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  1. Evidence that Cytochrome b5 and Cytochrome b5 Reductase Can Act as Sole Electron Donors to the Hepatic Cytochrome P450 System

    Henderson, C. J., McLaughlin, L. A. & Wolf, C. R. Jun-2013 In : Molecular Pharmacology. 83, 6, p. 1209-1217, 9 p.

    Research output: Contribution to journal › Article

  2. Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality?

    Blackett, K. L., Siddhi, S. S., Cleary, S., Steed, H., Miller, M. H., Macfarlane, S., Macfarlane, G. T. & Dillon, J. F. Jun-2013 In : Alimentary Pharmacology & Therapeutics. 37, 11, p. 1084-1092, 9 p.

    Research output: Contribution to journal › Article

  3. Effects of antibiotics on bacterial species composition and metabolic activities in chemostats containing defined populations of human gut microorganisms

    Newton, D. F., Macfarlane, S. & Macfarlane, G. T. May-2013 In : Antimicrobial Agents and Chemotherapy. 57, 5, p. 2016-2025, 10 p.

    Research output: Contribution to journal › Article

  4. Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a

    Terrier, O., Textoris, J., Carron, C., Marcel, V., Bourdon, J-C. & Rosa-Calatrava, M. May-2013 In : Journal of General Virology. 94, 5, p. 985-95, 11 p.

    Research output: Contribution to journal › Article

  5. Laparoscopic Surgical Skills are Significantly Improved by the Use of a Portable Laparoscopic Simulator: Results of a Randomized Controlled Trial

    Johnston, T. J., Tang, B., Alijani, A., Tait, I., Steele, R. J., Ker, J., Nabi, G. & Surgical Simulation Group at the University of Dundee May-2013 In : World Journal of Surgery. 37, 5, p. 957-964, 8 p.

    Research output: Contribution to journal › Article

  6. Improved sperm function / activity

    Barratt, C. & Wyatt, P. 18-Apr-2013 WO2013054111 A1

    Research output: Patent

  7. p53 Protein Isoforms: Key Regulators in the Front Line of Pathogen Infections?

    Terrier, O., Bourdon, J-C. & Rosa-Calatrava, M. 4-Apr-2013 In : PLoS Pathogens. 9, 4, p. e1003246

    Research output: Contribution to journal › Article

  8. Palliative care for patients with gastrointestinal cancer dying under surgical care: a case for acute palliative care units?

    Young, J. A., Waugh, L., McPhillips, G., Levack, P. & Thompson, A. M. Apr-2013 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 11, 2, p. 72-75, 4 p.

    Research output: Contribution to journal › Article

  9. The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

    Alasmari, W., Barratt, C. L. R., Publicover, S. J., Whalley, K. M., Foster, E., Kay, V., Martins Da Silva, S. & Oxenham, S. K. Apr-2013 In : Human Reproduction. 28, 4, p. 866-876, 11 p.

    Research output: Contribution to journal › Article

  10. What should it take to describe a substance or product as 'sperm-safe'

    Mortimer, D., Barratt, C. L. R., Björndahl, L., de Jager, C., Jequier, A. M. & Muller, C. H. Apr-2013 In : Human Reproduction Update. 19, SUPPL1, p. i1-i45, 45 p.

    Research output: Contribution to journal › Article

  11. Workplace dietary improvement initiatives ought not to be discouraged by modest returns from low-intensity interventions

    Mooney, J. D., Frank, J. & Anderson, A. S. Apr-2013 In : European Journal of Public Health. 23, 2, p. 193-194, 2 p.

    Research output: Contribution to journal › Article

  12. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells

    Baird, L. & Dinkova-Kostova, A. T. 29-Mar-2013 In : Biochemical and Biophysical Research Communications. 433, 1, p. 58-65, 8 p.

    Research output: Contribution to journal › Article

  13. Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b beta2-integrin-dependent signalling

    McMillan, S. J., Sharma, R. S., McKenzie, E. J., Richards, H. E., Zhang, J., Prescott, A. & Crocker, P. R. 14-Mar-2013 In : Blood. 121, 11, p. 2084-2094, 11 p.

    Research output: Contribution to journal › Article

  14. Obesity and lifestyle advice in colorectal cancer survivors - How well are clinicians prepared?

    Anderson, A. S., Caswell, S., Wells, M. & Steele, R. J. C. 9-Mar-2013 In : Colorectal Disease. 15 p.

    Research output: Contribution to journal › Article

  15. Transrectal quantitative shear wave elastography in the detection and characterisation of prostate cancer

    Ahmad, S., Cao, R., Varghese, T., Bidaut, L. & Nabi, G. Mar-2013 In : Surgical Endoscopy. p. 1-8, 8 p.

    Research output: Contribution to journal › Article

  16. Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality

    McCowan, C., Munro, A. J., Donnan, P. T. & Steele, R. J. C. Mar-2013 In : European Journal of Cancer. 49, 5, p. 1049-1057, 9 p.

    Research output: Contribution to journal › Article

  17. Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement

    Azim, H. A., Michiels, S., Zagouri, F., Delaloge, S., Filipits, M., Namer, M., Neven, P., Symmans, W. F., Thompson, A., Andre, F., Loi, S. & Swanton, C. Mar-2013 In : Annals of Oncology. 24, 3, p. 647-654, 8 p.

    Research output: Contribution to journal › Article

  18. Improved short term surgical outcomes in Scotland for oesophageal cancer

    Young, J. A., Shimi, S. M., Waugh, L., McPhillips, G. & Thompson, A. M. Feb-2013 In : European Journal of Surgical Oncology. 39, 2, p. 131-135, 5 p.

    Research output: Contribution to journal › Article

  19. Interactions of Apoptotic Cells with Macrophages in Radiation-Induced Bystander Signaling

    Rastogi, S., Boylan, M., Wright, E. G. & Coates, P. J. Feb-2013 In : Radiation Research. 179, 2, p. 135-145, 11 p.

    Research output: Contribution to journal › Article

  20. p68/DdX5 supports β-Catenin & RNAP II during androgen receptor mediated transcription in prostate cancer

    Clark, E. L., Hadjimichael, C., Temperley, R., Barnard, A., Fuller-Pace, F. V. & Robson, C. N. 17-Jan-2013 In : PLoS ONE. 8, 1, 10 p., e54150

    Research output: Contribution to journal › Article

  21. p53 is activated in response to disruption of the pre-mRNA splicing machinery

    Allende-Vega, N., Dayal, S., Agarwala, U., Sparks, A., Bourdon, J-C. & Saville, M. K. 3-Jan-2013 In : Oncogene. 32, 1, p. 1-14, 14 p.

    Research output: Contribution to journal › Article

  22. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

    MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 1-Jan-2013 In : Scientific Reports. 3, 1275

    Research output: Contribution to journal › Article

  23. Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

    Dichtel-Danjoy, M-L., Ma, D., Dourlen, P., Chatelain, G., Napoletano, F., Robin, M., Corbet, M., Levet, C., Hafsi, H., Hainaut, P., Ryoo, H. D., Bourdon, J-C. & Mollereau, B. Jan-2013 In : Cell Death & Differentiation. 20, 1, p. 108-116, 9 p.

    Research output: Contribution to journal › Article

  24. A surveillance model for skin cancer in organ transplant recipients: A 22-year prospective study in an ethnically diverse population

    Harwood, C. A., Mesher, D., McGregor, J. M., Mitchell, L., Leedham-Green, M., Raftery, M., Cerio, R., Leigh, I. M., Sasieni, P. & Proby, C. M. Jan-2013 In : American Journal of Transplantation. 13, 1, p. 119-129, 11 p.

    Research output: Contribution to journal › Article

  25. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  26. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  27. Current controversies in breast cancer surgery

    Critchley, A. C., Thompson, A. M., Chan, H. Y. & Reed, M. W. 2013 In : Clinical Oncology. 25, 2, p. 101-108, 8 p.

    Research output: Contribution to journal › Article

  28. DEAD box RNA helicase functions in cancer

    Fuller-Pace, F. V. 2013 In : RNA Biology. 10, 1, p. 121-132, 12 p.

    Research output: Contribution to journal › Article

  29. Detecting and quantifying p53 isoforms at mRNA level in cell lines and tissues

    Khoury, M. P., Marcel, V., Fernandes, K., Diot, A., Lane, D. P. & Bourdon, J-C. 2013 p53 protocols. Deb, S. & Deb, S. P. (eds.). Totowa, N.J.: Humana Press, Vol. 962, p. 1-14 14 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

  30. Detecting p53 isoforms at protein level

    Marcel, V., Khoury, M. P., Fernandes, K., Diot, A., Lane, D. P. & Bourdon, J-C. 2013 p53 protocols. Deb, S. & Deb, S. P. (eds.). Totowa, N.J.: Humana Press, Vol. 962, p. 15-29 15 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

  31. Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines

    Silden, E., Hjelle, S. M., Wergeland, L., Sulen, A., Andresen, V., Bourdon, J-C., Micklem, D. R., McCormack, E. & Gjertsen, B. T. 2013 In : PLoS ONE. 8, 2, 11 p., e56276

    Research output: Contribution to journal › Article

  32. Longitudinal Analyses of Gut Mucosal Microbiotas in Ulcerative Colitis in Relation to Patient Age and Disease Severity and Duration

    Fite, A., Macfarlane, S., Furrie, E., Bahrami, B., Cummings, J. H., Steinke, D. T. & Macfarlane, G. T. 2013 In : Journal of Clinical Microbiology. 51, 3, p. 849-856, 8 p.

    Research output: Contribution to journal › Article

  33. Multiparameter DNA content analysis identifies distinct groups in primary breast cancer

    Dayal, J., Sales, M. J., Corver, W. E., Purdie, C. A., Jordan, L. B., Quinlan, P. R., Baker, L., ter Haar, N. T., Pratt, N. R. & Thompson, A. M. 2013 In : British Journal of Cancer. 108, 4, p. 873-880, 8 p.

    Research output: Contribution to journal › Article

  34. Photopatch testing: recommendations for a European photopatch test baseline series

    Gonçalo, M., Ferguson, J., Bonevalle, A., Bruynzeel, D. P., Giménez-Arnau, A., Goossens, A., Kerr, A., Lecha, M., Neumann, N., Niklasson, B., Pigatto, P., Rhodes, L. E., Rustemeyer, T., Sarkany, R., Thomas, P. & Wilkinson, M. 2013 In : Contact Dermatitis. 68, 4, p. 239-243, 5 p.

    Research output: Contribution to journal › Article

  35. Promoting changes in diet and physical activity in breast and colorectal cancer screening settings: an unexplored opportunity for endorsing healthy behaviors

    Anderson, A. S., Mackison, D., Boath, C. & Steele, R. 2013 In : Cancer Prevention Research. 6, 3, p. 165-172

    Research output: Contribution to journal › Article

  36. Regulation of the cardiac Na(+) pump by palmitoylation of its catalytic and regulatory subunits

    Howie, J., Tulloch, L. B., Shattock, M. J. & Fuller, W. 2013 In : Biochemical Society Transactions. 41, 1, p. 95-100, 6 p.

    Research output: Contribution to journal › Article

  37. The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example

    Pinder, S. E., Brown, J. P., Gillett, C., Purdie, C., Speirs, V., Thompson, A. M., Shaaban, A. M. & NCRI Breast Clinical Studies Grp 2013 In : Journal of Clinical Pathology. 66, 3, p. 169-177, 9 p.

    Research output: Contribution to journal › Article

  38. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  39. Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1–PP2A protein complex

    Krauss, S., Griesche, N., Jastrzebska, E., Chen, C., Rutschow, D., Achmuller, C., Dorn, S., Boesch, S. M., Lalowski, M., Wanker, E., Schneider, R. & Schweiger, S. 2013 In : Nature Communications. 4, 1511

    Research output: Contribution to journal › Article

  40. What predicts adverse outcomes in untreated primary hyperparathyroidism?: The Parathyroid Epidemiology and Audit Research Study (PEARS)

    Yu, N., Leese, G. P. & Donnan, P. T. 2013 In : Clinical Endocrinology.

    Research output: Contribution to journal › Article

  41. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8 T cells

    Finlay, D. K., Rosenzweig, E., Sinclair, L. V., Feijoo-Carnero, C., Hukelmann, J. L., Rolf, J., Panteleyev, A. A., Okkenhaug, K. & Cantrell, D. A. 17-Dec-2012 In : Journal of Experimental Medicine. 209, 13, p. 2441-2453, 13 p.

    Research output: Contribution to journal › Article

  42. Selective sampling using confocal Raman spectroscopy provides enhanced specificity for urinary bladder cancer diagnosis

    Barman, I., Dingari, N. C., Singh, G. P., Kumar, R., Lang, S. & Nabi, G. 1-Dec-2012 In : Analytical and Bioanalytical Chemistry. 404, 10, p. 3091-3099, 9 p.

    Research output: Contribution to journal › Article

  43. 2-APB-potentiated channels amplify CatSper-induced Ca signals in human sperm

    Lefièvre, L., Nash, K., Mansell, S., Costello, S., Punt, E., Correia, J., Morris, J., Kirkman-Brown, J., Wilson, S. M., Barratt, C. L. R. & Publicover, S. Dec-2012 In : Biochemical Journal. 448, 2, p. 189-200, 12 p.

    Research output: Contribution to journal › Article

  44. Tissue factor pathway inhibitor 2 (TFPI2) is commonly methylated in multiple myeloma

    Hatzimichael, E., Dasoula, A., Kounnis, V., Katsenos, A., Crook, T. & Briasoulis, E. 16-Nov-2012 In : Blood. 120, 21, 1 p., 4617

    Research output: Contribution to journal › Meeting abstract

  45. Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β

    Lu, Q., Lu, Z., Liu, Q., Guo, L., Ren, H., Fu, J., Jiang, Q., Clarke, P. R. & Zhang, C. Nov-2012 In : Cell Research. 22, p. 1562-1575, 14 p.

    Research output: Contribution to journal › Article

  46. Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer

    Smith, G., Ng, M. T. H., Shepherd, L., Herrington, C. S., Gourley, C., Ferguson, M. & Wolf, C. R. 9-Oct-2012 In : British Journal of Cancer. 107, 8, p. 1327-1336, 10 p.

    Research output: Contribution to journal › Article

  47. Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer

    Bruce, J., Thornton, A. J., Scott, N. W., Marfizo, S., Powell, R., Johnston, M., Wells, M., Heys, S. D. & Thompson, A. M. 4-Sep-2012 In : British Journal of Cancer. 107, p. 937-946, 10 p.

    Research output: Contribution to journal › Article

  48. Development of lentiviral gene therapy for type VII collagen deficient epidermolysis bullosa

    Georgiadis, C., Thrasher, A., South, A. P., McGrath, J., Qasim, W. & Di, W. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S96-S96, 1 p.

    Research output: Contribution to journal › Meeting abstract

  49. Exome level sequencing identifies candidate genes mutated in cutaneous squamous cell carcinoma progression

    South, A. P., Purdie, K. J., Watt, S. A., Harwood, C. A., Proby, C. & Leigh, I. M. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S37-S37, 1 p.

    Research output: Contribution to journal › Meeting abstract

  50. Expression of activated NOTCH1 induces terminal differentiation in squamous cell carcinoma keratinocytes

    Robinson, K. S., Purdie, K. J., Cho, R. J., Aster, J. C., Leigh, I. M. & South, A. P. Sep-2012 In : Journal of Investigative Dermatology. 132, p. S40-S40, 1 p.

    Research output: Contribution to journal › Meeting abstract

  51. Functional analysis of a genetic variant of ITGAM (CD11b/Mac-1) associated with systemic lupus erythematosus

    Sevier-Guy, C., MacPherson, M. & Fagerholm, S. Sep-2012 In : Immunology. 137, S1, p. 579-579, 1 p.

    Research output: Contribution to journal › Meeting abstract

  52. Mps1 promotes rapid centromere accumulation of Aurora B

    van der Waal, M. S., Saurin, A. T., Vromans, M. J. M., Vleugel, M., Wurzenberger, C., Gerlich, D. W., Medema, R. H., Kops, G. J. P. L. & Lens, S. M. A. Sep-2012 In : EMBO Reports. 13, 9, p. 847-854, 8 p.

    Research output: Contribution to journal › Article

  53. Phaeochromocytomas associated with PTEN mutation demonstarate tissue specificity in the anti-tumour effect of mTOR inhibition

    Taggart, C. & Fleming, S. Sep-2012 In : Journal of Pathology. 228, Suppl. 1, p. S37-S37, 1 p.

    Research output: Contribution to journal › Meeting abstract

  54. The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer

    Mohammed, Z. M. A., Going, J. J., Edwards, J., Elsberger, B., Doughty, J. C. & McMillan, D. C. 21-Aug-2012 In : British Journal of Cancer. 107, 5, p. 864-873, 10 p.

    Research output: Contribution to journal › Article

  55. Diabetes, Metformin, and Breast Cancer: Lilac Time?

    Goodwin, P. J., Thompson, A. M. & Stambolic, V. 10-Aug-2012 In : Journal of Clinical Oncology. 30, 23, p. 2812-2814, 3 p.

    Research output: Contribution to journal › Editorial

  56. Corrigendum. Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor negative breast cancer (vol 106, pg 1453, 2012)

    Ohotski, J., Long, J. S., Orange, C., Elsberger, B., Mallon, E., Doughty, J., Pyne, S., Pyne, N. J. & Edwards, J. 7-Aug-2012 In : British Journal of Cancer. 107, 4, p. 756-756, 1 p.

    Research output: Contribution to journal › Article

  57. Assessing physicians' preferences on skin cancer treatment in Europe

    Ferrandiz, L., Ruiz-de-Casas, A., Trakatelli, M., de Vries, E., Ulrich, M., Aquilina, S., Saksela, O., Majewski, S., Ranki, A., Proby, C., Magnoni, C., Pitkanen, S., Kalokasidis, K., Siskou, S., Hinrichs, B., Altsitsiadis, E., Stockfleth, E., Moreno-Ramirez, D. & EPIDERM Grp Aug-2012 In : British Journal of Dermatology. 167, p. 29-35, 7 p.

    Research output: Contribution to journal › Article

  58. Influenza A viruses control expression of proviral human p53 isoforms p53β and Delta133p53α

    Terrier, O., Marcel, V., Cartet, G., Lane, D. P., Lina, B., Rosa-Calatrava, M. & Bourdon, J-C. Aug-2012 In : Journal of Virology. 86, 16, p. 8452-8460, 9 p.

    Research output: Contribution to journal › Article

  59. Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study

    de Vries, E. , Trakatelli, M. , Kalabalikis, D. , Ferrandiz, L. , Ruiz-de-Casas, A. , Moreno-Ramirez, D. , Sotiriadis, D. , Ioannides, D. , Aquilina, S. , Apap, C. , Micallef, R. , Scerri, L. , Ulrich, M. , Pitkanen, S. , Saksela, O. , Altsitsiadis, E. , Hinrichs, B. , Magnoni, C. , Fiorentini, C. , Majewski, S. & 4 others Ranki, A., Stockfleth, E., Proby, C. & EPIDERM Grp Aug-2012 In : British Journal of Dermatology. 167, p. 1-13, 13 p.

    Research output: Contribution to journal › Article

  60. Risk factors for actinic keratosis in eight European centres: a case-control study

    Traianou, A. , Ulrich, M. , Apalla, Z. , De Vries, E. , Bakirtzi, K. , Kalabalikis, D. , Ferrandiz, L. , Ruiz-de-Casas, A. , Moreno-Ramirez, D. , Sotiriadis, D. , Ioannides, D. , Aquilina, S. , Apap, C. , Micallef, R. , Scerri, L. , Pitkanen, S. , Saksela, O. , Altsitsiadis, E. , Hinrichs, B. , Magnoni, C. & 7 others Fiorentini, C., Majewski, S., Ranki, A., Proby, C. M., Stockfleth, E., Trakatelli, M. & EPIDERM Grp Aug-2012 In : British Journal of Dermatology. 167, p. 36-42, 7 p.

    Research output: Contribution to journal › Article

  61. ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways

    Robertson, E. D., Weir, L., Romanowska, M., Leigh, I. M. & Panteleyev, A. A. 15-Jul-2012 In : Journal of Cell Science. 125, 14, p. 3320-3332, 13 p.

    Research output: Contribution to journal › Article

  62. Methylation of the calcium channel regulatory subunit alpha 2 delta-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas

    Palmieri, C., Rudraraju, B., Monteverde, M., Lattanzio, L., Gojis, O., Brizio, R., Garrone, O., Merlano, M., Syed, N., Lo Nigro, C. & Crook, T. 10-Jul-2012 In : British Journal of Cancer. 107, 2, p. 375-381, 7 p.

