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Gene Regulation and Expression

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  1. Insights into Diphthamide, key Diphtheria Toxin effector

    Abdel-Fattah, W., Scheidt, V., Uthman, S., Stark, M. J. R. & Schaffrath, R. 3-May-2013 5, 5, p. 958-968, 11 p.

    Research output: Contribution to journalArticle

  2. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

    Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T. 15-Apr-2013 In : Biochemical Journal. 451, 2, p. 185-194, 10 p., BJ20130026

    Research output: Contribution to journalArticle

  3. Correlative imaging of fluorescent proteins in resin-embedded plant material

    Bell, K., Mitchell, S., Paultre, D., Posch, M. & Oparka, K. Apr-2013 In : Plant Physiology. 161, 4, p. 1595-1603, 9 p.

    Research output: Contribution to journalArticle

  4. Decoding the SUMO signal

    Hay, R. T. Apr-2013 In : Biochemical Society Transactions. 41, 2, p. 463-473, 11 p.

    Research output: Contribution to journalArticle

  5. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant

    Earnshaw, W. C. , Allshire, R. C. , Black, B. E. , Bloom, K. , Salmon, E. D. , Brinkley, B. R. , Brown, W. , Cheeseman, I. M. , Choo, K. H. A. , Copenhaver, G. P. , DeLuca, J. G. , Luger, K. , Desai, A. , Oegema, K. , Cleveland, D. W. , Diekmann, S. , Erhardt, S. , Fitzgerald-Hayes, M. , Foltz, D. , Fukagawa, T. & 37 others Gassmann, R., Maiato, H., Gerlich, D. W., Glover, D. M., Gorbsky, G. J., Harrison, S. C., Heun, P., Hirota, T., Jansen, L. E. T., Karpen, G., Kops, G. J. P. L., Lampson, M. A., Lens, S. M., Losada, A., Maddox, P. S., Margolis, R. L., Masumoto, H., McAinsh, A. D., Mellone, B. G., O'Neill, R. J., Meraldi, P., Musacchio, A., Scott, K. C., Sullivan, B. A., Straight, A. F., Stukenberg, P. T., Sullivan, K. F., Sunkel, C. E., Swedlow, J. R., Walczak, C. E., Warburton, P. E., Westermann, S., Willard, H. F., Wordeman, L., Yanagida, M., Yen, T. J. & Yoda, K. Apr-2013 In : Chromosome Research. 21, 2, p. 101-106, 6 p.

    Research output: Contribution to journalArticle

  6. Topoisomerase IIα promotes activation of RNA polymerase i transcription by facilitating pre-initiation complex formation

    Ray, S., Panova, T., Miller, G., Volkov, A., Porter, A. C. G., Russell, J., Panov, K. I. & Zomerdijk, J. C. B. M. 19-Mar-2013 In : Nature Communications. 4, 1598

    Research output: Contribution to journalArticle

  7. Identification and functional characterization of FMN2: a regulator of the cyclin-dependent kinase Inhibitor p21

    Yamada, K., Ono, M., Perkins, N. D., Rocha, S. & Lamond, A. I. Mar-2013 In : Molecular Cell. 49, 5, p. 922-933, 12 p.

    Research output: Contribution to journalArticle

  8. DNA-binding regulates site-specific ubiquitination of IRF-1

    Landré, V., Pion, E., Narayan, V., Xirodimas, D. P. & Ball, K. L. 1-Feb-2013 In : Biochemical Journal. 449, 3, p. 707-717, 11 p.

    Research output: Contribution to journalArticle

  9. A sweet TET-a-tete-synergy of TET proteins and O-GlcNAc transferase in transcription

    Mariappa, D., Pathak, S. & van Aalten, D. M. F. 2013 In : EMBO Journal. 32, 5, p. 612-613, 2 p.

