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Division of Population Health Sciences

  1. Construction of a linked health and social care database resource: lessons on process, content and culture

    Witham, M. D., Frost, H., McMurdo, M., Donnan, P. T. & McGilchrist, M. 1 Sep 2015 In : Informatics for Health and Social Care. 40, 3, p. 229-239 11 p.

    Research output: Contribution to journalArticle

  2. Elevated plasma levels of MMP-12 are associated with atherosclerotic burden and symptomatic cardiovascular disease in subjects with type 2 diabetes

    Khan, F. , Belch, J. & 24 others Goncalves, I., Bengtsson, E., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Edsfeldt, A., Dunér, P., Fredrikson, G. N., Björkbacka, H., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Strain, D., Looker, H. C., Adams, F., Pinnoli, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V. & Nilsson, J. 27 Jul 2015 In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 7, p. 1723-1731 9 p.

    Research output: Contribution to journalArticle

  3. Directional dominance on stature and cognition in diverse human populations

    Connell, J. , Smith, B. H. , Morris, A. D. & 357 others Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S., Guo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A-E., Kacprowski, T., Bjonnes, A., van der Spek, A., Wu, Y., Giri, A. K., Yanek, L. R., Wang, L., Hofer, E., Rietveld, C. A., McLeod, O., Cornelis, M. C., Pattaro, C., Verweij, N., Baumbach, C., Abdellaoui, A., Warren, H. R., Vuckovic, D., Mei, H., Bouchard, C., Perry, J. R. B., Cappellani, S., Mirza, S. S., Benton, M. C., Broeckel, U., Medland, S. E., Lind, P. A., Malerba, G., Drong, A., Yengo, L., Bielak, L. F., Zhi, D., van der Most, P. J., Shriner, D., Mägi, R., Hemani, G., Karaderi, T., Wang, Z., Liu, T., Demuth, I., Zhao, J. H., Meng, W., Lataniotis, L., van der Laan, S. W., Bradfield, J. P., Wood, A. R., Bonnefond, A., Ahluwalia, T. S., Hall, L. M., Salvi, E., Yazar, S., Carstensen, L., de Haan, H. G., Abney, M., Afzal, U., Allison, M. A., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Barr, R. G., Baumeister, S. E., Benjamin, D. J., Bergmann, S., Boerwinkle, E., Bottinger, E. P., Campbell, A., Chakravarti, A., Chan, Y., Chanock, S. J., Chen, C., Chen, Y-D. I., Collins, F. S., Correa, A., Cupples, L. A., Smith, G. D., Davies, G., Dörr, M., Ehret, G., Ellis, S. B., Feenstra, B., Feitosa, M. F., Ford, I., Fox, C. S., Frayling, T. M., Friedrich, N., Geller, F., Scotland, G., Gillham-Nasenya, I., Gottesman, O., Graff, M., Grodstein, F., Gu, C., Haley, C., Hammond, C. J., Harris, S. E., Harris, T. B., Hastie, N. D., Heard-Costa, N. L., Heikkilä, K., Hocking, L. J., Homuth, G., Hottenga, J-J., Huang, J., Huffman, J. E., Hysi, P. G., Ikram, M. A., Ingelsson, E., Joensuu, A., Johansson, Å., Jousilahti, P., Jukema, J. W., Kähönen, M., Kamatani, Y., Kanoni, S., Kerr, S. M., Khan, N. M., Koellinger, P., Koistinen, H. A., Kooner, M. K., Kubo, M., Kuusisto, J., Lahti, J., Launer, L. J., Lea