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Division of Cancer Research

  1. The psychological impact of a colorectal cancer diagnosis following a negative fecal occult blood test result

    Miles, A., McClements, P. L., Steele, R. J. C., Redeker, C., Sevdalis, N. & Wardle, J. 24 Jul 2015 In : Cancer Epidemiology, Biomarkers & Prevention. 24, 7, p. 1032-1038 7 p.

    Research output: Contribution to journalArticle

  2. Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

    Rog-Zielinska, E. A., Craig, M. A., Manning, J. R., Richardson, R. V., Gowans, G. J., Dunbar, D. R., Gharbi, K., Kenyon, C. J., Holmes, M. C., Hardie, D. G., Smith, G. L. & Chapman, K. E. 1 Jul 2015 In : Cell Death & Differentiation. 22, 7, p. 1106-1116 11 p.

    Research output: Contribution to journalArticle

  3. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., Macleod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & on behalf of the BeWEL team Jul 2015 In : Colorectal Disease. 17, 7, p. 589-594 6 p.

    Research output: Contribution to journalArticle

  4. Loss-of-function mutations in the gene encoding filaggrin are not strongly associated with chronic actinic dermatitis

    Harkins, C. P., Waters, A., Kerr, A., Campbell, L., McLean, W. H. I., Brown, S. J. & Ibbotson, S. H. Jul 2015 In : Journal of Investigative Dermatology. 135, 7, p. 1919-1921 3 p.

    Research output: Contribution to journalLetter

  5. Motion estimation-based image enhancement in ultrasound imaging

    Morin, R., Basarab, A., Bidon, S. & Kouamé, D. Jul 2015 In : Ultrasonics. 60, p. 19-26 8 p.

    Research output: Contribution to journalArticle

  6. Individual variability analysis of fluorescence parameters measured in skin with different levels of nutritive blood flow

    Dunaev, A. V., Dremin, V. V., Zherebtsov, E. A., Rafailov, I. E., Litvinova, K. S., Palmer, S. G., Stewart, N. A., Sokolovski, S. G. & Rafailov, E. U. Jun 2015 In : Medical Engineering & Physics. 37, 6, p. 574-583 10 p.

    Research output: Contribution to journalArticle

  7. Nrf2 activation protects against solar-simulated ultraviolet radiation in mice and humans

    Knatko, E. V., Ibbotson, S. H., Zhang, Y., Higgins, M., Fahey, J. W., Talalay, P., Dawe, R. S., Ferguson, J., Huang, J. T-J., Clarke, R., Zheng, S., Saito, A., Kalra, S., Benedict, A. L., Honda, T., Proby, C. M. & Dinkova-Kostova, A. T. Jun 2015 In : Cancer Prevention Research. 8, 6, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  8. Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma

    Boldrup, L., Coates, P. J., Laurell, G., Wilms, T., Fahraeus, R. & Nylander, K. 26 May 2015 In : British Journal of Cancer. 112, 11, p. 1760-1765 6 p.

    Research output: Contribution to journalArticle

  9. MAGE-A cancer/testis antigens inhibit MDM2 ubiquitylation function and promote increased levels of MDM4

    Marcar, L., Ihrig, B., Hourihan, J., Bray, S. E., Quinlan, P. R., Jordan, L. B., Thompson, A. M., Hupp, T. R. & Meek, D. W. 22 May 2015 In : PLoS ONE. 10, 5, 19 p., e0127713

    Research output: Contribution to journalArticle

  10. Monte Carlo modelling of daylight activated photodynamic therapy

    Campbell, C. L., Wood, K., Valentine, R. M., Brown, C. T. A. & Moseley, H. 21 May 2015 In : Physics in Medicine and Biology. 60, 10, p. 4059-4073 15 p.

    Research output: Contribution to journalArticle

  11. Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

    Wongpaiboonwattana, W. & Stavridis, M. P. 14 May 2015 In : JoVE: Journal of Visualized Experiments. 99, e52823

    Research output: Contribution to journalArticle

  12. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

    Bell, K. F. S., Al-Mubarak, B., Martel, M. A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., Bilican, B., Chowdhry, S., Meakin, P. J., Ashford, M. L. J., Wyllie, D. J. A., Scannevin, R. H., Chandran, S., Hayes, J. D. & Hardingham, G. E. 13 May 2015 In : Nature Communications. 6, 15 p., 7066

    Research output: Contribution to journalArticle

  13. A quantitative assessment of ultraviolet radiation transmission through compression socks

    Valentine, R. & Moseley, H. May 2015 In : British Journal of Dermatology. 172, 5, p. 1445-1447 3 p.

    Research output: Contribution to journalLetter

  14. Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris).

    Moffat, C., Pacheco, J. G., Sharp, S., Samson, A. J., Bollan, K. A., Huang, J., Buckland, S. T. & Connolly, C. N. May 2015 In : FASEB Journal. 29, 5, p. 2112-2119

    Research output: Contribution to journalArticle

  15. Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

    Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

    Research output: Contribution to journalArticle

  16. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

  17. Preliminary validation of thiel embalmed cadavers for laparoscopic radical nephrectomy

    Rai, B. P., Stolzenburg, J. U., Healy, S., Tang, B., Jones, P., Sweeney, C., Somani, B. K., Biyani, C. S. & Nabi, G. May 2015 In : Journal of Endourology. 29, 5, p. 595-603 9 p.

    Research output: Contribution to journalArticle

  18. Quantitative urinary proteomics using stable isotope labelling by peptide dimethylation in patients with prostate cancer

    Li, C., Zang, T., Wrobel, K., Huang, J. T. J. & Nabi, G. May 2015 In : Analytical and Bioanalytical Chemistry. 407, 12, p. 3393-3404 12 p.

    Research output: Contribution to journalArticle

  19. The 1999 Stockholm Consensus Conference on quality specifications in laboratory medicine

    Fraser, C. G. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 837-840 4 p.

    Research output: Contribution to journalArticle

  20. The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site

    Orzol, P., Holcakova, J., Nekulova, M., Nenutil, R., Vojtesek, B. & Coates, P. J. May 2015 In : Histology and Histopathology. 30, 5, p. 503-521 19 p.

    Research output: Contribution to journalArticle

  21. The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

    Woods, J. A., Evans, A., Forbes, P. D., Coates, P. J., Gardner, J., Valentine, R. M., Ibbotson, S. H., Ferguson, J., Fricker, C. & Moseley, H. May 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 3, p. 159-166 8 p.

    Research output: Contribution to journalArticle

  22. MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and-independent mechanisms

    Amankwatia, E. B., Chakravarty, P., Carey, F. A., Weidlich, S., Steele, R. J. C., Munro, A. J., Wolf, C. R. & Smith, G. 28 Apr 2015 In : British Journal of Cancer. 112, 9, p. 1480-1490 11 p.

    Research output: Contribution to journalArticle

  23. Choosing the best method to estimate the energy density of a population using food purchase data

    Wrieden, W. L., Armstrong, J., Anderson, A. S., Sherriff, A. & Barton, K. L. Apr 2015 In : Journal of Human Nutrition and Dietetics. 28, 2, p. 126-134 9 p.

    Research output: Contribution to journalArticle

  24. Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

    Henderson, C. J., McLaughlin, L. A., Scheer, N., Stanley, L. A. & Wolf, C. R. Apr 2015 In : Molecular Pharmacology. 87, 4, p. 733-739 7 p.

    Research output: Contribution to journalArticle

  25. Nrf2 regulates ROS production by mitochondria and NADPH oxidase

    Kovac, S., Angelova, P. R., Holmström, K. M., Zhang, Y., Dinkova-Kostova, A. T. & Abramov, A. Y. Apr 2015 In : Biochimica et Biophysica Acta: General Subjects. 1850, 4, p. 794-801 8 p.

    Research output: Contribution to journalArticle

  26. Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks

    McDermott, F. D., Heeney, A., Kelly, M. E., Steele, R. J., Carlson, G. L. & Winter, D. C. Apr 2015 In : British Journal of Surgery. 102, 5, p. 462-479 18 p.

    Research output: Contribution to journalArticle

  27. Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

    Fleming, S. & 44 others Kovac, M., Navas, C., Horswell, S., Salm, M., Bardella, C., Rowan, A., Stares, M., Castro-Giner, F., Fisher, R., de Bruin, E. C., Kovacova, M., Gorman, M., Makino, S., Williams, J., Jaeger, E., Jones, A., Howarth, K., Larkin, J., Pickering, L., Gore, M., Nicol, D. L., Hazell, S., Stamp, G., O'Brien, T., Challacombe, B., Matthews, N., Phillimore, B., Begum, S., Rabinowitz, A., Varela, I., Chandra, A., Horsfield, C., Polson, A., Tran, M., Bhatt, R., Terracciano, L., Eppenberger-Castori, S., Protheroe, A., Maher, E., El Bahrawy, M., Ratcliffe, P., Heinimann, K., Swanton, C. & Tomlinson, I. 19 Mar 2015 In : Nature Communications. 6, 11 p., 6336

    Research output: Contribution to journalArticle

  28. Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins

    Colin, D. J., Hain, K. O., Allan, L. A. & Clarke, P. R. 11 Mar 2015 In : Open Biology. 5, 13 p., 140156

    Research output: Contribution to journalArticle

  29. Detection of urinary bladder cancer cells using redox ratio and double excitation wavelengths autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 1 Mar 2015 In : Biomedical Optics Express. 6, 3, p. 977-986 10 p.

    Research output: Contribution to journalArticle

  30. An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes

    MacLeod, A. K., Fallon, P. G., Sharp, S., Henderson, C. J., Wolf, C. R. & Huang, J. T-J. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 750-760 11 p.

    Research output: Contribution to journalArticle

  31. Biological variation: a still evolving facet of laboratory medicine

    Simundic, A. M., Bartlett, W. A. & Fraser, C. G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 189-190 2 p.

    Research output: Contribution to journalEditorial

  32. Calculation of limits for significant unidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Mar 2015 In : Annals of Clinical Biochemistry. 52, 2, p. 237-244 8 p.

    Research output: Contribution to journalArticle

  33. Distal nephron neoplasms

    Fleming, S. Mar 2015 In : Seminars in Diagnostic Pathology. 32, 2, p. 114-123 10 p.

    Research output: Contribution to journalArticle

  34. Laser-induced autofluorescence spectroscopy: Can it be of importance in detection of bladder lesions?

    Aboumarzouk, O., Valentine, R., Buist, R., Ahmad, S., Nabi, G., Eljamel, S., Moseley, H. & Kata, S. G. Mar 2015 In : Photodiagnosis and Photodynamic Therapy. 12, 1, p. 76-83 8 p.

    Research output: Contribution to journalArticle

  35. Thiel Embalming Method for Cadaver Preservation: A Review of New Training Model for Urologic Skills Training

    Healy, S. E., Rai, B. P., Biyani, C. S., Eisma, R., Soames, R. W. & Nabi, G. Mar 2015 In : Urology. 85, 3, p. 499-504 6 p.

    Research output: Contribution to journalArticle

  36. Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability

    Henderson, C. J., McLaughlin, L. A., Osuna-Cabello, M., Taylor, M., Gilbert, I., McLaren, A. W. & Wolf, C. R. 1 Feb 2015 In : Biochemical Journal. 465, 3, p. 479-488 10 p.

    Research output: Contribution to journalArticle

  37. Detection and characterisation of biopsy tissue using quantitative optical coherence elastography (OCE) in men with suspected prostate cancer

    Li, C., Guan, G., Ling, Y., Hsu, Y-T., Song, S., Huang, J. T-J., Lang, S., Wang, R. K., Huang, Z. & Nabi, G. 1 Feb 2015 In : Cancer Letters. 357, 1, p. 121-128 8 p.

    Research output: Contribution to journalArticle

  38. Insight from the air-skin interface

    O'Shaughnessy, R. F. L. & Brown, S. J. Feb 2015 In : Journal of Investigative Dermatology. 135, 2, p. 331-333 3 p.

    Research output: Contribution to journalComment/debate

  39. Oxidation reduction is a key process for successful treatment of psoriasis by narrow-band UVB phototherapy

    Gu, X., Nylander, E., Coates, P. J. & Nylander, K. Feb 2015 In : Acta Dermato-Venereologica. 95, 2, p. 140-146 7 p.

    Research output: Contribution to journalArticle

  40. Terms and symbols used in studies on biological variation: the need for harmonization

    Simundic, A. M., Kackov, S., Miler, M., Fraser, C. G. & Petersen, P. H. Feb 2015 In : Clinical Chemistry. 61, 2, p. 438-439 2 p.

    Research output: Contribution to journalLetter

  41. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration

    Pajaud, J., Ribault, C., Ben Mosbah, I., Rauch, C., Henderson, C., Bellaud, P., Aninat, C., Loyer, P., Morel, F. & Corlu, A. 15 Jan 2015 In : Cell Death and Disease. 6, 13 p., e1598

    Research output: Contribution to journalArticle

  42. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

    Brown, S. J. & 38 others Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I., Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S. & Cordell, H. J. 8 Jan 2015 In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticle

  43. An updated Asia Pacific Consensus Recommendations on colorectal cancer screening

    Sung, J. J. Y., Ng, S. C., Chan, F. K. L., Chiu, H. M., Kim, H. S., Matsuda, T., Ng, S. S. M., Lau, J. Y. W., Zheng, S., Adler, S., Reddy, N., Yeoh, K. G., Tsoi, K. K. F., Ching, J. Y. L., Kuipers, E. J., Rabeneck, L., Young, G. P., Steele, R. J., Lieberman, D. & Goh, K. L. Jan 2015 In : Gut. 64, 1, p. 121-132 12 p.

    Research output: Contribution to journalArticle

  44. Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

    Brough, H. A., Liu, A. H., Sicherer, S., Makinson, K., Douiri, A., Brown, S. J., Stephens, A. C., McLean, W. H. I., Turcanu, V., Wood, R. A., Jones, S. M., Burks, W., Dawson, P., Stablein, D., Sampson, H. & Lack, G. Jan 2015 In : Journal of Allergy and Clinical Immunology. 135, 1, p. 164-170.e4 11 p.

    Research output: Contribution to journalArticle

  45. Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection

    Dayalan Naidu, S., Kostov, R. V. & Dinkova-Kostova, A. T. Jan 2015 In : Trends in Pharmacological Sciences. 36, 1, p. 6-14 9 p.

    Research output: Contribution to journalArticle

  46. Viruses and disease: emerging concepts for prevention, diagnosis and treatment

    Herrington, C. S., Coates, P. J. & Duprex, W. P. Jan 2015 In : Journal of Pathology. 235, 2, p. 149-152 4 p.

    Research output: Contribution to journalArticle

  47. A novel excitation-emission wavelength model to facilitate the diagnosis of urinary bladder diseases

    Rafailov, I., Palmer, S., Litvinova, K., Dremin, V., Dunaev, A. & Nabi, G. 2015 Photonic Therapeutics and Diagnostics XI. Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Nuttal, A., Richter, C-P., Skala, M. C., Dewhirst, M. W., Tearney, G. J., Gregory, K. W., Marcu, L., Mandelis, A. & Morris, M. D. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93030W. (Proceedings of SPIE; vol. 9303)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  48. Discrimination of healthy and cancer cells of the bladder by metabolic state, based on autofluorescence

    Palmer, S., Litvinova, K., Rafailov, E. U. & Nabi, G. 2015 Photonic Therapeutics and Diagnostics XI. Choi, B., Kollias, N., Zeng, H., Kang, H. W., Wong, B. J. F., Ilgner, J. F., Nuttal, A., Richter, C-P., Skala, M. C., Dewhirst, M. W., Tearney, G. J., Gregory, K. W., Marcu, L. & Mandelis, A. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93030T. (Proceedings of SPIE; vol. 9303)(Progress In Biomedical Optics And Imaging; vol. 16, no. 1)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  49. Kidney biopsy findings in primary Sjogren syndrome

    Kidder, D., Rutherford, E., Kipgen, D., Fleming, S., Geddes, C. & Stewart, G. A. 2015 In : Nephrology Dialysis Transplantation. 7 p.

    Research output: Contribution to journalArticle

  50. Mitotic kinases and phosphatases cooperate to shape the right response

    Vallardi, G. & Saurin, A. T. 2015 In : Cell Cycle. 14, 6, p. 795-796 2 p.

    Research output: Contribution to journalEditorial

  51. Optical coherence elastography (OCE) as a method for identifying benign and malignant prostate biopsies

    Li, C., Guan, G., Ling, Y., Lang, S., Wang, R. K., Huang, Z. & Nabi, G. 2015 Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIX. Fujimoto, J. G., Izatt, J. A. & Tuchin, V. V. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 93122S. (Proceedings of SPIE; vol. 9312)(Progress in Biomedical Optics and Imaging; vol. 16, no. 10)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  52. Trends in socio-economic inequalities in the Scottish diet: 2001-2009

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. 2015 In : Public Health Nutrition. 12 p.

    Research output: Contribution to journalArticle

  53. Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression

    Rushworth, L. K., Kidger, A. M., Delavaine, L., Stewart, G., van Schelven, S., Davidson, J., Bryant, C. J., Caddye, E., East, P., Caunt, C. J. & Keyse, S. M. 23 Dec 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. 18267-18272 6 p.

    Research output: Contribution to journalArticle

  54. Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells

    Schoenherr, C., Serrels, B., Proby, C., Cunningham, D. L., Findlay, J. E., Baillie, G. S., Heath, J. K. & Frame, M. C. 15 Dec 2014 In : Journal of Cell Science. 127, 24, p. 5303-5316 14 p.

    Research output: Contribution to journalArticle

  55. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

    Mudie, S., Bandarra, D., Batie, M., Biddlestone, J., Moniz, S., Ortmann, B., Shmakova, A. & Rocha, S. 15 Dec 2014 In : Cell Cycle. 13, 24, p. 3878-3891 14 p.

    Research output: Contribution to journalArticle

  56. Quantitative elasticity measurement of urinary bladder wall using laser-induced surface acoustic waves

    Li, C., Guan, G., Zhang, F., Song, S., Wang, R. K., Huang, Z. & Nabi, G. 1 Dec 2014 In : Biomedical Optics Express. 5, 12, p. 4313-4328 16 p.

    Research output: Contribution to journalArticle

  57. Integrated signaling pathway and gene expression regulatory model to dissect dynamics of Escherichia coli challenged mammary epithelial cells

    den Breems, N. Y., Nguyen, L. K. & Kulasiri, D. Dec 2014 In : BioSystems. 126, p. 27-40 14 p.

    Research output: Contribution to journalArticle

  58. Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

    Nijenhuis, W., Vallardi, G., Teixeira, A., Kops, G. J. P. L. & Saurin, A. T. Dec 2014 In : Nature Cell Biology. 16, 12, p. 1257-1264 8 p.

    Research output: Contribution to journalLetter

  59. Photodynamic diagnostic ureterorenoscopy with orally administered 5-aminolaevulinic acid as photosensitiser: how I do it

    Kata, S. G., Nabi, G., Eljamel, S., Chlosta, P., Moseley, H. & Aboumarzouk, O. M. Dec 2014 In : Urologia Internationalis. 93, 4, p. 384-388 5 p.

    Research output: Contribution to journalArticle

  60. Shear-wave elastography contributes to accurate tumour size estimation when assessing small breast cancers

    Mullen, R., Thompson, J. M., Moussa, O., Vinnicombe, S. & Evans, A. Dec 2014 In : Clinical Radiology. 69, 12, p. 1259-1263 5 p.

    Research output: Contribution to journalArticle

  61. Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients

    Fleming, S. & 37 others Gill, A. J., Hes, O., Papathomas, T., Sedivcová, M., Tan, P. H., Agaimy, A., Andresen, P. A., Kedziora, A., Clarkson, A., Toon, C. W., Sioson, L., Watson, N., Chou, A., Paik, J., Clifton-Bligh, R. J., Robinson, B. G., Benn, D. E., Hills, K., Maclean, F., Niemeijer, N. D., Vlatkovic, L., Hartmann, A., Corssmit, E. P. M., van Leenders, G. J. L. H., Przybycin, C., McKenney, J. K., Magi-Galluzzi, C., Yilmaz, A., Yu, D., Nicoll, K. D., Yong, J. L., Sibony, M., Yakirevich, E., Chow, C. W., Miettinen, M., Michal, M. & Trpkov, K. Dec 2014 In : American Journal of Surgical Pathology. 38, 12, p. 1588-1602 15 p.

    Research output: Contribution to journalArticle

  62. Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel cyanoenone and enone benzenesulfonamides

    Ghorab, M. M., Higgins, M., Alsaid, M. S., Arafa, R. K., Shahat, A. A. & Dinkova-Kostova, A. T. Dec 2014 In : Journal of Enzyme Inhibition and Medicinal Chemistry. 29, 6, p. 840-845 6 p.

    Research output: Contribution to journalArticle

  63. HDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agents

    McMahon, M., Campbell, K. H., MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 26 Nov 2014 In : PLoS ONE. 9, 11, e114055

    Research output: Contribution to journalArticle

  64. Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma

    Drew, J. E., Farquharson, A. J., Mayer, C. D., Vase, H. F., Coates, P. J., Steele, R. J. & Carey, F. A. 25 Nov 2014 In : PLoS ONE. 9, 11, 20 p., e113071

    Research output: Contribution to journalArticle

  65. 5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release

    Hothersall, J. D., Alexander, A., Samson, A. J., Moffat, C., Bollan, K. A. & Connolly, C. N. 14 Nov 2014 In : Journal of Biological Chemistry. 289, 46, p. 32020-32029 10 p.