    Research output: Contribution to journalEditorial

  10. Germ cell apoptosis and DNA damage responses

    Bailly, A. & Gartner, A. 2013 Germ Cell Development in C. elegans. Schedl, T. (ed.). New York: Springer, Vol. 757, p. 249-276 28 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  11. TfR1 interacts with the IKK complex and is involved in IKK-NF-kappaB signalling

    Kenneth, N. S., Mudie, S., Naron, S. & Rocha, S. 2013 In : Biochemical Journal. 449, p. 275-284

    Research output: Contribution to journalArticle

  12. The amidation step of Diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network

    Uthman, S., Baer, C., Scheidt, V., Liu, S., Ten Have, S., Giorgini, F., Stark, M. J. R. & Schaffrath, R. 2013 In : PLoS Genetics. 9, 2, e1003334

    Research output: Contribution to journalArticle

  13. Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity

    Aillet, F., Lopitz-Otsoa, F., Egaña, I., Hjerpe, R., Fraser, P., Hay, R. T., Rodriguez, M. S. & Lang, V. 20-Dec-2012 In : PLoS ONE. 7, 12, e51672

    Research output: Contribution to journalArticle

  14. Structural plasticity of histones H3–H4 facilitates their allosteric exchange between RbAp48 and ASF1

    Zhang, W., Yyl, M., Ward, R., Sobott, F., Maman, J., Murthy, A., Watson, A., Fedorov, O., Bowman, A., Owen-Hughes, T., El Mkami, H., Murzina, N., Norman, D. G. & Laue, E. 25-Nov-2012 In : Nature Structural & Molecular Biology. 20, 1, p. 29-35

    Research output: Contribution to journalArticle

  15. Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

    McIntosh, D. & Blow, J. J. Oct-2012 In : Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955

    Research output: Contribution to journalArticle

  16. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21-Sep-2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53, 8 p.

    Research output: Contribution to journalArticle

  17. The control of cell energy metabolism by NF-j B transcription factors

    Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S. & Franzoso, G. Sep-2012 In : Immunology. 137, S1, p. 19, 1 p.

    Research output: Contribution to journalMeeting abstract

  18. Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth

    Huart, A-S., MacLaine, N. J., Narayan, V. & Hupp, T. R. 20-Aug-2012 In : PLoS ONE. 7, 8, e43391

    Research output: Contribution to journalArticle

  19. ALDH2 mediates 5-nitrofuran activity in multiple species

    Zhou, L., Ishizaki, H., Spitzer, M., Taylor, K. L., Temperley, N. D., Johnson, S. L., Brear, P., Gautier, P., Zeng, Z., Mitchell, A., Narayan, V., McNeil, E. M., Melton, D. W., Smith, T. K., Tyers, M., Westwood, N. J. & Patton, E. E. 27-Jul-2012 In : Chemistry & Biology. 19, 7, p. 883-892, 10 p.

    Research output: Contribution to journalArticle

  20. The human T-lymphotropic virus type 1 tax protein inhibits nonsense-mediated mRNA decay by interacting with INT6/EIF3E and UPF1

    Mocquet, V., Neusiedler, J., Cluet, D., Robin, J-P., Terme, J-M., Dodon, M. D., Morris, C., Jalinot, P., Rende, F., Ciminale, V., Wittmann, J. & Le Hir, H. 1-Jul-2012 In : Journal of Virology. 86, 14, p. 7530-7543, 14 p.

    Research output: Contribution to journalArticle

  21. Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling

    Sturrock, M., Terry, A. J., Xirodimas, D. P., Thompson, A. M. & Chaplain, M. A. J. Jul-2012 In : Bulletin of Mathematical Biology. 74, 7, p. 1531-1579, 49 p.

    Research output: Contribution to journalArticle

  22. Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore

    Bock, L. J., Pagliuca, C., Alfieri, C., Golfieri, C., Dal Maschio, M., De Wulf, P., Kobayashi, N., Oku, Y., Tanaka, T. U., Grove, R. A., Shrestha, K., Hazbun, T. R., Oldani, A. & Bermejo, R. 1-Jun-2012 In : Nature Cell Biology. 14, 6, p. 614-624, 11 p.

