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  1. Mutations in GRHL2 result in an autosomal-recessive ectodermal dysplasia syndrome

    Petrof, G., Nanda, A., Howden, J., Takeichi, T., McMillan, J. R., Aristodemou, S., Ozoemena, L., Liu, L., South, A. P., Pourreyron, C., Dafou, D., Proudfoot, L. E., Al-Ajmi, H., Akiyama, M., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A. 4 Sep 2014 In : American Journal of Human Genetics. 95, 3, p. 308-314 7 p.

    Research output: Contribution to journalArticle

  2. Leporid immunoglobulin G shows evidence of strong selective pressure on the hinge and CH3 domains

    Pinheiro, A., Woof, J. M., Almeida, T., Abrantes, J., Alves, P. C., Gortázar, C. & Esteves, P. J. Sep 2014 In : Open Biology. 4, 9 p.140088

    Research output: Contribution to journalArticle

  3. Malignancy-associated hyperamylasaemia

    Srivastava, R., Murphy, M. J. & Fraser, C. G. Sep 2014 In : Annals of Clinical Biochemistry. 51, 5, p. 619 1 p.

    Research output: Contribution to journalLetter

  4. Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

    Marcel, V., Fernandes, K., Terrier, O., Lane, D. P. & Bourdon, J-C. Sep 2014 In : Cell Death & Differentiation. 21, p. 1377-1387 11 p.

    Research output: Contribution to journalArticle

  5. The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

    Salmond, R. J., Brownlie, R. J., Morrison, V. L. & Zamoyska, R. Sep 2014 In : Nature Immunology. 15, 9, p. 875-883 8 p.

    Research output: Contribution to journalArticle

  6. BRCA1 is a histone-H2A-specific ubiquitin ligase

    Kalb, R., Mallery, D. L., Larkin, C., Huang, J. T. J. & Hiom, K. 21 Aug 2014 In : Cell Reports. 8, 4, p. 999-1005 7 p.

    Research output: Contribution to journalArticle

  7. Accuracy of non-operative identification of the sentinel lymph node using combined gamma and ultrasound scanning

    Whelehan, P., Vinnicombe, S. J., Brown, D. C., McLean, D. & Evans, A. Aug 2014 In : Clinical Radiology. 69, 8, p. 849-852 4 p.

    Research output: Contribution to journalArticle

  8. An investigation into the MMP1 gene promoter region polymorphism - 1607 2G with recessive dystrophic epidermolysis bullosa disease severity in northeastern Mexican patients

    Garza-Gómez, J., Cerda-Flores, R. M., Gómez-Flores, M., Salas-Alanís, J. C., Ocampo-Candiani, J., Martínez-Garza, L. E., South, A. P. & Gallardo-Blanco, H. L. Aug 2014 In : International Journal of Dermatology. 53, 8, p. 985-990 6 p.

    Research output: Contribution to journalArticle

  9. Chemical tuning enhances both potency toward Nrf2 and in vitro therapeutic index of triterpenoids

    Copple, I. M., Shelton, L. M., Walsh, J., Kratschmar, D. V., Lister, A., Odermatt, A., Goldring, C. E., Dinkova-Kostova, A. T., Honda, T. & Park, B. K. Aug 2014 In : Toxicological Sciences. 140, 2, p. 462-469 8 p.

    Research output: Contribution to journalArticle

  10. Evidence for aldosterone-dependent growth of renal cell carcinoma

    King, S., Bray, S., Galbraith, S., Christie, L. & Fleming, S. Aug 2014 In : International Journal of Experimental Pathology. 95, 4, p. 244-250 7 p.

    Research output: Contribution to journalArticle

  11. Therapeutic targeting of integrin αvβ6 in breast cancer

    Moore, K. M. , Thomas, G. J. , Duffy, S. W. , Warwick, J. , Gabe, R. , Chou, P. , Ellis, I. O. , Green, A. R. , Haider, S. , Brouilette, K. , Saha, A. , Vallath, S. , Bowen, R. , Chelala, C. , Eccles, D. , Tapper, W. J. , Thompson, A. M. , Quinlan, P. , Jordan, L. , Gillett, C. & 8 others Brentnall, A., Violette, S., Weinreb, P. H., Kendrew, J., Barry, S. T., Hart, I. R., Jones, J. L. & Marshall, J. F. Aug 2014 In : Journal of the National Cancer Institute. 106, 8, 14 p.dju169

    Research output: Contribution to journalArticle

  12. Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II

    Magnani, F., Pappas, C. G., Crook, T., Magafa, V., Cordopatis, P., Ishiguro, S., Ohta, N., Selent, J., Bosnyak, S., Jones, E. S., Gerothanassis, I. P., Tamura, M., Widdop, R. E. & Tzakos, A. G. 18 Jul 2014 In : ACS Chemical Biology. 9, 7, p. 1420-1425 6 p.

