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  1. Upregulation of cardioprotective SUR2A by sub-hypoxic drop in oxygen

    Mohammed Abdul, K. S., Jovanović, S., Sukhodub, A., Du, Q. & Jovanović, A. Nov 2014 In : Biochimica et Biophysica Acta. Molecular Cell Research. 1843, 11, p. 2424-2431 8 p.

    Research output: Contribution to journalArticle

  2. ACE inhibitors, statins and thiazides: no association with change in grip strength among community dwelling older men and women from the Hertfordshire Cohort Study

    Witham, M. D., Syddall, H. E., Dennison, E., Cooper, C., McMurdo, M. E. T. & Sayer, A. A. Sep 2014 In : Age and Ageing. 43, 5, p. 661-666 6 p.

    Research output: Contribution to journalArticle

  3. Bronchiectasis trials: losing the battle but winning the war?

    Chalmers, J. D. Sep 2014 In : The Lancet Respiratory Medicine. 2, 9, p. 679-681 3 p.

    Research output: Contribution to journalArticle

  4. Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains

    Kneuper, H., Cao, Z. P., Twomey, K. B., Zoltner, M., Jäger, F., Cargill, J. S., Chalmers, J., van der Kooi-Pol, M. M., van Dijl, J. M., Ryan, R. P., Hunter, W. N. & Palmer, T. Sep 2014 In : Molecular Microbiology. 93, 5, p. 928-943 15 p.

    Research output: Contribution to journalArticle

  5. The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

    Patel, K., Foretz, M., Marion, A., Campbell, D. G., Gourlay, R., Boudaba, N., Tournier, E., Titchenell, P., Peggie, M., Deak, M., Wan, M., Kaestner, K. H., Göransson, O., Viollet, B., Gray, N. S., Birnbaum, M. J., Sutherland, C. & Sakamoto, K. 4 Aug 2014 In : Nature Communications. 5, 4535

    Research output: Contribution to journalArticle

  6. Retinal imaging as a source of biomarkers for diagnosis, characterization and prognosis of chronic illness or long-term conditions

    MacGillivray, T. J., Trucco, E., Cameron, J. R., Dhillon, B., Houston, J. G. & van Beek, E. J. R. Aug 2014 In : British Journal of Radiology. 87, 1040, 16 p.20130832

    Research output: Contribution to journalArticle

  7. The contribution of educational class in improving accuracy of cardiovascular risk prediction across European regions: the MORGAM Project Cohort Component

    Ferrario, M. M. , Veronesi, G. , Chambless, L. E. , Tunstall-Pedoe, H. , Kuulasmaa, K. , Salomaa, V. , Borglykke, A. , Hart, N. , Söderberg, S. , Cesana, G. , Jørgensen, T. , Agger, C. , Juolevi, A. , Vartiainen, E. , Jousilahti, P. , Cepaitis, Z. , Haukijärvi, A. , Joseph, B. , Kulathinal, S. , Niemelä, M. & 74 others Saarela, O., Ducimetière, P., Bingham, A., Arveiler, D., Haas, B., Wagner, A., Ferrières, J., Ruidavets, J-B., Bongard, V., Amouyel, P., Montaye, M., Dallongeville, J., Döring, A., Wichmann, E., Fornari, C., Sega, R., Mancia, G., Facchetti, R., Vanuzzo, D., Pilotto, L., Picco, F., Mattiussi, F., Gigante, S., Tamosiunas, A., Domarkiene, S., Rastenyte, D., Bernotiene, G., Radisauskas, R., Baceviciene, M., Luksiene, D., Malinauskiene, V., Bernotaite, L., Pajak, A., Kawalec, E., Broda, G., Kurjata, P., Rywik, S. L., Polakowska, M., Pytlak, A., Nikitin, Y., Malyutina, S., Gafarov, V., Feigin, V., Siminova, G., Voevoda, M., Vinogradova, T., Nasonova, N., Veriovkin, E., Eliasson, M., Stegmayr, B., Eriksson, M., Asplund, K., Kee, F., Evans, A., Yarnell, J., Gardner, E., Woodward, M., Evans, A., Cashman, S., Evans, A., Blankenberg, S., Kee, F., Palotie, A., Perola, M., Peters, A., Salomaa, V., Tregouet, D., Asplund, K., Cambien, F., Tiret, L., Peltonen, L., Shields, D., Stegmayr, B. & Wiklund, P-G. Aug 2014 In : Heart. 100, 15, p. 1179-1187 9 p.

