Division of Population Health Sciences

Can pragmatic trials help us better understand chronic pain and improve treatment?

Rowbotham, M. C., Gilron, I., Glazer, C., Rice, A. S. C., Smith, B. H., Stewart, W. F. & Wasan, A. D. May-2013 In : PAIN. 154, 5, p. 643-646, 4 p.

Research output: Contribution to journal › Article

Laparoscopic Surgical Skills are Significantly Improved by the Use of a Portable Laparoscopic Simulator: Results of a Randomized Controlled Trial

Johnston, T. J., Tang, B., Alijani, A., Tait, I., Steele, R. J., Ker, J., Nabi, G. & Surgical Simulation Group at the University of Dundee May-2013 In : World Journal of Surgery. 37, 5, p. 957-964, 8 p.

Research output: Contribution to journal › Article

Neuropathic pain in the community: more under-treated than refractory?

Torrance, N., Ferguson, J. A., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H. May-2013 In : PAIN. 154, 5, p. 690–699, 10 p.

Research output: Contribution to journal › Article

Schizophrenia is associated with excess multiple physical-health comorbidities but low levels of recorded cardiovascular disease in primary care: cross-sectional study

Smith, D. J., Langan, J., McLean, G., Guthrie, B. & Mercer, S. W. 17-Apr-2013 In : BMJ Open. 3, 4, e002808

Research output: Contribution to journal › Article

Pharmacist-led management of chronic pain in primary care: results from a randomised controlled exploratory trial

Bruhn, H., Bond, C. M., Elliott, A. M., Hannaford, P. C., Lee, A. J., McNamee, P., Smith, B. H., Watson, M. C., Holland, R. & Wright, D. 5-Apr-2013 In : BMJ Open. 3, 4, e002361

Research output: Contribution to journal › Article

Cost-effectiveness of self-management methods for the treatment of chronic pain in an aging adult population: a systematic review of the literature

Boyers, D., McNamee, P., Clarke, A., Jones, D., Martin, D., Schofield, P. & Smith, B. H. Apr-2013 In : Clinical Journal of Pain. 29, 4, p. 366-375, 10 p.

Research output: Contribution to journal › Article

Trimethoprim prescription and subsequent resistance in childhood urinary infection: multilevel modelling analysis

Duffy, M. A., Hernandez-Santiago, V., Orange, G., Davey, P. G. & Guthrie, B. Apr-2013 In : British Journal of General Practice. 63, 609, p. 238-43, 6 p.

Research output: Contribution to journal › Article

Obesity and lifestyle advice in colorectal cancer survivors - How well are clinicians prepared?

Anderson, A. S., Caswell, S., Wells, M. & Steele, R. J. C. 9-Mar-2013 In : Colorectal Disease. 15 p.

Research output: Contribution to journal › Article

Diabetes and schizophrenia: exploring the associations: determining the extent of diabetes and the quality of diabetes care within a clozapine (schizophrenia) clinic in Edinburgh

Perera, S. M., Cochrane, L., Wang, Y., MacIntyre, D. J. & Wake, D. Mar-2013 In : Diabetic Medicine. 30, Suppl. 1, p. 180-181, 2 p., P506

Research output: Contribution to journal › Meeting abstract

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

Smith, B. H. & 51 others Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M., Jameson, K. A., Jones, G. T., Launer, L. J., Kerkhof, H. J. M., De Kruijf, M., McBeth, J., Kloppenburg, M., Ollier, W. E., Oostra, B., Payton, A., Rivadeneira, F., Smith, A. V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A. G., Wang, K., Van Wingerden, S. H., Arden, N. K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G. J., Pendleton, N., Slagboom, P. E., Spector, T. D., Völzke, H., Kavelaars, A., Van Duijn, C. M., Williams, F. M. K. & Van Meurs, J. B. J. Mar-2013 In : Annals of the Rheumatic Diseases. 72, 3, p. 427-436, 10 p.

Research output: Contribution to journal › Article

Lessons from Mackenzie that still resonate

Van Hecke, O., Smith, B. H. & Sullivan, F. M. Mar-2013 In : British Journal of General Practice. 63, 608, p. 158-159, 2 p.