    Research output: Contribution to journal › Article

  63. Diminished toxicity of C-1748, 4-methyl-9-hydroxyethylamino-1-nitroacridine, compared with its demethyl analog, C-857, corresponds to its resistance to metabolism in HepG2 cells

    Wisniewska, A., Niemira, M., Jagiello, K., Potega, A., Swist, M., Henderson, C., Skwarska, A., Augustin, E., Konopa, J. & Mazerska, Z. 1-Jul-2012 In : Biochemical Pharmacology. 84, 1, p. 30-42, 13 p.

    Research output: Contribution to journal › Article

  64. Fluorescence suppression using wavelength modulated Raman spectroscopy in fiber-probe-based tissue analysis

    Praveen, B. B., Ashok, P. C., Mazilu, M., Riches, A., Herrington, S. & Dholakia, K. Jul-2012 In : Journal of Biomedical Optics. 17, 7, p. -, 6 p., 077006

    Research output: Contribution to journal › Article

  65. Impact of the revised (2008) EORTC/MSG definitions for invasive fungal disease on the rates of diagnosis of invasive aspergillosis

    Tsitsikas, D. A., Morin, A., Araf, S., Murtagh, B., Johnson, G., Vinnicombe, S., Ellis, S., Suaris, T., Wilks, M., Doffman, S. & Agrawal, S. G. Jul-2012 In : Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. 50, 5, p. 538-42, 5 p.

    Research output: Contribution to journal › Article

  66. Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling

    Sturrock, M., Terry, A. J., Xirodimas, D. P., Thompson, A. M. & Chaplain, M. A. J. Jul-2012 In : Bulletin of Mathematical Biology. 74, 7, p. 1531-1579, 49 p.

    Research output: Contribution to journal › Article

  67. The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression

    Bernard, H., Garmy-Susini, B., Ainaoui, N., Van Den Berghe, L., Peurichard, A., Javerzat, S., Bikfalvi, A., Lane, D. P., Bourdon, J. C. & Prats, A-C. 25-Jun-2012 In : Oncogene.

    Research output: Contribution to journal › Article

  68. The DSPII splice variant is crucial for desmosome-mediated adhesion in HaCaT keratinocytes

    Cabral, R. M., Tattersall, D., Patel, V., McPhail, G. D., Hatzimasoura, E., Abrams, D. J., South, A. P. & Kelsell, D. P. 15-Jun-2012 In : Journal of Cell Science. 125, 12, p. 2853-2861, 9 p.

    Research output: Contribution to journal › Article

  69. A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

    Shaaban, A. M. , Brannan, R. A. , Reall, G. , Verghese, E. T. , Hanby, A. M. , Ball, G. R. , Honarpisheh, H. , Maraqa, L. , Pollock, S. , Speirs, V. , Cserni, G. , Di Benedetto, A. , Mottolese, M. , Dent, J. , Fulford, L. , Jordan, L. , Quinlan, P. R. , Jones, J. L. , Kanthan, R. , Litwiniuk, M. & 4 others Provenzano, E., Shousha, S., Stephens, M. & Walker, R. A. 1-Jun-2012 In : Breast Cancer Research and Treatment. 133, 3, p. 949-958, 10 p.

    Research output: Contribution to journal › Article

  70. Chloride channels join the sperm 'channelome'

    Publicover, S. J. & Barratt, C. L. R. Jun-2012 In : Journal of Physiology. 590, 11, p. 2553-2554, 2 p.

    Research output: Contribution to journal › Article

  71. Invasive breast cancer: relationship between shear-wave elastographic findings and histologic prognostic factors

    Evans, A., Whelehan, P., Thomson, K., McLean, D., Brauer, K., Purdie, C., Baker, L., Jordan, L., Rauchhaus, P. & Thompson, A. Jun-2012 In : Radiology. 263, 3, p. 673-677, 5 p.

    Research output: Contribution to journal › Article

  72. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents

    Zheng, S., Laxmi, Y. R. S., David, E., Dinkova-Kostova, A. T., Shiavoni, K. H., Ren, Y., Zheng, Y., Trevino, I., Bumeister, R., Ojima, I., Wigley, W. C., Bliska, J. B., Mierke, D. F. & Honda, T. 24-May-2012 In : Journal of Medicinal Chemistry. 55, 10, p. 4837-4846, 10 p.

    Research output: Contribution to journal › Article

  73. A European multicentre photopatch test study: The European Multicentre Photopatch Test Study (EMCPPTS) taskforce

    Kerr, A. C. , Ferguson, J. , Haylett, A. K. , Rhodes, L. E. , Adamski, H. , Alomar, A. , Serra, E. , Antoniou, C. , Aubin, F. , Vigan, M. , Biedermann, T. , Fischer, J. , Bourrain, J-L. , Bruynzeel, D. , Rustemeyer, T. , Carrascosa, J. M. , Chowdhury, M. M. U. , de la Cuadra, J. , Foti, C. , Gardeazabal, J. & 22 others Gawkrodger, D. J., Gimenez-Arnau, A., Goncalo, M., Goossens, A., Ibbotson, S. H., Dawe, R. S., Lecha, M., Marguery, M-C., Neumann, N. J., Niklasson, B., Peyron, J-L., Pigatto, P., Spiewak, R., Stone, N., Tanew, A., Thomas, P., Bonnevalle, A., Wilkinson, S. M., Wolf, P., Gruber-Wackernagel, A., Wulf, H. C. & European Multictr Photopatch Test May-2012 In : British Journal of Dermatology. 166, 5, p. 1002-1009, 8 p.

    Research output: Contribution to journal › Article

  74. Axillary lymph node core biopsy for breast cancer metastases - How many needle passes are enough?

    Macaskill, E. J., Purdie, C. A., Jordan, L. B., Mclean, D., Whelehan, P., Brown, D. C. & Evans, A. May-2012 In : Clinical Radiology. 67, 5, p. 417-419, 3 p.

    Research output: Contribution to journal › Article

  75. Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues

    Matthews, S. A., San Lek, H., Morrison, V. L., Mackenzie, M. G., Zarrouk, M., Cantrell, D. & Fagerholm, S. C. May-2012 In : European Journal of Immunology. 42, 5, p. 1316-1326, 11 p.

    Research output: Contribution to journal › Article

  76. The p53 isoforms are differentially modified by Mdm2

    Camus, S., Menendez, S., Fernandes, K., Kua, N., Liu, G., Xirodimas, D. P., Lane, D. P. & Bourdon, J-C. 15-Apr-2012 In : Cell Cycle. 11, 8, p. 1646-1655, 10 p.

    Research output: Contribution to journal › Article

  77. Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer

    Ohotski, J., Long, J. S., Orange, C., Elsberger, B., Mallon, E., Doughty, J., Pyne, S., Pyne, N. J. & Edwards, J. 10-Apr-2012 In : British Journal of Cancer. 106, 8, p. 1453-1459, 7 p.

    Research output: Contribution to journal › Article

  78. Regulation of the cardiac sodium pump

    Fuller, W., Tulloch, L. B., Howie, J., Wypijewski, K. J., Shattock, M. J. & Calaghan, S. C. Apr-2012 In : Cellular and Molecular Life Sciences. 70, 8, p. 1357-1380, 24 p.

    Research output: Contribution to journal › Article

  79. Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment

    Elsberger, B., Paravasthu, D. M., Tovey, S. M. & Edwards, J. Feb-2012 In : Journal of Cancer Research and Clinical Oncology. 138, 2, p. 327-332, 6 p.

    Research output: Contribution to journal › Article

  80. Comparison of Visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer

    Mohammed, Z. M. A., McMillan, D. C., Elsberger, B., Going, J. J., Orange, C., Mallon, E., Doughty, J. C. & Edwards, J. 17-Jan-2012 In : British Journal of Cancer. 106, 2, p. 383-388, 6 p.

    Research output: Contribution to journal › Article

  81. High frequency of complex TP53 mutations in CNS metastases from breast cancer

    Lo Nigro, C., Vivenza, D., Monteverde, M., Lattanzio, L., Gojis, O., Garrone, O., Comino, A., Merlano, M., Quinlan, P. R., Syed, N., Purdie, C. A., Thompson, A., Palmieri, C. & Crook, T. 17-Jan-2012 In : British Journal of Cancer. 106, 2, p. 397-404, 8 p.

    Research output: Contribution to journal › Article

  82. MAGE-A antigens as targets in tumour therapy

    Meek, D. W. & Marcar, L. 1-Jan-2012 In : Cancer Letters.

    Research output: Contribution to journal › Article

  83. Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in cancer

    Coley, H. M., Hatzimichael, E., Blagden, S., McNeish, I., Thompson, A., Crook, T. & Syed, N. Jan-2012 In : Oncotarget. 3, 1, p. 78-83, 6 p.

    Research output: Contribution to journal › Article

  84. A comparison of the accuracy of film-screen mammography, full-field digital mammography, and digital breast tomosynthesis

    Michell, M. J., Iqbal, A., Wasan, R. K., Evans, D. R., Peacock, C., Lawinski, C. P., Douiri, A., Wilson, R. & Whelehan, P. 2012 In : Clinical Radiology. 67, 10, p. 976-981, 6 p.

    Research output: Contribution to journal › Article

  85. A rapid 3D model of abdominal organs for transcostal HIFU therapy

    Cao, R., Gao, J., Corner, G., Nabi, G. & Huang, Z. 2012

    Research output: Contribution to conference › Abstract

  86. Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics

    Abdullah, A., Kitteringham, N. R., Jenkins, R. E., Goldring, C., Higgins, L., Yamamoto, M., Hayes, J. & Park, B. K. 2012 In : Pharmacological Reports. 64, 3, p. 680-697, 18 p.

    Research output: Contribution to journal › Article

  87. Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells

    Verschooten, L., Barrette, K., Van Kelst, S., Romero, N. R., Proby, C., De Vos, R., Agostinis, P. & Garmyn, M. 2012 In : PLoS ONE. 7, 10, p. -, 11 p., e48264

    Research output: Contribution to journal › Article

  88. Beyond detection: biological physics informing progression and treatment of cancer PREFACE

    Newman, T. J. & Thompson, A. M. 2012 In : Physical Biology. 9, 6, p. -, 2 p., 060301

    Research output: Contribution to journal › Editorial

  89. Characterisation of skin autofluorescence to establish its role in distinguishing between normal and diseased skin

    Woods, J., Robinson, K., Moseley, H., Gardner, J. & Ibbotson, S. 2012 In : Lasers in Medical Science. 27, 5, p. 870

    Research output: Contribution to journal › Meeting abstract

  90. Characterizing breast phenotype with a novel measure of fibroglandular structure

    Hipwell, J. H., Griffin, L. D., Whelehan, P. J., Song, W., Zhang, X., Lesniak, J. M., Vinnicombe, S., Evans, A., Berg, J. & Hawkes, D. J. 2012 Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Maidment, A. D. A., Bakic, P. R. & Gavenonis, S. (eds.). Springer, Vol. 7361 LNCS, p. 181-188 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  91. Comparison of breast doses for digital tomosynthesis estimated from patient exposures and using PMMA breast phantoms

    Dance, D. R., Strudley, C. J., Young, K. C., Oduko, J. M., Whelehan, P. & Lindsay Mungutroy, E. H. 2012 Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Maidment, A. D. A., Bakic, P. R. & Gavenonis, S. (eds.). Springer, Vol. 7361 LNCS, p. 316-321 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  92. Crosstalk between p53 and TGF-β Signalling

    Elston, R. & Inman, G. J. 2012 In : Journal of Signal Transduction. 2012, p. 294097

    Research output: Contribution to journal › Article

  93. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

    Muller, P., Ruckova, E., Halada, P., Coates, P. J., Hrstka, R., Lane, D. P. & Vojtesek, B. 2012 In : Oncogene.

    Research output: Contribution to journal › Article

  94. DEAD-box RNA helicases as transcription cofactors

    Fuller-Pace, F. V. & Nicol, S. M. 2012 In : Methods in Enzymology. 511, p. 347-367, 21 p.

    Research output: Contribution to journal › Article

  95. Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification

    Evans, A., Whelehan, P., Thomson, K., Brauer, K., Jordan, L., Purdie, C., McLean, D., Baker, L., Vinnicombe, S. & Thompson, A. 2012 In : British Journal of Cancer. 107, 2, p. 224-9, 6 p.

    Research output: Contribution to journal › Article

  96. Dose-response relationship toxicity of CAR activators in mice

    Elcombe, C. 2012 In : Toxicology Letters. 211, p. S22-S22, 1 p.

    Research output: Contribution to journal › Meeting abstract

  97. Dual-specificity MAP kinase phosphatases (MKPs): Shaping the outcome of MAP kinase signalling

    Caunt, C. J. & Keyse, S. M. 2012 In : FEBS Journal.

    Research output: Contribution to journal › Article

  98. Embryonic stem cells: a signalling perspective

    Stavridis, M. P. 2012 Mitochondrial DNA, mitochondria, disease and stem cells. St. John, J. (ed.). Humana Press, p. 49-68 (Stem cell biology and regenerative medicine).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  99. Epigenetic Silencing of Arginino-Succinate Synthase (Ass1) Defines Arginine Depletion Therapy as A Novel Treatment Strategy for Breast Cancer

    Cavicchioli, F., Shia, A., O'Leary, K., Haley, V., Palmieri, C., Syed, N., Crook, T., Thompson, A. M., Lo Nigro, C. & Schmid, P. 2012 In : Annals of Oncology. 23, p. 532-533, 2 p., 1660P

    Research output: Contribution to journal › Meeting abstract

  100. Exposure to benzo[a]pyrene of hepatic cytochrome P450 reductase null (HRN) and P450 reductase conditional null (RCN) mice: detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-postlabelling

    Arlt, V. M., Poirier, M. C., Sykes, S. E., John, K., Moserova, M., Stiborova, M., Wolf, C. R., Henderson, C. J. & Phillips, D. H. 2012 In : Toxicology Letters. 213, 2, p. 160-166, 7 p.

    Research output: Contribution to journal › Article

  101. Fibroblast-derived dermal matrix drives development of aggressive cutaneous squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa

    Ng, Y-Z., Pourreyron, C., Salas-Alanis, J. C., Dayal, J. H. S., Cepeda-Valdes, R., Yan, W., Wright, S., Chen, M., Fine, J-D., Hogg, F. J., McGrath, J. A., Murrell, D. F., Leigh, I. M., Lane, E. B. & South, A. P. 2012 In : Cancer Research. 72, 14, p. 3522-3534, 13 p.

    Research output: Contribution to journal › Article

  102. Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

    Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218, 7 p.

    Research output: Contribution to journal › Article

  103. Giant pendulous fibroma of the breast associated with a locally advanced carcinoma of the breast

    Mullen, R., Reiss, M. M., Fleming, D., Evans, A. & Purdie, C. A. 2012 In : Breast Journal. 18, 6, p. 602-603, 2 p.

    Research output: Contribution to journal › Article

  104. Glucosinolates and isothiocyanates in health and disease

    Dinkova-Kostova, A. T. & Kostov, R. V. 2012 In : Trends in Molecular Medicine. 18, 6, p. 337-347, 11 p.

    Research output: Contribution to journal › Article

  105. Heterogeneity of p53-pathway Protein Expression in Chemosensitive Chronic Lymphocytic Leukemia: A Pilot Study

    Groves, M. J., Maccallum, S. F., Boylan, M. T., Haydock, S., Cunningham, J., Gelly, K., Gowans, D., Kerr, R., Coates, P. J. & Tauro, S. 2012 In : International Journal of Cancer. 3, p. 354-361, 8 p.

    Research output: Contribution to journal › Article

  106. Highly potent activation of Nrf2 by topical tricyclic bis(cyano enone): Implications for protection against UV radiation during thiopurine therapy

    Kalra, S., Knatko, E. V., Zhang, Y., Honda, T., Yamamoto, M. & Dinkova-Kostova, A. T. 2012 In : Cancer Prevention Research. 5, 7, p. 973-981, 9 p.

    Research output: Contribution to journal › Article

  107. Human papillomavirus infection and its association with neoplasia: from molecular biology to prevention and treatment

    Oparka, R. & Herrington, C. S. 2012 Small DNA tumour viruses. Gaston, K. (ed.). Wymondham: Caister Academic Press, p. 1-18 18 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  108. Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcome

    King, S. I., Purdie, C. A., Bray, S. E., Quinlan, P. R., Jordan, L. B., Thompson, A. M. & Meek, D. W. 2012 In : Breast Cancer Research. 14, 2, p. -, 11 p., R40

    Research output: Contribution to journal › Article

  109. Low Dose Responses of Bone Marrow to X-Rays In Vivo

    Zyuzikov, N. A., Coates, P. J., Lorimore, S. A. & Wright, E. G. 2012 Radiobiology and environmental security. Mothersill, C. E., Korogodina, V. & Seymour, C. B. (eds.). Dordrecht: Springer, p. 141-151 11 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  110. MR real-time tracking of hepatic motion during respiration in a Thiel Soft-fix cadaver

    Cox, B. F., McLeod, H., Rube, M., Vinnicombe, S., Holbrook, A. B., Eisma, R., Saliev, T., Karakitsios, I. & Melzer, A. 2012 In : Biomedizinische Technik. Biomedical Engineering. 57, Suppl. 1, p. 1049-1049, 1 p.

    Research output: Contribution to journal › Article

  111. Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics

    Miyagi, S. J., Milne, A. M., Coughtrie, M. W. H. & Collier, A. C. 2012 In : Drug Metabolism and Disposition. 40, 7, p. 1321-1327, 7 p.

    Research output: Contribution to journal › Article

  112. New standards of care in the management of the axilla

    Thompson, A. M. 2012 In : Current Opinion in Oncology. 24, 6, p. 605-611, 7 p.

    Research output: Contribution to journal › Article

  113. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene.

    Research output: Contribution to journal › Article

  114. Nrf2 orchestrates fuel partitioning for cell proliferation

    Hayes, J. D. & Ashford, M. L. J. 2012 In : Cell Metabolism. 16, 2, p. 139-141, 3 p.

    Research output: Contribution to journal › Article

  115. NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity

    Thompson, A. , Inman, G. J. & 21 others Wang, H., Lee, S., Lo Nigro, C., Lattanzio, L., Merlano, M., Monteverde, M., Matin, R., Purdie, K., Mladkova, N., Bergamaschi, D., Harwood, C., Syed, N., Szlosarek, P., Briasoulis, E., McHugh, A., Evans, A., Leigh, I., Fleming, C., Hatzimichael, E., Proby, C. & Crook, T. 2012 In : British Journal of Cancer. 106, 8, p. 1446-52, 7 p.

    Research output: Contribution to journal › Article

  116. NT5E CpG island methylation is a favourable breast cancer biomarker

    Lo Nigro, C., Monteverde, M., Lee, S., Lattanzio, L., Vivenza, D., Comino, A., Syed, N., McHugh, A., Wang, H., Proby, C., Garrone, O., Merlano, M., Hatzimichael, E., Briasoulis, E., Gojis, O., Palmieri, C., Jordan, L., Quinlan, P., Thompson, A. & Crook, T. 2012 In : British Journal of Cancer. 107, 1, p. 75-83, 9 p.

    Research output: Contribution to journal › Article

  117. Optimizing sonication protocols for transthoracic focused ultrasound surgery

    Gao, J., Volovick, A., Cao, R., Nabi, G., Cochran, S., Melzer, A. & Huang, Z. 2012 12th International Symposium on Therapeutic Ultrasound. Meairs, S. (ed.). Melville: American Institute of Physics, p. 146-151 6 p. (AIP Conference Proceedings).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  118. Optimizing sonication protocols for transthoracic focused ultrasound surgery

    Gao, J., Volovick, A., Cao, R., Nabi, G., Cochran, S., Melzer, A. & Huang, Z. 2012

    Research output: Contribution to conference › Poster

  119. Organ motion tracking in USgFUS - a feasibility study using sonoelastography

    Xiao, X., Le, N., Corner, G., Nabi, G., Melzer, A. & Huang, Z. 2012 12th International Symposium on Therapeutic Ultrasound. Meairs, S. (ed.). Melville: American Institute of Physics, p. 135-139 5 p. (AIP Conference Proceedings).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  120. Precursors of vulvovaginal squamous cell carcinoma

    Oparka, R. & Herrington, C. S. 2012 Pathology of the vulva and vagina. Brown, L. (ed.). London: Springer, p. 147-166 20 p. (Essentials of diagnostic gynecological pathology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

  121. Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis

    Delage, B., Luong, P., Maharaj, L., O'Riain, C., Syed, N., Crook, T., Hatzimichael, E., Papoudou-Bai, A., Mitchell, T. J., Whittaker, S. J., Cerio, R., Gribben, J., Lemoine, N., Bomalaski, J., Li, C-F., Joel, S., Fitzgibbon, J., Chen, L-T. & Szlosarek, P. W. 2012 In : Cell Death and Disease. 3, 7, e342

    Research output: Contribution to journal › Article

  122. Radiation-induced bone marrow apoptosis, inflammatory bystander-type signaling and tissue cytotoxicity

    Mukherjee, D., Coates, P. J., Rastogi, S., Lorimore, S. A. & Wright, E. G. 2012 In : International Journal of Radiation Biology.

