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Division of Cardiovascular & Diabetes Medicine

  1. Defining drug response for stratified medicine

    Lonergan, M., Senn, S. J., McNamee, C., Daly, A. K., Sutton, R., Hattersley, A., Pearson, E. & Pirmohamed, M. 3 Nov 2016 In : Drug Discovery Today. 7 p.

    Research output: Contribution to journalReview article

  2. Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013

    Read, S. H., Kerssens, J. J., McAllister, D. A., Colhoun, H. M., Fischbacher, C. M., Lindsay, R. S., McCrimmon, R. J., McKnight, J. A., Petrie, J. R., Sattar, N., Wild, S. H. & On behalf of the Scottish Diabetes Research Network Epidemiology Group Oct 2016 In : Diabetologia. 59, 10, p. 2106-2113 8 p.

    Research output: Contribution to journalArticle

  3. tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy

    Yew, T. W., McCreight, L., Colclough, K., Ellard, S. & Pearson, E. R. 17 Aug 2016 In : Diabetic Medicine. 33, 9, p. e21-e25 5 p.

    Research output: Contribution to journalArticle

  4. Acute risk factors in fatal opioid overdoses as a result of hypoxia and cardiotoxicity. A systematic review and critical appraisal

    Baldacchino, A., Tolomeo, S., Khan, F., Humphris, G. & Carrà, G. Aug 2016 In : Heroin Addiction and Related Clinical Problems. 18, 4, p. 33-42 10 p.

    Research output: Contribution to journalReview article

  5. Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

    Cameron, A., Logie, L., Patel, K., Bacon, S., Forteath, C., Harthill, J., Roberts, A., Sutherland, C., Stewart, D., Viollet, B., Sakamoto, K., McDougall, G., Foretz, M. & Rena, G. Aug 2016 In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1862, 8, p. 1412-1422 11 p.

    Research output: Contribution to journalArticle

  6. Transcutaneous Electrical Nerve Stimulation improves walking performance in patients with intermittent claudication

    Seenan, C., McSwiggan, S., Roche, P. A., Tan, C-W., Mercer, T. & Belch, J. J. F. Jul 2016 In : European Journal of Cardiovascular Nursing. 31, 4, p. 323-330 8 p.

    Research output: Contribution to journalArticle

  7. Common Creatine Kinase gene mutation results in falsely reassuring CK levels in muscle disorders

    Wallace, B., Siddiqui, M. K., Palmer, C. N. A. & George, J. 1 Jun 2016 In : QJM : an International Journal of Medicine. 109, 6, p. 413-414 3 p.

    Research output: Contribution to journalArticle

  8. Can antioxidant-rich blackcurrant juice drink consumption improve photoprotection against ultraviolet radiation?

    Ray, S., Belch, J. J., Craigie, A. M., Khan, F., Kennedy, G., Hill, A., Barton, K. L., Dawe, R. S. & Ibbotson, S. H. May 2016 In : British Journal of Dermatology. 174, 5, p. 1101-1103 3 p.

    Research output: Contribution to journalLetter

  9. Spironolactone for people aged 70 or over with osteoarthritic knee pain: a proof-of-concept trial

    McMurdo, M. E. T., Sumukadas, D., Donnan, P. T., Cvoro, V., Rauchhaus, P., Argo, I., Waldie, H., Littleford, R., Struthers, A. D. & Witham, M. D. May 2016 In : Arthritis Care & Research. 68, 5, p. 716-721 6 p.

    Research output: Contribution to journalArticle

  10. Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

    Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P. 1 Apr 2016 In : Psychoneuroendocrinology. 66, p. 214-220 7 p.

    Research output: Contribution to journalArticle

  11. Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

    Manoharan, A., Morrison, A. E. & Lipworth, B. Apr 2016 In : Lung. 194, 2, p. 259-266 8 p.

    Research output: Contribution to journalArticle

  12. Efficacy of the ulnar-basilic arteriovenous fistula for hemodialysis: a systematic review

    Al Shakarchi, J., Khawaja, A., Cassidy, D., Houston, J. G. & Inston, N. Apr 2016 In : Annals of Vascular Surgery. 32, p. 1-4 4 p.

