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Gene Regulation & Expression

  1. Targetes gene regulation mediated by nucleolar snoRNAs

    Ono, M., Scott, M., Yamada, K., Barton, G., Hutvagner, G. & Lamond, A. Jun 2008 In : FEBS Journal. 275, S1, p. 73-73 1 p.

    Research output: Contribution to journalBook/Film/Article review

  2. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior

    Lee, H., Cho, J. S., Lambacher, N., Lee, J., Lee, S-J., Lee, T. H., Gartner, A. & Koo, H-S. 30 May 2008 In : Journal of Biological Chemistry. 283, 22, p. 14988-14993 6 p.

    Research output: Contribution to journalArticle

  3. Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

    Richard, D. J., Bolderson, E., Cubeddu, L., Wadsworth, R. I. M., Savage, K., Sharma, G. G., Nicolette, M. L., Tsvetanov, S., McIlwraith, M. J., Pandita, R. K., Takeda, S., Hay, R. T., Gautier, J., West, S. C., Paull, T. T., Pandita, T. K., White, M. F. & Khanna, K. K. 29 May 2008 In : Nature. 453, 7195, p. 677-U13 6 p.

    Research output: Contribution to journalArticle

  4. Discovery, in vivo activity and mechanism of action of a small-molecule p53 activator

    Lain, S., Hollick, J. J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Mathers, J., Holland, S. J., Stark, M. J. R., Pass, G., Woods, J., Lane, D. P. & Westwood, N. J. 6 May 2008 In : Cancer Cell. 13, 5, p. 454-463 10 p.

    Research output: Contribution to journalArticle

  5. RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

    Tatham, M. H., Geoffroy, M-C., Shen, L., Plechanovova, A., Hattersley, N., Jaffray, E. G., Palvimo, J. J. & Hay, R. T. May 2008 In : Nature Cell Biology. 10, 5, p. 538-546 9 p.

    Research output: Contribution to journalArticle

  6. Correction: Human topoisomerase 2 alpha conjugates with SUMO-2 (vol 68, pg 2409, 2008)

    Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J. 15 Apr 2008 In : Cancer Research. 68, 8, p. 3076-3076 1 p.

    Research output: Contribution to journalArticle

  7. Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity

    Agostinho, M., Santos, V., Ferreira, F., Costa, R., Cardoso, J., Pinheiro, I., Rino, J., Jaffray, E., Hay, R. T. & Ferreira, J. 1 Apr 2008 In : Cancer Research. 68, 7, p. 2409-2418 10 p.

    Research output: Contribution to journalArticle

  8. NF-kappa B is a critical regulator of the survival of rodent and human hepatic myofibroblasts

    Watson, M. R., Wallace, K., Gieling, R. G., Manas, D. M., Jaffray, E., Hay, R. T., Mann, D. A. & Oakley, F. Apr 2008 In : Journal of Hepatology. 48, 4, p. 589-597 9 p.

    Research output: Contribution to journalArticle

  9. Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathway

    Martin, S. F., Tatham, M. H., Hay, R. T. & Samuel, I. D. W. Apr 2008 In : Protein Science. 17, 4, p. 777-784 8 p.

    Research output: Contribution to journalArticle

  10. p53 activating benzoyl urea and benzoyl thiourea compounds

    Lain, S., Lane, D., Stark, M. J. R., McCarthy, A. R., Hollick, J. J. & Westwood, N. J. 13 Mar 2008 WO2008029096

    Research output: Patent

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