    Research output: Contribution to journalArticle

  66. Malignancy within a tail gut cyst: a case of retrorectal carcinoid tumour

    Abukar, A. A., Parcell, B. J., Lim, C. B., Patil, P. V., Ramsanahie, A., Carey, F., Steele, R. J. C. & Thaha, M. A. 13 Nov 2014 In : Case Reports in Surgery. 2014, 4 p., 454502

    Research output: Contribution to journalArticle

  67. Monitoring Keap1-Nrf2 interactions in single live cells

    Baird, L., Swift, S., Llères, D. & Dinkova-Kostova, A. T. 1 Nov 2014 In : Biotechnology Advances. 32, 6, p. 1133-1144 12 p.

    Research output: Contribution to journalArticle

  68. Impact of faecal occult blood test screening on emergency admissions and short-term outcomes for colorectal cancer

    Libby, G., Brewster, D. H. & Steele, R. J. C. Nov 2014 In : British Journal of Surgery. 101, 12, p. 1607-1615 9 p.

    Research output: Contribution to journalArticle

  69. Laparoscopic nephrectomy for Adult Polycystic Kidney Disease (APKD): safety, feasibility and early outcomes

    Williamson, A., Paterson, S., Erolin, C., Sweeney, C., Townell, N. & Nabi, G. Nov 2014 In : Journal of Endourology. 28, 11, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  70. Risk of AKI with gentamicin as surgical prophylaxis

    Bell, S., Davey, P., Nathwani, D., Marwick, C., Vadiveloo, T., Sneddon, J., Patton, A., Bennie, M., Fleming, S. & Donnan, P. T. Nov 2014 In : Journal of the American Society of Nephrology. 25, 11, p. 2625-2632 8 p.

    Research output: Contribution to journalArticle

  71. Nonredundant Raman imaging using optical eigenmodes

    Kosmeier, S., Zolotovskaya, S., De Luca, A. C., Riches, A., Herrington, C. S., Dholakia, K. & Mazilu, M. 20 Oct 2014 In : Optica. 1, 4, p. 257-263 7 p.

    Research output: Contribution to journalArticle

  72. Fertility preservation in men with cancer

    Tournaye, H., Dohle, G. R. & Barratt, C. L. R. 4 Oct 2014 In : Lancet. 384, 9950, p. 1295-1301 7 p.

    Research output: Contribution to journalArticle

  73. Robotic or open radical cystectomy, which is safer? a systematic review and meta-analysis of comparative studies

    Ishii, H., Rai, B. P., Stolzenburg, J-U., Bose, P., Chlosta, P. L., Somani, B. K., Nabi, G., Qazi, H. A. R., Rajbabu, K., Kynaston, H. & Aboumarzouk, O. M. 2 Oct 2014 In : Journal of Endourology. 28, 10, p. 1215-1223 9 p.

    Research output: Contribution to journalArticle

  74. NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

    South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M. Oct 2014 In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638

    Research output: Contribution to journalArticle

  75. Colorectal cancer screening

    Steele, R. J. C. Oct 2014 In : British Journal of Surgery. 101, 11, p. 1338-1340 3 p.

    Research output: Contribution to journalArticle

  76. Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

    Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P. Oct 2014 In : Stem Cells. 32, 10, p. 2605-2615

    Research output: Contribution to journalArticle

  77. Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

    Simpson, E. L., Chalmers, J. R., Hanifin, J. M., Thomas, K. S., Cork, M. J., McLean, W. H. I., Brown, S. J., Chen, Z., Chen, Y. & Williams, H. C. Oct 2014 In : Journal of Allergy and Clinical Immunology. 134, 4, p. 818-823 6 p.

    Research output: Contribution to journalArticle

  78. Follow-up in early breast cancer - a surgical and radiological perceptive

    Dunn, J. A., Donnelly, P. K., Marshall, A., Wilcox, M., Watson, E., Young, A., Balmer, C., Ramirez, M., Hartup, S., Maxwell, A. J., Evans, A. J. & on behalf of the Mammo-50 trial management group Oct 2014 In : Clinical Oncology. 26, 10, p. 625-629 5 p.

    Research output: Contribution to journalEditorial

  79. Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

    Brough, H. A., Simpson, A., Makinson, K., Hankinson, J., Brown, S., Douiri, A., Belgrave, D. C. M., Penagos, M., Stephens, A. C., McLean, W. H. I., Turcanu, V., Nicolaou, N., Custovic, A. & Lack, G. Oct 2014 In : Journal of Allergy and Clinical Immunology. 134, 4, p. 867-875.e1 10 p.

    Research output: Contribution to journalArticle

  80. Phenotype standardisation of angioedema in the head and neck region caused by agents acting on the angiotensin system

    Wadelius, M., Marshall, S. E., Islander, G., Nordang, L., Karawajczyk, M., Yue, Q-Y., Terreehorst, I., Baranova, E. V., Hugosson, S., Sköldefors, K., Pirmohamed, M., Maitland van der Zee, A-H., Alfirevic, A., Hallberg, P. & Palmer, C. N. A. Oct 2014 In : Clinical Pharmacology & Therapeutics. 96, 4, p. 477-481

    Research output: Contribution to journalScientific review

  81. Sugars and health - risk assessment to risk management

    Anderson, A. S. Oct 2014 In : Public Health Nutrition. 17, 10, p. 2148-2150 3 p.

    Research output: Contribution to journalComment/debate

  82. Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes

    Tsujita, T., Peirce, V., Baird, L., Matsuyama, Y., Takaku, M., Walsh, S. V., Griffin, J. L., Uruno, A., Yamamoto, M. & Hayes, J. D. Oct 2014 In : Molecular and Cellular Biology. 34, 20, p. 3800-3816 17 p.

    Research output: Contribution to journalArticle

  83. Risk determination and prevention of breast cancer

    Howell, A., Anderson, A. S., Clarke, R. B., Duffy, S. W., Evans, D. G., Garcia-Closas, M., Gescher, A. J., Key, T. J., Saxton, J. M. & Harvie, M. N. 28 Sep 2014 In : Breast Cancer Research. 16, 5, 19 p., 446

    Research output: Contribution to journalArticle

  84. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol

    Holt, A-M., Jancey, J., Lee, A. H., Kerr, D. A., Hills, A. P., Anderson, A. S. & Howat, P. A. 25 Sep 2014 In : BMJ Open. 4, 9, 8 p., e005107

    Research output: Contribution to journalArticle

  85. Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery

    El-Mokadem, I., Fitzpatrick, J., Bondad, J., Rauchhaus, P., Cunningham, J., Pratt, N., Fleming, S. & Nabi, G. 23 Sep 2014 In : British Journal of Cancer. 111, 7, p. 1381-1390 10 p.

    Research output: Contribution to journalArticle

  86. Dietary outcomes of a community based intervention for mothers of young children: a randomised controlled trial

    Jancey, J. M., Dos Remedios Monteiro, S. M., Dhaliwal, S. S., Howat, P. A., Burns, S., Hills, A. P. & Anderson, A. S. 23 Sep 2014 In : International Journal of Behavioral Nutrition and Physical Activity. 11, 1, 9 p., 120

    Research output: Contribution to journalArticle

  87. Digital mammographic density and breast cancer risk: a case-control study of six alternative density assessment methods

    Eng, A., Gallant, Z., Shepherd, J., McCormack, V., Li, J., Dowsett, M., Vinnicombe, S., Allen, S. & dos-Santos-Silva, I. 20 Sep 2014 In : Breast Cancer Research. 16, 5, 12 p., 439

    Research output: Contribution to journalArticle

  88. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.

    Sparks, A., Dayal, S., Das, J., Robertson, P., Menendez, S. & Saville, M. K. 18 Sep 2014 In : Oncogene. 33, 38, p. 4685-4696 12 p.

    Research output: Contribution to journalArticle

  89. Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines

    Sawers, L., Ferguson, M. J., Ihrig, B. R., Young, H. C., Chakravarty, P., Wolf, C. R. & Smith, G. 9 Sep 2014 In : British Journal of Cancer. 111, 6, p. 1150-1158

    Research output: Contribution to journalArticle

  90. Mutations in GRHL2 result in an autosomal-recessive ectodermal dysplasia syndrome

    Petrof, G., Nanda, A., Howden, J., Takeichi, T., McMillan, J. R., Aristodemou, S., Ozoemena, L., Liu, L., South, A. P., Pourreyron, C., Dafou, D., Proudfoot, L. E., Al-Ajmi, H., Akiyama, M., McLean, W. H. I., Simpson, M. A., Parsons, M. & McGrath, J. A. 4 Sep 2014 In : American Journal of Human Genetics. 95, 3, p. 308-314 7 p.

    Research output: Contribution to journalArticle

  91. Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase

    Müllers, E., Cascales, H. S., Jaiswal, H., Saurin, A. T. & Lindqvist, A. 1 Sep 2014 In : Cell Cycle. 13, 17, p. 2733-2743 11 p.

    Research output: Contribution to journalArticle

  92. Genes involved in epithelial differentiation and development are differentially expressed in oral and genital lichen planus epithelium compared to normal epithelium

    Danielsson, K., Coates, P. J., Ebrahimi, M., Nylander, E., Wahlin, Y-B. & Nylander, K. Sep 2014 In : Acta Dermato-Venereologica. 94, 5, p. 526-530 5 p.

    Research output: Contribution to journalArticle

  93. Importance of β-defensins in sperm function

    Dorin, J. R. & Barratt, C. L. R. Sep 2014 In : Molecular Human Reproduction. 20, 9, p. 821-826 6 p.

    Research output: Contribution to journalArticle

  94. Leporid immunoglobulin G shows evidence of strong selective pressure on the hinge and CH3 domains

    Pinheiro, A., Woof, J. M., Almeida, T., Abrantes, J., Alves, P. C., Gortázar, C. & Esteves, P. J. Sep 2014 In : Open Biology. 4, 9, 9 p., 140088

    Research output: Contribution to journalArticle

  95. Malignancy-associated hyperamylasaemia

    Srivastava, R., Murphy, M. J. & Fraser, C. G. Sep 2014 In : Annals of Clinical Biochemistry. 51, 5, p. 619 1 p.

    Research output: Contribution to journalLetter

  96. Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

    Marcel, V., Fernandes, K., Terrier, O., Lane, D. P. & Bourdon, J-C. Sep 2014 In : Cell Death & Differentiation. 21, p. 1377-1387 11 p.

    Research output: Contribution to journalArticle

  97. Progress in skin cancer: the U.K. experience

    Leigh, I. M. Sep 2014 In : British Journal of Dermatology. 171, 3, p. 443-445 3 p.

    Research output: Contribution to journalEditorial

  98. The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

    Salmond, R. J., Brownlie, R. J., Morrison, V. L. & Zamoyska, R. Sep 2014 In : Nature Immunology. 15, 9, p. 875-883 8 p.

    Research output: Contribution to journalArticle

  99. Epigenetics in diagnosis, prognostic assessment and treatment of cancer: An update

    Hatzimichael, E., Lagos, K., Sim, V. R., Briasoulis, E. & Crook, T. 26 Aug 2014 In : EXCLI Journal. 13, p. 954-976 23 p.

    Research output: Contribution to journalArticle

  100. BRCA1 is a histone-H2A-specific ubiquitin ligase

    Kalb, R., Mallery, D. L., Larkin, C., Huang, J. T. J. & Hiom, K. 21 Aug 2014 In : Cell Reports. 8, 4, p. 999-1005 7 p.

    Research output: Contribution to journalArticle

  101. Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation

    Hamilton, D. L., Philp, A., MacKenzie, M. G., Patton, A., Towler, M. C., Gallagher, I. J., Bodine, S. C. & Baar, K. 15 Aug 2014 In : American Journal of Physiology, Endocrinology and Metabolism. 307, 4, p. E365-E373 9 p.

    Research output: Contribution to journalArticle

  102. Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR

    Braeuning, A., Gavrilov, A., Brown, S., Wolf, C. R., Henderson, C. J. & Schwarz, M. 1 Aug 2014 In : Toxicological Sciences. 140, 2, p. 259-70 12 p.

    Research output: Contribution to journalArticle

  103. Accuracy of non-operative identification of the sentinel lymph node using combined gamma and ultrasound scanning

    Whelehan, P., Vinnicombe, S. J., Brown, D. C., McLean, D. & Evans, A. Aug 2014 In : Clinical Radiology. 69, 8, p. 849-852 4 p.

    Research output: Contribution to journalArticle

  104. An investigation into the MMP1 gene promoter region polymorphism - 1607 2G with recessive dystrophic epidermolysis bullosa disease severity in northeastern Mexican patients

    Garza-Gómez, J., Cerda-Flores, R. M., Gómez-Flores, M., Salas-Alanís, J. C., Ocampo-Candiani, J., Martínez-Garza, L. E., South, A. P. & Gallardo-Blanco, H. L. Aug 2014 In : International Journal of Dermatology. 53, 8, p. 985-990 6 p.

    Research output: Contribution to journalArticle

  105. Chemical tuning enhances both potency toward Nrf2 and in vitro therapeutic index of triterpenoids

    Copple, I. M., Shelton, L. M., Walsh, J., Kratschmar, D. V., Lister, A., Odermatt, A., Goldring, C. E., Dinkova-Kostova, A. T., Honda, T. & Park, B. K. Aug 2014 In : Toxicological Sciences. 140, 2, p. 462-469 8 p.

    Research output: Contribution to journalArticle

  106. Evidence for aldosterone-dependent growth of renal cell carcinoma

    King, S., Bray, S., Galbraith, S., Christie, L. & Fleming, S. Aug 2014 In : International Journal of Experimental Pathology. 95, 4, p. 244-250 7 p.

    Research output: Contribution to journalArticle

  107. Faecal haemoglobin concentrations vary with sex and age, but data are not transferable across geography for colorectal cancer screening

    Fraser, C. G., Rubeca, T., Rapi, S., Chen, L-S. & Chen, H-H. Aug 2014 In : Clinical Chemistry and Laboratory Medicine. 52, 8, p. 1211-6 6 p.

    Research output: Contribution to journalArticle

  108. Synthesis of 13C215N2-labeled anti-inflammatory and cytoprotective tricyclic bis(cyanoenone) ([13C215N2]-TBE-31) as an internal standard for quantification by stable isotope dilution LC-MS method

    Zheng, S., Huang, J. T. -J., Knatko, E. V., Sharp, S., Higgins, M., Ojima, I., Dinkova-Kostova, A. T. & Honda, T. Aug 2014 In : Journal of Labelled Compounds & Radiopharmaceuticals. 57, 10, p. 606-610 5 p.

    Research output: Contribution to journalArticle

  109. The SNAP trial: a randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - clinical effectiveness and safety until 2 years after delivery, with economic evaluation

    Cooper, S., Lewis, S., Thornton, J. G., Marlow, N., Watts, K., Britton, J., Grainge, M. J., Taggar, J., Essex, H., Parrott, S., Dickinson, A., Whitemore, R., Coleman, T. & Smoking, Nicotine and Pregnancy (SNAP) Trial Team Aug 2014 In : Health Technology Assessment. 18, 54, p. 1-128 128 p.

    Research output: Contribution to journalArticle

  110. Therapeutic targeting of integrin αvβ6 in breast cancer

    Moore, K. M. , Thomas, G. J. , Duffy, S. W. , Warwick, J. , Gabe, R. , Chou, P. , Ellis, I. O. , Green, A. R. , Haider, S. , Brouilette, K. , Saha, A. , Vallath, S. , Bowen, R. , Chelala, C. , Eccles, D. , Tapper, W. J. , Thompson, A. M. , Quinlan, P. , Jordan, L. , Gillett, C. & 8 others Brentnall, A., Violette, S., Weinreb, P. H., Kendrew, J., Barry, S. T., Hart, I. R., Jones, J. L. & Marshall, J. F. Aug 2014 In : Journal of the National Cancer Institute. 106, 8, 14 p., dju169

    Research output: Contribution to journalArticle

  111. Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa

    Cogan, J., Weinstein, J., Wang, X., Hou, Y., Martin, S., South, A. P., Woodley, D. T. & Chen, M. 23 Jul 2014 In : Molecular Therapy.

    Research output: Contribution to journalArticle

  112. Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II

    Magnani, F., Pappas, C. G., Crook, T., Magafa, V., Cordopatis, P., Ishiguro, S., Ohta, N., Selent, J., Bosnyak, S., Jones, E. S., Gerothanassis, I. P., Tamura, M., Widdop, R. E. & Tzakos, A. G. 18 Jul 2014 In : ACS Chemical Biology. 9, 7, p. 1420-1425 6 p.

    Research output: Contribution to journalArticle

  113. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  114. Energy density of the Scottish diet estimated from food purchase data: relationship with socio-economic position and dietary targets

    Barton, K. L., Wrieden, W. L., Sherriff, A., Armstrong, J. & Anderson, A. S. 14 Jul 2014 In : British Journal of Nutrition. 112, 1, p. 80-88 9 p.

    Research output: Contribution to journalArticle

  115. Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast

    Thomas, J., Hanby, A., Pinder, S. E., Ball, G., Lawrence, G., Maxwell, A., Wallis, M., Evans, A., Dobson, H., Clements, K., Thompson, A. & Sloane Project Steering Group Jul 2014 In : European Journal of Cancer. 50, 11, p. 1880-1890 11 p.

    Research output: Contribution to journalArticle

  116. Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

    Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J. Jul 2014 In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

    Research output: Contribution to journalArticle

  117. Mutant p53 accumulation in human breast cancer is not an intrinsic property or dependent on structural or functional disruption but is regulated by exogenous stress and receptor status

    Bouchalova, P., Nenutil, R., Muller, P., Hrstka, R., Appleyard, M. V., Murray, K., Jordan, L. B., Purdie, C. A., Quinlan, P., Thompson, A. M., Vojtesek, B. & Coates, P. J. Jul 2014 In : Journal of Pathology. 233, 3, p. 238-246 9 p.

    Research output: Contribution to journalArticle

  118. A data standard for sourcing fit-for-purpose biological samples in an integrated virtual network of biobanks

    Confederation of Cancer Biobanks (CCB) Working Group 3 Jun 2014 In : Biopreservation and Biobanking. 12, 3, p. 184-191 8 p.

    Research output: Contribution to journalArticle

  119. Comparative cancer survival in European countries

    Munro, A. J. Jun 2014 In : British Medical Bulletin. 110, 1, p. 5-22 18 p.

    Research output: Contribution to journalArticle

  120. Deprivation and faecal haemoglobin: implications for bowel cancer screening

    Digby, J., McDonald, P. J., Strachan, J. A., Libby, G., Steele, R. J. C. & Fraser, C. G. Jun 2014 In : Journal of Medical Screening. 21, 2, p. 95-97 3 p.

    Research output: Contribution to journalArticle

  121. Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization: a solution for practical application

    Li, C., Guan, G., Zhang, F., Nabi, G., Wang, R. K. & Huang, Z. 1 May 2014 In : Biomedical Optics Express. 5, 5, p. 1403-1418 16 p.

    Research output: Contribution to journalArticle

  122. The RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancers

    Iyer, R. S., Nicol, S. M., Quinlan, P. R., Thompson, A. M., Meek, D. W. & Fuller-Pace, F. V. 1 May 2014 In : Cell cycle (Georgetown, Tex.). 13, 9, p. 1413-1423 11 p.

    Research output: Contribution to journalArticle

  123. Discrimination of bladder cancer cells from normal urothelial cells with high specificity and sensitivity: combined application of AFM and modulated Raman spectroscopy

    Canetta, E., Riches, A., Borger, E., Herrington, S., Dholakia, K. & Adya, A. K. May 2014 In : Acta Biomaterialia. 10, 5, p. 2043-2055

    Research output: Contribution to journalArticle

  124. Expression of CXCL10 is associated with response to radiotherapy and overall survival in squamous cell carcinoma of the tongue

    Rentoft, M., Coates, P. J., Loljung, L., Wilms, T., Laurell, G. & Nylander, K. May 2014 In : Tumor Biology. 35, 5, p. 4191-4198 8 p.

    Research output: Contribution to journalArticle

  125. Patch clamp studies of human sperm under physiological ionic conditions reveal three functionally and pharmacologically distinct cation channels

    Mansell, S. A., Publicover, S. J., Barratt, C. L. R. & Wilson, S. M. May 2014 In : Molecular Human Reproduction. 20, 5, p. 392-408 17 p.

    Research output: Contribution to journalArticle

  126. E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin

    MacKay, C., Carroll, E., Ibrahim, A. F. M., Garg, A., Inman, G. J., Hay, R. T. & Alpi, A. F. 15 Apr 2014 In : Cancer Research. 74, 8, p. 2246-2257 12 p.

    Research output: Contribution to journalArticle

  127. Lack of correlation of stem cell markers in breast cancer stem cells

    Liu, Y., Nenutil, R., Appleyard, M. V., Murray, K., Boylan, M., Thompson, A. M. & Coates, P. J. 15 Apr 2014 In : British Journal of Cancer. 110, 8, p. 2063-2071 9 p.

    Research output: Contribution to journalArticle

  128. Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

    Stiborová, M., Moserová, M., Černá, V., Indra, R., Dračínský, M., Šulc, M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H., Frei, E. & Arlt, V. M. 6 Apr 2014 In : Toxicology. 318, 1, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  129. A gender-sensitised weight loss and healthy living programme for overweight and obese men delivered by Scottish Premier League football clubs (FFIT): a pragmatic randomised controlled trial

    Hunt, K., Wyke, S., Gray, C. M., Anderson, A. S., Brady, A., Bunn, C., Donnan, P. T., Fenwick, E., Grieve, E., Lieshman, J., Miller, E., Mutrie, N., Rauchhaus, P., White, A. & Treweek, S. 5 Apr 2014 In : Lancet. 383, 9924, p. 1211-1221 11 p.

