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Division of Population Health Sciences

  1. A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series

    Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G. Dec 2014 In : BMJ Quality & Safety. 23, 12

    Research output: Contribution to journalArticle

  2. Quality in primary care

    Guthrie, B. & Dreischulte, T. 11 Nov 2014 In : BMJ. 349, 2 p.g6485

    Research output: Contribution to journalEditorial

  3. Exploring stakeholders' views of medical education research priorities: a national survey

    Dennis, A. A., Cleland, J. A., Johnston, P., Ker, J. S., Lough, M. & Rees, C. E. Nov 2014 In : Medical Education. 48, 11, p. 1078-1091 14 p.

    Research output: Contribution to journalArticle

  4. Impact of faecal occult blood test screening on emergency admissions and short-term outcomes for colorectal cancer

    Libby, G., Brewster, D. H. & Steele, R. J. C. Nov 2014 In : British Journal of Surgery. 101, 12, p. 1607-1615 9 p.

    Research output: Contribution to journalArticle

  5. Laparoscopic nephrectomy for Adult Polycystic Kidney Disease (APKD): safety, feasibility and early outcomes

    Williamson, A., Paterson, S., Erolin, C., Sweeney, C., Townell, N. & Nabi, G. Nov 2014 In : Journal of Endourology. 28, 11, p. 1268-1277 10 p.

    Research output: Contribution to journalArticle

  6. Risk of AKI with gentamicin as surgical prophylaxis

    Bell, S., Davey, P., Nathwani, D., Marwick, C., Vadiveloo, T., Sneddon, J., Patton, A., Bennie, M., Fleming, S. & Donnan, P. T. Nov 2014 In : Journal of the American Society of Nephrology. 25, 11, p. 2625-2632 8 p.

    Research output: Contribution to journalArticle

  7. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

    Morris, A. & 103 others Postmus, I., Trompet, S., Deshmukh, H. A., Barnes, M. R., Li, X., Warren, H. R., Chasman, D. I., Zhou, K., Arsenault, B. J., Donnelly, L. A., Wiggins, K. L., Avery, C. L., Griffin, P., Feng, Q., Taylor, K. D., Li, G., Evans, D. S., Smith, A. V., de Keyser, C. E., Johnson, A. D., de Craen, A. J. M., Stott, D. J., Buckley, B. M., Ford, I., Westendorp, R. G. J., Eline Slagboom, P., Sattar, N., Munroe, P. B., Sever, P., Poulter, N., Stanton, A., Shields, D. C., O'Brien, E., Shaw-Hawkins, S., Ida Chen, Y-D., Nickerson, D. A., Smith, J. D., Pierre Dubé, M., Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, J. J. P., McKeigue, P. M., Betteridge, J., Neil, A., Durrington, P. N., Doney, A., Carr, F., McCarthy, M. I., Groop, L., Ahlqvist, E., Bis, J. C., Rice, K., Smith, N. L., Lumley, T., Whitsel, E. A., Stürmer, T., Boerwinkle, E., Ngwa, J. S., O'Donnell, C. J., Vasan, R. S., Wei, W-Q., Wilke, R. A., Liu, C-T., Sun, F., Guo, X., Heckbert, S. R., Post, W., Sotoodehnia, N., Arnold, A. M., Stafford, J. M., Ding, J., Herrington, D. M., Kritchevsky, S. B., Eiriksdottir, G., Launer, L. J., Harris, T. B., Chu, A. Y., Giulianini, F., MacFadyen, J. G., Barratt, B. J., Nyberg, F., Stricker, B. H., Uitterlinden, A. G., Hofman, A., Rivadeneira, F., Emilsson, V., Franco, O. H., Ridker, P. M., Gudnason, V., Liu, Y., Denny, J. C., Ballantyne, C. M., Rotter, J. I., Adrienne Cupples, L., Psaty, B. M., Palmer, C. N. A., Tardif, J-C., Colhoun, H. M., Hitman, G., Krauss, R. M., Wouter Jukema, J., Caulfield, M. J. & Welcome Trust Case Control Consortium 28 Oct 2014 In : Nature Communications. 5, 10 p.5068

    Research output: Contribution to journalArticle

  8. Supervised learning events in the Foundation Programme: a UK-wide narrative interview study

    Rees, C. E., Cleland, J. A., Dennis, A., Kelly, N., Mattick, K. & Monrouxe, L. V. 16 Oct 2014 In : BMJ Open. 4, 10, 14 p.e005980