    Research output: Contribution to journalArticle

  23. SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage

    Yin, Y., Seifert, A., Chua, J. S., Maure, J-F., Golebiowski, F. & Hay, R. T. 1-Jun-2012 In : Genes & Development. 26, 11, p. 1196-1208, 13 p.

    Research output: Contribution to journalArticle

  24. Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

    Gillespie, P. J., Gambus, A. & Blow, J. J. Jun-2012 In : Methods. 57, 2, p. 203-13, 11 p.

    Research output: Contribution to journalArticle

  25. Quantitative proteomic analysis of yeast DNA replication proteins

    Kubota, T., Stead, D. A., Hiraga, S., ten Have, S. & Donaldson, A. D. Jun-2012 In : Methods (San Diego, Calif.). 57, 2, p. 196-202, 7 p.

    Research output: Contribution to journalArticle

  26. Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

    Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J. 15-May-2012 In : Journal of Cell Science. 125, 10, p. 2436-2445, 10 p.

    Research output: Contribution to journalArticle

  27. A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture

    Dove, B. K., Surtees, R., Bean, T. J. H., Munday, D., Wise, H. M., Digard, P., Carroll, M. W., Ajuh, P., Barr, J. N. & Hiscox, J. A. May-2012 In : Proteomics. 12, 9, p. 1431-1436, 6 p.

    Research output: Contribution to journalArticle

  28. The p53 isoforms are differentially modified by Mdm2

    Camus, S., Menendez, S., Fernandes, K., Kua, N., Liu, G., Xirodimas, D. P., Lane, D. P. & Bourdon, J-C. 15-Apr-2012 In : Cell Cycle. 11, 8, p. 1646-1655, 10 p.

    Research output: Contribution to journalArticle

  29. Human box C/D snoRNA processing conservation across multiple cell types

    Scott, M. S., Ono, M., Yamada, K., Endo, A., Barton, G. J. & Lamond, A. I. Apr-2012 In : Nucleic Acids Research. 40, 8, p. 3676-3688, 13 p.

    Research output: Contribution to journalArticle

  30. Micrococcal Nuclease Does Not Substantially Bias Nucleosome Mapping

    Allan, J., Fraser, R. M., Owen-Hughes, T. & Keszenman-Pereyra, D. 30-Mar-2012 In : Journal of Molecular Biology. 417, 3, p. 152-164, 13 p.

    Research output: Contribution to journalArticle

  31. Diphtheria disease and genes involved in formation of diphthamide, key effector of the diphtheria toxin

    Uthman, S., Liu, S., Giorgini, F., Stark, M. J. R., Costanzo, M. & Schaffrath, R. 21-Mar-2012 Insight and Control of Infectious Disease in Global Scenario . Roy, P. K. (ed.). Croatia: In Tech - Open Access Publisher, p. 333-357 25 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  32. The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions

    Leidecker, O., Matic, I., Mahata, B., Pion, E. & Xirodimas, D. P. 15-Mar-2012 In : Cell Cycle. 11, 6, p. 1142-1150, 9 p.

    Research output: Contribution to journalArticle

  33. Polypyrimidine Tract Binding Protein (hnRNP I) Is Possibly a Conserved Modulator of miRNA-Mediated Gene Regulation

    Engels, B., Jannot, G., Remenyi, J., Simard, M. J. & Hutvagner, G. 9-Mar-2012 In : PLoS ONE. 7, 3, p. -, 11 p., e33144

    Research output: Contribution to journalArticle

  34. A quantitative spatial proteomics analysis of proteome turnover in human cells

    Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I. 1-Mar-2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  35. Advancing cell biology through proteomics in space and time (PROSPECTS)

    Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, C. V., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Andersen, J. S., Vorm, O., Linial, M., Aebersold, R. & Mann, M. 1-Mar-2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  36. Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway

    Larance, M., Kirkwood, K. J., Xirodimas, D. P., Lundberg, E., Uhlen, M. & Lamond, A. I. 1-Mar-2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  37. OMERO: flexible, model-driven data management for experimental biology

    Allan, C. , Burel, J-M. , Moore, J. , Blackburn, C. , Linkert, M. , Loynton, S. , MacDonald, D. , Moore, W. J. , Neves, C. , Patterson, A. , Porter, M. , Tarkowska, A. , Loranger, B. , Avondo, J. , Lagerstedt, I. , Lianas, L. , Leo, S. , Hands, K. , Hay, R. T. , Patwardhan, A. & 4 others Best, C., Kleywegt, G. J., Zanetti, G. & Swedlow, J. R. 1-Mar-2012 In : Nature Methods. 9, 3, p. 245-253, 9 p.