    Research output: Contribution to journalArticle

  13. Is Gly16Arg β2 Receptor Polymorphism Related to Impulse Oscillometry in a Real-Life Asthma Clinic Setting?

    Jabbal, S., Manoharan, A., Lipworth, J., Anderson, W., Short, P. & Lipworth, B. Apr 2016 In : Lung. 194, 2, p. 267-271 5 p.

    Research output: Contribution to journalArticle

  14. The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large ‘real world’ cohort

    Wang, H., Innes, H., Hutchinson, S. J., Goldberg, D. J., Allen, S., Barclay, S. T., Bramley, P., Fox, R., Fraser, A., Hayes, P. C., Kennedy, N., Mills, P. R. & Dillon, J. F. Apr 2016 In : European Journal of Gastroenterology & Hepatology. 28, 4, p. 398-404 7 p.

    Research output: Contribution to journalArticle

  15. S-palmitoylation and the regulation of NCX1

    Fuller, W., Reilly, L. & Hilgemann, D. W. 3 Mar 2016 In : Channels. 10, 2, p. 75-77 3 p.

    Research output: Contribution to journalArticle

  16. Effects of formoterol or salmeterol on impulse oscillometry in persistent asthma

    Manoharan, A., von Wilamowitz-Moellendorff, A., Morrison, A. & Lipworth, B. J. Mar 2016 In : Journal of Allergy and Clinical Immunology. 137, 3, p. 727-733.e1 8 p.

    Research output: Contribution to journalArticle

  17. Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance

    Connelly, P. J., Smith, N., Chadwick, R., Exley, A. R., Shneerson, J. M. & Pearson, E. R. Mar 2016 In : Diabetic Medicine. 33, 3, p. 371-375 5 p.

    Research output: Contribution to journalArticle

  18. Protein phosphatase 1c associated with the cardiac sodium calcium exchanger1 regulates its activity by dephosphorylating serine 68 phosphorylated phospholemman

    Lubelwana Hafver, T., Hodne, K., Wanichawan, P., Aronsen, J. M., Dalhus, B., Lunde, P. K., Lunde, M., Martinsen, M., Enger, U. H., Fuller, W., Sjaastad, I., Louch, W. E., Sejersted, O. M. & Carlson, C. R. 26 Feb 2016 In : Journal of Biological Chemistry. 291, 9, p. 4561-4579 8 p.

    Research output: Contribution to journalArticle

  19. Educational class inequalities in the incidence of coronary heart disease in Europe

    Veronesi, G. , Ferrario, M. M. , Kuulasmaa, K. , Bobak, M. , Chambless, L. E. , Salomaa, V. , Soderberg, S. , Pajak, A. , Jørgensen, T. , Amouyel, P. , Arveiler, D. , Drygas, W. , Ferrieres, J. , Giampaoli, S. , Kee, F. , Iacoviello, L. , Malyutina, S. , Peters, A. , Tamosiunas, A. & 2 others Tunstall-Pedoe, H. & Cesana, G. 5 Feb 2016 In : Heart. 102, 12, p. 958-965 8 p.

    Research output: Contribution to journalArticle

  20. Of mice and men-the curious tale of β blockers in asthma

    Lipworth, B. & Jabbal, S. 2 Feb 2016 In : The Lancet Respiratory Medicine. 4, 2, p. 89-91 3 p.

    Research output: Contribution to journalComment/debate

  21. Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

    Brown, M. J., Williams, B., Morant, S. V., Webb, D. J., Caulfield, M. J., Cruickshank, J. K., Ford, I., McInnes, G., Sever, P., Salsbury, J., Mackenzie, I. S., Padmanabhan, S., MacDonald, T. M. & for the British Hypertension Society's Prevention, Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group Feb 2016 In : The Lancet: Diabetes and Endocrinology. 4, 2, p. 136-147 12 p.

    Research output: Contribution to journalArticle

  22. Haemodynamics and flow modification stents for peripheral arterial disease: a review

    Kokkalis, E., Aristokleous, N. & Houston, J. G. Feb 2016 In : Annals of Biomedical Engineering. 44, 2, p. 466-476 11 p.