    Research output: Contribution to journalArticle

  8. Proteomic and genomic studies of non-alcoholic fatty liver disease - clues in the pathogenesis

    Lim, J. W., Dillon, J. & Miller, M. 14 Jul 2014 In : World Journal of Gastroenterology . 20, 26, p. 8325-8340 16 p.

    Research output: Contribution to journalArticle

  9. CFTR functional measurements in human models for diagnosis, prognosis and personalized therapy: report on the pre-conference meeting to the 11th ECFS Basic Science Conference, Malta, 26-29 March 2014

    Beekman, J. M., Sermet-Gaudelus, I., de Boeck, K., Gonska, T., Derichs, N., Mall, M. A., Mehta, A., Martin, U., Drumm, M. & Amaral, M. D. Jul 2014 In : Journal of Cystic Fibrosis. 13, 4, p. 363-372 10 p.

    Research output: Contribution to journalArticle

  10. Intergenerational transmission of postpartum haemorrhage risk: analysis of two Scottish birth cohorts

    Sharp, G. C., Saunders, P. T. K., Greene, S. A., Morris, A. D. & Norman, J. E. Jul 2014 In : American Journal of Obstetrics and Gynecology. 211, 1, p. 51.e1-51.e7 7 p.

    Research output: Contribution to journalArticle

  11. Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?

    Harrison, M. T., Short, P., Williamson, P. A., Singanayagam, A., Chalmers, J. D. & Schembri, S. Jul 2014 In : Thorax. 69, 7, p. 609-615 7 p.

    Research output: Contribution to journalArticle

  12. Wireless MR tracking of interventional devices using phase-field dithering and projection reconstruction

    Rube, M. A., Holbrook, A. B., Cox, B. F., Houston, J. G. & Melzer, A. Jul 2014 In : Magnetic Resonance Imaging. 32, 6, p. 693-701 9 p.

    Research output: Contribution to journalArticle

  13. Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

    Norsworthy, P. J., Vandrovcova, J., Thomas, E. R. A., Campbell, A., Kerr, S. M., Biggs, J., Game, L., Soutar, A. K., Smith, B. H., Dominiczak, A. F., Porteous, D. J., Morris, A. D., Generation Scotland & Aitman, T. J. 23 Jun 2014 In : BMC Medical Genetics. 15, 7 p.70

    Research output: Contribution to journalArticle

  14. Neuronal deletion of GSK3beta increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2

    Liz, M. A., Mar, F. M., Santos, T. E., Pimentel, H. I., Marques, A. M., Morgado, M. M., Vieira, S., Sousa, V. F., Pemble, H., Wittmann, T., Sutherland, C., Woodgett, J. R. & Sousa, M. M. 12 Jun 2014 In : BMC Biology. 12, 47

    Research output: Contribution to journalArticle

  15. The phosphorylation of endogenous Nedd4-2 In Na+-absorbing human airway epithelial cells

    Ismail, N. A. S., Baines, D. L. & Wilson, S. M. 5 Jun 2014 In : European Journal of Pharmacology. 732, p. 32-42 11 p.

    Research output: Contribution to journalArticle

  16. 112 B-type natriuretic peptide is associated with future rise in Lv mass in optimally treated primary prevention population

    Nadir, A., Gandy, S. & Struthers, A. Jun 2014 In : Heart (British Cardiac Society). 100 , suppl 3, p. A64-A65 2 p.

    Research output: Contribution to journalMeeting abstract

  17. 60 insulin resistance is associated with all-cause mortality and accelerates the risk of progression to diabetes in non-diabetic heart failure patients

    Mohan, M., Deshmukh, H., Maria Choy, A. & Lang, C. Jun 2014 In : Heart. 100 , s3, p. A34 1 p.

    Research output: Contribution to journalMeeting abstract

  18. Discovering new biomarkers for predicting treatment response in heart failure using plasma proteomics

    Huy, T. C., Quinn, P. A., Sandhu, J. K., Voors, A. A., Parry, H., Lang, C. C., Jones, D. J. L. & Ng, L. L. Jun 2014 In : Heart (British Cardiac Society). 100 , Suppl 3, p. A30

    Research output: Contribution to journalMeeting abstract

  19. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W. , Heggie, A. , Barnett, A. , Cederberg, H. , Hansen, T. H. , Koopman, A. D. , Ridderstråle, M. , Rutters, F. , Vestergaard, H. , Gupta, R. , Herrgård, S. , Heymans, M. W. , Perry, M. H. , Rauh, S. , Siloaho, M. , Teare, H. J. A. , Thorand, B. , Bell, J. , Brunak, S. , Frost, G. & 14 others Jablonka, B., Mari, A., McDonald, T. J., Dekker, J. M., Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & DIRECT Consortium Jun 2014 In : Diabetologia. 57, 6, p. 1132-1142 11 p.

