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Division of Cancer Research

  1. Motion estimation-based image enhancement in ultrasound imaging

    Morin, R., Basarab, A., Bidon, S. & Kouamé, D. Jul 2015 In : Ultrasonics. 60, p. 19-26 8 p.

    Research output: Contribution to journalArticle

  2. Individual variability analysis of fluorescence parameters measured in skin with different levels of nutritive blood flow

    Dunaev, A. V., Dremin, V. V., Zherebtsov, E. A., Rafailov, I. E., Litvinova, K. S., Palmer, S. G., Stewart, N. A., Sokolovski, S. G. & Rafailov, E. U. Jun 2015 In : Medical Engineering & Physics. 37, 6, p. 574-583 10 p.

    Research output: Contribution to journalArticle

  3. MAGE-A cancer/testis antigens inhibit MDM2 ubiquitylation function and promote increased levels of MDM4

    Marcar, L., Ihrig, B., Hourihan, J., Bray, S. E., Quinlan, P. R., Jordan, L. B., Thompson, A. M., Hupp, T. R. & Meek, D. W. 22 May 2015 In : PLoS ONE. 10, 5, 19 p., e0127713

    Research output: Contribution to journalArticle

  4. Monte Carlo modelling of daylight activated photodynamic therapy

    Campbell, C. L., Wood, K., Valentine, R. M., Brown, C. T. A. & Moseley, H. 21 May 2015 In : Physics in Medicine and Biology. 60, 10, p. 4059-4073 15 p.

    Research output: Contribution to journalArticle

  5. Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

    Wongpaiboonwattana, W. & Stavridis, M. P. 14 May 2015 In : JoVE: Journal of Visualized Experiments. 99, e52823

    Research output: Contribution to journalArticle

  6. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

    Bell, K. F. S., Al-Mubarak, B., Martel, M. A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., Bilican, B., Chowdhry, S., Meakin, P. J., Ashford, M. L. J., Wyllie, D. J. A., Scannevin, R. H., Chandran, S., Hayes, J. D. & Hardingham, G. E. 13 May 2015 In : Nature Communications. 6, 15 p., 7066

    Research output: Contribution to journalArticle

  7. A quantitative assessment of ultraviolet radiation transmission through compression socks

    Valentine, R. & Moseley, H. May 2015 In : British Journal of Dermatology. 172, 5, p. 1445-1447 3 p.

    Research output: Contribution to journalLetter

  8. Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris).

    Moffat, C., Pacheco, J. G., Sharp, S., Samson, A. J., Bollan, K. A., Huang, J., Buckland, S. T. & Connolly, C. N. May 2015 In : FASEB Journal. 29, 5, p. 2112-2119

    Research output: Contribution to journalArticle

  9. Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

    Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

    Research output: Contribution to journalArticle

  10. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

  11. Preliminary validation of thiel embalmed cadavers for laparoscopic radical nephrectomy

    Rai, B. P., Stolzenburg, J. U., Healy, S., Tang, B., Jones, P., Sweeney, C., Somani, B. K., Biyani, C. S. & Nabi, G. May 2015 In : Journal of Endourology. 29, 5, p. 595-603 9 p.

    Research output: Contribution to journalArticle

  12. Quantitative urinary proteomics using stable isotope labelling by peptide dimethylation in patients with prostate cancer

    Li, C., Zang, T., Wrobel, K., Huang, J. T. J. & Nabi, G. May 2015 In : Analytical and Bioanalytical Chemistry. 407, 12, p. 3393-3404 12 p.

    Research output: Contribution to journalArticle

  13. The 1999 Stockholm Consensus Conference on quality specifications in laboratory medicine

    Fraser, C. G. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 837-840 4 p.

    Research output: Contribution to journalArticle

  14. The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site

    Orzol, P., Holcakova, J., Nekulova, M., Nenutil, R., Vojtesek, B. & Coates, P. J. May 2015 In : Histology and Histopathology. 30, 5, p. 503-521 19 p.

    Research output: Contribution to journalArticle

  15. The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

    Woods, J. A., Evans, A., Forbes, P. D., Coates, P. J., Gardner, J., Valentine, R. M., Ibbotson, S. H., Ferguson, J., Fricker, C. & Moseley, H. May 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 3, p. 159-166 8 p.

    Research output: Contribution to journalArticle

  16. MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and-independent mechanisms

    Amankwatia, E. B., Chakravarty, P., Carey, F. A., Weidlich, S., Steele, R. J. C., Munro, A. J., Wolf, C. R. & Smith, G. 28 Apr 2015 In : British Journal of Cancer. 112, 9, p. 1480-1490 11 p.

    Research output: Contribution to journalArticle

  17. Choosing the best method to estimate the energy density of a population using food purchase data

    Wrieden, W. L., Armstrong, J., Anderson, A. S., Sherriff, A. & Barton, K. L. Apr 2015 In : Journal of Human Nutrition and Dietetics. 28, 2, p. 126-134 9 p.