    Research output: Contribution to journalArticle

  38. Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization

    Ahmad, Y., Boisvert, F-M., Lundberg, E., Uhlen, M. & Lamond, A. I. 1-Mar-2012 In : Molecular & Cellular Proteomics. 11, 3

    Research output: Contribution to journalArticle

  39. Tratamiento exitoso de la necrosis isquémica del glande poscircuncisión con oxígeno hiperbárico y pentoxifilina intravenosa

    Elemen, L., Akay, A., Topçu, K. & Gürcan, N. I. 1-Mar-2012 In : Actas Urologicas Espanolas. 36, 3, p. 200-201, 2 p.

    Research output: Contribution to journalArticle

  40. Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction

    Pourkarimi, E., Greiss, S. & Gartner, A. Mar-2012 In : Cell Death & Differentiation. 19, 3, p. 406-415, 10 p.

    Research output: Contribution to journalArticle

  41. Raf1 is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification

    Buscaino, A., White, S. A., Houston, D. R., Lejeune, E., Simmer, F., de Lima Alves, F., Diyora, P. T., Bayne, E. H., Rappsilber, J., Allshire, R. C. & Urano, T. 1-Feb-2012 In : PLoS Genetics. 8, 2, e1002499

    Research output: Contribution to journalArticle

  42. Scale integration: the structure and dynamics of macromolecular assemblies, cells and tissues

    Swedlow, J. & Danuser, G. 1-Feb-2012 In : Current Opinion in Cell Biology. 24, 1, p. 1-3, 3 p.

    Research output: Contribution to journalArticle

  43. The dynamics of replication licensing in live Caenorhabditis elegans embryos

    Sonneville, R., Querenet, M., Craig, A., Gartner, A. & Blow, J. J. 23-Jan-2012 In : Journal of Cell Biology. 196, 2, p. 233-246, 14 p.

    Research output: Contribution to journalArticle

  44. The shark in us: Learning about the evolution of the p53 regulatory circuit

    Rutkowski, R. & Gartner, A. 15-Jan-2012 In : Cell Cycle. 11, 2, p. 216-217, 2 p.

    Research output: Contribution to journalComment/debate

  45. Detection and quantitation of SUMO chains by mass spectrometry

    Matic, I. & Hay, R. T. 1-Jan-2012 Methods in Molecular Biology. Vol. 832, p. 239-247 9 p.

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  46. Innovation in biological microscopy: current status and future directions

    Swedlow, J. R. 1-Jan-2012 In : BioEssays.

    Research output: Contribution to journalArticle

  47. Making sense of transcribing chromatin

    Owen-Hughes, T. & Gkikopoulos, T. 1-Jan-2012 In : Current Opinion in Cell Biology.

    Research output: Contribution to journalArticle

  48. Methods for studying the DNA damage response in the Caenorhabdatis elegans germ line

    Craig, A. L., Moser, S. C., Bailly, A. . & Gartner, A. 1-Jan-2012 In : Methods in Cell Biology. 107, p. 321-352, 32 p.

    Research output: Contribution to journalArticle

  49. Modulation of activation-associated host cell gene expression by the apicomplexan parasite Theileria annulata

    Durrani, Z., Weir, W., Pillai, S., Shiels, B. & Kinnaird, J. 1-Jan-2012 In : Cellular Microbiology.

    Research output: Contribution to journalArticle

  50. Software tools, data structures, and interfaces for microscope imaging

    Stuurman, N. & Swedlow, J. R. 1-Jan-2012 In : Cold Spring Harbor Protocols. 7, 1, p. 50-61, 12 p.

