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  1. Proteomic and genomic studies of non-alcoholic fatty liver disease - clues in the pathogenesis

    Lim, J. W., Dillon, J. & Miller, M. 14 Jul 2014 In : World Journal of Gastroenterology . 20, 26, p. 8325-8340 16 p.

    Research output: Contribution to journalArticle

  2. CFTR functional measurements in human models for diagnosis, prognosis and personalized therapy: report on the pre-conference meeting to the 11th ECFS Basic Science Conference, Malta, 26-29 March 2014

    Beekman, J. M., Sermet-Gaudelus, I., de Boeck, K., Gonska, T., Derichs, N., Mall, M. A., Mehta, A., Martin, U., Drumm, M. & Amaral, M. D. Jul 2014 In : Journal of Cystic Fibrosis. 13, 4, p. 363-372 10 p.

    Research output: Contribution to journalArticle

  3. Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?

    Harrison, M. T., Short, P., Williamson, P. A., Singanayagam, A., Chalmers, J. D. & Schembri, S. Jul 2014 In : Thorax. 69, 7, p. 609-615 7 p.

    Research output: Contribution to journalArticle

  4. Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

    Norsworthy, P. J., Vandrovcova, J., Thomas, E. R. A., Campbell, A., Kerr, S. M., Biggs, J., Game, L., Soutar, A. K., Smith, B. H., Dominiczak, A. F., Porteous, D. J., Morris, A. D., Generation Scotland & Aitman, T. J. 23 Jun 2014 In : BMC Medical Genetics. 15, 7 p.70

    Research output: Contribution to journalArticle

  5. Neuronal deletion of GSK3beta increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2

    Liz, M. A., Mar, F. M., Santos, T. E., Pimentel, H. I., Marques, A. M., Morgado, M. M., Vieira, S., Sousa, V. F., Pemble, H., Wittmann, T., Sutherland, C., Woodgett, J. R. & Sousa, M. M. 12 Jun 2014 In : BMC Biology. 12, 47

    Research output: Contribution to journalArticle

  6. The phosphorylation of endogenous Nedd4-2 In Na+-absorbing human airway epithelial cells

    Ismail, N. A. S., Baines, D. L. & Wilson, S. M. 5 Jun 2014 In : European Journal of Pharmacology. 732, p. 32-42 11 p.

    Research output: Contribution to journalArticle

  7. 112 B-type Natriuretic Peptide is Associated with Future Rise in Lv Mass in Optimally Treated Primary Prevention Population

    Nadir, A., Gandy, S. & Struthers, A. Jun 2014 In : Heart (British Cardiac Society). 100 , Suppl 3, p. A64-A65

    Research output: Contribution to journalMeeting abstract

  8. 60 insulin resistance is associated with all-cause mortality and accelerates the risk of progression to diabetes in non-diabetic heart failure patients

    Mohan, M., Deshmukh, H., Maria Choy, A. & Lang, C. Jun 2014 In : Heart. 100 , s3, p. A34 1 p.

    Research output: Contribution to journalMeeting abstract

  9. Discovering new biomarkers for predicting treatment response in heart failure using plasma proteomics

    Huy, T. C., Quinn, P. A., Sandhu, J. K., Voors, A. A., Parry, H., Lang, C. C., Jones, D. J. L. & Ng, L. L. Jun 2014 In : Heart (British Cardiac Society). 100 , Suppl 3, p. A30

    Research output: Contribution to journalMeeting abstract

  10. Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W. , Heggie, A. , Barnett, A. , Cederberg, H. , Hansen, T. H. , Koopman, A. D. , Ridderstråle, M. , Rutters, F. , Vestergaard, H. , Gupta, R. , Herrgård, S. , Heymans, M. W. , Perry, M. H. , Rauh, S. , Siloaho, M. , Teare, H. J. A. , Thorand, B. , Bell, J. , Brunak, S. , Frost, G. & 14 others Jablonka, B., Mari, A., McDonald, T. J., Dekker, J. M., Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & DIRECT Consortium Jun 2014 In : Diabetologia. 57, 6, p. 1132-1142 11 p.