    Research output: Contribution to journalArticle

  18. Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

    Henderson, C. J., McLaughlin, L. A., Scheer, N., Stanley, L. A. & Wolf, C. R. Apr 2015 In : Molecular Pharmacology. 87, 4, p. 733-739 7 p.

    Research output: Contribution to journalArticle

  19. Nrf2 regulates ROS production by mitochondria and NADPH oxidase

    Kovac, S., Angelova, P. R., Holmström, K. M., Zhang, Y., Dinkova-Kostova, A. T. & Abramov, A. Y. Apr 2015 In : Biochimica et Biophysica Acta: General Subjects. 1850, 4, p. 794-801 8 p.

    Research output: Contribution to journalArticle

  20. Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

    Fleming, S. & 44 others Kovac, M., Navas, C., Horswell, S., Salm, M., Bardella, C., Rowan, A., Stares, M., Castro-Giner, F., Fisher, R., de Bruin, E. C., Kovacova, M., Gorman, M., Makino, S., Williams, J., Jaeger, E., Jones, A., Howarth, K., Larkin, J., Pickering, L., Gore, M., Nicol, D. L., Hazell, S., Stamp, G., O'Brien, T., Challacombe, B., Matthews, N., Phillimore, B., Begum, S., Rabinowitz, A., Varela, I., Chandra, A., Horsfield, C., Polson, A., Tran, M., Bhatt, R., Terracciano, L., Eppenberger-Castori, S., Protheroe, A., Maher, E., El Bahrawy, M., Ratcliffe, P., Heinimann, K., Swanton, C. & Tomlinson, I. 19 Mar 2015 In : Nature Communications. 6, 11 p., 6336

    Research output: Contribution to journalArticle

  21. Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins

    Colin, D. J., Hain, K. O., Allan, L. A. & Clarke, P. R. 11 Mar 2015 In : Open Biology. 5, 13 p., 140156

    Research output: Contribution to journalArticle

  22. Detection of urinary bladder cancer cells using redox ratio and double excitation wavelengths autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 1 Mar 2015 In : Biomedical Optics Express. 6, 3, p. 977-986 10 p.

    Research output: Contribution to journalArticle

  23. An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes

    MacLeod, A. K., Fallon, P. G., Sharp, S., Henderson, C. J., Wolf, C. R. & Huang, J. T-J. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 750-760 11 p.

    Research output: Contribution to journalArticle

  24. Biological variation: a still evolving facet of laboratory medicine

    Simundic, A. M., Bartlett, W. A. & Fraser, C. G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 189-190 2 p.

    Research output: Contribution to journalEditorial

  25. Calculation of limits for significant unidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 237-244 8 p.

    Research output: Contribution to journalArticle

  26. Distal nephron neoplasms

    Fleming, S. Mar 2015 In : Seminars in Diagnostic Pathology. 32, 2, p. 114-123 10 p.

    Research output: Contribution to journalArticle

  27. Laser-induced autofluorescence spectroscopy: Can it be of importance in detection of bladder lesions?

    Aboumarzouk, O., Valentine, R., Buist, R., Ahmad, S., Nabi, G., Eljamel, S., Moseley, H. & Kata, S. G. Mar 2015 In : Photodiagnosis and Photodynamic Therapy. 12, 1, p. 76-83 8 p.

    Research output: Contribution to journalArticle

  28. Thiel Embalming Method for Cadaver Preservation: A Review of New Training Model for Urologic Skills Training

    Healy, S. E., Rai, B. P., Biyani, C. S., Eisma, R., Soames, R. W. & Nabi, G. Mar 2015 In : Urology. 85, 3, p. 499-504 6 p.

    Research output: Contribution to journalArticle

  29. Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability

    Henderson, C. J., McLaughlin, L. A., Osuna-Cabello, M., Taylor, M., Gilbert, I., McLaren, A. W. & Wolf, C. R. 1 Feb 2015 In : Biochemical Journal. 465, 3, p. 479-488 10 p.

    Research output: Contribution to journalArticle

  30. Detection and characterisation of biopsy tissue using quantitative optical coherence elastography (OCE) in men with suspected prostate cancer

    Li, C., Guan, G., Ling, Y., Hsu, Y-T., Song, S., Huang, J. T-J., Lang, S., Wang, R. K., Huang, Z. & Nabi, G. 1 Feb 2015 In : Cancer Letters. 357, 1, p. 121-128 8 p.

    Research output: Contribution to journalArticle

  31. Insight from the air-skin interface

    O'Shaughnessy, R. F. L. & Brown, S. J. Feb 2015 In : Journal of Investigative Dermatology. 135, 2, p. 331-333 3 p.

    Research output: Contribution to journalComment/debate

  32. Oxidation reduction is a key process for successful treatment of psoriasis by narrow-band UVB phototherapy

    Gu, X., Nylander, E., Coates, P. J. & Nylander, K. Feb 2015 In : Acta Dermato-Venereologica. 95, 2, p. 140-146 7 p.