    Research output: Contribution to journalArticle

  51. Sulfyhydryl-reactive site-directed cross-linking as a method for probing the tetrameric structure of histones H3 and H4

    Bowman, A. & Owen-Hughes, T. 1-Jan-2012 Methods in Molecular Biology. Vol. 833, p. 373-387 15 p.

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  52. The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4

    Watson, A. A., Zhang, W., Edlich, C., Chen, Y., Laue, E. D., Mahajan, P., Berridge, G., Burgess-Brown, N. A., Gileadi, O., Mertens, H. D. T., Svergun, D. I., Deery, M. J., Pham, P., Du, X., Bartke, T., Kouzarides, T., Wiechens, N. & Owen-Hughes, T. 1-Jan-2012 In : Journal of Molecular Biology.

    Research output: Contribution to journalArticle

  53. Chromatin as an oxygen sensor and active player in the hypoxia response

    Melvin, A. & Rocha, S. Jan-2012 In : Cellular Signalling. 24, 1, p. 35-43, 9 p.

    Research output: Contribution to journalScientific review

  54. hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies

    Drakou, C. E., Malekkou, A., Hayes, J. M., Lederer, C. W., Leonidas, D. D., Oikonomakos, N. G., Lamond, A. I., Santama, N. & Zographos, S. E. Jan-2012 In : Proteins: Structure, Function, and Bioinformatics. 80, 1, p. 206-220, 15 p.

    Research output: Contribution to journalArticle

  55. Why are patients with small cell lung cancer (SCLC) not given chemotherapy?

    Khan, M. I., Brown, E. J., Lord, H., Allan, C., Sim, L., Buckle, F. & Rankin, E. M. Jan-2012 In : Lung Cancer. 75, p. S59-S59, 1 p.

    Research output: Contribution to journalArticle

  56. ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA

    De Cian, A., Praly, E., Ding, F., Singh, V., Lavelle, C., Le Cam, E., Croquette, V., Pietrement, O. & Bensimon, D. 2012 In : PLoS ONE. 7, 2, p. -, 13 p., e31845

    Research output: Contribution to journalArticle

  57. Cytosolic entry of shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active hrd1p

    Li, S., Spooner, R. A., Hampton, R. Y., Lord, J. M. & Roberts, L. M. 2012 In : PLoS ONE. 7, 7, e41119

    Research output: Contribution to journalArticle

  58. HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

    Durán, R. V., Mackenzie, E. D., Boulahbel, H., Frezza, C., Heiserich, L., Tardito, S., Bussolati, O., Rocha, S., Hall, M. N. & Gottlieb, E. 2012 In : Oncogene. 12 p.

    Research output: Contribution to journalArticle

  59. Highly potent activation of Nrf2 by topical tricyclic bis(cyano enone): Implications for protection against UV radiation during thiopurine therapy

    Kalra, S., Knatko, E. V., Zhang, Y., Honda, T., Yamamoto, M. & Dinkova-Kostova, A. T. 2012 In : Cancer Prevention Research. 5, 7, p. 973-981, 9 p.

    Research output: Contribution to journalArticle

  60. Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

    Ganguly, N. 2012 In : Cellular Oncology. 35, 2, p. 67-76, 10 p.

    Research output: Contribution to journalScientific review

  61. Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21

    de Wever, V., Lloyd, D. C., Nasa, I., Nimick, M., Trinkle-Mulcahy, L., Gourlay, R., Morrice, N. & Moorhead, G. B. G. 2012 In : PLoS ONE. 7, 6, e39510

    Research output: Contribution to journalArticle

  62. LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis

    Liu, B., Du, H., Rutkowski, R., Gartner, A. & Wang, X. 2012 In : Science. 337, 6092, p. 351-354, 4 p.

    Research output: Contribution to journalArticle

  63. Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

    Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J. & Chubb, J. R. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7350-7355, 6 p.