    Research output: Contribution to journal › Article

  123. Rapid 3D human ribcage and kidney modeling for transcostal HIFU surgery

    Cao, R., Gao, J., Melzer, A., Nabi, G. & Huang, Z. 2012 12th International Symposium on Therapeutic Ultrasound. Meairs, S. (ed.). Melville: American Institute of Physics, p. 95-100 6 p. (AIP Conference Proceedings).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  124. Real-time organ motion tracking in high intensity ultrasound treatment using sonoelastography: a feasibility study

    Xiao, X., Huang, Z., Melzer, A., Corner, G. & Nabi, G. 2012

    Research output: Contribution to conference › Abstract

  125. Site-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBP) CpG island in breast cancer is associated with metastatic relapse

    Palmieri, C., Monteverde, M., Lattanzio, L., Gojis, O., Rudraraju, B., Fortunato, M., Syed, N., Thompson, A., Garrone, O., Merlano, M., Lo Nigro, C. & Crook, T. 2012 In : British Journal of Cancer. 107, 4, p. 732-738, 7 p.

    Research output: Contribution to journal › Article

  126. Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study

    Mackenzie, I. S., Macdonald, T. M., Thompson, A., Morant, S. & Wei, L. 2012 In : British Medical Journal. 345, p. e4447, 12 p., e4447

    Research output: Contribution to journal › Article

  127. Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP Axis

    Rada, P., Rojo, A. I., Evrard-Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García-Mayoral, M. F., Van Leuven, F., Hayes, J. D., Bertho, G. & Cuadrado, A. 2012 In : Molecular and Cellular Biology. 32, 17, p. 3486-99, 14 p.

    Research output: Contribution to journal › Article

  128. Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins

    Boldrup, L., Coates, P. J., Wahlgren, M., Laurell, G. & Nylander, K. 2012 In : Journal of Carcinogenesis. 11, 1, p. 18

    Research output: Contribution to journal › Article

  129. Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease

    Castro-Caldas, M., Carvalho, A. N., Rodrigues, E., Henderson, C. J., Wolf, C. R., Rodrigues, C. M. P. & Gama, M. J. 2012 In : Molecular Neurobiology. 46, 2, p. 475-486, 12 p.

    Research output: Contribution to journal › Article

  130. The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma

    Thompson, A. & 21 others Hatzimichael, E., Lo Nigro, C., Lattanzio, L., Syed, N., Shah, R., Dasoula, A., Janczar, K., Vivenza, D., Monteverde, M., Merlano, M., Papoudou-Bai, A., Bai, M., Schmid, P., Stebbing, J., Bower, M., Dyer, M. J. S., Karran, L. E., Elguetakarstegl, C., Farrell, P. J., Briasoulis, E. & Crook, T. 2012 In : British Journal of Cancer. 107, 8, p. 1423-1432, 10 p.

    Research output: Contribution to journal › Article

  131. The effect of ABCG2 transporter inhibition and ferrochelatase activity on PDT efficacy: an in-vivo study

    Barron, G., Woods, J. & Moseley, H. 2012 In : Lasers in Medical Science. 27, 5, p. 857

    Research output: Contribution to journal › Meeting abstract

  132. The in vivo expression of radiation-induced chromosomal instability has an inflammatory mechanism

    Mukherjee, D., Coates, P. J., Lorimore, S. A. & Wright, E. G. 2012 In : Radiation Research. 177, 1, p. 18-24, 7 p.

    Research output: Contribution to journal › Article

  133. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

    Nicol, S. M., Bray, S. E., Derek Black, H., Lorimore, S. A., Wright, E. G., Lane, D. P., Meek, D. W., Coates, P. J. & Fuller-Pace, F. V. 2012 In : Oncogene.

    Research output: Contribution to journal › Article

  134. Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism

    Westendorf, A. F., Woods, J. A., Korpis, K., Farrer, N. J., Salassa, L., Robinson, K., Appleyard, V., Murray, K., Grünert, R., Thompson, A. M., Sadler, P. J. & Bednarski, P. J. 2012 In : Molecular Cancer Therapeutics. 11, 9, p. 1894-1904, 11 p.

    Research output: Contribution to journal › Article

  135. Transcriptional profiling of formalin fixed paraffin embedded tissue: pitfalls and recommendations for identifying biologically relevant changes

    Rentoft, M., Coates, P. J., Laurell, G. & Nylander, K. 2012 In : PLoS ONE. 7, 4, p. -, 8 p., e35276

    Research output: Contribution to journal › Article

  136. Transforming Growth Factor-β directly induces PUMA during the rapid induction of apoptosis in Myc-driven B-cell lymphomas.

    Spender, L. C., Carter, M. J., O'Brien, D. I., Clark, L. J., Yu, J., Michalak, E. M., Happo, L., Cragg, M. S. & Inman, G. J. 2012 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  137. Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling

    Bose, A., Teh, M-T., Hutchison, I. L., Wan, H., Leigh, I. M. & Waseem, A. 2012 In : PLoS ONE. 7, 6, e38599

    Research output: Contribution to journal › Article

  138. Biological functions of p53 isoforms through evolution: Lessons from animal and cellular models

    Marcel, V., Dichtel-Danjoy, M-L., Sagne, C., Hafsi, H., Ma, D., Ortiz-Cuaran, S., Olivier, M., Hall, J., Mollereau, B., Hainaut, P. & Bourdon, J-C. Dec-2011 In : Cell Death & Differentiation. 18, 12, p. 1815-1824, 10 p.

    Research output: Contribution to journal › Scientific review

  139. mTORC2 targets AGC kinases through Sin1-dependent recruitment

    Cameron, A. J. M., Linch, M. D., Saurin, A. T., Escribano, C. & Parker, P. J. 15-Oct-2011 In : Biochemical Journal. 439, p. 287-297, 11 p.

    Research output: Contribution to journal › Article

  140. Epigenetic Dysregulation of Novel Genes in Melanoma

    Wang, H., McHugh, A., Matin, R., Fleming, C., Leigh, I., Harwood, C., Crook, T., Inman, G. & Proby, C. Sep-2011 In : Journal of Investigative Dermatology. 131, p. S114-S114, 1 p.

    Research output: Contribution to journal › Book/Film/Article review

  141. A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

    Girardini, J. E., Napoli, M., Piazza, S., Rustighi, A., Marotta, C., Radaelli, E., Capaci, V., Jordan, L., Quinlan, P., Thompson, A., Mano, M., Rosato, A., Crook, T., Scanziani, E., Means, A. R., Lozano, G., Schneider, C. & Del Sal, G. 12-Jul-2011 In : Cancer Cell. 20, 1, p. 79-91, 13 p.

    Research output: Contribution to journal › Article

  142. Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway

    Terrier, O., Josset, L., Textoris, J., Marcel, V., Cartet, G., Ferraris, O., N'Guyen, C., Lina, B., Diaz, J-J., Bourdon, J-C. & Rosa-Calatrava, M. 8-Jun-2011 In : Virology Journal. 8, 11 p., 285

    Research output: Contribution to journal › Article

  143. The role of P63 in cancer, stem cells and cancer stem cells

    Nekulova, M., Holcakova, J., Coates, P. & Vojtesek, B. Jun-2011 In : Cellular & Molecular Biology Letters. 16, 2, p. 296-327, 32 p.

    Research output: Contribution to journal › Scientific review

  144. Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors

    Dalvai, M., Mondesert, O., Bourdon, J-C., Ducommun, B. & Dozier, C. 12-May-2011 In : Oncogene. 30, 19, p. 2282-2288, 7 p.

    Research output: Contribution to journal › Article

  145. Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

    Saurin, A. T., van der Waal, M. S., Medema, R. H., Lens, S. M. A. & Kops, G. J. P. L. May-2011 In : Nature Communications. 2, 9 p., ARTN 316

    Research output: Contribution to journal › Article

  146. Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model

    Levova, K., Moserova, M., Kotrbova, V., Sulc, M., Henderson, C. J., Wolf, C. R., Phillips, D. H., Frei, E., Schmeiser, H. H., Mares, J., Arlt, V. M. & Stiborova, M. May-2011 In : Toxicological Sciences. 121, 1, p. 43-56, 14 p.

    Research output: Contribution to journal › Article

  147. Epigenetic dysregulation of novel candidate genes in malignant melanoma

    Wang, H., McHugh, A. T., Matin, R., Fleming, C., Leigh, I. M., Harwood, C., Crook, T., Inman, G. & Proby, C. 11-Apr-2011 In : British Journal of Dermatology. 164, 4, p. 916-916, 1 p.

    Research output: Contribution to journal › Book/Film/Article review

  148. Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome

    Henry, L. A., Johnson, D. A., Sarrio, D., Lee, S., Quinlan, P. R., Crook, T., Thompson, A. M., Reis-Filho, J. S. & Isacke, C. M. Mar-2011 In : Oncogene. 30, 9, p. 1046-1058, 13 p.

    Research output: Contribution to journal › Article

  149. Involvement of p53 in ribosomal RNA processing and translational control

    Ghayad, S. E., Belin, S., Morel, A-P., Hacot, S., Mertani, H. C., Vendrell, J., Bourdon, J-C., Prats, A-C., Puisieux, A. & Diaz, J-J. Mar-2011 In : Bulletin du Cancer. 98, S1, p. S30-S30, 1 p.

    Research output: Contribution to journal › Meeting abstract

  150. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

    Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D. & Cuadrado, A. Mar-2011 In : Molecular and Cellular Biology. 31, 6, p. 1121-1133, 13 p.

    Research output: Contribution to journal › Article

  151. Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

    Bell, K. F., Al-Mubarak, B., Fowler, J. H., Baxter, P. S., Gupta, K., Tsujita, T., Chowdhry, S., Patani, R., Chandran, S., Horsburgh, K., Hayes, J. D. & Hardingham, G. E. 4-Jan-2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 1, p. E1-E2, 2 p.

    Research output: Contribution to journal › Letter

  152. miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples

    Rentoft, M., Fahlén, J., Coates, P. J., Laurell, G., Sjöström, B., Rydén, P. & Nylander, K. Jan-2011 In : International Journal of Oncology. 38, 1, p. 61-9, 9 p.

    Research output: Contribution to journal › Article

  153. A web-based data analytical tool for translational researchers

    Quinlan, P. R., Jordan, L. B., Purdie, C. A., Thompson, A. & Reed, C. 2011

    Research output: Contribution to conference › Abstract

  154. Correlations between shear wave elastography and mammographic findings in invasive breast cancer

    Budak, M. J., Thomson, K., Whelehan, P., Vinnicombe, S. & Evans, A. 2011 In : Breast Cancer Research. 13, S1, p. -, 1 p., O3

    Research output: Contribution to journal › Meeting abstract

  155. Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity

    Boldrup, L., Coates, P. J., Laurell, G. & Nylander, K. 2011 In : Oral Oncology. 47, 9, p. 861-865, 5 p.

    Research output: Contribution to journal › Article

  156. Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis

    Gu, X., Nylander, E., Coates, P. J. & Nylander, K. 2011 In : Acta Dermato-Venereologica. 91, 4, p. 392-397, 6 p.

    Research output: Contribution to journal › Article

  157. Improving the validity of breast density assessment

    Eadie, A., Whelehan, P., Baker, L., Berg, J. & Evans, A. 2011 In : Breast Cancer Research. 13, S1, p. -, 1 p.

    Research output: Contribution to journal › Meeting abstract

  158. Induction and activation of the p53 pathway: a role for the protein kinase CK2?

    Meek, D. W. & Cox, M. 2011 In : Molecular and Cellular Biochemistry. 356, 1-2, p. 133-138, 6 p.

    Research output: Contribution to journal › Article

  159. Lack of nontargeted effects in murine bone marrow after low-dose in vivo X irradiation

    Zyuzikov, N. A., Coates, P. J., Parry, J. M., Lorimore, S. A. & Wright, E. G. 2011 In : Radiation Research. 175, 3, p. 322-7, 6 p.

    Research output: Contribution to journal › Article

  160. Reporting and management of breast lesions detected using MRI

    Dall, B. J. G., Vinnicombe, S. & Gilbert, F. J. 2011 In : Clinical Radiology. 66, 12, p. 1120-8, 9 p.

    Research output: Contribution to journal › Article

  161. Peroxiredoxin 6 is recruited to the cardiac sodium pump complex by phospholemman

    Howie, J., Tulloch, L. B., Beddie, E. J., Shattock, M. J. & Fuller, W. 23-Nov-2010 In : Circulation. 122, 21, p. -, 1 p., A21311

    Research output: Contribution to journal › Meeting abstract

  162. Phospholemman palmitoylation: a novel means of sodium pump regulation

    Tulloch, L. B., Shattock, M. J. & Fuller, W. 23-Nov-2010 In : Circulation. 122, 21, p. -, 1 p., A21298

    Research output: Contribution to journal › Meeting abstract

  163. Little Effect on p63 but Significant Effect on miR-21 and miR-125b by NB-UVB Phototherapy on Psoriatic Lesions

    Gu, X., Nylander, E., Coates, P. & Nylander, K. Sep-2010 In : Journal of Investigative Dermatology. 130, S2, p. S49-S49, 1 p.

    Research output: Contribution to journal › Meeting abstract

  164. Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter

    Inman, G. J. & 27 others Hannigan, A., Smith, P., Kalna, G., Lo Nigro, C., Orange, C., O'Brien, D. I., Shah, R., Syed, N., Spender, L. C., Herrera, B., Thurlow, J. K., Lattanzio, L., Monteverde, M., Maurer, M. E., Buffa, F. M., Mann, J., Chu, D. C. K., West, C. M. L., Patridge, M., Oien, K. A., Cooper, J. A., Frame, M. C., Harris, A. L., Hiller, L., Nicholson, L. J., Gasco, M. & Crook, T. Aug-2010 In : Journal of Clinical Investigation. 120, 8, p. 2842-2857, 16 p.

    Research output: Contribution to journal › Article

  165. Finding the middle ground: how kinetochores power chromosome congression

    Kops, G. J. P. L., Saurin, A. T. & Meraldi, P. Jul-2010 In : Cellular and Molecular Life Sciences. 67, 13, p. 2145-2161, 17 p.

    Research output: Contribution to journal › Scientific review

  166. False-negative monochromator phototesting in chronic actinic dermatitis

    Kerr, A. C., Dawe, R. S., Lowe, G. & Ferguson, J. Jun-2010 In : British Journal of Dermatology. 162, 6, p. 1406-1408, 4 p.

    Research output: Contribution to journal › Letter

  167. Can radiographers be trained to deliver an intervention to raise breast cancer awareness, and thereby promote early presentation of breast cancer, in older women?

    Omar, L., Burgess, C. C., Tucker, L. D., Whelehan, P. & Ramirez, A. J. May-2010 In : Radiography. 16, 2, p. 101-107, 7 p.

    Research output: Contribution to journal › Article

  168. SURGICAL ONCOLOGY: Why biopsying metastatic breast cancer should be routine

    Sharma, A., Crook, T., Thompson, A. & Palmieri, C. Feb-2010 In : Nature Reviews Clinical Oncology. 7, 2, p. 71-74, 4 p.

    Research output: Contribution to journal › Editorial

  169. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

    Hayes, J. D., McMahon, M., Chowdhry, S. & Dinkova-Kostova, A. T. 2010 In : Antioxidants & Redox Signaling. 13, 11, p. 1713-1748, 36 p.

    Research output: Contribution to journal › Article

  170. Changes and tracking of mammographic density in relation to Pike's model of breast tissue aging: a UK longitudinal study

    McCormack, V. A., Perry, N. M., Vinnicombe, S. J. & Dos Santos Silva, I. 2010 In : International Journal of Cancer. 127, 2, p. 452-461, 10 p.

    Research output: Contribution to journal › Article

  171. Do common solid tumours express C-reactive protein?

    Shepherd, S., Edwards, J., McMillan, D. & Elsberger, B. 2010 In : British Journal of Surgery. 97, S2, p. 77-77, 1 p.

    Research output: Contribution to journal › Meeting abstract

  172. Expression of hypoxia inducible factor-1 alpha in matched hormone naive and castrate resistant prostate cancer specimens

    Elsberger, B., Lankston, L., Orange, C., Underwood, M. A. & Edwards, J. 2010 In : Cancer Biomarkers. 8, 1, p. 1-9, 9 p.

    Research output: Contribution to journal › Article

  173. Inflammatory breast cancer: the disease, the biology, the treatment

    Robertson, F. M., Bondy, M., Yang, W., Yamauchi, H., Wiggins, S., Kamrudin, S., Krishnamurthy, S., Le-Petross, H., Bidaut, L., Player, A. N., Barsky, S. H., Woodward, W. A., Buchholz, T., Lucci, A., Ueno, N. & Cristofanilli, M. 2010 In : CA: a Cancer Journal for Clinicians. 60, 6, p. 351-375, 25 p.

    Research output: Contribution to journal › Article

  174. Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis

    Chowdhry, S., Nazmy, M. H., Meakin, P. J., Dinkova-Kostova, A. T., Walsh, S. V., Tsujita, T., Dillon, J. F., Ashford, M. L. J. & Hayes, J. D. 2010 In : Free Radical Biology and Medicine. 48, 2, p. 357-371, 15 p.

    Research output: Contribution to journal › Article

  175. Radiation-induced delayed bystander-type effects mediated by hemopoietic cells

    Burr, K. L., Robinson, J. I., Rastogi, S., Boylan, M. T., Coates, P. J., Lorimore, S. A. & Wright, E. G. 2010 In : Radiation Research. 173, 6, p. 760-8, 9 p.

    Research output: Contribution to journal › Article

  176. RCPE UK Consensus Statement on Diabetes

    Anderson, A., Boyd, K., Christie, B., Claridge, C., Currie, P., Doherty, T., Dorward, D., Elder, A., Hadley-Brown, M., Hughes, D., Jackson, M., Jung, R., Marshall, S., MacKinnon, M., Pollock, A. & Ritchie, L. 2010 In : Journal of the Royal College of Physicians of Edinburgh. 40, 2, p. 130-131

    Research output: Contribution to journal › Comment/debate

  177. Teenage pregnancies

    Anderson, A. S. & Wrieden, W. L. 2010 Maternal-fetal nutrition during pregnancy and lactation. Symonds, M. E. & Ramsay, M. M. (eds.). Cambridge: Cambridge University Press, p. 119-128 10 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  178. Transforming growth factor-beta co-receptor endoglin suppresses breast cancer invasion and metastasis

    Henry, L. A., Johnson, D. J., Lee, S., Quinlan, P. R., Crook, T., Thompson, A. M., Reis-Filho, J. S. & Isacke, C. M. 2010 In : Breast Cancer Research. 12, Suppl. 1, p. S2-S2, 1 p., O6

    Research output: Contribution to journal › Book/Film/Article review

  179. Gene expression profiling of archival tongue squamous cell carcinomas provides sub-classification based on DNA repair genes

    Rentoft, M., Laurell, G., Coates, P. J., Sjöström, B. & Nylander, K. Dec-2009 In : International Journal of Oncology. 35, 6, p. 1321-30, 10 p.

    Research output: Contribution to journal › Article

  180. Promoting early presentation of breast cancer by older women: A preliminary evaluation of a one-to-one health professional-delivered intervention

    Burgess, C. C., Linsell, L., Kapari, M., Omar, L., Michell, M., Whelehan, P., Richards, M. A. & Ramirez, A. J. Nov-2009 In : Journal of Psychosomatic Research. 67, 5, p. 377-387, 12 p.

    Research output: Contribution to journal › Article

  181. Recognition of an intra-chain tandem 14-3-3 binding site within PKC epsilon

    Kostelecky, B., Saurin, A. T., Purkiss, A., Parker, P. J. & McDonald, N. Q. Sep-2009 In : EMBO Reports. 10, 9, p. 983-989, 7 p.

    Research output: Contribution to journal › Article

  182. PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity

    Cameron, A. J. M., Escribano, C., Saurin, A. T., Kostelecky, B. & Parker, P. J. Jun-2009 In : Nature Structural & Molecular Biology. 16, 6, p. 624-630, 8 p.

