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Division of Cardiovascular & Diabetes Medicine

  1. Elevated plasma levels of MMP-12 are associated with atherosclerotic burden and symptomatic cardiovascular disease in subjects with type 2 diabetes

    Khan, F. , Belch, J. & 24 others Goncalves, I., Bengtsson, E., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Edsfeldt, A., Dunér, P., Fredrikson, G. N., Björkbacka, H., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Strain, D., Looker, H. C., Adams, F., Pinnoli, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V. & Nilsson, J. 27 Jul 2015 In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 7, p. 1723-1731 9 p.

    Research output: Contribution to journalArticle

  2. A review on the Hemodialysis Reliable Outflow (HeRO) graft for haemodialysis vascular access

    Al Shakarchi, J., Houston, J. G., Jones, R. G. & Inston, N. Jul 2015 In : European Journal of Vascular and Endovascular Surgery. 50, 1, p. 108-113 6 p.

    Research output: Contribution to journalArticle

  3. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., Macleod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & on behalf of the BeWEL team Jul 2015 In : Colorectal Disease. 17, 7, p. 589-594 6 p.

    Research output: Contribution to journalArticle

  4. Interventions to prevent non-critical care hospital acquired pneumonia – a systematic review

    McAuley, S. M., Price, R. J. G., Phillips, G., Marwick, C. A., McMurdo, M. E. T. & Witham, M. D. Jul 2015 In : European Geriatric Medicine. 6, 4, p. 336-340 5 p.

    Research output: Contribution to journalArticle

  5. NSAID exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity

    Morales, D. R., Guthrie, B., Lipworth, B. J., Jackson, C., Donnan, P. T. & Santiago, V. H. Jul 2015 In : Allergy. 70, 7, p. 828-835 8 p.

    Research output: Contribution to journalArticle

  6. A link between ATP and SUR2A: a novel mechanism explaining cardioprotection at high altitude

    Mohammed Abdul, K. S., Jovanovic, S., Du, Q., Sukhodub, A. & Jovanovic, A. 15 Jun 2015 In : International Journal of Cardiology. 189, p. 73-76 4 p.

    Research output: Contribution to journalLetter

  7. The Scylla and Charybdis of glucose control in childhood type 1 diabetes?

    McNeilly, A. D. & McCrimmon, R. J. 1 Jun 2015 In : Pediatric Diabetes. 16, 4, p. 235-241 7 p.

    Research output: Contribution to journalArticle

  8. Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Morris, A. D. & 26 others Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K., Hattersley, A. T., Walker, M., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M. Jun 2015 In : Diabetes. 64, 6, p. 2279-2285 7 p.

    Research output: Contribution to journalArticle

  9. Characterizing patients with chronic heart failure in community care after hospitalization: a potential role for ivabradine

    Elder, D. H., Mohan, M., Cochrane, L., Charles, H. & Lang, C. C. Jun 2015 In : Cardiovascular Therapeutics. 33, 3, p. 104-108 5 p.

    Research output: Contribution to journalArticle

  10. Defining cachexia in a renal population

    Reid, J., Noble, H., Davenport, A., Farrington, K., Fouque, D., Porter, S., Seres, D., Shields, J., Slee, A., Witham, M. D., Wright, M. & Maxwell, A. P. Jun 2015 In : Journal of Renal Care. 41, 2, p. 79-80 2 p.

    Research output: Contribution to journalEditorial

  11. Diazoxide improves hormonal counterregulatory responses to acute hypoglycemia in long-standing Type 1 Diabetes

    George, P. S., Tavendale, R., Palmer, C. N. A. & McCrimmon, R. J. Jun 2015 In : Diabetes. 64, 6, p. 2234-2241 8 p.

    Research output: Contribution to journalArticle

  12. Middle East respiratory syndrome: the need for better evidence in severe respiratory viral infections

    Abo-Leyah, H. & Chalmers, J. D. Jun 2015 In : Critical Care Medicine. 43, 6, p. 1344-1346 3 p.

    Research output: Contribution to journalEditorial

  13. Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome

    Rzepecka, J., Pineda, M. A., Al-Riyami, L., Rodgers, D. T., Huggan, J. K., Lumb, F. E., Khalaf, A. I., Meakin, P. J., Corbet, M., Ashford, M. L., Suckling, C. J., Harnett, M. M. & Harnett, W. Jun 2015 In : Journal of Autoimmunity. 60, p. 59-73 15 p.

    Research output: Contribution to journalArticle

  14. ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults

    Vijverberg, S. J. H., Koster, E. S., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Tse, S. M., Tantisira, K. G., Hawcutt, D. B., Francis, B., Pirmohamed, M., Pino-Yanes, M., Eng, C., Burchard, E. G., Palmer, C. N. A. & Maitland-van der Zee, A. H. Jun 2015 In : Clinical and Experimental Allergy. 45, 6, p. 1051-1059 9 p.

    Research output: Contribution to journalArticle

  15. Technical assessment of whole body angiography and cardiac function within a single MRI examination

    Gandy, S. J., Lambert, M., Belch, J. J. F., Cavin, I. D., Crowe, E., Littleford, R., Macfarlane, J. A., Matthew, S. Z., Martin, P., Nicholas, R. S., Struthers, A. D., Sullivan, F., Waugh, S. A., White, R. D., Weir-McCall, J. R. & Houston, J. G. Jun 2015 In : Clinical Radiology. 70, 6, p. 595-603 9 p.

    Research output: Contribution to journalArticle

  16. Enhanced mitochondrial superoxide scavenging does not Improve muscle insulin action in the high fat-fed mouse

    Lark, D. S., Kang, L., Lustig, M. E., Bonner, J. S., James, F. D., Neufer, P. D. & Wasserman, D. H. 19 May 2015 In : PLoS ONE. 10, 5, 11 p., e0126732

    Research output: Contribution to journalArticle

  17. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

    Bell, K. F. S., Al-Mubarak, B., Martel, M. A., McKay, S., Wheelan, N., Hasel, P., Márkus, N. M., Baxter, P., Deighton, R. F., Serio, A., Bilican, B., Chowdhry, S., Meakin, P. J., Ashford, M. L. J., Wyllie, D. J. A., Scannevin, R. H., Chandran, S., Hayes, J. D. & Hardingham, G. E. 13 May 2015 In : Nature Communications. 6, 15 p., 7066

    Research output: Contribution to journalArticle

  18. Myocardial fibrosis in stroke survivors

    Wong, K., Sze, S., Wong, S., McSwiggan, S., Allgar, V., MacWalter, R. & Struthers, A. D. 6 May 2015 In : International Journal of Cardiology. 187, p. 138-140 3 p.

    Research output: Contribution to journalLetter

  19. State of the art review: management of bronchiectasis in adults

    Chalmers, J. D., Aliberti, S. & Blasi, F. 1 May 2015 In : European Respiratory Journal. 45, 5, p. 1446-1462 12 p.

    Research output: Contribution to journalArticle

  20. Association of organic cation transporter 1 with intolerance to metformin in Type 2 diabetes: a GoDARTS study

    Dujic, T., Zhou, K., Donnelly, L. A., Tavendale, R., Palmer, C. N. A. & Pearson, E. R. May 2015 In : Diabetes. 64, 5, p. 1786-1793 8 p.

    Research output: Contribution to journalArticle

  21. Asymptomatic and mild primary hyperparathyroidism

    Macfarlane, D. P., Yu, N. & Leese, G. P. May 2015 In : Annales d'Endocrinologie. 76, 2, p. 120-127 8 p.

    Research output: Contribution to journalArticle

  22. Effect of vitamin D supplementation on blood pressure: a systematic review and meta-analysis incorporating individual patient data

    Struthers, A. D. , Khan, F. , Witham, M. D. & 20 others Beveridge, L. A., Jorde, R., Scragg, R., Macdonald, H. M., Alvarez, J., Boxer, R., Dalbeni, A., Gepner, A. D., Isbel, N. M., Larsen, T., Nagpal, J., Petchey, W. G., Stricker, H., Stroebel, F., Tangpricha, V., Toxqui, L., Vaquero, M. P., Wamberg, L., Zittermann, A. & D-PRESSURE Collaboration May 2015 In : JAMA Internal Medicine. 175, 5, p. 745-754

    Research output: Contribution to journalArticle

  23. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

  24. Falls research: stumbling or striding?

    Clark, C. L., McMurdo, M. E. T. & Witham, M. D. May 2015 In : Age and Ageing. 44, 3, p. 350-352 2 p.

