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  1. Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden

    Gallacher, K. I., Batty, G., McLean, G., Mercer, S. W., Guthrie, B., May, C. R., Langhorne, P. & Mair, F. S. 3 Oct 2014 In : BMC Medicine. 12, 1, p. 151

    Research output: Contribution to journalArticle

  2. NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

    South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M. Oct 2014 In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638

    Research output: Contribution to journalArticle

  3. Does a history of depression actually mediate smoking-related pain?: findings from a cross-sectional general population-based study

    van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H. Oct 2014 In : European Journal of Pain. 18, 9, p. 1223-1230 8 p.

    Research output: Contribution to journalArticle

  4. Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?

    Torrance, N., Lawson, K. D., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H. Oct 2014 In : PAIN. 155, 10, p. 1996-2004

    Research output: Contribution to journalArticle

  5. Standard cardiovascular disease risk algorithms underestimate the risk of cardiovascular disease in schizophrenia: evidence from a national primary care database

    McLean, G., Martin, J. L., Martin, D. J., Guthrie, B., Mercer, S. W. & Smith, D. J. Oct 2014 In : Schizophrenia Research. 159, 1, p. 176-181 6 p.

    Research output: Contribution to journalArticle

  6. Valuation of hospital bed-days released by infection control programs: a comparison of methods

    Stewardson, A. J., Harbarth, S., Graves, N. & TIMBER Study Group Oct 2014 In : Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America. 35, 10, p. 1294-1297 4 p.

    Research output: Contribution to journalArticle

  7. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

    Smith, B. H. & 58 others Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., Leeuw, C. D., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J., van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D. 23 Sep 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794 5 p.

    Research output: Contribution to journalArticle

  8. An approach for utilizing clinical statements in HL7 RIM to evaluate eligibility criteria

    Bache, R., Daniel, C., James, J., Hussain, S., McGilchrist, M., Delaney, B. & Taweel, A. 1 Sep 2014

    Research output: Contribution to conferencePaper

  9. Malignancy-associated hyperamylasaemia

    Srivastava, R., Murphy, M. J. & Fraser, C. G. Sep 2014 In : Annals of Clinical Biochemistry. 51, 5, p. 619 1 p.

    Research output: Contribution to journalLetter

  10. Monotherapy with the PCSK9 inhibitor alirocumab versus ezetimibe in patients with hypercholesterolemia: Results of a 24week, double-blind, randomized Phase 3 trial

    Roth, E. M., Taskinen, M-R., Ginsberg, H. N., Kastelein, J. J. P., Colhoun, H. M., Robinson, J. G., Merlet, L., Pordy, R. & Baccara-Dinet, M. T. Sep 2014 In : International Journal of Cardiology. 176, 1, p. 55-61 7 p.

    Research output: Contribution to journalArticle

  11. Faecal haemoglobin concentrations vary with sex and age, but data are not transferable across geography for colorectal cancer screening

    Fraser, C. G., Rubeca, T., Rapi, S., Chen, L-S. & Chen, H-H. Aug 2014 In : Clinical Chemistry and Laboratory Medicine. 52, 8, p. 1211-6 6 p.

    Research output: Contribution to journalArticle

  12. Microvascular decompression for superior oblique myokymia: case report

    Fam, M. D., Scott, C., Forster, A. & Kamel, M. H. Aug 2014 In : British Journal of Neurosurgery. 28, 4, p. 552-5 4 p.

    Research output: Contribution to journalArticle

  13. The influence of socioeconomic deprivation on multimorbidity at different ages: a cross-sectional study

    McLean, G., Gunn, J., Wyke, S., Guthrie, B., Watt, G. C. M., Blane, D. N. & Mercer, S. W. 1 Jul 2014 In : British Journal of General Practice. 64, 624, p. e440-e447

    Research output: Contribution to journalArticle

  14. Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Smith, B. H. & 159 others Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H., Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., Vonk, J. M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., Postma, D. S., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y-M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O'Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., Starr, J. M., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., Burkart, K. M., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, O. D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Generation Scotland, Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Jarvelin, M-R., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., Verhamme, F. M., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J. Jul 2014 In : Nature Genetics. 46, 7, p. 669-677 9 p.