    Research output: Contribution to journal › Article

  183. The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer

    Shah, R., Smith, P., Purdie, C., Quinlan, P., Baker, L., Aman, P., Thompson, A. M. & Crook, T. 12-May-2009 In : British Journal of Cancer. 100, 10, p. 1687-1696, 10 p.

    Research output: Contribution to journal › Article

  184. Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment

    Hrstka, R., Coates, P. J. & Vojtesek, B. Mar-2009 In : Journal of Cellular and Molecular Medicine. 13, 3, p. 440-53, 14 p.

    Research output: Contribution to journal › Scientific review

  185. Protein kinase C epsilon in cell division Control of abscission

    Saurin, A. T., Brownlow, N. & Parker, P. J. 15-Feb-2009 In : Cell Cycle. 8, 4, p. 549-555, 7 p.

    Research output: Contribution to journal › Article

  186. DeltaNp63 isoforms differentially regulate gene expression in squamous cell carcinoma: identification of Cox-2 as a novel p63 target

    Boldrup, L., Coates, P. J., Gu, X. & Nylander, K. 2009 In : Journal of Pathology. 218, 4, p. 428-436, 9 p.

    Research output: Contribution to journal › Article

  187. Estrogen regulation of p53 isoforms in the human breast cancer cell line MCF7

    Vendrell, J. A., Bourdon, J., Cohen, P. A. & Thompson, A. M. 2009 In : Cancer Research. 69, 2 Suppl. 1, 4067

    Research output: Contribution to journal › Meeting abstract

  188. Phase contrast imaging of breast tumours with synchrotron radiation

    Olivo, A., Rigon, L., Vinnicombe, S. J., Cheung, K. C., Ibison, M. & Speller, R. D. 2009 In : Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for use in Agriculture, Industry and Medicine. 67, 6, p. 1033-41, 9 p.

    Research output: Contribution to journal › Article

  189. Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women

    McCormack, V. A., Dowsett, M., Folkerd, E., Johnson, N., Palles, C., Coupland, B., Holly, J. M., Vinnicombe, S. J., Perry, N. M. & dos Santos Silva, I. 2009 In : Breast Cancer Research. 11, 3, p. R38, 10 p.

    Research output: Contribution to journal › Article

  190. The identification and characterisation of compounds with insulin-like properties

    Cameron, A. R., Harthill, J. & Rena, G. 2009 In : Diabetologia. 52, Suppl. 1, p. S203-S203, 1 p., PS 29

    Research output: Contribution to journal › Meeting abstract

  191. The regulated assembly of a PKC epsilon complex controls the completion of cytokinesis

    Saurin, A. T., Durgan, J., Cameron, A. J., Faisal, A., Marber, M. S. & Parker, P. J. Aug-2008 In : Nature Cell Biology. 10, 8, p. 891-901, 11 p.

    Research output: Contribution to journal › Article

  192. The scaffold MyD88 acts to couple protein kinase C epsilon to toll-like receptors

    Faisal, A., Saurin, A., Gregory, B., Foxwell, B. & Parker, P. J. 4-Jul-2008 In : Journal of Biological Chemistry. 283, 27, p. 18591-18600, 10 p.

    Research output: Contribution to journal › Article

  193. The identification and characterization of novel PKC epsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily

    Durgan, J., Cameron, A. J., Saurin, A. I., Hanrahan, S., Totty, N., Messing, R. O. & Parker, P. J. 15-Apr-2008 In : Biochemical Journal. 411, p. 319-331, 13 p.

    Research output: Contribution to journal › Article

  194. Promoting early presentation of breast cancer: development of a psycho-educational intervention

    Burgess, C. C., Bish, A. M., Hunter, H. S., Salkovskis, P., Michell, M., Whelehan, P. & Ramirez, A. J. Mar-2008 In : Chronic Illness. 4, 1, p. 13-27, 15 p.

    Research output: Contribution to journal › Article

  195. Accessing Healthy Food: availability and price of a healthy food basket in Scotland

    Dawson, J., Marshall, D., Taylor, M., Cummins, S., Sparks, L. & Anderson, A. S. 2008 In : Journal of Marketing Management. 24, 9/10, p. 893-913, 21 p.

    Research output: Contribution to journal › Article

  196. Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a

    Cameron, A. R., Anton, S., Melville, L., Houston, N. P., Dayal, S., McDougall, G. J., Stewart, D. & Rena, G. 2008 In : Aging Cell. 7, 1, p. 69-77, 9 p.

    Research output: Contribution to journal › Article

  197. Chromosomal instability in unirradiated hemaopoietic cells induced by macrophages exposed in vivo to ionizing radiation

    Lorimore, S. A., Chrystal, J. A., Robinson, J. I., Coates, P. J. & Wright, E. G. 2008 In : Cancer Research. 68, 19, p. 8122-6, 5 p.

    Research output: Contribution to journal › Article

  198. Does MK5 reconcile classical and atypical MAP kinases?

    Perander, M., Keyse, S. M. & Seternes, O-M. 2008 In : Frontiers in Bioscience. 13, 12, p. 4617-4624, 8 p.

    Research output: Contribution to journal › Article

  199. Identification of small compounds that mimic insulin action on the transcription factor FOXO1a

    Cameron, A., Anton, S., Reetoo, N., Melville, L., Houston, N., Dayal, S., McDougall, G., Stewart, D. & Rena, G. 2008 In : Diabetes. 57, Suppl., p. A699-A700, 2 p.

    Research output: Contribution to journal › Meeting abstract

  200. Indirect macrophage responses to ionizing radiation: implications for genotype-dependent bystander signaling

    Coates, P. J., Rundle, J. K., Lorimore, S. A. & Wright, E. G. 2008 In : Cancer Research. 68, 2, p. 450-6, 7 p.

    Research output: Contribution to journal › Article

  201. Microbial Colonization of the esophagus in patients with gastroesophageal reflux disease and Barrett's esophagus

    Blackett, K. L., Macfarlane, G. T., Dillon, J. F. & Macfarlane, S. 2008 Abstracts of the General Meeting of the American Society for Microbiology. American Society for Microbiology, Vol. 108, p. 236-236 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  202. Obesity and Cancer Risk: a weighty problem in the 21st century

    Anderson, A. S. & Caswell, S. 2008 In : The Biologist. 55, 2, p. 100-104

    Research output: Contribution to journal › Article

  203. Ongoing activation of p53 pathway responses is a long-term consequence of radiation exposure in vivo and associates with altered macrophage activities

    Coates, P. J., Robinson, J. I., Lorimore, S. A. & Wright, E. G. 2008 In : Journal of Pathology. 214, 5, p. 610-6, 7 p.

    Research output: Contribution to journal › Article

  204. p63 contributes to cell invasion and migration in squamous cell carcinoma of the head and neck

    Gu, X., Coates, P. J., Boldrup, L. & Nylander, K. 2008 In : Cancer Letters. 263, 1, p. 26-34, 9 p.

    Research output: Contribution to journal › Article

  205. The identification and characterisation of compounds with insulin-like properties

    Cameron, A. R., Harthill, J. & Rena, G. 2008

    Research output: Contribution to conference › Poster

  206. Early detection of cervical neoplasia by Raman spectroscopy

    Jess, P. R. T., Smith, D. D. W., Mazilu, M., Dholakia, K., Riches, A. C. & Herrington, C. S. 15-Dec-2007 In : International Journal of Cancer. 121, 12, p. 2723-2728, 6 p.

    Research output: Contribution to journal › Meeting abstract

  207. Melanocortin 1 receptor (MC1R) genotype influences erythemal sensitivity to psoralen-ultraviolet A photochemotherapy

    Smith, G., Wilkie, M. J. V., Deeni, Y. Y., Farr, P. M., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Dec-2007 In : British Journal of Dermatology. 157, 6, p. 1230-4, 5 p.

    Research output: Contribution to journal › Article

  208. p53 and Mdm2: not all cells are equal

    Coates, P. J. Dec-2007 In : Journal of Pathology. 213, 4, p. 357-9, 3 p.

    Research output: Contribution to journal › Editorial

  209. The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane

    Draeby, I., Woods, Y. L., la Cour, J. M., Mollerup, J., Bourdon, J-C. & Berchtold, M. W. 1-Nov-2007 In : Archives of Biochemistry and Biophysics. 467, 1, p. 87-94, 8 p.

    Research output: Contribution to journal › Article

  210. The disruption of hepatic cytochrome P450 reductase afters mouse lipid metabolism

    Mutch, D. M., Klocke, B., Morrison, P., Murray, C. A., Henderson, C. J., Seifert, M. & Williamson, G. Oct-2007 In : Journal of Proteome Research. 6, 10, p. 3976-3984, 9 p.

    Research output: Contribution to journal › Article

  211. Differential expression of cyclin-dependent kinase inhibitors and apoptosis-related proteins in endocervical lesions

    El-Ghobashy, A. A., Shaaban, A. M., Innes, J., Prime, W. & Herrington, C. S. Sep-2007 In : European Journal of Cancer. 43, 13, p. 2011-2018, 8 p.

    Research output: Contribution to journal › Article

  212. Simultaneous Raman micro-spectroscopy of optically trapped and stacked cells

    Jess, P. R. T., Garces-Chavez, V., Riches, A. C., Herrington, C. S. & Dholakia, K. Sep-2007 In : Journal of Raman Spectroscopy. 38, 9, p. 1082-1088, 7 p.

    Research output: Contribution to journal › Article

  213. Development of a liquid Chromatography-Electrospray ionization tandem mass spectrometry method for detecting Oxaliplatin-DNA intrastrand cross-links in biological samples

    Le Pla, R. C., Ritchie, K. J., Henderson, C. J., Wolf, C. R., Harrington, C. F. & Farmer, P. B. Aug-2007 In : Chemical Research in Toxicology. 20, 8, p. 1177-1182, 6 p.

    Research output: Contribution to journal › Article

  214. Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells

    Johnson, C. E., Crawford, B. E., Stavridis, M., Ten Dam, G., Wat, A. L., Rushton, G., Ward, C. M., Wilson, V., van Kuppevelt, T. H., Esko, J. D., Smith, A., Gallagher, J. T. & Merry, C. L. R. Aug-2007 In : Stem Cells. 25, 8, p. 1913-23, 11 p.

    Research output: Contribution to journal › Article

  215. p53 and its isoforms in cancer

    Bourdon, J-C. 31-Jul-2007 In : British Journal of Cancer. 97, 3, p. 277-282, 6 p.

    Research output: Contribution to journal › Scientific review

  216. Fluorescence suppression within Raman spectroscopy using annular beam excitation

    Cormack, I. G., Mazilu, M., Dholakia, K. & Herrington, C. S. 9-Jul-2007 In : Applied Physics Letters. 91, 2, p. -, 3 p., 023903

    Research output: Contribution to journal › Article

  217. Conditional deletion of cytochrome P450 oxidoreductase in the liver and gastrointestinal tract: A new model for studying the functions of the P450 system

    Finn, R. D., McLaren, A. W., Carrie, D., Henderson, C. J. & Wolf, C. R. Jul-2007 In : Journal of Pharmacology and Experimental Therapeutics. 322, 1, p. 40-47, 8 p.

    Research output: Contribution to journal › Article

  218. Selective induction of apoptosis by leptomycin B in keratinocytes expressing HPV oncogenes

    Gray, L. J., Bjelogrlic, P., Appleyard, V. C. L., Thompson, A. M., Jolly, C. E., Lain, S. & Herrington, C. S. 1-Jun-2007 In : International Journal of Cancer. 120, 11, p. 2317-2324, 8 p.

    Research output: Contribution to journal › Article

  219. Conformation-specific antibodies targeting the trimer-of-hairpins motif of the human T-cell leukemia virus type 1 transmembrane glycoprotein recognize the viral envelope but fail to neutralize viral entry

    Mirsaliotis, A., Nurkiyanova, K., Lamb, D., Woof, J. M. & Brighty, D. W. Jun-2007 In : Journal of Virology. 81, 11, p. 6019-6031, 13 p.

    Research output: Contribution to journal › Article

  220. Fluorescence spectroscopy of an in vitro model of human cervical precancer identifies neoplastic phenotype

    Martin, S. F., Wood, A. D., McRobbie, M. M., Mazilu, M., McDonald, M. P., Samuel, I. D. W. & Herrington, C. S. 1-May-2007 In : International Journal of Cancer. 120, 9, p. 1964-1970, 7 p.

    Research output: Contribution to journal › Article

  221. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression

    Wilkie, M. J. V., Smith, D., Reid, I. C., Day, R. K., Matthews, K., Wolf, R., Blackwood, D. & Smith, G. Mar-2007 In : Pharmacogenetics and Genomics. 17, 3, p. 207-215, 9 p.

    Research output: Contribution to journal › Article

  222. Exposure to benzo[A]pyrene in the hepatic cytochrome p450 oxidoreductase null mouse: detoxification by hepatic cytochrome p450 is more important than metabolic activation

    Arlt, V. M., Stiborova, M., Henderson, C. J., Thiemann, M., Frei, E., Singh, R., da Costa, G. G., Schmitz, O. J., Farmer, P. B., Wolf, C. R. & Phillips, D. H. Mar-2007 In : Naunyn-Schmiedeberg's Archives of Pharmacology. 375, Supplement 1, p. 73-73, 1 p., 352

    Research output: Contribution to journal › Meeting abstract

  223. A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification

    Stavridis, M. P., Lunn, J. S., Collins, B. J. & Storey, K. G. 2007 In : Development. 134, 16, p. 2889-94, 6 p.

    Research output: Contribution to journal › Article

  224. A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin

    Elderkin, S., Maertens, G. N., Endoh, M., Mallery, D. L., Morrice, N., Koseki, H., Peters, G., Brockdorff, N. & Hiom, K. 2007 In : Molecular Cell. 28, 1, p. 107-20, 14 p.

    Research output: Contribution to journal › Article

  225. Cerebral metastasis of peripheral primitive neuroectodermal tumour (pPNET): use of cytogenetic abnormalities in diagnosis

    Ross, J., Whittle, I. R., Fleming, S. & Kurian, K. M. 2007 In : Neuropathology and Applied Neurobiology. 33, 4, p. 471-4, 4 p.

    Research output: Contribution to journal › Article

  226. DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck

    Boldrup, L., Coates, P. J., Gu, X. & Nylander, K. 2007 In : Journal of Pathology. 213, 4, p. 384-391, 8 p.

    Research output: Contribution to journal › Article

  227. Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases

    Owens, D. M. & Keyse, S. M. 2007 In : Oncogene. 26, 22, p. 3203-13, 11 p.

    Research output: Contribution to journal › Article

  228. Expression of p53 isoforms in squamous cell carcinoma of the head and neck

    Boldrup, L., Bourdon, J-C., Coates, P. J., Sjostrom, B. & Nylander, K. 2007 In : European Journal of Cancer. 43, 3, p. 617-623, 7 p.

    Research output: Contribution to journal › Article

  229. Microbial biofilms in the human gastrointestinal tract

    Macfarlane, S. & Dillon, J. F. 2007 In : Journal of Applied Microbiology. 102, 5, p. 1187-1196, 10 p.

    Research output: Contribution to journal › Article

  230. Microbial colonization of the upper gastrointestinal tract in patients with Barrett's esophagus

    Macfarlane, S., Furrie, E., Macfarlane, G. T. & Dillon, J. F. 2007 In : Clinical Infectious Diseases. 45, 1, p. 29-38, 10 p.

    Research output: Contribution to journal › Article

  231. Reduction in antioxidant defenses may contribute to ochratoxin A toxicity and carcinogenicity

    Cavin, C., Delatour, T., Marin-Kuan, M., Holzhäuser, D., Higgins, L., Bezençon, C., Guignard, G., Junod, S., Richoz-Payot, J., Gremaud, E., Hayes, J. D., Nestler, S., Mantle, P. & Schilter, B. 2007 In : Toxicological Sciences. 96, 1, p. 30-9, 10 p.

    Research output: Contribution to journal › Article

  232. Risk and clinical implications of transformation of follicular lymphoma to diffuse large B-cell lymphoma

    Montoto, S., Davies, A. J., Matthews, J., Calaminici, M., Norton, A. J., Amess, J., Vinnicombe, S., Waters, R., Rohatiner, A. Z. S. & Lister, T. A. 2007 In : Journal of Clinical Oncology. 25, 17, p. 2426-33, 8 p.

    Research output: Contribution to journal › Article

  233. The genetic basis of tissue responses to ionizing radiation

    Lindsay, K. J., Coates, P. J., Lorimore, S. A. & Wright, E. G. 2007 In : British Journal of Radiology. 80 , Special issue 1, p. S2-S6, 5 p.

    Research output: Contribution to journal › Article

  234. TRPML cation channels regulate the specialized lysosomal compartment of vertebrate B-lymphocytes

    Song, Y., Dayalu, R., Matthews, S. A. & Scharenberg, A. M. 7-Dec-2006 In : European Journal of Cell Biology. 85, 12, p. 1253-64, 12 p.

    Research output: Contribution to journal › Article

  235. Regulating p73 isoforms in human tumours

    Coates, P. J. Dec-2006 In : Journal of Pathology. 210, 4, p. 385-9, 5 p.

    Research output: Contribution to journal › Editorial

  236. Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4

    Aberg, E., Perander, M., Johansen, B., Julien, C., Meloche, S., Keyse, S. M. & Seternes, O-M. 17-Nov-2006 In : Journal of Biological Chemistry. 281, 46, p. 35499-510, 12 p.

    Research output: Contribution to journal › Article

  237. Diverse physiological functions for dual-specificity MAP kinase phosphatases

    Dickinson, R. J. & Keyse, S. M. 15-Nov-2006 In : Journal of Cell Science. 119, P22, p. 4607-15, 9 p.

    Research output: Contribution to journal › Article

  238. Siglec-7 undergoes a major conformational change when complexed with the α(2,8)-disialylganglioside GT1b

    Attrill, H., Imamura, A., Sharma, R. S., Kiso, M., Crocker, P. R. & Van Aalten, D. M. F. 27-Oct-2006 In : Journal of Biological Chemistry. 281, 43, p. 32774-32783, 10 p.

    Research output: Contribution to journal › Article

  239. Genetic factors associated with the aetiology and treatment of colorectal cancer

    Wolf, C. R., Steele, R. J. C., Carey, F. A., Pratt, N. D., Bishop, D. T., Barrett, J. H., Forman, D. & Smith, G. 1-Sep-2006 In : Toxicology. 226, 1, p. 14-14, 1 p.

    Research output: Contribution to journal › Meeting abstract

  240. A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia

    Anensen, N., Oyan, A. M., Bourdon, J-C., Kalland, K. H., Bruserud, O. & Gjertsen, B. T. 1-Jul-2006 In : Clinical Cancer Research. 12, 13, p. 3985-3992, 8 p.

    Research output: Contribution to journal › Article

  241. Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver

    Mutch, D. M., Crespy, V., Clough, J., Henderson, C. J., Lariani, S., Mansourian, R., Moulin, J., Wolf, C. R. & Williamson, G. Jul-2006 In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 291, 1, p. G63-G72, 10 p.

    Research output: Contribution to journal › Article

  242. Inter- and intrasubject variation in cytoprotective gene expression in patients with psoriasis

    Smith, G., Hearn, R., Wolf, C. R., Ferguson, J. & Ibbotson, S. H. Jul-2006 In : British Journal of Dermatology. 155, 1, p. 254-254, 1 p., P26

    Research output: Contribution to journal › Meeting abstract

  243. Melanocortin 1 receptor genotype influences erythemal sensitivity and treatment response in patients undergoing psoralen plus ultraviolet A treatment

    Smith, G., Wilkie, M. J. V., Deeni, Y. Y., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Jul-2006 In : British Journal of Dermatology. 155, 1, p. 240-240, 1 p., O15

    Research output: Contribution to journal › Meeting abstract

  244. Dual beam fibre trap for Raman microspectroscopy of single cells

    Jess, P. R. T., Garces-Chavez, V., Smith, D., Mazilu, M., Paterson, L., Riches, A., Herrington, C. S., Sibbett, W. & Dholakia, K. 12-Jun-2006 In : Optics Express. 14, 12, p. 5779-5791, 13 p.

    Research output: Contribution to journal › Article

  245. p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress

    Murray-Zmijewski, F., Lane, D. & Bourdon, J-C. Jun-2006 In : Cell Death & Differentiation. 13, 6, p. 962-972, 11 p.

    Research output: Contribution to journal › Scientific review

  246. The role of serine/threonine kinases in T-cell activation

    Matthews, S. A. & Cantrell, D. A. Jun-2006 In : Current Opinion in Immunology. 18, 3, p. 314-320, 7 p.