    Research output: Contribution to journalArticle

  9. Effective Feedback to Improve Primary Care Prescribing Safety (EFIPPS) a pragmatic three-arm cluster randomised trial: designing the intervention (ClinicalTrials.gov registration NCT01602705)

    Barnett, K. N., Bennie, M., Treweek, S., Robertson, C., Petrie, D. J., Ritchie, L. D. & Guthrie, B. 11 Oct 2014 In : Implementation Science. 9, 10 p.133

    Research output: Contribution to journalArticle

  10. Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden

    Gallacher, K. I., Batty, G. D., McLean, G., Mercer, S. W., Guthrie, B., May, C. R., Langhorne, P. & Mair, F. S. 3 Oct 2014 In : BMC Medicine. 12, 1, 9 p.151

    Research output: Contribution to journalArticle

  11. NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis

    South, A. P., Purdie, K. J., Watt, S. A., Haldenby, S., den Breems, N., Dimon, M., Arron, S. T., Kluk, M. J., Aster, J. C., McHugh, A., Xue, D. J., Dayal, J. H. S., Robinson, K. S., Rizvi, S. M. H., Proby, C. M., Harwood, C. A. & Leigh, I. M. Oct 2014 In : Journal of Investigative Dermatology. 134, 10, p. 2630-2638

    Research output: Contribution to journalArticle

  12. Colorectal cancer screening

    Steele, R. J. C. Oct 2014 In : British Journal of Surgery. 101, 11, p. 1338-1340 3 p.

    Research output: Contribution to journalArticle

  13. Does a history of depression actually mediate smoking-related pain?: findings from a cross-sectional general population-based study

    van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H. Oct 2014 In : European Journal of Pain. 18, 9, p. 1223-1230 8 p.

    Research output: Contribution to journalArticle

  14. Efficacy and Safety of Alirocumab as Add-on Therapy in High–Cardiovascular-Risk Patients With Hypercholesterolemia Not Adequately Controlled With Atorvastatin (20 or 40 mg) or Rosuvastatin (10 or 20 mg): Design and Rationale of the ODYSSEY OPTIONS Studies

    Robinson, J. G., Colhoun, H. M., Bays, H. E., Jones, P. H., Du, Y., Hanotin, C. & Donahue, S. Oct 2014 In : Clinical Cardiology. 37, 10, p. 597-604 8 p.

    Research output: Contribution to journalArticle

  15. Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?

    Torrance, N., Lawson, K. D., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H. Oct 2014 In : PAIN. 155, 10, p. 1996-2004 9 p.

    Research output: Contribution to journalArticle

  16. Standard cardiovascular disease risk algorithms underestimate the risk of cardiovascular disease in schizophrenia: evidence from a national primary care database

    McLean, G., Martin, J. L., Martin, D. J., Guthrie, B., Mercer, S. W. & Smith, D. J. Oct 2014 In : Schizophrenia Research. 159, 1, p. 176-181 6 p.

    Research output: Contribution to journalArticle

  17. Valuation of hospital bed-days released by infection control programs: a comparison of methods

    Stewardson, A. J., Harbarth, S., Graves, N. & TIMBER Study Group Oct 2014 In : Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America. 35, 10, p. 1294-1297 4 p.

    Research output: Contribution to journalArticle

  18. A cluster-randomised controlled trial of a physical activity and nutrition programme in retirement villages: a study protocol

    Holt, A-M., Jancey, J., Lee, A. H., Kerr, D. A., Hills, A. P., Anderson, A. S. & Howat, P. A. 25 Sep 2014 In : BMJ Open. 4, 9, 8 p.e005107

    Research output: Contribution to journalArticle

  19. Chromosome 9p deletion in clear cell renal cell carcinoma predicts recurrence and survival following surgery

    El-Mokadem, I., Fitzpatrick, J., Bondad, J., Rauchhaus, P., Cunningham, J., Pratt, N., Fleming, S. & Nabi, G. 23 Sep 2014 In : British Journal of Cancer. 111, 7, p. 1381-1390 10 p.

    Research output: Contribution to journalArticle

  20. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

    Smith, B. H. & 58 others Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., Leeuw, C. D., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J., van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D. 23 Sep 2014 In : Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794 5 p.