    Research output: Contribution to journalArticle

  15. Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

    Norsworthy, P. J., Vandrovcova, J., Thomas, E. R. A., Campbell, A., Kerr, S. M., Biggs, J., Game, L., Soutar, A. K., Smith, B. H., Dominiczak, A. F., Porteous, D. J., Morris, A. D., Generation Scotland & Aitman, T. J. 23 Jun 2014 In : BMC Medical Genetics. 15, 7 p.70

    Research output: Contribution to journalArticle

  16. A hard pill to swallow: a qualitative study of women's experiences of adjuvant endocrine therapy for breast cancer

    Harrow, A., Dryden, R., McCowan, C., Radley, A., Parsons, M., Thompson, A. M. & Wells, M. 12 Jun 2014 In : BMJ Open. 4, 6, 11 p.e005285

    Research output: Contribution to journalArticle

  17. Prediction of liver disease in patients whose liver function tests have been checked in primary care: model development and validation using population-based observational cohorts

    McLernon, D. J., Donnan, P. T., Sullivan, F. M., Roderick, P., Rosenberg, W. M., Ryder, S. D. & Dillon, J. F. 2 Jun 2014 In : BMJ Open. 4, 6, 10 p.e004837

    Research output: Contribution to journalArticle

  18. 60 insulin resistance is associated with all-cause mortality and accelerates the risk of progression to diabetes in non-diabetic heart failure patients

    Mohan, M., Deshmukh, H., Maria Choy, A. & Lang, C. Jun 2014 In : Heart. 100 , s3, p. A34 1 p.

    Research output: Contribution to journalMeeting abstract

  19. A summary of the Iodine Supplementation Study Protocol (I2S2): a UK multicentre randomised controlled trial in preterm infants

    Kayleigh, M. & I2S2 team Jun 2014 In : Neonatology. 105, 4, p. 282-289 8 p.

    Research output: Contribution to journalArticle

  20. Comparative cancer survival in European countries

    Munro, A. J. Jun 2014 In : British Medical Bulletin. 110, 1, p. 5-22 18 p.

    Research output: Contribution to journalArticle

  21. Effectiveness of newspaper advertising for patient recruitment into a clinical trial

    Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S. Jun 2014 In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

    Research output: Contribution to journalArticle

  22. Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008

    Jones, N. R. V., Fischbacher, C. M., Guthrie, B., Leese, G., Lindsay, R. S., McKnight, J. A., Pearson, D., Philip, S., Sattar, N., Wild, S. H. & Scottish Diabetes Research Network Epidemiology Group Jun 2014 In : Diabetic Medicine. 31, 6, p. 640-646 7 p.

    Research output: Contribution to journalArticle

  23. Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

    Zhou, K., Donnelly, L., Yang, J., Li, M., Deshmukh, H., Van Zuydam, N., Ahlqvist, E., Spencer, C. C., Groop, L., Morris, A. D., Colhoun, H. M., Sham, P. C., McCarthy, M. I., Palmer, C. N. A. & Pearson, E. R. Jun 2014 In : The Lancet Diabetes and Endocrinology. 2, 6, p. 481-487 7 p.

    Research output: Contribution to journalArticle

  24. Contemporary risk of hip fracture in type 1 and type 2 diabetes: a national registry study from Scotland

    Hothersall, E. J., Livingstone, S. J., Looker, H. C., Ahmed, S. F., Cleland, S., Leese, G. P., Lindsay, R. S., McKnight, J., Pearson, D., Philip, S., Wild, S. H. & Colhoun, H. M. May 2014 In : Journal of Bone and Mineral Research. 29, 5, p. 1054-1060 7 p.