    Research output: Contribution to journalArticle

  23. From mouse to man: predicting biased effects of beta-blockers in asthma

    Lipworth, B. J., Anderson, W. J. & Short, P. M. Jan 2016 In : British Journal of Pharmacology. 173, 1, p. 248-249 2 p.

    Research output: Contribution to journalLetter

  24. Inhaled corticosteroid dose-response on blood eosinophils in asthma

    Lipworth, B., Jabbal, S., Manoharan, A., Anderson, W. & Short, P. Jan 2016 In : The Lancet Respiratory Medicine. 4, 1, p. e1

    Research output: Contribution to journalLetter

  25. Psychoactive prescribing for older people-what difference does 15 years make?

    Hughes, L. D., Cochrane, L., McMurdo, M. E. T. & Guthrie, B. Jan 2016 In : International Journal of Geriatric Psychiatry. 31, 1, p. 49-57 9 p.

    Research output: Contribution to journalArticle

  26. The EMBARC European Bronchiectasis Registry: protocol for an international observational study

    Chalmers, J. D. , Aliberti, S. , Polverino, E. , Vendrell, M. , Crichton, M. , Loebinger, M. , Dimakou, K. , Clifton, I. , van der Eerden, M. , Rohde, G. , Murris-Espin, M. , Masefield, S. , Gerada, E. , Shteinberg, M. , Ringshausen, F. , Haworth, C. , Boersma, W. , Rademacher, J. , Hill, A. T. & 18 others Aksamit, T., O'Donnell, A., Morgan, L., Milenkovic, B., Tramma, L., Neves, J., Menendez, R., Paggiaro, P., Botnaru, V., Skrgat, S., Wilson, R., Goeminne, P., De Soyza, A., Welte, T., Torres, A., Elborn, J. S., Blasi, F. & on behalf of EMBARC Jan 2016 In : ERJ Open Research. 2, 1, p. 1-9 9 p., 00081-2015

    Research output: Contribution to journalArticle

  27. Initiation of insulin adjustment for carbohydrate at onset of diabetes in children using a home‐based education programme with a bolus calculator

    Thom, H., Greene, S., Alexander, V., Ramsay, V., Bluff, S., Mackenzie, L., Sturrock, C. & Conway, N. T. 2016 In : Practical Diabetes. 33, 1, p. 19-22a 5 p.

    Research output: Contribution to journalArticle

  28. Whole body cardiovascular MRI for the comparison of atherosclerotic burden and cardiac remodelling in healthy South Asian and European adults

    Weir-McCall, J., Cassidy, D. B., Belch, J. J. F., Gandy, S. J., Houston, J. G., Lambert, M. A., Littleford, R. C., Rowland, J., Struthers, A. D. & Khan, F. 2016 In : British Journal of Radiology. 89, 1065, 8 p., 20150887

    Research output: Contribution to journalArticle

  29. The copper binding properties of metformin - QCM-D, XPS and nanobead agglomeration

    Quan, X., Uddin, R., Heiskanen, A., Parmvi, M., Nilson, K., Donolato, M., Hansen, M. F., Rena, G. & Boisen, A. 18 Dec 2015 In : Chemical Communications. 51, 97, p. 17313-17316 4 p.