    Research output: Contribution to journalEditorial

  25. Mild hypoxia in vivo regulates cardioprotective SUR2A: A role for Akt and LDH

    Mohammed Abdul, K. S., Jovanović, S., Du, Q., Sukhodub, A. & Jovanović, A. May 2015 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1852, 5, p. 709-719 11 p.

    Research output: Contribution to journalArticle

  26. Preclinical feasibility of a technology framework for MRI-guided iliac angioplasty

    Rube, M. A., Fernandez-Gutierrez, F., Cox, B. F., Holbrook, A. B., Houston, J. G., White, R. D., McLeod, H., Fatahi, M. & Melzer, A. May 2015 In : International Journal of Computer Assisted Radiology and Surgery. 10, 5, p. 637-650 14 p.

    Research output: Contribution to journalArticle

  27. Reclaiming the name 'bronchiectasis'

    Chalmers, J. D. & Elborn, J. S. May 2015 In : Thorax. 70, 5, p. 399-400 2 p.

    Research output: Contribution to journalEditorial

  28. The effect of 222-nm UVC phototesting on healthy volunteer skin: a pilot study

    Woods, J. A., Evans, A., Forbes, P. D., Coates, P. J., Gardner, J., Valentine, R. M., Ibbotson, S. H., Ferguson, J., Fricker, C. & Moseley, H. May 2015 In : Photodermatology, Photoimmunology & Photomedicine. 31, 3, p. 159-166 8 p.

    Research output: Contribution to journalArticle

  29. The role of perceived barriers and objectively measured physical activity in adults aged 65-100

    Gellert, P., Witham, M. D., Crombie, I. K., Donnan, P. T., McMurdo, M. E. T. & Sniehotta, F. F. May 2015 In : Age and Ageing. 44, 3, p. 384-390 7 p.

    Research output: Contribution to journalArticle

  30. Tiotropium in asthma

    Lipworth, B. May 2015 In : The Lancet Respiratory Medicine. 3, 5, p. e16-e17 2 p.

    Research output: Contribution to journalLetter

  31. β2-Adrenergic receptor Gly16Arg polymorphism and impaired asthma control in corticosteroid-treated asthmatic adults

    Manoharan, A., Griffin, B., Lipworth, J., Berg, J., Andrew, N., Jackson, C. & Lipworth, B. May 2015 In : Annals of Allergy, Asthma & Immunology. 114, 5, p. 421-423 3 p.

    Research output: Contribution to journalLetter

  32. Genetically Determined Height and Coronary Artery Disease

    Nelson, C. P. , Hamby, S. E. , Saleheen, D. , Hopewell, J. C. , Zeng, L. , Assimes, T. L. , Kanoni, S. , Willenborg, C. , Burgess, S. , Amouyel, P. , Anand, S. , Blankenberg, S. , Boehm, B. O. , Clarke, R. J. , Collins, R. , Dedoussis, G. , Farrall, M. , Franks, P. W. , Groop, L. , Hall, A. S. & 37 others Hamsten, A., Hengstenberg, C., Hovingh, G. K., Ingelsson, E., Kathiresan, S., Kee, F., König, I. R., Kooner, J., Lehtimäki, T., März, W., McPherson, R., Metspalu, A., Nieminen, M. S., O'Donnell, C. J., Palmer, C. N. A., Peters, A., Perola, M., Reilly, M. P., Ripatti, S., Roberts, R., Salomaa, V., Shah, S. H., Schreiber, S., Siegbahn, A., Thorsteinsdottir, U., Veronesi, G., Wareham, N., Willer, C. J., Zalloua, P. A., Erdmann, J., Deloukas, P., Watkins, H., Schunkert, H., Danesh, J., Thompson, J. R., Samani, N. J. & CARDIoGRAM+C4D Consortium 8 Apr 2015 In : New England Journal of Medicine. 372, 17, p. 1608-1618

    Research output: Contribution to journalArticle

  33. Dose-dependent effects of Allopurinol on human foreskin fibroblast cell and human umbilical vein endothelial cell under hypoxia

    Sun, Y., George, J. & Rocha, S. 1 Apr 2015 In : PLoS ONE. 10, 4, 12 p., e0123649

    Research output: Contribution to journalArticle

  34. Dose-dependent effects of Allopurinol on human foreskin fibroblast cells and human umbilical vein endothelial cells under hypoxia

    Sun, Y., George, J. & Rocha, S. 1 Apr 2015 In : PLoS ONE. 10, 4, 12 p., e0123649

    Research output: Contribution to journalArticle

  35. A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome

    Aung, T. , Ozaki, M. , Mizoguchi, T. , Allingham, R. R. , Li, Z. , Haripriya, A. , Nakano, S. , Uebe, S. , Harder, J. M. , Chan, A. S. Y. , Lee, M. C. , Burdon, K. P. , Astakhov, Y. S. , Abu-Amero, K. K. , Zenteno, J. C. , Nilgün, Y. , Zarnowski, T. , Pakravan, M. , Safieh, L. A. , Jia, L. & 142 others Wang, Y. X., Williams, S., Paoli, D., Schlottmann, P. G., Huang, L., Sim, K. S., Foo, J. N., Nakano, M., Ikeda, Y., Kumar, R. S., Ueno, M., Manabe, S., Hayashi, K., Kazama, S., Ideta, R., Mori, Y., Miyata, K., Sugiyama, K., Higashide, T., Chihara, E., Inoue, K., Ishiko, S., Yoshida, A., Yanagi, M., Kiuchi, Y., Aihara, M., Ohashi, T., Sakurai, T., Sugimoto, T., Chuman, H., Matsuda, F., Yamashiro, K., Gotoh, N., Miyake, M., Astakhov, S. Y., Osman, E. A., Al-Obeidan, S. A., Owaidhah, O., Al-Jasim, L., Al Shahwan, S., Fogarty, R. A., Leo, P., Yetkin, Y., Oğuz, Ç., Kanavi, M. R., Beni, A. N., Yazdani, S., Akopov, E. L., Toh, K-Y., Howell, G. R., Orr, A. C., Goh, Y., Meah, W. Y., Peh, S. Q., Kosior-Jarecka, E., Lukasik, U., Krumbiegel, M., Vithana, E. N., Wong, T. Y., Liu, Y., Koch, A. E. A., Challa, P., Rautenbach, R. M., Mackey, D. A., Hewitt, A. W., Mitchell, P., Wang, J. J., Ziskind, A., Carmichael, T., Ramakrishnan, R., Narendran, K., Venkatesh, R., Vijayan, S., Zhao, P., Chen, X., Guadarrama-Vallejo, D., Cheng, C. Y., Perera, S. A., Husain, R., Ho, S-L., Welge-Luessen, U-C., Mardin, C., Schloetzer-Schrehardt, U., Hillmer, A. M., Herms, S., Moebus, S., Nöthen, M. M., Weisschuh, N., Shetty, R., Ghosh, A., Teo, Y. Y., Brown, M. A., Lischinsky, I., Crowston, J. G., Coote, M., Zhao, B., Sang, J., Zhang, N., You, Q., Vysochinskaya, V., Founti, P., Chatzikyriakidou, A., Lambropoulos, A., Anastasopoulos, E., Coleman, A. L., Wilson, M. R., Rhee, D. J., Kang, J. H., May-Bolchakova, I., Heegaard, S., Mori, K., Alward, W. L. M., Jonas, J. B., Xu, L., Liebmann, J. M., Chowbay, B., Schaeffeler, E., Schwab, M., Lerner, F., Wang, N., Yang, Z., Frezzotti, P., Kinoshita, S., Fingert, J. H., Inatani, M., Tashiro, K., Reis, A., Edward, D. P., Pasquale, L. R., Kubota, T., Wiggs, J. L., Pasutto, F., Topouzis, F., Dubina, M., Craig, J. E., Yoshimura, N., Sundaresan, P., John, S. W. M., Ritch, R., Hauser, M. A., Khor, C-C. & Wellcome Trust Case Control Consortium 2 Apr 2015 In : Nature Genetics. 47, 4, p. 387-392 6 p.