    Research output: Contribution to journal › Article

  247. Untargeted effects of ionizing radiation: implications for radiation pathology

    Wright, E. G. & Coates, P. J. May-2006 In : Mutation Research. 597, 1-2, p. 119-32, 14 p.

    Research output: Contribution to journal › Scientific review

  248. Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

    Arlt, V. M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H. & Stiborova, M. 28-Mar-2006 In : Cancer Letters. 234, 2, p. 220-231, 12 p.

    Research output: Contribution to journal › Article

  249. The hepatic cytochrome P450 reductase null mouse as a tool to identify a successful candidate entity

    Henderson, C. J., Pass, G. J. & Wolf, C. R. 15-Mar-2006 In : Toxicology Letters. 162, 1, p. 111-117, 7 p.

    Research output: Contribution to journal › Article

  250. Chromosomal changes in colorectal adenomas: relationship to gene mutations and potential for clinical utility

    Leslie, A., Stewart, A., Baty, D. U., Mechan, D., McGreavey, L., Smith, G., Wolf, C. R., Sales, M., Pratt, N. R., Steele, R. J. C. & Carey, F. A. Feb-2006 In : Genes, Chromosomes and Cancer. 45, 2, p. 126-135, 10 p.

    Research output: Contribution to journal › Article

  251. The function of immunoglobulin A in immunity

    Woof, J. M. & Kerr, M. A. Jan-2006 In : Journal of Pathology. 208, 2, p. 270-282, 13 p.

    Research output: Contribution to journal › Article

  252. Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways

    Blackburn, A. C., Matthaei, K. I., Lim, C., Taylor, M. C., Cappello, J. Y., Hayes, J. D., Anders, M. W. & Board, P. G. 2006 In : Molecular Pharmacology. 69, 2, p. 650-7, 8 p.

    Research output: Contribution to journal › Article

  253. Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex

    McMahon, M., Thomas, N., Itoh, K., Yamamoto, M. & Hayes, J. D. 2006 In : Journal of Biological Chemistry. 281, 34, p. 24756-68, 13 p.

    Research output: Contribution to journal › Article

  254. Generation of a stable antioxidant response element-driven reporter gene cell line and its use to show redox-dependent activation of Nrf2 by cancer chemotherapeutic agents

    Wang, X. J., Hayes, J. D. & Wolf, C. R. 2006 In : Cancer Research. 66, 22, p. 10983-94, 12 p.

    Research output: Contribution to journal › Article

  255. Generation Scotland: the Scottish Family Health Study; a new resource for researching genes and heritability

    Smith, B. H. , Wolf, R. & 24 others Campbell, H., Blackwood, D., Connell, J., Connor, M., Deary, I. J., Dominiczak, A. F., Fitzpatrick, B., Ford, I., Jackson, C., Haddow, G., Kerr, S., Lindsay, R., McGilchrist, M., Morton, R., Murray, G., Palmer, C. N. A., Pell, J. P., Ralston, S. H., St Clair, D., Sullivan, F., Watt, G., Wright, A., Porteous, D. & Morris, A. D. 2006 In : BMC Medical Genetics. 7, 74

    Research output: Contribution to journal › Article

  256. Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer

    Hopman, A. H. N., Theelen, W., Hommelberg, P. P. H., Kamps, M. A. F., Herrington, C. S., Morrison, L. E., Speel, E-J. M., Smedts, F. & Ramaekers, F. C. S. 2006 In : Journal of Pathology. 210, 4, p. 412-419, 8 p.

    Research output: Contribution to journal › Article

  257. Identification of CYP2S1 ligands

    Dickmann, L. J., Deeni, Y., Smith, G. & Wolf, C. R. 2006 In : Drug Metabolism Reviews. 38, Suppl., p. 56-56, 1 p.

    Research output: Contribution to journal › Meeting abstract

  258. Identification of CYP2S1 ligands

    Dickmann, L. J., Deeni, Y., Smith, G. & Wolf, C. R. 2006

    Research output: Contribution to conference › Abstract

  259. Infection and disease: cause and cure

    Herrington, C. S. & Douek, D. C. 2006 In : Journal of Pathology. 208, 2, p. 131-133, 3 p.

    Research output: Contribution to journal › Editorial

  260. Interfering with leukocyte integrin activation: a novel concept in the development of anti-inflammatory drugs

    Hilden, T. J., Nurmi, S. M., Fagerholm, S. C. & Gahmberg, C. G. 2006 In : Annals of Medicine. 38, 7, p. 503-11, 9 p.

    Research output: Contribution to journal › Article

  261. Negative feedback predominates over cross-regulation to control ERK MAPK activity in response to FGF signalling in embryos

    Smith, T. G., Karlsson, M., Lunn, J. S., Eblaghie, M. C., Keenan, I. D., Farrell, E. R., Tickle, C., Storey, K. G. & Keyse, S. M. 2006 In : FEBS Letters. 580, 17, p. 4242-5, 4 p.

    Research output: Contribution to journal › Article

  262. p16, p14, p53, and cyclin D1 expression and HPV analysis in small cell carcinomas of the uterine cervix by Horn et al

    Herrington, C. S. 2006 In : International Journal of Gynecological Pathology. 25, 4, p. 408-408, 1 p.

    Research output: Contribution to journal › Letter

  263. Regulation of cutaneous drug-metabolizing enzymes and cytoprotective gene expression by topical drugs in human skin in vivo

    Smith, G., Ibbotson, S. H., Comrie, M. M., Dawe, R. S., Bryden, A., Ferguson, J. & Wolf, C. R. 2006 In : British Journal of Dermatology. 155, 2, p. 275-81, 7 p.

    Research output: Contribution to journal › Article

  264. Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases

    Karlsson, M., Mandl, M. & Keyse, S. M. 2006 In : Biochemical Society Transactions. 34, 5, p. 842-5, 4 p.

    Research output: Contribution to journal › Article

  265. The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer

    Hayes, J. D. & McMahon, M. 2006 In : Molecular Cell. 21, 6, p. 732-4, 3 p.

    Research output: Contribution to journal › Article

  266. The Pathological Society centenary

    Herrington, C. S. & Theobald, J. 2006 In : Journal of Pathology. 209, 3, p. 285-285, 1 p.

    Research output: Contribution to journal › Editorial

  267. Villoglandular adenocarcinoma of the cervix: clarity is needed on the histological definition for this difficult diagnosis

    Macdonald, R. D., Kirwan, J., Hayat, K., Herrington, C. S. & Shawki, H. 2006 In : Gynecologic Oncology. 100, 1, p. 192-194, 3 p.

    Research output: Contribution to journal › Article

  268. p53 isoforms can regulate p53 transcriptional activity

    Bourdon, J. C., Fernandes, K., Murray-Zmijewski, F., Liu, G., Diot, A., Xirodimas, D. P., Saville, M. K. & Lane, D. P. 15-Sep-2005 In : Genes & Development. 19, 18, p. 2122-2137, 16 p.

    Research output: Contribution to journal › Article

  269. The 'regulatory' β-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation

    Bjørling-Poulsen, M., Siehler, S., Wiesmüller, L., Meek, D., Niefind, K. & Issinger, O-G. 8-Sep-2005 In : Oncogene. 24, 40, p. 6194-6200, 7 p.

    Research output: Contribution to journal › Article

  270. HPV in situ hybridization: impact of different protocols on the detection of integrated HPV

    Hopman, A. H. N., Kamps, M. A., Smedts, F., Speel, E-J. M., Herrington, C. S. & Ramaekers, F. C. S. 20-Jun-2005 In : International Journal of Cancer. 115, 3, p. 419-428, 10 p.

    Research output: Contribution to journal › Article

  271. Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice

    Wang, X. J., Chamberlain, M., Vassieva, O., Henderson, C. J. & Wolf, C. R. 15-Jun-2005 In : Biochemical Journal. 388, 3, p. 857-867, 11 p.

    Research output: Contribution to journal › Article

  272. Phosphorylation of the acidic domain of Mdm2 by protein kinase CK2

    Allende-Vega, N., Dias, S., Milne, D. & Meek, D. Jun-2005 In : Molecular and Cellular Biochemistry. 274, 1-2, p. 85-90, 6 p.

    Research output: Contribution to journal › Article

  273. Role of hepatic cytochrome P450s in the pharmacokinetics and toxicity of cyclophosphamide: studies with the hepatic cytochrome P450 reductase null mouse

    Pass, G. J., Carrie, D., Boylan, M., Lorimore, S., Wright, E., Houston, B., Henderson, C. J. & Wolf, C. R. 15-May-2005 In : Cancer Research. 65, 10, p. 4211-4217, 7 p.

    Research output: Contribution to journal › Article

  274. HDM2 negatively affects the Chk2-mediated phosphorylation of p53

    Bjørling-Poulsen, M., Meek, D. & Issinger, O-G. 9-May-2005 In : FEBS Letters. 579, 12, p. 2604-2608, 5 p.

    Research output: Contribution to journal › Article

  275. Cloning and characterization of equine CD89 and identification of the CD89 gene in chimpanzees and rhesus macaques

    Morton, H. C., Pleass, R. J., Storset, A. K., Brandtzaeg, P. & Woof, J. M. May-2005 In : Immunology. 115, 1, p. 74-84, 11 p.

    Research output: Contribution to journal › Article

  276. Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H: quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols

    Arlt, V. M., Stiborova, M., Henderson, C. J., Osborne, M. R., Bieler, C. A., Frei, E., Martinek, V., Sopko, B., Wolf, C. R., Schmeiser, H. H. & Phillips, D. H. 1-Apr-2005 In : Cancer Research. 65, 7, p. 2644-2652, 9 p.

    Research output: Contribution to journal › Article

  277. A comparitive analysis of the scientific basis and visual appeal of seven dietary guideline graphics

    Kaufer-Horwitz, M., Valdes-Ramos, R., Willett, W. C., Anderson, A. & Solomons, N. W. Apr-2005 In : Nutrition Research. 25, 4, p. 335-347, 13 p.

    Research output: Contribution to journal › Article

  278. Feedback interactions between MKP3 and ERK MAP kinase control scleraxis expression and the specification of rib progenitors in the developing chick somite

    Smith, T. G., Sweetman, D., Patterson, M., Keyse, S. M. & Münsterberg, A. 15-Mar-2005 In : Development. 132, 6, p. 1305-14, 10 p.

    Research output: Contribution to journal › Article

  279. Effect of mutations in the human immunoglobulin A1 (IgA1) hinge on its susceptibility to cleavage by diverse bacterial IgA1 proteases

    Senior, B. W. & Woof, J. M. Mar-2005 In : Infection and Immunity. 73, 3, p. 1515-1522, 8 p.

    Research output: Contribution to journal › Article

  280. The murine Cyp1a1 gene is expressed in a restricted spatial and temporal pattern during embryonic development

    Campbell, S. J., Henderson, C. J., Anthony, D. C., Davidson, D., Clark, A. J. & Wolf, C. R. 18-Feb-2005 In : Journal of Biological Chemistry. 280, 7, p. 5828-5835, 8 p.

    Research output: Contribution to journal › Article

  281. Cell and tissue responses to genotoxic stress

    Coates, P. J., Lorimore, S. A. & Wright, E. G. Jan-2005 In : Journal of Pathology. 205, 2, p. 221-35, 15 p.

    Research output: Contribution to journal › Scientific review

  282. AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line

    Rencurel, F., Stenhouse, A., Hawley, S. A., Friedberg, T., Hardie, D. G., Sutherland, C. & Wolf, C. R. 2005 In : Journal of Biological Chemistry. 280, 6, p. 4367-4373, 7 p.

    Research output: Contribution to journal › Article

  283. Discriminating functional and non-functional p53 in human tumours by p53 and MDM2 immunohistochemistry

    Nenutil, R., Smardova, J., Pavlova, S., Hanzelkova, Z., Muller, P., Fabian, P., Hrstka, R., Janotova, P., Radina, M., Lane, D. P., Coates, P. J. & Vojtesek, B. 2005 In : Journal of Pathology. 207, 3, p. 251-259, 9 p.

    Research output: Contribution to journal › Article

  284. Disruption of the glutathione transferase Pi class genes

    Henderson, C. J. & Wolf, C. R. 2005 Methods in enzymology: gluthione transferases and gamma-glutamyl transpeptidases. Sies, H. & Packer, L. (eds.). San Diego: Academic Press, Vol. 401, p. 116-135 20 p.

    Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  285. Endogenous p63 acts as a survival factor for tumour cells of SCCHN origin

    Thurfjell, N., Coates, P. J., Vojtesek, B., Benham-Motlagh, P., Eisold, M. & Nylander, K. 2005 In : International Journal of Molecular Medicine. 16, 6, p. 1065-1070, 6 p.

    Research output: Contribution to journal › Article

  286. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome

    Katoh, Y., Iida, K., Kang, M-I., Kobayashi, A., Mizukami, M., Tong, K. I., McMahon, M., Hayes, J. D., Itoh, K. & Yamamoto, M. 2005 In : Archives of Biochemistry and Biophysics. 433, 2, p. 342-50, 9 p.

    Research output: Contribution to journal › Article

  287. Function and importance of p63 in normal oral mucosa and squamous cell carcinoma of the head and neck

    Thurfjell, N., Coates, P. J., Boldrup, L., Lindgren, B., Bäcklund, B., Uusitalo, T., Mahani, D., Dabelsteen, E., Dahlqvist, A., Sjöström, B., Roos, G., Vojtesek, B., Nenutil, R. & Nylander, K. 2005 In : Advances in Oto-Rhino-Laryngology. 62, p. 49-57, 9 p.

    Research output: Contribution to journal › Article

  288. Glutathione transferases

    Hayes, J. D., Flanagan, J. U. & Jowsey, I. R. 2005 In : Annual Review of Pharmacology and Toxicology. 45, p. 51-88, 38 p.

    Research output: Contribution to journal › Article

  289. Investigation of bacterial colonisation of the small bowel in patients with Barrett's oesophagus using 16S rRNA gene sequence analysis

    Macfarlane, S., Furrie, E., Macfarlane, G. T. & Dillon, J. F. 2005 In : Gut. 54, S2, p. A52-A52

    Research output: Contribution to journal › Meeting abstract

  290. Linking Smads and transcriptional activation

    Inman, G. J. 2005 In : Biochemical Journal. 386, Pt 1, p. e1-e3

    Research output: Contribution to journal › Article

  291. Mucosal immunoglobulins

    Woof, J. M. & Mestecky, J. 2005 In : Immunological Reviews. 206, p. 64-82, 19 p.

    Research output: Contribution to journal › Article

  292. Mutation and tissue microarray analysis of tumour suppressor genes and cell cycle-related proteins in colorectal cancer

    Robertson, K. E., Conlin, A., Miller, J., Smith, G., Steele, R. J. C., Wolf, C. R., Levison, D. A. & Carey, F. A. 2005 In : Journal of Pathology. 207, Suppl. 1, p. 43-43, 1 p.

    Research output: Contribution to journal › Meeting abstract

  293. Mutation and tissue microarray analysis of tumour suppressor genes and cell cycle-related proteins in colorectal cancer

    Robertson, K. E., Conlin, A., Miller, J., Smith, G., Steele, R. J. C., Wolf, C. R., Levison, D. A. & Carey, F. A. 2005

    Research output: Contribution to conference › Abstract

  294. Nephrectomy for renal tumour; dissection guide and dataset

    Fleming, S. & Griffiths, D. F. R. 2005 In : Journal of Clinical Pathology. 58, 1, p. 7-14, 8 p.

    Research output: Contribution to journal › Scientific review

  295. No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPAR[delta] and PPAR[gamma] act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma

    McGreavey, L. E., Turner, F., Smith, G., Boylan, K., Bishop, D. T., Forman, D., Wolf, C. R. & Barrett, J. H. 2005 In : Pharmacogenetics and Genomics. 15, 10, p. 713-721, 9 p.

    Research output: Contribution to journal › Article

  296. Nomenclature for mammalian soluble glutathione transferases

    Mannervik, B., Board, P. G., Hayes, J. D., Listowsky, I. & Pearson, W. R. 2005 In : Methods in Enzymology. 401, p. 1-8, 8 p.

    Research output: Contribution to journal › Article

  297. The pathology and management of endocervical glandular neoplasia

    El-Ghobashy, A. A., Shaaban, A. M., Herod, J. & Herrington, C. S. 2005 In : International Journal of Gynecological Cancer. 15, 4, p. 583-592, 10 p.

    Research output: Contribution to journal › Article

  298. Upregulation of heat shock protein 27 in metaplastic and neoplastic lesions of the endocervix

    El-Ghobashy, A. A., Shaaban, A. M., Innes, J., Prime, W. & Herrington, C. S. 2005 In : International Journal of Gynecological Cancer. 15, 3, p. 503-509, 7 p.

    Research output: Contribution to journal › Article

  299. Damaging and protective cell signalling in the untargeted effects of ionizing radiation

    Coates, P. J., Lorimore, S. A. & Wright, E. G. 2-Dec-2004 In : Mutation Research. 568, 1, p. 5-20, 16 p.

    Research output: Contribution to journal › Scientific review

  300. Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates

    McWalter, G. K., Higgins, L. G., McLellan, L. I., Henderson, C. J., Song, L., Thornalley, P. J., Itoh, K., Yamamoto, M. & Hayes, J. D. 1-Dec-2004 In : Journal of Nutrition. 134, 12, p. 3499S-3506S

    Research output: Contribution to journal › Article

  301. Plasma catecholamines and the counterregulatory responses to hypoglycemia in infants: a critical role for epinephrine and cortisol

    Jackson, L., Williams, F. L. R., Burchell, A., Coughtrie, M. W. H. & Hume, R. Dec-2004 In : Journal of Clinical Endocrinology & Metabolism. 89, 12, p. 6251-6256, 6 p.

    Research output: Contribution to journal › Article

  302. A novel site of AKT-mediated phosphorylation in the human MDM2 onco-protein

    Milne, D., Kampanis, P., Nicol, S., Dias, S., Campbell, D. G., Fuller-Pace, F. & Meek, D. 5-Nov-2004 In : FEBS Letters. 577, 1-2, p. 270-276, 7 p.

    Research output: Contribution to journal › Article

  303. Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer

    Turner, F., Smith, G., Sachse, C., Lightfoot, T., Garner, R. C., Wolf, C. R., Forman, D., Bishop, D. T., Barrett, J. H. & Colorectal Cancer Study Group 1-Nov-2004 In : International Journal of Cancer. 112, 2, p. 259-264, 6 p.

    Research output: Contribution to journal › Article

  304. Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal

    Karlsson, M., Mathers, J., Dickinson, R. J., Mandl, M. & Keyse, S. M. 1-Oct-2004 In : Journal of Biological Chemistry. 279, 40, p. 41882-91, 10 p.

    Research output: Contribution to journal › Article

  305. Comparison of compositions and metabolic activities of fecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects

    Woodmansey, E. J., McMurdo, M. E. T., Macfarlane, G. T. & Macfarlane, S. Oct-2004 In : Applied and Environmental Microbiology. 70, 10, p. 6113-6122, 10 p.

    Research output: Contribution to journal › Article

  306. P marks the spot: site-specific integrin phosphorylation regulates molecular interactions

    Fagerholm, S. C., Hilden, T. J. & Gahmberg, C. G. Sep-2004 In : Trends in Biochemical Sciences. 29, 9, p. 504-12, 9 p.

    Research output: Contribution to journal › Article

  307. Regulation of cytochrome P450 CYP2S1 in human skin by UVR and topical drugs used to treat psoriasis

    Smith, G., Deeni, Y. Y., Dawe, R. S., Evans, A. T., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Aug-2004 In : Drug Metabolism Reviews. 36, Supplement 1, p. 181-181, 1 p., 363

    Research output: Contribution to journal › Meeting abstract

  308. Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

    Xirodimas, D. P., Saville, M. K., Bourdon, J. C., Hay, R. T. & Lane, D. P. 9-Jul-2004 In : Cell. 118, 1, p. 83-97, 15 p.

    Research output: Contribution to journal › Article

  309. Characterization of bacterial communities in feces from healthy elderly volunteers and hospitalized elderly patients by using real-time PCR and effects of antibiotic treatment on the fecal microbiota

    Bartosch, S., Fite, A., Macfarlane, G. T. & McMurdo, M. E. T. Jun-2004 In : Applied and Environmental Microbiology. 70, 6, p. 3575-81, 7 p.

    Research output: Contribution to journal › Article

  310. Induction of tetrasomy by human papillomavirus type 16 E7 protein is independent of pRb binding and disruption of differentiation

    Southern, S. A., Lewis, M. H. & Herrington, C. S. 17-May-2004 In : British Journal of Cancer. 90, 10, p. 1949-1954, 6 p.