    Research output: Contribution to journalArticle

  20. Effectiveness of newspaper advertising for patient recruitment into a clinical trial

    Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S. Jun 2014 In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

    Research output: Contribution to journalArticle

  21. Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

    Zhou, K., Donnelly, L., Yang, J., Li, M., Deshmukh, H., Van Zuydam, N., Ahlqvist, E., Spencer, C. C., Groop, L., Morris, A. D., Colhoun, H. M., Sham, P. C., McCarthy, M. I., Palmer, C. N. A. & Pearson, E. R. Jun 2014 In : The Lancet Diabetes and Endocrinology. 2, 6, p. 481-487 7 p.

    Research output: Contribution to journalArticle

  22. Renal artery stenosis-when to screen, what to stent?

    Jennings, C. G., Houston, J. G., Severn, A., Bell, S., Mackenzie, I. S. & MacDonald, T. M. Jun 2014 In : Current Atherosclerosis Reports. 16, 6, 9 p.416

    Research output: Contribution to journalArticle

  23. Review article: 2014 UK consensus guidelines - hepatitis C management and direct-acting anti-viral therapy

    Miller, M. H., Agarwal, K., Austin, A., Brown, A., Barclay, S. T., Dundas, P., Dusheiko, G. M., Foster, G. R., Fox, R., Hayes, P. C., Leen, C., Millson, C., Ryder, S. D., Tait, J., Ustianowski, A. & Dillon, J. F. Jun 2014 In : Alimentary Pharmacology & Therapeutics. 39, 12, p. 1363-1375 13 p.

    Research output: Contribution to journalArticle

  24. Review article: 2014 UK consensus guidelines - hepatitis C management and direct-acting anti-viral therapy

    Miller, M. H., Agarwal, K., Austin, A., Brown, A., Barclay, S. T., Dundas, P., Dusheiko, G. M., Foster, G. R., Fox, R., Hayes, P. C., Leen, C., Millson, C., Ryder, S. D., Tait, J., Ustianowski, A. & Dillon, J. F. Jun 2014 In : Alimentary Pharmacology & Therapeutics. 39, 12, p. 1363-1375 13 p.

    Research output: Contribution to journalArticle

  25. A world without hepatitis C

    Ryder, S. & Dillon, J. 9 May 2014 In : Health Service Journal. 124, 6397, p. 21-23 3 p.

    Research output: Contribution to journalArticle

  26. Prediction of liver disease in patients whose liver function tests have been checked in primary care: model development and validation using population-based observational cohorts

    McLernon, D. J., Donnan, P. T., Sullivan, F. M., Roderick, P., Rosenberg, W. M., Ryder, S. D. & Dillon, J. F. May 2014 In : BMJ Open. 4, 6, 10 p.e004837

    Research output: Contribution to journalArticle

  27. Defining severity in non-cystic fibrosis bronchiectasis

    Poppelwell, L. & Chalmers, J. D. Apr 2014 In : Expert Review of Respiratory Medicine. 8, 2, p. 249-62 14 p.

    Research output: Contribution to journalArticle

  28. Modulation of the Renin-Angiotensin-aldosterone system in heart failure

    George, J., Struthers, A. D. & Lang, C. C. Apr 2014 In : Current Atherosclerosis Reports. 16, 4, p. 403 1 p.

    Research output: Contribution to journalArticle

  29. Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids

    Vijverberg, S. J. H., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Palmer, C. N. A. & Maitland-Van Der Zee, A. H. Apr 2014 In : Pharmacogenomics. 15, 6, p. 799-806 8 p.

    Research output: Contribution to journalArticle

  30. RD Lawrence Lecture 2013: Stratified approaches to the management of diabetes

    Pearson, E. Apr 2014 In : Diabetic Medicine. 31, 4, p. 393-398 6 p.

    Research output: Contribution to journalArticle

  31. Review of the British Thoracic Society Winter Meeting 2013, 4-6 December, London, UK

    Chalmers, J. D., Greening, N. J., José, R. J., Janes, S. M. & BTS Science and Research Committee Apr 2014 In : Thorax. 69, 4, p. 378-382 5 p.