    Research output: Contribution to journalLetter

  36. Challenges in the development of new therapies for bronchiectasis

    Chalmers, J. D., Loebinger, M. & Aliberti, S. Apr 2015 In : Expert Opinion on Pharmacotherapy. 16, 6, p. 833-850 18 p.

    Research output: Contribution to journalArticle

  37. Changes in the association between health complaint frequency and medicine use among adolescents in Scotland between 1998 and 2010

    Levin, K. A., Whitehead, R., Andersen, A., Levin, D., Gobina, I. & Holstein, B. Apr 2015 In : Journal of Psychosomatic Research. 78, 4, p. 371-376 6 p.

    Research output: Contribution to journalArticle

  38. Ethnicity and risk of cardiovascular disease (CVD): 4.8 year follow-up of patients with type 2 diabetes living in Scotland

    Malik, M. O., Govan, L., Petrie, J. R., Ghouri, N., Leese, G., Fischbacher, C., Colhoun, H., Philip, S., Wild, S., McCrimmon, R., Sattar, N. & on behalf of Scottish Diabetes Research Network (SDRN) Epidemiology group Apr 2015 In : Diabetologia. 58, 4, p. 716-725 10 p.

    Research output: Contribution to journalArticle

  39. HCV treatment rates and sustained viral response among people who inject drugs in seven UK sites: real world results and modelling of treatment impact

    Martin, N. K., Foster, G. R., Vilar, J., Ryder, S., Cramp, M. E., Gordon, F., Dillon, J. F., Craine, N., Busse, H., Clements, A., Hutchinson, S. J., Ustianowski, A., Ramsay, M., Goldberg, D. J., Irving, W., Hope, V., De Angelis, D., Lyons, M., Vickerman, P. & Hickman, M. Apr 2015 In : Journal of Viral Hepatitis. 22, 4, p. 399-408 10 p.

    Research output: Contribution to journalArticle

  40. Nucleoside diphosphate kinases (NDPKs) in animal development

    Takács-Vellai, K., Vellai, T., Farkas, Z. & Mehta, A. Apr 2015 In : Cellular and Molecular Life Sciences. 72, 8, p. 1447-1462 16 p.

    Research output: Contribution to journalArticle

  41. Does offering an incentive payment improve recruitment to clinical trials and increase the proportion of socially deprived and elderly participants?

    Jennings, C. G., MacDonald, T. M., Wei, L., Brown, M. J., McConnachie, L. & Mackenzie, I. S. 7 Mar 2015 In : Trials. 16, 80, 9 p.

    Research output: Contribution to journalArticle

  42. A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain

    Meng, W., Deshmukh, H. A., van Zuydam, N. R., Liu, Y., Donnelly, L. A., Zhou, K., Wellcome Trust Case Control Consortium 2 (WTCCC2), Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, Morris, A. D., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H. Mar 2015 In : European Journal of Pain. 19, 3, p. 392-399 8 p.

    Research output: Contribution to journalArticle

  43. Comparison of vortical structures induced by arteriovenous grafts using vector doppler ultrasound

    Kokkalis, E., Cookson, A. N., Stonebridge, P. A., Corner, G. A., Houston, J. G. & Hoskins, P. R. Mar 2015 In : Ultrasound in Medicine and Biology. 41, 3, p. 760-774 15 p.

    Research output: Contribution to journalArticle

  44. Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome: a randomised controlled trial

    Witham, M. D., Adams, F., McSwiggan, S., Kennedy, G., Kabir, G., Belch, J. J. F. & Khan, F. Mar 2015 In : Nutrition, Metabolism and Cardiovascular Diseases. 25, 3, p. 287-294 8 p.

    Research output: Contribution to journalArticle

  45. Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation

    Wypijewski, K. J., Tinti, M., Chen, W., Lamont, D., Ashford, M. L. J., Calaghan, S. C. & Fuller, W. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 596-608 13 p.

    Research output: Contribution to journalArticle

  46. Old drugs for bad bugs-aerosolized antibiotics in ventilator-associated pneumonia

    McAllister, K. & Chalmers, J. D. Mar 2015 In : Critical Care Medicine. 43, 3, p. 697-698 2 p.

    Research output: Contribution to journalEditorial

  47. Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis

    Levin, D. , Bell, S. , Sund, R. , Hartikainen, S. A. , Tuomilehto, J. , Pukkala, E. , Keskimäki, I. , Badrick, E. , Renehan, A. G. , Buchan, I. E. , Bowker, S. L. , Minhas-Sandhu, J. K. , Zafari, Z. , Marra, C. , Johnson, J. A. , Stricker, B. H. , Uitterlinden, A. G. , Hofman, A. , Ruiter, R. , de Keyser, C. E. & 5 others MacDonald, T. M., Wild, S. H., McKeigue, P. M., Colhoun, H. M. & on behalf of the Scottish Diabetes Research Network Epidemiology Group and the Diabetes and Cancer Research Consortium Mar 2015 In : Diabetologia. 58, 3, p. 493-504 12 p.

    Research output: Contribution to journalArticle

  48. Review of the British Thoracic Society Winter Meeting 2014, 3-5 December, London, UK

    Greening, N. J., José, R. J., Chalmers, J. D., Janes, S. M. & on behalf of the BTS Science and Research Committee Mar 2015 In : Thorax. 70, 3, p. 278-283 6 p.

    Research output: Contribution to journalArticle

  49. Genetic studies of body mass index yield new insights for obesity biology

    Morris, A. D. & 482 others Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Mägi, R., Randall, J. C., Winkler, T. W., Wood, A. R., Workalemahu, T., Faul, J. D., Smith, J. A., Hua Zhao, J., Zhao, W., Chen, J., Fehrmann, R., Hedman, Å. K., Karjalainen, J., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bolton, J. L., Bragg-Gresham, J. L., Buyske, S., Demirkan, A., Deng, G., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Goel, A., Gong, J., Jackson, A. U., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Medland, S. E., Nalls, M. A., Palmer, C. D., Pasko, D., Pechlivanis, S., Peters, M. J., Prokopenko, I., Shungin, D., Stančáková, A., Strawbridge, R. J., Ju Sung, Y., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van Setten, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Isaacs, A., Albrecht, E., Ärnlöv, J., Arscott, G. M., Attwood, A. P., Bandinelli, S., Barrett, A., Bas, I. N., Bellis, C., Bennett, A. J., Berne, C., Blagieva, R., Blüher, M., Böhringer, S., Bonnycastle, L. L., Böttcher, Y., Boyd, H. A., Bruinenberg, M., Caspersen, I. H., Ida Chen, Y-D., Clarke, R., Daw, E. W., de Craen, A. J. M., Delgado, G., Dimitriou, M., Doney, A. S. F., Eklund, N., Estrada, K., Eury, E., Folkersen, L., Fraser, R. M., Garcia, M. E., Geller, F., Giedraitis, V., Gigante, B., Go, A. S., Golay, A., Goodall, A. H., Gordon, S. D., Gorski, M., Grabe, H-J., Grallert, H., Grammer, T. B., Gräßler, J., Grönberg, H., Groves, C. J., Gusto, G., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hengstenberg, C., Holmen, O., Hottenga, J-J., James, A. 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A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männistö, S., Marette, A., Matise, T. C., McKenzie, C. A., McKnight, B., Moll, F. L., Morris, A. P., Murray, J. C., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Madden, P. A. F., Pasterkamp, G., Peden, J. F., Peters, A., Postma, D. S., Pramstaller, P. P., Price, J. F., Qi, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ridker, P. M., Rioux, J. D., Ritchie, M. D., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schunkert, H., Schwarz, P. E. H., Sever, P., Shuldiner, A. R., Sinisalo, J., Stolk, R. P., Strauch, K., Tönjes, A., Trégouët, D-A., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M-C., Völker, U., Waeber, G., Willemsen, G., Witteman, J. C., Zillikens, M. C., Adair, L. S., Amouyel, P., Asselbergs, F. W., Assimes, T. L., Bochud, M., Boehm, B. O., Boerwinkle, E., Bornstein, S. R., Bottinger, E. P., Bouchard, C., Cauchi, S., Chambers, J. C., Chanock, S. J., Cooper, R. 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M., Scherag, A., Willer, C. J., Boehnke, M., Mohlke, K. L., Lindgren, C. M., Beckmann, J. S., Barroso, I., North, K. E., Ingelsson, E., Hirschhorn, J. N., Loos, R. J. F., Speliotes, E. K. & LifeLines Cohort Study 12 Feb 2015 In : Nature. 518, 7538, p. 197-206 10 p.