    Research output: Contribution to journalArticle

  64. OMERO: Open source scientific image data management platform

    Swedlow, J. 2012

    Research output: Non-textual formSoftware

  65. Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway

    Arabi, A., Ullah, K., Branca, R. M. M., Johansson, J., Bandarra, D., Haneklaus, M., Fu, J., Ariës, I., Nilsson, P., Den Boer, M. L., Pokrovskaja, K., Grandér, D., Xiao, G., Rocha, S., Lehtiö, J. & Sangfelt, O. 2012 In : Nature Communications. 3, 976

    Research output: Contribution to journalArticle

  66. Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites

    Matic, I., Ahel, I. & Hay, R. T. 2012 In : Nature Methods. 9, 8, p. 771-772, 2 p.

    Research output: Contribution to journalArticle

  67. Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

    Plechanovová, A., Jaffray, E. G., Tatham, M. H., Naismith, J. H. & Hay, R. T. 2012 In : Nature. 489, 7414, p. 115-120, 5 p.

    Research output: Contribution to journalArticle

  68. The adenomatous polyposis Coli protein contributes to normal compaction of mitotic chromatin

    Dikovskaya, D., Khoudoli, G., Newton, I. P., Chadha, G. S., Klotz, D., Visvanathan, A., Lamond, A., Swedlow, J. R. & Nathke, I. S. 2012 In : PLoS ONE. 7, 6, e38102

    Research output: Contribution to journalArticle

  69. The Function of Snodprot in the Cerato-Platanin Family from Dactylellina cionopaga in Nematophagous Fungi

    Yu, H., Duan, J., Wang, B. & Jiang, X. 2012 In : Bioscience biotechnology and biochemistry. 76, 10, p. 1835-1842, 8 p.

    Research output: Contribution to journalArticle

  70. Kinetochore-Dependent Microtubule Rescue Ensures Their Efficient and Sustained Interactions in Early Mitosis

    Gandhi, S. R., Gierlinski, M., Mino, A., Tanaka, K., Kitamura, E., Clayton, L. & Tanaka, T. U. 15-Nov-2011 In : Developmental Cell. 21, 5, p. 920-933, 14 p.

    Research output: Contribution to journalArticle

  71. From snoRNA to miRNA: Dual function regulatory non-coding RNAs

    Scott, M. S. & Ono, M. 1-Nov-2011 In : Biochimie. 93, 11, p. 1987-1992, 6 p.

    Research output: Contribution to journalArticle

  72. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH

    Melvin, A., Mudie, S. & Rocha, S. 1-Nov-2011 In : Molecular Biology of the Cell. 22, 21, p. 4171-4181, 11 p.

    Research output: Contribution to journalArticle

  73. The Opportunistic Pathogen Serratia marcescens Utilizes Type VI Secretion To Target Bacterial Competitors

    Murdoch, S. L., Trunk, K., English, G., Fritsch, M. J., Pourkarimi, E. & Coulthurst, S. J. Nov-2011 In : Journal of Bacteriology. 193, 21, p. 6057-6069, 13 p.

    Research output: Contribution to journalArticle

  74. CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

    Franz, A., Orth, M., Pirson, P. A., Sonneville, R., Blow, J. J., Gartner, A., Stemmann, O. & Hoppe, T. 7-Oct-2011 In : Molecular Cell. 44, 1, p. 85-96, 12 p.

    Research output: Contribution to journalArticle

  75. The breath between us

    Spence, P. & Rocha, S. 6-Oct-2011

    Research output: Non-textual formPerformance

  76. Comparison of bipolar electrosurgical devices with ligatures and endoclips in the rat appendicitis model

    Elemen, L., Akay, A., Yazir, Y., Ceylan, S., Boyacioǧlu, Z. & Ceyran, B. 1-Oct-2011 In : Journal of Pediatric Surgery. 46, 10, p. 1923-1929, 7 p.