    Research output: Contribution to journalArticle

  11. Effectiveness of newspaper advertising for patient recruitment into a clinical trial

    Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S. Jun 2014 In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

    Research output: Contribution to journalArticle

  12. Impact of Long-Acting Bronchodilators and Exposure to Inhaled Corticosteroids on Mortality in COPD: A Real-Life Retrospective Cohort Study

    Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J. Jun 2014 In : Lung.

    Research output: Contribution to journalArticle

  13. Renal artery stenosis-when to screen, what to stent?

    Jennings, C. G., Houston, J. G., Severn, A., Bell, S., Mackenzie, I. S. & MacDonald, T. M. Jun 2014 In : Current Atherosclerosis Reports. 16, 6, 9 p.416

    Research output: Contribution to journalArticle

  14. Review article: 2014 UK consensus guidelines - hepatitis C management and direct-acting anti-viral therapy

    Miller, M. H., Agarwal, K., Austin, A., Brown, A., Barclay, S. T., Dundas, P., Dusheiko, G. M., Foster, G. R., Fox, R., Hayes, P. C., Leen, C., Millson, C., Ryder, S. D., Tait, J., Ustianowski, A. & Dillon, J. F. Jun 2014 In : Alimentary Pharmacology & Therapeutics. 39, 12, p. 1363-1375 13 p.

    Research output: Contribution to journalArticle

  15. The European Cystic Fibrosis Society Patient Registry: valuable lessons learned on how to sustain a disease registry

    Viviani, L., Zolin, A., Mehta, A. & Olesen, H. V. Jun 2014 In : Orphanet Journal of Rare Diseases. 9, 14 p.81

    Research output: Contribution to journalArticle

  16. A world without hepatitis C

    Ryder, S. & Dillon, J. 9 May 2014 In : Health Service Journal. 124, 6397, p. 21-23 3 p.

    Research output: Contribution to journalArticle

  17. Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes

    Hamilton, D. L., Findlay, J. A., Montagut , G., Meakin, P. J., Bestow, D., Jalicy, S. M. & Ashford, M. L. J. May 2014 In : Diabetologia.

    Research output: Contribution to journalArticle

  18. Prediction of liver disease in patients whose liver function tests have been checked in primary care: model development and validation using population-based observational cohorts

    McLernon, D. J., Donnan, P. T., Sullivan, F. M., Roderick, P., Rosenberg, W. M., Ryder, S. D. & Dillon, J. F. May 2014 In : BMJ Open. 4, 6, 10 p.e004837

    Research output: Contribution to journalArticle

  19. Serum Ficolin-2 in hospitalised patients with community-acquired pneumonia

    Chalmers, J. D., Fleming, G. B., Rutherford, J., Matsushita, M., Kilpatrick, D. C. & Hill, A. T. 16 Apr 2014 In : Mediators of Inflammation .

    Research output: Contribution to journalArticle

  20. Modulation of the Renin-Angiotensin-aldosterone system in heart failure

    George, J., Struthers, A. D. & Lang, C. C. Apr 2014 In : Current Atherosclerosis Reports. 16, 4, p. 403 1 p.

    Research output: Contribution to journalArticle

  21. Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids

    Vijverberg, S. J. H., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Palmer, C. N. A. & Maitland-Van Der Zee, A. H. Apr 2014 In : Pharmacogenomics. 15, 6, p. 799-806 8 p.

    Research output: Contribution to journalArticle

  22. RD Lawrence Lecture 2013: Stratified approaches to the management of diabetes

    Pearson, E. Apr 2014 In : Diabetic Medicine. 31, 4, p. 393-398 6 p.

    Research output: Contribution to journalArticle

  23. Review of the British Thoracic Society Winter Meeting 2013, 4-6 December, London, UK

    Chalmers, J. D., Greening, N. J., José, R. J., Janes, S. M. & BTS Science and Research Committee Apr 2014 In : Thorax. 69, 4, p. 378-382 5 p.

    Research output: Contribution to journalArticle

  24. Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial

    Witham, M. D., Ireland, S., Houston, J. G., Gandy, S. J., Waugh, S., MacDonald, T. M., Mackenzie, I. S. & Struthers, A. D. Apr 2014 In : Hypertension. 63, 4, p. 706-712 7 p.

    Research output: Contribution to journalArticle

  25. Zinc transport and diabetes risk

    Pearson, E. Apr 2014 In : Nature Genetics. 46, 4, p. 323-4 2 p.