    Research output: Contribution to journalArticle

  50. New genetic loci link adipose and insulin biology to body fat distribution

    Morris, A. D. & 406 others Shungin, D., Winkler, T. W., Croteau-Chonka, D. C., Ferreira, T., Locke, A. E., Mägi, R., Strawbridge, R. J., Pers, T. H., Fischer, K., Justice, A. E., Workalemahu, T., Wu, J. M. W., Buchkovich, M. L., Heard-Costa, N. L., Roman, T. S., Drong, A. W., Song, C., Gustafsson, S., Day, F. R., Esko, T., Fall, T., Kutalik, Z., Luan, J., Randall, J. C., Scherag, A., Vedantam, S., Wood, A. R., Chen, J., Fehrmann, R., Karjalainen, J., Kahali, B., Liu, C-T., Schmidt, E. M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J. L., Buyske, S., Demirkan, A., Ehret, G. B., Feitosa, M. F., Goel, A., Jackson, A. U., Johnson, T., Kleber, M. E., Kristiansson, K., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Palmer, C. D., Pasko, D., Pechlivanis, S., Peters, M. J., Prokopenko, I., Stančáková, A., Ju Sung, Y., Tanaka, T., Teumer, A., Van Vliet-Ostaptchouk, J. V., Yengo, L., Zhang, W., Albrecht, E., Ärnlöv, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blüher, M., Böhringer, S., Bonnet, F., Böttcher, Y., Bruinenberg, M., Carba, D. B., Caspersen, I. H., Clarke, R., Daw, E. W., Deelen, J., Deelman, E., Delgado, G., Doney, A. S. F., Eklund, N., Erdos, M. R., Estrada, K., Eury, E., Friedrich, N., Garcia, M. E., Giedraitis, V., Gigante, B., Go, A. S., Golay, A., Grallert, H., Grammer, T. B., Gräßler, J., Grewal, J., Groves, C. J., Haller, T., Hallmans, G., Hartman, C. A., Hassinen, M., Hayward, C., Heikkilä, K., Herzig, K-H., Helmer, Q., Hillege, H. L., Holmen, O., Hunt, S. C., Isaacs, A., Ittermann, T., James, A. L., Johansson, I., Juliusdottir, T., Kalafati, I-P., Kinnunen, L., Koenig, W., Kooner, I. K., Kratzer, W., Lamina, C., Leander, K., Lee, N. R., Lichtner, P., Lind, L., Lindström, J., Lobbens, S., Lorentzon, M., Mach, F., Magnusson, P. K. E., Mahajan, A., McArdle, W. L., Menni, C., Merger, S., Mihailov, E., Milani, L., Mills, R., Moayyeri, A., Monda, K. L., Mooijaart, S. P., Mühleisen, T. W., Mulas, A., Müller, G., Müller-Nurasyid, M., Nagaraja, R., Nalls, M. A., Narisu, N., Glorioso, N., Nolte, I. M., Olden, M., Rayner, N. W., Renstrom, F., Ried, J. S., Robertson, N. R., Rose, L. M., Sanna, S., Scharnagl, H., Scholtens, S., Sennblad, B., Seufferlein, T., Sitlani, C. M., Vernon Smith, A., Stirrups, K., Stringham, H. M., Sundström, J., Swertz, M. A., Swift, A. J., Syvänen, A-C., Tayo, B. O., Thorand, B., Thorleifsson, G., Tomaschitz, A., Troffa, C., van Oort, F. V. A., Verweij, N., Vonk, J. M., Waite, L. L., Wennauer, R., Wilsgaard, T., Wojczynski, M. K., Wong, A., Zhang, Q., Hua Zhao, J., Brennan, E. P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi, A. G., Hedman, Å. K., Hivert, M-F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton, R. P., Ma, B., McKnight, A. J., McPherson, R., Metspalu, A., Min, J. L., Moffatt, M. F., Montgomery, G. W., Murabito, J. M., Nicholson, G., Nyholt, D. R., Olsson, C., Perry, J. R. B., Reinmaa, E., Salem, R. M., Sandholm, N., Schadt, E. E., Scott, R. A., Stolk, L., Vallejo, E. E., Westra, H-J., Zondervan, K. T., Amouyel, P., Arveiler, D., Bakker, S. J. L., Beilby, J., Bergman, R. N., Blangero, J., Brown, M. J., Burnier, M., Campbell, H., Chakravarti, A., Chines, P. S., Claudi-Boehm, S., Collins, F. S., Crawford, D. C., Danesh, J., de Faire, U., de Geus, E. J. C., Dörr, M., Erbel, R., Eriksson, J. G., Farrall, M., Ferrannini, E., Ferrières, J., Forouhi, N. G., Forrester, T., Franco, O. H., Gansevoort, R. T., Gieger, C., Gudnason, V., Haiman, C. A., Harris, T. B., Hattersley, A. T., Heliövaara, M., Hicks, A. A., Hingorani, A. D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S. E., Hyppönen, E., Illig, T., Jarvelin, M-R., Johansen, B., Jousilahti, P., Jula, A. M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi, S. M., Kooner, J. S., Kooperberg, C., Kovacs, P., Kraja, A. T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männistö, S., Marette, A., Matise, T. C., McKenzie, C. A., McKnight, B., Musk, A. W., Möhlenkamp, S., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Palmer, L. J., Penninx, B. W., Peters, A., Pramstaller, P. P., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ridker, P. M., Ritchie, M. D., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Shuldiner, A. R., Staessen, J. A., Steinthorsdottir, V., Stolk, R. P., Strauch, K., Tönjes, A., Tremblay, A., Tremoli, E., Vohl, M-C., Völker, U., Vollenweider, P., Wilson, J. F., Witteman, J. C., Adair, L. S., Bochud, M., Boehm, B. O., Bornstein, S. R., Bouchard, C., Cauchi, S., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Cooper, R. S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H-J., Hamsten, A., Hui, J., Hveem, K., Jöckel, K-H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., März, W., Munroe, P. B., Njølstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Pérusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T. E., Saleheen, D., Sinisalo, J., Slagboom, P. E., Snieder, H., Spector, T. D., Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Veronesi, G., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H-E., Abecasis, G. R., Assimes, T. L., Berndt, S. I., Boehnke, M., Borecki, I. B., Deloukas, P., Franke, L., Frayling, T. M., Groop, L. C., Hunter, D. J., Kaplan, R. C., O'Connell, J. R., Qi, L., Schlessinger, D., Strachan, D. P., Stefansson, K., van Duijn, C. M., Willer, C. J., Visscher, P. M., Yang, J., Hirschhorn, J. N., Zillikens, M. C., McCarthy, M. I., Speliotes, E. K., North, K. E., Fox, C. S., Barroso, I., Franks, P. W., Ingelsson, E., Heid, I. M., Loos, R. J. F., Cupples, L. A., Morris, A. P., Lindgren, C. M., Mohlke, K. L. & ADIPOGen Consortium 12 Feb 2015 In : Nature. 518, 7538, p. 187-196 10 p.