    Research output: Contribution to journal › Article

  311. Solution structure determination of monomeric human IgA2 by X-ray and neutron scattering, analytical ultracentrifugation and constrained modelling: a comparison with monomeric human IgA1

    Furtado, P. B., Whitty, P. W., Robertson, A., Eaton, J. T., Almogren, A., Kerr, M. A., Woof, J. M. & Perkins, S. J. 14-May-2004 In : Journal of Molecular Biology. 338, 5, p. 921-941, 21 p.

    Research output: Contribution to journal › Article

  312. Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa

    Thomson, R. E., Bigley, A. L., Foster, J. R., Jowsey, I. R., Elcombe, C. R., Orton, T. C. & Hayes, J. D. May-2004 In : Journal of Histochemistry & Cytochemistry. 52, 5, p. 653-662, 10 p.

    Research output: Contribution to journal › Article

  313. Acute renal failure associated with Gemella haemolysans pneumonia

    Eisenhut, M., Jones, C., Hughes, D., Herrington, S. & Kokai, G. Apr-2004 In : Pediatric Nephrology. 19, 4, p. 448-450, 3 p.

    Research output: Contribution to journal › Article

  314. Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1

    Burch, L. R., Scott, M., Pohler, E., Meek, D. & Hupp, T. 12-Mar-2004 In : Journal of Molecular Biology. 337, 1, p. 115-128, 14 p.

    Research output: Contribution to journal › Article

  315. Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure

    Jetter, A., Kinzig-Schippers, M., Illauer, M., Hermann, R., Erb, K., Borlak, J., Wolf, H., Smith, G., Cascorbi, I., Sorgel, F. & Fuhr, U. Mar-2004 In : European Journal of Clinical Pharmacology. 60, 1, p. 17-21, 5 p.

    Research output: Contribution to journal › Article

  316. Human antibody-Fc receptor interactions illuminated by crystal structures

    Woof, J. M. & Burton, D. R. Feb-2004 In : Nature Reviews Immunology. 4, 2, p. 89-99, 11 p.

    Research output: Contribution to journal › Article

  317. Expression of PAX 3 alternatively spliced transcripts and identification of two new isoforms in human tumors of neural crest origin

    Parker, C. J., Shawcross, S. G., Li, H., Wang, Q-Y., Herrington, C. S., Kumar, S., MacKie, R. M., Prime, W., Rennie, I. G., Sisley, K. & Kumar, P. 10-Jan-2004 In : International Journal of Cancer. 108, 2, p. 314-320, 7 p.

    Research output: Contribution to journal › Article

  318. Primary cultured neurons devoid of cellular prion display lower responsiveness to Staurosporine through the control of p53 at both transcriptional and post-transcriptional levels

    Paitel, E., Sunyach, C., da Costa, C. A., Bourdon, J-C., Vincent, B. & Checler, F. 2-Jan-2004 In : Journal of Biological Chemistry. 279, 1, p. 612-618, 7 p.

    Research output: Contribution to journal › Article

  319. A retrospective clinical audit of cervical smears reported as 'glandular neoplasia'

    Kirwan, J. M., Herrington, C. S., Smith, P. A., Turnbull, L. S. & Herod, J. J. O. 2004 In : Cytopathology : Official Journal of the British Society for Clinical Cytology. 15, 4, p. 188-194, 7 p.

    Research output: Contribution to journal › Article

  320. Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice

    Goldring, C. E. P., Kitteringham, N. R., Elsby, R., Randle, L. E., Clement, Y. N., Williams, D. P., McMahon, M., Hayes, J. D., Itoh, K., Yamamoto, M. & Park, B. K. 2004 In : Hepatology. 39, 5, p. 1267-76, 10 p.

    Research output: Contribution to journal › Article

  321. Antioxidant and cytoprotective responses to redox stress

    Mathers, J., Fraser, J. A., McMahon, M., Saunders, R. D. C., Hayes, J. D. & McLellan, L. I. 2004 In : Biochemical Society Symposium. 71, p. 157-76, 20 p.

    Research output: Contribution to journal › Article

  322. Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck

    Thurfjell, N., Coates, P. J., Uusitalo, T., Mahani, D., Dabelsteen, E., Dahlqvist, A., Sjöström, B., Roos, G. & Nylander, K. 2004 In : International Journal of Oncology. 25, 1, p. 27-35, 9 p.

    Research output: Contribution to journal › Article

  323. Confident, fearful and hopeless cooks: Findings from the development of a food-skills initiative

    Stead, M., Caraher, M., Wrieden, W., Longbottom, P., Valentine, K. & Anderson, A. 2004 In : British Food Journal. 106, 4, p. 274-287, 14 p.

    Research output: Contribution to journal › Article

  324. Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors

    Nioi, P. & Hayes, J. D. 2004 In : Mutation Research. 555, 1-2, p. 149-71, 23 p.

    Research output: Contribution to journal › Article

  325. Initial characterization of a rat model of diabetic nephropathy

    Nobrega, M. A., Fleming, S., Roman, R. J., Shiozawa, M., Schlick, N., Lazar, J. & Jacob, H. J. 2004 In : Diabetes. 53, 3, p. 735-42, 8 p.

    Research output: Contribution to journal › Article

  326. Molecular markers for the prediction of progression of CIN lesions

    Gray, L. J. & Herrington, C. S. 2004 In : International Journal of Gynecological Pathology. 23, 2, p. 95-96, 2 p.

    Research output: Contribution to journal › Editorial

  327. No association of polymorphisms in CYP17, CYP19, and HSD17-B1 with plasma estradiol concentrations in 1,090 British women

    Travis, R. C., Churchman, M., Edwards, S. A., Smith, G., Verkasalo, P. K., Wolf, C. R., Wolf, H. & Key, T. J. 2004 In : Cancer Epidemiology, Biomarkers & Prevention. 13, 12, p. 2282-4, 3 p.

    Research output: Contribution to journal › Article

  328. Non spiral and spiral (helical) flow patterns in stenoses. In vitro observations using spin and gradient echo magnetic resonance imaging (MRI) and computational fluid dynamic modeling

    Stonebridge, P. A., Buckley, C., Thompson, A., Dick, J., Hunter, G., Chudek, J. A., Houston, J. G. & Belch, J. J. F. 2004 In : International Angiology. 23, 3, p. 276-283, 8 p.

    Research output: Contribution to journal › Article

  329. Overexpression of cyclins A and B as markers of neoplastic glandular lesions of the cervix

    El-Ghobashy, A. A., Shaaban, A. M., Herod, J., Innes, J., Prime, W. & Herrington, C. S. 2004 In : Gynecologic Oncology. 92, 2, p. 628-634, 7 p.

    Research output: Contribution to journal › Article

  330. P16INK4a and p14ARF tumor suppressor genes are commonly inactivated in cutaneous squamous cell carcinoma

    Brown, V. L., Harwood, C. A., Crook, T., Cronin, J. G., Kelsell, D. P. & Proby, C. M. 2004 In : Journal of Investigative Dermatology. 122, 5, p. 1284-1292, 9 p.

    Research output: Contribution to journal › Article

  331. Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron

    McMahon, M., Thomas, N., Itoh, K., Yamamoto, M. & Hayes, J. D. 2004 In : Journal of Biological Chemistry. 279, 30, p. 31556-67, 12 p.

    Research output: Contribution to journal › Article

  332. Retransplantation in Alport post-transplant anti-GBM disease

    Browne, G., Brown, P. A. J., Tomson, C. R. V., Fleming, S., Allen, A., Herriot, R., Pusey, C. D., Rees, A. J. & Turner, A. N. 2004 In : Kidney International. 65, 2, p. 675-81, 7 p.

    Research output: Contribution to journal › Article

  333. The Journal of Pathology moves forward

    Herrington, C. S., Theobald, J. J., Newton, S. D. & Smart, M. A. 2004 In : Journal of Pathology. 204, 5, p. 507-509, 3 p.

    Research output: Contribution to journal › Editorial

  334. The p53 response to DNA damage

    Meek, D. W. 2004 In : DNA Repair. 3, 8-9, p. 1049-1056, 8 p.

    Research output: Contribution to journal › Scientific review

  335. The role of the renin-angiotensin system in malignant vascular injury affecting the systemic and cerebral circulations

    Collidge, T. A., Lammie, G. A., Fleming, S. & Mullins, J. J. 2004 In : Progress in Biophysics and Molecular Biology. 84, 2-3, p. 301-19, 19 p.

    Research output: Contribution to journal › Article

  336. Use of the nested reverse transcription-polymerase chain reaction for the detection of human papillornavirus 16 E6 transcriptional activity in cervical cancer: a technical perspective

    Moodley, M., Moodley, J., Herrington, C. S., Sewart, S. & Chetty, R. 2004 In : European Journal of Gynaecological Oncology. 25, 1, p. 51-54, 4 p.

    Research output: Contribution to journal › Article

  337. Wild-type p53 activates SAP expression in lymphoid cells

    Nagy, N., Takahara, M., Nishikawa, J., Bourdon, J. C., Kis, L. L., Klein, G. & Klein, E. 2004 In : Oncogene. 23, 53, p. 8563-8570, 8 p.

    Research output: Contribution to journal › Article

  338. Posttranslational modification of MDM2

    Meek, D. W. & Knippschild, U. Dec-2003 In : Molecular Cancer Research. 1, 14, p. 1017-26, 10 p.

    Research output: Contribution to journal › Article

  339. Adenosine deaminase, a key enzyme in DNA precursors control, is a new p73 target

    Tullo, A., Mastropasqua, G., Bourdon, J. C., Centonze, P., Gostissa, M., Costanzo, A., Levrero, M., Del Sal, G., Saccone, C. & Sbisa, E. 27-Nov-2003 In : Oncogene. 22, 54, p. 8738-8748, 11 p.

    Research output: Contribution to journal › Article

  340. A woman with renal failure, ureteric obstruction and vasculitic rash

    Alexander, J. L., Rustom, R., Herrington, C. S., Kingston, R. E. & Bone, J. M. Nov-2003 In : Nephrology Dialysis Transplantation. 18, 11, p. 2439-2441, 3 p.

    Research output: Contribution to journal › Article

  341. Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma

    Shekouh, A. R., Thompson, C. C., Prime, W., Campbell, F., Hamlett, J., Herrington, C. S., Lemoine, N. R., Crnogorac-Jurcevic, T., Buechler, M. W., Friess, H., Neoptolemos, J. P., Pennington, S. R. & Costello, E. Oct-2003 In : Proteomics. 3, 10, p. 1988-2001, 14 p.

    Research output: Contribution to journal › Article

  342. Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis

    Otto, D. M. E., Henderson, C. J., Carrie, D., Davey, M., Gundersen, T. E., Blomhoff, R., Adams, R. H., Tickle, C. & Wolf, C. R. Sep-2003 In : Molecular and Cellular Biology. 23, 17, p. 6103-6116, 14 p.

    Research output: Contribution to journal › Article

  343. Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents

    Sherratt, P. J., McLellan, L. I. & Hayes, J. D. 1-Jul-2003 In : Biochemical Pharmacology. 66, 1, p. 51-61, 11 p.

    Research output: Contribution to journal › Article

  344. Limited role of charge matching in the interaction of human immunoglobulin A with the immunoglobulin A Fc receptor (Fc α RI) CD89

    Pleass, R. J., Dehal, P. K., Lewis, M. J. & Woof, J. M. Jul-2003 In : Immunology. 109, 3, p. 331-335, 5 p.

    Research output: Contribution to journal › Article

  345. Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi

    Elsby, R., Kitteringham, N. R., Goldring, C. E., Lovatt, C. A., Chamberlain, M., Henderson, C. J., Wolf, C. R. & Park, B. K. 20-Jun-2003 In : Journal of Biological Chemistry. 278, 25, p. 22243-22249, 7 p.

    Research output: Contribution to journal › Article

  346. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

    McMahon, M., Itoh, K., Yamamoto, M. & Hayes, J. D. 13-Jun-2003 In : Journal of Biological Chemistry. 278, 24, p. 21592-21600, 9 p.

    Research output: Contribution to journal › Article

  347. Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos

    Eblaghie, M. C., Lunn, J. S., Dickinson, R. J., Münsterberg, A. E., Sanz-Ezquerro, J. J., Farrell, E. R., Mathers, J., Keyse, S. M., Storey, K. & Tickle, C. Jun-2003 In : Current Biology. 13, 12, p. 1009-18, 10 p.

    Research output: Contribution to journal › Article

  348. Cytochrome P450 CYP2S1 expression in human skin: individuality in regulation by therapeutic agents for psoriasis and other skin diseases

    Smith, G., Deeni, Y. Y., Dawe, R. S., Comrie, M. M., Wolf, C. R., Ferguson, J. & Ibbotson, S. H. Apr-2003 In : British Journal of Dermatology. 148, 4, p. 853-853, 1 p., O16

    Research output: Contribution to journal › Meeting abstract

  349. Precision-cut tissue slices from transgenic mice as an in vitro toxicology system

    Catania, J. M., Parrish, A. R., Kirkpatrick, D. S., Chitkara, M., Bowden, G. T., Henderson, C. J., Wolf, C. R., Clark, A. J., Brendel, K., Fisher, R. L. & Gandolfi, A. J. Apr-2003 In : Toxicology in Vitro. 17, 2, p. 201-205, 5 p.

    Research output: Contribution to journal › Article

  350. Amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by streptococcal IgA1 proteases

    Batten, M. R., Senior, B. W., Kilian, M. & Woof, J. M. Mar-2003 In : Infection and Immunity. 71, 3, p. 1462-1469, 8 p.

    Research output: Contribution to journal › Article

  351. Neural differentiation of mouse embryonic stem cells

    Stavridis, M. P. & Smith, A. G. Feb-2003 In : Biochemical Society Transactions. 31, Pt 1, p. 45-49, 5 p.

    Research output: Contribution to journal › Scientific review

  352. Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver

    Kitteringham, N. R., Powell, H., Hamlett, J., Hamlett, J., Lovatt, C., Elsby, R., Henderson, C. J., Wolf, C. R., Pennington, S. R. & Park, B. K. Feb-2003 In : Proteomics. 3, 2, p. 191-207, 17 p.

    Research output: Contribution to journal › Article

  353. Alteration of glutathione S-transferase levels in Barrett's metaplasia compared to normal oesophageal epithelium

    Cobbe, S. C., Scobie, G. C., Pohler, E., Hayes, J. D., Kernohan, N. M. & Dillon, J. F. 2003 In : European Journal of Gastroenterology & Hepatology. 15, 1, p. 41-47, 7 p.

    Research output: Contribution to journal › Article

  354. Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase

    Jowsey, I. R., Thomson, R. E., Orton, T. C., Elcombe, C. R. & Hayes, J. D. 2003 In : Biochemical Journal. 373, Pt 2, p. 559-69, 11 p.

    Research output: Contribution to journal › Article

  355. CD10 and calretinin staining of endocervical glandular lesions, endocervical stroma and endometrioid adenocarcinomas of the uterine corpus: CD10 positivity is characteristic of, but not specific for, mesonephric lesions and is not specific for endometrial stroma

    McCluggage, W. G., Oliva, E., Herrington, C. S., McBride, H. & Young, R. H. 2003 In : Histopathology. 43, 2, p. 144-150, 7 p.

    Research output: Contribution to journal › Article

  356. Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene promoter

    Ellis, E. M., Slattery, C. M. & Hayes, J. D. 2003 In : Carcinogenesis. 24, 4, p. 727-37, 11 p.

    Research output: Contribution to journal › Article

  357. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

    Ying, Q-L., Stavridis, M., Griffiths, D., Li, M. & Smith, A. 2003 In : Nature Biotechnology. 21, 2, p. 183-6, 4 p.

    Research output: Contribution to journal › Article

  358. Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases

    Smith, G., Wolf, C. R., Deeni, Y. Y., Dawe, R. S., Evans, A. T., Comrie, M. M., Ferguson, J. & Ibbotson, S. H. 2003 In : Lancet. 361, 9366, p. 1336-1343, 8 p.

    Research output: Contribution to journal › Article

  359. Differential expression of p73alpha in normal ectocervical epithelium, cervical intraepithelial neoplasia, and invasive squamous cell carcinoma

    Nenutil, R., Ceskova, P., Coates, P. J., Nylander, K. & Vojtesek, B. 2003 In : International Journal of Gynecological Pathology. 22, 4, p. 386-392, 7 p.

    Research output: Contribution to journal › Article

  360. Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element

    Jowsey, I. R., Jiang, Q., Itoh, K., Yamamoto, M. & Hayes, J. D. 2003 In : Molecular Pharmacology. 64, 5, p. 1018-28, 11 p.

    Research output: Contribution to journal › Article

  361. Expression of the murine glutathione S-transferase α3 (GSTA3) subunit is markedly induced during adipocyte differentiation: activation of the GSTA3 gene promoter by the pro-adipogenic eicosanoid 15-deoxy-Δ12,14-prostaglandin J2

    Jowsey, I. R., Smith, S. A. & Hayes, J. D. 2003 In : Biochemical and Biophysical Research Communications. 312, 4, p. 1226-35, 10 p.

    Research output: Contribution to journal › Article

  362. Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency

    Alam, N. A. , Rowan, A. J. , Wortham, N. C. , Pollard, P. J. , Mitchell, M. , Tyrer, J. P. , Barclay, E. , Calonje, E. , Manek, S. , Adams, S. J. , Bowers, P. W. , Burrows, N. P. , Charles-Holmes, R. , Cook, L. J. , Daly, B. M. , Ford, G. P. , Fuller, L. C. , Hadfield-Jones, S. E. , Hardwick, N. , Highet, A. S. & 22 others Keefe, M., MacDonald-Hull, S. P., Potts, E. D. A., Crone, M., Wilkinson, S., Camacho-Martinez, F., Jablonska, S., Ratnavel, R., MacDonald, A., Mann, R. J., Grice, K., Guillet, G., Lewis-Jones, M. S., McGrath, H., Seukeran, D. C., Morrison, P. J., Fleming, S., Rahman, S., Kelsell, D., Leigh, I., Olpin, S. & Tomlinson, I. P. M. 2003 In : Human Molecular Genetics. 12, 11, p. 1241-52, 12 p.

    Research output: Contribution to journal › Article

  363. Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

    Nioi, P., McMahon, M., Itoh, K., Yamamoto, M. & Hayes, J. D. 2003 In : Biochemical Journal. 374, Pt 2, p. 337-48, 12 p.

    Research output: Contribution to journal › Article

  364. Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer

    Barrett, J. H., Smith, G., Waxman, R., Gooderham, N., Lightfoot, T., Garner, R. C., Augustsson, K., Wolf, C. R., Bishop, D. T. & Forman, D. 2003 In : Carcinogenesis. 24, 2, p. 275-282, 8 p.

    Research output: Contribution to journal › Article

  365. Knockout mice in xenobiotic metabolism

    Henderson, C. J., Otto, D. M. E., McLaren, A. W., Carrie, D. & Wolf, C. R. 2003 In : Drug Metabolism Reviews. 35, 4, p. 385-392, 8 p.

    Research output: Contribution to journal › Article

  366. p53: 25 years of research and more questions to answer

    Bourdon, J. C., De Laurenzi, V., Melino, G. & Lane, D. 2003 In : Cell Death & Differentiation. 10, 4, p. 397-399, 3 p.

    Research output: Contribution to journal › Editorial

  367. Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism

    Sachse, C., Bhambra, U., Smith, G., Lightfoot, T. J., Barrett, J. H., Scollay, J., Garner, R. C., Boobis, A. R., Wolf, C. R., Gooderham, N. J. & Colorectal Cancer Study Group 2003 In : British Journal of Clinical Pharmacology. 55, 1, p. 68-76, 9 p.

    Research output: Contribution to journal › Article

  368. Prostaglandin D2 synthase enzymes and PPARγ are co-expressed in mouse 3T3-L1 adipocytes and human tissues

    Jowsey, I. R., Murdock, P. R., Moore, G. B. T., Murphy, G. J., Smith, S. A. & Hayes, J. D. 2003 In : Prostaglandins & Other Lipid Mediators. 70, 3-4, p. 267-84, 18 p.

    Research output: Contribution to journal › Article

  369. Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation

    Lorimore, S. A., Coates, P. J. & Wright, E. G. 2003 In : Oncogene. 22, 45, p. 7058-69, 12 p.

    Research output: Contribution to journal › Scientific review

  370. Radiation-induced genomic instability in immortalized haemopoietic stem cells

    McIlrath, J., Lorimore, S. A., Coates, P. J. & Wright, E. G. 2003 In : International Journal of Radiation Biology. 79, 1, p. 27-34, 8 p.

