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Division of Cardiovascular & Diabetes Medicine

  1. Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

    Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P. 1 Apr 2016 In : Psychoneuroendocrinology. 66, p. 214-220 7 p.

    Research output: Contribution to journalArticle

  2. Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance

    Connelly, P. J., Smith, N., Chadwick, R., Exley, A. R., Shneerson, J. M. & Pearson, E. R. Mar 2016 In : Diabetic Medicine. 33, 3, p. 371-375 5 p.

    Research output: Contribution to journalArticle

  3. Educational class inequalities in the incidence of coronary heart disease in Europe

    Veronesi, G. , Ferrario, M. M. , Kuulasmaa, K. , Bobak, M. , Chambless, L. E. , Salomaa, V. , Soderberg, S. , Pajak, A. , Jørgensen, T. , Amouyel, P. , Arveiler, D. , Drygas, W. , Ferrieres, J. , Giampaoli, S. , Kee, F. , Iacoviello, L. , Malyutina, S. , Peters, A. , Tamosiunas, A. & 2 others Tunstall-Pedoe, H. & Cesana, G. 5 Feb 2016 In : Heart.

    Research output: Contribution to journalArticle

  4. Of mice and men-the curious tale of β blockers in asthma

    Lipworth, B. & Jabbal, S. 2 Feb 2016 In : The Lancet Respiratory Medicine. 4, 2, p. 89-91 3 p.

    Research output: Contribution to journalComment/debate

  5. Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

    Brown, M. J., Williams, B., Morant, S. V., Webb, D. J., Caulfield, M. J., Cruickshank, J. K., Ford, I., McInnes, G., Sever, P., Salsbury, J., Mackenzie, I. S., Padmanabhan, S., MacDonald, T. M. & for the British Hypertension Society's Prevention, Treatment of Hypertension with Algorithm-based Therapy (PATHWAY) Studies Group Feb 2016 In : The Lancet: Diabetes and Endocrinology. 4, 2, p. 136-147 12 p.

    Research output: Contribution to journalArticle

  6. Can antioxidant-rich blackcurrant juice drink consumption improve photoprotection against ultraviolet radiation?

    Ray, S., Belch, J. J., Craigie, A. M., Khan, F., Kennedy, G., Hill, A., Barton, K. L., Dawe, R. S. & Ibbotson, S. H. 24 Jan 2016 In : British Journal of Dermatology.

    Research output: Contribution to journalArticle

  7. Efficacy of the Ulnar-Basilic Arteriovenous Fistula for Hemodialysis: A Systematic Review

    Al Shakarchi, J., Khawaja, A., Cassidy, D., Houston, J. G. & Inston, N. 22 Jan 2016 In : Annals of Vascular Surgery. 4 p.

    Research output: Contribution to journalArticle

  8. Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

    Manoharan, A., Morrison, A. E. & Lipworth, B. 13 Jan 2016 In : Lung. 8 p.

    Research output: Contribution to journalArticle

  9. Psychoactive prescribing for older people-what difference does 15 years make?

    Hughes, L. D., Cochrane, L., McMurdo, M. E. T. & Guthrie, B. 1 Jan 2016 In : International Journal of Geriatric Psychiatry. 31, 1, p. 49-57 9 p.

    Research output: Contribution to journalArticle

  10. From mouse to man: Predicting biased effects of beta-blockers in asthma

    Lipworth, B. J., Anderson, W. J. & Short, P. M. Jan 2016 In : British Journal of Pharmacology. 173, 1, p. 248-249 2 p.

    Research output: Contribution to journalLetter

  11. Inhaled corticosteroid dose-response on blood eosinophils in asthma

    Lipworth, B., Jabbal, S., Manoharan, A., Anderson, W. & Short, P. Jan 2016 In : The Lancet Respiratory Medicine. 4, 1, p. e1

    Research output: Contribution to journalLetter

  12. Initiation of insulin adjustment for carbohydrate at onset of diabetes in children using a home‐based education programme with a bolus calculator

    Thom, H., Greene, S., Alexander, V., Ramsay, V., Bluff, S., Mackenzie, L., Sturrock, C. & Conway, N. T. 2016 In : Practical Diabetes. 33, 1, p. 19-22a 5 p.