    Research output: Contribution to journalArticle

  130. Antibiotic treatments and microbes in the gut

    Macfarlane, S. Apr 2014 In : Environmental Microbiology. 16, 4, p. 919-924 6 p.

    Research output: Contribution to journalArticle

  131. Epigenetic profiles as defined signatures of xenobiotic exposure

    Thomson, J. P., Moggs, J. G., Wolf, C. R. & Meehan, R. R. Apr 2014 In : Mutation Research: Genetic Toxicology and Environmental Mutagenesis. 764-765, p. 3-9 7 p.

    Research output: Contribution to journalArticle

  132. What are the characteristics of breast cancers misclassified as benign by quantitative ultrasound shear wave elastography?

    Vinnicombe, S. J., Whelehan, P., Thomson, K., McLean, D., Purdie, C. A., Jordan, L. B., Hubbard, S. & Evans, A. J. Apr 2014 In : European Radiology. 24, 4, p. 921-926 6 p.

    Research output: Contribution to journalArticle

  133. Biopsy confirmation of metastatic sites in breast cancer patients: clinical impact and future perspectives

    Criscitiello, C., André, F., Thompson, A. M., De Laurentiis, M., Esposito, A., Gelao, L., Fumagalli, L., Locatelli, M., Minchella, I., Orsi, F., Goldhirsch, A. & Curigliano, G. 21 Mar 2014 In : Breast Cancer Research. 16, 2, 10 p., 205

    Research output: Contribution to journalArticle

  134. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  135. A standard for Faecal Immunochemical TesTs for Haemoglobin Evaluation Reporting (FITTER)

    Fraser, C. G., Allison, J. E., Young, G. P., Halloran, S. P. & Seaman, H. Mar 2014 In : Annals of Clinical Biochemistry. 51, 2, p. 301-302 2 p.

    Research output: Contribution to journalLetter

  136. BPAG1-e restricts keratinocyte migration through control of adhesion stability

    Michael, M., Begum, R., Fong, K., Pourreyrone, C., South, A. P., McGrath, J. A. & Parsons, M. Mar 2014 In : Journal of Investigative Dermatology. 134, 3, p. 773-782 10 p.

    Research output: Contribution to journalArticle

  137. Pain identifies squamous cell carcinoma in organ transplant recipients: The SCOPE-ITSCC PAIN study

    Bouwes Bavinck, J. N. , Harwood, C. A. , Genders, R. E. , Wisgerhof, H. C. , Plasmeijer, E. I. , Mitchell, L. , Olasz, E. B. , Mosel, D. D. , Pokorney, M. S. , Serra, A. L. , Feldmeyer, L. , Baumann Conzett, K. , Piaserico, S. , Belloni Fortina, A. , Jahn, K. , Geusau, A. , Gerritsen, M. J. P. , Seçkin, D. , Güleç, A. T. , Cetkovská, P. & 4 others Ricar, J., Imko-Walczuk, B., Proby, C. M. & Hofbauer, G. F. L. Mar 2014 In : American Journal of Transplantation. 14, 3, p. 668-676 9 p.

    Research output: Contribution to journalArticle

  138. Signalling pathways in succinate dehydrogenase B-associated renal carcinoma

    Fleming, S., Mayer, N. J., Vlatkovic, L. J., McLean, J., McConachie, M. & Baty, D. Mar 2014 In : Histopathology. 64, 4, p. 477-483 7 p.

    Research output: Contribution to journalArticle

  139. Translational evidence on the role of Src kinase and activated Src kinase in invasive breast cancer

    Elsberger, B. Mar 2014 In : Critical Reviews in Oncology/Hematology. 89, 3, p. 343-351 9 p.

    Research output: Contribution to journalArticle

  140. Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes

    Dayal, J. H. S., Cole, C. L., Pourreyron, C., Watt, S. A., Lim, Y. Z., Salas-Alanis, J. C., Murrell, D. F., McGrath, J. A., Stieger, B., Jahoda, C., Leigh, I. M. & South, A. P. 15 Feb 2014 In : Journal of Cell Science. 127, 4, p. 740-751 12 p.

    Research output: Contribution to journalArticle

  141. A Targeted in Vivo SILAC Approach for Quantification of Drug Metabolism Enzymes: Regulation by the Constitutive Androstane Receptor

    Macleod, A. K., Zang, T., Riches, Z., Henderson, C. J., Wolf, C. R. & Huang, J. T-J. 7 Feb 2014 In : Journal of Proteome Research. 13, 2, p. 866-874 9 p.

    Research output: Contribution to journalArticle

  142. Nrf2 affects the efficiency of mitochondrial fatty acid oxidation

    Ludtmann, M. H. R., Angelova, P. R., Zhang, Y., Abramov, A. Y. & Dinkova-Kostova, A. T. 1 Feb 2014 In : Biochemical Journal. 457, 3, p. 415-424 10 p.

    Research output: Contribution to journalArticle

  143. Prognostic and therapeutic impact of Argininosuccinate Synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging

    Allen, M. D. , Luong, P. , Hudson, C. , Leyton, J. , Delage, B. , Ghazaly, E. , Cutts, R. , Yuan, M. , Syed, N. , Lo Nigro, C. , Lattanzio, L. , Chmielewska-Kassassir, M. , Tomlinson, I. , Roylance, R. , Whitaker, H. C. , Warren, A. Y. , Neal, D. , Frezza, C. , Beltran, L. , Jones, L. J. & 13 others Chelala, C., Wu, B-W., Bomalaski, J. S., Jackson, R. C., Lu, Y-J., Crook, T., Lemoine, N. R., Mather, S., Foster, J., Sosabowski, J., Avril, N., Li, C-F. & Szlosarek, P. W. 1 Feb 2014 In : Cancer Research. 74, 3, p. 896-907 12 p.

    Research output: Contribution to journalArticle

  144. Psychological, surgical, and sociodemographic predictors of pain outcomes after breast cancer surgery: a population-based cohort study

    Bruce, J., Thornton, A. J., Powell, R., Johnston, M., Wells, M., Heys, S. D., Thompson, A. M., Cairns Smith, W., Chambers, A. W. & Scott, N. W. Feb 2014 In : PAIN. 155, 2, p. 232-243 12 p.

    Research output: Contribution to journalArticle

  145. Responses to ionising radiation mediated by inflammatory mechanisms

    Mukherjee, D., Coates, P. J., Lorimore, S. A. & Wright, E. G. Feb 2014 In : Journal of Pathology. 232, 3, p. 289-299 11 p.

    Research output: Contribution to journalScientific review

  146. Results of a randomized controlled trial to promote physical activity behaviours in mothers with young children

    Monteiro, S. M. D. R., Jancey, J., Dhaliwal, S. S., Howat, P. A., Burns, S., Hills, A. P. & Anderson, A. S. Feb 2014 In : Preventive Medicine. 59, p. 12-18 7 p.

    Research output: Contribution to journalArticle

  147. Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-a randomised trial

    Vaidya, J. S. , Wenz, F. , Bulsara, M. , Tobias, J. S. , Joseph, D. J. , Keshtgar, M. , Flyger, H. L. , Massarut, S. , Alvarado, M. , Saunders, C. , Eiermann, W. , Metaxas, M. , Sperk, E. , Sütterlin, M. , Brown, D. , Esserman, L. , Roncadin, M. , Thompson, A. , Dewar, J. A. , Holtveg, H. M. R. & 9 others Pigorsch, S., Falzon, M., Harris, E., Matthews, A., Brew-Graves, C., Potyka, I., Corica, T., Williams, N. R. & Baum, M. Feb 2014 In : Lancet. 383, 9917, p. 603-613 11 p.

    Research output: Contribution to journalArticle

  148. Tumour bed clip localisation for targeted breast radiotherapy: Compliance is proportional to trial-related research activity: Tumour bed clip localisation in breast radiotherapy

    Kirwan, C. C., Al Sarakbi, W., Loncaster, J., Chan, H. Y., Thompson, A. M. & Wishart, G. C. Feb 2014 In : European Journal of Surgical Oncology. 40, 2, p. 158-162

    Research output: Contribution to journalArticle

  149. Grow₂: The HIF system, energy homeostasis and the cell cycle

    Moniz, S., Biddlestone, J. & Rocha, S. 10 Jan 2014 In : Histology and Histopathology.

    Research output: Contribution to journalArticle

  150. Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation

    Zhang, Y., Dayalan Naidu, S., Samarasinghe, K., Van Hecke, G. C., Pheely, A., Boronina, T. N., Cole, R. N., Benjamin, I. J., Cole, P. A., Ahn, Y-H. & Dinkova-Kostova, A. T. 7 Jan 2014 In : British Journal of Cancer. 110, 1, p. 71-82 12 p.

    Research output: Contribution to journalArticle

  151. A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice

    Henderson, C. J., McLaughlin, L. A., Finn, R. D., Ronseaux, S., Kapelyukh, Y. & Wolf, C. R. Jan 2014 In : Drug Metabolism and Disposition. 42, 1, p. 70-77 8 p.

    Research output: Contribution to journalArticle

  152. Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer?

    Evans, A., Rauchhaus, P., Whelehan, P., Thomson, K., Purdie, C. A., Jordan, L. B., Michie, C. O., Thompson, A. & Vinnicombe, S. Jan 2014 In : Breast Cancer Research and Treatment. 143, 1, p. 153-157 5 p.

    Research output: Contribution to journalArticle

  153. Interpretation of EUROCARE-5

    Munro, A. J. Jan 2014 In : Lancet Oncology. 15, 1, p. 2-3 2 p.

    Research output: Contribution to journalComment/debate

  154. Patterns of uptake in a biennial faecal occult blood test screening programme for colorectal cancer

    Steele, R. J. C., McClements, P. L., Libby, G., Carey, F. A. & Fraser, C. . G. Jan 2014 In : Colorectal Disease. 16, 1, p. 28-32 5 p.

    Research output: Contribution to journalArticle

  155. Progression, interobserver agreement, and malignancy rate in complex renal cysts (≥Bosniak category IIF)

    El-Mokadem, I., Budak, M., Pillai, S., Lang, S., Doull, R., Goodman, C. & Nabi, G. Jan 2014 In : Urologic Oncology: Seminars and Original Investigations. 32, 1, p. 24.e21-e27 7 p.

    Research output: Contribution to journalArticle

  156. CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations

    Province, M. A. , Goetz, M. P. , Brauch, H. , Flockhart, D. A. , Hebert, J. M. , Whaley, R. , Suman, V. J. , Schroth, W. , Winter, S. , Zembutsu, H. , Mushiroda, T. , Newman, W. G. , Lee, M-T. M. , Ambrosone, C. B. , Beckmann, M. W. , Choi, J-Y. , Dieudonné, A-S. , Fasching, P. A. , Ferraldeschi, R. , Gong, L. & 34 others Haschke-Becher, E., Howell, A., Jordan, L. B., Hamann, U., Kiyotani, K., Krippl, P., Lambrechts, D., Latif, A., Langsenlehner, U., Lorizio, W., Neven, P., Nguyen, A. T., Park, B-W., Purdie, C. A., Quinlan, P., Renner, W., Schmidt, M., Schwab, M., Shin, J-G., Stingl, J. C., Wegman, P., Wingren, S., Wu, A. H. B., Ziv, E., Zirpoli, G., Thompson, A. M., Jordan, V. C., Nakamura, Y., Altman, R. B., Ames, M. M., Weinshilboum, R. M., Eichelbaum, M., Ingle, J. N. & Klein, T. E. 2014 In : Clinical Pharmacology & Therapeutics. 95, 2, p. 216-227 12 p.

    Research output: Contribution to journalArticle

  157. 3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: potential candidates for chemoprevention

    Nagle, A. A., Reddy, S. A., Bertrand, H., Tajima, H., Dang, T-M., Wong, S-C., Hayes, J. D., Wells, G. & Chew, E-H. 2014 In : ChemMedChem. 9, 8, p. 1763-1774 12 p.

    Research output: Contribution to journalArticle

  158. A survey of reporting of colorectal cancer in Scotland: compliance with guidelines and effect of proforma reporting

    Woods, Y. L., Mukhtar, S., McClements, P., Lang, J., Steele, R. J. & Carey, F. A. 2014 In : Journal of Clinical Pathology. 67, p. 499-505 7 p.

    Research output: Contribution to journalArticle

  159. Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters

    Loughery, J., Cox, M., Smith, L. M. & Meek, D. W. 2014 In : Nucleic Acids Research. 42, 12, p. 7666-7680 15 p.

    Research output: Contribution to journalArticle

  160. Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolism

    Scheer, N., McLaughlin, L. A., Rode, A., MacLeod, A. K., Henderson, C. J. & Wolf, C. R. 2014 In : Drug Metabolism and Disposition. 42, 6, p. 1022-1030 9 p.

    Research output: Contribution to journalArticle

  161. Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling

    Spender, L. C. & Inman, G. J. 2014 In : Cancer Management and Research. 6, p. 27-38 12 p.

    Research output: Contribution to journalScientific review

  162. Distinct phosphatases antagonize the p53 response in different phases of the cell cycle

    Shaltiel, I. A., Aprelia, M., Saurin, A. T., Chowdhury, D., Kops, G. J. P. L., Voest, E. E. & Medema, R. H. 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 20, p. 7313-7318 6 p.

    Research output: Contribution to journalArticle

  163. Evaluating adaptation options of microcirculatory-tissue systems based on the physiological link of nutritive blood flow and redox ratio

    Krupatkin, A. I., Sidorov, V. V., Dremin, V. V., Dunaev, A. V., Novikova, I. N., Zhu, S., Nabi, G., Litvinova, K. S., Baklanova, A. P., Bakshaliev, R. M. & Ravcheev, S. A. 2014 Saratov Fall Meeting 2014 : Optical Technologies in Biophysics and Medicine XVI; Laser Physics and Photonics XVI; and Computational Biophysics. Genina, E. A., Derbov, V. L., Larin, K. V., Postnov, D. E. & Tuchin, V. V. (eds.). Bellingham: SPIE-International Society for Optical Engineering, 944803. (Proceedings of SPIE; vol. 9448)(Progress in Biomedical Optics and Imaging; vol. 16, no. 53)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  164. High levels of type VII collagen expression in RDEB cSCC keratinocytes increases PI3K and MAPK signalling, cell migration and invasion

    Pourreyron, C., Chen, M., McGrath, J. A., Salas-Alanis, J. C., South, A. P. & Leigh, I. M. 2014 In : British Journal of Dermatology. 170, 6, p. 1256-1265 11 p.

    Research output: Contribution to journalArticle

  165. How detection of epigenetic alterations of blood-borne DNA could improve melanoma diagnosis

    Hatzimichael, E., Syed, N., Lo Nigro, C., Rao, B. & Crook, T. 2014 In : Expert Review of Molecular Diagnostics. 14, 6, p. 639-642 4 p.

    Research output: Contribution to journalArticle

  166. Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-seq and ESTs

    Schurch, N. J., Cole, C., Sherstnev, A., Song, J., Duc, C., Storey, K. G., McLean, W. H. I., Brown, S. J., Simpson, G. G. & Barton, G. J. 2014 In : PLoS ONE. 9, 4, e94270

    Research output: Contribution to journalArticle

  167. In vivo regulation of human glutathione transferase GSTP by chemopreventive agents

    Henderson, C. J., McLaren, A. W. & Wolf, C. R. 2014 In : Cancer Research. p. 4378 1 p.

    Research output: Contribution to journalArticle

  168. Inherited epidermolysis bullosa: updated recommendations on diagnosis and classification

    Leigh, I. & 20 others Fine, J-D., Bruckner-Tuderman, L., Eady, R. A. J., Bauer, E. A., Bauer, J. W., Has, C., Heagerty, A., Hintner, H., Hovnanian, A., Jonkman, M. F., Marinkovich, M. P., Martinez, A. E., McGrath, J. A., Mellerio, J. E., Moss, C., Murrell, D. F., Shimizu, H., Uitto, J., Woodley, D. & Zambruno, G. 2014 In : Journal of the American Academy of Dermatology. 70, 6, p. 1103-1126 24 p.

    Research output: Contribution to journalArticle

  169. Investigating tissue respiration and skin microhaemocirculation under adaptive changes and the synchronization of blood flow and oxygen saturation rhythms

    Dunaev, A. V., Sidorov, V. V., Krupatkin, A. I., Rafailov, I. E., Palmer, S. G., Stewart, N. A., Sokolovski, S. G. & Rafailov, E. U. 2014 In : Physiological Measurement. 35, 4, p. 607-621 15 p.

    Research output: Contribution to journalArticle

  170. Kindlin-3 in the immune system

    Fagerholm, S. C., Lek, H. S. & Morrison, V. L. 2014 In : American Journal of Clinical and Experimental Immunology. 3, 1, p. 37-42 6 p.

    Research output: Contribution to journalArticle

  171. Leucoerythroblastic anaemia, abnormal bone scan and prostate cancer with a primary haematological diagnosis

    Preston, G., Meiklejohn, D. & Thomas, N. 2014 In : British Journal of Haematology. 1 p.

    Research output: Contribution to journalArticle

  172. Leukaemia and lymphoma: why has survival improved?

    Munro, A. J. 2014 In : Lancet Oncology. 15, 9, p. 906-907 2 p.

    Research output: Contribution to journalArticle

  173. Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: a case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

    Elcombe, C. R., Peffer, R. C., Wolf, D. C., Bailey, J., Bars, R., Bell, D., Cattley, R. C., Ferguson, S. S., Geter, D., Goetz, A., Goodman, J. I., Hester, S., Jacobs, A., Omiecinski, C. J., Schoeny, R., Xie, W. & Lake, B. G. 2014 In : Critical Reviews in Toxicology. 44, 1, p. 64-82 19 p.

    Research output: Contribution to journalArticle

  174. Optimization of PCR for quantification of simian immunodeficiency virus genomic RNA in plasma of rhesus macaques (Macaca mulatta) using armored RNA

    Monjure, C. J., Tatum, C. D., Panganiban, A. T., Arainga, M., Traina-Dorge, V., Marx, P. A. & Didier, E. S. 2014 In : Journal of Medical Primatology. 43, 1, p. 31-43 13 p.

    Research output: Contribution to journalArticle

  175. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane X receptors

    Henderson, C. J. , Wolf, C. R. & 24 others Luisier, R., Lempiäinen, H., Scherbichler, N., Braeuning, A., Geissler, M., Dubost, V., Müller, A., Scheer, N., Chibout, S-D., Hara, H., Picard, F., Theil, D., Couttet, P., Vitobello, A., Grenet, O., Grasl-Kraupp, B., Ellinger-Ziegelbauer, H., Thomson, J. P., Meehan, R. R., Elcombe, C. R., Schwarz, M., Moulin, P., Terranova, R. & Moggs, J. G. 2014 In : Toxicological Sciences. 139, 2, p. 501-511 11 p.

    Research output: Contribution to journalArticle

  176. Phosphoinositide 3-kinases upregulate system xc- via eukaryotic initiation factor 2α and activating transcription factor 4-A pathway active in glioblastomas and epilepsy

    Lewerenz, J., Baxter, P., Kassubek, R., Albrecht, P., Van Liefferinge, J., Westhoff, M-A., Halatsch, M-E., Karpel-Massler, G., Meakin, P. J., Hayes, J. D., Aronica, E., Smolders, I., Ludolph, A. C., Methner, A., Conrad, M., Massie, A., Hardingham, G. E. & Maher, P. 2014 In : Antioxidants & Redox Signaling. 20, 18, p. 2907-2922 16 p.

    Research output: Contribution to journalArticle

  177. Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling

    Atrih, A., Mudaliar, M. A. V., Zakikhani, P., Lamont, D. J., Huang, J. T-J., Bray, S. E., Barton, G., Fleming, S. & Nabi, G. 2014 In : British Journal of Cancer. 110, 6, p. 1622-1633 12 p.

    Research output: Contribution to journalArticle

  178. Recurrent dermatomyositis manifesting as a sign of recurrent transitional cell carcinoma of urinary bladder: long-term survival

    Fitzpatrick, J., Wallace, W. A., Lang, S., Aboumarzouk, O. M., Windsor, P. & Nabi, G. 2014 In : Urology Annals. 6, 3, p. 264-266 3 p.

    Research output: Contribution to journalArticle

  179. Significance of chromosome 9p status in renal cell carcinoma: a systematic review and quality of the reported studies

    El-Mokadem, I., Fitzpatrick, J., Rai, B., Cunningham, J., Pratt, N., Fleming, S. & Nabi, G. 2014 In : BioMed Research International. 2014, 11 p., 521380

    Research output: Contribution to journalArticle

  180. Socio-economic deprivation and outcomes following radical nephroureterectomy for clinically localized upper tract transitional cell carcinoma

    Mehta, R., Gillan, A. S., Ming, Z. Y., Rai, B. P., Byrne, D., Nabi, G. & Tayside Urological Cancers Network, Dundee, Scotland 2014 In : World Journal of Urology.

    Research output: Contribution to journalArticle

  181. The double loop mattress suture

    Biddlestone, J., Samuel, M., Creagh, T. & Ahmad, T. 2014 In : Wound Repair and Regeneration. 22, 3, p. 415-423 9 p.

    Research output: Contribution to journalArticle

  182. The Journal of Pathology: Clinical Research. A new step in the evolution of publishing in pathology

    Hall, P. & Herrington, S. 2014 In : Journal of Pathology: Clinical Research. 2 p.