    Research output: Contribution to journalArticle

  13. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  14. Energy density of the Scottish diet estimated from food purchase data: relationship with socio-economic position and dietary targets

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. 14 Jul 2014 In : British Journal of Nutrition. 112, 1, p. 80-88 9 p.

    Research output: Contribution to journalArticle

  15. Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast

    Thomas, J., Hanby, A., Pinder, S. E., Ball, G., Lawrence, G., Maxwell, A., Wallis, M., Evans, A., Dobson, H., Clements, K., Thompson, A. & Sloane Project Steering Group Jul 2014 In : European Journal of Cancer. 50, 11, p. 1880-1890 11 p.

    Research output: Contribution to journalArticle

  16. Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

    Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J. Jul 2014 In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

    Research output: Contribution to journalArticle

  17. Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status

    Bouchalova, P., Nenutil, R., Muller, P., Hrstka, R., Appleyard, M. V., Murray, K., Jordan, L. B., Purdie, C. A., Quinlan, P., Thompson, A. M., Vojtesek, B. & Coates, P. J. Jul 2014 In : Journal of Pathology. 233, 3, p. 238-246 9 p.

    Research output: Contribution to journalArticle

  18. Comparative cancer survival in European countries

    Munro, A. J. Jun 2014 In : British Medical Bulletin. 110, 1, p. 5-22 18 p.

    Research output: Contribution to journalArticle

  19. Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization: a solution for practical application

    Li, C., Guan, G., Zhang, F., Nabi, G., Wang, R. K. & Huang, Z. 1 May 2014 In : Biomedical Optics Express. 5, 5, p. 1403-1418 16 p.

    Research output: Contribution to journalArticle

  20. Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue

    Rentoft, M., Coates, P. J., Loljung, L., Wilms, T., Laurell, G. & Nylander, K. May 2014 In : Tumor Biology. 35, 5, p. 4191-4198 8 p.

    Research output: Contribution to journalArticle

  21. Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels

    Mansell, S. A., Publicover, S. J., Barratt, C. L. R. & Wilson, S. M. May 2014 In : Molecular Human Reproduction. 20, 5, p. 392-408 17 p.

    Research output: Contribution to journalArticle

  22. E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin

    MacKay, C., Carroll, E., Ibrahim, A. F. M., Garg, A., Inman, G. J., Hay, R. T. & Alpi, A. F. 15 Apr 2014 In : Cancer Research. 74, 8, p. 2246-2257 12 p.

    Research output: Contribution to journalArticle

  23. Lack of correlation of stem cell markers in breast cancer stem cells

    Liu, Y., Nenutil, R., Appleyard, M. V., Murray, K., Boylan, M., Thompson, A. M. & Coates, P. J. 15 Apr 2014 In : British Journal of Cancer. 110, 8, p. 2063-2071 9 p.

    Research output: Contribution to journalArticle

  24. Cytochrome b and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

    Stiborová, M., Moserová, M., Černá, V., Indra, R., Dračínský, M., Šulc, M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H., Frei, E. & Arlt, V. M. 6 Apr 2014 In : Toxicology. 318, 1, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  25. A gender-sensitised weight loss and healthy living programme for overweight and obese men delivered by Scottish Premier League football clubs (FFIT): a pragmatic randomised controlled trial

    Hunt, K., Wyke, S., Gray, C. M., Anderson, A. S., Brady, A., Bunn, C., Donnan, P. T., Fenwick, E., Grieve, E., Lieshman, J., Miller, E., Mutrie, N., Rauchhaus, P., White, A. & Treweek, S. 5 Apr 2014 In : Lancet. 383, 9924, p. 1211-1221 11 p.

    Research output: Contribution to journalArticle

  26. Antibiotic treatments and microbes in the gut

    Macfarlane, S. Apr 2014 In : Environmental Microbiology. 16, 4, p. 919-924 6 p.