    Research output: Contribution to journalArticle

  30. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    Artigas, M. S. , Wain, L. V. , Miller, S. , Kheirallah, A. K. , Huffman, J. E. , Ntalla, I. , Shrine, N. , Obeidat, M. , Trochet, H. , McArdle, W. L. , Alves, A. C. , Hui, J. , Zhao, J. H. , Joshi, P. K. , Teumer, A. , Albrecht, E. , Imboden, M. , Rawal, R. , Lopez, L. M. & 79 others Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L. P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C. A., Campbell, H., Gieger, C., Gläser, S., González, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A. L., Heliövaara, M., Henderson, J., Hocking, L., Horikoshi, M., Hutri-Kähönen, N., Ingelsson, E., Johansson, Å., Kemp, J. P., Kolcic, I., Kumar, A., Lind, L., Melén, E., Musk, A. W., Navarro, P., Nickle, D. C., Padmanabhan, S., Raitakari, O. T., Ried, J. S., Ripatti, S., Schulz, H., Scott, R. A., Sin, D. D., Starr, J. M., Viñuela, A., Völzke, H., Wild, S. H., Wright, A. F., Zemunik, T., Jarvis, D. L., Spector, T. D., Evans, D. M., Lehtimäki, T., Vitart, V., Kähönen, M., Gyllensten, U., Rudan, I., Deary, I. J., Karrasch, S., Probst-Hensch, N. M., Heinrich, J., Stubbe, B., Wilson, J. F., Wareham, N. J., James, A. L., Morris, A. P., Jarvelin, M. R., Hayward, C., Sayers, I., Strachan, D. P., Hall, I. P., Tobin, M. D., Deloukas, P., Hansell, A. L., Hubbard, R., Jackson, V. E., Marchini, J., Pavord, I., Thomson, N. C. & Zeggini, E. 4 Dec 2015 In : Nature Communications. 6, 12 p., 89658

    Research output: Contribution to journalArticle

  31. mHealth applications for diabetes: user preference and implications for app development

    Conway, N., Campbell, I., Forbes, P., Cunningham, S. & Wake, D. 3 Dec 2015 In : Health Informatics Journal. 10 p.

    Research output: Contribution to journalArticle

  32. Decision support for diabetes: implementation and evaluation of the EBMeDS project within NHS Scotland

    Conway, N., Cunningham, S., Forbes, P., Shaik, F., Emslie-Smith, A., Wales, A. & Wake, D. 1 Dec 2015

    Research output: Contribution to conferencePoster

  33. Health state utilities associated with attributes of treatments for hepatitis C

    Matza, L. S., Sapra, S. J., Dillon, J. F., Kalsekar, A., Davies, E. W., Devine, M. K., Jordan, J. B., Landrian, A. S. & Feeny, D. H. 1 Dec 2015 In : European Journal of Health Economics. 16, 9, p. 1005-1018 14 p.

    Research output: Contribution to journalArticle

  34. mHealth applications for diabetes – user preference and implications for app development

    Conway, N., Campbell, I., Forbes, P., Cunningham, S. & Wake, D. 1 Dec 2015

    Research output: Contribution to conferencePoster

  35. Clinical practice guidelines and the older patient: wake up call for geriatricians

    Vilches-Moraga, A., Martinez-Velilla, N., Cherubini, A., McMurdo, M., Singh, I. & Pattison, T. Dec 2015 In : European Geriatric Medicine. 6, 6, p. 513-514 2 p.

    Research output: Contribution to journalEditorial

  36. Etiology of non-cystic fibrosis bronchiectasis in adults and its correlation to disease severity

    Lonni, S., Chalmers, J. D., Goeminne, P. C., McDonnell, M. J., Dimakou, K., De Soyza, A., Polverino, E., Van De Kerkhove, C., Rutherford, R., Davison, J., Rosales, E., Pesci, A., Restrepo, M. I., Torres, A. & Aliberti, S. Dec 2015 In : Annals of the American Thoracic Society. 12, 12, p. 1764-1770 7 p.

    Research output: Contribution to journalArticle

  37. Implementation of the Lancet Standing Commission on liver disease in the UK

    Williams, R. , Ashton, K. , Aspinall, R. , Bellis, M. A. , Bosanquet, J. , Cramp, M. E. , Day, N. , Dhawan, A. , Dillon, J. , Dyson, J. , Ferguson, J. , Foster, G. , Gilmore, I. , Glynn, M. , Guthrie, J. A. , Hudson, M. , Kelly, D. , Langford, A. , Newsome, P. & 6 others O'Grady, J., Pryke, R., Ryder, S., Samyn, M., Sheron, N. & Verne, J. 21 Nov 2015 In : Lancet. 386, 10008, p. 2098-2111 14 p.