    Research output: Contribution to journalArticle

  13. The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large ‘real world’ cohort

    Wang, H., Innes, H., Hutchinson, S. J., Goldberg, D. J., Allen, S., Barclay, S. T., Bramley, P., Fox, R., Fraser, A., Hayes, P. C., Kennedy, N., Mills, P. R. & Dillon, J. F. 21 Dec 2015 In : European Journal of Gastroenterology & Hepatology.

    Research output: Contribution to journalArticle

  14. The copper binding properties of metformin - QCM-D, XPS and nanobead agglomeration

    Quan, X., Uddin, R., Heiskanen, A., Parmvi, M., Nilson, K., Donolato, M., Hansen, M. F., Rena, G. & Boisen, A. 18 Dec 2015 In : Chemical Communications. 51, 97, p. 17313-17316 4 p.

    Research output: Contribution to journalArticle

  15. Protein phosphatase 1c associated with the cardiac sodium calcium exchanger1 regulates its activity by dephosphorylating serine 68 phosphorylated phospholemman

    Lubelwana Hafver, T., Hodne, K., Wanichawan, P., Aronsen, J. M., Dalhus, B., Lunde, P. K., Lunde, M., Martinsen, M., Enger, U. H., Fuller, W., Sjaastad, I., Louch, W. E., Sejersted, O. M. & Carlson, C. R. 14 Dec 2015 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  16. Decision support for diabetes: implementation and evaluation of the EBMeDS project within NHS Scotland

    Conway, N., Cunningham, S., Forbes, P., Shaik, F., Emslie-Smith, A., Wales, A. & Wake, D. 1 Dec 2015

    Research output: Contribution to conferencePoster

  17. Health state utilities associated with attributes of treatments for hepatitis C

    Matza, L. S., Sapra, S. J., Dillon, J. F., Kalsekar, A., Davies, E. W., Devine, M. K., Jordan, J. B., Landrian, A. S. & Feeny, D. H. 1 Dec 2015 In : European Journal of Health Economics. 16, 9, p. 1005-1018 14 p.

    Research output: Contribution to journalArticle

  18. Clinical practice guidelines and the older patient: wake up call for geriatricians

    Vilches-Moraga, A., Martinez-Velilla, N., Cherubini, A., McMurdo, M., Singh, I. & Pattison, T. Dec 2015 In : European Geriatric Medicine. 6, 6, p. 513-514 2 p.

    Research output: Contribution to journalEditorial

  19. Etiology of non-cystic fibrosis bronchiectasis in adults and its correlation to disease severity

    Lonni, S., Chalmers, J. D., Goeminne, P. C., McDonnell, M. J., Dimakou, K., De Soyza, A., Polverino, E., Van De Kerkhove, C., Rutherford, R., Davison, J., Rosales, E., Pesci, A., Restrepo, M. I., Torres, A. & Aliberti, S. Dec 2015 In : Annals of the American Thoracic Society. 12, 12, p. 1764-1770 7 p.

    Research output: Contribution to journalArticle

  20. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

    Morris, A. P. & 97 others Artigas, M. S., Wain, L. V., Miller, S., Kheirallah, A. K., Huffman, J. E., Ntalla, I., Shrine, N., Obeidat, M., Trochet, H., McArdle, W. L., Alves, A. C., Hui, J., Zhao, J. H., Joshi, P. K., Teumer, A., Albrecht, E., Imboden, M., Rawal, R., Lopez, L. M., Marten, J., Enroth, S., Surakka, I., Polasek, O., Lyytikäinen, L. P., Granell, R., Hysi, P. G., Flexeder, C., Mahajan, A., Beilby, J., Bossé, Y., Brandsma, C. A., Campbell, H., Gieger, C., Gläser, S., González, J. R., Grallert, H., Hammond, C. J., Harris, S. E., Hartikainen, A. L., Heliövaara, M., Henderson, J., Hocking, L., Horikoshi, M., Hutri-Kähönen, N., Ingelsson, E., Johansson, Å., Kemp, J. P., Kolcic, I., Kumar, A., Lind, L., Melén, E., Musk, A. W., Navarro, P., Nickle, D. C., Padmanabhan, S., Raitakari, O. T., Ried, J. S., Ripatti, S., Schulz, H., Scott, R. A., Sin, D. D., Starr, J. M., Viñuela, A., Völzke, H., Wild, S. H., Wright, A. F., Zemunik, T., Jarvis, D. L., Spector, T. D., Evans, D. M., Lehtimäki, T., Vitart, V., Kähönen, M., Gyllensten, U., Rudan, I., Deary, I. J., Karrasch, S., Probst-Hensch, N. M., Heinrich, J., Stubbe, B., Wilson, J. F., Wareham, N. J., James, A. L., Jarvelin, M. R., Hayward, C., Sayers, I., Strachan, D. P., Hall, I. P., Tobin, M. D., Deloukas, P., Hansell, A. L., Hubbard, R., Jackson, V. E., Marchini, J., Pavord, I., Thomson, N. C. & Zeggini, E. Dec 2015 In : Nature Communications. 6, 89658