    Research output: Contribution to journalArticle

  26. Nasal cells

    Mehta, A. 26 Mar 2014

    Research output: Contribution to conferencePaper

  27. NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegans

    Fancsalszky, L., Monostori, E., Farkas, Z., Pourkarimi, E., Masoudi, N., Hargitai, B., Bosnar, M. H., Deželjin, M., Zsákai, A., Vellai, T., Mehta, A. & Takács-Vellai, K. 21 Mar 2014 In : PLoS ONE. 9, 3, 12 p.e92687

    Research output: Contribution to journalArticle

  28. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  29. Simplification of the IDSA/ATS criteria for severe CAP using meta-analysis and observational data

    Salih, W., Schembri, S. & Chalmers, J. D. 1 Mar 2014 In : European Respiratory Journal. 43, 3, p. 842-851 10 p.

    Research output: Contribution to journalArticle

  30. AMPK: regulating energy balance at the cellular and whole body levels

    Hardie, D. G. & Ashford, M. L. J. Mar 2014 In : Physiology. 29, 2, p. 99-107 9 p.

    Research output: Contribution to journalArticle

  31. Cholesteryl ester transfer protein polymorphisms, statin use, and their impact on cholesterol levels and cardiovascular events

    Morris, A. D. & 23 others Leusink, M., Onland-Moret, N. C., Asselbergs, F. W., Ding, B., Kotti, S., van Zuydam, N. R., Papp, A. C., Danchin, N., Donnelly, L., Chasman, D. I., Doevendans, P. A. F. M., Klungel, O. H., Ridker, P. M., van Gilst, W. H., Simon, T., Nyberg, F., Palmer, C. N. A., Sadee, W., van der Harst, P., de Bakker, P. I. W., de Boer, A., Verstuyft, C. & Maitland-van der Zee, A. H. Mar 2014 In : Clinical Pharmacology & Therapeutics. 95, 3, p. 314-320 7 p.

    Research output: Contribution to journalArticle

  32. Commentary: real-world triple therapy experience treating hepatitis C virus

    Heron, T., Miller, M. H. & Dillon, J. F. Mar 2014 In : Alimentary Pharmacology & Therapeutics. 39, 5, p. 542-542 1 p.

