of Enzyme Inhibition and Medicinal Chemistry. 31, 6, p. 1369-1374 7 p.

    Research output: Contribution to journalArticle

  34. The use of the Rx spin label in orientation measurement on proteins, by EPR

    Stevens, M. A., McKay, J. E., Robinson, J. L. S., El Mkami, H., Smith, G. M. & Norman, D. G. 2016 In : Physical Chemistry Chemical Physics. 18, 8, p. 5799-5806 8 p.

    Research output: Contribution to journalArticle

  35. Specific loss of CatSper function is sufficient to compromise fertilizing capacity of human spermatozoa

    Williams, H. L., Mansell, S., Alasmari, W., Brown, S. G., Wilson, S. M., Sutton, K. A., Miller, M. R., Lishko, P. V., Barratt, C. L. R., Publicover, S. J. & Martins da Silva, S. Dec 2015 In : Human Reproduction. 30, 12, p. 2737-2746 10 p.

    Research output: Contribution to journalArticle

  36. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

  37. BRCA1 is required for maintenance of phospho-Chk1 and G2/M arrest during DNA cross-link repair in DT40 cells

    Draga, M., Madgett, E. B., Vandenberg, C. J., du Plessis, D., Kaufmann, A., Werler, P., Chakraborty, P., Lowndes, N. F. & Hiom, K. Nov 2015 In : Molecular and Cellular Biology. 35, 22, p. 3829-3840 12 p.

    Research output: Contribution to journalArticle

  38. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  39. Development of small-molecule Trypanosoma brucei N-myristoyltransferase inhibitors: discovery and optimisation of a novel binding mode

    Spinks, D., Smith, V., Thompson, S., Robinson, D. A., Luksch, T., Smith, A., Torrie, L. S., McElroy, S., Stojanovski, L., Norval, S., Collie, I. T., Hallyburton, I., Rao, B., Brand, S., Brenk, R., Frearson, J. A., Read, K. D., Wyatt, P. G. & Gilbert, I. H. Nov 2015 In : ChemMedChem. 10, 11, p. 1821-1836 16 p.

    Research output: Contribution to journalArticle

  40. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T. & Hayes, J. D. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 108-146 39 p.

    Research output: Contribution to journalArticle

  41. The emerging role of Nrf2 in mitochondrial function

    Dinkova-Kostova, A. T. & Abramov, A. Y. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 179-188 10 p.

    Research output: Contribution to journalArticle

  42. Trends in socio-economic inequalities in the Scottish diet: 2001-2009

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. Nov 2015 In : Public Health Nutrition. 18, 16, p. 2970-2980 11 p.

    Research output: Contribution to journalArticle

  43. Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

    Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Smith, A-D., Urquhart, G., Bielawski, J., Finnegan, M. & Petty, R. 22 Oct 2015 In : BMC Cancer. 15, 1, 14 p., 762

    Research output: Contribution to journalArticle

  44. Epidermal Growth Factor (EGFR) copy number aberrations in esophageal and gastro-esophageal junctional carcinoma

    Dahle-Smith, Å., Stevenson, D., Massie, D., Murray, G. I., Dutton, S. J., Roberts, C., Ferry, D., Osborne, A., Clark, C., Petty, R. D. & Miedzybrodzka, Z. 17 Oct 2015 In : Molecular Cytogenetics. 8, 9 p., 78

    Research output: Contribution to journalArticle

  45. APOBEC3B-mediated cytidine deamination is required for estrogen receptor action in breast cancer

    Periyasamy, M., Patel, H., Lai, C-F., Nguyen, V. T. M., Nevedomskaya, E., Harrod, A., Russell, R., Remenyi, J., Ochocka, A. M., Thomas, R. S., Fuller-Pace, F., Győrffy, B., Caldas, C., Navaratnam, N., Carroll, J. S., Zwart, W., Coombes, R. C., Magnani, L., Buluwela, L. & Ali, S. 6 Oct 2015 In : Cell Reports. 13, 1, p. 108-121 14 p.