    Research output: Contribution to journalArticle

  77. Absolute SILAC-compatible expression strain allows SUMO-2 copy number determination in clinical samples

    Matic, I., Jaffray, E. G., Oxenham, S. K., Groves, M. J., Barratt, C. L. R., Tauro, S., Stanley-Wall, N. R. & Hay, R. T. Oct-2011 In : Journal of Proteome Research. 10, 10, p. 4869-4875, 7 p.

    Research output: Contribution to journalArticle

  78. An intranucleolar body associated with rDNA

    Hutten, S., Prescott, A., James, J., Riesenberg, S., Boulon, S., Lam, Y. W. & Lamond, A. I. Oct-2011 In : Chromosoma. 120, 5, p. 481-499, 19 p.

    Research output: Contribution to journalArticle

  79. Mechanisms for ATP-dependent chromatin remodelling: the means to the end

    Flaus, A. & Owen-Hughes, T. Oct-2011 In : FEBS Journal. 278, 19, p. 3579-3595, 17 p.

    Research output: Contribution to journalScientific review

  80. NF-kappa B controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration

    Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S. & Franzoso, G. Oct-2011 In : Nature Cell Biology. 13, 10, p. 1272-U234, 18 p.

    Research output: Contribution to journalArticle

  81. Quantitative Proteomics and Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing Radiation

    Moore, H. M., Bai, B., Boisvert, F-M., Latonen, L., Rantanen, V., Simpson, J. C., Pepperkok, R., Lamond, A. I. & Laiho, M. Oct-2011 In : Molecular & Cellular Proteomics. 10, 10, p. -, 15 p., M111.009241.

    Research output: Contribution to journalArticle

  82. Snf2-family proteins: chromatin remodellers for any occasion

    Ryan, D. P. & Owen-Hughes, T. Oct-2011 In : Current Opinion in Chemical Biology. 15, 5, p. 649-656, 8 p.

    Research output: Contribution to journalScientific review

  83. Stable-isotope labeling with amino acids in nematodes

    Larance, M., Bailly, A. P., Pourkarimi, E., Hay, R. T., Buchanan, G., Coulthurst, S., Xirodimas, D. P., Gartner, A. & Lamond, A. I. Oct-2011 In : Nature Methods. 8, 10, p. 849-851, 3 p.

    Research output: Contribution to journalArticle

  84. SUMOylation plays an essential role in human hepatocyte differentiation and cellular homeostasis

    Hannoun, Z., Jaffray, E., Greenhough, S., Medine, C. N., Forbes, S. J., Wilmut, I., Iredale, J. P., Hay, R. T. & Hay, D. C. Oct-2011 In : Hepatology. 54, S1, p. 958A-958A, 1 p.

    Research output: Contribution to journalSpecial issue

  85. A role for Snf2-related nucleosome-spacing enzymes in genome-wide nucleosome organization

    Gkikopoulos, T., Schofield, P., Singh, V., Pinskaya, M., Mellor, J., Smolle, M., Workman, J. L., Barton, G. J. & Owen-Hughes, T. 23-Sep-2011 In : Science. 333, 6050, p. 1758-1760, 3 p.

    Research output: Contribution to journalArticle

  86. TAF1B Is a TFIIB-Like Component of the Basal Transcription Machinery for RNA Polymerase I

    Naidu, S., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M. 16-Sep-2011 In : Science. 333, 6049, p. 1640-1642, 3 p.

    Research output: Contribution to journalArticle

  87. LimsPortal and BonsaiLIMS: development of a lab information management system for translational medicine

    Bath, T. G., Bozdag, S., Afzal, V. & Crowther, D. 15-Sep-2011 In : Source code for biology and medicine. 6, p. 9

    Research output: Contribution to journalArticle

  88. The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration

    Msaki, A., Sanchez, A. M., Koh, L. F., Barre, B., Rocha, S., Perkins, N. D. & Johnson, R. F. 1-Sep-2011 In : Molecular Biology of the Cell. 22, 17, p. 3032-3040, 9 p.