    Research output: Contribution to journalArticle

  27. Epigenetic profiles as defined signatures of xenobiotic exposure

    Thomson, J. P., Moggs, J. G., Wolf, C. R. & Meehan, R. R. Apr 2014 In : Mutation Research: Genetic Toxicology and Environmental Mutagenesis. 764-765, p. 3-9 7 p.

    Research output: Contribution to journalArticle

  28. What are the characteristics of breast cancers misclassified as benign by quantitative ultrasound shear wave elastography?

    Vinnicombe, S. J., Whelehan, P., Thomson, K., McLean, D., Purdie, C. A., Jordan, L. B., Hubbard, S. & Evans, A. J. Apr 2014 In : European Radiology. 24, 4, p. 921-926 6 p.

    Research output: Contribution to journalArticle

  29. Biopsy confirmation of metastatic sites in breast cancer patients: clinical impact and future perspectives

    Criscitiello, C., André, F., Thompson, A. M., De Laurentiis, M., Esposito, A., Gelao, L., Fumagalli, L., Locatelli, M., Minchella, I., Orsi, F., Goldhirsch, A. & Curigliano, G. 21 Mar 2014 In : Breast Cancer Research. 16, 2, 205

    Research output: Contribution to journalArticle

  30. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  31. BPAG1-e restricts keratinocyte migration through control of adhesion stability

    Michael, M., Begum, R., Fong, K., Pourreyrone, C., South, A. P., McGrath, J. A. & Parsons, M. Mar 2014 In : Journal of Investigative Dermatology. 134, 3, p. 773-782 10 p.

    Research output: Contribution to journalArticle

  32. Nrf2 affects the efficiency of mitochondrial fatty acid oxidation

    Ludtmann, M. H. R., Angelova, P. R., Zhang, Y., Abramov, A. Y. & Dinkova-Kostova, A. T. 1 Feb 2014 In : Biochemical Journal. 457, 3, p. 415-424 10 p.

    Research output: Contribution to journalArticle

  33. Prognostic and therapeutic impact of Argininosuccinate Synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

    Allen, M. D. , Luong, P. , Hudson, C. , Leyton, J. , Delage, B. , Ghazaly, E. , Cutts, R. , Yuan, M. , Syed, N. , Lo Nigro, C. , Lattanzio, L. , Chmielewska-Kassassir, M. , Tomlinson, I. , Roylance, R. , Whitaker, H. C. , Warren, A. Y. , Neal, D. , Frezza, C. , Beltran, L. , Jones, L. J. & 13 others Chelala, C., Wu, B-W., Bomalaski, J. S., Jackson, R. C., Lu, Y-J., Crook, T., Lemoine, N. R., Mather, S., Foster, J., Sosabowski, J., Avril, N., Li, C-F. & Szlosarek, P. W. 1 Feb 2014 In : Cancer Research. 74, 3, p. 896-907 12 p.

    Research output: Contribution to journalArticle

  34. Psychological, surgical, and sociodemographic predictors of pain outcomes after breast cancer surgery: A population-based cohort study

    Bruce, J., Thornton, A. J., Powell, R., Johnston, M., Wells, M., Heys, S. D., Thompson, A. M., Smith, W. C., Chambers, W. A. & Scott, N. W. Feb 2014 In : PAIN. 155, 2, p. 232-243 12 p.

    Research output: Contribution to journalArticle

  35. Results of a Randomized Controlled Trial to promote Physical Activity Behaviours in Mothers with Young Children

    Monteiro, S. M. D. R., Jancey, J., Dhaliwal, S. S., Howat, P. A., Burns, S., Hills, A. P. & Anderson, A. S. Feb 2014 In : Preventive Medicine. 59, p. 12-18 7 p.

    Research output: Contribution to journalArticle

  36. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-a randomised trial

    Vaidya, J. S. , Wenz, F. , Bulsara, M. , Tobias, J. S. , Joseph, D. J. , Keshtgar, M. , Flyger, H. L. , Massarut, S. , Alvarado, M. , Saunders, C. , Eiermann, W. , Metaxas, M. , Sperk, E. , Sütterlin, M. , Brown, D. , Esserman, L. , Roncadin, M. , Thompson, A. , Dewar, J. A. , Holtveg, H. M. R. & 9 others Pigorsch, S., Falzon, M., Harris, E., Matthews, A., Brew-Graves, C., Potyka, I., Corica, T., Williams, N. R. & Baum, M. Feb 2014 In : Lancet. 383, 9917, p. 603-613 11 p.