, R. A., Lehne, B., Lehtimäki, T., Liewald, D. C. M., Lind, L., Loh, M., Lokki, M-L., London, S. J., Loomis, S. J., Loukola, A., Lu, Y., Lumley, T., Lundqvist, A., Männistö, S., Marques-Vidal, P., Masciullo, C., Matchan, A., Mathias, R. A., Matsuda, K., Meigs, J. B., Meisinger, C., Meitinger, T., Menni, C., Mentch, F. D., Mihailov, E., Milani, L., Montasser, M. E., Montgomery, G. W., Morrison, A., Myers, R. H., Nadukuru, R., Navarro, P., Nelis, M., Nieminen, M. S., Nolte, I. M., O'Connor, G. T., Ogunniyi, A., Padmanabhan, S., Palmas, W. R., Pankow, J. S., Patarcic, I., Pavani, F., Peyser, P. A., Pietilainen, K., Poulter, N., Prokopenko, I., Ralhan, S., Redmond, P., Rich, S. S., Rissanen, H., Robino, A., Rose, L. M., Rose, R., Sala, C., Salako, B., Salomaa, V., Sarin, A-P., Saxena, R., Schmidt, H., Scott, L. J., Scott, W. R., Sennblad, B., Seshadri, S., Sever, P., Shrestha, S., Smith, J. A., Soranzo, N., Sotoodehnia, N., Southam, L., Stanton, A. V., Stathopoulou, M. G., Strauch, K., Strawbridge, R. J., Suderman, M. J., Tandon, N., Tang, S-T., Taylor, K. D., Tayo, B. O., Töglhofer, A. M., Tomaszewski, M., Tšernikova, N., Tuomilehto, J., Uitterlinden, A. G., Vaidya, D., van Hylckama Vlieg, A., van Setten, J., Vasankari, T., Vedantam, S., Vlachopoulou, E., Vozzi, D., Vuoksimaa, E., Waldenberger, M., Ware, E. B., Wentworth-Shields, W., Whitfield, J. B., Wild, S., Willemsen, G., Yajnik, C. S., Yao, J., Zaza, G., Zhu, X., BioBank Japan Project, Salem, R. M., Melbye, M., Bisgaard, H., Samani, N. J., Cusi, D., Mackey, D. A., Cooper, R. S., Froguel, P., Pasterkamp, G., Grant, S. F. A., Hakonarson, H., Ferrucci, L., Scott, R. A., Palmer, C. N. A., Dedoussis, G., Deloukas, P., Bertram, L., Lindenberger, U., Berndt, S. I., Lindgren, C. M., Timpson, N. J., Tönjes, A., Munroe, P. B., Sørensen, T. I. A., Rotimi, C. N., Arnett, D. K., Oldehinkel, A. J., Kardia, S. L. R., Balkau, B., Gambaro, G., Morris, A. P., Eriksson, J. G., Wright, M. J., Martin, N. G., Hunt, S. C., Starr, J. M., Deary, I. J., Griffiths, L. R., Tiemeier, H., Pirastu, N., Kaprio, J., Wareham, N. J., Pérusse, L., Wilson, J. G., Girotto, G., Caulfield, M. J., Raitakari, O., Boomsma, D. I., Gieger, C., van der Harst, P., Hicks, A. A., Kraft, P., Sinisalo, J., Knekt, P., Johannesson, M., Magnusson, P. K. E., Hamsten, A., Schmidt, R., Borecki, I. B., Vartiainen, E., Becker, D. M., Bharadwaj, D., Mohlke, K. L., Boehnke, M., van Duijn, C. M., Sanghera, D. K., Teumer, A., Zeggini, E., Metspalu, A., Gasparini, P., Ulivi, S., Ober, C., Toniolo, D., Rudan, I., Porteous, D. J., Ciullo, M., Spector, T. D., Hayward, C., Dupuis, J., Loos, R. J. F., Wright, A. F., Chandak, G. R., Vollenweider, P., Shuldiner, A. R., Ridker, P. M., Rotter, J. I., Sattar, N., Gyllensten, U., North, K. E., Pirastu, M., Psaty, B. M., Weir, D. R., Laakso, M., Gudnason, V., Takahashi, A., Chambers, J. C., Kooner, J. S., Strachan, D. P., Campbell, H., Hirschhorn, J. N., Perola, M., Polašek, O. & Wilson, J. F. 23 Jul 2015 In : Nature. 523, 7561, p. 459-462 4 p.