    Research output: Contribution to journalArticle

  21. Implementation of the Lancet Standing Commission on liver disease in the UK

    Williams, R. , Ashton, K. , Aspinall, R. , Bellis, M. A. , Bosanquet, J. , Cramp, M. E. , Day, N. , Dhawan, A. , Dillon, J. , Dyson, J. , Ferguson, J. , Foster, G. , Gilmore, I. , Glynn, M. , Guthrie, J. A. , Hudson, M. , Kelly, D. , Langford, A. , Newsome, P. & 6 others O'Grady, J., Pryke, R., Ryder, S., Samyn, M., Sheron, N. & Verne, J. 21 Nov 2015 In : Lancet. 386, 10008, p. 2098-2111 14 p.

    Research output: Contribution to journalArticle

  22. Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

    Williams, B., MacDonald, T. M., Morant, S., Webb, D. J., Sever, P., McInnes, G., Ford, I., Cruickshank, J. K., Caulfield, M. J., Salsbury, J., Mackenzie, I., Padmanabhan, S., Brown, M. J. & or The British Hypertension Society's PATHWAY Studies Group 21 Nov 2015 In : Lancet. 386, 10008, p. 2059-2068 10 p.

    Research output: Contribution to journalArticle

  23. Thiel soft embalmed Porcine Kidney Perfusion Model for focused ultrasound therapy

    Wang, J., Xiao, X., Duncan, R., Karakitsios, I., Huang, Z., McLeod, H. & Melzer, A. 13 Nov 2015 2015 IEEE International Ultrasonics Symposium, IUS 2015. Institute of Electrical and Electronics Engineers, 7329408

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  24. Risk of postoperative acute kidney injury in patients undergoing orthopaedic surgery—development and validation of a risk score and effect of acute kidney injury on survival: observational cohort study

    Bell, S., Dekker, F. W., Vadiveloo, T., Marwick, C., Deshmukh, H., Donnan, P. T. & Van Diepen, M. 11 Nov 2015 In : BMJ. 351, 9 p., h5639

    Research output: Contribution to journalArticle

  25. tRNA methyltransferase homologue gene TRMT10A mutation in young adult-onset diabetes with intellectual disability, microcephaly and epilepsy

    Yew, T. W., McCreight, L., Colclough, K., Ellard, S. & Pearson, E. R. 3 Nov 2015 In : Diabetic Medicine.

    Research output: Contribution to journalArticle

  26. Strategies for the treatment of Hepatitis C in an era of interferon-free therapies: what public health outcomes do we value most?

    Innes, H., Goldberg, D., Dillon, J. & Hutchinson, S. J. 1 Nov 2015 In : Gut. 64, 11, p. 1800-1809 10 p.

    Research output: Contribution to journalArticle

  27. Association between kidney function, rehabilitation outcome, and survival in older patients discharged from inpatient rehabilitation

    Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D. Nov 2015 In : American Journal of Kidney Diseases. 66, 5, p. 768-774 7 p.

    Research output: Contribution to journalArticle

  28. Association between retinal vasculature and muscle mass in older people

    Sumukadas, D., McMurdo, M., Pieretti, I., Ballerini, L., Price, R., Wilson, P., Doney, A., Leese, G. & Trucco, E. Nov 2015 In : Archives of Gerontology and Geriatrics. 61, 3, p. 425-428 4 p.

    Research output: Contribution to journalArticle

  29. Early diagnosis improves outcomes in hepatitis C

    Miller, M. H. & Dillon, J. F. Nov 2015 In : Practitioner. 259, 1787, p. 25-27 3 p.