    Research output: Contribution to journalArticle

  33. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Morris, A. D. & 332 others Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B., Bao, Y., Barnett, A. H., Barroso, I., Basit, A., Been, L. F., Beilby, J., Bell, G. I., Benediktsson, R., Bergman, R. N., Boehm, B. O., Boerwinkle, E., Bonnycastle, L. L., Burtt, N., Cai, Q., Campbell, H., Carey, J., Cauchi, S., Caulfield, M., Chan, J. C. N., Chang, L-C., Chang, T-J., Chang, Y-C., Charpentier, G., Chen, C-H., Chen, H., Chen, Y-T., Chia, K-S., Chidambaram, M., Chines, P. S., Cho, N. H., Cho, Y. M., Chuang, L-M., Collins, F. S., Cornelis, M. C., Couper, D. J., Crenshaw, A. T., van Dam, R. M., Danesh, J., Das, D., de Faire, U., Dedoussis, G., Deloukas, P., Dimas, A. S., Dina, C., Doney, A. S. F., Donnelly, P. J., Dorkhan, M., van Duijn, C., Dupuis, J., Edkins, S., Elliott, P., Emilsson, V., Erbel, R., Eriksson, J. G., Escobedo, J., Esko, T., Eury, E., Florez, J. C., Fontanillas, P., Forouhi, N. G., Forsen, T., Fox, C., Fraser, R. M., Frayling, T. M., Froguel, P., Frossard, P., Gao, Y., Gertow, K., Gieger, C., Gigante, B., Grallert, H., Grant, G. B., Grrop, L. C., Groves, C. J., Grundberg, E., Guiducci, C., Hamsten, A., Han, B-G., Hara, K., Hassanali, N., Hattersley, A. T., Hayward, C., Hedman, A. K., Herder, C., Hofman, A., Holmen, O. L., Hovingh, K., Hreidarsson, A. B., Hu, C., Hu, F. B., Hui, J., Humphries, S. E., Hunt, S. E., Hunter, D. J., Hveem, K., Hydrie, Z. I., Ikegami, H., Illig, T., Ingelsson, E., Islam, M., Isomaa, B., Jackson, A. U., Jafar, T., James, A., Jia, W., Jöckel, K-H., Jonsson, A., Jowett, J. B. M., Kadowaki, T., Kang, H. M., Kanoni, S., Kao, W. H. L., Kathiresan, S., Kato, N., Katulanda, P., Keinanen-Kiukaanniemi, K. M., Kelly, A. M., Khan, H., Khaw, K-T., Khor, C-C., Kim, H-L., Kim, S., Kim, Y. J., Kinnunen, L., Klopp, N., Kong, A., Korpi-Hyövälti, E., Kowlessur, S., Kraft, P., Kravic, J., Kristensen, M. M., Krithika, S., Kumar, A., Kumate, J., Kuusisto, J., Kwak, S. H., Laakso, M., Lagou, V., Lakka, T. A., Langenberg, C., Langford, C., Lawrence, R., Leander, K., Lee, J-M., Lee, N. R., Li, M., Li, X., Li, Y., Liang, J., Liju, S., Lim, W-Y., Lind, L., Lindgren, C. M., Lindholm, E., Liu, C-T., Liu, J. J., Lobbens, S., Long, J., Loos, R. J. F., Lu, W., Luan, J., Lyssenko, V., Ma, R. C. W., Maeda, S., Mägi, R., Männisto, S., Matthews, D. R., Meigs, J. B., Melander, O., Metspalu, A., Meyer, J., Mirza, G., Mihailov, E., Moebus, S., Mohan, V., Mohlke, K. L., Mühleisen, T. W., Müller-Nurasyid, M., Musk, B., Nakamura, J., Nakashima, E., Navarro, P., Ng, P-K., Nica, A. C., Nilsson, P. M., Njølstad, I., Nöthen, M. M., Ohnaka, K., Ong, T. H., Owen, K. R., Palmer, C. N. A., Pankow, J. S., Park, K. S., Parkin, M., Pechlivanis, S., Pedersen, N. L., Peltonen, L., Perry, J. R. B., Peters, A., Pinidiyapathirage, J. M., Platou, C. G., Potter, S., Price, J. F., Qi, L., Radha, V., Rallidis, L., Rasheed, A., Rathman, W., Rauramaa, R., Raychaudhuri, S., Rayner, N. W., Rees, S. D., Rehnberg, E., Ripatti, S., Robertson, N., Roden, M., Rossin, E. J., Rudan, I., Rybin, D., Saaristo, T. E., Salomaa, V., Saltevo, J., Samuel, M., Sanghera, D. K., Saramies, J., Scott, J., Scott, L. J., Scott, R. A., Segrè, A. V., Sehmi, J., Sennblad, B., Shah, N., Shah, S., Shera, A. S., Shu, X. O., Shuldiner, A. R., Sigurđsson, G., Sijbrands, E., Silveira, A., Sim, X., Sivapalaratnam, S., Small, K. S., So, W. Y., Stančáková, A., Stefansson, K., Steinbach, G., Steinthorsdottir, V., Stirrups, K., Strawbridge, R. J., Stringham, H. M., Sun, Q., Suo, C., Syvänen, A-C., Takayanagi, R., Takeuchi, F., Tay, W. T., Teslovich, T. M., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tikkanen, E., Trakalo, J., Tremoli, E., Trip, M. D., Tsai, F. J., Tuomi, T., Tuomilehto, J., Uitterlinden, A. G., Valladares-Salgado, A., Vedantam, S., Veglia, F., Voight, B. F., Wang, C., Wareham, N. J., Wennauer, R., Wickremasinghe, A. R., Wilsgaard, T., Wilson, J. F., Wiltshire, S., Winckler, W., Wong, T. Y., Wood, A. R., Wu, J-Y., Wu, Y., Yamamoto, K., Yamauchi, T., Yang, M., Yengo, L., Yokota, M., Young, R., Zabaneh, D., Zhang, F., Zhang, R., Zheng, W., Zimmet, P. Z., Altshuler, D., Bowden, D. W., Cho, Y. S., Cox, N. J., Cruz, M., Hanis, C. L., Kooner, J., Lee, J-Y., Seielstad, M., Teo, Y. Y., Boehnke, M., Parra, E. J., Chambers, J. C., Tai, E. S., McCarthy, M. I., Morris, A. P. & DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium Mar 2014 In : Nature Genetics. 46, 3, p. 234-244 11 p.