    Research output: Contribution to journal › Article

  371. Re: The association of viral infection and chronic allograft nephropathy with graft dysfunction after renal transplantation

    Tong, C. Y. W., Muir, P., Bakran, A., Peiris, J. S. M. & Herrington, C. S. 2003 In : Transplantation. 76, 3, p. 621-622, 2 p.

    Research output: Contribution to journal › Letter

  372. Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice

    Aubert, J., Stavridis, M. P., Tweedie, S., O'Reilly, M., Vierlinger, K., Li, M., Ghazal, P., Pratt, T., Mason, J. O., Roy, D. & Smith, A. 2003 In : Proceedings of the National Academy of Sciences of the United States of America. 100 , Suppl. 1, p. 11836-11841, 6 p.

    Research output: Contribution to journal › Article

  373. The interaction between steroid hormones, human papillomavirus type 16, E6 oncogene expression, and cervical cancer

    Moodley, M., Sewart, S., Herrington, C. S., Chetty, R., Pegoraro, R. & Moodley, J. 2003 In : International Journal of Gynecological Cancer. 13, 6, p. 834-842, 9 p.

    Research output: Contribution to journal › Article

  374. The role of steroid contraceptive hormones in the pathogenesis of invasive cervical cancer: a review

    Moodley, M., Moodley, J., Chetty, R. & Herrington, C. S. 2003 In : International Journal of Gynecological Cancer. 13, 2, p. 103-110, 8 p.

    Research output: Contribution to journal › Article

  375. The wt1-heterozygous mouse: a model to study the development of glomerular sclerosis

    Menke, A. L., IJpenberg, A., Fleming, S., Ross, A., Medine, C. N., Patek, C. E., Spraggon, L., Hughes, J., Clarke, A. R. & Hastie, N. D. 2003 In : Journal of Pathology. 200, 5, p. 667-74, 8 p.

    Research output: Contribution to journal › Article

  376. The yeast two-hybrid system for identifying protein-protein interactions

    Coates, P. J. & Hall, P. A. 2003 In : Journal of Pathology. 199, 1, p. 4-7, 4 p.

    Research output: Contribution to journal › Editorial

  377. Topical coal tar and all-trans retinoic acid modulate drug metabolising gene expression in human skin in vivo

    Ibbotson, S. H., Smith, G., Sawe, R. S., Comrie, M. M., Bryden, A., Wolf, C. E. & Ferguson, J. 2003 In : British Journal of Dermatology. 148, 4, p. 861-861, 1 p., P15

    Research output: Contribution to journal › Meeting abstract

  378. Topical coal tar and all-trans retinoic acid modulate drug metabolising gene expression in human skin in vivo

    Ibbotson, S. H., Smith, G., Sawe, R. S., Comrie, M. M., Bryden, A., Wolf, C. E. & Ferguson, J. 2003

    Research output: Contribution to conference › Poster

  379. Stoichiometry of active smad-transcription factor complexes on DNA

    Inman, G. J. & Hill, C. S. 27-Dec-2002 In : Journal of Biological Chemistry. 277, 52, p. 51008-16, 9 p.

    Research output: Contribution to journal › Article

  380. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

    Sachse, C., Smith, G., Wilkie, M. J. V., Barrett, J. H., Waxman, R., Sullivan, F., Forman, D., Bishop, D. T., Wolf, C. R. & Colorectal Cancer Study Group Nov-2002 In : Carcinogenesis. 23, 11, p. 1839-49, 11 p.

    Research output: Contribution to journal › Article

  381. p16(INK4a) immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia

    Klaes, R., Benner, A., Friedrich, T., Ridder, R., Herrington, S., Jenkins, D., Kurman, R. J., Schmidt, D., Stoler, M. & Doeberitz, M. . K. Nov-2002 In : American Journal of Surgical Pathology. 26, 11, p. 1389-1399, 11 p.

    Research output: Contribution to journal › Article

  382. Both binding and activation of p38 mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress

    Seternes, O. M., Johansen, B., Hegge, B., Johannessen, M., Keyse, S. M. & Moens, U. Oct-2002 In : Molecular and Cellular Biology. 22, 20, p. 6931-45, 15 p.

    Research output: Contribution to journal › Article

  383. Centrosomal anchoring of the protein kinase CK1δ mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450

    Sillibourne, J., Milne, D. M., Takahashi, M., Ono, Y. & Meek, D. W. 27-Sep-2002 In : Journal of Molecular Biology. 322, 4, p. 785-97, 13 p.

    Research output: Contribution to journal › Article

  384. YIL113w encodes a functional dual-specificity protein phosphatase which specifically interacts with and inactivates the Slt2/Mpk1p MAP kinase in S. cerevisiae

    Collister, M., Didmon, M. P., MacIsaac, F., Stark, M. J., MacDonald, N. Q. & Keyse, S. M. 11-Sep-2002 In : FEBS Letters. 527, 1-3, p. 186-92, 7 p.

    Research output: Contribution to journal › Article

  385. Expression and regulation of cytoprotective genes by ultraviolet radiation in skin of patients with psoriasis

    Smith, G., Dawe, R. S., Evans, A. T., Comrie, M. M., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Sep-2002 In : Journal of Investigative Dermatology. 119, 3, p. 740-740, 1 p., 166

    Research output: Contribution to journal › Meeting abstract

  386. Activation of leukocyte β2-integrins

    Gahmberg, C. G. & Fagerholm, S. Aug-2002 In : Vox Sanguinis. 83, S1, p. 355-358, 4 p.

    Research output: Contribution to journal › Article

  387. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

    Inman, G. J., Nicolás, F. J., Callahan, J. F., Harling, J. D., Gaster, L. M., Reith, A. D., Laping, N. J. & Hill, C. S. 1-Jul-2002 In : Molecular Pharmacology. 62, 1, p. 65-74, 10 p.

    Research output: Contribution to journal › Article

  388. Lck tyrosine kinase is important for activation of the CD11a/CD18-integrins in human T lymphocytes

    Fagerholm, S., Hilden, T. J. & Gahmberg, C. G. Jun-2002 In : European Journal of Immunology. 32, 6, p. 1670-1678, 9 p.

    Research output: Contribution to journal › Article

  389. Self testing for human papillomaviruses

    Herrington, C. S. Jun-2002 In : Journal of Clinical Pathology. 55, 6, p. 408-409, 2 p.

    Research output: Contribution to journal › Editorial

  390. Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase

    Dickinson, R. J., Williams, D. J., Slack, D. N., Williamson, J., Seternes, O-M. & Keyse, S. M. 15-May-2002 In : Biochemical Journal. 364, 1, p. 145-55, 11 p.

    Research output: Contribution to journal › Article

  391. Expression of the ERK-specific MAP kinase phosphatase PYST1/MKP3 in mouse embryos during morphogenesis and early organogenesis

    Dickinson, R. J., Eblaghie, M. C., Keyse, S. M. & Morriss-Kay, G. M. May-2002 In : Mechanisms of Development. 113, 2, p. 193-6, 4 p.

    Research output: Contribution to journal › Article

  392. Dietary interventions in Finland, Norway and Sweden: nutrition policies and strategies

    Roos, G., Lean, M. & Anderson, A. Apr-2002 In : Journal of Human Nutrition and Dietetics. 15, 2, p. 99-110, 12 p.

    Research output: Contribution to journal › Article

  393. Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes

    Fagerholm, S., Morrice, N., Gahmberg, C. G. & Cohen, P. 18-Jan-2002 In : Journal of Biological Chemistry. 277, 3, p. 1728-1738, 11 p.

    Research output: Contribution to journal › Article

  394. A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 in regulating gastrulation movements

    Howell, M., Inman, G. J. & Hill, C. S. 2002 In : Development. 129, 12, p. 2823-2834, 12 p.

    Research output: Contribution to journal › Article

  395. Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury

    Mayer, N. J., Forsyth, A., Kantachuvesiri, S., Mullins, J. J. & Fleming, S. 2002 In : Molecular Pathology. 55, 1, p. 29-33, 5 p.

    Research output: Contribution to journal › Article

  396. Chromosomal abnormality and gene mutation in sporadic colorectal cancer

    Leslie, A., Smith, G., Pratt, N. R., Carey, F. A., Wolf, C. R. & Steele, R. J. C. 2002 In : British Journal of Surgery. 89, 5, p. 663-664, 2 p.

    Research output: Contribution to journal › Meeting abstract

  397. Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif

    Randall, R. A., Germain, S., Inman, G. J., Bates, P. A. & Hill, C. S. 2002 In : EMBO Journal. 21, 1-2, p. 145-156, 12 p.

    Research output: Contribution to journal › Article

  398. Direct comparison of the nature of mouse and human GST T1-1 and the implications on dichloromethane carcinogenicity

    Sherratt, P. J., Williams, S., Foster, J., Kernohan, N., Green, T. & Hayes, J. D. 2002 In : Toxicology and Applied Pharmacology. 179, 2, p. 89-97, 9 p.

    Research output: Contribution to journal › Article

  399. Factors influencing the cellular accumulation of SN-38 and camptothecin

    Cummings, J., Boyd, G., Macpherson, J. S., Wolf, H., Smith, G., Smyth, J. F. & Jodrell, D. I. 2002 In : Cancer Chemotherapy and Pharmacology. 49, 3, p. 194-200, 7 p.

    Research output: Contribution to journal › Article

  400. Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

    Chanas, S. A., Jiang, Q., McMahon, M., McWalter, G. K., McLellan, L. I., Elcombe, C. R., Henderson, C. J., Wolf, C. R., Moffat, G. J., Itoh, K., Yamamoto, M. & Hayes, J. D. 2002 In : Biochemical Journal. 365, Pt 2, p. 405-16, 12 p.

    Research output: Contribution to journal › Article

  401. Markers of senescence?

    Coates, P. J. 2002 In : Journal of Pathology. 196, 4, p. 371-373, 3 p.

    Research output: Contribution to journal › Article

  402. Novel homodimeric and heterodimeric rat g-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins

    Kelly, V. P., Sherratt, P. J., Crouch, D. H. & Hayes, J. D. 2002 In : Biochemical Journal. 366, Pt 3, p. 847-61, 15 p.

    Research output: Contribution to journal › Article

  403. Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

    Inman, G. J., Nicolás, F. J. & Hill, C. S. 2002 In : Molecular Cell. 10, 2, p. 283-294, 12 p.

    Research output: Contribution to journal › Article

  404. p53 Induction: phosphorylation sites cooperate in regulating

    Meek, D. W. 2002 In : Cancer Biology & Therapy. 1, 3, p. 284-286, 3 p.

    Research output: Contribution to journal › Comment/debate

  405. p53 mutation rate in oesophageal carcinoma is higher than generally accepted

    Oglesby, S. D., Warbrick, E., Johnston, D. A., Dillon, J. F., Munro, A. J., Hupp, T. R. & Thompson, A. M. 2002 In : British Journal of Cancer. 86, S1, p. S47-S47, 1 p.

    Research output: Contribution to journal › Meeting abstract

  406. p53 mutations in oesopahgeal adenocarcinoma are common and are associated with disease response

    Oglesby, S. D., Warbrick, E., Johnston, D. A., Dillon, J. F., Munro, A. J., Hupp, T. R. & Thompson, A. M. 2002 In : Gut. 50, S2, p. A92-A92, 1 p.

    Research output: Contribution to journal › Meeting abstract

  407. Pyst1/MKP3, a novel dual-specificity phosphatase, and FGF signalling in chick limb development

    Eblaghie, M. C., Sanz-Ezquerro, J. J., Dickinson, R. J., Munsterberg, A., Keyse, S. & Tickle, C. 2002 In : Journal of Anatomy. 201, 5, p. 418

    Research output: Contribution to journal › Article

  408. Relation of mismatch repair protein status with mutational and chromosomal abnormalities in colorectal cancer

    Allen, D., Smith, G., Steele, R. J. C., Wolf, C. R. & Carey, F. A. 2002 In : Journal of Pathology. 198, 1, p. 34A-34A, 1 p.

    Research output: Contribution to journal › Meeting abstract

  409. Relation of mismatch repair protein status with mutational and chromosomal abnormalities in colorectal cancer

    Allen, D., Smith, G., Steele, R. J. C., Wolf, C. R. & Carey, F. A. 2002

    Research output: Contribution to conference › Abstract

  410. S100A4 (p9Ka) protein in colon carcinoma and liver metastases: association with carcinoma cells and T-lymphocytes

    Taylor, S., Herrington, S., Prime, W., Rudland, P. S. & Barraclough, R. 2002 In : British Journal of Cancer. 86, 3, p. 409-416, 8 p.

    Research output: Contribution to journal › Article

  411. The adenoma carcinoma sequence in colorectal cancer - evidence for separate pathways based on p53 and K-ras mutation and chromosomal analysis

    Leslie, A., Smith, G., Kernohan, N. M., Pratt, N., Steele, R. J. C., Wolf, C. R. & Carey, F. A. 2002 In : Journal of Pathology. 198, 1, p. 4A-4A, 1 p.

    Research output: Contribution to journal › Meeting abstract

  412. The adenoma carcinoma sequence in colorectal cancer - evidence for separate pathways based on p53 and K-ras mutation and chromosomal analysis

    Leslie, A., Smith, G., Kernohan, N. M., Pratt, N., Steele, R. J. C., Wolf, C. R. & Carey, F. A. 2002

    Research output: Contribution to conference › Paper

  413. The association of viral infection and chronic allograft nephropathy with graft dysfunction after renal transplantation

    Tong, C. Y. W., Bakran, A., Peiris, J. S. M., Muir, P. & Herrington, C. S. 2002 In : Transplantation. 74, 4, p. 576-578, 3 p.

    Research output: Contribution to journal › Article

  414. The use of in vitro immunisation, as an adjunct to monoclonal antibody production, may result in the production of hybridomas secreting polyreactive antibodies

    McMahon, M. J. & O'Kennedy, R. 1-Dec-2001 In : Journal of immunological methods. 258, 1-2, p. 27-36, 10 p.

    Research output: Contribution to journal › Article

  415. Loss of cytokeratin 14 expression is related to human papillomavirus type and lesion grade in squamous intraepithelial lesions of the cervix

    Southern, S. A., McDicken, I. W. & Herrington, C. S. Dec-2001 In : Human Pathology. 32, 12, p. 1351-1355, 5 p.

    Research output: Contribution to journal › Article

  416. Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation

    Li, J., Gorospe, M., Hutter, D., Barnes, J., Keyse, S. M. & Liu, Y. Dec-2001 In : Molecular and Cellular Biology. 21, 23, p. 8213-24, 12 p.

    Research output: Contribution to journal › Article

  417. Allelic imbalance is not restricted to numerically abnormal chromosomes in epithelial ovarian tumours

    Evans, M. F. & Herrington, C. S. Nov-2001 In : Journal of Pathology. 195, 4, p. 443-450, 8 p.

    Research output: Contribution to journal › Article

  418. Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover

    Dumaz, N., Milne, D. M., Jardine, L. J. & Meek, D. W. 15-Oct-2001 In : Biochemical Journal. 359, 2, p. 459-464, 6 p.

    Research output: Contribution to journal › Article

  419. Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR

    Finnström, N., Bjelfman, C., Söderström, T. G., Smith, G., Egevad, L., Norlén, B. J., Wolf, C. R. & Rane, A. Oct-2001 In : European Journal of Clinical Investigation. 31, 10, p. 880-6, 7 p.

    Research output: Contribution to journal › Article

  420. What we could do now: molecular pathology of gynaecological cancer

    Herrington, C. S. Aug-2001 In : Molecular Pathology. 54, 4, p. 222-224, 3 p.

    Research output: Contribution to journal › Scientific review

  421. Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GST ∏) influences cell proliferation pathways

    Ruscoe, J. E., Rosario, L. A., Wang, T., Gate, L., Arifoglu, P., Wolf, C. R., Henderson, C. J., Ronai, Z. & Tew, K. D. 1-Jul-2001 In : Journal of Pharmacology and Experimental Therapeutics. 298, 1, p. 339-345, 7 p.

    Research output: Contribution to journal › Article

  422. Human papillomavirus in pterygium

    Gallagher, M. J., Giannoudis, A., Herrington, C. S. & Hiscott, P. Jul-2001 In : British Journal of Ophthalmology. 85, 7, p. 782-784, 3 p.

    Research output: Contribution to journal › Article

  423. Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling

    Glading, A., Uberall, F., Keyse, S. M., Lauffenburger, D. A. & Wells, A. 29-Jun-2001 In : Journal of Biological Chemistry. 276, 26, p. 23341-8, 8 p.

    Research output: Contribution to journal › Article

  424. Tetrasomy is induced by human papillomavirus type 18 E7 gene expression in keratinocyte raft cultures

    Southern, S. A., Noya, F., Meyers, C., Broker, T. R., Chow, L. T. & Herrington, C. S. 15-Jun-2001 In : Cancer Research. 61, 12, p. 4858-4863, 6 p.

    Research output: Contribution to journal › Article

  425. Loss of sequences on the short arm of chromosome 17 is a late event in squamous carcinoma of the cervix

    Herrington, C. S., Worsham, M., Southern, S. A., Mackowiak, P. & Wolman, S. R. Jun-2001 In : Molecular Pathology. 54, 3, p. 160-164, 5 p.

    Research output: Contribution to journal › Article

  426. Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence

    Coates, P. J., Nenutil, R., McGregor, A., Picksley, S. M., Crouch, D. H., Hall, P. A. & Wright, E. G. 1-May-2001 In : Experimental Cell Research. 265, 2, p. 262-273, 12 p.

    Research output: Contribution to journal › Article

  427. Variation in the E2-binding domain of HPV 16 is associated with high-grade squamous intraepithelial lesions of the cervix

    Giannoudis, A., van Duin, M., Snijders, P. J. F. & Herrington, C. S. 20-Apr-2001 In : British Journal of Cancer. 84, 8, p. 1058-1063, 6 p.

    Research output: Contribution to journal › Article

  428. Phosphorylation of murine double minute clone 2 (MDM2) protein at serine-267 by protein kinase CK2 in vitro and in cultured cells

    Hjerrild, M., Milne, D., Dumaz, N., Hay, T., Issinger, O-G. & Meek, D. 15-Apr-2001 In : Biochemical Journal. 355, P2, p. 347-56, 10 p.

    Research output: Contribution to journal › Article

  429. Does HPV testing have a role in primary cervical screening?

    Herrington, C. S. Apr-2001 In : Cytopathology : Official Journal of the British Society for Clinical Cytology. 12, 2, p. 71-74, 4 p.

    Research output: Contribution to journal › Editorial

  430. Human papillomavirus variants and squamous neoplasia of the cervix

    Giannoudis, A. & Herrington, C. S. Mar-2001 In : Journal of Pathology. 193, 3, p. 295-302, 8 p.

    Research output: Contribution to journal › Scientific review

  431. An essential role for calmodulin in regulating human T cell aggregation

    Fagerholm, S. C., Prescott, A., Cohen, P., Gahmberg, C. G. & Lehto, V-P. (ed.) 28-Feb-2001 In : FEBS Letters. 491, 1-2, p. 131-6, 6 p.

    Research output: Contribution to journal › Article

  432. Implication of GST-pi expression in colon carcinogenesis

    Niitsu, Y., Takayama, T., Miyanishi, K., Nobuoka, A., Hayashi, T., Nakajima, T., Miyake, S., Henderson, C. J. & Wolf, R. 28-Feb-2001 In : Chemico-Biological Interactions. 133, 1-3, p. 287-290, 4 p.

    Research output: Contribution to journal › Meeting abstract

  433. The Nrf2 transcription factor regulates basal expression of class Alpha and class Mu glutathione S-transferases in the mouse, but not necessarily their induction by cancer chemopreventive agents

    McMaghon, M., Chanas, S. A., Henderson, C. J., Wolf, C. R., Yamamoto, M. & Hayes, J. D. 28-Feb-2001 In : Chemico-Biological Interactions. 133, 1-3, p. 291-294, 4 p.

    Research output: Contribution to journal › Article

  434. Catalytic activity of protein kinase CK1 δ (casein kinase 1δ) is essential for its normal subcellular localization

    Milne, D. M., Looby, P. & Meek, D. W. 1-Feb-2001 In : Experimental Cell Research. 263, 1, p. 43-54, 12 p.

    Research output: Contribution to journal › Article

  435. Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1

    Slack, D. N., Seternes, O-M., Gabrielsen, M. & Keyse, S. M. 30-Jan-2001 In : Journal of Biological Chemistry. 276, 19, p. 16491-500, 10 p.

    Research output: Contribution to journal › Article

  436. Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death

    Inman, G. J., Binné, U. K., Parker, G. A., Farrell, P. J. & Allday, M. J. 2001 In : Journal of Virology. 75, 5, p. 2400-2410, 11 p.