Research output: Contribution to journal › Comment/debate

Thyroid testing in pregnant women with thyroid dysfunction in Tayside, Scotland: the thyroid epidemiology, audit and research study (TEARS)

Vadiveloo, T., Mires, G. J., Donnan, P. T. & Leese, G. P. Mar-2013 In : Clinical Endocrinology. 78, 3, p. 466-71, 6 p.

Research output: Contribution to journal › Article

Transrectal quantitative shear wave elastography in the detection and characterisation of prostate cancer

Ahmad, S., Cao, R., Varghese, T., Bidaut, L. & Nabi, G. Mar-2013 In : Surgical Endoscopy. p. 1-8, 8 p.

Research output: Contribution to journal › Article

Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality

McCowan, C., Munro, A. J., Donnan, P. T. & Steele, R. J. C. Mar-2013 In : European Journal of Cancer. 49, 5, p. 1049-1057, 9 p.

Research output: Contribution to journal › Article

Long-acting β-agonist prescribing in people with asthma in primary care

Morales, D. R., Jackson, C., Fielding, S. & Guthrie, B. 1-Feb-2013 In : Thorax. 68, 2, p. 192-194, 3 p.

Research output: Contribution to journal › Article

Maternal and umbilical cord levels of T4, TSH, TPOAb and TGAb in term infants and neurodevelopmental outcome at 5.5 years.

Williams, F. L. R., Watson, J., Ogston, S. A., Visser, T. J., Hume, R. & Willatts, P. 1-Feb-2013 In : Journal of Clinical Endocrinology and Metabolism. p. 829-838

Research output: Contribution to journal › Article

Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes

Alkayyali, S., Lajer, M., Deshmukh, H., Ahlqvist, E., Colhoun, H., Isomaa, B., Rossing, P., Groop, L. & Lyssenko, V. Feb-2013 In : Diabetologia. 56, 2, p. 323-329, 7 p.

Research output: Contribution to journal › Article

An observational study of psychotropic drug use and initiation in older patients resident in their own home or in care

McCowan, C., Magin, P., Clark, S. & Guthrie, B. 1-Jan-2013 In : Age and Ageing. 42, 1, p. 51-56, 6 p.

Research output: Contribution to journal › Article

Pioglitazone and bladder cancer: A propensity score matched cohort study

Wei, L., Macdonald, T. M. & Mackenzie, I. S. Jan-2013 In : British Journal of Clinical Pharmacology. 75, 1, p. 254-259, 6 p.

Research output: Contribution to journal › Article

Age- and gender-specific TSH reference intervals in people with no obvious thyroid disease in Tayside, Scotland: the thyroid epidemiology, audit, and research study (TEARS)

Vadiveloo, T., Donnan, P. T., Murphy, M. J. & Leese, G. P. 2013 In : Journal of Clinical Endocrinology & Metabolism. 98, 3, p. 1147-1153, 7 p.

Research output: Contribution to journal › Article

Community acquired infections in older patients admitted to hospital from care homes versus the community: cohort study of microbiology and outcomes

Marwick, C., Hernandez Santiago, V., McCowan, C., Broomhall, J. & Davey, P. 2013 In : BMC Geriatrics. 13, 12

Research output: Contribution to journal › Article

External validity of randomized controlled trials of glycaemic control and vascular disease: how representative are participants?

Guthrie, B. & 25 others Saunders, C., Byrne, C. D., Lindsay, R. S., Mcknight, J. A., Philip, S., Sattar, N., Walker, J. J., Wild, S. H., Brady, I., Chalmers, J., Colhoun, H., Cunningham, S., Elder, R., Emslie-Smith, A., Fischbacher, C., Govan, L., Jones, N., Leese, G., Levine, D., Livingstone, S., Looker, H., McAlpine, R., Morris, A., Pearson, D. & Petrie, J. 2013 In : Diabetic Medicine. 30, 3, p. 300-308, 9 p.