    Research output: Contribution to journalArticle

  4. A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

    Morris, A. D. & 46 others Mosley, J. D., Shaffer, C. M., Van Driest, S. L., Weeke, P. E., Wells, Q. S., Karnes, J. H., Velez Edwards, D. R., Wei, W-Q., Teixeira, P. L., Bastarache, L., Crawford, D. C., Li, R., Manolio, T. A., Bottinger, E. P., McCarty, C. A., Linneman, J. G., Brilliant, M. H., Pacheco, J. A., Thompson, W., Chisholm, R. L., Jarvik, G. P., Crosslin, D. R., Carrell, D. S., Baldwin, E., Ralston, J., Larson, E. B., Grafton, J., Scrol, A., Jouni, H., Kullo, I. J., Tromp, G., Borthwick, K. M., Kuivaniemi, H., Carey, D. J., Ritchie, M. D., Bradford, Y., Verma, S. S., Chute, C. G., Veluchamy, A., Siddiqui, M. K., Palmer, C. N. A., Doney, A., MahmoudPour, S. H., Maitland-van der Zee, A. H., Denny, J. C. & Roden, D. M. 14 Jul 2015 In : Pharmacogenomics Journal.

    Research output: Contribution to journalArticle

  5. Calculation of limits for significant bidirectional changes in two or more serial results of a biomarker based on a computer simulation model

    Lund, F., Petersen, P. H., Fraser, C. G. & Sölétormos, G. Jul 2015 In : Annals of Clinical Biochemistry. 52, 4, p. 434-440 7 p.

    Research output: Contribution to journalArticle

  6. Colorectal adenomas and diabetes: implications for disease prevention

    Steele, R. J. C., Anderson, A. S., Macleod, M., Craigie, A. M., Caswell, S., Belch, J., Treweek, S. & on behalf of the BeWEL team Jul 2015 In : Colorectal Disease. 17, 7, p. 589-594 6 p.

    Research output: Contribution to journalArticle

  7. Copy number variation in the human Y chromosome in the UK population

    Wei, W., Fitzgerald, T., Ayub, Q., Massaia, A., Smith, B. B., Dominiczak, A. A., Morris, A. A., Porteous, D. D., Hurles, M. E., Tyler-Smith, C. & Xue, Y. Jul 2015 In : Human Genetics. 134, 7, p. 789-800 12 p.

    Research output: Contribution to journalArticle

  8. Erratum to: Copy number variation in the human Y chromosome in the UK population

    Wei, W., Fitzgerald, T. W., Ayub, Q., Massaia, A., Smith, B. H., Dominiczak, A. F., Morris, A. D., Porteous, D. J., Hurles, M. E., Tyler-Smith, C. & Xue, Y. Jul 2015 In : Human Genetics. 134, 7, p. 801 1 p.

    Research output: Contribution to journalArticle

  9. Interventions to prevent non-critical care hospital acquired pneumonia – a systematic review

    McAuley, S. M., Price, R. J. G., Phillips, G., Marwick, C. A., McMurdo, M. E. T. & Witham, M. D. Jul 2015 In : European Geriatric Medicine. 6, 4, p. 336-340 5 p.

    Research output: Contribution to journalArticle

  10. NSAID exacerbated respiratory disease: a meta-analysis evaluating prevalence, mean provocative dose of aspirin and increased asthma morbidity

    Morales, D. R., Guthrie, B., Lipworth, B. J., Jackson, C., Donnan, P. T. & Santiago, V. H. Jul 2015 In : Allergy. 70, 7, p. 828-835 8 p.

    Research output: Contribution to journalArticle

  11. Erratum: Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis

    Baldacchino, A., Arbuckle, K., Petrie, D. J. & McCowan, C. 25 Jun 2015 In : BMC Psychiatry. 15, 4 p., 134

    Research output: Contribution to journalArticle

  12. Quantifying the cadence of free-living walking using event-based analysis

    Granat, M., Clarke, C., Holdsworth, R., Stansfield, B. & Dall, P. 1 Jun 2015 In : Gait & Posture. 42, 1, p. 85-90 6 p.

    Research output: Contribution to journalArticle

  13. A classification of chronic pain for ICD-11

    Smith, B. H. & 21 others Treede, R-D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., Giamberardino, M. A., Kaasa, S., Kosek, E., Lavandʼhomme, P., Nicholas, M., Perrot, S., Scholz, J., Schug, S., Svensson, P., Vlaeyen, J. W. S. & Wang, S-J. Jun 2015 In : PAIN. 156, 6, p. 1003-1007 5 p.