    Research output: Contribution to journalArticle

  51. Community-acquired severity prediction- what are we predicting and why?

    Chalmers, J. D. 1 Feb 2015 In : QJM : an International Journal of Medicine. 102, 2, p. 173-174 2 p.

    Research output: Contribution to journalLetter

  52. A cardiovascular disease policy model that predicts life expectancy taking into account socioeconomic deprivation

    Lewsey, J. D., Lawson, K. D., Ford, I., Fox, K. A. A., Ritchie, L. D., Tunstall-Pedoe, H., Watt, G. C. M., Woodward, M., Kent, S., Neilson, M. & Briggs, A. H. Feb 2015 In : Heart (British Cardiac Society). 101, 3, p. 201-208 8 p.

    Research output: Contribution to journalArticle

  53. High fat feeding is associated with stimulation of the hypothalamic-pituitary-adrenal axis and reduced anxiety in the rat

    McNeilly, A. D., Stewart, C. A., Sutherland, C. & Balfour, D. J. K. Feb 2015 In : Psychoneuroendocrinology. 52, p. 272-280 9 p.

    Research output: Contribution to journalArticle

  54. Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

    Holland, P. R., Pannozzo, M. A., Bastin, M. E., McNeilly, A. D., Ferguson, K. J., Caughey, S., Jansen, M. A., Merrifield, G. D., Marshall, I., Mullins, J. J., Wardlaw, J. M., Sutherland, C. & Horsburgh, K. Feb 2015 In : Journal of Cerebral Blood Flow and Metabolism. 35, 2, p. 188-192 5 p.

    Research output: Contribution to journalArticle

  55. Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors

    Oram, R. A., McDonald, T. J., Shields, B. M., Hudson, M. M., Shepherd, M. H., Hammersley, S., Pearson, E. R., Hattersley, A. T. & on behalf of the UNITED Team Feb 2015 In : Diabetes Care. 38, 2, p. 323-328 6 p.

    Research output: Contribution to journalArticle

  56. True cadence and step accumulation are not equivalent: the effect of intermittent claudication on free-living cadence

    Stansfield, B., Clarke, C., Dall, P., Godwin, J., Holdsworth, R. & Granat, M. Feb 2015 In : Gait & Posture. 41, 2, p. 414-419 6 p.

    Research output: Contribution to journalArticle

  57. What is the impact of a country-wide scale-up in antiviral therapy on the characteristics and sustained viral response rates of patients treated for hepatitis C?

    McDonald, S. A., Innes, H. A., Hayes, P. C., Dillon, J. F., Mills, P. R., Goldberg, D. J., Barclay, S., Allen, S., Fox, R., Fraser, A., Kennedy, N., Bhattacharyya, D. & Hutchinson, S. J. Feb 2015 In : Journal of Hepatology. 62, 2, p. 262-268 7 p.

    Research output: Contribution to journalArticle

  58. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

    Morris, A. D. & 88 others Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J., Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N. P., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Syvänen, A-C., Trakalo, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Hanis, C. L., Seielstad, M., Wilson, J. G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G. L., Doney, A. S. F., Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M. E., Jørgensen, T., Kuusisto, J., Uusitupa, M., Salomaa, V., Spector, T. D., Palmer, C. N. A., Collins, F. S., Mohlke, K. L., Bergman, R. N., Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R. M., Prokopenko, I., Dupuis, J., Karpe, F., Groop, L., Laakso, M., Pedersen, O., Florez, J. C., Morris, A. P., Altshuler, D., Meigs, J. B., Boehnke, M., McCarthy, M. I., Lindgren, C. M., Gloyn, A. L. & On Behalf of the T2D-GENES consortium and GoT2D consortium 27 Jan 2015 In : PLoS Genetics. 11, 1, 25 p., e1004876

    Research output: Contribution to journalArticle

  59. Biological interpretation of genome-wide association studies using predicted gene functions

    Pers, T. H., Karjalainen, J. M., Chan, Y., Westra, H-J., Wood, A. R., Yang, J., Lui, J. C., Vedantam, S., Gustafsson, S., Esko, T., Frayling, T., Speliotes, E. K., Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Boehnke, M., Raychaudhuri, S., Fehrmann, R. S. N., Hirschhorn, J. N. & Franke, L. 19 Jan 2015 In : Nature Communications. 6, 9 p., 5890

    Research output: Contribution to journalArticle

  60. Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010

    Livingstone, S. J., Levin, D., Looker, H. C., Lindsay, R. S., Wild, S. H., Joss, N., Leese, G., Leslie, P., McCrimmon, R. J., Metcalfe, W., McKnight, J. A., Morris, A. D., Pearson, D. W. M., Petrie, J. R., Philip, S., Sattar, N. A., Traynor, J. P. & Colhoun, H. M. 6 Jan 2015 In : JAMA: the Journal of the American Medical Association. 313, 1, p. 37-44 8 p.

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  61. A systematic review of the prevalence of mildly abnormal liver function tests and associated health outcomes

    Radcke, S., Dillon, J. F. & Murray, A. L. Jan 2015 In : European Journal of Gastroenterology & Hepatology. 27, 1, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  62. An increased B-type natriuretic peptide in the absence of a cardiac abnormality identifies those whose left ventricular mass will increase over time

    Nadir, M. A., Gandy, S., Ireland, S., MacDonald, T., Dow, E., Houston, G., Lang, C. & Struthers, A. Jan 2015 In : JACC: Heart Failure. 3, 1, p. 87-93 7 p.

    Research output: Contribution to journalArticle

  63. Clinical relevance of house dust mite immunotherapy

    Lipworth, B. Jan 2015 In : Journal of Allergy and Clinical Immunology. 135, 1, p. 288-288 1 p.

    Research output: Contribution to journalLetter

  64. Ageing as a cross-cutting theme

    Witham, M. D. 2015

    Research output: Contribution to conferenceOther

  65. Both high and low HbA1c predict incident heart failure in type 2 diabetes mellitus

    Parry, H. M., Desmukh, H., Levin, D., Van Zuydam, N., Elder, D. H. J., Morris, A. D., Struthers, A. D., Palmer, C. N. A., Doney, A. S. F. & Lang, C. C. 2015 In : Circulation: Heart Failure.

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  66. Impact of left ventricular hypertrophy on survival in chronic obstructive pulmonary disease

    Short, P. M., Anderson, W. J., Elder, D. H. J., Struthers, A. D. & Lipworth, B. J. 2015 In : Lung. 9 p.

    Research output: Contribution to journalArticle

  67. Improving recruitment of older people to clinical trials: use of the cohort multiple randomised controlled trial design

    Clegg, A., Relton, C., Young, J. & Witham, M. 2015 In : Age and Ageing. 4 p.

    Research output: Contribution to journalComment/debate

  68. Kidney biopsy findings in primary Sjogren syndrome

    Kidder, D., Rutherford, E., Kipgen, D., Fleming, S., Geddes, C. & Stewart, G. A. 2015 In : Nephrology Dialysis Transplantation. 7 p.

    Research output: Contribution to journalArticle

  69. Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study

    Belch, J. & 20 others Shore, A. C., Colhoun, H. M., Natali, A., Palombo, C., Östling, G., Aizawa, K., Kennbäck, C., Casanova, F., Persson, M., Gates, P. E., Kahn, F., Looker, H. C., Adams, F., Pinnoli, S., Venturi, E., Morizzo, C., Goncalves, I., Ladenvall, C., Nilsson, J. & on behalf of the SUMMIT consortium 2015 In : Journal of Internal Medicine. 12 p.

    Research output: Contribution to journalArticle

  70. No strong relationship between components of the lectin pathway of complement and susceptibility to pulmonary tuberculosis

    Chalmers, J. D., Matsushita, M., Kilpatrick, D. C. & Hill, A. T. 2015 In : Inflammation. 7 p.