    Research output: Contribution to journalArticle

  33. Terms and symbols used in studies on biological variation: the need for harmonization

    Simundic, A. M., Kackov, S., Miler, M., Fraser, C. G. & Petersen, P. H. Feb 2015 In : Clinical Chemistry. 61, 2, p. 438-439 2 p.

    Research output: Contribution to journalLetter

  34. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration

    Pajaud, J., Ribault, C., Ben Mosbah, I., Rauch, C., Henderson, C., Bellaud, P., Aninat, C., Loyer, P., Morel, F. & Corlu, A. 15 Jan 2015 In : Cell Death and Disease. 6, 13 p., e1598

    Research output: Contribution to journalArticle

  35. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

    Brown, S. J. & 38 others Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I., Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S. & Cordell, H. J. 8 Jan 2015 In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticle

  36. An updated Asia Pacific Consensus Recommendations on colorectal cancer screening

    Sung, J. J. Y., Ng, S. C., Chan, F. K. L., Chiu, H. M., Kim, H. S., Matsuda, T., Ng, S. S. M., Lau, J. Y. W., Zheng, S., Adler, S., Reddy, N., Yeoh, K. G., Tsoi, K. K. F., Ching, J. Y. L., Kuipers, E. J., Rabeneck, L., Young, G. P., Steele, R. J., Lieberman, D. & Goh, K. L. Jan 2015 In : Gut. 64, 1, p. 121-132 12 p.

    Research output: Contribution to journalArticle

  37. Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

    Brough, H. A., Liu, A. H., Sicherer, S., Makinson, K., Douiri, A., Brown, S. J., Stephens, A. C., McLean, W. H. I., Turcanu, V., Wood, R. A., Jones, S. M., Burks, W., Dawson, P., Stablein, D., Sampson, H. & Lack, G. Jan 2015 In : Journal of Allergy and Clinical Immunology. 135, 1, p. 164-170.e4 11 p.

    Research output: Contribution to journalArticle

  38. Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

    Dayalan Naidu, S., Kostov, R. V. & Dinkova-Kostova, A. T. Jan 2015 In : Trends in Pharmacological Sciences. 36, 1, p. 6-14 9 p.

    Research output: Contribution to journalArticle

  39. Viruses and disease: emerging concepts for prevention, diagnosis and treatment

    Herrington, C. S., Coates, P. J. & Duprex, W. P. Jan 2015 In : Journal of Pathology. 235, 2, p. 149-152 4 p.

    Research output: Contribution to journalArticle

  40. A novel excitation-emission wavelength model to facilitate the diagnosis of urinary bladder diseases

    Rafailov, I., Palmer, S., Litvinova, K., Dremin, V., Dunaev, A. & Nabi, G. 2015 Photonic Therapeutics and Diagnostics XI. Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Nuttal, A., Richter, C-P., Skala, M. C., Dewhirst, M. W., Tearney, G. J., Gregory, K. W., Marcu, L., Mandelis, A. & Morris, M. D. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93030W. (Proceedings of SPIE; vol. 9303)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  41. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., MacLeod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & The BeWEL team. 2015 In : Colorectal Disease. 14 p.

    Research output: Contribution to journalArticle

  42. Discrimination of healthy and cancer cells of the bladder by metabolic state, based on autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 2015 Photonic Therapeutics and Diagnostics XI. Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Nuttal, A., Richter, C-P., Skala, M. C., Dewhirst, M. W., Tearney, G. J., Gregory, K. W., Marcu, L. & Mandelis, A. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93030T. (Proceedings of SPIE; vol. 9303)(Progress In Biomedical Optics And Imaging; vol. 16, no. 1)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  43. Kidney biopsy findings in primary Sjogren syndrome

    Kidder, D., Rutherford, E., Kipgen, D., Fleming, S., Geddes, C. & Stewart, G. A. 2015 In : Nephrology Dialysis Transplantation. 7 p.

    Research output: Contribution to journalArticle

  44. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. 2015 In : Journal of Investigative Dermatology. 3 p.

    Research output: Contribution to journalLetter

  45. Mitotic kinases and phosphatases cooperate to shape the right response

    Vallardi, G. & Saurin, A. T. 2015 In : Cell Cycle. 14, 6, p. 795-796 2 p.

    Research output: Contribution to journalEditorial

  46. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    Knatko, E. V., Ibbotson, S. H., Zhang, Y., Higgins, M., Fahey, J. W., Talalay, P., Dawa, R., Ferguson, J., Huang, J. T-J., Clarke, R., Zheng, S., Saito, A., Kalra, S., Benedict, A. L., Honda, T., Proby, C. M. & Dinkova-Kostova, A. T. 2015 In : Cancer Prevention Research.

    Research output: Contribution to journalArticle

  47. Optical coherence elastography (OCE) as a method for identifying benign and malignant prostate biopsies

    Li, C., Guan, G., Ling, Y., Lang, S., Wang, R. K., Huang, Z. & Nabi, G. 2015 Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIX. Fujimoto, J. G., Izatt, J. A. & Tuchin, V. V. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93122S. (Proceedings of SPIE; vol. 9312)(Progress in Biomedical Optics and Imaging; vol. 16, no. 10)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

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