    Research output: Contribution to journalArticle

  46. FLCN and AMPK confer resistance to hyperosmotic stress via remodeling of glycogen stores

    Possik, E., Ajisebutu, A., Manteghi, S., Gingras, M-C., Vijayaraghavan, T., Flamand, M., Coull, B., Schmeisser, K., Duchaine, T., van Steensel, M., Hall, D. H. & Pause, A. 6 Oct 2015 In : PLoS Genetics. 11, 10, 18 p., e1005520

    Research output: Contribution to journalArticle

  47. Mice lacking beta2-integrin function remain glucose tolerant in spite of insulin resistance, neutrophil infiltration and inflammation

    Meakin, P. J., Morrison, V. L., Sneddon, C. C., Savinko, T., Uotila, L., Jalicy, S. M., Gabriel, J. L., Kang, L., Ashford, M. L. J. & Fagerholm, S. C. 25 Sep 2015 In : PLoS ONE. 10, 9, 15 p., e0138872

    Research output: Contribution to journalArticle

  48. Design, synthesis, and evaluation of triazole derivatives that induce Nrf2 dependent gene products and inhibit the Keap1-Nrf2 protein-protein interaction

    Bertrand, H. C., Schaap, M., Baird, L., Georgakopoulos, N. D., Fowkes, A., Thiollier, C., Kachi, H., Dinkova-Kostova, A. T. & Wells, G. 24 Sep 2015 In : Journal of Medicinal Chemistry. 58, 18, p. 7186-7194 9 p.

    Research output: Contribution to journalArticle

  49. Lysyl hydroxylase 3 localizes to epidermal basement membrane and Is reduced in patients with Recessive Dystrophic Epidermolysis Bullosa

    Watt, S. A., Dayal, J. H. S., Wright, S., Riddle, M., Pourreyron, C., McMillan, J. R., Kimble, R. M., Prisco, M., Gartner, U., Warbrick, E., McLean, W. H. I., Leigh, I. M., McGrath, J. A., Salas-Alanis, J. C., Tolar, J. & South, A. P. 18 Sep 2015 In : PLoS ONE. 10, 9, 15 p., e0137639

    Research output: Contribution to journalArticle

  50. A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial

    Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S. 2 Sep 2015 In : Trials. 16, 12 p., 390

    Research output: Contribution to journalArticle

  51. Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes

    Hobley, L., Harkins, C., MacPhee, C. E. & Stanley-Wall, N. R. 1 Sep 2015 In : FEMS Microbiology Reviews. 39, 5, p. 649-669 21 p.

    Research output: Contribution to journalArticle

  52. Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms

    Mowat, C., Digby, J., Strachan, J. A., Wilson, R., Carey, F. A., Fraser, C. G. & Steele, R. J. C. Sep 2015 In : Gut. 65, 9, p. 1463-1469 8 p.

    Research output: Contribution to journalArticle

  53. Is photodynamic diagnostic flexible ureterorenoscopy suitable for a patient presenting with chronic actinic dermatitis?

    Valentine, R., Kata, S., Ibbotson, S., Nabi, G. & Moseley, H. Sep 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 5, p. 279-281 3 p.

    Research output: Contribution to journalLetter

  54. Novel CARD11 mutations in human cutaneous squamous cell carcinoma lead to aberrant NF-κB regulation

    Watt, S. A., Purdie, K. J., den Breems, N. Y., Dimon, M., Arron, S. T., McHugh, A. T., Xue, D. J., Dayal, J. H. S., Proby, C. M., Harwood, C. A., Leigh, I. M. & South, A. P. Sep 2015 In : American Journal of Pathology. 185, 9, p. 2354-2363 10 p.

    Research output: Contribution to journalArticle

  55. Total levels, localization patterns, and proportions of sperm exhibiting phospholipase C zeta are significantly correlated with fertilization rates after intracytoplasmic sperm injection

    Yelumalai, S., Yeste, M., Jones, C., Amdani, S. N., Kashir, J., Mounce, G., Martins Da Silva, S. J., Barratt, C. L., McVeigh, E. & Coward, K. Sep 2015 In : Fertility and Sterility. 104, 3, p. 561-568.e4 12 p.

    Research output: Contribution to journalArticle

  56. Synthesis of carbohydrate capped silicon nanoparticles and their reduced cytotoxicity, in vivo toxicity, and cellular uptake

    Ahire, J. H., Behray, M., Webster, C. A., Wang, Q., Sherwood, V., Saengkrit, N., Ruktanonchai, U., Woramongkolchai, N. & Chao, Y. 26 Aug 2015 In : Advanced Healthcare Materials. 4, 12, p. 1877-1886 10 p.