    Research output: Contribution to journalArticle

  71. Poster advertisements in practice waiting rooms to recruit patients to the Treatment In Morning vs. Evening (TIME) online study

    Rorie, D., Flynn, R., McConnachie, L., Mackenzie, I. S. & MacDonald, T. M. 2015 In : British Journal of Clinical Pharmacology. 2 p.

    Research output: Contribution to journalLetter

  72. Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes

    Looker, H. C., Colombo, M., Agakov, F., Zeller, T., Groop, L., Thorand, B., Palmer, C. N., Hamsten, A., de Faire, U., Nogoceke, E., Livingstone, S. J., Salomaa, V., Leander, K., Barbarini, N., Bellazzi, R., van Zuydam, N., McKeigue, P. M., Colhoun, H. M. & on behalf of the SUMMIT Investigators 2015 In : Diabetologia. 9 p.

    Research output: Contribution to journalArticle

  73. Psychoactive prescribing for older people-what difference does 15 years make?

    Hughes, L. D., Cochrane, L., McMurdo, M. E. T. & Guthrie, B. 2015 In : International Journal of Geriatric Psychiatry. 9 p.

    Research output: Contribution to journalArticle

  74. Assessment of spirometry and impulse oscillometry in relation to asthma control

    Manoharan, A., Anderson, W. J., Lipworth, J. & Lipworth, B. J. 17 Dec 2014 In : Lung.

    Research output: Contribution to journalArticle

  75. Substrate recognition by the cell surface palmitoyl transferase DHHC5

    Howie, J., Reilly, L., Fraser, N. J., Vlachaki Walker, J., Wypijewski, . K. J., Ashford, M. L. J., Calaghan, S., McClafferty, H., Tian, L., Shipston, M. J., Boguslavskyi, A., Shattock, M. J. & Fuller, W. 9 Dec 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 49, p. 17534-17539 6 p.

    Research output: Contribution to journalArticle

  76. Blood vessel segmentation and width estimation in ultra-wide field scanning laser ophthalmoscopy

    Pellegrini, E., Robertson, G., Trucco, E., MacGillivray, T. J., Lupascu, C., van Hemert, J., Williams, M. C., Newby, D. E., van Beek, E. J. R. & Houston, J. G. 1 Dec 2014 In : Biomedical Optics Express. 5, 12, p. 4329-4337 9 p.

    Research output: Contribution to journalArticle

  77. Salicylic acid: old and new implications for the treatment of type 2 diabetes?

    Rena, G. & Sakamoto, K. Dec 2014 In : Diabetology International. 5, 4, p. 212-218 7 p.

    Research output: Contribution to journalArticle

  78. The development and deployment of integrated electronic care records in a regional adult and paediatric cystic fibrosis unit

    Peckham, D., Etherington, C., White, H., Mehta, A., Shaw, N., Morton, A., Pollard, K., Lee, T., Brownlee, K., Taylor, J., Whitaker, P. & Conway, S. Dec 2014 In : Journal of Cystic Fibrosis. 13, 6, p. 681-686 6 p.

    Research output: Contribution to journalArticle

  79. The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

    Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J. Dec 2014 In : Clinical Science. 127, 11, p. 635-643 9 p.

    Research output: Contribution to journalArticle

  80. Update on the treatment of hepatitis C genotypes 2-6

    Paterson, J. C. M., Miller, M. H. & Dillon, J. F. Dec 2014 In : Current Opinion in Infectious Diseases. 27, 6, p. 540-544 5 p.

    Research output: Contribution to journalArticle

  81. Inactivating mutations in NPC1L1 and protection from coronary heart disease

    Stitziel, N. O. , Won, H-H. , Morrison, A. C. , Peloso, G. M. , Do, R. , Lange, L. A. , Fontanillas, P. , Gupta, N. , Duga, S. , Goel, A. , Farrall, M. , Saleheen, D. , Ferrario, P. , König, I. , Asselta, R. , Merlini, P. A. , Marziliano, N. , Notarangelo, M. F. , Schick, U. , Auer, P. & 57 others Assimes, T. L., Reilly, M., Wilensky, R., Rader, D. J., Hovingh, G. K., Meitinger, T., Kessler, T., Kastrati, A., Laugwitz, K-L., Siscovick, D., Rotter, J. I., Hazen, S. L., Tracy, R., Cresci, S., Spertus, J., Jackson, R., Schwartz, S. M., Natarajan, P., Crosby, J., Muzny, D., Ballantyne, C., Rich, S. S., O'Donnell, C. J., Abecasis, G., Sunyaev, S., Nickerson, D. A., Buring, J. E., Ridker, P. M., Chasman, D. I., Austin, E., Ye, Z., Kullo, I. J., Weeke, P. E., Shaffer, C. M., Bastarache, L. A., Denny, J. C., Roden, D. M., Palmer, C., Deloukas, P., Lin, D-Y., Tang, Z., Erdmann, J., Schunkert, H., Danesh, J., Marrugat, J., Elosua, R., Ardissino, D., McPherson, R., Watkins, H., Reiner, A. P., Wilson, J. G., Altshuler, D., Gibbs, R. A., Lander, E. S., Boerwinkle, E., Gabriel, S. & Kathiresan, S. 27 Nov 2014 In : New England Journal of Medicine. 371, 22, p. 2072-2082 11 p.

    Research output: Contribution to journalArticle

  82. Randomized double-blind placebo-controlled trial of perhexiline in heart failure with preserved ejection fraction syndrome

    Singh, S., Beadle, R., Cameron, D., Rudd, A., Bruce, M., Jagpal, B., Schwarz, K., Brindley, G., Mckiddie, F., Lang, C., Dawson, D. & Frenneaux, M. 1 Nov 2014 In : Future Cardiology. 10, 6, p. 693-698 6 p.

    Research output: Contribution to journalArticle

  83. Cardiovascular risk associated with sodium-containing medicines

    Wei, L., Mackenzie, I. S., MacDonald, T. M. & George, J. Nov 2014 In : Expert Opinion on Drug Safety. 13, 11, p. 1515-1523 9 p.