Research output: Contribution to journal › Article

Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity

Hughes, L. D., McMurdo, M. E. T. & Guthrie, B. 2013 In : Age and Ageing. 42, 1, p. 62-69, 8 p.

Research output: Contribution to journal › Article

Methodology of a large prospective, randomised, open, blinded endpoint streamlined safety study of celecoxib versus traditional non-steroidal anti-inflammatory drugs in patients with osteoarthritis or rheumatoid arthritis: protocol of the standard care versus celecoxib outcome trial (SCOT)

MacDonald, T. M., Mackenzie, I. S., Wei, L., Hawkey, C. J. & Ford, I. 2013 In : BMJ Open. 3, 1, 8 p., e002295

Research output: Contribution to journal › Article

Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis

Treweek, S., Lockhart, P., Pitkethly, M., Cook, J., Kjeldstrom, M., Johansen, M., Taskila, T., Sullivan, F., Wilson, S., Jackson, C., Jones, R. & Mitchell, E. 2013 In : BMJ Open. 3, 2, p. 1-24, 24 p.

Research output: Contribution to journal › Article

Morbidity experienced by women before and after operative vaginal delivery: prospective cohort study nested within a two-centre RCT of restrictive versus routine use of episiotomy

Macleod, M. 2013 In : BJOG: An International Journal of Obstetrics & Gynaecology.

Research output: Contribution to journal › Article

Outcomes of total hip arthroplasty in the octogenarian population

Kennedy, J. W., Johnston, L., Cochrane, L. & Boscainos, P. J. 2013 In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland.

Research output: Contribution to journal › Article

Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study

Kerr, S. M., Campbell, A., Murphy, L., Hayward, C., Jackson, C., Wain, L. V., Tobin, M. D., Dominiczak, A., Morris, A., Smith, B. H. & Porteous, D. J. 2013 In : BMC Medical Genetics. 14, 38

Research output: Contribution to journal › Article

Process evaluations for cluster-randomised trials of complex interventions: a proposed framework for design and reporting

Grant, A., Treweek, S., Dreischulte, T., Foy, R. & Guthrie, B. 2013 In : Trials. 14, 20 p., 15

Research output: Contribution to journal › Article

The effect of physical multimorbidity, mental health conditions and socioeconomic deprivation on unplanned admissions to hospital: a retrospective cohort study

Payne, R. A., Abel, G. A., Guthrie, B. & Mercer, S. W. 2013 In : CMAJ. 185, 5, 8 p.

Research output: Contribution to journal › Article

Tissue mimicking materials for the detection of prostate cancer using shear wave elastography: A validation study

Cao, R., Huang, Z., Varghese, T. & Nabi, G. 2013 In : Medical Physics. 40, 2, p. 022903

Research output: Contribution to journal › Article

What predicts adverse outcomes in untreated primary hyperparathyroidism?: The Parathyroid Epidemiology and Audit Research Study (PEARS)

Yu, N., Leese, G. P. & Donnan, P. T. 2013 In : Clinical Endocrinology.

Research output: Contribution to journal › Article

Can text messages reach the parts other process measures cannot reach: an evaluation of a behavior change intervention delivered by mobile phone?

Irvine, L., Falconer, D. W., Jones, C., Ricketts, I. W., Williams, B. & Crombie, I. K. 26-Dec-2012 In : PLoS ONE. 7, 12, p. e52621