    Research output: Contribution to journalArticle

  57. The fanconi anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL

    Miles, J. A., Frost, M. G., Carroll, E., Rowe, M. L., Howard, M. J., Sidhu, A., Chaugule, V. K., Alpi, A. F. & Walden, H. 21 Aug 2015 In : Journal of Biological Chemistry. 290, 34, p. 20995-21006 12 p.

    Research output: Contribution to journalArticle

  58. Selective expression of the MAPK phosphatase Dusp9/MKP-4 in mouse plasmacytoid dendritic cells and regulation of IFNβ production1

    Niedzielska, M., Raffi, F. A. M., Tel, J., Muench, S., Jozefowski, K., Alati, N., Lahl, K., Mages, J., Billmeier, U., Schiemann, M., Appelt, U. K., Wirtz, S., Sparwasser, T., Hochrein, H., Figdor, C. G., Keyse, S. M. & Lang, R. 15 Aug 2015 In : Journal of Immunology. 195, 4, p. 1753-1762 10 p.

    Research output: Contribution to journalArticle

  59. The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression

    Zhang, Y., Li, S., Xiang, Y., Qiu, L., Zhao, H. & Hayes, J. D. 13 Aug 2015 In : Scientific Reports. 5, 30 p., 12983

    Research output: Contribution to journalArticle

  60. Correlation between reversal of DNA methylation and clinical symptoms in psoriatic epidermis following narrow-band UVB phototherapy

    Gu, X., Nylander, E., Coates, P. J., Fahraeus, R. & Nylander, K. Aug 2015 In : Journal of Investigative Dermatology. 135, 8, p. 2077-2083 7 p.

    Research output: Contribution to journalArticle

  61. Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3

    Hayes, J. D., Chowdhry, S., Dinkova-Kostova, A. T. & Sutherland, C. Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 611-620 10 p.

    Research output: Contribution to journalArticle

  62. Identifying the unmet supportive care needs of men living with and beyond prostate cancer: A systematic review

    Paterson, C., Robertson, A., Smith, A. & Nabi, G. Aug 2015 In : European Journal of Oncology Nursing. 19, 4, p. 405-418 14 p.

    Research output: Contribution to journalArticle

  63. Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants

    Agathanggelou, A. , Weston, V. J. , Perry, T. , Davies, N. J. , Skowronska, A. , Payne, D. T. , Fossey, J. S. , Oldreive, C. E. , Wei, W. , Pratt, G. , Parry, H. , Oscier, D. , Coles, S. J. , Hole, P. S. , Darley, R. L. , McMahon, M. , Hayes, J. D. , Moss, P. , Stewart, G. , Taylor, A. M. R. & 1 others Stankovic, T. Aug 2015 In : Haematologica. 100, 8, p. 1076-1085 10 p.

    Research output: Contribution to journalArticle

  64. The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

    O'Connell, M. A. & Hayes, J. D. Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 687-689 3 p.

    Research output: Contribution to journalArticle

  65. The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics

    Dinkova-Kostova, A. T., Baird, L., Holmström, K. M., Meyer, C. J. & Abramov, A. Y. Aug 2015 In : Biochemical Society Transactions. 43, 4, p. 602-610 9 p.

    Research output: Contribution to journalArticle

  66. The psychological impact of a colorectal cancer diagnosis following a negative fecal occult blood test result

    Miles, A., McClements, P. L., Steele, R. J. C., Redeker, C., Sevdalis, N. & Wardle, J. 24 Jul 2015 In : Cancer Epidemiology, Biomarkers & Prevention. 24, 7, p. 1032-1038 7 p.

    Research output: Contribution to journalArticle

  67. Regulation of the p53 response and its relationship to cancer

    Meek, D. W. 23 Jul 2015 In : Biochemical Journal. 469, 3, p. 325-346 22 p.

    Research output: Contribution to journalArticle

  68. Time to stand up and make a difference

    Anderson, A. S. & Steele, R. J. C. 8 Jul 2015 In : BMJ. 351, 1 p., h3141

    Research output: Contribution to journalArticle

  69. Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

    Rog-Zielinska, E. A., Craig, M. A., Manning, J. R., Richardson, R. V., Gowans, G. J., Dunbar, D. R., Gharbi, K., Kenyon, C. J., Holmes, M. C., Hardie, D. G., Smith, G. L. & Chapman, K. E. 1 Jul 2015 In : Cell Death & Differentiation. 22, 7, p. 1106-1116 11 p.