    Research output: Contribution to journalArticle

  38. Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

    Williams, B., MacDonald, T. M., Morant, S., Webb, D. J., Sever, P., McInnes, G., Ford, I., Cruickshank, J. K., Caulfield, M. J., Salsbury, J., Mackenzie, I., Padmanabhan, S., Brown, M. J. & or The British Hypertension Society's PATHWAY Studies Group 21 Nov 2015 In : Lancet. 386, 10008, p. 2059-2068 10 p.

    Research output: Contribution to journalArticle

  39. Thiel soft embalmed Porcine Kidney Perfusion Model for focused ultrasound therapy

    Wang, J., Xiao, X., Duncan, R., Karakitsios, I., Huang, Z., McLeod, H. & Melzer, A. 13 Nov 2015 2015 IEEE International Ultrasonics Symposium, IUS 2015. Institute of Electrical and Electronics Engineers, 7329408

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  40. Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival: observational cohort study

    Bell, S., Dekker, F. W., Vadiveloo, T., Marwick, C., Deshmukh, H., Donnan, P. T. & Van Diepen, M. 11 Nov 2015 In : BMJ. 351, 9 p., h5639

    Research output: Contribution to journalArticle

  41. Early cannulation grafts for haemodialysis: a systematic review

    Al Shakarchi, J., Houston, G. & Inston, N. 6 Nov 2015 In : Journal of Vascular Access. 16, 6, p. 493-497 5 p.

    Research output: Contribution to journalArticle

  42. Strategies for the treatment of Hepatitis C in an era of interferon-free therapies: what public health outcomes do we value most?

    Innes, H., Goldberg, D., Dillon, J. & Hutchinson, S. J. 1 Nov 2015 In : Gut. 64, 11, p. 1800-1809 10 p.

    Research output: Contribution to journalArticle

  43. Association between kidney function, rehabilitation outcome, and survival in older patients discharged from inpatient rehabilitation

    Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D. Nov 2015 In : American Journal of Kidney Diseases. 66, 5, p. 768-774 7 p.

    Research output: Contribution to journalArticle

  44. Association between retinal vasculature and muscle mass in older people

    Sumukadas, D., McMurdo, M., Pieretti, I., Ballerini, L., Price, R., Wilson, P., Doney, A., Leese, G. & Trucco, E. Nov 2015 In : Archives of Gerontology and Geriatrics. 61, 3, p. 425-428 4 p.

    Research output: Contribution to journalArticle

  45. Early diagnosis improves outcomes in hepatitis C

    Miller, M. H. & Dillon, J. F. Nov 2015 In : Practitioner. 259, 1787, p. 25-27 3 p.

    Research output: Contribution to journalArticle

  46. Exaggerated exercise blood pressure response and future cardiovascular disease

    Tzemos, N., Lim, P. O., Mackenzie, I. S. & Macdonald, T. M. Nov 2015 In : Journal of Clinical Hypertension . 17, 11, p. 837-844 8 p.

    Research output: Contribution to journalArticle

  47. Expansion of HCV treatment access to people who have injected drugs through effective translation of research into public health policy: Scotland's experience

    Hutchinson, S. J., Dillon, J. F., Fox, R., McDonald, S. A., Innes, H. A., Weir, A., McLeod, A., Aspinall, E. J., Palmateer, N. E., Taylor, A., Munro, A., Valerio, H., Brown, G. & Goldberg, D. J. Nov 2015 In : International Journal of Drug Policy. 26, 11, p. 1041-1049 9 p.

    Research output: Contribution to journalArticle

  48. The role of pulmonary arterial stiffness in COPD

    Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G. Nov 2015 In : Respiratory Medicine. 109, 11, p. 1381-1390 10 p.

    Research output: Contribution to journalReview article

  49. Effects of education to facilitate knowledge about chronic pain for adults: a systematic review with meta-analysis

    Geneen, L. J., Martin, D. J., Adams, N., Clarke, C., Dunbar, M., Jones, D., McNamee, P., Schofield, P. & Smith, B. H. 1 Oct 2015 In : Systematic Reviews. 4, 21 p., 132

    Research output: Contribution to journalArticle

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