    Research output: Contribution to journalArticle

  14. Efficacy and safety of the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab among high cardiovascular risk patients on maximally tolerated statin therapy: the ODYSSEY COMBO I study

    Kereiakes, D. J., Robinson, J. G., Cannon, C. P., Lorenzato, C., Pordy, R., Chaudhari, U. & Colhoun, H. M. Jun 2015 In : American Heart Journal. 169, 6, p. 906-915 10 p.

    Research output: Contribution to journalArticle

  15. Individual variability analysis of fluorescence parameters measured in skin with different levels of nutritive blood flow

    Dunaev, A. V., Dremin, V. V., Zherebtsov, E. A., Rafailov, I. E., Litvinova, K. S., Palmer, S. G., Stewart, N. A., Sokolovski, S. G. & Rafailov, E. U. Jun 2015 In : Medical Engineering & Physics. 37, 6, p. 574-583 10 p.

    Research output: Contribution to journalArticle

  16. Cognitive behaviour therapy plus aerobic exercise training to increase activity in patients with myotonic dystrophy type 1 (DM1) compared to usual care (OPTIMISTIC): Study protocol for randomised controlled trial

    Donnan, P. & 56 others van Engelen, B., Abghari, S., Aschrafi, A., Bouman, S., Cornelissen, Y., Glennon, J., Groot, P., Heerschap, A., Heskamp, L., Heskes, T., Kapusta, K., Klerks, E., Knoop, H., Maas, D., Okkersen, K., Poelmans, G., Rahmadi, R., van Nimwegen, M., Gorman, G., Moreno, C. J., Lochmüller, H., Trenell, M., van Laar, S., Wood, L., Schoser, B., Wenninger, S., Schüller, A., Auguston, R., Baptiste, L., Barau, C., Bassez, G., Chevalier, P., Couppey, F., Delmas, S., Deux, J. F., Dogan, C., Hamadouche, A., Hankiewicz, K., Lhermet, L., Minier, L., Rialland, A., Schmitz, D., Monckton, D. G., Cumming, S. A., Adam, B., Hannah, M., Hogarth, F., Littleford, R., McKenzie, E., Rauchhaus, P., Wilkie, E., Williamson, J., Catt, M., Dittrich, J., Schwalber, A. & Treweek, S. 23 May 2015 In : Trials. 16, 224, 19 p., 224

    Research output: Contribution to journalArticle

  17. Mosaic structural variation in children with developmental disorders

    Smith, B. H. & 28 others King, D. A., Jones, W. D., Crow, Y. J., Dominiczak, A. F., Foster, N. A., Gaunt, T. R., Harris, J., Hellens, S. W., Homfray, T., Innes, J., Jones, E. A., Joss, S., Kulkarni, A., Mansour, S., Morris, A. D., Parker, M. J., Porteous, D. J., Shihab, H. A., Tatton-Brown, K., Tolmie, J. L., Trzaskowski, M., Vasudevan, P. C., Wakeling, E., Wright, M., Plomin, R., Timpson, N. J., Hurles, M. E. & The Deciphering Developmental Disorders Study 15 May 2015 In : Human Molecular Genetics. 24, 10, p. 2733-2745 13 p.

    Research output: Contribution to journalArticle

  18. The PRECIS-2 tool: designing trials that are fit for purpose

    Loudon, K., Treweek, S., Sullivan, F., Donnan, P., Thorpe, K. E. & Zwarenstein, M. 8 May 2015 In : British Medical Journal. 350, 11 p., h2147

    Research output: Contribution to journalArticle

  19. Defining analytical performance specifications: consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine

    Sandberg, S., Fraser, C. G., Horvath, A. R., Jansen, R., Jones, G., Oosterhuis, W., Petersen, P. H., Schimmel, H., Sikaris, K. & Panteghini, M. May 2015 In : Clinical Chemistry and Laboratory Medicine. 53, 6, p. 833-835 3 p.

    Research output: Contribution to journalArticle

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