    Research output: Contribution to journalArticle

  21. An approach for utilizing clinical statements in HL7 RIM to evaluate eligibility criteria

    Bache, R., Daniel, C., James, J., Hussain, S., McGilchrist, M., Delaney, B. & Taweel, A. 1 Sep 2014

    Research output: Contribution to conferencePaper

  22. Malignancy-associated hyperamylasaemia

    Srivastava, R., Murphy, M. J. & Fraser, C. G. Sep 2014 In : Annals of Clinical Biochemistry. 51, 5, p. 619 1 p.

    Research output: Contribution to journalLetter

  23. Monotherapy with the PCSK9 inhibitor alirocumab versus ezetimibe in patients with hypercholesterolemia: Results of a 24week, double-blind, randomized Phase 3 trial

    Roth, E. M., Taskinen, M-R., Ginsberg, H. N., Kastelein, J. J. P., Colhoun, H. M., Robinson, J. G., Merlet, L., Pordy, R. & Baccara-Dinet, M. T. Sep 2014 In : International Journal of Cardiology. 176, 1, p. 55-61 7 p.

    Research output: Contribution to journalArticle

  24. Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials

    Boekholdt, S. M. , Hovingh, G. K. , Mora, S. , Arsenault, B. J. , Amarenco, P. , Pedersen, T. R. , LaRosa, J. C. , Waters, D. D. , DeMicco, D. A. , Simes, R. J. , Keech, A. C. , Colquhoun, D. , Hitman, G. A. , Betteridge, D. J. , Clearfield, M. B. , Downs, J. R. , Colhoun, H. M. , Gotto, A. M. , Ridker, P. M. , Grundy, S. M. & 1 others Kastelein, J. J. P. 5 Aug 2014 In : Journal of the American College of Cardiology. 64, 5, p. 485-494 10 p.

    Research output: Contribution to journalArticle

  25. Faecal haemoglobin concentrations vary with sex and age, but data are not transferable across geography for colorectal cancer screening

    Fraser, C. G., Rubeca, T., Rapi, S., Chen, L-S. & Chen, H-H. Aug 2014 In : Clinical Chemistry and Laboratory Medicine. 52, 8, p. 1211-6 6 p.

    Research output: Contribution to journalArticle

  26. Microvascular decompression for superior oblique myokymia: case report

    Fam, M. D., Scott, C., Forster, A. & Kamel, M. H. Aug 2014 In : British Journal of Neurosurgery. 28, 4, p. 552-5 4 p.

    Research output: Contribution to journalArticle

  27. Reducing patient delay with symptoms of acute coronary syndrome: a research protocol for a systematic review of previous interventions to investigate which behaviour change techniques are associated with effective interventions

    Farquharson, B., Dombrowski, S., Pollock, A., Johnston, M., Treweek, S., Williams, B., Smith, K., Dougall, N., Jones, C. & Pringle, S. Aug 2014 In : Open Heart. 1, 1, 5 p.e000079

    Research output: Contribution to journalArticle

  28. The influence of socioeconomic deprivation on multimorbidity at different ages: a cross-sectional study

    McLean, G., Gunn, J., Wyke, S., Guthrie, B., Watt, G. C. M., Blane, D. N. & Mercer, S. W. 1 Jul 2014 In : British Journal of General Practice. 64, 624, p. e440-e447

    Research output: Contribution to journalArticle

  29. Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Smith, B. H. & 159 others Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H., Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., Vonk, J. M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., Postma, D. S., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y-M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O'Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., Starr, J. M., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., Burkart, K. M., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, O. D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Generation Scotland, Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Jarvelin, M-R., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., Verhamme, F. M., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J. Jul 2014 In : Nature Genetics. 46, 7, p. 669-677 9 p.

    Research output: Contribution to journalArticle

  30. Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

    Norsworthy, P. J., Vandrovcova, J., Thomas, E. R. A., Campbell, A., Kerr, S. M., Biggs, J., Game, L., Soutar, A. K., Smith, B. H., Dominiczak, A. F., Porteous, D. J., Morris, A. D., Generation Scotland & Aitman, T. J. 23 Jun 2014 In : BMC Medical Genetics. 15, 7 p.70

    Research output: Contribution to journalArticle

  31. A hard pill to swallow: a qualitative study of women's experiences of adjuvant endocrine therapy for breast cancer

    Harrow, A., Dryden, R., McCowan, C., Radley, A., Parsons, M., Thompson, A. M. & Wells, M. 12 Jun 2014 In : BMJ Open. 4, 6, 11 p.e005285

    Research output: Contribution to journalArticle

  32. Prediction of liver disease in patients whose liver function tests have been checked in primary care: model development and validation using population-based observational cohorts

    McLernon, D. J., Donnan, P. T., Sullivan, F. M., Roderick, P., Rosenberg, W. M., Ryder, S. D. & Dillon, J. F. 2 Jun 2014 In : BMJ Open. 4, 6, 10 p.e004837

    Research output: Contribution to journalArticle

  33. 60 insulin resistance is associated with all-cause mortality and accelerates the risk of progression to diabetes in non-diabetic heart failure patients

    Mohan, M., Deshmukh, H., Maria Choy, A. & Lang, C. Jun 2014 In : Heart. 100 , s3, p. A34 1 p.