    Research output: Contribution to journalArticle

  30. The role of pulmonary arterial stiffness in COPD

    Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G. Nov 2015 In : Respiratory Medicine. 109, 11, p. 1381-1390 10 p.

    Research output: Contribution to journalArticle

  31. A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain

    Meng, W., Deshmukh, H. A., Donnelly, L. A., Wellcome Trust Case Control Consortium 2 (WTCCC2), Surrogate markers for Micro- and Macro-vascular hard endpoints for Innovative diabetes Tools (SUMMIT) study group, Torrance, N., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H. Oct 2015 In : EBioMedicine. 2, 10, p. 1386-1393 8 p.

    Research output: Contribution to journalArticle

  32. Comparative ergonomic workflow and user experience analysis of MRI versus fluoroscopy-guided vascular interventions: an iliac angioplasty exemplar case study

    Fernández-Gutiérrez, F., Martínez, S., Rube, M. A., Cox, B. F., Fatahi, M., Scott-Brown, K. C., Houston, J. G., McLeod, H., White, R. D., French, K., Gueorguieva, M., Immel, E. & Melzer, A. Oct 2015 In : International Journal of Computer Assisted Radiology and Surgery. 10, 10, p. 1639-1650 12 p.

    Research output: Contribution to journalArticle

  33. Management of noncardiac comorbidities in chronic heart failure

    Chong, V. H., Singh, J., Parry, H., Saunders, J., Chowdhury, F., Mancini, D. M. & Lang, C. C. Oct 2015 In : Cardiovascular Therapeutics. 33, 5, p. 300-315 16 p.

    Research output: Contribution to journalArticle

  34. Secreted mucins and airway bacterial colonization in non-CF bronchiectasis

    Sibila, O., Suarez-Cuartin, G., Rodrigo-Troyano, A., Fardon, T. C., Finch, S., Mateus, E. F., Garcia-Bellmunt, L., Castillo, D., Vidal, S., Sanchez-Reus, F., Restrepo, M. I. & Chalmers, J. D. Oct 2015 In : Respirology . 20, 7, p. 1082-1088 7 p.

    Research output: Contribution to journalArticle

  35. Spironolactone for people aged 70 or over with osteoarthritic knee pain: a proof of concept trial

    McMurdo, M. E. T., Sumukadas, D., Donnan, P. T., Cvoro, V., Rauchhaus, P., Argo, I., Waldie, H., Littleford, R., Struthers, A. D. & Witham, M. D. 28 Sep 2015 In : Arthritis Care & Research.

    Research output: Contribution to journalArticle

  36. Cohort comparison study of cardiac disease and atherosclerotic burden in type 2 diabetic adults using whole body cardiovascular magnetic resonance imaging

    Duce, S. L., Weir-McCall, J. R., Gandy, S. J., Matthew, S. Z., Cassidy, D. B., McCormick, L., Rauchhaus, P., Looker, H., Colhoun, H. M. & Houston, J. G. 18 Sep 2015 In : Cardiovascular Diabetology. 14, 11 p., 122

    Research output: Contribution to journalArticle

  37. Construction of a linked health and social care database resource: lessons on process, content and culture

    Witham, M. D., Frost, H., McMurdo, M., Donnan, P. T. & McGilchrist, M. 1 Sep 2015 In : Informatics for Health and Social Care. 40, 3, p. 229-239 11 p.

    Research output: Contribution to journalArticle

  38. Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlate with [Na]i

    Eykyn, T. R., Aksentijević, D., Aughton, K. L., Southworth, R., Fuller, W. & Shattock, M. J. 1 Sep 2015 In : Journal of Molecular and Cellular Cardiology. 86, p. 95-101 7 p.

    Research output: Contribution to journalArticle

  39. Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study

    Belch, J. & 20 others Shore, A. C., Colhoun, H. M., Natali, A., Palombo, C., Östling, G., Aizawa, K., Kennbäck, C., Casanova, F., Persson, M., Gates, P. E., Kahn, F., Looker, H. C., Adams, F., Pinnoli, S., Venturi, E., Morizzo, C., Goncalves, I., Ladenvall, C., Nilsson, J. & on behalf of the SUMMIT consortium Sep 2015 In : Journal of Internal Medicine. 278, 3, p. 291-302 12 p.