Research output: Contribution to journal › Article

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

Chasman, D. I. , Fuchsberger, C. , Pattaro, C. , Teumer, A. , Boeger, C. A. , Endlich, K. , Olden, M. , Chen, M-H. , Tin, A. , Taliun, D. , Li, M. , Gao, X. , Gorski, M. , Yang, Q. , Hundertmark, C. , Foster, M. C. , O'Seaghdha, C. M. , Glazer, N. , Isaacs, A. , Liu, C-T. & 148 others Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M. F., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Toenjes, A., Dehghan, A., Lambert, J-C., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimaeki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Coassin, S., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Giulianini, F., Koenig, W., Illig, T., Meisinger, C., Gieger, C., Zgaga, L., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Noethlings, U., Jacobs, G., Biffar, R., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Voelker, U., Voelzke, H., Kovacs, P., Stumvoll, M., Maegi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Stengel, B., Ruggiero, D., Bergmann, S., Kahonen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Kraemer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G-A., Paulweber, B., Haun, M., Sala, C., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I. B., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J., Hayward, C., Ridker, P. M., Parsa, A., Bochud, M., Heid, I. M., Kao, W. H. L., Fox, C. S., Koettgen, A., CARDIoGRAM Consortium, ICBP Consortium, CARe Consortium & WTCCC2 15-Dec-2012 In : Human Molecular Genetics. 21, 24, p. 5329-5343, 15 p.

Research output: Contribution to journal › Article

The Utility of Liver Function Tests for Mortality Prediction within One Year in Primary Care Using the Algorithm for Liver Function Investigations (ALFI)

McLernon, D. J., Dillon, J. F., Sullivan, F. M., Donnan, P. T., Roderick, P., Rosenberg, W. M. & Ryder, S. D. 14-Dec-2012 In : PLoS ONE. 7, 12, e50965

Research output: Contribution to journal › Article

Selective sampling using confocal Raman spectroscopy provides enhanced specificity for urinary bladder cancer diagnosis

Barman, I., Dingari, N. C., Singh, G. P., Kumar, R., Lang, S. & Nabi, G. 1-Dec-2012 In : Analytical and Bioanalytical Chemistry. 404, 10, p. 3091-3099, 9 p.

Research output: Contribution to journal › Article

Can theory be embedded in visual interventions to promote self-management?: a proposed model and worked example

Williams, B., Anderson, A. S., Barton, K. & McGhee, J. Dec-2012 In : International Journal of Nursing Studies. 49, 12, p. 1598-1609, 12 p.

Research output: Contribution to journal › Article

Needle Embolisation to the Right Ventricle: Multiple Complications in a Complex Patient

Moussa, O., Mittapalli, D. & Suttie, S. Dec-2012 In : EJVES Extra. 24, 6, p. e39-e40, 2 p.

Research output: Contribution to journal › Article

Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: A nationwide study

Kennon, B., Leese, G. P., Cochrane, L., Colhoun, H., Wild, S., Stang, D., Sattar, N., Pearson, D., Lindsay, R. S., Morris, A. D., Livingstone, S., Young, M., McKnight, J. & Cunningham, S. Dec-2012 In : Diabetes Care. 35, 12, p. 2588-2590, 3 p.

Research output: Contribution to journal › Article

A future for faecal haemoglobin measurements in the medical laboratory

Fraser, C. G. Nov-2012 In : Annals of Clinical Biochemistry. 49, 6, p. 518-526, 9 p.

Research output: Contribution to journal › Article

Adapting clinical guidelines to take account of multimorbidity

Guthrie, B., Payne, K., Alderson, P., McMurdo, M. E. T. & Mercer, S. W. 4-Oct-2012 In : British Medical Journal. 345, p. -, 5 p., e6341

Research output: Contribution to journal › Article

Epidemiology of multimorbidity: authors' reply

Guthrie, B., Watt, G., Wyke, S. & Mercer, S. W. 1-Oct-2012 In : Lancet. 380, 9851, p. 1383-1384, 2 p.

Research output: Contribution to journal › Article

Antifungal therapy in European hospitals: data from the ESAC point-prevalence surveys 2008 and 2009

ESAC-3 Hosp Care Subproject Grp Oct-2012 In : Clinical Microbiology and Infection. 18, 10, p. E389-E395, 7 p.