    Research output: Contribution to journalArticle

  32. Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial

    Witham, M. D., Ireland, S., Houston, J. G., Gandy, S. J., Waugh, S., MacDonald, T. M., Mackenzie, I. S. & Struthers, A. D. Apr 2014 In : Hypertension. 63, 4, p. 706-712 7 p.

    Research output: Contribution to journalArticle

  33. Zinc transport and diabetes risk

    Pearson, E. Apr 2014 In : Nature Genetics. 46, 4, p. 323-4 2 p.

    Research output: Contribution to journalArticle

  34. Nasal cells

    Mehta, A. 26 Mar 2014

    Research output: Contribution to conferencePaper

  35. NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegans

    Fancsalszky, L., Monostori, E., Farkas, Z., Pourkarimi, E., Masoudi, N., Hargitai, B., Bosnar, M. H., Deželjin, M., Zsákai, A., Vellai, T., Mehta, A. & Takács-Vellai, K. 21 Mar 2014 In : PLoS ONE. 9, 3, 12 p.e92687

    Research output: Contribution to journalArticle

  36. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  37. Simplification of the IDSA/ATS criteria for severe CAP using meta-analysis and observational data

    Salih, W., Schembri, S. & Chalmers, J. D. 1 Mar 2014 In : European Respiratory Journal. 43, 3, p. 842-851 10 p.

    Research output: Contribution to journalArticle

  38. AMPK: regulating energy balance at the cellular and whole body levels

    Hardie, D. G. & Ashford, M. L. J. Mar 2014 In : Physiology. 29, 2, p. 99-107 9 p.

    Research output: Contribution to journalArticle

  39. Cholesteryl ester transfer protein polymorphisms, statin use, and their impact on cholesterol levels and cardiovascular events

    Morris, A. D. & 23 others Leusink, M., Onland-Moret, N. C., Asselbergs, F. W., Ding, B., Kotti, S., van Zuydam, N. R., Papp, A. C., Danchin, N., Donnelly, L., Chasman, D. I., Doevendans, P. A. F. M., Klungel, O. H., Ridker, P. M., van Gilst, W. H., Simon, T., Nyberg, F., Palmer, C. N. A., Sadee, W., van der Harst, P., de Bakker, P. I. W., de Boer, A., Verstuyft, C. & Maitland-van der Zee, A. H. Mar 2014 In : Clinical Pharmacology & Therapeutics. 95, 3, p. 314-320 7 p.

    Research output: Contribution to journalArticle

  40. Commentary: real-world triple therapy experience treating hepatitis C virus

    Heron, T., Miller, M. H. & Dillon, J. F. Mar 2014 In : Alimentary Pharmacology & Therapeutics. 39, 5, p. 542-542 1 p.

    Research output: Contribution to journalArticle

  41. The impact of age and chronic kidney disease on secondary prevention post-primary percutaneous coronary intervention

    Zachariah, D., Brown, R., Kanagala, P., Bashir, A., Mohan, M., Callan, P., Rajendra, R., Clark, A. L., Squire, I., Gunning, M., Lang, C. C. & Kalra, P. R. Mar 2014 In : QJM : an International Journal of Medicine. 107, 3, p. 185-192

    Research output: Contribution to journalArticle

  42. Healthcare associated pneumonia does not accurately identify potentially resistant pathogens: a systematic review and meta-analysis

    Chalmers, J. D., Rother, C., Salih, W. & Ewig, S. 1 Feb 2014 In : Clinical Infectious Diseases. 58, 3, p. 330-339 10 p.

    Research output: Contribution to journalArticle

  43. Reply: pharmacological obfuscation of clinical relevance

    Lipworth, B., Short, P., Anderson, W. & Williamson, P. 1 Feb 2014 In : American Journal of Respiratory and Critical Care Medicine. 189, 3, p. 360-361 2 p.

    Research output: Contribution to journalLetter

  44. A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections

    Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D. Feb 2014 In : Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.

    Research output: Contribution to journalArticle

  45. Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

    Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J. Feb 2014 In : Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

    Research output: Contribution to journalArticle

  46. Macrolides and mortality in severe community-acquired pneumonia*

    Chalmers, J. D. Feb 2014 In : Critical Care Medicine. 42, 2, p. 475-477 3 p.

    Research output: Contribution to journalEditorial

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