    Research output: Contribution to journalArticle

  25. A gender-sensitised weight loss and healthy living programme for overweight and obese men delivered by Scottish Premier League football clubs (FFIT): a pragmatic randomised controlled trial

    Hunt, K., Wyke, S., Gray, C. M., Anderson, A. S., Brady, A., Bunn, C., Donnan, P. T., Fenwick, E., Grieve, E., Lieshman, J., Miller, E., Mutrie, N., Rauchhaus, P., White, A. & Treweek, S. 5 Apr 2014 In : Lancet. 383, 9924, p. 1211-1221 11 p.

    Research output: Contribution to journalArticle

  26. Neuropathic pain in the general population: a systematic review of epidemiological studies

    van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N. Apr 2014 In : PAIN. 155, 4, p. 654-662

    Research output: Contribution to journalArticle

  27. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  28. A standard for Faecal Immunochemical TesTs for Haemoglobin Evaluation Reporting (FITTER)

    Fraser, C. G., Allison, J. E., Young, G. P., Halloran, S. P. & Seaman, H. Mar 2014 In : Annals of Clinical Biochemistry. 51, 2, p. 301-302 2 p.

    Research output: Contribution to journalLetter

  29. Paper-based and web-based Intervention modelling experiments identified the same predictors of general practitioner antibiotic prescribing behavior

    Treweek, S., Bonetti, D., MacLennan, G., Barnett, K., Eccles, M. P., Jones, C., Pitts, N. B., Ricketts, I. W., Sullivan, F., Weal, M. & Francis, J. J. Mar 2014 In : Journal of Clinical Epidemiology. 67, 3, p. 296-304 9 p.

    Research output: Contribution to journalArticle

  30. Population screening for colorectal cancer means getting FIT: the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT)

    Allison, J. E., Fraser, C. G., Halloran, S. P. & Young, G. P. Mar 2014 In : Gut and Liver. 8, 2, p. 117-130 14 p.

    Research output: Contribution to journalArticle

  31. CRIB - the use of cardiac rehabilitation services to aid the recovery of patients with bowel cancer: a pilot randomised controlled trial (RCT) with embedded feasibility study

    Munro, J., Adams, R., Campbell, A., Campbell, S., Donaldson, C., Godwin, J., Haw, S., Kidd, L., Lane, C., Leslie, S. J., Mason, H., Mutrie, N., O'Carroll, R., Taylor, C., Treweek, S., Watson, A. & Hubbard, G. 18 Feb 2014 In : BMJ Open. 4, 2, e004684

    Research output: Contribution to journalArticle

  32. The Kuwait-Scotland eHealth Innovation Network (KSeHIN): a sustainable approach to quality improvement in healthcare

    Conway, N. T. , Connell, J. , Morris, A. & 21 others Wotayan, R. A., Alkuzam, A., Al-Refaei, F. F., Badawi, D., Barake, R., Bell, A., Boyle, G., Chisholm, S., Emslie-Smith, A., Goddard, C. A., Greene, S. A., Halawa, N., Judson, A., Kelly, C., Ker, J., Scott, M., Shaltout, A., Sukkar, F., Wake, D., Sibbald, D. & Behbehani, K. Feb 2014 In : Quality in Primary Care. 22, 1, p. 43-51 9 p.

    Research output: Contribution to journalArticle

  33. Developing a complex intervention to improve prescribing safety in primary care: mixed methods feasibility and optimisation pilot study

    Grant, A. M., Guthrie, B. & Dreischulte, T. 21 Jan 2014 In : BMJ Open. 4, 1, 8 p.e004153

    Research output: Contribution to journalArticle

  34. The prognostic value of pre-operative and post-operative B-type natriuretic peptides in patients undergoing noncardiac surgery: B-type natriuretic peptide and N-terminal fragment of pro-B-type natriuretic peptide: a systematic review and individual patient data meta-analysis