    Research output: Contribution to journalArticle

  89. Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity

    Sasaki, T., Li, A., Gillespie, P. J., Blow, J. J. & Gilbert, D. M. Sep-2011 In : Nucleus. 2, 5, p. 455-464

    Research output: Contribution to journalArticle

  90. In the family with ubiquitin

    Alexandru, G., Pariente, N. & Xirodimas, D. Sep-2011 In : EMBO Reports. 12, 9, p. 880-882, 3 p.

    Research output: Contribution to journalEditorial

  91. Mechanism of ubiquitylation by dimeric RING ligase RNF4

    Plechanovova, A., Jaffray, E. G., McMahon, S. A., Johnson, K. A., Navratilova, I., Naismith, J. H. & Hay, R. T. Sep-2011 In : Nature Structural & Molecular Biology. 18, 9, p. 1052-U115, 9 p.

    Research output: Contribution to journalArticle

  92. A novel reporter of notch signalling indicates regulated and random notch activation during vertebrate neurogenesis

    Vilas-Boas, F., Fior, R., Swedlow, J. R., Storey, K. G. & Henrique, D. 31-Aug-2011 In : BMC Molecular Biology. 9, p. -, 16 p., 58

    Research output: Contribution to journalArticle

  93. Exo70, a subunit of the exocyst complex, interacts with SNEVhPrp19/hPso4 and is involved in pre-mRNA splicing

    Dellago, H., Loescher, M., Ajuh, P., Ryder, U., Kaisermayer, C., Grillari-Voglauer, R., Fortschegger, K., Gross, S., Gstraunthaler, A., Borth, N., Eisenhaber, F., Lamond, A. I. & Grillari, J. 15-Aug-2011 In : Biochemical Journal. 438, p. 81-91, 11 p.

    Research output: Contribution to journalArticle

  94. PChopper: high throughput peptide prediction for MRM/SRM transition design

    Afzal, V., Huang, J. T-J., Atrih, A. & Crowther, D. J. 15-Aug-2011 In : BMC Bioinformatics. 12, p. -, 9 p., 338

    Research output: Contribution to journalArticle

  95. OMX: a new platform for multimodal, multichannel wide-field imaging

    Dobbie, I. M., King, E., Parton, R. M., Carlton, P. M., Sedat, J. W., Swedlow, J. R. & Davis, I. 1-Aug-2011 In : Cold Spring Harbor Protocols. 6, 8, p. 899-909, 11 p.

    Research output: Contribution to journalArticle

  96. Regulation of Caenorhabditis elegans p53/CEP-1-Dependent Germ Cell Apoptosis by Ras/MAPK Signaling

    Rutkowski, R., Dickinson, R., Stewart, G., Craig, A., Schimpl, M., Keyse, S. M. & Gartner, A. Aug-2011 In : PLoS Genetics. 7, 8, p. -, 21 p., e1002238

    Research output: Contribution to journalArticle

  97. The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

    Ryan, D. P., Sundaramoorthy, R., Martin, D., Singh, V. & Owen-Hughes, T. 6-Jul-2011 In : EMBO Journal. 30, 13, p. 2596-2609, 14 p.

    Research output: Contribution to journalArticle

  98. Quantitative Proteomic Analysis of Chromatin Reveals that Ctf18 Acts in the DNA Replication Checkpoint

    Kubota, T., Hiraga, S., Yamada, K., Lamond, A. I. & Donaldson, A. D. Jul-2011 In : Molecular & Cellular Proteomics. 10, 7, p. -, 14 p., M110.005561.

    Research output: Contribution to journalArticle

  99. Comparative proteomic analysis identifies a role for SUMO in protein quality control

    Tatham, M. H., Matic, I., Mann, M. & Hay, R. T. 21-Jun-2011 In : Science Signaling. 4, 178, p. -, 12 p., rs4

    Research output: Contribution to journalArticle

  100. Erratum: Further insights into the mechanism of hypoxia-induced NFκB (Cell Cycle (2011) 10 (879-82))

    Melvin, A., Mudie, S. & Rocha, S. 15-Jun-2011 In : Cell Cycle. 10, 12, p. 2041, 1 p.

    Research output: Contribution to journalArticle

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