    Research output: Contribution to journalArticle

  84. Defining the role of common variation in the genomic and biological architecture of adult human height

    Morris, A. D. & 448 others Wood, A. R., Esko, T., Yang, J., Vedantam, S., Pers, T. H., Gustafsson, S., Chu, A. Y., Estrada, K., Luan, J., Kutalik, Z., Amin, N., Buchkovich, M. L., Croteau-Chonka, D. C., Day, F. R., Duan, Y., Fall, T., Fehrmann, R., Ferreira, T., Jackson, A. U., Karjalainen, J., Lo, K. S., Locke, A. E., Mägi, R., Mihailov, E., Porcu, E., Randall, J. C., Scherag, A., Vinkhuyzen, A. A. E., Westra, H-J., Winkler, T. W., Workalemahu, T., Zhao, J. H., Absher, D., Albrecht, E., Anderson, D., Baron, J., Beekman, M., Demirkan, A., Ehret, G. B., Feenstra, B., Feitosa, M. F., Fischer, K., Fraser, R. M., Goel, A., Gong, J., Justice, A. E., Kanoni, S., Kleber, M. E., Kristiansson, K., Lim, U., Lotay, V., Lui, J. C., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Nalls, M. A., Nyholt, D. R., Palmer, C. D., Pasko, D., Pechlivanis, S., Prokopenko, I., Ried, J. S., Ripke, S., Shungin, D., Stancáková, A., Strawbridge, R. J., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van Setten, J., Van Vliet-Ostaptchouk, J. V., Wang, Z., Yengo, L., Zhang, W., Afzal, U., Arnlöv, J., Arscott, G. M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A. J., Berne, C., Blüher, M., Bolton, J. L., Böttcher, Y., Boyd, H. A., Bruinenberg, M., Buckley, B. M., Buyske, S., Caspersen, I. H., Chines, P. S., Clarke, R., Claudi-Boehm, S., Cooper, M., Daw, E. W., De Jong, P. A., Deelen, J., Delgado, G., Denny, J. C., Dhonukshe-Rutten, R., Dimitriou, M., Doney, A. S. F., Dörr, M., Eklund, N., Eury, E., Folkersen, L., Garcia, M. E., Geller, F., Giedraitis, V., Go, A. S., Grallert, H., Grammer, T. B., Gräßler, J., Grönberg, H., de Groot, L. C. P. G. M., Groves, C. J., Haessler, J., Hall, P., Haller, T., Hallmans, G., Hannemann, A., Hartman, C. A., Hassinen, M., Hayward, C., Heard-Costa, N. L., Helmer, Q., Hemani, G., Henders, A. K., Hillege, H. L., Hlatky, M. A., Hoffmann, W., Hoffmann, P., Holmen, O., Houwing-Duistermaat, J. J., Illig, T., Isaacs, A., James, A. L., Jeff, J., Johansen, B., Johansson, Å., Jolley, J., Juliusdottir, T., Junttila, J., Kho, A. N., Kinnunen, L., Klopp, N., Kocher, T., Kratzer, W., Lichtner, P., Lind, L., Lindström, J., Lobbens, S., Lorentzon, M., Lu, Y., Lyssenko, V., Magnusson, P. K. E., Mahajan, A., Maillard, M., McArdle, W. L., McKenzie, C. A., McLachlan, S., McLaren, P. J., Menni, C., Merger, S., Milani, L., Moayyeri, A., Monda, K. L., Morken, M. A., Müller, G., Müller-Nurasyid, M., Musk, A. W., Narisu, N., Nauck, M., Nolte, I. M., Nöthen, M. M., Oozageer, L., Pilz, S., Rayner, N. W., Renstrom, F., Robertson, N. R., Rose, L. M., Roussel, R., Sanna, S., Scharnagl, H., Scholtens, S., Schumacher, F. R., Schunkert, H., Scott, R. A., Sehmi, J., Seufferlein, T., Shi, J., Silventoinen, K., Smit, J. H., Smith, A. V., Smolonska, J., Stanton, A. V., Stirrups, K., Stott, D. J., Stringham, H. 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T., Heath, A. C., Hengstenberg, C., Hicks, A. A., Hindorff, L. A., Hingorani, A. D., Hofman, A., Hovingh, G. K., Humphries, S. E., Hunt, S. C., Hypponen, E., Jacobs, K. B., Jarvelin, M-R., Jousilahti, P., Jula, A. M., Kaprio, J., Kastelein, J. J. P., Kayser, M., Kee, F., Keinanen-Kiukaanniemi, S. M., Kiemeney, L. A., Kooner, J. S., Kooperberg, C., Koskinen, S., Kovacs, P., Kraja, A. T., Kumari, M., Kuusisto, J., Lakka, T. A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lupoli, S., Madden, P. A. F., Männistö, S., Manunta, P., Marette, A., Matise, T. C., McKnight, B., Meitinger, T., Moll, F. L., Montgomery, G. W., Morris, A. P., Murray, J. C., Nelis, M., Ohlsson, C., Oldehinkel, A. J., Ong, K. K., Ouwehand, W. H., Pasterkamp, G., Peters, A., Pramstaller, P. P., Price, J. F., Qi, L., Raitakari, O. T., Rankinen, T., Rao, D. C., Rice, T. K., Ritchie, M., Rudan, I., Salomaa, V., Samani, N. J., Saramies, J., Sarzynski, M. A., Schwarz, P. E. H., Sebert, S., Sever, P., Shuldiner, A. R., Sinisalo, J., Steinthorsdottir, V., Stolk, R. P., Tardif, J-C., Tönjes, A., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M-C., Amouyel, P., Asselbergs, F. W., Assimes, T. L., Bochud, M., Boehm, B. O., Boerwinkle, E., Bottinger, E. P., Bouchard, C., Cauchi, S., Chambers, J. C., Chanock, S. J., Cooper, R. S., de Bakker, P. I. W., Dedoussis, G., Ferrucci, L., Franks, P. W., Froguel, P., Groop, L. C., Haiman, C. A., Hamsten, A., Hayes, M. G., Hui, J., Hunter, D. J., Hveem, K., Jukema, J. W., Kaplan, R. C., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Martin, N. G., März, W., Melbye, M., Moebus, S., Munroe, P. B., Njølstad, I., Oostra, B. A., Palmer, C. N. A., Pedersen, N. L., Perola, M., Pérusse, L., Peters, U., Powell, J. E., Power, C., Quertermous, T., Rauramaa, R., Reinmaa, E., Ridker, P. M., Rivadeneira, F., Rotter, J. I., Saaristo, T. E., Saleheen, D., Schlessinger, D., Slagboom, P. E., Snieder, H., Spector, T. D., Strauch, K., Stumvoll, M., Tuomilehto, J., Uusitupa, M., van der Harst, P., Völzke, H., Walker, M., Wareham, N. J., Watkins, H., Wichmann, H-E., Wilson, J. F., Zanen, P., Deloukas, P., Heid, I. M., Lindgren, C. M., Mohlke, K. L., Speliotes, E. K., Thorsteinsdottir, U., Barroso, I., Fox, C. S., North, K. E., Strachan, D. P., Beckmann, J. S., Berndt, S. I., Boehnke, M., Borecki, I. B., McCarthy, M. I., Metspalu, A., Stefansson, K., Uitterlinden, A. G., van Duijn, C. M., Franke, L., Willer, C. J., Price, A. L., Lettre, G., Loos, R. J. F., Weedon, M. N., Ingelsson, E., O'Connell, J. R., Abecasis, G. R., Chasman, D. I., Goddard, M. E., Visscher, P. M., Hirschhorn, J. N., Frayling, T. M., Electronic Medical Records and Genomics (eEMERGE) Consortium, MIGen Consortium, PAGE Consortium & LifeLines Cohort Study Nov 2014 In : Nature Genetics. 46, 11, p. 1173-1186 14 p.

    Research output: Contribution to journalArticle

  85. Heterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action in high fat-fed mice

    Kang, L., Dai, C., Lustig, M. E., Bonner, J. S., Mayes, W. H., Mokshagundam, S., James, F. D., Thompson, C. S., Lin, C-T., Perry, C. G. R., Anderson, E. J., Neufer, P. D., Wasserman, D. H. & Powers, A. C. Nov 2014 In : Diabetes. 63, 11, p. 3699-3710 12 p.

    Research output: Contribution to journalArticle

  86. Male fertility and infertility

    Ramalingam, M., Kini, S. & Mahmood, T. Nov 2014 In : Obstetrics, Gynaecology and Reproductive Medicine. 24, 11, p. 326-332 7 p.

    Research output: Contribution to journalArticle

  87. Quantifying the real life risk profile of inhaled corticosteroids in COPD by record linkage analysis

    Flynn, R. W., MacDonald, T. M., Hapca, A., MacKenzie, I. S. & Schembri, S. Nov 2014 In : Respiratory Research. 15, 8 p., 141

    Research output: Contribution to journalArticle

  88. Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation

    De Stefano, D. , Villella, V. R. , Esposito, S. , Tosco, A. , Sepe, A. , De Gregorio, F. , Salvadori, L. , Grassia, R. , Leone, C. A. , De Rosa, G. , Maiuri, M. C. , Pettoello-Mantovani, M. , Guido, S. , Bossi, A. , Zolin, A. , Venerando, A. , Pinna, L. A. , Mehta, A. , Bona, G. , Kroemer, G. & 2 others Maiuri, L. & Raia, V. Nov 2014 In : Autophagy. 10, 11, p. 2053-2074 22 p.

    Research output: Contribution to journalArticle

  89. Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen

    Mohammed Abdul, K. S., Jovanovic, S., Sukhodub, A., Du, Q. & Jovanovic, A. Nov 2014 In : Biochimica et Biophysica Acta. Molecular Cell Research. 1843, 11, p. 2424-2431 8 p.

    Research output: Contribution to journalArticle

  90. Uptake of hepatitis C specialist services and treatment following diagnosis by dried blood spot in Scotland

    McAllister, G., Innes, H., Mcleod, A., Dillon, J. F., Hayes, P. C., Fox, R., Barclay, S. T., Templeton, K., Aitken, C., Gunson, R., Goldberg, D. & Hutchinson, S. J. Nov 2014 In : Journal of Clinical Virology . 61, 3, p. 359-364 6 p.