Research output: Contribution to journal › Article

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

Sandholm, N. , Salem, R. M. , McKnight, A. J. , Brennan, E. P. , Forsblom, C. , Isakova, T. , McKay, G. J. , Williams, W. W. , Sadlier, D. M. , Makinen, V-P. , Swan, E. J. , Palmer, C. , Boright, A. P. , Ahlqvist, E. , Deshmukh, H. A. , Keller, B. J. , Huang, H. , Ahola, A. J. , Fagerholm, E. , Gordin, D. & 73 others Harjutsalo, V., He, B., Heikkila, O., Hietala, K., Kyto, J., Lahermo, P., Lehto, M., Lithovius, R., Osterholm, A-M., Parkkonen, M., Pitkaniemi, J., Rosengard-Barlund, M., Saraheimo, M., Sarti, C., Soderlund, J., Soro-Paavonen, A., Syreeni, A., Thorn, L. M., Tikkanen, H., Tolonen, N., Tryggvason, K., Tuomilehto, J., Waden, J., Gill, G. V., Prior, S., Guiducci, C., Mirel, D. B., Taylor, A., Hosseini, S. M., Parving, H-H., Rossing, P., Tarnow, L., Ladenvall, C., Alhenc-Gelas, F., Lefebvre, P., Rigalleau, V., Roussel, R., Tregouet, D-A., Maestroni, A., Maestroni, S., Falhammar, H., Gu, T., Mollsten, A., Cimponeriu, D., Ioana, M., Mota, M., Mota, E., Serafinceanu, C., Stavarachi, M., Hanson, R. L., Nelson, R. G., Kretzler, M., Colhoun, H. M., Panduru, N. M., Gu, H. F., Brismar, K., Zerbini, G., Hadjadj, S., Marre, M., Groop, L., Lajer, M., Bull, S. B., Waggott, D., Paterson, A. D., Savage, D. A., Bain, S. C., Martin, F., Hirschhorn, J. N., Godson, C., Florez, J. C., Groop, P-H., Maxwell, A. P. & DCCT-EDIC Res Grp 20-Sep-2012 In : PLoS Genetics. 8, 9, 13 p., e1002921

Research output: Contribution to journal › Article

Learning curves, taking instructions, and patient safety: using a theoretical domains framework in an interview study to investigate prescribing errors among trainee doctors

Duncan, E. M., Francis, J. J., Johnston, M., Davey, P., Maxwell, S., McKay, G. A., McLay, J., Ross, S., Ryan, C., Webb, D. J., Bond, C. & PROTECT Study Group 11-Sep-2012 In : Implementation Science. 7, 27 p., 86

Research output: Contribution to journal › Article

A minimally invasive temporary cavernoso-saphenous shunt in the management of priapism after failed conservative treatment

Mains, E., Aboumarzouk, O., Ahmad, S., El-Mokadem, I. & Nabi, G. Sep-2012 In : Minimally Invasive Therapy & Allied Technologies. 21, 5, p. 366-368, 3 p.

Research output: Contribution to journal › Article

Audit of Staphylococcus aureus bacteraemia management in NHS Tayside and comparison with European Antibiotic Strategies study group international quality standards

Johnston, T., Yeoman, T., Chapman, S., Marwick, C. & Nathwani, D. Sep-2012 In : Journal of Antimicrobial Chemotherapy. 67, 9, p. 2304-2306, 3 p.

Research output: Contribution to journal › Letter

Durability of the effect of online diabetes training for medical residents on knowledge, confidence, and inpatient glycemia

Tamler, R., Green, D. E., Skamagas, M., Breen, T. L., Lu, K., Looker, H. C., Babyatsky, M. & Leroith, D. Sep-2012 In : British Journal of Diabetes and Vascular Disease. 4, 3, p. 281-290, 10 p.

Research output: Contribution to journal › Article

Lipid-Modifying Therapies and Risk of Pancreatitis: a Meta-analysis

Preiss, D., Tikkanen, M. J., Welsh, P., Ford, I., Lovato, L. C., Elam, M. B., LaRosa, J. C., DeMicco, D. A., Colhoun, H. M., Goldenberg, I., Murphy, M. J., MacDonald, T. M., Pedersen, T. R., Keech, A. C., Ridker, P. M., Kjekshus, J., Sattar, N. & McMurray, J. J. V. 22-Aug-2012 In : JAMA: the Journal of the American Medical Association. 308, 8, p. 804-811, 8 p.

Research output: Contribution to journal › Scientific review