    Research output: Contribution to journalArticle

  70. New insights into the role of histone deacetylases as coactivators of inflammatory gene expression

    Schmitz, M. L. & de la Vega, L. 1 Jul 2015 In : Antioxidants & Redox Signaling. 23, 1, p. 85-98 14 p.

    Research output: Contribution to journalArticle

  71. Calculation of limits for significant bidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Jul 2015 In : Annals of Clinical Biochemistry. 52, 4, p. 434-440 7 p.

    Research output: Contribution to journalArticle

  72. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., Macleod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & on behalf of the BeWEL team Jul 2015 In : Colorectal Disease. 17, 7, p. 589-594 6 p.

    Research output: Contribution to journalArticle

  73. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. Jul 2015 In : Journal of Investigative Dermatology. 135, 7, p. 1919-1921 3 p.

    Research output: Contribution to journalLetter

  74. Motion estimation-based image enhancement in ultrasound imaging

    Morin, R., Basarab, A., Bidon, S. & Kouamé, D. Jul 2015 In : Ultrasonics. 60, p. 19-26 8 p.

    Research output: Contribution to journalArticle

  75. Prime mover or fellow traveller: 25-hydroxy vitamin D’s seasonal variation, cardiovascular disease and death in the Scottish Heart Health Extended Cohort (SHHEC)

    Tunstall-Pedoe, H., Woodward, M., Hughes, M., Anderson, A., Kennedy, G., Belch, J., Kuulasmaa, K. & MORGAM Investigators 21 Jun 2015 In : International Journal of Epidemiology. 44, 5, p. 1602-1612 11 p.

    Research output: Contribution to journalArticle

  76. New monocyclic, bicyclic, and tricyclic ethynylcyanodienones as activators of the Keap1/Nrf2/ARE pathway and inhibitors of inducible nitric oxide synthase

    Li, W., Zheng, S., Higgins, M., Morra, R. P., Mendis, A. T., Chien, C-W., Ojima, I., Mierke, D. F., Dinkova-Kostova, A. T. & Honda, T. 11 Jun 2015 In : Journal of Medicinal Chemistry. 58, 11, p. 4738-4748 11 p.

    Research output: Contribution to journalArticle

  77. Multi-scale analysis of the surface morphology of colorectal polyps from optical tomography

    Zhang, J., Zhang, J. G., Coats, M., Li, W., Carey, F. A. & McKenna, S. J. 3 Jun 2015 In : Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. 5, 5, p. 318-328 11 p.

    Research output: Contribution to journalArticle

  78. Corneal tissue interactions of a new 345 nm ultraviolet femtosecond laser

    Hammer, C. M., Petsch, C., Klenke, J., Skerl, K., Paulsen, F., Kruse, F. E., Seiler, T. & Menzel-Severing, J. Jun 2015 In : Journal of Cataract and Refractive Surgery. 41, 6, p. 1279-1288 10 p.

    Research output: Contribution to journalArticle

  79. Individual variability analysis of fluorescence parameters measured in skin with different levels of nutritive blood flow

    Dunaev, A. V., Dremin, V. V., Zherebtsov, E. A., Rafailov, I. E., Litvinova, K. S., Palmer, S. G., Stewart, N. A., Sokolovski, S. G. & Rafailov, E. U. Jun 2015 In : Medical Engineering & Physics. 37, 6, p. 574-583 10 p.

    Research output: Contribution to journalArticle

  80. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    Knatko, E. V., Ibbotson, S. H., Zhang, Y., Higgins, M., Fahey, J. W., Talalay, P., Dawe, R. S., Ferguson, J., Huang, J. T-J., Clarke, R., Zheng, S., Saito, A., Kalra, S., Benedict, A. L., Honda, T., Proby, C. M. & Dinkova-Kostova, A. T. Jun 2015 In : Cancer Prevention Research. 8, 6, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  81. Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

    McGarry, D. J., Chen, W., Chakravarty, P., Lamont, D. L., Wolf, C. R. & Henderson, C. J. Jun 2015 In : Biochemical Journal. 469, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  82. Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma

    Boldrup, L., Coates, P. J., Laurell, G., Wilms, T., Fahraeus, R. & Nylander, K. 26 May 2015 In : British Journal of Cancer. 112, 11, p. 1760-1765 6 p.