    Research output: Contribution to journalEditorial

  183. Tissue engineering of tumor stromal microenvironment with application to cancer cell invasion

    Ng, Y-Z. & South, A. P. 2014 In : JoVE: Journal of Visualized Experiments. 85, e51321

    Research output: Contribution to journalArticle

  184. Uncovering the role of p53 splice variants in human malignancy: a clinical perspective

    Surget, S., Khoury, M. P. & Bourdon, J-C. 2014 In : OncoTargets and Therapy. 7, p. 57-68 12 p.

    Research output: Contribution to journalArticle

  185. Vemurafenib phototoxicity in HaCaT cells is not linked to changes in intracellular porphyrins

    Woods, J., Ferguson, J., Kalra, S., Degabriele, A., Gardner, J., Valentine, R. & Ferguson, J. 2014

    Research output: Contribution to conferencePoster

  186. Meeting the challenges of recruitment to multicentre, community-based, lifestyle-change trials: a case study of the BeWEL trial

    Treweek, S., Wilkie, E., Craigie, A. M., Caswell, S., Thompson, J., Steele, R. J. C., Stead, M. & Anderson, A. S. 18 Dec 2013 In : Trials. 14, 11 p., 436

    Research output: Contribution to journalArticle

  187. Infrared laser pulse triggers increased singlet oxygen production in tumour cells

    Sokolovski, S. G., Zolotovskaya, S. A., Goltsov, A., Pourreyron, C., South, A. P. & Rafailov, E. U. 12 Dec 2013 In : Scientific Reports. 3, 3484

    Research output: Contribution to journalArticle

  188. p53-Based cyclotherapy: exploiting the 'guardian of the genome' to protect normal cells from cytotoxic therapy

    Rao, B., Lain, S. & Thompson, A. M. 10 Dec 2013 In : British Journal of Cancer. 109, 12, p. 2954-2958 5 p.

    Research output: Contribution to journalArticle

  189. Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

    Ismail, H. M., O'Neill, P. M., Hong, D. W., Finn, R. D., Henderson, C. J., Wright, A. T., Cravatt, B. F., Hemingway, J. & Paine, M. J. I. 3 Dec 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19766-19771 6 p.

    Research output: Contribution to journalArticle

  190. A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

    Brown, S. J. & 32 others Weidinger, S., Willis-Owen, S. A. G., Kamatani, Y., Baurecht, H., Morar, N., Liang, L., Edser, P., Street, T., Rodriguez, E., O'Regan, G. M., Beattie, P., Fölster-Holst, R., Franke, A., Novak, N., Fahy, C. M., Winge, M. C. G., Kabesch, M., Illig, T., Heath, S., Söderhäll, C., Melén, E., Pershagen, G., Kere, J., Bradley, M., Lieden, A., Nordenskjold, M., Harper, J. I., McLean, W. H. I., Cookson, W. O. C., Lathrop, G. M., Irvine, A. D. & Moffatt, M. F. Dec 2013 In : Human Molecular Genetics. 22, 23, p. 4841-4856 16 p.

    Research output: Contribution to journalArticle

  191. Generation and utility of genetically humanized mouse models

    Scheer, N., Snaith, M., Wolf, C. R. & Seibler, J. Dec 2013 In : Drug Discovery Today. 18, 23-24, p. 1200-1211 12 p.

    Research output: Contribution to journalArticle

  192. MHR celebration issue in tribute to Professor Sir Robert Edwards

    Barratt, C. L. R. Dec 2013 In : Molecular Human Reproduction. 19, 12, p. 783-784 2 p.

    Research output: Contribution to journalEditorial

  193. Porphyrin profile in four human cell lines after supplementation with 5-aminolaevulinic acid and its methyl ester

    Barron, G. A., Valentine, R., Moseley, H., Brancaleon, L., Hill, C. & Woods, J. A. Dec 2013 In : Photodiagnosis and Photodynamic Therapy. 10, 4, p. 654-663 10 p.

    Research output: Contribution to journalArticle

  194. The design and optimization of RNA trans-splicing molecules for skin cancer therapy

    Gruber, C., Koller, U., Murauer, E. M., Hainzl, S., Hüttner, C., Kocher, T., South, A. P., Hintner, H. & Bauer, J. W. Dec 2013 In : Molecular Oncology. 7, 6, p. 1056-1068 13 p.

    Research output: Contribution to journalArticle

  195. Can shear-wave elastography predict response to neoadjuvant chemotherapy in women with invasive breast cancer?

    Evans, A., Armstrong, S., Whelehan, P., Thomson, K., Rauchhaus, P., Purdie, C., Jordan, L., Jones, L., Thompson, A. & Vinnicombe, S. 26 Nov 2013 In : British Journal of Cancer. 109, 11, p. 2798-2802 5 p.

    Research output: Contribution to journalArticle

  196. A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways

    Gan, F-F., Leng, H., Ang, X., Reddy, S. A., Lee, S. S-H., Yang, H., Tan, S-H., Hayes, J. D., Chui, W-K. & Chew, E-H. 1 Nov 2013 In : Toxicology and Applied Pharmacology. 272, 3, p. 852-862 11 p.

    Research output: Contribution to journalArticle

  197. Human papillomavirus multiplex ligation-dependent probe amplification assay for the assessment of viral load, integration, and gain of telomerase-related genes in cervical malignancies

    Theelen, W., Litjens, R. J. N. T. M., Vinokurova, S., Haesevoets, A., Reijans, M., Simons, G., Smedts, F., Herrington, C. S., Ramaekers, F. C. S., von Knebel Doeberitz, M., Speel, E-J. M. & Hopman, A. H. N. Nov 2013 In : Human Pathology. 44, 11, p. 2410-2418

    Research output: Contribution to journalArticle

  198. Weight management for overweight and obese men delivered through professional football clubs: a pilot randomized trial

    Gray, C. M., Hunt, K., Mutrie, N., Anderson, A. S., Treweek, S. & Wyke, S. 30 Oct 2013 In : International Journal of Behavioral Nutrition and Physical Activity. 10, October, 121

    Research output: Contribution to journalArticle

  199. Classification and immunohistochemical scoring of breast tissue microarray spots

    Amaral, T., McKenna, S. J., Robertson, K. & Thompson, A. Oct 2013 In : IEEE Transactions on Biomedical Engineering. 60, 10, p. 2806-2814 9 p.

    Research output: Contribution to journalArticle

  200. Handling and staging of renal cell carcinoma: the International Society of Urological Pathology Consensus (ISUP) conference recommendations

    Trpkov, K., Grignon, D. J., Bonsib, S. M., Amin, M. B., Billis, A., Lopez-Beltran, A., Samaratunga, H., Tamboli, P., Delahunt, B., Egevad, L., Montironi, R., Srigley, J. R. & ISUP Renal Tumor Panel Oct 2013 In : American Journal of Surgical Pathology. 37, 10, p. 1505–1517 13 p.

    Research output: Contribution to journalArticle

  201. Impact of multiple deprivations on detection, progression and interventions in small renal masses (less than 4 cm) in a population based study

    Leonard, M., Tait, C. D., Gillan, A. S., Rai, B. P., Byrne, D. J. & Nabi, G. Oct 2013 In : European Journal of Surgical Oncology. 39, 10, p. 1157-1163 7 p.

    Research output: Contribution to journalArticle

  202. Pattern of brain metastatic disease according to HER-2 and ER receptor status in breast cancer patients

    Lekanidi, K., Evans, A. L., Shah, J., Jaspan, T., Baker, L. & Evans, A. J. Oct 2013 In : Clinical Radiology. 68, 10, p. 1070-1073 4 p.

    Research output: Contribution to journalArticle

  203. Renal tumors: diagnostic and prognostic biomarkers

    Tan, P. H., Cheng, L., Rioux-Leclercq, N., Merino, M. J., Netto, G., Reuter, V. E., Shen, S. S., Grignon, D. J., Montironi, R., Egevad, L., Srigley, J. R., Delahunt, B., Moch, H. & ISUP Renal Tumor Panel Oct 2013 In : American Journal of Surgical Pathology. 37, 10, p. 1518–1531 14 p.

    Research output: Contribution to journalArticle

  204. Sentinel lymph node biopsy for cutaneous malignant melanoma-outcomes of 199 consecutive cases

    Carpenter, F., Teo, I., Rose, A. & Hough, M. Oct 2013 In : International Journal of Surgery . 11, 8, p. 680-681 2 p., 0808

    Research output: Contribution to journalMeeting abstract

  205. Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double-blind, placebo-controlled crossover study

    Macfarlane, S., Cleary, S., Bahrami, B., Reynolds, N. & Macfarlane, G. T. Oct 2013 In : Alimentary Pharmacology & Therapeutics. 38, 7, p. 804-816 13 p.

    Research output: Contribution to journalArticle

  206. The International Society of Urological Pathology (ISUP) grading system for renal cell carcinoma and other prognostic parameters

    Delahunt, B., Cheville, J. C., Martignoni, G., Humphrey, P. A., Magi-Galluzzi, C., McKenney, J., Egevad, L., Algaba, F., Moch, H., Grignon, D. J., Montrioni, R., Srigley, J. R. & ISUP Renal Tumor Panel Oct 2013 In : American Journal of Surgical Pathology. 37, 10, p. 1490–1504 15 p.

    Research output: Contribution to journalArticle

  207. The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia

    Srigley, J. R., Delahunt, B., Eble, J. N., Egevad, L., Epstein, J. I., Grignon, D., Hes, O., Moch, H., Montironi, R., Tickoo, S. K., Zhou, M., Argani, P. & ISUP Renal Tumor Panel Oct 2013 In : American Journal of Surgical Pathology. 37, 10, p. 1469-89 21 p.

    Research output: Contribution to journalArticle

  208. The one-stop clinic in plastic surgery - development of a novel proforma

    Teo, I., Rose, A. & Hough, M. Oct 2013 In : International Journal of Surgery . 11, 8, p. 680 1 p., 0807

    Research output: Contribution to journalMeeting abstract

  209. Targeted manipulation of apoptotic pathways by using High Intensity Focused Ultrasound in cancer treatment

    Saliev, T., Feril, L. B., Nabi, G. & Melzer, A. 28 Sep 2013 In : Cancer Letters. 338, 2, p. 204-208 5 p.

    Research output: Contribution to journalArticle

  210. Cytochrome P450 CYP1B1 Interacts with 8-Methoxypsoralen (8-MOP) and Influences Psoralen-Ultraviolet A (PUVA) Sensitivity

    Deeni, Y. Y., Ibbotson, S. H., Woods, J. A., Wolf, C. R. & Smith, G. 23 Sep 2013 In : PLoS ONE. 8, 9, e75494

    Research output: Contribution to journalArticle

  211. The relationship between lymphocyte subsets and clinico-pathological determinants of survival in patients with primary operable invasive ductal breast cancer

    Mohammed, Z. M. A., Going, J. J., Edwards, J., Elsberger, B. & McMillan, D. C. 17 Sep 2013 In : British Journal of Cancer. 109, 6, p. 1676-1684 9 p.

    Research output: Contribution to journalArticle

  212. p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer

    Bourdon, J-C. & 20 others Marcel, V., Ghayad, S. E., Belin, S., Therizols, G., Morel, A-P., Solano-Gonzàlez, E., Vendrell, J. A., Hacot, S., Mertani, H. C., Albaret, M. A., Jordan, L., Thompson, A., Tafer, Y., Cong, R., Bouvet, P., Saurin, J-C., Catez, F., Prats, A-C., Puisieux, A. & Diaz, J-J. 9 Sep 2013 In : Cancer Cell. 24, 3, p. 318-330 13 p.

    Research output: Contribution to journalArticle

  213. Differential sensitivity in cell lines to photodynamic therapy in combination with ABCG2 inhibition

    Barron, G. A., Moseley, H. & Woods, J. A. 5 Sep 2013 In : Journal of Photochemistry and Photobiology B: Biology. 126, p. 87-96 10 p.

    Research output: Contribution to journalArticle

  214. Understanding Eating Behaviour and Lifestyle Issues in Women: Implications for Obesity Development and Prevention

    Anderson, A. S. & Craigie, A. M. 4 Sep 2013 Obesity: A ticking time bomb for reproductive health. Mahmood, T. A. & Arulkumaran, S. (eds.). Elsevier, p. 597-606 10 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  215. Computational analyses of an evolutionary arms race between mammalian immunity mediated by immunoglobulin A and its subversion by bacterial pathogens

    Pinheiro, A., Woof, J. M., Abi-Rached, L., Parham, P. & Esteves, P. J. 3 Sep 2013 In : PLoS ONE. 8, 9, 9 p., e73934

    Research output: Contribution to journalArticle

  216. Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin

    Voss, M., Campbell, K., Saranzewa, N., Campbell, D. G., Hastie, C. J., Peggie, M. W., Martin-Granados, C., Prescott, A. R. & Cohen, P. T. W. 1 Sep 2013 In : Cell Cycle. 12, 17, p. 2876-2887 12 p.

    Research output: Contribution to journalArticle

  217. Centralization of services and reduction of adverse events in pancreatic cancer surgery

    Young, J., Thompson, A., Tait, I., Waugh, L. & McPhillips, G. Sep 2013 In : World Journal of Surgery. 37, 9, p. 2229-2233 5 p.

    Research output: Contribution to journalArticle

  218. Translocation renal cell carcinomas: an evolving entity and a member of the microphthalmia transcription factor-associated family of tumors

    Bambury, R. M., Battley, J. E., McCarthy, A., Brady, C., O'Reilly, S., Kelly, P. J., O'Brien, F., Sweeney, P., Fleming, S., Mayer, N. J. & Power, D. G. Sep 2013 In : Clinical Genitourinary Cancer. 11, 3, p. 357-361 5 p.

    Research output: Contribution to journalArticle

  219. Transrectal quantitative shear wave elastography in the detection and characterisation of prostate cancer

    Ahmad, S., Cao, R., Varghese, T., Bidaut, L. & Nabi, G. Sep 2013 In : Surgical Endoscopy. 27, 9, p. 3280-3287 8 p.

    Research output: Contribution to journalArticle

  220. The β2 integrin–kindlin-3 interaction is essential for T-cell homing but dispensable for T-cell activation in vivo

    Morrison, V. L., MacPherson, M., Savinko, T., San Lek, H., Prescott, A. & Fagerholm, S. C. 22 Aug 2013 In : Blood. 122, 8, p. 1428-1436 9 p.

    Research output: Contribution to journalArticle

  221. Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

    Holmström, K. M., Baird, L., Zhang, Y., Hargreaves, I., Chalasani, A., Land, J. M., Stanyer, L., Yamamoto, M., Dinkova-Kostova, A. T. & Abramov, A. Y. 15 Aug 2013 In : Open Biology. 2, 8, p. 761-770 10 p.

    Research output: Contribution to journalArticle

  222. Influenza NS1 interacts with p53 and alters its binding to p53-responsive genes, in a promoter-dependent manner

    Terrier, O., Diederichs, A., Dubois, J., Cartet, G., Lina, B., Bourdon, J-C. & Rosa-Calatrava, M. 13 Aug 2013 In : FEBS Letters. 587, 18, p. 2965-2971 7 p.

    Research output: Contribution to journalArticle

  223. Phosphorylation of Crm1 by CDK1-cyclin-B promotes Ran-dependent mitotic spindle assembly

    Wu, Z., Jiang, Q., Clarke, P. R. & Zhang, C. 1 Aug 2013 In : Journal of Cell Science. 126, 15, p. 3417-3428 12 p.

    Research output: Contribution to journalArticle

  224. A facile and real-time spectroscopic method for biofluid analysis in point-of-care diagnostics

    Kumar, R., Singh, G. P., Barman, I., Dingari, N. C. & Nabi, G. Aug 2013 In : Bioanalysis. 5, 15, p. 1853-1861 9 p.

    Research output: Contribution to journalArticle

  225. Looking back on the birth of DEAD-box RNA helicases

    Linder, P. & Fuller-Pace, F. Aug 2013 In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 8, p. 750-755 6 p.

    Research output: Contribution to journalArticle

  226. Obesity and lifestyle advice in colorectal cancer survivors: How well are clinicians prepared?

    Anderson, A. S., Caswell, S., Wells, M. & Steele, R. J. C. Aug 2013 In : Colorectal Disease. 15, 8, p. 949-957 19 p.

    Research output: Contribution to journalArticle

  227. Preface

    Linder, P. & Fuller-Pace, F. Aug 2013 In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 8, p. 749 1 p.

    Research output: Contribution to journalEditorial

  228. The DEAD box proteins DDX5 (p68) and DDX17 (p72): Multi-tasking transcriptional regulators

    Fuller-Pace, F. V. Aug 2013 In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1829, 8, p. 756-763 8 p.

    Research output: Contribution to journalScientific review

  229. The effect of mammography pain on repeat participation in breast cancer screening: a systematic review

    Whelehan, P., Evans, A., Wells, M. & MacGillivray, S. Aug 2013 In : Breast. 22, 4, p. 389-394 6 p.

    Research output: Contribution to journalScientific review

  230. BMP9 is a proliferative and survival factor for human hepatocellular carcinoma cells

    Herrera, B., García-Álvaro, M., Cruz, S., Walsh, P., Fernández, M., Roncero, C., Fabregat, I., Sánchez, A. & Inman, G. J. 23 Jul 2013 In : PLoS ONE. 8, 7, e69535

    Research output: Contribution to journalArticle

  231. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

    Nicol, S. M., Bray, S. E., Derek Black, H., Lorimore, S. A., Wright, E. G., Lane, D. P., Meek, D. W., Coates, P. J. & Fuller-Pace, F. V. 18 Jul 2013 In : Oncogene. 32, 29, p. 3461-3469 9 p.

    Research output: Contribution to journalArticle

  232. Developing a standardized actinic keratosis assessment protocol

    Matin, R. N., Gaunt, P., McCartney, D. L., Ismail, F., Bowden, S. J., McGregor, J. M., Lear, J. T., Proby, C. M. & Harwood, C. A. Jul 2013 In : British Journal of Dermatology. 169, Suppl. 1, p. 101 1 p., BI05

    Research output: Contribution to journalMeeting abstract

  233. Evaluation of a nurse-led clinic for skin cancer awareness and surveillance of organ transplant recipients

    Mitchell, L., Gulati, A., McGregor, J. M., Proby, C. M. & Harwood, C. A. Jul 2013 In : British Journal of Dermatology. 169, Suppl. 1, p. 105 1 p., BI14

    Research output: Contribution to journalMeeting abstract

  234. Impact of skin cancers and premalignancies on the quality of life of organ transplant recipients

    Mitchell, L., Gulati, A., McGregor, J. M., Proby, C. M. & Harwood, C. A. Jul 2013 In : British Journal of Dermatology. 169, Suppl. 1, p. 101-102 2 p., BI06

    Research output: Contribution to journalMeeting abstract

  235. In Brief: cell senescence

    Coates, P. J. Jul 2013 In : Journal of Pathology. 230, 3, p. 239-240 2 p.

    Research output: Contribution to journalArticle

  236. Intracellular translocation and differential accumulation of cell-penetrating peptides in bovine spermatozoa: evaluation of efficient delivery vectors that do not compromise human sperm motility

    Jones, S., Lukanowska, M., Suhorutsenko, J., Oxenham, S., Barratt, C., Publicover, S., Copolovici, D. M., Langel, U. & Howl, J. Jul 2013 In : Human Reproduction. 28, 7, p. 1874-1889 16 p.

    Research output: Contribution to journalArticle

  237. Laparoscopic en bloc resection of ureter with a cuff of bladder during radical nephroureterectomy for lower ureteric tumors: a matched-paired analysis

    Gillan, A., Alexander, E., Townell, N. & Nabi, G. Jul 2013 In : Journal of Laparoendoscopic and Advanced Surgical Techniques. 23, 7, p. 626-631 6 p.

    Research output: Contribution to journalArticle

  238. Mitomycin C instillation following ureterorenoscopic laser ablation of upper urinary tract carcinoma

    Aboumarzouk, O. M., Somani, B., Ahmad, S., Nabi, G., Townell, N. & Kata, S. G. Jul 2013 In : Urology Annals. 5, 3, p. 184-189 6 p.

    Research output: Contribution to journalArticle

  239. p63 and nuclear factor-kB expression in primary cutaneous B-cell lymphoma: further evidence for pathogenetic heterogeneity

    Shukur, Z., Coates, P., Subtil, A., Kempf, W., Sahni, D. & Robson, A. Jul 2013 In : British Journal of Dermatology. 169, Suppl. 1, p. 87 1 p., DP04

    Research output: Contribution to journalMeeting abstract

  240. Prevalence and associated risk factors for actinic keratoses and actinic field change among renal transplant patients

    Wallingford, S., Proby, C. M., Vail, A., Russell, S., Lear, J. T. & Green, A. Jul 2013 In : British Journal of Dermatology. 169, Suppl. 1, p. 100-101 2 p., BI04

    Research output: Contribution to journalMeeting abstract

  241. Recruiting and retaining postpartum women from areas of social disadvantage in a weight-loss trial: an assessment of strategies employed in the WeighWell feasibility study

    Macleod, M., Craigie, A. M., Barton, K. L., Treweek, S., Anderson, A. S., Williams, B. & Weighwell Team Jul 2013 In : Maternal and Child Nutrition. 9, 3, p. 322-331 10 p.

    Research output: Contribution to journalArticle

  242. Mutant mice lacking the p53 C-terminal domain model telomere syndromes

    Simeonova, I., Jaber, S., Draskovic, I., Bardot, B., Fang, M., Bouarich-Bourimi, R., Lejour, V., Charbonnier, L., Soudais, C., Bourdon, J-C., Huerre, M., Londono-Vallejo, A. & Toledo, F. 27 Jun 2013 In : Cell Reports. 3, 6, p. 2046-2058 13 p.