    Research output: Contribution to journalMeeting abstract

  34. A summary of the Iodine Supplementation Study Protocol (I2S2): a UK multicentre randomised controlled trial in preterm infants

    Kayleigh, M. & I2S2 team Jun 2014 In : Neonatology. 105, 4, p. 282-289 8 p.

    Research output: Contribution to journalArticle

  35. Comparative cancer survival in European countries

    Munro, A. J. Jun 2014 In : British Medical Bulletin. 110, 1, p. 5-22 18 p.

    Research output: Contribution to journalArticle

  36. Effectiveness of newspaper advertising for patient recruitment into a clinical trial

    Hapca, A., Jennings, C. G., Wei, L., Wilson, A., MacDonald, T. M. & Mackenzie, I. S. Jun 2014 In : British Journal of Clinical Pharmacology. 77, 6, p. 1064-1072 9 p.

    Research output: Contribution to journalArticle

  37. Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008

    Jones, N. R. V., Fischbacher, C. M., Guthrie, B., Leese, G., Lindsay, R. S., McKnight, J. A., Pearson, D., Philip, S., Sattar, N., Wild, S. H. & Scottish Diabetes Research Network Epidemiology Group Jun 2014 In : Diabetic Medicine. 31, 6, p. 640-646 7 p.

    Research output: Contribution to journalArticle

  38. Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

    Zhou, K., Donnelly, L., Yang, J., Li, M., Deshmukh, H., Van Zuydam, N., Ahlqvist, E., Spencer, C. C., Groop, L., Morris, A. D., Colhoun, H. M., Sham, P. C., McCarthy, M. I., Palmer, C. N. A. & Pearson, E. R. Jun 2014 In : The Lancet Diabetes and Endocrinology. 2, 6, p. 481-487 7 p.

    Research output: Contribution to journalArticle

  39. Contemporary risk of hip fracture in type 1 and type 2 diabetes: a national registry study from Scotland

    Hothersall, E. J., Livingstone, S. J., Looker, H. C., Ahmed, S. F., Cleland, S., Leese, G. P., Lindsay, R. S., McKnight, J., Pearson, D., Philip, S., Wild, S. H. & Colhoun, H. M. May 2014 In : Journal of Bone and Mineral Research. 29, 5, p. 1054-1060 7 p.

    Research output: Contribution to journalArticle

  40. A gender-sensitised weight loss and healthy living programme for overweight and obese men delivered by Scottish Premier League football clubs (FFIT): a pragmatic randomised controlled trial

    Hunt, K., Wyke, S., Gray, C. M., Anderson, A. S., Brady, A., Bunn, C., Donnan, P. T., Fenwick, E., Grieve, E., Lieshman, J., Miller, E., Mutrie, N., Rauchhaus, P., White, A. & Treweek, S. 5 Apr 2014 In : Lancet. 383, 9924, p. 1211-1221 11 p.

    Research output: Contribution to journalArticle

  41. Neuropathic pain in the general population: a systematic review of epidemiological studies

    van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N. Apr 2014 In : PAIN. 155, 4, p. 654-662

    Research output: Contribution to journalArticle

  42. The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial

    Anderson, A. S., Craigie, A. M., Caswell, S., Treweek, S., Stead, M., Macleod, M., Daly, F., Belch, J., Rodger, J., Kirk, A., Ludbrook, A., Rauchhaus, P., Norwood , P., Thompson, J., Wardle, J. & Steele, R. J. C. 7 Mar 2014 In : BMJ. 348, g1823

    Research output: Contribution to journalArticle

  43. A standard for Faecal Immunochemical TesTs for Haemoglobin Evaluation Reporting (FITTER)

    Fraser, C. G., Allison, J. E., Young, G. P., Halloran, S. P. & Seaman, H. Mar 2014 In : Annals of Clinical Biochemistry. 51, 2, p. 301-302 2 p.

    Research output: Contribution to journalLetter

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