    Research output: Contribution to journalArticle

  83. MAGE-A cancer/testis antigens inhibit MDM2 ubiquitylation function and promote increased levels of MDM4

    Marcar, L., Ihrig, B., Hourihan, J., Bray, S. E., Quinlan, P. R., Jordan, L. B., Thompson, A. M., Hupp, T. R. & Meek, D. W. 22 May 2015 In : PLoS ONE. 10, 5, 19 p., e0127713

    Research output: Contribution to journalArticle

  84. Monte Carlo modelling of daylight activated photodynamic therapy

    Campbell, C. L., Wood, K., Valentine, R. M., Brown, C. T. A. & Moseley, H. 21 May 2015 In : Physics in Medicine and Biology. 60, 10, p. 4059-4073 15 p.

    Research output: Contribution to journalArticle

  85. Fc receptors in mucosal immunology

    van Egmond, M., Bakema, J. E. & Woof, J. M. 15 May 2015 Mucosal immunology: Fourth edition. Mestecky, J., Strober, W., Russell, M. W., Kelsall, B. L., Cheroutre, H. & Lambrecht, B. N. (eds.). 4th ed. London: Academic Press, Vol. 1, p. 409-428 20 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  86. Mucosal immunoglobulins

    Woof, J. M. & Mestecky, J. 15 May 2015 Mucosal Immunology: Fourth edition. Mestecky, J., Strober, W., Russell, M. W., Kelsall, B. L., Cheroutre, H. & Lambrecht, B. N. (eds.). 4th ed. London: Academic Press, Vol. 1, p. 287-324 38 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  87. Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

    Wongpaiboonwattana, W. & Stavridis, M. P. 14 May 2015 In : JoVE: Journal of Visualized Experiments. 99, e52823

    Research output: Contribution to journalArticle

  88. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

    Bell, K. F. S., Al-Mubarak, B., Martel, M. A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., Bilican, B., Chowdhry, S., Meakin, P. J., Ashford, M. L. J., Wyllie, D. J. A., Scannevin, R. H., Chandran, S., Hayes, J. D. & Hardingham, G. E. 13 May 2015 In : Nature Communications. 6, 15 p., 7066

    Research output: Contribution to journalArticle

  89. MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma

    Olasz, E. B., Seline, L. N., Schock, A. M., Duncan, N. E., Lopez, A., Lazar, J., Flister, M. J., Lu, Y., Liu, P., Sokumbi, O., Harwood, C. A., Proby, C. M., Neuburg, M. & Lazarova, Z. 4 May 2015 In : PLoS ONE. 10, 5, p. 1-16 16 p., e0125412

    Research output: Contribution to journalArticle

  90. A quantitative assessment of ultraviolet radiation transmission through compression socks

    Valentine, R. & Moseley, H. May 2015 In : British Journal of Dermatology. 172, 5, p. 1445-1447 3 p.

    Research output: Contribution to journalLetter

  91. Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris)

    Moffat, C., Pacheco, J. G., Sharp, S., Samson, A. J., Bollan, K. A., Huang, J., Buckland, S. T. & Connolly, C. N. May 2015 In : FASEB Journal. 29, 5, p. 2112-2119 8 p.

    Research output: Contribution to journalArticle

  92. Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

    Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

    Research output: Contribution to journalArticle

  93. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

  94. Preliminary validation of thiel embalmed cadavers for laparoscopic radical nephrectomy

    Rai, B. P., Stolzenburg, J. U., Healy, S., Tang, B., Jones, P., Sweeney, C., Somani, B. K., Biyani, C. S. & Nabi, G. May 2015 In : Journal of Endourology. 29, 5, p. 595-603 9 p.

    Research output: Contribution to journalArticle

  95. Quantitative urinary proteomics using stable isotope labelling by peptide dimethylation in patients with prostate cancer

    Li, C., Zang, T., Wrobel, K., Huang, J. T. J. & Nabi, G. May 2015 In : Analytical and Bioanalytical Chemistry. 407, 12, p. 3393-3404 12 p.

    Research output: Contribution to journalArticle

  96. The 1999 Stockholm Consensus Conference on quality specifications in laboratory medicine

    Fraser, C. G. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 837-840 4 p.

    Research output: Contribution to journalArticle

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