    Research output: Contribution to journalArticle

  243. Open versus laparoscopic right hemicolectomy in the elderly population

    Quyn, A. J., Moussa, O., Millar, F., Smith, D. M. & Steele, R. J. C. 27 Jun 2013 In : World Journal of Gastrointestinal Surgery. 5, 6, p. 187-191 5 p.

    Research output: Contribution to journalArticle

  244. What is a virtual multidisciplinary team (vMDT)?

    Munro, A. J. & Swartzman, S. 25 Jun 2013 In : British Journal of Cancer. 108, 12, p. 2433-2441 9 p.

    Research output: Contribution to journalArticle

  245. Clinical outcomes using a faecal immunochemical test for haemoglobin as a first-line test in a national programme constrained by colonoscopy capacity

    Steele, R. J. C., McDonald, P. J., Digby, J., Brownlee, L., Strachan, J. A., Libby, G., McClements, P. L., Birrell, J., Carey, F. A., Diament, R. H., Balsitis, M. & Fraser, C. G. Jun 2013 In : United European Gastroenterology Journal. 1, 3, p. 198-205 8 p.

    Research output: Contribution to journalArticle

  246. Homeodomain-interacting protein kinase 2-dependent repression of myogenic differentiation is relieved by its caspase-mediated cleavage

    De La Vega, L., Hornung, J., Kremmer, E., Milanovic, M. & Lienhard Schmitz, M. Jun 2013 In : Nucleic Acids Research. 41, 11, p. 5731-5745 15 p.

    Research output: Contribution to journalArticle

  247. Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality?

    Blackett, K. L., Siddhi, S. S., Cleary, S., Steed, H., Miller, M. H., Macfarlane, S., Macfarlane, G. T. & Dillon, J. F. Jun 2013 In : Alimentary Pharmacology & Therapeutics. 37, 11, p. 1084-1092 9 p.

    Research output: Contribution to journalArticle

  248. Use of a faecal immunochemical test narrows current gaps in uptake for sex, age and deprivation in a bowel cancer screening programme

    Digby, J., McDonald, P. J., Strachan, J. A., Libby, G., Steele, R. J. C. & Fraser, C. G. Jun 2013 In : Journal of Medical Screening. 20, 2, p. 80-85 6 p.

    Research output: Contribution to journalArticle

  249. Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication

    Nakano, K., Ando, T., Yamagishi, M., Yokoyama, K., Ishida, T., Ohsugi, T., Tanaka, Y., Brighty, D. W. & Watanabe, T. Jun 2013 In : Microbes and Infection. 15, 6-7, p. 491-505 15 p.

    Research output: Contribution to journalArticle

  250. Generation and characterisation of keratin 7 (K7) knockout mice

    Sandilands, A., Smith, F. J. D., Lunny, D. P., Campbell, L. E., Davidson, K. M., MacCallum, S. F., Corden, L. D., Christie, L., Fleming, S., Lane, E. B. & McLean, W. H. I. 31 May 2013 In : PLoS ONE. 8, 5, 11 p., e64404

    Research output: Contribution to journalArticle

  251. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 24 May 2013 In : Journal of Biological Chemistry. 288, 21, p. 14698-14708 11 p.

    Research output: Contribution to journalArticle

  252. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 10 May 2013 In : Journal of Biological Chemistry. 288, 19, p. 13808-13820 13 p.

    Research output: Contribution to journalArticle

  253. Effects of antibiotics on bacterial species composition and metabolic activities in chemostats containing defined populations of human gut microorganisms

    Newton, D. F., Macfarlane, S. & Macfarlane, G. T. May 2013 In : Antimicrobial Agents and Chemotherapy. 57, 5, p. 2016-2025 10 p.

    Research output: Contribution to journalArticle

  254. Host microRNA molecular signatures associated with human H1N1 and H3N2 influenza A viruses reveal an unanticipated antiviral activity for miR-146a

    Terrier, O., Textoris, J., Carron, C., Marcel, V., Bourdon, J-C. & Rosa-Calatrava, M. May 2013 In : Journal of General Virology. 94, 5, p. 985-995 11 p.

    Research output: Contribution to journalArticle

  255. Laparoscopic Surgical Skills are Significantly Improved by the Use of a Portable Laparoscopic Simulator: Results of a Randomized Controlled Trial

    Johnston, T. J., Tang, B., Alijani, A., Tait, I., Steele, R. J., Ker, J., Nabi, G. & Surgical Simulation Group at the University of Dundee May 2013 In : World Journal of Surgery. 37, 5, p. 957-964 8 p.

    Research output: Contribution to journalArticle

  256. Methylated tissue factor pathway inhibitor 2 (TFPI2) DNA in serum is a biomarker of metastatic melanoma

    Nigro, C. L., Wang, H., McHugh, A., Lattanzio, L., Matin, R., Harwood, C., Syed, N., Hatzimichael, E., Briasoulis, E., Merlano, M., Evans, A., Thompson, A., Leigh, I., Fleming, C., Inman, G. J., Proby, C. & Crook, T. May 2013 In : Journal of Investigative Dermatology. 133, 5, p. 1278-1285 8 p.

    Research output: Contribution to journalArticle

  257. The use of steroids in acute tubulo-interstitial nephritis. A multicentre retrospective study

    Hetherington, L., Valluri, A., McQuarrie, E., Fleming, S., Geddes, C., Bell, S. & MacKinnon, B. May 2013 In : Nephrology Dialysis Transplantation. 28, supp. 1, p. i343-i343 1 p., MP145

    Research output: Contribution to journalMeeting abstract

  258. miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity

    Remenyi, J., van den Bosch, M. W. M., Palygin, O., Mistry, R. B., McKenzie, C., Macdonald, A., Hutvagner, G., Arthur, J. S. C., Frenguelli, B. G. & Pankratov, Y. 26 Apr 2013 In : PLoS ONE. 8, 4, 14 p., e62509

    Research output: Contribution to journalArticle

  259. The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression

    Bernard, H., Garmy-Susini, B., Ainaoui, N., Van Den Berghe, L., Peurichard, A., Javerzat, S., Bikfalvi, A., Lane, D. P., Bourdon, J. C. & Prats, A-C. 25 Apr 2013 In : Oncogene. 32, 17, p. 2150-2160 11 p.

    Research output: Contribution to journalArticle

  260. Improved sperm function / activity

    Barratt, C. & Wyatt, P. 18 Apr 2013 WO2013054111 A1

    Research output: Patent

  261. Cohort study of adherence to adjuvant endocrine therapy, breast cancer recurrence and mortality

    Makubate, B., Donnan, P. T., Dewar, J. A., Thompson, A. M. & McCowan, C. 16 Apr 2013 In : British Journal of Cancer. 108, 7, p. 1515-1524 10 p.

    Research output: Contribution to journalArticle

  262. p53 Protein Isoforms: Key Regulators in the Front Line of Pathogen Infections?

    Terrier, O., Bourdon, J-C. & Rosa-Calatrava, M. 4 Apr 2013 In : PLoS Pathogens. 9, 4, p. e1003246

    Research output: Contribution to journalArticle

  263. Complementation of juxtaglomerular cell granulation in Ren-1d null mice by human renin

    Buckley, C., Nelson, R., Sharp, M., Flemming, S., Kenyon, C., Mullins, L., Steppan, D. & Mullins, J. Apr 2013 In : FASEB Journal. 27, Suppl., 1 p., 1165.20

    Research output: Contribution to journalMeeting abstract

  264. NAD(P)H: Quinone oxidoreductase 1 inducer activity of some Saudi Arabian medicinal plants

    Shahat, A. A., Alsaid, M. S., Alyahya, M. A., Higgins, M. & Dinkova-Kostova, A. T. Apr 2013 In : Planta Medica. 79, 6, p. 459-464 6 p.

    Research output: Contribution to journalArticle

  265. Palliative care for patients with gastrointestinal cancer dying under surgical care: a case for acute palliative care units?

    Young, J. A., Waugh, L., McPhillips, G., Levack, P. & Thompson, A. M. Apr 2013 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 11, 2, p. 72-75 4 p.

    Research output: Contribution to journalArticle

  266. The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

    Alasmari, W., Barratt, C. L. R., Publicover, S. J., Whalley, K. M., Foster, E., Kay, V., Martins Da Silva, S. & Oxenham, S. K. Apr 2013 In : Human Reproduction. 28, 4, p. 866-876 11 p.

    Research output: Contribution to journalArticle

  267. Ubiquitin-proteasome system impairment and MPTP-induced oxidative stress in the brain of C57BL/6 wild-type and GSTP knockout mice

    Carvalho, A. N., Marques, C., Rodrigues, E., Henderson, C. J., Wolf, C. R., Pereira, P. & Gama, M. J. Apr 2013 In : Molecular Neurobiology. 47, 2, p. 662-72 11 p.

    Research output: Contribution to journalArticle

  268. Workplace dietary improvement initiatives ought not to be discouraged by modest returns from low-intensity interventions

    Mooney, J. D., Frank, J. & Anderson, A. S. Apr 2013 In : European Journal of Public Health. 23, 2, p. 193-194 2 p.

    Research output: Contribution to journalArticle

  269. Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b β2-integrin-dependent signaling

    McMillan, S. J., Sharma, R. S., McKenzie, E. J., Richards, H. E., Zhang, J., Prescott, A. & Crocker, P. R. 14 Mar 2013 In : Blood. 121, 11, p. 2084-2094 11 p.

    Research output: Contribution to journalArticle

  270. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 1 Mar 2013 In : Journal of Biological Chemistry. 288, 9, p. 6248-6258 11 p.

    Research output: Contribution to journalArticle

  271. Low faecal haemoglobin concentration potentially rules out significant colorectal disease

    McDonald, P. J., Digby, J., Innes, C., Strachan, J. A., Carey, F. A., Steele, R. J. C. & Fraser, C. G. Mar 2013 In : Colorectal Disease. 15, 3, p. e151-e159 9 p.

    Research output: Contribution to journalArticle

  272. Utility of prognostic genomic tests in breast cancer practice: The IMPAKT 2012 Working Group Consensus Statement

    Azim, H. A., Michiels, S., Zagouri, F., Delaloge, S., Filipits, M., Namer, M., Neven, P., Symmans, W. F., Thompson, A., Andre, F., Loi, S. & Swanton, C. Mar 2013 In : Annals of Oncology. 24, 3, p. 647-654 8 p.

    Research output: Contribution to journalArticle

  273. Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer

    Ohotski, J., Edwards, J., Elsberger, B., Watson, C., Orange, C., Mallon, E., Pyne, S. & Pyne, N. J. 1 Feb 2013 In : International Journal of Cancer. 132, 3, p. 605-616 12 p.

    Research output: Contribution to journalArticle

  274. Improved short term surgical outcomes in Scotland for oesophageal cancer

    Young, J. A., Shimi, S. M., Waugh, L., McPhillips, G. & Thompson, A. M. Feb 2013 In : European Journal of Surgical Oncology. 39, 2, p. 131-135 5 p.

    Research output: Contribution to journalArticle

  275. Interactions of Apoptotic Cells with Macrophages in Radiation-Induced Bystander Signaling

    Rastogi, S., Boylan, M., Wright, E. G. & Coates, P. J. Feb 2013 In : Radiation Research. 179, 2, p. 135-145 11 p.

    Research output: Contribution to journalArticle

  276. Microbial biofilms and gastrointestinal diseases

    von Rosenvinge, E. C., O'May, G. A., Macfarlane, S., Macfarlane, G. T. & Shirtliff, M. E. Feb 2013 In : Pathogens and Disease. 67, 1, p. 25-38 14 p.

    Research output: Contribution to journalArticle

  277. Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling

    Lambert, S. R., Mladkova, N., Gulati, A., Hamoudi, R., Purdie, K., Cerio, R., Leigh, I., Proby, C. & Harwood, C. A. 21 Jan 2013 In : British Journal of Cancer. 110, 2, p. 520-529 10 p.

    Research output: Contribution to journalArticle

  278. p68/DdX5 supports β-Catenin & RNAP II during androgen receptor mediated transcription in prostate cancer

    Clark, E. L., Hadjimichael, C., Temperley, R., Barnard, A., Fuller-Pace, F. V. & Robson, C. N. 17 Jan 2013 In : PLoS ONE. 8, 1, 10 p., e54150

    Research output: Contribution to journalArticle

  279. p53 is activated in response to disruption of the pre-mRNA splicing machinery

    Allende-Vega, N., Dayal, S., Agarwala, U., Sparks, A., Bourdon, J-C. & Saville, M. K. 3 Jan 2013 In : Oncogene. 32, 1, p. 1-14 14 p.

    Research output: Contribution to journalArticle

  280. A surveillance model for skin cancer in organ transplant recipients: A 22-year prospective study in an ethnically diverse population

    Harwood, C. A., Mesher, D., McGregor, J. M., Mitchell, L., Leedham-Green, M., Raftery, M., Cerio, R., Leigh, I. M., Sasieni, P. & Proby, C. M. Jan 2013 In : American Journal of Transplantation. 13, 1, p. 119-129 11 p.

    Research output: Contribution to journalArticle

  281. European guidelines for quality assurance in colorectal cancer screening and diagnosis: overview and introduction to the full supplement publication

    European Colorectal Cancer Screening Guidelines Working Group Jan 2013 In : Endoscopy. 45, 1, p. 51-59 9 p.

    Research output: Contribution to journalArticle

  282. NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology

    Riddick, D. S., Ding, X., Wolf, C. R., Porter, T. D., Pandey, A. V., Zhang, Q-Y., Gu, J., Finn, R. D., Ronseaux, S., McLaughlin, L. A., Henderson, C. J., Zou, L. & Flück, C. E. Jan 2013 In : Drug Metabolism and Disposition. 41, 1, p. 12-23 12 p.

    Research output: Contribution to journalArticle

  283. Physical activity and nutrition behavioural outcomes of a home-based intervention program for seniors: a randomized controlled trial

    Burke, L., Lee, A. H., Jancey, J., Xiang, L., Kerr, D. A., Howat, P. A., Hills, A. P. & Anderson, A. S. Jan 2013 In : International Journal of Behavioral Nutrition and Physical Activity. 10, 8 p., 14

    Research output: Contribution to journalArticle

  284. Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

    Dichtel-Danjoy, M-L., Ma, D., Dourlen, P., Chatelain, G., Napoletano, F., Robin, M., Corbet, M., Levet, C., Hafsi, H., Hainaut, P., Ryoo, H. D., Bourdon, J-C. & Mollereau, B. 2013 In : Cell Death & Differentiation. 20, 1, p. 108-116 9 p.

    Research output: Contribution to journalArticle

  285. A two gene serum epigenetic signature detects metastatic melanoma with high sensitivity and specificity

    Wang, H., McHugh, A., Matin, R., Fleming, C., Leigh, I., Harwood, C., Inman, G., Crook, T. & Proby, C. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S235 1 p., 1379

    Research output: Contribution to journalMeeting abstract

  286. Aminoglycosides and non-aminoglycosides suppress premature stop mutations and restore type VII collagen function in RDEB

    Wang, X. Y., Cogan, J., Hou, Y. P., Khilili, M., Paparisto, E., South, A. P., Woodley, D. T. & Chen, M. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S141 1 p., 831

    Research output: Contribution to journalMeeting abstract

  287. Anticipated regret to increase uptake of colorectal cancer screening in Scotland (ARTICS): study protocol for a randomised controlled trial

    O'Carroll, R. E., Steele, R. J. C., Libby, G., Brownlee, L. & Chambers, J. A. 2013 In : BMC Public Health. 13, p. 849

    Research output: Contribution to journalArticle

  288. Autoantibodies and decreased expression of the transcription factor ELF-3 together with increased chemokine pathways support an autoimmune phenotype and altered differentiation in lichen planus located in oral mucosa

    Danielsson, K., Boldrup, L., Rentoft, M., Coates, P. J., Ebrahimi, M., Nylander, E., Wahlin, Y. B. & Nylander, K. 2013 In : Journal of the European Academy of Dermatology and Venereology. 27, 11, p. 1410-1416 7 p.

    Research output: Contribution to journalArticle

  289. Beware using secular trends in deaths to judge effectiveness of breast screening

    Brewster, D. H., Bhatti, L. A., Thomson, C. S., Cameron, D. A. & Dewar, J. A. 2013 In : British Medical Journal. 347, 7916

    Research output: Contribution to journalLetter

  290. Can additional histopathological examination of ultrasound-guided axillary lymph node core biopsies improve preoperative diagnosis of primary breast cancer nodal metastasis?

    Mullen, R., Purdie, C. A., Jordan, L. B., McLean, D., Whelehan, P., Vinnicombe, S., Brown, D. C. & Evans, A. 2013 In : Clinical Radiology. 68, 7, p. 704-707 4 p.

    Research output: Contribution to journalArticle

  291. Characterisation of skin autofluorescence to establish its role in distinguishing between normal and diseased skin.

    Woods, J., Robinson, K., Moseley, H., Gardner, J. & Ibbotson, S. 2013 p. S209 1 p.

    Research output: Contribution to conferenceAbstract

  292. Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry

    Nekulova, M., Holcakova, J., Nenutil, R., Stratmann, R., Bouchalova, P., Müller, P., Mouková, L., Coates, P. J. & Vojtesek, B. 2013 In : Virchows Archiv. 11 p.

    Research output: Contribution to journalArticle

  293. Chemoprotection Against Cancer by Isothiocyanates: A Focus on the Animal Models and the Protective Mechanisms

    Dinkova-Kostova, A. T. 2013 Natural Products in Cancer Prevention and Therapy. Pezzuto, J. M. & Suh, N. (eds.). Berlin: Springer , p. 179-201 23 p. (Topics in Current Chemistry; vol. 329)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  294. Controlling how sperm swim: Ca2+signals, Ca2+stores and Ca2+channels

    Publicover, S., Correia, J., Alasmari, W. & Barratt, C. 2013 In : Human Reproduction. 28, S1, p. i20-i21 2 p.

    Research output: Contribution to journalMeeting abstract

  295. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

    Anderson, A. S. & 86 others Eccles, S. A., Aboagye, E. O., Ali, S., Armes, J., Berditchevski, F., Blaydes, J. P., Brennan, K., Brown, N. J., Bryant, H. E., Bundred, N. J., Burchell, J. M., Campbell, A. M., Carroll, J. S., Clarke, R. B., Coles, C. E., Cook, G. J. R., Cox, A., Curtin, N. J., Dekker, L. V., dos Santos Silva, I., Duffy, S. W., Easton, D. F., Eccles, D. M., Edwards, D. R., Edwards, J., Evans, D. G., Fenlon, D. F., Flanagan, J. M., Foster, C., Gallagher, W. M., Garcia-Closas, M., Gee, J. M. W., Gescher, A. J., Goh, V., Groves, A. M., Harvey, A. J., Harvie, M., Hennessy, B. T., Hiscox, S., Holen, I., Howell, S. J., Howell, A., Hubbard, G., Hulbert-Williams, N., Hunter, M. S., Jasani, B., Jones, L. J., Key, T. J., Kirwan, C. C., Kong, A., Kunkler, I. H., Langdon, S. P., Leach, M. O., Mann, D. J., Marshall, J. F., Martin, L. A., Martin, S. G., Macdougall, J. E., Miles, D. W., Miller, W. R., Morris, J. R., Moss, S. M., Mullan, P., Natrajan, R., O'Connor, J. P. B., O'Connor, R., Palmieri, C., Pharoah, P. D. P., Rakha, E. A., Reed, E., Robinson, S. P., Sahai, E., Saxton, J. M., Schmid, P., Smalley, M. J., Speirs, V., Stein, R., Stingl, J., Streuli, C. H., Tutt, A. N. J., Velikova, G., Walker, R. A., Watson, C. J., Williams, K. J., Young, L. S. & Thompson, A. M. 2013 In : Breast Cancer Research. 15, 5, R92

    Research output: Contribution to journalArticle

  296. Current and future practices in surgical retraction

    Steele, P. R. C., Curran, J. F. & Mountain, R. E. 2013 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 11, 6, p. 330-337 8 p.

    Research output: Contribution to journalArticle

  297. Current controversies in breast cancer surgery

    Critchley, A. C., Thompson, A. M., Chan, H. Y. & Reed, M. W. 2013 In : Clinical Oncology. 25, 2, p. 101-108 8 p.

    Research output: Contribution to journalArticle

  298. Cutaneous SCC and the RAS controversy

    McHugh, A. T., Purdie, K., Pourreyron, C., Watt, S., Rose, A., Leigh, I., Harwood, C., South, A. & Proby, C. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S66 1 p., 386

    Research output: Contribution to journalMeeting abstract

  299. Cutaneous squamous cell carcinoma carries the highest burden of mutation of any human tumor type and harbors prevalent mutations in CARD11 and CREBBP

    South, A. P., Watt, S. A., Purdie, K. J., Proby, C. M., Harwood, C. A. & Leigh, I. M. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S72 1 p., 427

    Research output: Contribution to journalMeeting abstract

  300. Cutaneous squamous cell carcinoma derived cell lines are more sensitive to the proteasome inhibitor bortezomib than normal skin cells

    Koerver, L., Tura, Z. H., Leigh, I. M., South, A. P. & Saville, M. K. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S183 1 p.