    Research output: Contribution to journalArticle

  34. Healthcare associated pneumonia does not accurately identify potentially resistant pathogens: a systematic review and meta-analysis

    Chalmers, J. D., Rother, C., Salih, W. & Ewig, S. 1 Feb 2014 In : Clinical Infectious Diseases. 58, 3, p. 330-339 10 p.

    Research output: Contribution to journalArticle

  35. Reply: pharmacological obfuscation of clinical relevance

    Lipworth, B., Short, P., Anderson, W. & Williamson, P. 1 Feb 2014 In : American Journal of Respiratory and Critical Care Medicine. 189, 3, p. 360-361 2 p.

    Research output: Contribution to journalLetter

  36. A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections

    Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D. Feb 2014 In : Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.

    Research output: Contribution to journalArticle

  37. Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

    Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J. Feb 2014 In : Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

    Research output: Contribution to journalArticle

  38. Macrolides and mortality in severe community-acquired pneumonia*

    Chalmers, J. D. Feb 2014 In : Critical Care Medicine. 42, 2, p. 475-477 3 p.

    Research output: Contribution to journalEditorial

  39. The Kuwait-Scotland eHealth Innovation Network (KSeHIN): a sustainable approach to quality improvement in healthcare

    Conway, N. T. , Connell, J. , Morris, A. & 21 others Wotayan, R. A., Alkuzam, A., Al-Refaei, F. F., Badawi, D., Barake, R., Bell, A., Boyle, G., Chisholm, S., Emslie-Smith, A., Goddard, C. A., Greene, S. A., Halawa, N., Judson, A., Kelly, C., Ker, J., Scott, M., Shaltout, A., Sukkar, F., Wake, D., Sibbald, D. & Behbehani, K. Feb 2014 In : Quality in Primary Care. 22, 1, p. 43-51 9 p.

    Research output: Contribution to journalArticle

  40. Critical care transition and prevention of ICU readmissions: a bridge over troubled waters*

    Chalmers, J. D. & Black, E. Jan 2014 In : Critical Care Medicine. 42, 1, p. 216-217 2 p.

    Research output: Contribution to journalEditorial

  41. Emerging role of long acting muscarinic antagonists for asthma

    Lipworth, B. J. Jan 2014 In : British Journal of Clinical Pharmacology. 77, 1, p. 55-62 8 p.

    Research output: Contribution to journalScientific review

  42. Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database

    Mackenzie, I. S., Morant, S. V., Bloomfield, G. A., MacDonald, T. M. & O'Riordan, J. Jan 2014 In : Journal of Neurology, Neurosurgery & Psychiatry. 85, 1, p. 76-84 9 p.

    Research output: Contribution to journalArticle

  43. Kv1.3 inhibitors have differential effects on glucose uptake and AMPK activity in skeletal muscle cell lines and mouse ex vivo skeletal muscle

    Hamilton, D. L., Beall, C., Jeromson, S., Chevtzoff, C., Cuthbertson, D. J. & Ashford, M. L. J. Jan 2014 In : Journal of Physiological Sciences. 64, 1, p. 13-20 8 p.

    Research output: Contribution to journalArticle

  44. Myocardial ischaemia is associated with an elevated brain natriuretic pepide level even in the presence of left ventricular systolic dysfunction

    Nadir, M. A., Dow, E., Davidson, J., Kennedy, N., Lang, C. C. & Struthers, A. D. Jan 2014 In : European Journal of Heart Failure. 16, 1, p. 56-67 12 p.

    Research output: Contribution to journalArticle

  45. Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

    Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J. Jan 2014 In : Clinical Science. 126, 1, p. 75-83 9 p.

    Research output: Contribution to journalArticle

  46. The authors reply

    Wei, L., Macdonald, T. M. & Murphy, M. J. Jan 2014 In : Kidney International. 85, 1, p. 211 1 p.

    Research output: Contribution to journalLetter

  47. The role of neutrophils in cystic fibrosis

    Gifford, A. M. & Chalmers, J. D. Jan 2014 In : Current Opinion in Hematology. 21, 1, p. 16-22 7 p.

    Research output: Contribution to journalArticle

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