    Research output: Contribution to journal › Article

  437. Alteration of phase II drug detoxifying enzyme levels in Barrett's metaplasia compared to normal oesophageal epithelium

    Cobbe, S. C., Scobie, G. C., Hayes, J. D., Kernohan, N. K. & Dillon, J. F. 2001 In : Gut. 48, S1, p. A29, 1 p.

    Research output: Contribution to journal › Meeting abstract

  438. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease

    Kantachuvesiri, S., Fleming, S., Peters, J., Peters, B., Brooker, G., Lammie, A. G., McGrath, I., Kotelevtsev, Y. & Mullins, J. J. 2001 In : Journal of Biological Chemistry. 276, 39, p. 36727-33, 7 p.

    Research output: Contribution to journal › Article

  439. Differential post-translational modification of the tumour suppressor proteins Rb and p53 modulate the rates of radiation-induced apoptosis in vivo

    Wallace, M., Coates, P. J., Wright, E. G. & Ball, K. L. 2001 In : Oncogene. 20, 28, p. 3597-3608, 12 p.

    Research output: Contribution to journal › Article

  440. Gastrin mediated expression of p53 in AGS Gastric cancer cells

    Cotton, J. P., Oglesby, S. D., Thompson, A. M. & Dillon, J. F. 2001 In : Gut. 48, S1, p. A17, 1 p.

    Research output: Contribution to journal › Meeting abstract

  441. Human papillomavirus and cervical cancer: where are we now?

    Kirwan, J. M. J. & Herrington, C. S. 2001 In : BJOG: An International Journal of Obstetrics & Gynaecology. 108, 12, p. 1204-1213, 10 p.

    Research output: Contribution to journal › Scientific review

  442. Investigation of interaction between N-acetyltransferase 2 (NAT2) phenotype and heterocyclic amines as potential risk factors for colorectal cancer

    Barrett, J. H., Bishop, D. T., Waxman, R., Forman, D., Lightfoot, T., Garner, C., Smith, G. & Wolf, R. 2001 In : American Journal of Human Genetics. 69, 4 Suppl., p. 263-263, 1 p., 469

    Research output: Contribution to journal › Meeting abstract

  443. Investigation of interaction between N-acetyltransferase 2 (NAT2) phenotype and heterocyclic amines as potential risk factors for colorectal cancer

    Barrett, J. H., Bishop, D. T., Waxman, R., Forman, D., Lightfoot, T., Garner, C., Smith, G. & Wolf, R. 2001

    Research output: Contribution to conference › Paper

  444. Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

    Hayes, J. D. & McMahon, M. 2001 In : Cancer Letters. 174, 2, p. 103-13, 11 p.

    Research output: Contribution to journal › Article

  445. The p53 functional yeast assay predicts radiation sensitivity in gastro-oesophageal cell lines

    Oglesby, S. D., Warbrick, E., Johnston, D. A., Dillon, J. F., Munro, A. J., Hupp, T. R. & Thompson, A. M. 2001 In : British Journal of Cancer. 85, S1, p. 37-37, 1 p.

    Research output: Contribution to journal › Meeting abstract

  446. Direct transactivation of c-Ha-Ras gene by p53: evidence for its involvement in p53 transactivation activity and p53-mediated apoptosis

    Deguin-Chambon, V., Vacher, M., Jullien, M., May, E. & Bourdon, J-C. 30-Nov-2000 In : Oncogene. 19, 51, p. 5831-5841, 11 p.

    Research output: Contribution to journal › Article

  447. IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects

    Behrend, L., Milne, D. M., Stöter, M., Deppert, W., Campbell, L. E., Meek, D. W. & Knippschild, U. 9-Nov-2000 In : Oncogene. 19, 47, p. 5303-13, 11 p.

    Research output: Contribution to journal › Article

  448. Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi

    Henderson, C. J., Wolf, C. R., Kitteringham, N., Powell, H., Otto, D. & Park, B. K. 7-Nov-2000 In : Proceedings of the National Academy of Sciences of the United States of America. 97, 23, p. 12741-12745, 5 p.

    Research output: Contribution to journal › Article

  449. Preclinical studies with a glutathione S-transferase P1-1 (GSTP1-1) activated prodrug.

    Rosario, L. A., O'Brien, M. L., Schow, S. R., Henderson, C. J., Wolf, C. R. & Tew, K. D. Nov-2000 In : Clinical Cancer Research. 6, Supplement, p. 4489S-4489S, 1 p., 114

    Research output: Contribution to journal › Meeting abstract

  450. CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin

    Sánchez-Pérez, I., Martínez-Gomariz, M., Williams, D., Keyse, S. M. & Perona, R. 26-Oct-2000 In : Oncogene. 19, 45, p. 5142-52, 11 p.

    Research output: Contribution to journal › Article

  451. Apoptosis induced by TGF-beta 1 in Burkitt's lymphoma cells is caspase 8 dependent but is death receptor independent

    Inman, G. J. & Allday, M. J. 1-Sep-2000 In : Journal of Immunology. 165, 5, p. 2500-10, 11 p.

    Research output: Contribution to journal › Article

  452. HPV-16 E2 gene disruption and sequence variation in CIN 3 lesions and invasive squamous cell carcinomas of the cervix: relation to numerical chromosome abnormalities

    Graham, D. A. & Herrington, C. S. Aug-2000 In : Molecular Pathology. 53, 4, p. 201-206, 6 p.

    Research output: Contribution to journal › Article

  453. Polyreactivity as an acquired artefact, rather than a physiologic property, of antibodies: evidence that monoreactive antibodies may gain the ability to bind to multiple antigens after exposure to low pH

    McMahon, M. J. & O'Kennedy, R. 31-Jul-2000 In : Journal of immunological methods. 241, 1-2, p. 1-10, 10 p.

    Research output: Contribution to journal › Article

  454. Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains

    Hay, T. J. & Meek, D. W. 28-Jul-2000 In : FEBS Letters. 478, 1-2, p. 183-186, 4 p.

    Research output: Contribution to journal › Article

  455. Disruption of cell cycle central by human papillomaviruses with special reference to cervical carcinoma

    Southern, S. A. & Herrington, C. S. Jul-2000 In : International Journal of Gynecological Cancer. 10, 4, p. 263-274, 12 p.

    Research output: Contribution to journal › Scientific review

  456. High-grade squamous intraepithelial neoplasia in a Bartholin's gland cyst associated with HPV 16 infection

    Sheard, J. D. H., Vijayanand, R., Herrington, C. S., Giannoudis, A. & Shaw, G. Jul-2000 In : Histopathology. 37, 1, p. 87-88, 2 p.

    Research output: Contribution to journal › Letter

  457. Synergistic activation of the mkp-1 gene by protein kinase A signaling and USF, but not c-Myc

    Sommer, A., Burkhardt, H., Keyse, S. M. & Lüscher, B. 2-Jun-2000 In : FEBS Letters. 474, 2-3, p. 146-50, 5 p.

    Research output: Contribution to journal › Article

  458. "High risk" HPV types are frequently detected in potentially malignant and malignant oral lesions, but not in normal oral mucosa

    Bouda, M., Gorgoulis, V. G., Kastrinakis, N. G., Giannoudis, A., Tsoli, E., Danassi-Afentaki, D., Foukas, P., Kyroudi, A., Laskaris, G., Herrington, C. S. & Kittas, C. Jun-2000 In : Modern Pathology. 13, 6, p. 644-653, 10 p.

    Research output: Contribution to journal › Article

  459. How to implement dietary changes to prevent the development of metabolic syndrome

    Anderson, A. S. Jun-2000 In : British Journal of Nutrition. 83 , S1, p. S165-S168, 4 p.

    Research output: Contribution to journal › Article

  460. Utilization of human tissue in breast cancer research

    Prime, W., Sobel, M. E. & Herrington, C. S. 13-Apr-2000 In : Breast Cancer Research. 2, 4, p. 237-240, 4 p.

    Research output: Contribution to journal › Scientific review

  461. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling

    Keyse, S. M. 1-Apr-2000 In : Current Opinion in Cell Biology. 12, 2, p. 186-92, 7 p.

    Research output: Contribution to journal › Article

  462. The role of p53 in the response to mitotic spindle damage

    Meek, D. W. Apr-2000 In : Pathologie-Biologie. 48, 3, p. 246-54, 9 p.

    Research output: Contribution to journal › Article

  463. Cytochrome P450s and chemoprevention

    Henderson, C. J., Sahraouei, A. & Wolf, C. R. Feb-2000 In : Biochemical Society Transactions. 28, 2, p. 42-46, 5 p.

    Research output: Contribution to journal › Article

  464. The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

    Hayes, J. D., Chanas, S. A., Henderson, C. J., McMahon, M., Sun, C., Moffat, G. J., Wolf, C. R. & Yamamoto, M. Feb-2000 In : Biochemical Society Transactions. 28, 2, p. 33-41, 9 p.

    Research output: Contribution to journal › Article

  465. Basal keratinocyte tetrasomy in low-grade squamous intra-epithelial lesions of the cervix is restricted to high and intermediate risk HPV infection but is not type-specific

    Giannoudis, A., Evans, M. F., Southern, S. A. & Herrington, C. S. Jan-2000 In : British Journal of Cancer. 82, 2, p. 424-428, 5 p.

    Research output: Contribution to journal › Article

  466. A novel 'two-component' protein containing histidine kinase and response regulator domains required for sporulation in Aspergillus nidulans

    Appleyard, M. V. C. L., McPheat, W. L. & Stark, M. J. R. 2000 In : Current Genetics. 37, 6, p. 364-372, 9 p.

    Research output: Contribution to journal › Article

  467. A recQ family DNA helicase gene from Aspergillus nidulans

    Appleyard, M. V. C. L., McPheat, W. L. & Stark, M. J. R. 2000 In : Mitochondrial DNA. 11, 3-4, p. 315-319, 5 p.

    Research output: Contribution to journal › Article

  468. Analysis of multisite phosphorylation of the p53 tumor-suppressor protein by tryptic phosphopeptide mapping

    Meek, D. W. & Milne, D. M. 2000 In : Methods in Molecular Biology (Clifton, N.J.). 99, p. 447-63, 17 p.

    Research output: Contribution to journal › Article

  469. Characterization of the expression pattern of p63 alpha and delta Np63 alpha in benign and malignant oral epithelial lesions

    Nylander, K., Coates, P. J. & Hall, P. A. 2000 In : International Journal of Cancer. 87, 3, p. 368-372, 5 p.

    Research output: Contribution to journal › Article

  470. Differential expression of p53 and p21 in low grade cervical squamous intraepithelial lesions infected with low, intermediate, and high risk human papillomaviruses

    Giannoudis, A. & Herrington, C. S. 2000 In : Cancer. 89, 6, p. 1300-1307, 8 p.

    Research output: Contribution to journal › Article

  471. Evidence for keratinocyte immortalization in high-grade squamous intraepithelial lesions of the cervix infected with high-risk human papillomaviruses

    Southern, S. A., McDicken, I. W. & Herrington, C. S. 2000 In : Laboratory Investigation. 80, 4, p. 539-544, 6 p.

    Research output: Contribution to journal › Article

  472. Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6

    Ellis, S. W., Hayhurst, G. P., Lightfoot, T., Smith, G., Harlow, J., Rowland-Yeo, K., Larsson, C., Mahling, J., Lim, C. K., Wolf, C. R., Blackburn, M. G., Lennard, M. S. & Tucker, G. T. 2000 In : Biochemical Journal. 345 , 3, p. 565-571, 7 p.

    Research output: Contribution to journal › Article

  473. Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus

    Mullins, L. J., Payne, C. M., Kotelevtseva, N., Brooker, G., Fleming, S., Harris, S. & Mullins, J. J. 2000 In : Journal of Biological Chemistry. 275, 51, p. 40378-84, 7 p.

    Research output: Contribution to journal › Article

  474. Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

    Munsch, D., Watanabe-Fukunaga, R., Bourdon, J-C., Nagata, S., May, E., Yonish-Rouach, E. & Reisdorf, P. 2000 In : Journal of Biological Chemistry. 275, 6, p. 3867-3872, 6 p.

    Research output: Contribution to journal › Article

  475. Malignant hypertension - the role of the paracrine renin-angiotensin system

    Fleming, S. 2000 In : Journal of Pathology. 192, 2, p. 135-9, 5 p.

    Research output: Contribution to journal › Article

  476. Pharmacogenetics

    Wolf, C. R., Smith, G. & Smith, R. L. 2000 In : British Medical Journal. 320, 7240, p. 987-90, 4 p.

    Research output: Contribution to journal › Article

  477. Precancerous lesions in the kidney

    Van Poppel, H., Nilsson, S., Algaba, F., Bergerheim, U., Dal Cin, P., Fleming, S., Hellsten, S., Kirkali, Z., Klotz, L., Lindblad, P., Ljungberg, B., Mulders, P., Roskams, T., Ross, R. K., Walker, C. & Wersäll, P. 2000 In : Scandinavian Journal of Urology and Nephrology. Supplementum. 205, p. 136-65, 30 p.

    Research output: Contribution to journal › Article

  478. Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins

    Nijtmans, L. G. J., de Jong, L., Artal Sanz, M., Coates, P. J., Berden, J. A., Back, J. W., Muijsers, A. O., van der Spek, H. & Grivell, L. A. 2000 In : EMBO Journal. 19, 11, p. 2444-2451, 8 p.

    Research output: Contribution to journal › Article

  479. Protein kinase D :A selective target for antigen receptors and a downstream target for protein kinase C in lymphocytes

    Matthews, S. A., Rozengurt, E. & Cantrell, D. 2000 In : Journal of Experimental Medicine. 191, 12, p. 2075-82, 8 p.

    Research output: Contribution to journal › Article

  480. Resistance to TGF-beta1 correlates with a reduction of TGF-beta type II receptor expression in Burkitt's lymphoma and Epstein-Barr virus-transformed B lymphoblastoid cell lines

    Inman, G. J. & Allday, M. J. 2000 In : Journal of General Virology. 81, 6, p. 1567-78, 12 p.

    Research output: Contribution to journal › Article

  481. Signal transduction by the high-affinity immunoglobulin E receptor Fc epsilon RI: coupling form to function

    Nadler, M. J. S., Matthews, S. A., Turner, H. & Kinet, J-P. 2000 In : Advances in immunology. 76, p. 325-55, 31 p.

    Research output: Contribution to journal › Article

  482. Spatial and temporal regulation of protein kinase D (PKD)

    Matthews, S. A., Iglesias, T., Rozengurt, E. & Cantrell, D. 2000 In : EMBO Journal. 19, 12, p. 2935-45, 11 p.

    Research output: Contribution to journal › Article

  483. Surgical pathology of renal epithelial neoplasms: recent advances and current status

    Fleming, S. & O'Donnell, M. 2000 In : Histopathology. 36, 3, p. 195-202, 8 p.

    Research output: Contribution to journal › Article

  484. Transcriptional activation of tyrosinase and TRP-I by p53 links UV irradiation to the protective tanning response

    Nylander, K., Bourdon, J-C., Bray, S. E., Gibbs, N. K., Kay, R., Hart, I. & Hall, P. A. 2000 In : Journal of Pathology. 190, 1, p. 39-46, 8 p.

    Research output: Contribution to journal › Article

  485. Verrucous carcinoma arising in pseudoepitheliomatous keratotic and micaceous balanitis, without evidence of human papillomavirus

    Child, F. J., Kim, B. K., Ganesan, R., Southern, S. A., Herrington, C. S. & Calonje, E. 2000 In : British Journal of Dermatology. 143, 1, p. 183-187, 5 p.

    Research output: Contribution to journal › Article

  486. Who's responsible for the food shopping? A study of young Scottish couples in their 'honeymoon' period

    Anderson, A. S. & Marshall, D. W. 2000 In : International Review of Retail, Distribution and Consumer Research. 10, 1, p. 59-72

    Research output: Contribution to journal › Article

  487. Protein kinase CK1 is a p53-threonine 18 kinase which requires prior phosphorylation of serine 15

    Dumaz, N., Milne, D. M. & Meek, D. W. 17-Dec-1999 In : FEBS Letters. 463, 3, p. 312-316, 5 p.

    Research output: Contribution to journal › Article

  488. Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2

    Dumaz, N. & Meek, D. W. 15-Dec-1999 In : EMBO Journal. 18, 24, p. 7002-7010, 9 p.

    Research output: Contribution to journal › Article

  489. Mechanisms of switching on p53: a role for covalent modification?

    Meek, D. W. 13-Dec-1999 In : Oncogene. 18, 53, p. 7666-7675, 10 p.

    Research output: Contribution to journal › Article

  490. Phosphorylation of murine p53, but not human p53, by MAP kinase in vitro and in cultured cells highlights species-dependent variation in post-translational modification

    Jardine, L. J., Milne, D. M., Dumaz, N. & Meek, D. W. 9-Dec-1999 In : Oncogene. 18, 52, p. 7602-7607, 6 p.

    Research output: Contribution to journal › Article

  491. Leukocyte adhesion: an integrated molecular process at the leukocyte plasma membrane

    Gahmberg, C. G., Valmu, L., Kotovuori, A., Kotovuori, P., Hilden, T. J., Fagerholm, S., Kantor, C., Nurminen, T., Ihanus, E. & Tian, L. Aug-1999 In : Bioscience Reports. 19, 4, p. 273-281, 9 p.

    Research output: Contribution to journal › Scientific review

  492. The cytoskeletal association of CD11/CD18 leukocyte integrins in phorbol ester-activated cells correlates with CD18 phosphorylation

    Valmu, L., Fagerholm, S., Suila, H. & Gahmberg, C. G. Jul-1999 In : European Journal of Immunology. 29, 7, p. 2107-2118, 12 p.

    Research output: Contribution to journal › Article

  493. Leukocyte adhesion: a fundamental process in leukocyte physiology

    Gahmberg, C. G., Valmu, L., Tian, L., Kotovuori, P., Fagerholm, S., Kotovuori, A., Kantor, C. & Hilden, T. May-1999 In : Brazilian Journal of Medical and Biological Research. 32, 5, p. 511-517, 7 p.

    Research output: Contribution to journal › Article

  494. Regulation of JNK signaling by GSTp

    Adler, V., Yin, Z., Fuchs, S. Y., Benezra, M., Rosario, L., Tew, K. D., Pincus, M. R., Sardana, M., Henderson, C. J., Wolf, C. R., Davis, R. J. & Ronai, Z. 1-Mar-1999 In : EMBO Journal. 18, 5, p. 1321-1334, 14 p.

    Research output: Contribution to journal › Article

  495. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

    Brunet, A., Roux, D., Lenormand, P., Dowd, S., Keyse, S. & Pouysségur, J. 1-Feb-1999 In : EMBO Journal. 18, 3, p. 664-74, 11 p.

    Research output: Contribution to journal › Article

  496. Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

    Stewart, A. E., Dowd, S., Keyse, S. M. & McDonald, N. Q. Feb-1999 In : Nature Structural & Molecular Biology. 6, 2, p. 174-81, 8 p.

    Research output: Contribution to journal › Article

  497. Development of an interview-administered food-frequency questionnaire for use amongst women of South Asian ethnic origin in Britain

    Kassam-Khamis, T., Nanchahal, K., Mangtani, P., dos Santos Silva, I., McMichael, A. & Anderson, A. Feb-1999 In : Journal of Human Nutrition and Dietetics. 12, 1, p. 7-19, 13 p.

    Research output: Contribution to journal › Article

  498. Protein kinase CK2-dependent regulation of p53 function: evidence that the phosphorylation status of the serine 386 (CK2) site of p53 is constitutive and stable

    McKendrick, L., Milne, D. & Meek, D. Jan-1999 In : Molecular and Cellular Biochemistry. 191, 1-2, p. 187-199, 13 p.

    Research output: Contribution to journal › Article

  499. A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome

    Patek, C. E., Little, M. H., Fleming, S., Miles, C., Charlieu, J. P., Clarke, A. R., Miyagawa, K., Christie, S., Doig, J., Harrison, D. J., Porteous, D. J., Brookes, A. J., Hooper, M. L. & Hastie, N. D. 1999 In : Proceedings of the National Academy of Sciences of the United States of America. 96, 6, p. 2931-6, 6 p.

    Research output: Contribution to journal › Article

  500. Adaptive responses to environmental chemicals

    Wolf, C. R., Smith, G., Smith, A. G., Brown, K. & Henderson, C. J. 1999 Cellular responses to stress. Downes, C. P., Wolf, C. R. & Lane, D. P. (eds.). London: Portland Press Ltd, p. 129-139 11 p. (Biochemical Society symposia; 64).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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