    Research output: Contribution to journalArticle

  91. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

    Morris, A. & 103 others Postmus, I., Trompet, S., Deshmukh, H. A., Barnes, M. R., Li, X., Warren, H. R., Chasman, D. I., Zhou, K., Arsenault, B. J., Donnelly, L. A., Wiggins, K. L., Avery, C. L., Griffin, P., Feng, Q., Taylor, K. D., Li, G., Evans, D. S., Smith, A. V., de Keyser, C. E., Johnson, A. D., de Craen, A. J. M., Stott, D. J., Buckley, B. M., Ford, I., Westendorp, R. G. J., Eline Slagboom, P., Sattar, N., Munroe, P. B., Sever, P., Poulter, N., Stanton, A., Shields, D. C., O'Brien, E., Shaw-Hawkins, S., Ida Chen, Y-D., Nickerson, D. A., Smith, J. D., Pierre Dubé, M., Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, J. J. P., McKeigue, P. M., Betteridge, J., Neil, A., Durrington, P. N., Doney, A., Carr, F., McCarthy, M. I., Groop, L., Ahlqvist, E., Bis, J. C., Rice, K., Smith, N. L., Lumley, T., Whitsel, E. A., Stürmer, T., Boerwinkle, E., Ngwa, J. S., O'Donnell, C. J., Vasan, R. S., Wei, W-Q., Wilke, R. A., Liu, C-T., Sun, F., Guo, X., Heckbert, S. R., Post, W., Sotoodehnia, N., Arnold, A. M., Stafford, J. M., Ding, J., Herrington, D. M., Kritchevsky, S. B., Eiriksdottir, G., Launer, L. J., Harris, T. B., Chu, A. Y., Giulianini, F., MacFadyen, J. G., Barratt, B. J., Nyberg, F., Stricker, B. H., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Emilsson, V., Franco, O. H., Ridker, P. M., Gudnason, V., Liu, Y., Denny, J. C., Ballantyne, C. M., Rotter, J. I., Adrienne Cupples, L., Psaty, B. M., Palmer, C. N. A., Tardif, J-C., Colhoun, H. M., Hitman, G., Krauss, R. M., Wouter Jukema, J., Caulfield, M. J. & Welcome Trust Case Control Consortium 28 Oct 2014 In : Nature Communications. 5, 10 p., 5068

    Research output: Contribution to journalArticle

  92. Cardiac hypertrophy in mice expressing unphosphorylatable phospholemman

    Boguslavskyi, A., Pavlovic, D., Aughton, K., Clark, J. E., Howie, J., Fuller, W. & Shattock, M. J. 1 Oct 2014 In : Cardiovascular Research. 104, 1, p. 72-82 11 p.

    Research output: Contribution to journalArticle

  93. Phenotype standardisation of angioedema in the head and neck region caused by agents acting on the angiotensin system

    Wadelius, M., Marshall, S. E., Islander, G., Nordang, L., Karawajczyk, M., Yue, Q-Y., Terreehorst, I., Baranova, E. V., Hugosson, S., Sköldefors, K., Pirmohamed, M., Maitland van der Zee, A-H., Alfirevic, A., Hallberg, P. & Palmer, C. N. A. Oct 2014 In : Clinical Pharmacology & Therapeutics. 96, 4, p. 477-481

    Research output: Contribution to journalScientific review

  94. Phenotype standardization for statin-induced myotoxicity

    Alfirevic, A., Neely, D., Armitage, J., Chinoy, H., Cooper, R. G., Laaksonen, R., Carr, D. F., Bloch, K. M., Fahy, J., Hanson, A., Yue, Q. Y., Wadelius, M., Maitland-van Der Zee, A. H., Voora, D., Psaty, B. M., Palmer, C. N. A. & Pirmohamed, M. Oct 2014 In : Clinical Pharmacology & Therapeutics. 96, 4, p. 470-476 7 p.

    Research output: Contribution to journalArticle

  95. The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

    Manoharan, A., Lipworth, B., Craig, E. & Jackson, C. Oct 2014 In : Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

    Research output: Contribution to journalArticle

  96. The serum proteome of nonalcoholic fatty liver disease: a multimodal approach to discovery of biomarkers of nonalcoholic steatohepatitis

    Miller, M. H., Walsh, S. V., Atirh, A., Huang, J. T-J., Ferguson, M. A. J. & Dillon, J. F. Oct 2014 In : Journal of Gastroenterology and Hepatology. 29, 10, p. 1839-1847 9 p.

    Research output: Contribution to journalArticle

  97. Impact of age and gender on the prevalence and prognostic importance of the metabolic syndrome and its components in Europeans: the MORGAM Prospective Cohort Project

    Vishram, J. K. K. , Borglykke, A. , Andreasen, A. H. , Jeppesen, J. , Ibsen, H. , Jørgensen, T. , Palmieri, L. , Giampaoli, S. , Donfrancesco, C. , Kee, F. , Mancia, G. , Cesana, G. , Kuulasmaa, K. , Salomaa, V. , Sans, S. , Ferrieres, J. , Dallongeville, J. , Söderberg, S. , Arveiler, D. , Wagner, A. & 4 others Tunstall-Pedoe, H., Drygas, W., Olsen, M. H. & on behalf of the MORGAM Project 22 Sep 2014 In : PLoS ONE. 9, 9, 12 p., e107294

    Research output: Contribution to journalArticle

  98. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

    Springelkamp, H. , Höhn, R. , Mishra, A. , Hysi, P. G. , Khor, C-C. , Loomis, S. J. , Bailey, J. N. C. , Gibson, J. , Thorleifsson, G. , Janssen, S. F. , Luo, X. , Ramdas, W. D. , Vithana, E. , Nongpiur, M. E. , Montgomery, G. W. , Xu, L. , Mountain, J. E. , Gharahkhani, P. , Lu, Y. , Amin, N. & 61 others Karssen, L. C., Sim, K-S., van Leeuwen, E. M., Iglesias, A. I., Verhoeven, V. J. M., Hauser, M. A., Loon, S-C., Despriet, D. D. G., Nag, A., Venturini, C., Sanfilippo, P. G., Schillert, A., Kang, J. H., Landers, J., Jonasson, F., Cree, A. J., van Koolwijk, L. M. E., Rivadeneira, F., Souzeau, E., Jonsson, V., Menon, G., Weinreb, R. N., de Jong, P. T. V. M., Oostra, B. A., Uitterlinden, A. G., Hofman, A., Ennis, S., Thorsteinsdottir, U., Burdon, K. P., Spector, T. D., Mirshahi, A., Saw, S-M., Vingerling, J. R., Teo, Y-Y., Haines, J. L., Wolfs, R. C. W., Lemij, H. G., Tai, E-S., Jansonius, N. M., Jonas, J. B., Cheng, C-Y., Aung, T., Viswanathan, A. C., Klaver, C. C. W., Craig, J. E., Macgregor, S., Mackey, D. A., Lotery, A. J., Stefansson, K., Bergen, A. A. B., Young, T. L., Wiggs, J. L., Pfeiffer, N., Wong, T-Y., Pasquale, L. R., Hewitt, A. W., van Duijn, C. M., Hammond, C. J., Blue Mountains Eye Study—GWAS group, NEIGHBORHOOD Consortium & Wellcome Trust Case Control Consortium 2 (WTCCC2) 22 Sep 2014 In : Nature Communications. 5, 7 p., 4883

    Research output: Contribution to journalArticle

  99. High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis

    Chin, C. W. L., Shah, A. S. V., McAllister, D. A., Cowell, S. J., Alam, S., Langrish, J. P., Strachan, F. E., Hunter, A. L., Maria Choy, A., Lang, C. C., Walker, S., Boon, N. A., Newby, D. E., Mills, N. L. & Dweck, M. R. 7 Sep 2014 In : European Heart Journal. 35, 34, p. 2312-2321 10 p.

    Research output: Contribution to journalArticle

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