    Research output: Contribution to journalMeeting abstract

  301. Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet (PUVA) sensitivity

    Deeni, Y. Y., Ibbotson, S. H., Woods, J. A., Wolf, C. R. & Smith, G. 2013 In : PLoS ONE. 8, 9, e75494

    Research output: Contribution to journalArticle

  302. DEAD box RNA helicase functions in cancer

    Fuller-Pace, F. V. 2013 In : RNA Biology. 10, 1, p. 121-132 12 p.

    Research output: Contribution to journalArticle

  303. Depletion of MRG-binding protein invokes TIP60 histone acetyltransferase-dependent apoptosis in cutaneous squamous cell carcinoma cells

    Watt, S. A., Arrand, K., Leigh, I. M. & South, A. P. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S71 1 p., 416

    Research output: Contribution to journalMeeting abstract

  304. Detecting and quantifying p53 isoforms at mRNA level in cell lines and tissues

    Khoury, M. P., Marcel, V., Fernandes, K., Diot, A., Lane, D. P. & Bourdon, J-C. 2013 p53 protocols. Deb, S. & Deb, S. P. (eds.). Totowa, N.J.: Humana Press, p. 1-14 14 p. (Methods in Molecular Biology; vol. 962)

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  305. Detecting p53 isoforms at protein level

    Marcel, V., Khoury, M. P., Fernandes, K., Diot, A., Lane, D. P. & Bourdon, J-C. 2013 p53 protocols. Deb, S. & Deb, S. P. (eds.). Totowa, N.J.: Humana Press, p. 15-29 15 p. (Methods in Molecular Biology; vol. 962)

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  306. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells

    Baird, L. & Dinkova-Kostova, A. T. 2013 In : Biochemical and Biophysical Research Communications. 433, 1, p. 58-65 8 p.

    Research output: Contribution to journalArticle

  307. Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

    MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S. 2013 In : Scientific Reports. 3, 1275

    Research output: Contribution to journalArticle

  308. Epidermal HIF-regulating PHD proteins (EGLNs): Response to hypoxia and link to skin pathology

    Weir, L., Robertson, D., Vass, K. & Panteleyev, A. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S115 1 p., 674

    Research output: Contribution to journalMeeting abstract

  309. Expression microarray analysis identifies key processes in the transition from actinic keratosis to cutaneous squamous cell carcinoma

    Lambert, S. R., Mladkova, N., Gulati, A., Hamoudi, R., Purdie, K. J., Cerio, R., Leigh, I. M., Proby, C. M. & Harwood, C. A. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S67 1 p., 393

    Research output: Contribution to journalMeeting abstract

  310. Expression of TP53 isoforms p53β or p53γ enhances chemosensitivity in TP53(null) cell lines

    Silden, E., Hjelle, S. M., Wergeland, L., Sulen, A., Andresen, V., Bourdon, J-C., Micklem, D. R., McCormack, E. & Gjertsen, B. T. 2013 In : PLoS ONE. 8, 2, 11 p., e56276

    Research output: Contribution to journalArticle

  311. Faecal haemoglobin concentration is related to severity of colorectal neoplasia

    Digby, J., Fraser, C. G., Carey, F. A., McDonald, P. J., Strachan, J. A., Diament, R. H., Balsitis, M. & Steele, R. J. C. 2013 In : Journal of Clinical Pathology. 66, 5, p. 415-419 5 p.

    Research output: Contribution to journalArticle

  312. Gauging NOTCH1 activation in cancer using immunohistochemistry

    Leigh, I. M. & 29 others Kluk, M. J., Ashworth, T., Wang, H., Knoechel, B., Mason, E. F., Morgan, E. A., Dorfman, D., Pinkus, G., Weigert, O., Hornick, J. L., Chirieac, L. R., Hirsch, M., Oh, D. J., South, A. P., Pourreyron, C., Cassidy, A. J., DeAngelo, D. J., Weinstock, D. M., Krop, I. E., Dillon, D., Brock, J. E., Lazar, A. J. F., Peto, M., Cho, R. J., Stoeck, A., Haines, B. B., Sathayanrayanan, S., Rodig, S. & Aster, J. C. 2013 In : PLoS ONE. 8, 6, 14 p., e67306

    Research output: Contribution to journalArticle

  313. Immunohistochemical analysis of breast tissue microarray images using contextual classifiers

    McKenna, S. J., Amaral, T., Akbar, S., Jordan, L. & Thompson, A. 2013 In : Journal of Pathology Informatics. 4, Suppl, p. S13 1 p.

    Research output: Contribution to journalArticle

  314. Immunohistochemical assessment of MRG-binding protein and polo-like kinase 1 over-expression in human cutaneous SCC

    Harkins, C., Watt, S. A., Pourreyron, C., Leigh, I. M., Proby, C. M. & South, A. P. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S70 1 p., 414

    Research output: Contribution to journalMeeting abstract

  315. Inhibition of Myostatin Signaling through Notch Activation following Acute Resistance Exercise

    MacKenzie, M. G., Hamilton, D. L., Pepin, M., Patton, A. & Baar, K. 2013 In : PLoS ONE. 8, 7, 68743

    Research output: Contribution to journalArticle

  316. Keratinocyte response to environmental challenge: Cross-effects of hypoxia and calcium

    Weir, L., Robertson, D., Vass, K. & Panteleyev, A. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S115 1 p., 675

    Research output: Contribution to journalMeeting abstract

  317. Longitudinal Analyses of Gut Mucosal Microbiotas in Ulcerative Colitis in Relation to Patient Age and Disease Severity and Duration

    Fite, A., Macfarlane, S., Furrie, E., Bahrami, B., Cummings, J. H., Steinke, D. T. & Macfarlane, G. T. 2013 In : Journal of Clinical Microbiology. 51, 3, p. 849-856 8 p.

    Research output: Contribution to journalArticle

  318. Low-dose phase contrast mammography with conventional x-ray sources

    Olivo, A., Gkoumas, S., Endrizzi, M., Hagen, C. K., Szafraniec, M. B., Diemoz, P. C., Munro, P. R. T., Ignatyev, K., Johnson, B., Horrocks, J. A., Vinnicombe, S. J., Jones, J. L. & Speller, R. D. 2013 In : Medical Physics. 40, 9

    Research output: Contribution to journalArticle

  319. Luminal accumulation of newly synthesized morphine-3-glucuronide in rat liver microsomal vesicles

    Révész, K., Tóth, B., Staines, A. G., Coughtrie, M. W. H., Mandl, J. & Csala, M. 2013 In : BioFactors. 39, 3, p. 271-278 8 p.

    Research output: Contribution to journalArticle

  320. Mammography

    Whelehan, P. 2013 Patient centred care in medical imaging and radiotherapy. Ramlaul, A. & Vosper, M. (eds.). London: Churchill Livingstone Elsevier, p. 205-210 6 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  321. MMP1, 2 and 7 but not 9 or 13 promote cutaneous SCC keratinocyte invasion and migration

    Pourreyron, C., Pautu, V., Simons, M. R., Proby, C. M., Leigh, I. M. & South, A. P. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S156 1 p., 917

    Research output: Contribution to journalMeeting abstract

  322. Multi-modal approach using Raman spectroscopy and optical coherence tomography for the discrimination of colonic adenocarcinoma from normal colon

    Ashok, P. C., Praveen, B. B., Bellini, N., Riches, A., Dholakia, K. & Herrington, C. S. 2013 In : Biomedical Optics Express. 4, 10, p. 2179-2186 8 p.

    Research output: Contribution to journalArticle

  323. Multiparameter DNA content analysis identifies distinct groups in primary breast cancer

    Dayal, J., Sales, M. J., Corver, W. E., Purdie, C. A., Jordan, L. B., Quinlan, P. R., Baker, L., ter Haar, N. T., Pratt, N. R. & Thompson, A. M. 2013 In : British Journal of Cancer. 108, 4, p. 873-880 8 p.

    Research output: Contribution to journalArticle

  324. Mutant p53 in cutaneous squamous cell carcinoma

    Saundh, H., Leigh, I. M., South, A. P. & Saville, M. K. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S70 1 p., 413

    Research output: Contribution to journalMeeting abstract

  325. Optimisation of Wavelength Modulated Raman Spectroscopy: towards high throughput cell screening

    Praveen, B. B., Mazilu, M., Marchington, R. F., Dholakia, K., Herrington, C. S. & Riches, A. 2013 In : PLoS ONE. 8, 6

    Research output: Contribution to journalArticle

  326. p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

    Groves, M. J., Johnson, C. E., James, J., Prescott, A. R., Cunningham, J., Haydock, S., Pepper, C., Fegan, C., Pirrie, L., Westwood, N. J., Coates, P. J., Ganley, I. G. & Tauro, S. 2013 In : British Journal of Cancer. 109, October, p. 2432=2444 13 p.

    Research output: Contribution to journalArticle

  327. Photopatch testing: recommendations for a European photopatch test baseline series

    Gonçalo, M., Ferguson, J., Bonevalle, A., Bruynzeel, D. P., Giménez-Arnau, A., Goossens, A., Kerr, A., Lecha, M., Neumann, N., Niklasson, B., Pigatto, P., Rhodes, L. E., Rustemeyer, T., Sarkany, R., Thomas, P. & Wilkinson, M. 2013 In : Contact Dermatitis. 68, 4, p. 239-243 5 p.

    Research output: Contribution to journalArticle

  328. Primary breast cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up

    Senkus, E., Kyriakides, S., Penault-Llorca, F., Poortmans, P., Thompson, A., Zackrisson, S. & Cardoso, F. 2013 In : Annals of Oncology. 24, SUPPL.6, p. vi7-vi23 17 p.

    Research output: Contribution to journalArticle

  329. Progesterone receptor expression is an independent prognostic variable in early breast cancer: a population-based study

    Purdie, C. A., Quinlan, P., Jordan, L. B., Ashfield, A., Ogston, S., Dewar, J. A. & Thompson, A. M. 2013 In : British Journal of Cancer.

    Research output: Contribution to journalArticle

  330. Regulation of the cardiac Na(+) pump by palmitoylation of its catalytic and regulatory subunits

    Howie, J., Tulloch, L. B., Shattock, M. J. & Fuller, W. 2013 In : Biochemical Society Transactions. 41, 1, p. 95-100 6 p.

    Research output: Contribution to journalArticle

  331. RNA trans-splicing molecules for targeted suicide gene delivery into cancer cells

    Gruber, C., Koller, U., Hainzl, S., Murauer, E. M., Huettner, C., South, A. P., Hintner, H. & Bauer, J. W. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S64 1 p., 375

    Research output: Contribution to journalMeeting abstract

  332. RNAi depletion of PRSS21 in cutaneous squamous cell carcinoma keratinocytes induces maspin dependent apoptosis

    Robinson, K. S., Watt, S. A., Leigh, I. M. & South, A. P. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S72 1 p., 423

    Research output: Contribution to journalMeeting abstract

  333. RXRα Inhibits the NRF2-ARE Signaling Pathway through a Direct Interaction with the Neh7 Domain of NRF2

    Wang, H., Liu, K., Geng, M., Gao, P., Wu, X., Hai, Y., Li, Y., Li, Y., Luo, L., Hayes, J. D., Wang, X. J. & Tang, X. 2013 In : Cancer Research. 73, 10, p. 3097-3108 12 p.

    Research output: Contribution to journalArticle

  334. Socioeconomic variation and prostate specific antigen testing in the community: a United kingdom based population study

    Morgan, R. M., Steele, R. J. C., Nabi, G. & McCowan, C. 2013 In : Journal of Urology. 190, 4, p. 1207-1212 6 p.

    Research output: Contribution to journalArticle

  335. Subclinical and asymptomatic parathyroid disease: implications of emerging data

    Macfarlane, D. P., Yu, N. & Leese, G. P. 2013 In : The Lancet Diabetes and Endocrinology. 1, 4, p. 329-340 12 p.

    Research output: Contribution to journalArticle

  336. Technologic Developments in the Field of Photonics for the Detection of Urinary Bladder Cancer

    Palmer, S. G., Sokolovski, S. G., Rafailov, E. & Nabi, G. 2013 In : Clinical Genitourinary Cancer. 11, 4, p. 390-396 7 p.

    Research output: Contribution to journalArticle

  337. The CD11b-integrin (ITGAM) and systemic lupus erythematosus

    Fagerholm, S. C., Macpherson, M., James, M. J., Sevier-Guy, C. & Lau, C. S. 2013 In : Lupus. 22, 7, p. 657-663 7 p.

    Research output: Contribution to journalArticle

  338. The development of cutaneous squamous lesions in patients treated with vemurafenib: a possible role for human papillomavirus in addition to activated RAS

    Purdie, K., South, A., Sommerlad, M., Leigh, I., Proby, C. & Harwood, C. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S61 1 p., 357

    Research output: Contribution to journalMeeting abstract

  339. The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells

    Plitzko, B., Ott, G., Reichmann, D., Henderson, C. J., Wolf, C. R., Mendel, R., Bittner, F., Clement, B. & Havemeyer, A. 2013 In : Journal of Biological Chemistry. 288, 28, p. 20228-20237 10 p.

    Research output: Contribution to journalArticle

  340. The manufacture and assessment of tissue microarrays: suggestions and criteria for analysis, with breast cancer as an example

    Pinder, S. E., Brown, J. P., Gillett, C., Purdie, C., Speirs, V., Thompson, A. M., Shaaban, A. M. & NCRI Breast Clinical Studies Grp 2013 In : Journal of Clinical Pathology. 66, 3, p. 169-177 9 p.

    Research output: Contribution to journalArticle

  341. Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1–PP2A protein complex

    Krauss, S., Griesche, N., Jastrzebska, E., Chen, C., Rutschow, D., Achmuller, C., Dorn, S., Boesch, S. M., Lalowski, M., Wanker, E., Schneider, R. & Schweiger, S. 2013 In : Nature Communications. 4, 1511

    Research output: Contribution to journalArticle

  342. Transperitoneal laparoscopic renal denervation for the management of loin pain haematuria syndrome

    Kadi, N., Mains, E., Townell, N. & Nabi, G. 2013 In : Minimally Invasive Therapy and Allied Technologies. 22, 6, p. 346-351 6 p.

    Research output: Contribution to journalArticle

  343. Transplantation of hair follicle dermal cells as a therapeutic approach for recessive dystrophic epidermolysis bullosa

    Gledhill, K., Bruckner-Tuderman, L., Christiano, A., South, A. P. & Jahoda, C. A. 2013 In : Journal of Investigative Dermatology. 133, 5, p. 1429 1 p., P226

    Research output: Contribution to journalMeeting abstract

  344. Type VII collagen regulates front-to-rear polarity in primary cutaneous squamous cell carcinoma keratinocytes

    Dayal, J. H., Pourreyron, C., Watt, S. A., Leigh, I. M. & South, A. P. 2013 In : Journal of Investigative Dermatology. 133, S1, p. S157 1 p., 921

    Research output: Contribution to journalMeeting abstract

  345. Understanding eating behaviour and lifestyle issues on women's health: implications for obesity development and prevention

    Anderson, A. S. & Craigie, A. M. 2013 Obesity: a ticking time bomb for reproductive health. Mahmood, T. & Arulkumaran, S. (eds.). London: Elsevier, p. 597-606 10 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  346. Use of the high dependency unit, increased consultant involvement and reduction in adverse events in patients who die after colorectal cancer surgery

    Young, J. A., Waugh, L., Mcphillips, G., Steele, R. J. C. & Thompson, A. M. 2013 In : Colorectal Disease. 15, 7, p. 824-829 6 p.

    Research output: Contribution to journalArticle

  347. Utility of stages of change construct in the planning of physical activity interventions among playgroup mothers

    Jones, C., Jancey, J., Howat, P., Dhaliwal, S., Burns, S., McManus, A., Hills, A. P. & Anderson, A. S. 2013 In : BMC Research Notes. 6, 1, 300

    Research output: Contribution to journalArticle

  348. What should it take to describe a substance or product as 'sperm-safe'

    Mortimer, D., Barratt, C. L. R., Björndahl, L., de Jager, C., Jequier, A. M. & Muller, C. H. 2013 In : Human Reproduction Update. 19, SUPPL1, p. i1-i45 45 p.

    Research output: Contribution to journalArticle

  349. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8 T cells

    Finlay, D. K., Rosenzweig, E., Sinclair, L. V., Feijoo-Carnero, C., Hukelmann, J. L., Rolf, J., Panteleyev, A. A., Okkenhaug, K. & Cantrell, D. A. 17 Dec 2012 In : Journal of Experimental Medicine. 209, 13, p. 2441-2453 13 p.

    Research output: Contribution to journalArticle

  350. A novel wafer-scale CMOS APS X-ray detector for breast cancer diagnosis using X-ray diffraction studies

    Konstantinidis, A., Zheng, Y., Philip, D., Vinnicombe, S. & Speller, R. 7 Dec 2012 In : Journal of Instrumentation. 7, 12, 5 p.

    Research output: Contribution to journalArticle

  351. Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility

    McGrath, J. A., Stone, K. L., Begum, R., Simpson, M. A., Dopping-Hepenstal, P. J., Liu, L., McMillan, J. R., South, A. P., Pourreyron, C., McLean, W. H. I., Martinez, A. E., Mellerio, J. E. & Parsons, M. 7 Dec 2012 In : American Journal of Human Genetics. 91, 6, p. 1115-1121 7 p.

    Research output: Contribution to journalArticle

  352. Selective sampling using confocal Raman spectroscopy provides enhanced specificity for urinary bladder cancer diagnosis

    Barman, I., Dingari, N. C., Singh, G. P., Kumar, R., Lang, S. & Nabi, G. 1 Dec 2012 In : Analytical and Bioanalytical Chemistry. 404, 10, p. 3091-3099 9 p.

    Research output: Contribution to journalArticle

  353. 2-APB-potentiated channels amplify CatSper-induced Ca signals in human sperm

    Lefièvre, L., Nash, K., Mansell, S., Costello, S., Punt, E., Correia, J., Morris, J., Kirkman-Brown, J., Wilson, S. M., Barratt, C. L. R. & Publicover, S. Dec 2012 In : Biochemical Journal. 448, 2, p. 189-200 12 p.

    Research output: Contribution to journalArticle

  354. The indirect antioxidant sulforaphane protects against thiopurine-mediated photooxidative stress

    Benedict, A. L., Knatko, E. V. & Dinkova-Kostova, A. T. Dec 2012 In : Carcinogenesis. 33, 12, p. 2457-2466 10 p.

    Research output: Contribution to journalArticle

  355. Tissue factor pathway inhibitor 2 (TFPI2) is commonly methylated in multiple myeloma

    Hatzimichael, E., Dasoula, A., Kounnis, V., Katsenos, A., Crook, T. & Briasoulis, E. 16 Nov 2012 In : Blood. 120, 21, 1 p., 4617

    Research output: Contribution to journalMeeting abstract

  356. Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β

    Lu, Q., Lu, Z., Liu, Q., Guo, L., Ren, H., Fu, J., Jiang, Q., Clarke, P. R. & Zhang, C. Nov 2012 In : Cell Research. 22, p. 1562-1575 14 p.

    Research output: Contribution to journalArticle

  357. Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer

    Smith, G., Ng, M. T. H., Shepherd, L., Herrington, C. S., Gourley, C., Ferguson, M. & Wolf, C. R. 9 Oct 2012 In : British Journal of Cancer. 107, 8, p. 1327-1336 10 p.

    Research output: Contribution to journalArticle

  358. Chronic preoperative pain and psychological robustness predict acute postoperative pain outcomes after surgery for breast cancer

    Bruce, J., Thornton, A. J., Scott, N. W., Marfizo, S., Powell, R., Johnston, M., Wells, M., Heys, S. D. & Thompson, A. M. 4 Sep 2012 In : British Journal of Cancer. 107, p. 937-946 10 p.

    Research output: Contribution to journalArticle

  359. European guidelines for quality assurance in colorectal cancer screening and diagnosis: first edition- professional requirements and training

    Steele, R. J. C., Rey, J-F. & Lambert, R. Sep 2012 In : Endoscopy. 44, S 03, p. SE106-SE115 10 p.

    Research output: Contribution to journalArticle

  360. European guidelines for quality assurance in colorectal cancer screening and diagnosis: first edition-management of lesions detected in colorectal cancer screening

    Steele, R. J. C., Pox, C., Kuipers, E. J., Minoli, G. & Lambert, R. Sep 2012 In : Endoscopy. 44 , S 03, p. SE140-SE150 11 p.

    Research output: Contribution to journalArticle

  361. Exome level sequencing identifies candidate genes mutated in cutaneous squamous cell carcinoma progression

    South, A. P., Purdie, K. J., Watt, S. A., Harwood, C. A., Proby, C. & Leigh, I. M. Sep 2012 In : Journal of Investigative Dermatology. 132, p. S37-S37 1 p.

    Research output: Contribution to journalMeeting abstract

  362. Expression of activated NOTCH1 induces terminal differentiation in squamous cell carcinoma keratinocytes

    Robinson, K. S., Purdie, K. J., Cho, R. J., Aster, J. C., Leigh, I. M. & South, A. P. Sep 2012 In : Journal of Investigative Dermatology. 132, p. S40-S40 1 p.

    Research output: Contribution to journalMeeting abstract

  363. Functional analysis of a genetic variant of ITGAM (CD11b/Mac-1) associated with systemic lupus erythematosus

    Sevier-Guy, C., MacPherson, M. & Fagerholm, S. Sep 2012 In : Immunology. 137, S1, p. 579-579 1 p.