    Rodseth, R. N. , Biccard, B. M. , Le Manach, Y. , Sessler, D. I. , Lurati Buse, G. A. , Thabane, L. , Schutt, R. C. , Bolliger, D. , Cagini, L. , Cardinale, D. , Chong, C. P. W. , Chu, R. , Cnotliwy, M. , Di Somma, S. , Fahrner, R. , Lim, W. K. , Mahla, E. , Manikandan, R. , Puma, F. , Pyun, W. B. & 7 others Radović, M., Rajagopalan, S., Suttie, S., Vanniyasingam, T., van Gaal, W. J., Waliszek, M. & Devereaux, P. J. 21 Jan 2014 In : Journal of the American College of Cardiology. 63, 2, p. 170-180 11 p.

    Research output: Contribution to journalArticle

  35. Identifying which septic patients have increased mortality risk using severity scores: a cohort study

    Marwick, C. A., Guthrie, B., Pringle, J. E., McLeod, S. R., Evans, J. M. & Davey, P. G. 2 Jan 2014 In : BMC Anesthesiology. 14, 1, p. 1

    Research output: Contribution to journalArticle

  36. NSAIDs and cardiovascular risk

    Bell, S. & Marwick, C. A. Jan 2014 In : Kidney International. 85, 1, p. 211 1 p.

    Research output: Contribution to journalLetter

  37. Patterns of uptake in a biennial faecal occult blood test screening programme for colorectal cancer

    Steele, R. J. C., McClements, P. L., Libby, G., Carey, F. A. & Fraser, C. . G. Jan 2014 In : Colorectal Disease. 16, 1, p. 28-32 5 p.

    Research output: Contribution to journalArticle

  38. Risk stratification for diabetic eye screening. Reply to Stratton I. M. and Aldington S. J. [letter]

    Looker, H. C., Nyangoma, S. O., Cromie, D. T., Olson, J. A., Leese, G. P., Philip, S., Black, M. W., Doig, J., Lee, N., Briggs, A., Hothersall, E. J., Morris, A. D., Lindsay, R. S., McKnight, J. A., Pearson, D. W. M., Sattar, N. A., Wild, S. H., McKeigue, P., Colhoun, H. M. & on behalf of the Scottish Diabetes Research Network Epidemiology Group and the Scottish Diabetic Retinopathy Collaborative Jan 2014 In : Diabetologia. 57, 1, p. 260-261 2 p.

    Research output: Contribution to journalLetter

  39. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol

    Holt, A-M., Jancey, J., Lee, A. H., Kerr, D. A., Hills, A. P., Anderson, A. S. & Howat, P. A. 2014 In : BMJ Open. 4, 9, p. e005107

    Research output: Contribution to journalArticle

  40. A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain

    Meng, W., Deshmukh, H. A., van Zuydam, N. R., Liu, Y., Donnelly, L. A., Zhou, K., Morris, A. D., Colhoun, H. M., Palmer, C. N. A., Smith, B. H., Wellcome Trust Case Control Consortium 2 (WTCCC2) & Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group 2014 In : European Journal of Pain.

    Research output: Contribution to journalArticle

  41. A rare cause of massive haematuria: Internal iliac artery-ureteric fistula

    Rao, A. M., Khalil, A. & Suttie, S. 2014 In : Vascular Medicine.

    Research output: Contribution to journalArticle

  42. A study of National Health Service management of chronic osteoarthritis and low back pain

    Hart, O. R., Uden, R. M., McMullan, J. E., Ritchie, M. S., Williams, T. D. & Smith, B. H. 2014 In : Primary Health Care Research and Development. 10 p.

    Research output: Contribution to journalArticle

  43. A survey of reporting of colorectal cancer in Scotland: compliance with guidelines and effect of proforma reporting

    Woods, Y. L., Mukhtar, S., McClements, P., Lang, J., Steele, R. J. & Carey, F. A. 2014 In : Journal of Clinical Pathology. 67, p. 499-505 7 p.

    Research output: Contribution to journalArticle

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