    Research output: Contribution to journalArticle

  37. Grow₂: The HIF system, energy homeostasis and the cell cycle

    Moniz, S., Biddlestone, J. & Rocha, S. 10 Jan 2014 In : Histology and Histopathology.

    Research output: Contribution to journalArticle

  38. Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation

    Zhang, Y., Dayalan Naidu, S., Samarasinghe, K., Van Hecke, G. C., Pheely, A., Boronina, T. N., Cole, R. N., Benjamin, I. J., Cole, P. A., Ahn, Y-H. & Dinkova-Kostova, A. T. 7 Jan 2014 In : British Journal of Cancer. 110, 1, p. 71-82 12 p.

    Research output: Contribution to journalArticle

  39. A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice

    Henderson, C. J., McLaughlin, L. A., Finn, R. D., Ronseaux, S., Kapelyukh, Y. & Wolf, C. R. Jan 2014 In : Drug Metabolism and Disposition. 42, 1, p. 70-77 8 p.

    Research output: Contribution to journalArticle

  40. Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?

    Evans, A., Rauchhaus, P., Whelehan, P., Thomson, K., Purdie, C. A., Jordan, L. B., Michie, C. O., Thompson, A. & Vinnicombe, S. Jan 2014 In : Breast Cancer Research and Treatment. 143, 1, p. 153-157 5 p.

    Research output: Contribution to journalArticle

  41. Interpretation of EUROCARE-5

    Munro, A. J. Jan 2014 In : Lancet Oncology. 15, 1, p. 2-3 2 p.

    Research output: Contribution to journalComment/debate

  42. Patterns of uptake in a biennial faecal occult blood test screening programme for colorectal cancer

    Steele, R. J. C., McClements, P. L., Libby, G., Carey, F. A. & Fraser, C. . G. Jan 2014 In : Colorectal Disease. 16, 1, p. 28-32 5 p.

    Research output: Contribution to journalArticle

  43. Progression, interobserver agreement, and malignancy rate in complex renal cysts (≥Bosniak category IIF)

    El-Mokadem, I., Budak, M., Pillai, S., Lang, S., Doull, R., Goodman, C. & Nabi, G. Jan 2014 In : Urologic Oncology: Seminars and Original Investigations. 32, 1, p. 24.e21-e27 7 p.

    Research output: Contribution to journalArticle

  44. CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations

    Province, M. A. , Goetz, M. P. , Brauch, H. , Flockhart, D. A. , Hebert, J. M. , Whaley, R. , Suman, V. J. , Schroth, W. , Winter, S. , Zembutsu, H. , Mushiroda, T. , Newman, W. G. , Lee, M-T. M. , Ambrosone, C. B. , Beckmann, M. W. , Choi, J-Y. , Dieudonné, A-S. , Fasching, P. A. , Ferraldeschi, R. , Gong, L. & 34 others Haschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B-W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J-G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N. & Klein, T. E. 2014 In : Clinical Pharmacology & Therapeutics. 95, 2, p. 216-227 12 p.

    Research output: Contribution to journalArticle

  45. 3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: potential candidates for chemoprevention

    Nagle, A. A., Reddy, S. A., Bertrand, H., Tajima, H., Dang, T-M., Wong, S-C., Hayes, J. D., Wells, G. & Chew, E-H. 2014 In : ChemMedChem. 9, 8, p. 1763-1774 12 p.

    Research output: Contribution to journalArticle

  46. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol

    Holt, A-M., Jancey, J., Lee, A. H., Kerr, D. A., Hills, A. P., Anderson, A. S. & Howat, P. A. 2014 In : BMJ Open. 4, 9, p. e005107

    Research output: Contribution to journalArticle

  47. A critical role for beta2 integrins in podosome formation, dynamics and TLR-signaled disassembly in dendritic cells

    Gawden-Bone, C., West, M. A., Morrison, V. L., Edgar, A. J., McMillan, S. J., Dill, B. D., Trost, M., Prescott, A., Fagerholm, S. C. & Watts, C. 2014 In : Journal of Cell Science. 37 p.

    Research output: Contribution to journalArticle

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