    Research output: Contribution to journalMeeting abstract

  364. Mps1 promotes rapid centromere accumulation of Aurora B

    van der Waal, M. S., Saurin, A. T., Vromans, M. J. M., Vleugel, M., Wurzenberger, C., Gerlich, D. W., Medema, R. H., Kops, G. J. P. L. & Lens, S. M. A. Sep 2012 In : EMBO Reports. 13, 9, p. 847-854 8 p.

    Research output: Contribution to journalArticle

  365. Phaeochromocytomas associated with PTEN mutation demonstarate tissue specificity in the anti-tumour effect of mTOR inhibition

    Taggart, C. & Fleming, S. Sep 2012 In : Journal of Pathology. 228, Suppl. 1, p. S37-S37 1 p.

    Research output: Contribution to journalMeeting abstract

  366. Diabetes, Metformin, and Breast Cancer: Lilac Time?

    Goodwin, P. J., Thompson, A. M. & Stambolic, V. 10 Aug 2012 In : Journal of Clinical Oncology. 30, 23, p. 2812-2814 3 p.

    Research output: Contribution to journalEditorial

  367. Corrigendum. Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor negative breast cancer (vol 106, pg 1453, 2012)

    Ohotski, J., Long, J. S., Orange, C., Elsberger, B., Mallon, E., Doughty, J., Pyne, S., Pyne, N. J. & Edwards, J. 7 Aug 2012 In : British Journal of Cancer. 107, 4, p. 756-756 1 p.

    Research output: Contribution to journalArticle

  368. Influenza A viruses control expression of proviral human p53 isoforms p53β and Delta133p53α

    Terrier, O., Marcel, V., Cartet, G., Lane, D. P., Lina, B., Rosa-Calatrava, M. & Bourdon, J-C. Aug 2012 In : Journal of Virology. 86, 16, p. 8452-8460 9 p.

    Research output: Contribution to journalArticle

  369. Risk factors for actinic keratosis in eight European centres: a case-control study

    Traianou, A. , Ulrich, M. , Apalla, Z. , De Vries, E. , Bakirtzi, K. , Kalabalikis, D. , Ferrandiz, L. , Ruiz-de-Casas, A. , Moreno-Ramirez, D. , Sotiriadis, D. , Ioannides, D. , Aquilina, S. , Apap, C. , Micallef, R. , Scerri, L. , Pitkanen, S. , Saksela, O. , Altsitsiadis, E. , Hinrichs, B. , Magnoni, C. & 7 others Fiorentini, C., Majewski, S., Ranki, A., Proby, C. M., Stockfleth, E., Trakatelli, M. & EPIDERM Grp Aug 2012 In : British Journal of Dermatology. 167, p. 36-42 7 p.

    Research output: Contribution to journalArticle

  370. Spironolactone and the risk of breast cancer: a cohort study

    Mackenzie, I. S., MacDonald, T. M., Thompson, A. M., Morant, S. & Wei, L. Aug 2012 In : Pharmacoepidemiology and Drug Safety. 21, Supplement s3, p. 258-258 1 p., 550

    Research output: Contribution to journalMeeting abstract

  371. ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways

    Robertson, E. D., Weir, L., Romanowska, M., Leigh, I. M. & Panteleyev, A. A. 15 Jul 2012 In : Journal of Cell Science. 125, 14, p. 3320-3332 13 p.

    Research output: Contribution to journalArticle

  372. Methylation of the calcium channel regulatory subunit alpha 2 delta-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas

    Palmieri, C., Rudraraju, B., Monteverde, M., Lattanzio, L., Gojis, O., Brizio, R., Garrone, O., Merlano, M., Syed, N., Lo Nigro, C. & Crook, T. 10 Jul 2012 In : British Journal of Cancer. 107, 2, p. 375-381 7 p.

    Research output: Contribution to journalArticle

  373. Diminished toxicity of C-1748, 4-methyl-9-hydroxyethylamino-1-nitroacridine, compared with its demethyl analog, C-857, corresponds to its resistance to metabolism in HepG2 cells

    Wisniewska, A., Niemira, M., Jagiello, K., Potega, A., Swist, M., Henderson, C., Skwarska, A., Augustin, E., Konopa, J. & Mazerska, Z. 1 Jul 2012 In : Biochemical Pharmacology. 84, 1, p. 30-42 13 p.

    Research output: Contribution to journalArticle

  374. Fluorescence suppression using wavelength modulated Raman spectroscopy in fiber-probe-based tissue analysis

    Praveen, B. B., Ashok, P. C., Mazilu, M., Riches, A., Herrington, S. & Dholakia, K. Jul 2012 In : Journal of Biomedical Optics. 17, 7, p. - 6 p., 077006

    Research output: Contribution to journalArticle

  375. Impact of the revised (2008) EORTC/MSG definitions for invasive fungal disease on the rates of diagnosis of invasive aspergillosis

    Tsitsikas, D. A., Morin, A., Araf, S., Murtagh, B., Johnson, G., Vinnicombe, S., Ellis, S., Suaris, T., Wilks, M., Doffman, S. & Agrawal, S. G. Jul 2012 In : Medical Mycology : Official Publication of the International Society for Human and Animal Mycology. 50, 5, p. 538-42 5 p.

    Research output: Contribution to journalArticle

  376. Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling

    Sturrock, M., Terry, A. J., Xirodimas, D. P., Thompson, A. M. & Chaplain, M. A. J. Jul 2012 In : Bulletin of Mathematical Biology. 74, 7, p. 1531-1579 49 p.

    Research output: Contribution to journalArticle

  377. The DSPII splice variant is crucial for desmosome-mediated adhesion in HaCaT keratinocytes

    Cabral, R. M., Tattersall, D., Patel, V., McPhail, G. D., Hatzimasoura, E., Abrams, D. J., South, A. P. & Kelsell, D. P. 15 Jun 2012 In : Journal of Cell Science. 125, 12, p. 2853-2861 9 p.

    Research output: Contribution to journalArticle

  378. Toward standardizing and reporting colorectal cancer screening indicators on an international level: the international colorectal cancer screening network

    Benson, V. S., Atkin, W. S., Green, J., Nadel, M. R., Patnick, J., Smith, R. A., Villain, P., International Colorectal Cancer Screening Network & Steele, R. J. C. 15 Jun 2012 In : International Journal of Cancer. 130, 12, p. 2961-73 13 p.

    Research output: Contribution to journalArticle

  379. Chloride channels join the sperm 'channelome'

    Publicover, S. J. & Barratt, C. L. R. Jun 2012 In : Journal of Physiology. 590, 11, p. 2553-2554 2 p.

    Research output: Contribution to journalArticle

  380. Invasive breast cancer: relationship between shear-wave elastographic findings and histologic prognostic factors

    Evans, A., Whelehan, P., Thomson, K., McLean, D., Brauer, K., Purdie, C., Baker, L., Jordan, L., Rauchhaus, P. & Thompson, A. Jun 2012 In : Radiology. 263, 3, p. 673-677 5 p.

    Research output: Contribution to journalArticle

  381. A Redox-Regulated SUMO/Acetylation Switch of HIPK2 Controls the Survival Threshold to Oxidative Stress

    de la Vega, L., Grishina, I., Moreno, R., Krüger, M., Braun, T. & Schmitz, M. L. 25 May 2012 In : Molecular Cell. 46, 4, p. 472-483 12 p.

    Research output: Contribution to journalArticle

  382. Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents

    Zheng, S., Laxmi, Y. R. S., David, E., Dinkova-Kostova, A. T., Shiavoni, K. H., Ren, Y., Zheng, Y., Trevino, I., Bumeister, R., Ojima, I., Wigley, W. C., Bliska, J. B., Mierke, D. F. & Honda, T. 24 May 2012 In : Journal of Medicinal Chemistry. 55, 10, p. 4837-4846 10 p.

    Research output: Contribution to journalArticle

  383. Axillary lymph node core biopsy for breast cancer metastases - How many needle passes are enough?

    Macaskill, E. J., Purdie, C. A., Jordan, L. B., Mclean, D., Whelehan, P., Brown, D. C. & Evans, A. May 2012 In : Clinical Radiology. 67, 5, p. 417-419 3 p.

    Research output: Contribution to journalArticle

  384. Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues

    Matthews, S. A., Lek, H. S., Morrison, V. L., Mackenzie, M. G., Zarrouk, M., Cantrell, D. & Fagerholm, S. C. May 2012 In : European Journal of Immunology. 42, 5, p. 1316-1326 11 p.

    Research output: Contribution to journalArticle

  385. The p53 isoforms are differentially modified by Mdm2

    Camus, S., Menendez, S., Fernandes, K., Kua, N., Liu, G., Xirodimas, D. P., Lane, D. P. & Bourdon, J-C. 15 Apr 2012 In : Cell Cycle. 11, 8, p. 1646-1655 10 p.

    Research output: Contribution to journalArticle

  386. Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer

    Ohotski, J., Long, J. S., Orange, C., Elsberger, B., Mallon, E., Doughty, J., Pyne, S., Pyne, N. J. & Edwards, J. 10 Apr 2012 In : British Journal of Cancer. 106, 8, p. 1453-1459 7 p.

    Research output: Contribution to journalArticle

  387. Regulation of the cardiac sodium pump

    Fuller, W., Tulloch, L. B., Howie, J., Wypijewski, K. J., Shattock, M. J. & Calaghan, S. C. Apr 2012 In : Cellular and Molecular Life Sciences. 70, 8, p. 1357-1380 24 p.

    Research output: Contribution to journalArticle

  388. Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment

    Elsberger, B., Paravasthu, D. M., Tovey, S. M. & Edwards, J. Feb 2012 In : Journal of Cancer Research and Clinical Oncology. 138, 2, p. 327-332 6 p.

    Research output: Contribution to journalArticle

  389. Comparison of Visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer

    Mohammed, Z. M. A., McMillan, D. C., Elsberger, B., Going, J. J., Orange, C., Mallon, E., Doughty, J. C. & Edwards, J. 17 Jan 2012 In : British Journal of Cancer. 106, 2, p. 383-388 6 p.

    Research output: Contribution to journalArticle

  390. High frequency of complex TP53 mutations in CNS metastases from breast cancer

    Lo Nigro, C., Vivenza, D., Monteverde, M., Lattanzio, L., Gojis, O., Garrone, O., Comino, A., Merlano, M., Quinlan, P. R., Syed, N., Purdie, C. A., Thompson, A., Palmieri, C. & Crook, T. 17 Jan 2012 In : British Journal of Cancer. 106, 2, p. 397-404 8 p.

    Research output: Contribution to journalArticle

  391. MAGE-A antigens as targets in tumour therapy

    Meek, D. W. & Marcar, L. 1 Jan 2012 In : Cancer Letters.

    Research output: Contribution to journalArticle

  392. Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in cancer

    Coley, H. M., Hatzimichael, E., Blagden, S., McNeish, I., Thompson, A., Crook, T. & Syed, N. Jan 2012 In : Oncotarget. 3, 1, p. 78-83 6 p.

    Research output: Contribution to journalArticle

  393. A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences

    Shaaban, A. M. , Ball, G. R. , Brannan, R. A. , Cserni, G. , Di Benedetto, A. , Dent, J. , Fulford, L. , Honarpisheh, H. , Jordan, L. , Jones, J. L. , Kanthan, R. , Maraqa, L. , Litwiniuk, M. , Mottolese, M. , Pollock, S. , Provenzano, E. , Quinlan, P. R. , Reall, G. , Shousha, S. , Stephens, M. & 4 others Verghese, E. T., Walker, R. A., Hanby, A. M. & Speirs, V. 2012 In : Breast Cancer Research and Treatment. 133, 3, p. 949-958 10 p.

    Research output: Contribution to journalArticle

  394. A comparison of the accuracy of film-screen mammography, full-field digital mammography, and digital breast tomosynthesis

    Michell, M. J., Iqbal, A., Wasan, R. K., Evans, D. R., Peacock, C., Lawinski, C. P., Douiri, A., Wilson, R. & Whelehan, P. 2012 In : Clinical Radiology. 67, 10, p. 976-981 6 p.

    Research output: Contribution to journalArticle

  395. A European multicentre photopatch test study: The European Multicentre Photopatch Test Study (EMCPPTS) taskforce

    Kerr, A. C. , Ferguson, J. , Haylett, A. K. , Rhodes, L. E. , Adamski, H. , Alomar, A. , Serra, E. , Antoniou, C. , Aubin, F. , Vigan, M. , Biedermann, T. , Fischer, J. , Bourrain, J-L. , Bruynzeel, D. , Rustemeyer, T. , Carrascosa, J. M. , Chowdhury, M. M. U. , de la Cuadra, J. , Foti, C. , Gardeazabal, J. & 22 others Gawkrodger, D. J., Gimenez-Arnau, A., Goncalo, M., Goossens, A., Ibbotson, S. H., Dawe, R. S., Lecha, M., Marguery, M-C., Neumann, N. J., Niklasson, B., Peyron, J-L., Pigatto, P., Spiewak, R., Stone, N., Tanew, A., Thomas, P., Bonnevalle, A., Wilkinson, S. M., Wolf, P., Gruber-Wackernagel, A., Wulf, H. C. & European Multictr Photopatch Test 2012 In : British Journal of Dermatology. 166, 5, p. 1002-1009 8 p.

    Research output: Contribution to journalArticle

  396. A rapid 3D model of abdominal organs for transcostal HIFU therapy

    Cao, R., Gao, J., Corner, G., Nabi, G. & Huang, Z. 2012

    Research output: Contribution to conferenceAbstract

  397. An analysis and hypothesis generation platform for heterogeneous cancer databases

    Quinlan, P. R., Thompson, A. & Reed, C. 2012 Computational Models of Argument: Proceedings of COMMA 2012. Verheij, B., Szeider, S. & Woltran, S. (eds.). Amsterdam: IOS Press, p. 59-70 12 p. (Frontiers in artificial intelligence and applications; vol. 245)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  398. Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics

    Abdullah, A., Kitteringham, N. R., Jenkins, R. E., Goldring, C., Higgins, L., Yamamoto, M., Hayes, J. & Park, B. K. 2012 In : Pharmacological Reports. 64, 3, p. 680-697 18 p.

    Research output: Contribution to journalArticle

  399. Assessing physicians' preferences on skin cancer treatment in Europe

    Ferrandiz, L., Ruiz-de-Casas, A., Trakatelli, M., de Vries, E., Ulrich, M., Aquilina, S., Saksela, O., Majewski, S., Ranki, A., Proby, C., Magnoni, C., Pitkanen, S., Kalokasidis, K., Siskou, S., Hinrichs, B., Altsitsiadis, E., Stockfleth, E., Moreno-Ramirez, D. & EPIDERM Grp 2012 In : British Journal of Dermatology. 167, S2, p. 29-35 7 p.

    Research output: Contribution to journalArticle

  400. Autophagy inhibitor chloroquine enhanced the cell death inducing effect of the flavonoid luteolin in metastatic squamous cell carcinoma cells

    Verschooten, L., Barrette, K., Van Kelst, S., Romero, N. R., Proby, C., De Vos, R., Agostinis, P. & Garmyn, M. 2012 In : PLoS ONE. 7, 10, p. - 11 p., e48264

    Research output: Contribution to journalArticle

  401. Beyond detection: biological physics informing progression and treatment of cancer PREFACE

    Newman, T. J. & Thompson, A. M. 2012 In : Physical Biology. 9, 6, p. - 2 p., 060301

    Research output: Contribution to journalEditorial

  402. Biomarker discordance: prospective and retrospective evidence that biopsy of recurrent disease is of clinical utility

    Moussa, O., Purdie, C., Vinnicombe, S. & Thompson, A. M. 2012 In : Cancer Biomarkers. 12, 6, p. 231-239 9 p.

    Research output: Contribution to journalArticle

  403. Characterisation of skin autofluorescence to establish its role in distinguishing between normal and diseased skin

    Woods, J., Robinson, K., Moseley, H., Gardner, J. & Ibbotson, S. 2012 In : Lasers in Medical Science. 27, 5, p. 870

    Research output: Contribution to journalMeeting abstract

  404. Characterizing breast phenotype with a novel measure of fibroglandular structure

    Hipwell, J. H., Griffin, L. D., Whelehan, P. J., Song, W., Zhang, X., Lesniak, J. M., Vinnicombe, S., Evans, A., Berg, J. & Hawkes, D. J. 2012 Breast Imaging: 11th International Workshop, IWDM 2012, Philadelphia, PA, USA, July 8-11, 2012. Proceedings. Maidment, A. D. A., Bakic, P. R. & Gavenonis, S. (eds.). Berlin: Springer , p. 181-188 8 p. (Lecture notes in computer science; vol. 7361)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  405. Comparison of breast doses for digital tomosynthesis estimated from patient exposures and using PMMA breast phantoms

    Dance, D. R., Strudley, C. J., Young, K. C., Oduko, J. M., Whelehan, P. & Lindsay Mungutroy, E. H. 2012 Breast Imaging: 11th International Workshop, IWDM 2012, Philadelphia, PA, USA, July 8-11, 2012. Proceedings. Maidment, A. D. A., Bakic, P. R. & Gavenonis, S. (eds.). Berlin: Springer , p. 316-321 6 p. (Lecture notes in computer science; vol. 7361)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  406. Crosstalk between p53 and TGF-β Signalling

    Elston, R. & Inman, G. J. 2012 In : Journal of Signal Transduction. 2012, p. 294097

    Research output: Contribution to journalArticle

  407. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

    Muller, P., Ruckova, E., Halada, P., Coates, P. J., Hrstka, R., Lane, D. P. & Vojtesek, B. 2012 In : Oncogene.

    Research output: Contribution to journalArticle

  408. DEAD-box RNA helicases as transcription cofactors

    Fuller-Pace, F. V. & Nicol, S. M. 2012 RNA helicases. Jankowsky, E. (ed.). Academic Press, p. 347-367 21 p. (Methods in Enzymology; vol. 5111)

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  409. Development of lentiviral gene therapy for type VII collagen deficient epidermolysis bullosa

    Georgiadis, C., Thrasher, A., South, A. P., McGrath, J., Qasim, W. & Di, W. 2012 In : Journal of Investigative Dermatology. 132, S2, p. S96 1 p., 546

    Research output: Contribution to journalMeeting abstract

  410. Differentiating benign from malignant solid breast masses: value of shear wave elastography according to lesion stiffness combined with greyscale ultrasound according to BI-RADS classification

    Evans, A., Whelehan, P., Thomson, K., Brauer, K., Jordan, L., Purdie, C., McLean, D., Baker, L., Vinnicombe, S. & Thompson, A. 2012 In : British Journal of Cancer. 107, 2, p. 224-9 6 p.

    Research output: Contribution to journalArticle

  411. Dose-response relationship toxicity of CAR activators in mice

    Elcombe, C. 2012 In : Toxicology Letters. 211, p. S22-S22 1 p.

    Research output: Contribution to journalMeeting abstract

  412. Dual-specificity MAP kinase phosphatases (MKPs): Shaping the outcome of MAP kinase signalling

    Caunt, C. J. & Keyse, S. M. 2012 In : FEBS Journal.

    Research output: Contribution to journalArticle

  413. Embryonic stem cells: a signalling perspective

    Stavridis, M. P. 2012 Mitochondrial DNA, mitochondria, disease and stem cells. St. John, J. (ed.). Humana Press, p. 49-68 (Stem cell biology and regenerative medicine)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  414. Epigenetic silencing of Arginino-Succinate Synthase (Ass1) defines Arginine Depletion Therapy as a novel treatment strategy for breast cancer

    Cavicchioli, F., Shia, A., O'Leary, K., Haley, V., Palmieri, C., Syed, N., Crook, T., Thompson, A. M., Lo Nigro, C. & Schmid, P. 2012 In : Annals of Oncology. 23, S9, p. 532-533 2 p., 1660P

    Research output: Contribution to journalMeeting abstract

  415. ERβ1 represses basal-like breast cancer epithelial to mesenchymal transition by destabilizing EGFR

    Thomas, C., Rajapaksa, G., Nikolos, F., Hao, R., Katchy, A., McCollum, C. W., Bondesson, M., Quinlan, P., Thompson, A., Krishnamurthy, S., Esteva, F. J. & Gustafsson, J-A. 2012 In : Breast Cancer Research. 14, 6, 15 p., R148

    Research output: Contribution to journalArticle

  416. Exposure to benzo[a]pyrene of hepatic cytochrome P450 reductase null (HRN) and P450 reductase conditional null (RCN) mice: detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-postlabelling

    Arlt, V. M., Poirier, M. C., Sykes, S. E., John, K., Moserova, M., Stiborova, M., Wolf, C. R., Henderson, C. J. & Phillips, D. H. 2012 In : Toxicology Letters. 213, 2, p. 160-166 7 p.

    Research output: Contribution to journalArticle

  417. Fibroblast-derived dermal matrix drives development of aggressive cutaneous squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa

    Ng, Y-Z., Pourreyron, C., Salas-Alanis, J. C., Dayal, J. H. S., Cepeda-Valdes, R., Yan, W., Wright, S., Chen, M., Fine, J-D., Hogg, F. J., McGrath, J. A., Murrell, D. F., Leigh, I. M., Lane, E. B. & South, A. P. 2012 In : Cancer Research. 72, 14, p. 3522-3534 13 p.

    Research output: Contribution to journalArticle

  418. Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

    Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218 7 p.

    Research output: Contribution to journalArticle

  419. Giant pendulous fibroma of the breast associated with a locally advanced carcinoma of the breast

    Mullen, R., Reiss, M. M., Fleming, D., Evans, A. & Purdie, C. A. 2012 In : Breast Journal. 18, 6, p. 602-603 2 p.