    Research output: Contribution to journalArticle

  40. mHealth applications for diabetes – user preference and implications for app development

    Conway, N., Campbell, I., Forbes, P., Cunningham, S. & Wake, D. 26 Aug 2015

    Research output: Contribution to conferencePoster

  41. Monotherapy versus dual therapy for the initial treatment of hypertension (PATHWAY-1): a randomised double-blind controlled trial

    MacDonald, T. M., Williams, B., Caulfield, M., Cruickshank, J. K., McInnes, G., Sever, P., Webb, D. J., Mackenzie, I. S., Salsbury, J., Morant, S., Ford, I. & Brown, M. J. 7 Aug 2015 In : BMJ Open. 5, 8, 7 p., e007645

    Research output: Contribution to journalArticle

  42. Bacillus anthracis meningitis during an outbreak of injectional anthrax, Scotland, UK

    Dewar, S., Weir-McCall, J. R., Batchelor, L., Cole, S. & Parcell, B. J. 1 Aug 2015 In : Clinical Microbiology and Infection. 21, 8, p. e49-e50 2 p.

    Research output: Contribution to journalArticle

  43. Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)?: Study protocol for a randomized controlled trial

    Witham, M. D., Band, M. M., Littleford, R. C., Avenell, A., Soiza, R. L., McMurdo, M. E. T., Sumukadas, D., Ogston, S. A., Lamb, E. J., Hampson, G., McNamee, P. & BiCARB study group 1 Aug 2015 In : Trials. 16, 326

    Research output: Contribution to journalArticle

  44. Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial

    Witham, M. D., Band, M. M., Littleford, R. C., Avenell, A., Soiza, R. L., McMurdo, M. E. T., Sumukadas, D., Ogston, S. A., Lamb, E. J., Hampson, G., McNamee, P. & for the BiCARB study group 1 Aug 2015 In : Trials. 16, 9 p., 326

    Research output: Contribution to journalArticle

  45. Conspecific recognition and aggression reduction to familiars in newly weaned, socially plastic mammals

    Robinson, K. J., Twiss, S. D., Hazon, N., Moss, S., Lonergan, M. & Pomeroy, P. P. Aug 2015 In : Behavioral Ecology and Sociobiology. 69, 8, p. 1383-1394 12 p.

    Research output: Contribution to journalArticle

  46. Impact of left ventricular hypertrophy on survival in chronic obstructive pulmonary disease

    Short, P. M., Anderson, W. J., Elder, D. H. J., Struthers, A. D. & Lipworth, B. J. Aug 2015 In : Lung. 193, 4, p. 487-495 9 p.

    Research output: Contribution to journalArticle

  47. No strong relationship between components of the lectin pathway of complement and susceptibility to pulmonary tuberculosis

    Chalmers, J. D., Matsushita, M., Kilpatrick, D. C. & Hill, A. T. Aug 2015 In : Inflammation. 38, 4, p. 1731-1737 7 p.

    Research output: Contribution to journalArticle

  48. Poster advertisements in practice waiting rooms to recruit patients to the Treatment In Morning vs. Evening (TIME) online study

    Rorie, D., Flynn, R., McConnachie, L., Mackenzie, I. S. & MacDonald, T. M. Aug 2015 In : British Journal of Clinical Pharmacology. 80, 2, p. 325-326

    Research output: Contribution to journalLetter

  49. Towards a more complete understanding of the association between a hepatitis C sustained viral response and cause-specific outcomes

    Innes, H. A., McDonald, S. A., Dillon, J. F., Allen, S., Hayes, P. C., Goldberg, D., Mills, P. R., Barclay, S. T., Wilks, D., Valerio, H., Fox, R., Bhattacharyya, D., Kennedy, N., Morris, J., Fraser, A., Stanley, A. J., Bramley, P. & Hutchinson, S. J. Aug 2015 In : Hepatology. 62, 2, p. 355-364 10 p.

    Research output: Contribution to journalArticle

  50. Underutilisation of IV nitrates in the treatment of acute heart failure

    Mohan, M., Hawkey, S., Baig, F., Choy, A. M. & Lang, C. C. Aug 2015 In : Cardiovascular Therapeutics. 33, 4, p. 247-252 6 p.

    Research output: Contribution to journalArticle

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