    Research output: Contribution to journalArticle

  420. Glucosinolates and isothiocyanates in health and disease

    Dinkova-Kostova, A. T. & Kostov, R. V. 2012 In : Trends in Molecular Medicine. 18, 6, p. 337-347 11 p.

    Research output: Contribution to journalArticle

  421. Heterogeneity of p53-pathway Protein Expression in Chemosensitive Chronic Lymphocytic Leukemia: A Pilot Study

    Groves, M. J., Maccallum, S. F., Boylan, M. T., Haydock, S., Cunningham, J., Gelly, K., Gowans, D., Kerr, R., Coates, P. J. & Tauro, S. 2012 In : Journal of Cancer. 3, p. 354-361 8 p.

    Research output: Contribution to journalArticle

  422. Highly potent activation of Nrf2 by topical tricyclic bis(cyano enone): Implications for protection against UV radiation during thiopurine therapy

    Kalra, S., Knatko, E. V., Zhang, Y., Honda, T., Yamamoto, M. & Dinkova-Kostova, A. T. 2012 In : Cancer Prevention Research. 5, 7, p. 973-981 9 p.

    Research output: Contribution to journalArticle

  423. Human papillomavirus infection and its association with neoplasia: from molecular biology to prevention and treatment

    Oparka, R. & Herrington, C. S. 2012 Small DNA tumour viruses. Gaston, K. (ed.). Wymondham: Caister Academic Press, p. 1-18 18 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  424. Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcome

    King, S. I., Purdie, C. A., Bray, S. E., Quinlan, P. R., Jordan, L. B., Thompson, A. M. & Meek, D. W. 2012 In : Breast Cancer Research. 14, 2, p. - 11 p., R40

    Research output: Contribution to journalArticle

  425. Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study

    de Vries, E. , Trakatelli, M. , Kalabalikis, D. , Ferrandiz, L. , Ruiz-de-Casas, A. , Moreno-Ramirez, D. , Sotiriadis, D. , Ioannides, D. , Aquilina, S. , Apap, C. , Micallef, R. , Scerri, L. , Ulrich, M. , Pitkanen, S. , Saksela, O. , Altsitsiadis, E. , Hinrichs, B. , Magnoni, C. , Fiorentini, C. , Majewski, S. & 4 others Ranki, A., Stockfleth, E., Proby, C. & EPIDERM Grp 2012 In : British Journal of Dermatology. 167, p. 1-13 13 p.

    Research output: Contribution to journalArticle

  426. Liver hypertrophy: a review of adaptive (adverse and non-adverse) changes-conclusions from the 3rd International ESTP Expert Workshop

    Hall, A. P., Elcombe, C. R., Foster, J. R., Harada, T., Kaufmann, W., Knippel, A., Kuettler, K., Malarkey, D. E., Maronpot, R. R., Nishikawa, A., Nolte, T., Schulte, A., Strauss, V. & York, M. J. 2012 In : Toxicologic Pathology. 40, 7, p. 971-994 24 p.

    Research output: Contribution to journalArticle

  427. Low Dose Responses of Bone Marrow to X-Rays In Vivo

    Zyuzikov, N. A., Coates, P. J., Lorimore, S. A. & Wright, E. G. 2012 Radiobiology and environmental security. Mothersill, C. E., Korogodina, V. & Seymour, C. B. (eds.). Dordrecht: Springer , p. 141-151 11 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  428. MR real-time tracking of hepatic motion during respiration in a Thiel Soft-fix cadaver

    Cox, B. F., McLeod, H., Rube, M., Vinnicombe, S., Holbrook, A. B., Eisma, R., Saliev, T., Karakitsios, I. & Melzer, A. 2012 In : Biomedizinische Technik. Biomedical Engineering. 57, Suppl. 1, p. 1049-1049 1 p.

    Research output: Contribution to journalArticle

  429. Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics

    Miyagi, S. J., Milne, A. M., Coughtrie, M. W. H. & Collier, A. C. 2012 In : Drug Metabolism and Disposition. 40, 7, p. 1321-1327 7 p.

    Research output: Contribution to journalArticle

  430. Neuroprotective effects of sulforaphane after contusive spinal cord injury

    Benedict, A. L., Mountney, A., Hurtado, A., Bryan, K. E., Schnaar, R. L., Dinkova-Kostova, A. T. & Talalay, P. 2012 In : Journal of Neurotrauma. 29, 16, p. 2576-2586 11 p.

    Research output: Contribution to journalArticle

  431. New standards of care in the management of the axilla

    Thompson, A. M. 2012 In : Current Opinion in Oncology. 24, 6, p. 605-611 7 p.

    Research output: Contribution to journalArticle

  432. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene. 32, p. 3765-3781 17 p.

    Research output: Contribution to journalArticle

  433. Nrf2 orchestrates fuel partitioning for cell proliferation

    Hayes, J. D. & Ashford, M. L. J. 2012 In : Cell Metabolism. 16, 2, p. 139-141 3 p.

    Research output: Contribution to journalArticle

  434. NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity

    Leigh, I. , Inman, G. J. & 21 others Wang, H., Lee, S., Lo Nigro, C., Lattanzio, L., Merlano, M., Monteverde, M., Matin, R., Purdie, K., Mladkova, N., Bergamaschi, D., Harwood, C., Syed, N., Szlosarek, P., Briasoulis, E., McHugh, A., Thompson, A., Evans, A., Fleming, C., Hatzimichael, E., Proby, C. & Crook, T. 2012 In : British Journal of Cancer. 106, 8, p. 1446-52 7 p.

    Research output: Contribution to journalArticle

  435. NT5E CpG island methylation is a favourable breast cancer biomarker

    Lo Nigro, C., Monteverde, M., Lee, S., Lattanzio, L., Vivenza, D., Comino, A., Syed, N., McHugh, A., Wang, H., Proby, C., Garrone, O., Merlano, M., Hatzimichael, E., Briasoulis, E., Gojis, O., Palmieri, C., Jordan, L., Quinlan, P., Thompson, A. & Crook, T. 2012 In : British Journal of Cancer. 107, 1, p. 75-83 9 p.

    Research output: Contribution to journalArticle

  436. Optimizing sonication protocols for transthoracic focused ultrasound surgery

    Gao, J., Volovick, A., Cao, R., Nabi, G., Cochran, S., Melzer, A. & Huang, Z. 2012 12th International Symposium on Therapeutic Ultrasound. Meairs, S. (ed.). Melville: American Institute of Physics, p. 146-151 6 p. (AIP Conference Proceedings; vol. 1503)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  437. Optimizing sonication protocols for transthoracic focused ultrasound surgery

    Gao, J., Volovick, A., Cao, R., Nabi, G., Cochran, S., Melzer, A. & Huang, Z. 2012

    Research output: Contribution to conferencePoster

  438. Organ motion tracking in USgFUS - a feasibility study using sonoelastography

    Xiao, X., Le, N., Corner, G., Nabi, G., Melzer, A. & Huang, Z. 2012 12th International Symposium on Therapeutic Ultrasound. Meairs, S. (ed.). Melville: American Institute of Physics, p. 135-139 5 p. (AIP Conference Proceedings; vol. 1503)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  439. Precursors of vulvovaginal squamous cell carcinoma

    Oparka, R. & Herrington, C. S. 2012 Pathology of the vulva and vagina. Brown, L. (ed.). London: Springer , p. 147-166 20 p. (Essentials of diagnostic gynecological pathology)

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  440. Pre-pregnancy, pregnancy and lactation

    Anderson, A. S. 2012 Essentials of human nutrition. Mann, J. & Truswell, A. S. (eds.). 4 ed. New York: Oxford University Press, p. 523-536 14 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  441. Promoter methylation of argininosuccinate synthetase-1 sensitises lymphomas to arginine deiminase treatment, autophagy and caspase-dependent apoptosis

    Delage, B., Luong, P., Maharaj, L., O'Riain, C., Syed, N., Crook, T., Hatzimichael, E., Papoudou-Bai, A., Mitchell, T. J., Whittaker, S. J., Cerio, R., Gribben, J., Lemoine, N., Bomalaski, J., Li, C-F., Joel, S., Fitzgibbon, J., Chen, L-T. & Szlosarek, P. W. 2012 In : Cell Death and Disease. 3, 7, e342

    Research output: Contribution to journalArticle

  442. Radiation-induced bone marrow apoptosis, inflammatory bystander-type signaling and tissue cytotoxicity

    Mukherjee, D., Coates, P. J., Rastogi, S., Lorimore, S. A. & Wright, E. G. 2012 In : International Journal of Radiation Biology.

    Research output: Contribution to journalArticle

  443. Rapid 3D human ribcage and kidney modeling for transcostal HIFU surgery

    Cao, R., Gao, J., Melzer, A., Nabi, G. & Huang, Z. 2012 12th International Symposium on Therapeutic Ultrasound. Meairs, S. (ed.). Melville: American Institute of Physics, p. 95-100 6 p. (AIP Conference Proceedings; vol. 1503)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  444. Real-time organ motion tracking in high intensity ultrasound treatment using sonoelastography: a feasibility study

    Xiao, X., Huang, Z., Melzer, A., Corner, G. & Nabi, G. 2012

    Research output: Contribution to conferenceAbstract

  445. Site-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBP) CpG island in breast cancer is associated with metastatic relapse

    Palmieri, C., Monteverde, M., Lattanzio, L., Gojis, O., Rudraraju, B., Fortunato, M., Syed, N., Thompson, A., Garrone, O., Merlano, M., Lo Nigro, C. & Crook, T. 2012 In : British Journal of Cancer. 107, 4, p. 732-738 7 p.

    Research output: Contribution to journalArticle

  446. Spironolactone and risk of incident breast cancer in women older than 55 years: retrospective, matched cohort study

    Mackenzie, I. S., Macdonald, T. M., Thompson, A., Morant, S. & Wei, L. 2012 In : British Medical Journal. 345, p. e4447 12 p., e4447

    Research output: Contribution to journalArticle

  447. Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP Axis

    Rada, P., Rojo, A. I., Evrard-Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García-Mayoral, M. F., Van Leuven, F., Hayes, J. D., Bertho, G. & Cuadrado, A. 2012 In : Molecular and Cellular Biology. 32, 17, p. 3486-99 14 p.

    Research output: Contribution to journalArticle

  448. Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins

    Boldrup, L., Coates, P. J., Wahlgren, M., Laurell, G. & Nylander, K. 2012 In : Journal of Carcinogenesis. 11, 1, p. 18

    Research output: Contribution to journalArticle

  449. Sulfotransferases

    Coughtrie, M. W. H. 2012 Metabolism of Drugs and Other Xenobiotics. Anzenbacher, P. & Zanger, U. M. (eds.). Germany: Wiley-VCH , p. 117-145 29 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  450. Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease

    Castro-Caldas, M., Carvalho, A. N., Rodrigues, E., Henderson, C. J., Wolf, C. R., Rodrigues, C. M. P. & Gama, M. J. 2012 In : Molecular Neurobiology. 46, 2, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  451. The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma

    Hatzimichael, E. , Lo Nigro, C. , Lattanzio, L. , Syed, N. , Shah, R. , Dasoula, A. , Janczar, K. , Vivenza, D. , Monteverde, M. , Merlano, M. , Papoudou-Bai, A. , Bai, M. , Schmid, P. , Stebbing, J. , Bower, M. , Dyer, M. J. S. , Karran, L. E. , Elguetakarstegl, C. , Farrell, P. J. , Thompson, A. & 2 others Briasoulis, E. & Crook, T. 2012 In : British Journal of Cancer. 107, 8, p. 1423-1432 10 p.

    Research output: Contribution to journalArticle

  452. The effect of ABCG2 transporter inhibition and ferrochelatase activity on PDT efficacy: an in-vivo study

    Barron, G., Woods, J. & Moseley, H. 2012 In : Lasers in Medical Science. 27, 5, p. 857

    Research output: Contribution to journalMeeting abstract

  453. The in vivo expression of radiation-induced chromosomal instability has an inflammatory mechanism

    Mukherjee, D., Coates, P. J., Lorimore, S. A. & Wright, E. G. 2012 In : Radiation Research. 177, 1, p. 18-24 7 p.

    Research output: Contribution to journalArticle

  454. The relationship between components of tumour inflammatory cell infiltrate and clinicopathological factors and survival in patients with primary operable invasive ductal breast cancer

    Mohammed, Z. M. A., Going, J. J., Edwards, J., Elsberger, B., Doughty, J. C. & McMillan, D. C. 2012 In : British Journal of Cancer. 107, 5, p. 864-873 10 p.

    Research output: Contribution to journalArticle

  455. Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism

    Westendorf, A. F., Woods, J. A., Korpis, K., Farrer, N. J., Salassa, L., Robinson, K., Appleyard, V., Murray, K., Grünert, R., Thompson, A. M., Sadler, P. J. & Bednarski, P. J. 2012 In : Molecular Cancer Therapeutics. 11, 9, p. 1894-1904 11 p.

    Research output: Contribution to journalArticle

  456. Transcriptional profiling of formalin fixed paraffin embedded tissue: pitfalls and recommendations for identifying biologically relevant changes

    Rentoft, M., Coates, P. J., Laurell, G. & Nylander, K. 2012 In : PLoS ONE. 7, 4, p. - 8 p., e35276

    Research output: Contribution to journalArticle

  457. Transforming Growth Factor-β directly induces PUMA during the rapid induction of apoptosis in Myc-driven B-cell lymphomas.

    Spender, L. C., Carter, M. J., O'Brien, D. I., Clark, L. J., Yu, J., Michalak, E. M., Happo, L., Cragg, M. S. & Inman, G. J. 2012 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  458. Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling

    Bose, A., Teh, M-T., Hutchison, I. L., Wan, H., Leigh, I. M. & Waseem, A. 2012 In : PLoS ONE. 7, 6, e38599

    Research output: Contribution to journalArticle

  459. Ultraviolet A1 phototherapy: a British Photodermatology Group workshop report

    Kerr, A. C., Ferguson, J., Attili, S. K., Beattie, P. E., Coleman, A. J., Dawe, R. S., Eberlein, B., Goulden, V., Ibbotson, S. H., Menage, H. D. P., Moseley, H., Novakovic, L., Walker, S. L., Woods, J. A., Young, A. R. & Sarkany, R. P. E. 2012 In : Clinical and Experimental Dermatology. 37, 3, p. 219-226 8 p.

    Research output: Contribution to journalArticle

  460. Nrf2-mediated induction of antioxidant response element-driven gene expression by flavonoids is dependent on their chemical structure

    Xiao, H., Hourihan, J. M., Brown, L., McMahon, M., Stewart, D. & Hayes, J. D. 18 Dec 2011 In : Toxicology. 290, 2-3, p. 126-127 2 p.

    Research output: Contribution to journalBook/Film/Article review

  461. mTORC2 targets AGC kinases through Sin1-dependent recruitment

    Cameron, A. J. M., Linch, M. D., Saurin, A. T., Escribano, C. & Parker, P. J. 15 Oct 2011 In : Biochemical Journal. 439, p. 287-297 11 p.

    Research output: Contribution to journalArticle

  462. Absolute SILAC-compatible expression strain allows SUMO-2 copy number determination in clinical samples

    Matic, I., Jaffray, E. G., Oxenham, S. K., Groves, M. J., Barratt, C. L. R., Tauro, S., Stanley-Wall, N. R. & Hay, R. T. Oct 2011 In : Journal of Proteome Research. 10, 10, p. 4869-4875 7 p.

    Research output: Contribution to journalArticle

  463. Epigenetic Dysregulation of Novel Genes in Melanoma

    Wang, H., McHugh, A., Matin, R., Fleming, C., Leigh, I., Harwood, C., Crook, T., Inman, G. & Proby, C. Sep 2011 In : Journal of Investigative Dermatology. 131, p. S114-S114 1 p.

    Research output: Contribution to journalBook/Film/Article review

  464. A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

    Girardini, J. E., Napoli, M., Piazza, S., Rustighi, A., Marotta, C., Radaelli, E., Capaci, V., Jordan, L., Quinlan, P., Thompson, A., Mano, M., Rosato, A., Crook, T., Scanziani, E., Means, A. R., Lozano, G., Schneider, C. & Del Sal, G. 12 Jul 2011 In : Cancer Cell. 20, 1, p. 79-91 13 p.

    Research output: Contribution to journalArticle

  465. Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway

    Terrier, O., Josset, L., Textoris, J., Marcel, V., Cartet, G., Ferraris, O., N'Guyen, C., Lina, B., Diaz, J-J., Bourdon, J-C. & Rosa-Calatrava, M. 8 Jun 2011 In : Virology Journal. 8, 11 p., 285

    Research output: Contribution to journalArticle

  466. The role of P63 in cancer, stem cells and cancer stem cells

    Nekulova, M., Holcakova, J., Coates, P. & Vojtesek, B. Jun 2011 In : Cellular & Molecular Biology Letters. 16, 2, p. 296-327 32 p.

    Research output: Contribution to journalScientific review

  467. Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

    Saurin, A. T., van der Waal, M. S., Medema, R. H., Lens, S. M. A. & Kops, G. J. P. L. May 2011 In : Nature Communications. 2, 9 p., ARTN 316

    Research output: Contribution to journalArticle

  468. Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model

    Levova, K., Moserova, M., Kotrbova, V., Sulc, M., Henderson, C. J., Wolf, C. R., Phillips, D. H., Frei, E., Schmeiser, H. H., Mares, J., Arlt, V. M. & Stiborova, M. May 2011 In : Toxicological Sciences. 121, 1, p. 43-56 14 p.

    Research output: Contribution to journalArticle

  469. Epigenetic dysregulation of novel candidate genes in malignant melanoma

    Wang, H., McHugh, A. T., Matin, R., Fleming, C., Leigh, I. M., Harwood, C., Crook, T., Inman, G. & Proby, C. 11 Apr 2011 In : British Journal of Dermatology. 164, 4, p. 916-916 1 p.

    Research output: Contribution to journalBook/Film/Article review

  470. Erratum - DPY19L2 Deletion as a Major Cause of Globozoospermia

    Koscinski, I., Ellnati, E., Fossard, C., Redin, C., Muller, J., de la Calle, J. V., Schmitt, F., Ben Khelifa, M., Ray, P. F., Kilani, Z., Barratt, C. L. R. & Viville, S. 8 Apr 2011 In : American Journal of Human Genetics. 88, 4, p. 517 1 p.

    Research output: Contribution to journalArticle

  471. DPY19L2 Deletion as a Major Cause of Globozoospermia

    Koscinski, I., Ellnati, E., Fossard, C., Redin, C., Muller, J., de la Calle, J. V., Schmitt, F., Ben Khelifa, M., Ray, P., Kilani, Z., Barratt, C. L. R. & Viville, S. 11 Mar 2011 In : American Journal of Human Genetics. 88, 2011, p. 344-350 7 p.

    Research output: Contribution to journalArticle

  472. Involvement of p53 in ribosomal RNA processing and translational control

    Ghayad, S. E., Belin, S., Morel, A-P., Hacot, S., Mertani, H. C., Vendrell, J., Bourdon, J-C., Prats, A-C., Puisieux, A. & Diaz, J-J. Mar 2011 In : Bulletin du Cancer. 98, S1, p. S30-S30 1 p.

    Research output: Contribution to journalMeeting abstract

  473. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

    Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D. & Cuadrado, A. Mar 2011 In : Molecular and Cellular Biology. 31, 6, p. 1121-1133 13 p.

    Research output: Contribution to journalArticle

  474. Control of nuclear HIPK2 localization and function by a SUMO interaction motif

    de la Vega, L., Fröbius, K., Moreno, R., Calzado, M. A., Geng, H. & Schmitz, M. L. Feb 2011 In : Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 2, p. 283-297 15 p.

    Research output: Contribution to journalArticle

  475. Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

    Bell, K. F., Al-Mubarak, B., Fowler, J. H., Baxter, P. S., Gupta, K., Tsujita, T., Chowdhry, S., Patani, R., Chandran, S., Horsburgh, K., Hayes, J. D. & Hardingham, G. E. 4 Jan 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 1, p. E1-E2 2 p.

    Research output: Contribution to journalLetter

  476. Diagnostic tools in male infertility-the question of sperm dysfunction

    Barratt, C. L. R., Mansell, S., Beaton, C., Tardif, S. & Oxenham, S. K. Jan 2011 In : Asian Journal of Andrology. 13, 1, p. 53-58 6 p.

    Research output: Contribution to journalScientific review

  477. A web-based data analytical tool for translational researchers

    Quinlan, P. R., Jordan, L. B., Purdie, C. A., Thompson, A. & Reed, C. 2011

    Research output: Contribution to conferenceAbstract

  478. Biological functions of p53 isoforms through evolution: lessons from animal and cellular models

    Marcel, V., Dichtel-Danjoy, M-L., Sagne, C., Hafsi, H., Ma, D., Ortiz-Cuaran, S., Olivier, M., Hall, J., Mollereau, B., Hainaut, P. & Bourdon, J-C. 2011 In : Cell Death & Differentiation. 18, 12, p. 1815-1824 10 p.

    Research output: Contribution to journalScientific review

  479. Breast

    James, J. J. & Evans, A. J. 2011 Clinical ultrasound. Allan, P. L., Baxter, G. M. & Weston, M. J. (eds.). 3rd ed. Edinburgh: Churchill Livingstone, Vol. 2, p. 987-1004 18 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  480. Calciphylaxis: a case series

    Veitch, D., Dobbie, H., Cerio, R., Wijesuriya, N., McGregor, J. M., Proby, C. M., Dhoat, S. & Harwood, C. A. 2011 In : British Journal of Dermatology. 165, S1, p. 25-26 2 p., P_13

    Research output: Contribution to journalSpecial issue

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